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Eliezer Masliah

Title(s)Emeritus Professor, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Systems biology of HIV, methamphetamine and antiretrovirals interactions
    NIH R01DA041750May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Regulation of the oligodendroglial accumulation of alpha-synuclein in Multiple System Atrophy
    NIH R01NS092803Apr 1, 2016 - Mar 31, 2021
    Role: Principal Investigator
    Clearance Pathways in the CNS in Aging and HIV
    NIH R01AG043384May 1, 2012 - Apr 30, 2018
    Role: Principal Investigator
    La Jolla Interdisciplinary Neuroscience Center Cores
    NIH P30NS076411Sep 26, 2011 - May 31, 2016
    Role: Co-Investigator
    La Jolla-Parkinson's Disease Center Grant
    NIH P01ES016738Jul 16, 2010 - Sep 10, 2010
    Role: Co-Investigator
    Molecular Mechanisms linking Aging, Abeta Proteotoxicity and Neurodegeneration
    NIH P01AG031097Feb 1, 2009 - Jan 31, 2014
    Role: Co-Investigator
    Proteinopathies of the Aging Central Nervous System
    NIH P01AG022074Jun 15, 2003 - Nov 30, 2013
    Role: Co-Investigator
    Mechanisms of Neuroprotection in HIV Encephalitis
    NIH R01MH062962Feb 20, 2002 - Mar 31, 2018
    Role: Principal Investigator
    a-Synuclein vulnerability mechanisms and therapeutics in Alzheimer's Disease
    NIH R01AG018440Sep 1, 2001 - Aug 31, 2006
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH P30MH062512Apr 24, 2001 - Nov 30, 2005
    Role: Co-Investigator
    a-synuclein clearance strategies for the treatment of Lewy body disease
    NIH R37AG018440Jul 1, 2000 - Jun 30, 2016
    Role: Principal Investigator
    NEUROAIDS: EFFECTS OF METHAMPHETAMINE AND HCV
    NIH P01DA012065Jul 1, 1999 - Jun 30, 2004
    Role: Co-Investigator
    Gene Therapy for Alzheimer's Disease
    NIH P01AG010435Mar 1, 1998 - Aug 31, 2010
    Role: Co-Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050May 15, 1997 - Dec 11, 1993
    Role: Co-Investigator
    UCSD Alzheimer's Disease Research Center P50
    NIH P50AG005131Apr 1, 1997 - Aug 31, 1989
    Role: Co-Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    BASIS OF SYNAPTIC PATHOLOGY IN ALZHEIMERS DISEASE
    NIH R01AG010689Sep 29, 1991 - Nov 30, 2002
    Role: Principal Investigator
    HIV NEUROBEHAVIORAL RESEARCH CENTER
    NIH P50MH045294Jun 1, 1989 - Nov 30, 2000
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2. Neurobiol Dis. 2021 Jan 28; 105277. Ngolab J, Canchi S, Rasool S, Elmaarouf A, Thomas K, Sarsoza F, Grundman J, Mante M, Florio J, Nandankar N, Korouri S, Zago W, Masliah E, Rissman RA. PMID: 33516874.
      View in: PubMed   Mentions:    Fields:    
    2. Microvascular Injury in the Brains of Patients with Covid-19. N Engl J Med. 2020 Dec 30. Lee MH, Perl DP, Nair G, Li W, Maric D, Murray H, Dodd SJ, Koretsky AP, Watts JA, Cheung V, Masliah E, Horkayne-Szakaly I, Jones R, Stram MN, Moncur J, Hefti M, Folkerth RD, Nath A. PMID: 33378608.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol. 2020 Dec 23. Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunuan V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF. PMID: 33367843.
      View in: PubMed   Mentions:    Fields:    
    4. ANA Webinars: Clinical and basic research resilience during COVID-19. Ann Clin Transl Neurol. 2020 Dec 15. Johansen MC, Jones-London M, Koroshetz W, Masliah E, Nath A, Whittemore V, McArthur JC. PMID: 33321003.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease. Science. 2020 Dec 03. Nakamura T, Oh CK, Liao L, Zhang X, Lopez KM, Gibbs D, Deal AK, Scott HR, Spencer B, Masliah E, Rissman RA, Yates JR, Lipton SA. PMID: 33273062.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Understanding Creutzfeldt-Jackob disease from a viewpoint of amyloidogenic evolvability. Prion. 2020 12; 14(1):1-8. Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Waragai M, Masliah E, Takenouchi T. PMID: 32375593.
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    7. Intracellular A53T Mutant a-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration. Front Cell Dev Biol. 2020; 8:561963. Regensburger M, Stemick J, Masliah E, Kohl Z, Winner B. PMID: 33262984.
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    8. Connecting Alzheimer's Disease With Diabetes Mellitus Through Amyloidogenic Evolvability. Front Aging Neurosci. 2020; 12:576192. Ho G, Takamatsu Y, Wada R, Sugama S, Waragai M, Takenouchi T, Masliah E, Hashimoto M. PMID: 33192467.
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    9. LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies. Sci Transl Med. 2020 Oct 14; 12(565). Kim C, Beilina A, Smith N, Li Y, Kim M, Kumaran R, Kaganovich A, Mamais A, Adame A, Iba M, Kwon S, Lee WJ, Shin SJ, Rissman RA, You S, Lee SJ, Singleton AB, Cookson MR, Masliah E. PMID: 33055242.
      View in: PubMed   Mentions:    Fields:    
    10. Author Correction: Cellular senescence and Alzheimer disease: the egg and the chicken scenario. Nat Rev Neurosci. 2020 10; 21(10):587. Saez-Atienzar S, Masliah E. PMID: 32792667.
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    11. The innate immunity protein IFITM3 modulates ?-secretase in Alzheimer's disease. Nature. 2020 10; 586(7831):735-740. Hur JY, Frost GR, Wu X, Crump C, Pan SJ, Wong E, Barros M, Li T, Nie P, Zhai Y, Wang JC, Tcw J, Guo L, McKenzie A, Ming C, Zhou X, Wang M, Sagi Y, Renton AE, Esposito BT, Kim Y, Sadleir KR, Trinh I, Rissman RA, Vassar R, Zhang B, Johnson DS, Masliah E, Greengard P, Goate A, Li YM. PMID: 32879487.
      View in: PubMed   Mentions: 7     Fields:    
    12. Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate a-synuclein pathology. Acta Neuropathol Commun. 2020 08 04; 8(1):123. PMID: 32753049.
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    13. Correction to: A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders. J Neurovirol. 2020 08; 26(4):509-510. Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. PMID: 32632672.
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    14. Neuroinflammation is associated with infiltration of T cells in Lewy body disease and a-synuclein transgenic models. J Neuroinflammation. 2020 Jul 17; 17(1):214. Iba M, Kim C, Sallin M, Kwon S, Verma A, Overk C, Rissman RA, Sen R, Sen JM, Masliah E. PMID: 32680537.
      View in: PubMed   Mentions: 1     Fields:    
    15. The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. Neurotherapeutics. 2020 07; 17(3):1061-1074. Marschallinger J, Altendorfer B, Rockenstein E, Holztrattner M, Garnweidner-Raith J, Pillichshammer N, Leister I, Hutter-Paier B, Strempfl K, Unger MS, Chishty M, Felder T, Johnson M, Attems J, Masliah E, Aigner L. PMID: 32072462.
      View in: PubMed   Mentions:    Fields:    
    16. Immunotherapies for Aging-Related Neurodegenerative Diseases-Emerging Perspectives and New Targets. Neurotherapeutics. 2020 07; 17(3):935-954. Kwon S, Iba M, Kim C, Masliah E. PMID: 32347461.
      View in: PubMed   Mentions: 1     Fields:    
    17. Cellular senescence and Alzheimer disease: the egg and the chicken scenario. Nat Rev Neurosci. 2020 08; 21(8):433-444. Saez-Atienzar S, Masliah E. PMID: 32601397.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    18. NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models. Mol Psychiatry. 2020 May 29. Ghatak S, Dolatabadi N, Gao R, Wu Y, Scott H, Trudler D, Sultan A, Ambasudhan R, Nakamura T, Masliah E, Talantova M, Voytek B, Lipton SA. PMID: 32467645.
      View in: PubMed   Mentions: 4     Fields:    
    19. The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer's Disease and Parkinson's Disease. Mol Neurobiol. 2020 Jul; 57(7):2959-2980. Monzio Compagnoni G, Di Fonzo A, Corti S, Comi GP, Bresolin N, Masliah E. PMID: 32445085.
      View in: PubMed   Mentions: 1     Fields:    
    20. A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders. J Neurovirol. 2020 08; 26(4):496-508. Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. PMID: 32394397.
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    21. Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2020 05; 139(5):959-962. van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. PMID: 31955222.
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    22. Role of Alterations in Protein Kinase p38? in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and a-Synuclein Transgenic Models. Front Neurosci. 2020; 14:286. Iba M, Kim C, Florio J, Mante M, Adame A, Rockenstein E, Kwon S, Rissman R, Masliah E. PMID: 32296304.
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    23. Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability? Front Endocrinol (Lausanne). 2020; 11:108. Waragai M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 32194507.
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    24. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathol Commun. 2020 01 29; 8(1):5. Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Morgan K, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Trojanowski JQ, Serrano GE, Beach TG, Lesage S, Galasko D, Masliah E, Santana I, Pastor P, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Pickering-Brown S, Mann D, Halliday G, Stone DJ, Dickson DW, Hardy J, Singleton A, Guerreiro R, Bras J. PMID: 31996268.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. NIA workshop on senescence in brain aging and Alzheimer's disease and its related dementias. Geroscience. 2020 04; 42(2):389-396. DiBattista AM, Sierra F, Masliah E. PMID: 31933065.
      View in: PubMed   Mentions: 1     Fields:    
    26. Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain. 2020 01 01; 143(1):234-248. Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ, Pantelyat A, Hillis AE, Dawson TM, Rosenthal LS, Albert MS, Resnick SM, Ferrucci L, Morris CM, Pletnikova O, Troncoso J, Grosset D, Lesage S, Corvol JC, Brice A, Noyce AJ, Masliah E, Wood N, Hardy J, Shulman LM, Jankovic J, Shulman JM, Heutink P, Gasser T, Cannon P, Scholz SW, Morris H, Cookson MR, Nalls MA, Gan-Or Z, Singleton AB. PMID: 31755958.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. Adiponectin Paradox as a Therapeutic Target in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(4):1249-1253. Waragai M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 32623396.
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    28. Aging: therapeutics for a healthy future. Neurosci Biobehav Rev. 2020 01; 108:453-458. Hodgson R, Kennedy BK, Masliah E, Scearce-Levie K, Tate B, Venkateswaran A, Braithwaite SP. PMID: 31783058.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    29. Non-toxic HSC Transplantation-Based Macrophage/Microglia-Mediated GDNF Delivery for Parkinson's Disease. Mol Ther Methods Clin Dev. 2020 Jun 12; 17:83-98. Chen C, Guderyon MJ, Li Y, Ge G, Bhattacharjee A, Ballard C, He Z, Masliah E, Clark RA, O'Connor JC, Li S. PMID: 31890743.
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    30. Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of a-Synuclein Protect Against Diverse a-Synuclein Mediated Dysfunctions. Sci Rep. 2019 11 18; 9(1):16947. Tóth G, Neumann T, Berthet A, Masliah E, Spencer B, Tao J, Jobling MF, Gardai SJ, Bertoncini CW, Cremades N, Bova M, Ballaron S, Chen XH, Mao W, Nguyen P, Tabios MC, Tambe MA, Rochet JC, Junker HD, Schwizer D, Sekul R, Ott I, Anderson JP, Szoke B, Hoffman W, Christodoulou J, Yednock T, Agard DA, Schenk D, McConlogue L. PMID: 31740740.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies. Exp Neurobiol. 2019 Oct 31; 28(5):547-553. Kwon S, Iba M, Masliah E, Kim C. PMID: 31698547.
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    32. A compendium of promoter-centered long-range chromatin interactions in the human genome. Nat Genet. 2019 10; 51(10):1442-1449. Jung I, Schmitt A, Diao Y, Lee AJ, Liu T, Yang D, Tan C, Eom J, Chan M, Chee S, Chiang Z, Kim C, Masliah E, Barr CL, Li B, Kuan S, Kim D, Ren B. PMID: 31501517.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    33. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. PMID: 31417202.
      View in: PubMed   Mentions: 2     Fields:    
    34. Preclinical development of a high affinity a-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular a-synuclein and attenuate a-synuclein spreading in vivo. Neurobiol Dis. 2019 12; 132:104582. Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, Fraser G, McFarlane M, Rockenstein E, Spencer B, Masliah E, Spillantini MG, Tan K, Billinton A, Vaughan T, Chessell I, Perkinton MS. PMID: 31445162.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    35. Effects of single and combined immunotherapy approach targeting amyloid ß protein and a-synuclein in a dementia with Lewy bodies-like model. Alzheimers Dement. 2019 09; 15(9):1133-1148. Mandler M, Rockenstein E, Overk C, Mante M, Florio J, Adame A, Kim C, Santic R, Schneeberger A, Mattner F, Schmidhuber S, Galabova G, Spencer B, Masliah E, Rissman RA. PMID: 31378574.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    36. NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology. Cell Mol Immunol. 2020 03; 17(3):283-299. He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, Hu T, Wu L, Masliah E, Huang S, Cao H. PMID: 31320730.
      View in: PubMed   Mentions: 4     Fields:    
    37. Could changing the course of Alzheimer's disease pathology with immunotherapy prevent dementia? Brain. 2019 07 01; 142(7):1853-1855. Overk C, Masliah E. PMID: 31505546.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    38. Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-a-synuclein-A53T mouse model, correlating with increased nitration and aggregation of a-synuclein and exacerbation of motor impairment. Free Radic Biol Med. 2019 09; 141:115-140. Maki RA, Holzer M, Motamedchaboki K, Malle E, Masliah E, Marsche G, Reynolds WF. PMID: 31175983.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    39. A cullin-RING ubiquitin ligase targets exogenous a-synuclein and inhibits Lewy body-like pathology. Sci Transl Med. 2019 06 05; 11(495). Gerez JA, Prymaczok NC, Rockenstein E, Herrmann US, Schwarz P, Adame A, Enchev RI, Courtheoux T, Boersema PJ, Riek R, Peter M, Aguzzi A, Masliah E, Picotti P. PMID: 31167929.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    40. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2019 08; 138(2):237-250. van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. PMID: 31131421.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    41. Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease. Acta Neuropathol Commun. 2019 05 17; 7(1):77. Shanbhag NM, Evans MD, Mao W, Nana AL, Seeley WW, Adame A, Rissman RA, Masliah E, Mucke L. PMID: 31101070.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    42. HIV and Alzheimer's disease: complex interactions of HIV-Tat with amyloid ß peptide and Tau protein. J Neurovirol. 2019 10; 25(5):648-660. Hategan A, Masliah E, Nath A. PMID: 31016584.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    43. Heritability and genetic variance of dementia with Lewy bodies. Neurobiol Dis. 2019 07; 127:492-501. Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, Ansorge O, Clarimon J, Lleo A, Morenas-Rodriguez E, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Serrano GE, Beach TG, Lesage S, Galasko D, Masliah E, Santana I, Pastor P, Diez-Fairen M, Aguilar M, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Graff-Radford N, Cairns NJ, Morris JC, Pickering-Brown S, Mann D, Halliday GM, Hardy J, Trojanowski JQ, Dickson DW, Singleton A, Stone DJ, Bras J. PMID: 30953760.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model. Neurobiol Dis. 2019 07; 127:390-397. Okamoto SI, Prikhodko O, Pina-Crespo J, Adame A, McKercher SR, Brill LM, Nakanishi N, Oh CK, Nakamura T, Masliah E, Lipton SA. PMID: 30928642.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    45. Systemic peptide mediated delivery of an siRNA targeting a-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease. Neurobiol Dis. 2019 07; 127:163-177. Spencer B, Trinh I, Rockenstein E, Mante M, Florio J, Adame A, El-Agnaf OMA, Kim C, Masliah E, Rissman RA. PMID: 30849508.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    46. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. PMID: 30820047.
      View in: PubMed   Mentions: 181     Fields:    Translation:Humans
    47. Pathogenesis of age-related HIV neurodegeneration. J Neurovirol. 2019 10; 25(5):622-633. Mackiewicz MM, Overk C, Achim CL, Masliah E. PMID: 30790184.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    48. Assessment of APOE in atypical parkinsonism syndromes. Neurobiol Dis. 2019 07; 127:142-146. Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, Dawson TM, Rosenthal LS, Houlden H, Pletnikova O, Troncoso J, Scholz SW. PMID: 30798004.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles. Sci Rep. 2019 02 06; 9(1):561. Snow AD, Castillo GM, Nguyen BP, Choi PY, Cummings JA, Cam J, Hu Q, Lake T, Pan W, Kastin AJ, Kirschner DA, Wood SG, Rockenstein E, Masliah E, Lorimer S, Tanzi RE, Larsen L. PMID: 30728442.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    50. Oligodendroglial a-synucleinopathy-driven neuroinflammation in multiple system atrophy. Brain Pathol. 2019 05; 29(3):380-396. Hoffmann A, Ettle B, Battis K, Reiprich S, Schlachetzki JCM, Masliah E, Wegner M, Kuhlmann T, Riemenschneider MJ, Winkler J. PMID: 30444295.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    51. Transgenerational Interaction of Alzheimer's Disease with Schizophrenia through Amyloid Evolvability. J Alzheimers Dis. 2019; 68(2):473-481. Takamatsu Y, Ho G, Waragai M, Wada R, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 30741673.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    52. Remembering Robert D. Terry at a Time of Change in the World of Alzheimer's Disease. J Alzheimers Dis. 2019; 70(3):621-628. Terry N, Masliah A, Overk C, Masliah E. PMID: 31282421.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo. J Alzheimers Dis. 2019; 70(3):861-875. Simonovitch S, Schmukler E, Masliah E, Pinkas-Kramarski R, Michaelson DM. PMID: 31306119.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    54. Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease. J Parkinsons Dis. 2019; 9(4):793-802. Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Waragai M, Masliah E. PMID: 31524179.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    55. Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies. Sci Rep. 2018 12 27; 8(1):18083. Hassen GW, Kesner L, Stracher A, Shulman A, Rockenstein E, Mante M, Adame A, Overk C, Rissman RA, Masliah E. PMID: 30591714.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    56. Alterations in brain TREM2 and Amyloid-ß levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy. J Neurochem. 2018 12; 147(6):784-802. Fields JA, Spencer B, Swinton M, Qvale EM, Marquine MJ, Alexeeva A, Gough S, Soontornniyomkij B, Valera E, Masliah E, Achim CL, Desplats P. PMID: 30152135.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    57. Motor and Nonmotor Symptoms of Parkinson's Disease: Antagonistic Pleiotropy Phenomena Derived from a-Synuclein Evolvability? Parkinsons Dis. 2018; 2018:5789424. Takamatsu Y, Fujita M, Ho GJ, Wada R, Sugama S, Takenouchi T, Waragai M, Masliah E, Hashimoto M. PMID: 30595837.
      View in: PubMed   Mentions:
    58. The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease. Sci Rep. 2018 11 01; 8(1):16165. Price DL, Koike MA, Khan A, Wrasidlo W, Rockenstein E, Masliah E, Bonhaus D. PMID: 30385782.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    59. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiol Aging. 2019 03; 75:223.e1-223.e10. Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, Ansorge O, Clarimon J, Lleo A, Morenas-Rodriguez E, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Serrano GE, Beach TG, Lesage S, Galasko D, Masliah E, Santana I, Pastor P, Diez-Fairen M, Aguilar M, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Pickering-Brown S, Mann D, Halliday GM, Hardy J, Trojanowski JQ, Dickson DW, Singleton A, Stone DJ, Guerreiro R, Bras J. PMID: 30448004.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    60. A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder. Neurocase. 2018 08; 24(4):213-219. Hellmuth J, Milanini B, Masliah E, Tartaglia MC, Dunlop MB, Moore DJ, Javandel S, DeVaughn S, Valcour V. PMID: 30304986.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    61. T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation. Traffic. 2018 11; 19(11):840-853. Chen XQ, Fang F, Florio JB, Rockenstein E, Masliah E, Mobley WC, Rissman RA, Wu C. PMID: 30120810.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    62. LRRK2 kinase regulates a-synuclein propagation via RAB35 phosphorylation. Nat Commun. 2018 08 27; 9(1):3465. Bae EJ, Kim DK, Kim C, Mante M, Adame A, Rockenstein E, Ulusoy A, Klinkenberg M, Jeong GR, Bae JR, Lee C, Lee HJ, Lee BD, Di Monte DA, Masliah E, Lee SJ. PMID: 30150626.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    63. Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating a-synuclein transmission and neuroinflammation. Mol Neurodegener. 2018 08 09; 13(1):43. Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E. PMID: 30092810.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    64. a-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7813-7818. Prots I, Grosch J, Brazdis RM, Simmnacher K, Veber V, Havlicek S, Hannappel C, Krach F, Krumbiegel M, Schütz O, Reis A, Wrasidlo W, Galasko DR, Groemer TW, Masliah E, Schlötzer-Schrehardt U, Xiang W, Winkler J, Winner B. PMID: 29991596.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    65. Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders. Acta Neuropathol. 2018 07; 136(1):69-87. Spencer B, Brüschweiler S, Sealey-Cardona M, Rockenstein E, Adame A, Florio J, Mante M, Trinh I, Rissman RA, Konrat R, Masliah E. PMID: 29934874.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    66. Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS. PLoS One. 2018; 13(5):e0196949. González RG, Fell R, He J, Campbell J, Burdo TH, Autissier P, Annamalai L, Taheri F, Parker T, Lifson JD, Halpern EF, Vangel M, Masliah E, Westmoreland SV, Williams KC, Ratai EM. PMID: 29750804.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    67. Dual-therapy strategy for modification of adiponectin receptor signaling in aging-associated chronic diseases. Drug Discov Today. 2018 06; 23(6):1305-1311. Waragai M, Ho G, Takamatsu Y, Shimizu Y, Sugino H, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 29747002.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    68. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-ß plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037. Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Roßner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. PMID: 29630865.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    69. GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice. Sci Rep. 2018 04 03; 8(1):5460. Chen C, Li X, Ge G, Liu J, Biju KC, Laing SD, Qian Y, Ballard C, He Z, Masliah E, Clark RA, O'Connor JC, Li S. PMID: 29615705.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    70. NIA commentary on the NIA-AA Research Framework: Towards a biological definition of Alzheimer's disease. Alzheimers Dement. 2018 04; 14(4):576-578. Silverberg N, Elliott C, Ryan L, Masliah E, Hodes R. PMID: 29653608.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    71. SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy. J Neurosci. 2018 04 11; 38(15):3680-3688. Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L. PMID: 29540553.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    72. APOE DNA methylation is altered in Lewy body dementia. Alzheimers Dement. 2018 07; 14(7):889-894. Tulloch J, Leong L, Chen S, Keene CD, Millard SP, Shutes-David A, Lopez OL, Kofler J, Kaye JA, Woltjer R, Nelson PT, Neltner JH, Jicha GA, Galasko D, Masliah E, Leverenz JB, Yu CE, Tsuang D. PMID: 29544979.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    73. Exacerbation of sensorimotor dysfunction in mice deficient in Atp13a2 and overexpressing human wildtype alpha-synuclein. Behav Brain Res. 2018 05 02; 343:41-49. Dirr ER, Ekhator OR, Blackwood R, Holden JG, Masliah E, Schultheis PJ, Fleming SM. PMID: 29407413.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    74. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy. 2018; 14(1):98-119. Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Buzás EI, Schlötzer-Schrehardt U, Marcus K, Xiang W, Lie DC, Vekrellis K, Masliah E, Winkler J, Klucken J. PMID: 29198173.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    75. A refined concept: a-synuclein dysregulation disease. Neurochem Int. 2018 10; 119:84-96. Mochizuki H, Choong CJ, Masliah E. PMID: 29305061.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    76. Evolvability of Amyloidogenic Proteins in Human Brain. J Alzheimers Dis. 2018; 62(1):73-83. Hashimoto M, Ho G, Sugama S, Takamatsu Y, Shimizu Y, Takenouchi T, Waragai M, Masliah E. PMID: 29439348.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    77. Dale Schenk One Year Anniversary: Fighting to Preserve the Memories. J Alzheimers Dis. 2018; 62(1):1-13. Overk C, Masliah E. PMID: 29439357.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates. J Parkinsons Dis. 2018; 8(3):405-408. Hashimoto M, Ho G, Takamatsu Y, Shimizu Y, Sugama S, Takenouchi T, Waragai M, Masliah E. PMID: 30010144.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    79. Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability. J Huntingtons Dis. 2018; 7(4):297-307. Hashimoto M, Ho G, Takamatsu Y, Wada R, Sugama S, Takenouchi T, Masliah E, Waragai M. PMID: 30372687.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    80. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. J Alzheimers Dis. 2018; 61(3):1201-1219. Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA. PMID: 29332037.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    81. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. Lancet Neurol. 2018 01; 17(1):64-74. Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, Lleo A, Morenas-Rodriguez E, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Serrano GE, Beach TG, Lesage S, Galasko D, Masliah E, Santana I, Pastor P, Diez-Fairen M, Aguilar M, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Pickering-Brown S, Mann D, Halliday GM, Hardy J, Trojanowski JQ, Dickson DW, Singleton A, Stone DJ, Bras J. PMID: 29263008.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    82. Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies. J Neurosci. 2018 01 24; 38(4):1000-1014. Rockenstein E, Ostroff G, Dikengil F, Rus F, Mante M, Florio J, Adame A, Trinh I, Kim C, Overk C, Masliah E, Rissman RA. PMID: 29246926.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    83. Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting. Neurology. 2018 01 09; 90(2):74-82. Walsh RR, Krismer F, Galpern WR, Wenning GK, Low PA, Halliday G, Koroshetz WJ, Holton J, Quinn NP, Rascol O, Shaw LM, Eidelberg D, Bower P, Cummings JL, Abler V, Biedenharn J, Bitan G, Brooks DJ, Brundin P, Fernandez H, Fortier P, Freeman R, Gasser T, Hewitt A, Höglinger GU, Huentelman MJ, Jensen PH, Jeromin A, Kang UJ, Kaufmann H, Kellerman L, Khurana V, Klockgether T, Kim WS, Langer C, LeWitt P, Masliah E, Meissner W, Melki R, Ostrowitzki S, Piantadosi S, Poewe W, Robertson D, Roemer C, Schenk D, Schlossmacher M, Schmahmann JD, Seppi K, Shih L, Siderowf A, Stebbins GT, Stefanova N, Tsuji S, Sutton S, Zhang J. PMID: 29237794.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. PPARd activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Sci Transl Med. 2017 Dec 06; 9(419). Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, Ross CA, Masliah E, Evans RM, La Spada AR. PMID: 29212711.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    85. Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. Cell Rep. 2017 Nov 28; 21(9):2614-2627. Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR. PMID: 29186695.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    86. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nat Commun. 2017 11 14; 8(1):1488. Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, Huang X, Sultan A, McKercher SR, Ambasudhan R, Xu H, Wang Y, Geschwind DH, Roberts AJ, Terskikh AV, Rissman RA, Masliah E, Lipton SA, Nakanishi N. PMID: 29133852.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    87. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating ?-secretase activity. Nat Commun. 2017 11 13; 8(1):1472. Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. PMID: 29133892.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    88. The neuropathology of multiple system atrophy and its therapeutic implications. Auton Neurosci. 2018 05; 211:1-6. Valera E, Masliah E. PMID: 29169744.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    89. Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice. Brain Struct Funct. 2018 Apr; 223(3):1357-1368. Regensburger M, Schreglmann SR, Stoll S, Rockenstein E, Loskarn S, Xiang W, Masliah E, Winner B. PMID: 29124353.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    90. SORLA attenuates EphA4 signaling and amyloid ß-induced neurodegeneration. J Exp Med. 2017 Dec 04; 214(12):3669-3685. Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. PMID: 29114064.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    91. Multiple system atrophy: experimental models and reality. Acta Neuropathol. 2018 01; 135(1):33-47. Overk C, Rockenstein E, Valera E, Stefanova N, Wenning G, Masliah E. PMID: 29058121.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    92. MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Front Mol Neurosci. 2017; 10:329. Valera E, Spencer B, Mott J, Trejo M, Adame A, Mante M, Rockenstein E, Troncoso JC, Beach TG, Masliah E, Desplats P. PMID: 29089869.
      View in: PubMed   Mentions:
    93. Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. Sci Rep. 2017 08 21; 7(1):9008. Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E. PMID: 28827536.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    94. MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency. Neurobiol Aging. 2017 11; 59:156-170. Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. PMID: 28870518.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    95. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, et al. PMID: 28714976.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansCells
    96. Importance of adiponectin activity in the pathogenesis of Alzheimer's disease. Ann Clin Transl Neurol. 2017 08; 4(8):591-600. Waragai M, Ho G, Takamatsu Y, Sekiyama K, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 28812049.
      View in: PubMed   Mentions: 9     Fields:    
    97. Increased BACE1 activity inhibits peripheral nerve regeneration after injury. Neurobiol Dis. 2017 Oct; 106:147-157. Tallon C, Rockenstein E, Masliah E, Farah MH. PMID: 28687442.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    98. Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease. Sci Rep. 2017 06 20; 7(1):3868. Fang F, Yang W, Florio JB, Rockenstein E, Spencer B, Orain XM, Dong SX, Li H, Chen X, Sung K, Rissman RA, Masliah E, Ding J, Wu C. PMID: 28634349.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    99. Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation. Neurobiol Dis. 2017 Oct; 106:222-234. Reilly P, Winston CN, Baron KR, Trejo M, Rockenstein EM, Akers JC, Kfoury N, Diamond M, Masliah E, Rissman RA, Yuan SH. PMID: 28610892.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    100. Brain-derived exosomes from dementia with Lewy bodies propagate a-synuclein pathology. Acta Neuropathol Commun. 2017 06 09; 5(1):46. Ngolab J, Trinh I, Rockenstein E, Mante M, Florio J, Trejo M, Masliah D, Adame A, Masliah E, Rissman RA. PMID: 28599681.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    101. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. 2017 Jul 04; 89(1):88-100. McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. PMID: 28592453.
      View in: PubMed   Mentions: 356     Fields:    Translation:Humans
    102. Differential effects of immunotherapy with antibodies targeting a-synuclein oligomers and fibrils in a transgenic model of synucleinopathy. Neurobiol Dis. 2017 Aug; 104:85-96. El-Agnaf O, Overk C, Rockenstein E, Mante M, Florio J, Adame A, Vaikath N, Majbour N, Lee SJ, Kim C, Masliah E, Rissman RA. PMID: 28476636.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    103. Gene expression patterns associated with neurological disease in human HIV infection. PLoS One. 2017; 12(4):e0175316. Sanna PP, Repunte-Canonigo V, Masliah E, Lefebvre C. PMID: 28445538.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    104. Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection. AIDS. 2017 04 24; 31(7):973-979. Bryant AK, Moore DJ, Burdo TH, Lakritz JR, Gouaux B, Soontornniyomkij V, Achim CL, Masliah E, Grant I, Levine AJ, Ellis RJ. PMID: 28244955.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    105. Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):E3679-E3688. Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou D, Wrasidlo W, Bohl D, Stellas D, Politis PK, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E, Matsas R. PMID: 28416701.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    106. CNS findings in chronic fatigue syndrome and a neuropathological case report. J Investig Med. 2017 08; 65(6):974-983. Ferrero K, Silver M, Cocchetto A, Masliah E, Langford D. PMID: 28386034.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    107. Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies. Neural Plast. 2017; 2017:3851262. Kohl Z, Schlachetzki JC, Feldewerth J, Hornauer P, Münch M, Adame A, Riemenschneider MJ, Winkler J, Masliah E. PMID: 28409032.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    108. HIV Tat protein and amyloid-ß peptide form multifibrillar structures that cause neurotoxicity. Nat Struct Mol Biol. 2017 04; 24(4):379-386. Hategan A, Bianchet MA, Steiner J, Karnaukhova E, Masliah E, Fields A, Lee MH, Dickens AM, Haughey N, Dimitriadis EK, Nath A. PMID: 28218748.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    109. Early start of progressive motor deficits in Line 61 a-synuclein transgenic mice. BMC Neurosci. 2017 01 31; 18(1):22. Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, Niederkofler V, Rockenstein E, Masliah E, Roemer H, Hutter-Paier B. PMID: 28143405.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    110. Perspective on the calcium dyshomeostasis hypothesis in the pathogenesis of selective neuronal degeneration in animal models of Alzheimer's disease. Alzheimers Dement. 2017 02; 13(2):183-185. Overk C, Masliah E. PMID: 28130011.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    111. The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration. J Neurovirol. 2017 04; 23(2):290-303. Fields JA, Metcalf J, Overk C, Adame A, Spencer B, Wrasidlo W, Florio J, Rockenstein E, He JJ, Masliah E. PMID: 28105557.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    112. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017 03 02; 20(3):345-359.e5. Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM. PMID: 28111199.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    113. Anti-a-synuclein immunotherapy reduces a-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy. Acta Neuropathol Commun. 2017 01 13; 5(1):7. Spencer B, Valera E, Rockenstein E, Overk C, Mante M, Adame A, Zago W, Seubert P, Barbour R, Schenk D, Games D, Rissman RA, Masliah E. PMID: 28086964.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    114. Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy. Acta Neuropathol Commun. 2017 01 05; 5(1):2. Valera E, Spencer B, Fields JA, Trinh I, Adame A, Mante M, Rockenstein E, Desplats P, Masliah E. PMID: 28057080.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    115. Hippocampal a-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 02 15; 37(7):1675-1684. Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH. PMID: 28039370.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    116. Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models. Cell Death Dis. 2016 12 01; 7(12):e2499. Lipton SA, Rezaie T, Nutter A, Lopez KM, Parker J, Kosaka K, Satoh T, McKercher SR, Masliah E, Nakanishi N. PMID: 27906174.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    117. Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1. Alzheimers Dement. 2017 Jun; 13(6):689-700. Cronin P, McCarthy MJ, Lim ASP, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P. PMID: 27883893.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    118. Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):E7564-E7571. Sunico CR, Sultan A, Nakamura T, Dolatabadi N, Parker J, Shan B, Han X, Yates JR, Masliah E, Ambasudhan R, Nakanishi N, Lipton SA. PMID: 27821734.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    119. Preclinical Assessment of Young Blood Plasma for Alzheimer Disease. JAMA Neurol. 2016 Nov 01; 73(11):1325-1333. Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. PMID: 27598869.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    120. Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans. Sci Rep. 2016 10 06; 6:34477. Chen SG, Stribinskis V, Rane MJ, Demuth DR, Gozal E, Roberts AM, Jagadapillai R, Liu R, Choe K, Shivakumar B, Son F, Jin S, Kerber R, Adame A, Masliah E, Friedland RP. PMID: 27708338.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    121. The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philos Trans R Soc Lond B Biol Sci. 2016 10 05; 371(1705). Uhlirova H, Kiliç K, Tian P, Sakadžic S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A. PMID: 27574309.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    122. A de novo compound targeting a-synuclein improves deficits in models of Parkinson's disease. Brain. 2016 12; 139(Pt 12):3217-3236. Wrasidlo W, Tsigelny IF, Price DL, Dutta G, Rockenstein E, Schwarz TC, Ledolter K, Bonhaus D, Paulino A, Eleuteri S, Skjevik ÅA, Kouznetsova VL, Spencer B, Desplats P, Gonzalez-Ruelas T, Trejo-Morales M, Overk CR, Winter S, Zhu C, Chesselet MF, Meier D, Moessler H, Konrat R, Masliah E. PMID: 27679481.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    123. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiol Aging. 2017 01; 49:214.e13-214.e15. Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, Holstege H, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Trojanowski JQ, Serrano GE, Beach TG, Clarimon J, Lleó A, Morenas-Rodríguez E, Lesage S, Galasko D, Masliah E, Santana I, Diez M, Pastor P, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Stone DJ, Pickering-Brown S, Mann D, Dickson DW, Halliday GM, Singleton A, Guerreiro R, Bras J. PMID: 27666590.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    124. Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model. Sci Rep. 2016 08 25; 6:31692. Xu J, de Winter F, Farrokhi C, Rockenstein E, Mante M, Adame A, Cook J, Jin X, Masliah E, Lee KF. PMID: 27558862.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    125. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. J Clin Invest. 2016 09 01; 126(9):3585-97. Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. PMID: 27525439.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    126. Exposure to bacterial endotoxin generates a distinct strain of a-synuclein fibril. Sci Rep. 2016 08 04; 6:30891. Kim C, Lv G, Lee JS, Jung BC, Masuda-Suzukake M, Hong CS, Valera E, Lee HJ, Paik SR, Hasegawa M, Masliah E, Eliezer D, Lee SJ. PMID: 27488222.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    127. Reducing Endogenous a-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model. J Neurosci. 2016 07 27; 36(30):7971-84. Spencer B, Desplats PA, Overk CR, Valera-Martin E, Rissman RA, Wu C, Mante M, Adame A, Florio J, Rockenstein E, Masliah E. PMID: 27466341.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    128. Five and four dimensional experiments for robust backbone resonance assignment of large intrinsically disordered proteins: application to Tau3x protein. J Biomol NMR. 2016 08; 65(3-4):193-203. Zerko S, Byrski P, Wlodarczyk-Pruszynski P, Górka M, Ledolter K, Masliah E, Konrat R, Kozminski W. PMID: 27430223.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    129. Longitudinal live imaging of retinal a-synuclein::GFP deposits in a transgenic mouse model of Parkinson's Disease/Dementia with Lewy Bodies. Sci Rep. 2016 07 08; 6:29523. Price DL, Rockenstein E, Mante M, Adame A, Overk C, Spencer B, Duong-Polk KX, Bonhaus D, Lindsey J, Masliah E. PMID: 27389831.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    130. Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an a-Synuclein Transgenic Model of Parkinson's Disease. J Exp Neurosci. 2015; 9(Suppl 2):131-40. Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Moessler H, Masliah E. PMID: 27429559.
      View in: PubMed   Mentions:
    131. Small molecule NPT-440-1 inhibits ionic flux through Aß1-42 pores: Implications for Alzheimer's disease therapeutics. Nanomedicine. 2016 11; 12(8):2331-2340. Gillman AL, Lee J, Ramachandran S, Capone R, Gonzalez T, Wrasidlo W, Masliah E, Lal R. PMID: 27335341.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    132. a-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease. Ann Clin Transl Neurol. 2016 08; 3(8):588-606. Spencer B, Williams S, Rockenstein E, Valera E, Xin W, Mante M, Florio J, Adame A, Masliah E, Sierks MR. PMID: 27606342.
      View in: PubMed   Mentions: 15     Fields:    
    133. Non-cell-autonomous Neurotoxicity of a-synuclein Through Microglial Toll-like Receptor 2. Exp Neurobiol. 2016 Jun; 25(3):113-9. Kim C, Lee HJ, Masliah E, Lee SJ. PMID: 27358579.
      View in: PubMed   Mentions:
    134. Cell type specificity of neurovascular coupling in cerebral cortex. Elife. 2016 05 31; 5. Uhlirova H, Kiliç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžic S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DA, Kleinfeld D, Buxton RB, Einevoll GT, Dale AM, Devor A. PMID: 27244241.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    135. Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum. J Neuropathol Exp Neurol. 2016 07; 75(7):663-72. Barca E, Kleiner G, Tang G, Ziosi M, Tadesse S, Masliah E, Louis ED, Faust P, Kang UJ, Torres J, Cortes EP, Vonsattel JP, Kuo SH, Quinzii CM. PMID: 27235405.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    136. Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity. J Neuroinflammation. 2016 05 24; 13(1):120. Fields JA, Overk C, Adame A, Florio J, Mante M, Pineda A, Desplats P, Rockenstein E, Achim C, Masliah E. PMID: 27220536.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    137. Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 05 23; 11(1):42. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. PMID: 27216421.
      View in: PubMed   Mentions: 1     Fields:    
    138. Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile. Alzheimers Dement (Amst). 2016; 3:63-72. Winston CN, Goetzl EJ, Akers JC, Carter BS, Rockenstein EM, Galasko D, Masliah E, Rissman RA. PMID: 27408937.
      View in: PubMed   Mentions:
    139. Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. HIV AIDS (Auckl). 2016; 8:93-9. Bharti AR, Woods SP, Ellis RJ, Cherner M, Rosario D, Potter M, Heaton RK, Everall IP, Masliah E, Grant I, Letendre SL. PMID: 27199571.
      View in: PubMed   Mentions:
    140. Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease. Hum Mol Genet. 2016 07 01; 25(13):2645-2660. Rockenstein E, Clarke J, Viel C, Panarello N, Treleaven CM, Kim C, Spencer B, Adame A, Park H, Dodge JC, Cheng SH, Shihabuddin LS, Masliah E, Sardi SP. PMID: 27126635.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    141. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016 04 26; 11:31. Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. PMID: 27112350.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    142. Lifetime methamphetamine dependence is associated with cerebral microgliosis in HIV-1-infected adults. J Neurovirol. 2016 10; 22(5):650-660. Soontornniyomkij V, Umlauf A, Soontornniyomkij B, Batki IB, Moore DJ, Masliah E, Achim CL. PMID: 27098516.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    143. a-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathol. 2016 07; 132(1):59-75. Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. PMID: 27059609.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    144. Possible Involvement of Adiponectin, the Anti-Diabetes Molecule, in the Pathogenesis of Alzheimer's Disease. J Alzheimers Dis. 2016 04 08; 52(4):1453-9. Waragai M, Adame A, Trinh I, Sekiyama K, Takamatsu Y, Une K, Masliah E, Hashimoto M. PMID: 27079710.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    145. Synergistic Increase of Serum BDNF in Alzheimer Patients Treated with Cerebrolysin and Donepezil: Association with Cognitive Improvement in ApoE4 Cases. Int J Neuropsychopharmacol. 2016 06; 19(6). Alvarez XA, Alvarez I, Iglesias O, Crespo I, Figueroa J, Aleixandre M, Linares C, Granizo E, Garcia-Fantini M, Marey J, Masliah E, Winter S, Muresanu D, Moessler H. PMID: 27207906.
      View in: PubMed   Mentions: 3     Fields:    
    146. An Anti-ß-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome. PLoS One. 2016; 11(3):e0152471. Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, Reis P, Granet A, Mlaki D, Lopez-Deber MP, Do L, Singhal N, Masliah E, Pearn ML, Pfeifer A, Muhs A, Mobley WC. PMID: 27023444.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCellsPHPublic Health
    147. The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons. Neurotox Res. 2016 May; 29(4):583-593. Avdoshina V, Fields JA, Castellano P, Dedoni S, Palchik G, Trejo M, Adame A, Rockenstein E, Eugenin E, Masliah E, Mocchetti I. PMID: 26936603.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    148. Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice. . 2016 04; 17(4):530-51. Maeda S, Djukic B, Taneja P, Yu GQ, Lo I, Davis A, Craft R, Guo W, Wang X, Kim D, Ponnusamy R, Gill TM, Masliah E, Mucke L. PMID: 26931567.
      View in: PubMed   Mentions:
    149. Therapeutic approaches in Parkinson's disease and related disorders. J Neurochem. 2016 10; 139 Suppl 1:346-352. Valera E, Masliah E. PMID: 26749150.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    150. Induction of de novo a-synuclein fibrillization in a neuronal model for Parkinson's disease. Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7):E912-21. Fares MB, Maco B, Oueslati A, Rockenstein E, Ninkina N, Buchman VL, Masliah E, Lashuel HA. PMID: 26839406.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    151. Review: Novel treatment strategies targeting alpha-synuclein in multiple system atrophy as a model of synucleinopathy. Neuropathol Appl Neurobiol. 2016 Feb; 42(1):95-106. Valera E, Monzio Compagnoni G, Masliah E. PMID: 26924723.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    152. Expression of gp120 in mice evokes anxiety behavior: Co-occurrence with increased dendritic spines and brain-derived neurotrophic factor in the amygdala. Brain Behav Immun. 2016 May; 54:170-177. Bachis A, Forcelli P, Masliah E, Campbell L, Mocchetti I. PMID: 26845379.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    153. Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum. Sci Rep. 2016 Feb 01; 6:20201. Chen AI, Zang K, Masliah E, Reichardt LF. PMID: 26830657.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    154. Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability. Alzheimers Dement. 2016 06; 12(6):633-44. de Wilde MC, Overk CR, Sijben JW, Masliah E. PMID: 26776762.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    155. a-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease. Hum Mol Genet. 2016 Mar 15; 25(6):1100-15. Spencer B, Kim C, Gonzalez T, Bisquertt A, Patrick C, Rockenstein E, Adame A, Lee SJ, Desplats P, Masliah E. PMID: 26740557.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    156. Immunotherapeutic Approaches Targeting Amyloid-ß, a-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders. Neurotherapeutics. 2016 Jan; 13(1):179-89. Valera E, Spencer B, Masliah E. PMID: 26494242.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    157. Impaired Autophagy in APOE4 Astrocytes. J Alzheimers Dis. 2016; 51(3):915-27. Simonovitch S, Schmukler E, Bespalko A, Iram T, Frenkel D, Holtzman DM, Masliah E, Michaelson DM, Pinkas-Kramarski R. PMID: 26923027.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    158. Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders. J Neurovirol. 2016 06; 22(3):366-75. Levine AJ, Quach A, Moore DJ, Achim CL, Soontornniyomkij V, Masliah E, Singer EJ, Gelman B, Nemanim N, Horvath S. PMID: 26689571.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    159. Hypoestoxide reduces neuroinflammation and a-synuclein accumulation in a mouse model of Parkinson's disease. J Neuroinflammation. 2015 Dec 18; 12:236. Kim C, Ojo-Amaize E, Spencer B, Rockenstein E, Mante M, Desplats P, Wrasidlo W, Adame A, Nchekwube E, Oyemade O, Okogun J, Chan M, Cottam H, Masliah E. PMID: 26683203.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    160. PPAR-d is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Nat Med. 2016 Jan; 22(1):37-45. Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR. PMID: 26642438.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    161. Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. J Neurovirol. 2016 08; 22(4):431-41. Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ. PMID: 26637429.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    162. Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease. J Biol Chem. 2016 Jan 22; 291(4):1905-20. Spencer B, Potkar R, Metcalf J, Thrin I, Adame A, Rockenstein E, Masliah E. PMID: 26620558.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    163. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. Nat Commun. 2015 Nov 30; 6:8897. Suberbielle E, Djukic B, Evans M, Kim DH, Taneja P, Wang X, Finucane M, Knox J, Ho K, Devidze N, Masliah E, Mucke L. PMID: 26615780.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    164. Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. BMC Neurosci. 2015 Nov 26; 16:85. Rockenstein E, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. PMID: 26611895.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    165. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 Feb; 86:154-69. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy AN, Ellis RJ, Letendre S, Grant I, Masliah E. PMID: 26611103.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    166. Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease. Alzheimers Dement. 2016 05; 12(5):527-37. Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA. PMID: 26555315.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    167. Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC a-synuclein transgenic rat model of Parkinson's disease. Neurobiol Dis. 2016 Jan; 85:206-217. Kohl Z, Ben Abdallah N, Vogelgsang J, Tischer L, Deusser J, Amato D, Anderson S, Müller CP, Riess O, Masliah E, Nuber S, Winkler J. PMID: 26523794.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    168. NEDD4-mediated HSF1 degradation underlies a-synucleinopathy. Hum Mol Genet. 2016 Jan 15; 25(2):211-22. Kim E, Wang B, Sastry N, Masliah E, Nelson PT, Cai H, Liao FF. PMID: 26503960.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    169. Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy. Cell Rep. 2015 Oct 27; 13(4):771-782. Kim C, Rockenstein E, Spencer B, Kim HK, Adame A, Trejo M, Stafa K, Lee HJ, Lee SJ, Masliah E. PMID: 26489461.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    170. Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism. Stem Cell Reports. 2015 Nov 10; 5(5):791-804. Goldberg NRS, Caesar J, Park A, Sedgh S, Finogenov G, Masliah E, Davis J, Blurton-Jones M. PMID: 26489892.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    171. Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease. JAMA Neurol. 2015 Oct; 72(10):1139-47. Tuszynski MH, Yang JH, Barba D, U HS, Bakay RA, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH. PMID: 26302439.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCellsCTClinical Trials
    172. Systemic Amyloid A Amyloidosis in Island Foxes (Urocyon littoralis): Severity and Risk Factors. Vet Pathol. 2016 May; 53(3):637-47. Gaffney PM, Witte C, Clifford DL, Imai DM, O'Brien TD, Trejo M, Liberta F, Annamalai K, Fändrich M, Masliah E, Munson L, Sigurdson CJ. PMID: 26419399.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    173. A brain-targeted, modified neurosin (kallikrein-6) reduces a-synuclein accumulation in a mouse model of multiple system atrophy. Mol Neurodegener. 2015 Sep 23; 10:48. Spencer B, Valera E, Rockenstein E, Trejo-Morales M, Adame A, Masliah E. PMID: 26394760.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    174. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015 Oct; 21(10):1154-62. Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. PMID: 26390242.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    175. Combination therapies: The next logical Step for the treatment of synucleinopathies? Mov Disord. 2016 Feb; 31(2):225-34. Valera E, Masliah E. PMID: 26388203.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    176. Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model. J Mol Neurosci. 2016 Jan; 58(1):59-65. Nakanishi N, Kang YJ, Tu S, McKercher SR, Masliah E, Lipton SA. PMID: 26374431.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    177. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 2015 Sep 02; 87(5):963-75. Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, St George-Hyslop P, Masliah E, Fraser P, Xu H. PMID: 26335643.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    178. Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506. Neuroscience. 2015 Dec 03; 310:549-60. Overk CR, Rockenstein E, Florio J, Cheng Q, Masliah E. PMID: 26341908.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    179. Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease. J Neurochem. 2015 Nov; 135(3):589-97. Deusser J, Schmidt S, Ettle B, Plötz S, Huber S, Müller CP, Masliah E, Winkler J, Kohl Z. PMID: 26201615.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    180. Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme. Br J Pharmacol. 2015 Oct; 172(19):4603-14. PMID: 24571443.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    181. Recognition memory span in autopsy-confirmed Dementia with Lewy Bodies and Alzheimer's Disease. Neuropsychologia. 2015 Aug; 75:548-55. Salmon DP, Heindel WC, Hamilton JM, Vincent Filoteo J, Cidambi V, Hansen LA, Masliah E, Galasko D. PMID: 26184443.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    182. Neurodegeneration: Aggregates feel the strain. Nature. 2015 Jun 18; 522(7556):296-7. Lee SJ, Masliah E. PMID: 26061764.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    183. Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease. J Neuroinflammation. 2015 May 14; 12:93. Valera E, Mante M, Anderson S, Rockenstein E, Masliah E. PMID: 25966683.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    184. The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice. PLoS One. 2015; 10(5):e0126261. Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B. PMID: 25961568.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    185. Neuro-peptide treatment with Cerebrolysin improves the survival of neural stem cell grafts in an APP transgenic model of Alzheimer disease. Stem Cell Res. 2015 Jul; 15(1):54-67. Rockenstein E, Desplats P, Ubhi K, Mante M, Florio J, Adame A, Winter S, Brandstaetter H, Meier D, Masliah E. PMID: 26209890.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    186. Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's disease. PLoS One. 2015; 10(4):e0122451. Dewji NN, Singer SJ, Masliah E, Rockenstein E, Kim M, Harber M, Horwood T. PMID: 25923432.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    187. A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies. PLoS One. 2015; 10(3):e0121570. Rockenstein E, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Bisquert A, Trejo-Morales M, Spencer B, Masliah E. PMID: 25803611.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    188. Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. Mol Neurodegener. 2015 Mar 19; 10:10. Mandler M, Valera E, Rockenstein E, Mante M, Weninger H, Patrick C, Adame A, Schmidhuber S, Santic R, Schneeberger A, Schmidt W, Mattner F, Masliah E. PMID: 25886309.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCellsPHPublic Health
    189. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathol. 2015 May; 129(5):757-62. PMID: 25778618.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    190. Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid. J Neurochem. 2015 Jun; 133(6):898-908. Zhang D, Lee B, Nutter A, Song P, Dolatabadi N, Parker J, Sanz-Blasco S, Newmeyer T, Ambasudhan R, McKercher SR, Masliah E, Lipton SA. PMID: 25692407.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    191. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015 Apr; 2(4):417-26. Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. PMID: 25909086.
      View in: PubMed   Mentions: 27     Fields:    
    192. Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. J Neurosci. 2015 Feb 11; 35(6):2358-71. Dubal DB, Zhu L, Sanchez PE, Worden K, Broestl L, Johnson E, Ho K, Yu GQ, Kim D, Betourne A, Kuro-O M, Masliah E, Abraham CR, Mucke L. PMID: 25673831.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    193. Parkinson disease mutant E46K enhances a-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. J Biol Chem. 2015 Apr 10; 290(15):9412-27. PMID: 25657004.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    194. HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. J Neurosci. 2015 Feb 04; 35(5):1921-38. Fields J, Dumaop W, Eleuteri S, Elueteri S, Campos S, Serger E, Trejo M, Kosberg K, Adame A, Spencer B, Rockenstein E, He JJ, Masliah E. PMID: 25653352.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    195. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25531812.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    196. Antiretroviral therapy reduces neurodegeneration in HIV infection. AIDS. 2015 Jan 28; 29(3):323-30. Bryant AK, Ellis RJ, Umlauf A, Gouaux B, Soontornniyomkij V, Letendre SL, Achim CL, Masliah E, Grant I, Moore DJ. PMID: 25686681.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    197. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015 Mar; 18(3):423-34. Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L. PMID: 25622143.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    198. Molecular determinants of a-synuclein mutants' oligomerization and membrane interactions. ACS Chem Neurosci. 2015 Mar 18; 6(3):403-16. Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Overk C, Gonzalez T, Trejo M, Spencer B, Kosberg K, Masliah E. PMID: 25561023.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    199. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. J Alzheimers Dis. 2015; 43(3):967-76. PMID: 25125464.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    200. Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease. J Parkinsons Dis. 2015; 5(3):669-680. Magen I, Torres ER, Dinh D, Chung A, Masliah E, Chesselet MF. PMID: 25588356.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    201. Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer's Disease. Methods Mol Biol. 2015; 1324:331-7. Masliah E, Spencer B. PMID: 26202279.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    202. Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. Curr HIV Res. 2015; 13(1):43-54. Fields JA, Dumaop W, Crews L, Adame A, Spencer B, Metcalf J, He J, Rockenstein E, Masliah E. PMID: 25760044.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    203. Autophagy in Alzheimer's disease. Rev Neurosci. 2015; 26(4):385-95. Zare-Shahabadi A, Masliah E, Johnson GV, Rezaei N. PMID: 25870960.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    204. Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on a-synuclein. Neuron. 2015 Jan 07; 85(1):76-87. PMID: 25533483.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    205. Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders. Br J Pharmacol. 2014 Dec; 171(24):5757-73. PMID: 25117211.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    206. Proteomic analysis of highly prevalent amyloid A amyloidosis endemic to endangered island foxes. PLoS One. 2014; 9(11):e113765. Gaffney PM, Imai DM, Clifford DL, Ghassemian M, Sasik R, Chang AN, O'Brien TD, Coppinger J, Trejo M, Masliah E, Munson L, Sigurdson C. PMID: 25429466.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    207. Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats. FASEB J. 2015 Mar; 29(3):911-9. Gaffney PM, Barr B, Rowe JD, Bett C, Drygiannakis I, Giannitti F, Trejo M, Ghassemian M, Martin P, Masliah E, Sigurdson CJ. PMID: 25422367.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    208. Modulation of the maladaptive stress response to manage diseases of protein folding. PLoS Biol. 2014 Nov; 12(11):e1001998. Roth DM, Hutt DM, Tong J, Bouchecareilh M, Wang N, Seeley T, Dekkers JF, Beekman JM, Garza D, Drew L, Masliah E, Morimoto RI, Balch WE. PMID: 25406061.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    209. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25199842.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    210. Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes. Physiol Rep. 2014 Nov 01; 2(11). PMID: 25428949.
      View in: PubMed   Mentions: 2     Fields:    
    211. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014 Dec; 128(6):755-66. Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. PMID: 25348064.
      View in: PubMed   Mentions: 338     Fields:    Translation:Humans
    212. Neurogranin binds a-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease. Brain Res. 2014 Dec 03; 1591:102-10. PMID: 25446004.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    213. Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy. Cell Metab. 2014 Oct 07; 20(4):626-38. Dubinsky AN, Dastidar SG, Hsu CL, Zahra R, Djakovic SN, Duarte S, Esau CC, Spencer B, Ashe TD, Fischer KM, MacKenna DA, Sopher BL, Masliah E, Gaasterland T, Chau BN, Pereira de Almeida L, Morrison BE, La Spada AR. PMID: 25295787.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    214. Toward a unified therapeutics approach targeting putative amyloid-ß oligomer receptors. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13680-1. Overk CR, Masliah E. PMID: 25205809.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    215. Novel therapeutic strategy for neurodegeneration by blocking Aß seeding mediated aggregation in models of Alzheimer's disease. Neurobiol Dis. 2015 Feb; 74:144-57. PMID: 25173807.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    216. Glucocerebrosidase depletion enhances cell-to-cell transmission of a-synuclein. Nat Commun. 2014 Aug 26; 5:4755. PMID: 25156829.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    217. Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence. PLoS One. 2014; 9(7):e102555. PMID: 25054922.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    218. Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure. BMC Neurosci. 2014 Jul 21; 15:90. PMID: 25047000.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    219. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells. Mol Cell Neurosci. 2014 Sep; 62:68-78. PMID: 25019582.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    220. ESCRT-mediated uptake and degradation of brain-targeted a-synuclein single chain antibody attenuates neuronal degeneration in vivo. Mol Ther. 2014 Oct; 22(10):1753-67. PMID: 25008355.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    221. Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models. J Neurosci. 2014 Jul 09; 34(28):9441-54. PMID: 25009275.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimals
    222. Disease-Modifying Effect of Adiponectin in Model of a-Synucleinopathies. Ann Clin Transl Neurol. 2014 Jul 03; 1(7):479-489. PMID: 25126588.
      View in: PubMed   Mentions: 10     Fields:    
    223. Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. Mol Neurodegener. 2014 Jul 01; 9:26. PMID: 24980976.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    224. Transglutaminase 2 exacerbates a-synuclein toxicity in mice and yeast. FASEB J. 2014 Oct; 28(10):4280-91. PMID: 24970392.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    225. Silencing of murine transthyretin and retinol binding protein genes has distinct and shared behavioral and neuropathologic effects. Neuroscience. 2014 Sep 05; 275:352-64. PMID: 24956283.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    226. Immunotherapy for Alzheimer's disease: past, present and future. Front Aging Neurosci. 2014; 6:114. PMID: 24959143.
      View in: PubMed   Mentions:
    227. HIV protease inhibitor exposure predicts cerebral small vessel disease. AIDS. 2014 Jun 01; 28(9):1297-306. PMID: 24637542.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    228. Hippocampal neuronal cells that accumulate a-synuclein fragments are more vulnerable to Aß oligomer toxicity via mGluR5--implications for dementia with Lewy bodies. Mol Neurodegener. 2014 May 19; 9:18. PMID: 24885390.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    229. A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis. J Biol Chem. 2014 Jun 20; 289(25):17917-31. Spencer B, Verma I, Desplats P, Morvinski D, Rockenstein E, Adame A, Masliah E. PMID: 24825898.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    230. Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells. J Comp Neurol. 2014 Aug 15; 522(12):2845-56. Ambasudhan R, Dolatabadi N, Nutter A, Masliah E, Mckercher SR, Lipton SA. PMID: 24756727.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    231. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Res Ther. 2014 Apr 16; 5(2):46. PMID: 25022790.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    232. Accumulation of oligomer-prone a-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain. 2014 May; 137(Pt 5):1496-513. PMID: 24662516.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    233. Phospholipase D1 regulates autophagic flux and clearance of a-synuclein aggregates. Cell Death Differ. 2014 Jul; 21(7):1132-41. PMID: 24632948.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    234. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]aSyn transgenic mice. Hum Mol Genet. 2014 Aug 01; 23(15):3975-89. PMID: 24619358.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    235. a-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy. Neurobiol Aging. 2014 Oct; 35(10):2357-68. May VE, Ettle B, Poehler AM, Nuber S, Ubhi K, Rockenstein E, Winner B, Wegner M, Masliah E, Winkler J. PMID: 24698767.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    236. Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials. Acta Neuropathol. 2014; 127(6):861-79. PMID: 24525765.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    237. Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders. J Neuroimmune Pharmacol. 2014 Mar; 9(2):102-16. PMID: 24510686.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    238. Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD. Acta Neuropathol. 2014 Apr; 127(4):477-94. PMID: 24509835.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    239. Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease. Biochem Pharmacol. 2014 Apr 15; 88(4):508-16. PMID: 24462903.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    240. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Mar; 127(3):407-18. PMID: 24442578.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    241. c-Abl phosphorylates a-synuclein and regulates its degradation: implication for a-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. Hum Mol Genet. 2014 Jun 01; 23(11):2858-79. PMID: 24412932.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    242. Autophagy modulates SNCA/a-synuclein release, thereby generating a hostile microenvironment. Autophagy. 2014; 10(12):2171-92. PMID: 25484190.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    243. Apathy and APOE4 are associated with reduced BDNF levels in Alzheimer's disease. J Alzheimers Dis. 2014; 42(4):1347-55. PMID: 25024337.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    244. The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis. Br J Pharmacol. 2014 Jan; 171(2):468-79. PMID: 24148086.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    245. Structural diversity of Alzheimer's disease amyloid-ß dimers and their role in oligomerization and fibril formation. J Alzheimers Dis. 2014; 39(3):583-600. PMID: 24240640.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    246. Prodegenerative I?Ba expression in oligodendroglial a-synuclein models of multiple system atrophy. Neurobiol Dis. 2014 Mar; 63:171-83. Kragh CL, Gysbers AM, Rockenstein E, Murphy K, Halliday GM, Masliah E, Jensen PH. PMID: 24361600.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    247. Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy. Glia. 2014 Feb; 62(2):317-37. PMID: 24310907.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    248. Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. Eur J Neurosci. 2014 Mar; 39(6):1026-41. PMID: 24304186.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    249. De novo prion aggregates trigger autophagy in skeletal muscle. J Virol. 2014 Feb; 88(4):2071-82. PMID: 24307586.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    250. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Res. 2014 Jan; 24(1):126-9. PMID: 24296783.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    251. Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders. J Neuroimmune Pharmacol. 2013 Dec; 8(5):1197-209. PMID: 24292993.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    252. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1a transcription. Cell. 2013 Dec 05; 155(6):1351-64. PMID: 24290359.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansCells
    253. Chronic cerebrolysin administration attenuates neuronal abnormalities in the basolateral amygdala induced by neonatal ventral hippocampus lesion in the rat. Synapse. 2014 Jan; 68(1):31-8. PMID: 24123373.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    254. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 2013 Oct 16; 80(2):270-4. PMID: 24139032.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    255. Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice. J Neurosci. 2013 Sep 25; 33(39):15596-602. PMID: 24068826.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    256. Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases. PLoS One. 2013; 8(9):e75025. PMID: 24073234.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    257. Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. PLoS One. 2013; 8(9):e73956. PMID: 24023918.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    258. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron. 2013 Sep 04; 79(5):873-86. PMID: 24012002.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    259. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Mol Neurodegener. 2013 Aug 28; 8:29. PMID: 23985028.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    260. Herpes virus in Alzheimer's disease: relation to progression of the disease. Neurobiol Aging. 2014 Jan; 35(1):122-9. PMID: 23916950.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    261. Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes. Epigenetics. 2013 Oct; 8(10):1030-8. PMID: 23907097.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    262. Fatal pulmonary embolism update: 10 years of autopsy experience at an academic medical center. JRSM Short Rep. 2013; 4(9):2042533313489824. PMID: 24040503.
      View in: PubMed   Mentions:
    263. Impaired baroreflex function in mice overexpressing alpha-synuclein. Front Neurol. 2013; 4:103. PMID: 23888153.
      View in: PubMed   Mentions:
    264. Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice. Neurobiol Dis. 2013 Nov; 59:38-51. PMID: 23867236.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    265. Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: beyond cognition. Alzheimers Dement. 2014 Mar; 10(2):171-8. PMID: 23850331.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    266. Dual effects of ß-synuclein on the pathogenesis of Parkinson disease. Ann Neurol. 2013 Aug; 74(2):306. PMID: 23836414.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    267. Aß induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):E2518-27. PMID: 23776240.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    268. FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell. 2013 Jun; 12(3):518-22. PMID: 23551888.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    269. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J Neurosci. 2013 May 08; 33(19):8411-22. PMID: 23658179.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    270. Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human a-synuclein. PLoS One. 2013; 8(5):e63557. PMID: 23667637.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    271. A blood-brain barrier (BBB) disrupter is also a potent a-synuclein (a-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD). J Biol Chem. 2013 Jun 14; 288(24):17579-88. PMID: 23637226.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    272. TOM40 mediates mitochondrial dysfunction induced by a-synuclein accumulation in Parkinson's disease. PLoS One. 2013; 8(4):e62277. PMID: 23626796.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    273. Defining the conformational features of anchorless, poorly neuroinvasive prions. PLoS Pathog. 2013; 9(4):e1003280. PMID: 23637596.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    274. Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort. . 2013 Apr 15; 62(5):487-95. PMID: 23242157.
      View in: PubMed   Mentions:
    275. Spongiform change in dementia with Lewy bodies and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):157-61. PMID: 22546782.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    276. Molecular and pathologic insights from latent HIV-1 infection in the human brain. Neurology. 2013 Apr 09; 80(15):1415-23. PMID: 23486877.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    277. Neuropsychiatric features of frontal lobe dysfunction in autopsy-confirmed patients with lewy bodies and "pure" Alzheimer disease. Am J Geriatr Psychiatry. 2013 Jun; 21(6):509-19. PMID: 23567425.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    278. Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3609-14. PMID: 23401561.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    279. Mapping the subcellular distribution of a-synuclein in neurons using genetically encoded probes for correlated light and electron microscopy: implications for Parkinson's disease pathogenesis. J Neurosci. 2013 Feb 06; 33(6):2605-15. PMID: 23392688.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    280. Immunotherapy for neurodegenerative diseases: focus on a-synucleinopathies. Pharmacol Ther. 2013 Jun; 138(3):311-22. PMID: 23384597.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    281. A progressive dopaminergic phenotype associated with neurotoxic conversion of a-synuclein in BAC-transgenic rats. Brain. 2013 Feb; 136(Pt 2):412-32. PMID: 23413261.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    282. APOE e4 increases risk for dementia in pure synucleinopathies. JAMA Neurol. 2013 Feb; 70(2):223-8. PMID: 23407718.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    283. Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer. J Neurovirol. 2013 Feb; 19(1):89-101. PMID: 23341224.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    284. Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice. Neurobiol Aging. 2013 Jun; 34(6):1523-9. PMID: 23332171.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    285. Axonopathy in an a-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated a-synuclein. Am J Pathol. 2013 Mar; 182(3):940-53. PMID: 23313024.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    286. Time course and progression of wild type a-synuclein accumulation in a transgenic mouse model. BMC Neurosci. 2013 Jan 09; 14:6. PMID: 23302418.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    287. Alzheimer's disease: recent advances and future perspectives. J Alzheimers Dis. 2013; 33 Suppl 1:S185-94. PMID: 22810100.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    288. The many faces of a-synuclein: from structure and toxicity to therapeutic target. Nat Rev Neurosci. 2013 01; 14(1):38-48. PMID: 23254192.
      View in: PubMed   Mentions: 392     Fields:    Translation:HumansAnimalsCells
    289. Neuron-released oligomeric a-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia. Nat Commun. 2013; 4:1562. PMID: 23463005.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansAnimalsCells
    290. A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation. Mol Biol Cell. 2013 Feb; 24(3):194-209. PMID: 23223568.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    291. Cerebral ß-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE e4 carriers. AIDS. 2012 Nov 28; 26(18):2327-35. PMID: 23018443.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    292. Alzheimer brain-derived amyloid ß-protein impairs synaptic remodeling and memory consolidation. Neurobiol Aging. 2013 May; 34(5):1315-27. PMID: 23182244.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    293. Role of a-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. J Neurosci. 2012 Nov 21; 32(47):16906-16. PMID: 23175842.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    294. Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease. J Neurosci Res. 2013 Feb; 91(2):167-77. PMID: 23152192.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    295. Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. J Neurosci. 2012 Oct 31; 32(44):15565-76. PMID: 23115192.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    296. GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology. 2012 Nov 06; 79(19):1944-50. PMID: 23035075.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    297. Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease. Mol Neurodegener. 2012 Sep 28; 7:49. PMID: 23017109.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    298. Antibody-aided clearance of extracellular a-synuclein prevents cell-to-cell aggregate transmission. J Neurosci. 2012 Sep 26; 32(39):13454-69. PMID: 23015436.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    299. The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PLoS One. 2012; 7(9):e46178. PMID: 23049970.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    300. Distinct mechanisms of axonal globule formation in mice expressing human wild type a-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein. Mol Brain. 2012 Sep 26; 5:34. PMID: 23013868.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    301. Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits. PLoS One. 2012; 7(9):e45881. PMID: 23029293.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    302. Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. J Neuroinflammation. 2012 Sep 18; 9:220. PMID: 22989354.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    303. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 2012 Sep 13; 489(7415):304-8. PMID: 22972301.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansCells
    304. Early visuospatial deficits predict the occurrence of visual hallucinations in autopsy-confirmed dementia with Lewy bodies. Am J Geriatr Psychiatry. 2012 Sep; 20(9):773-81. PMID: 21997600.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    305. Alzheimer's ß-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of ß-amyloid. J Neurosci. 2012 Aug 15; 32(33):11390-5. PMID: 22895721.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    306. Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration. J Neurosci. 2012 Aug 08; 32(32):10971-81. PMID: 22875931.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    307. Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13733-8. PMID: 22869751.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    308. F-spondin gene transfer improves memory performance and reduces amyloid-ß levels in mice. Neuroscience. 2012 Oct 25; 223:465-72. PMID: 22863679.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    309. a-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. J Biol Chem. 2012 Sep 14; 287(38):31691-702. PMID: 22833673.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    310. In vivo alterations in calcium buffering capacity in transgenic mouse model of synucleinopathy. J Neurosci. 2012 Jul 18; 32(29):9992-8. PMID: 22815513.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    311. PGC-1a rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function. Sci Transl Med. 2012 Jul 11; 4(142):142ra97. PMID: 22786682.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    312. Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein. Exp Neurol. 2012 Oct; 237(2):318-34. PMID: 22750327.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    313. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. PMID: 22722634.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    314. Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Mov Disord. 2012 Aug; 27(9):1099-103. PMID: 22674458.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    315. Preventive immunization of aged and juvenile non-human primates to ß-amyloid. J Neuroinflammation. 2012 May 03; 9:84. PMID: 22554253.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsPHPublic Health
    316. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. PMID: 22556362.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    317. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol. 2012 May; 71(5):362-81. PMID: 22487856.
      View in: PubMed   Mentions: 461     Fields:    Translation:HumansCells
    318. Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway. Autophagy. 2012 May 01; 8(5):754-66. PMID: 22647715.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    319. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell. 2012 Apr 27; 149(3):708-21. PMID: 22541439.
      View in: PubMed   Mentions: 285     Fields:    Translation:HumansAnimalsCells
    320. Lentivirus mediated delivery of neurosin promotes clearance of wild-type a-synuclein and reduces the pathology in an a-synuclein model of LBD. Mol Ther. 2013 Jan; 21(1):31-41. PMID: 22508489.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    321. Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy. PLoS One. 2012; 7(4):e34713. PMID: 22514658.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    322. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease. Hum Mol Genet. 2012 Jul 15; 21(14):3097-111. PMID: 22492998.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    323. The pharmacology of neurotrophic treatment with Cerebrolysin: brain protection and repair to counteract pathologies of acute and chronic neurological disorders. Drugs Today (Barc). 2012 Apr; 48 Suppl A:3-24. PMID: 22514792.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    324. Prion infection promotes extensive accumulation of a-synuclein in aged human a-synuclein transgenic mice. Prion. 2012 Apr-Jun; 6(2):184-90. PMID: 22460692.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    325. Antioxidant sestrin-2 redistribution to neuronal soma in human immunodeficiency virus-associated neurocognitive disorders. J Neuroimmune Pharmacol. 2012 Sep; 7(3):579-90. PMID: 22450766.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    326. Neuronal to oligodendroglial a-synuclein redistribution in a double transgenic model of multiple system atrophy. Neuroreport. 2012 Mar 07; 23(4):259-64. PMID: 22314685.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    327. Protein analysis through Western blot of cells excised individually from human brain and muscle tissue. Anal Biochem. 2012 Jun 15; 425(2):120-4. PMID: 22402104.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    328. Role of a-synuclein penetration into the membrane in the mechanisms of oligomer pore formation. FEBS J. 2012 Mar; 279(6):1000-13. PMID: 22251432.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    329. Cognitive deficits in a mouse model of pre-manifest Parkinson's disease. Eur J Neurosci. 2012 Mar; 35(6):870-82. PMID: 22356593.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    330. Suppression of a-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context. Hum Mol Genet. 2012 Jun 01; 21(11):2432-49. PMID: 22357655.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    331. a-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. J Biol Chem. 2012 May 04; 287(19):15345-64. PMID: 22315227.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    332. Biochemical properties of highly neuroinvasive prion strains. PLoS Pathog. 2012 Feb; 8(2):e1002522. PMID: 22319450.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    333. Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of a-synucleinopathy. Exp Neurol. 2012 Apr; 234(2):405-16. PMID: 22281106.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    334. Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders. J Neurovirol. 2012 Aug; 18(4):313-22. PMID: 22234543.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    335. Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease. J Neurosci. 2012 Jan 04; 32(1):133-42. PMID: 22219276.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    336. Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model. Eur J Neurosci. 2012 Jan; 35(1):10-9. PMID: 22211740.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    337. Autophagy in dementias. Brain Pathol. 2012 Jan; 22(1):99-109. PMID: 22150925.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    338. Cell-to-cell transmission of a-synuclein aggregates. Methods Mol Biol. 2012; 849:347-59. PMID: 22528101.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    339. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement. 2012 Jan; 8(1):1-13. PMID: 22265587.
      View in: PubMed   Mentions: 569     Fields:    Translation:Humans
    340. Detection of peri-synaptic amyloid-ß pyroglutamate aggregates in early stages of Alzheimer's disease and in AßPP transgenic mice using a novel monoclonal antibody. J Alzheimers Dis. 2012; 28(4):783-94. PMID: 22064070.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    341. Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions. Mol Brain. 2011 Dec 21; 4:43. PMID: 22188897.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    342. Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease. PLoS One. 2011; 6(12):e29257. PMID: 22206005.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    343. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Mol Neurodegener. 2011 Dec 13; 6:83. PMID: 22165993.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    344. Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease. Neuroscience. 2012 Jan 27; 202:405-12. PMID: 22178988.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    345. Alzheimer disease: AD pathology--emerging subtypes or age-of-onset spectrum? Nat Rev Neurol. 2011 Dec 06; 8(1):11-2. PMID: 22143361.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    346. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol. 2012 Jan; 123(1):1-11. PMID: 22101365.
      View in: PubMed   Mentions: 601     Fields:    Translation:Humans
    347. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol. 2011 Oct 30; 7(12):925-34. PMID: 22037470.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    348. Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of a-synuclein. J Neurosci. 2011 Oct 12; 31(41):14508-20. PMID: 21994367.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    349. Multiple system atrophy: a clinical and neuropathological perspective. Trends Neurosci. 2011 Nov; 34(11):581-90. PMID: 21962754.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    350. Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener. 2011 Sep 24; 6:67. PMID: 21943307.
      View in: PubMed   Mentions: 16     Fields:    
    351. Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia. J Neurosci Res. 2012 Jan; 90(1):288-306. Vázquez-Roque RA, Ramos B, Tecuatl C, Juárez I, Adame A, de la Cruz F, Zamudio S, Mena R, Rockenstein E, Masliah E, Flores G. PMID: 21932359.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    352. Neuropathological alterations in Alzheimer disease. Cold Spring Harb Perspect Med. 2011 Sep; 1(1):a006189. PMID: 22229116.
      View in: PubMed   Mentions: 587     Fields:    Translation:HumansCells
    353. Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective? J Neurosci. 2011 Aug 31; 31(35):12483-90. PMID: 21880910.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    354. MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model. PLoS One. 2011; 6(8):e24027. PMID: 21901155.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    355. Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease. BMC Neurosci. 2011 Aug 03; 12:79. PMID: 21812967.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    356. Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease. J Neurosci Res. 2011 Nov; 89(11):1812-21. PMID: 21793038.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    357. Bridging molecular genetics and biomarkers in lewy body and related disorders. Int J Alzheimers Dis. 2011; 2011:842475. Ho GJ, Liang W, Waragai M, Sekiyama K, Masliah E, Hashimoto M. PMID: 21760990.
      View in: PubMed   Mentions:
    358. Toll-like receptor 4 promotes a-synuclein clearance and survival of nigral dopaminergic neurons. Am J Pathol. 2011 Aug; 179(2):954-63. Stefanova N, Fellner L, Reindl M, Masliah E, Poewe W, Wenning GK. PMID: 21801874.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    359. Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling. J Neurovirol. 2011 Aug; 17(4):327-40. PMID: 21660601.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    360. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell. 2011 Jun 10; 145(6):863-74. PMID: 21640374.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansAnimals
    361. Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis. J Infect Dis. 2011 Jun 01; 203(11):1647-57. Zhou D, Masliah E, Spector SA. PMID: 21592995.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    362. Protein aggregate spreading in neurodegenerative diseases: problems and perspectives. Neurosci Res. 2011 Aug; 70(4):339-48. Lee SJ, Lim HS, Masliah E, Lee HJ. PMID: 21624403.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    363. Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation. Mol Neurodegener. 2011 May 19; 6:34. PMID: 21595948.
      View in: PubMed   Mentions: 49     Fields:    
    364. Enhanced phosphatase activity attenuates a-synucleinopathy in a mouse model. J Neurosci. 2011 May 11; 31(19):6963-71. PMID: 21562258.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    365. Expression of mannose binding lectin in HIV-1-infected brain: implications for HIV-related neuronal damage and neuroAIDS. Neurobehav HIV Med. 2011 May 01; 3:41-52. PMID: 21852898.
      View in: PubMed   Mentions:
    366. Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease. PLoS One. 2011 Apr 29; 6(4):e19338. Masliah E, Rockenstein E, Mante M, Crews L, Spencer B, Adame A, Patrick C, Trejo M, Ubhi K, Rohn TT, Mueller-Steiner S, Seubert P, Barbour R, McConlogue L, Buttini M, Games D, Schenk D. PMID: 21559417.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    367. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011 Jun 10; 286(23):20710-26. Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. PMID: 21489994.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    368. Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human a-synuclein. J Neurosci Res. 2011 Jul; 89(7):1091-102. Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. PMID: 21488084.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    369. CD8+ lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain. J Med Primatol. 2011 Oct; 40(5):300-9. Ratai EM, Pilkenton S, He J, Fell R, Bombardier JP, Joo CG, Lentz MR, Kim WK, Burdo TH, Autissier P, Annamalai L, Curran E, O'Neil SP, Westmoreland SV, Williams KC, Masliah E, Gilberto González R. PMID: 21463330.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    370. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. PMID: 21460841.
      View in: PubMed   Mentions: 748     Fields:    Translation:Humans
    371. Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine. Am J Pathol. 2011 Apr; 178(4):1646-61. PMID: 21435449.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    372. Hyperphosphorylated Tau in an a-synuclein-overexpressing transgenic model of Parkinson's disease. Eur J Neurosci. 2011 May; 33(9):1598-610. PMID: 21453448.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    373. Brain creatine elevation and N-Acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of neuroAIDS. Magn Reson Med. 2011 Sep; 66(3):625-34. Ratai EM, Annamalai L, Burdo T, Joo CG, Bombardier JP, Fell R, Hakimelahi R, He J, Lentz MR, Campbell J, Curran E, Halpern EF, Masliah E, Westmoreland SV, Williams KC, González RG. PMID: 21381104.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    374. Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med. 2011 Mar; 17(3):377-82. Song W, Chen J, Petrilli A, Liot G, Klinglmayr E, Zhou Y, Poquiz P, Tjong J, Pouladi MA, Hayden MR, Masliah E, Ellisman M, Rouiller I, Schwarzenbacher R, Bossy B, Perkins G, Bossy-Wetzel E. PMID: 21336284.
      View in: PubMed   Mentions: 189     Fields:    Translation:HumansAnimalsCells
    375. In vivo demonstration that alpha-synuclein oligomers are toxic. Proc Natl Acad Sci U S A. 2011 Mar 08; 108(10):4194-9. Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R. PMID: 21325059.
      View in: PubMed   Mentions: 403     Fields:    Translation:AnimalsCells
    376. ApoE4-Driven Accumulation of Intraneuronal Oligomerized Aß42 following Activation of the Amyloid Cascade In Vivo Is Mediated by a Gain of Function. Int J Alzheimers Dis. 2011 Feb 15; 2011:792070. Zepa L, Frenkel M, Belinson H, Kariv-Inbal Z, Kayed R, Masliah E, Michaelson DM. PMID: 21350674.
      View in: PubMed   Mentions:
    377. Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease. Cell Death Dis. 2011 Feb 10; 2:e120. PMID: 21368891.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    378. Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases. J Biol Chem. 2011 Mar 18; 286(11):9031-7. Desplats P, Spencer B, Coffee E, Patel P, Michael S, Patrick C, Adame A, Rockenstein E, Masliah E. PMID: 21296890.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    379. Peripheral delivery of a CNS targeted, metalo-protease reduces aß toxicity in a mouse model of Alzheimer's disease. PLoS One. 2011 Jan 31; 6(1):e16575. Spencer B, Marr RA, Gindi R, Potkar R, Michael S, Adame A, Rockenstein E, Verma IM, Masliah E. PMID: 21304989.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    380. Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AßPP transgenic mice. J Alzheimers Dis. 2011; 27(4):743-52. PMID: 21860085.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    381. A longitudinal study of behavioral deficits in an AßPP transgenic mouse model of Alzheimer's disease. J Alzheimers Dis. 2011; 25(2):231-43. Havas D, Hutter-Paier B, Ubhi K, Rockenstein E, Crailsheim K, Masliah E, Windisch M. PMID: 21403389.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    382. Neprilysin-2 is an important ß-amyloid degrading enzyme. Am J Pathol. 2011 Jan; 178(1):306-12. Hafez D, Huang JY, Huynh AM, Valtierra S, Rockenstein E, Bruno AM, Lu B, DesGroseillers L, Masliah E, Marr RA. PMID: 21224067.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    383. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol Dis. 2011 Jul; 43(1):68-78. PMID: 21081164.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    384. Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity. PLoS One. 2010 Nov 16; 5(11):e14020. Price DL, Rockenstein E, Ubhi K, Phung V, MacLean-Lewis N, Askay D, Cartier A, Spencer B, Patrick C, Desplats P, Ellisman MH, Masliah E. PMID: 21103359.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    385. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. Mol Neurodegener. 2010 Nov 10; 5:49. Kwak YD, Ma T, Diao S, Zhang X, Chen Y, Hsu J, Lipton SA, Masliah E, Xu H, Liao FF. PMID: 21067594.
      View in: PubMed   Mentions: 50     Fields:    
    386. Transsynaptic progression of amyloid-ß-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron. 2010 Nov 04; 68(3):428-41. Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, Kim D, Hamto P, Lo I, Yu GQ, Palop JJ, Masliah E, Mucke L. PMID: 21040845.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    387. A ß-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain. Nat Commun. 2010 Nov 02; 1:110. Fujita M, Sugama S, Sekiyama K, Sekigawa A, Tsukui T, Nakai M, Waragai M, Takenouchi T, Takamatsu Y, Wei J, Rockenstein E, Laspada AR, Masliah E, Inoue S, Hashimoto M. PMID: 21045828.
      View in: PubMed   Mentions: 36     Fields:    
    388. Recent advances in the development of immunotherapies for tauopathies. Exp Neurol. 2011 Aug; 230(2):157-61. Ubhi K, Masliah E. PMID: 20970422.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    389. Cell-to-cell transmission of non-prion protein aggregates. Nat Rev Neurol. 2010 12; 6(12):702-6. Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E. PMID: 21045796.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    390. The biochemical aftermath of anti-amyloid immunotherapy. Mol Neurodegener. 2010 Oct 07; 5:39. Maarouf CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Masliah E, Nicoll JA, Sabbagh MN, Beach TG, Castaño EM, Roher AE. PMID: 20929585.
      View in: PubMed   Mentions: 14     Fields:    
    391. Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals. J Neurovirol. 2010 Oct; 16(5):399-404. Tatro ET, Nguyen TB, Bousman CA, Masliah E, Grant I, Atkinson JH, Everall IP. PMID: 20726698.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    392. Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus, and nucleus accumbens in old rats after chronic donepezil administration. Synapse. 2010 Oct; 64(10):786-93. Alcantara-Gonzalez F, Juarez I, Solis O, Martinez-Tellez I, Camacho-Abrego I, Masliah E, Mena R, Flores G. PMID: 20336627.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    393. Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron. 2010 Sep 23; 67(6):953-66. Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. PMID: 20869593.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimalsCells
    394. Neuropathology of dementia with Lewy bodies in advanced age: a comparison with Alzheimer disease. Neurosci Lett. 2010 Nov 26; 485(3):222-7. Ubhi K, Peng K, Lessig S, Estrella J, Adame A, Galasko D, Salmon DP, Hansen LA, Kawas CH, Masliah E. PMID: 20849919.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    395. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci. 2010 Sep 15; 30(37):12252-62. Crews L, Adame A, Patrick C, Delaney A, Pham E, Rockenstein E, Hansen L, Masliah E. PMID: 20844121.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    396. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proc Natl Acad Sci U S A. 2010 Sep 28; 107(39):16970-5. Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, Clark LN, Small SA. PMID: 20837543.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    397. Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders. Ann Neurol. 2010 Sep; 68(3):342-52. Kang YJ, Digicaylioglu M, Russo R, Kaul M, Achim CL, Fletcher L, Masliah E, Lipton SA. PMID: 20818790.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    398. Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. PLoS One. 2010 Aug 23; 5(8):e12333. Clark J, Clore EL, Zheng K, Adame A, Masliah E, Simon DK. PMID: 20808797.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    399. Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat Cell Biol. 2010 Sep; 12(9):863-75. Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L. PMID: 20711182.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCells
    400. Reduced hypocretin (orexin) levels in dementia with Lewy bodies. Neuroreport. 2010 Aug 04; 21(11):756-60. Lessig S, Ubhi K, Galasko D, Adame A, Pham E, Remidios K, Chang M, Hansen LA, Masliah E. PMID: 20531237.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    401. Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. J Neurosci. 2010 Aug 04; 30(31):10541-50. Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. PMID: 20685997.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    402. Multiple non-cell autonomous actions of alpha-synuclein in neurodegenerative diseases: Is there a direct link? . 2010 Jul 15; 9(14):2696-7. Lee SJ, Lee HJ, Masliah E. PMID: 20647760.
      View in: PubMed   Mentions:
    403. Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. Am J Pathol. 2010 Aug; 177(2):563-9. Buttini M, Masliah E, Yu GQ, Palop JJ, Chang S, Bernardo A, Lin C, Wyss-Coray T, Huang Y, Mucke L. PMID: 20595630.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    404. Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins. FEBS J. 2010 Jul; 277(14):3051-67. Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E. PMID: 20573181.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    405. A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. J Neurosci. 2010 Jun 16; 30(24):8083-95. Scott DA, Tabarean I, Tang Y, Cartier A, Masliah E, Roy S. PMID: 20554859.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    406. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One. 2010 Jun 15; 5(6):e11102. Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T. PMID: 20559548.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    407. Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway. J Neurosci Res. 2010 Jun; 88(8):1764-76. Wu N, Joshi PR, Cepeda C, Masliah E, Levine MS. PMID: 20029978.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    408. In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility. PLoS One. 2010 May 11; 5(5):e10589. Unni VK, Weissman TA, Rockenstein E, Masliah E, McLean PJ, Hyman BT. PMID: 20485674.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    409. Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS. PLoS One. 2010 May 07; 5(5):e10523. Ratai EM, Bombardier JP, Joo CG, Annamalai L, Burdo TH, Campbell J, Fell R, Hakimelahi R, He J, Autissier P, Lentz MR, Halpern EF, Masliah E, Williams KC, Westmoreland SV, González RG. PMID: 20479889.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    410. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci. 2010 May 05; 30(18):6236-46. Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Whitney K, Masliah E. PMID: 20445049.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    411. Genetic deletion of Nogo/Rtn4 ameliorates behavioral and neuropathological outcomes in amyloid precursor protein transgenic mice. Neuroscience. 2010 Aug 11; 169(1):488-94. Masliah E, Xie F, Dayan S, Rockenstein E, Mante M, Adame A, Patrick CM, Chan AF, Zheng B. PMID: 20433905.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    412. Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-infected brain: novel analysis of retrospective cases. PLoS One. 2010 Apr 26; 5(4):e10337. Tatro ET, Scott ER, Nguyen TB, Salaria S, Banerjee S, Moore DJ, Masliah E, Achim CL, Everall IP. PMID: 20436668.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    413. Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy. Neuroreport. 2010 Apr 21; 21(6):457-62. Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Masliah E. PMID: 20224454.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    414. Molecular mechanisms of neurodegeneration in Alzheimer's disease. Hum Mol Genet. 2010 Apr 15; 19(R1):R12-20. Crews L, Masliah E. PMID: 20413653.
      View in: PubMed   Mentions: 166     Fields:    Translation:Humans
    415. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain. 2010 May; 133(Pt 5):1312-27. Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. PMID: 20360050.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    416. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci. 2010 Mar 03; 30(9):3184-98. Paleologou KE, Oueslati A, Shakked G, Rospigliosi CC, Kim HY, Lamberto GR, Fernandez CO, Schmid A, Chegini F, Gai WP, Chiappe D, Moniatte M, Schneider BL, Aebischer P, Eliezer D, Zweckstetter M, Masliah E, Lashuel HA. PMID: 20203178.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    417. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy. PLoS One. 2010 Feb 19; 5(2):e9313. Crews L, Spencer B, Desplats P, Patrick C, Paulino A, Rockenstein E, Hansen L, Adame A, Galasko D, Masliah E. PMID: 20174468.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    418. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet. 2010 Mar; 42(3):234-9. Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL, Ferrer I, Lladó A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, Lopez de Munain A, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, DeCarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tuñón MT, Martínez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM. PMID: 20154673.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansCells
    419. Can Alzheimer disease be prevented by amyloid-beta immunotherapy? Nat Rev Neurol. 2010 Feb; 6(2):108-19. Lemere CA, Masliah E. PMID: 20140000.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimals
    420. Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies. J Biol Chem. 2010 Mar 19; 285(12):9262-72. Lee HJ, Suk JE, Patrick C, Bae EJ, Cho JH, Rho S, Hwang D, Masliah E, Lee SJ. PMID: 20071342.
      View in: PubMed   Mentions: 271     Fields:    Translation:HumansAnimalsCells
    421. Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein. J Neurosci. 2010 Jan 06; 30(1):372-81. Harris JA, Devidze N, Halabisky B, Lo I, Thwin MT, Yu GQ, Bredesen DE, Masliah E, Mucke L. PMID: 20053918.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    422. Lentivirus-expressed siRNA vectors against Alzheimer disease. Methods Mol Biol. 2010; 614:215-24. Peng KA, Masliah E. PMID: 20225047.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    423. S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis. 2010; 20 Suppl 2:S513-26. Bossy B, Petrilli A, Klinglmayr E, Chen J, Lütz-Meindl U, Knott AB, Masliah E, Schwarzenbacher R, Bossy-Wetzel E. PMID: 20463395.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    424. Placenta accreta in a separate uterine horn. Pediatr Dev Pathol. 2010 Jan-Feb; 13(1):63-5. Baughn MR, Vaux K, Masliah E. PMID: 19642813.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    425. Following activation of the amyloid cascade, apolipoprotein E4 drives the in vivo oligomerization of amyloid-ß resulting in neurodegeneration. J Alzheimers Dis. 2010; 22(3):959-70. Belinson H, Kariv-Inbal Z, Kayed R, Masliah E, Michaelson DM. PMID: 20858958.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    426. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice. Cell. 2009 Dec 11; 139(6):1157-69. Cohen E, Paulsson JF, Blinder P, Burstyn-Cohen T, Du D, Estepa G, Adame A, Pham HM, Holzenberger M, Kelly JW, Masliah E, Dillin A. PMID: 20005808.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansAnimalsCells
    427. APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis. Brain Struct Funct. 2010 Mar; 214(2-3):111-26. Crews L, Rockenstein E, Masliah E. PMID: 20091183.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    428. Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies. Exp Neurol. 2010 Feb; 221(2):267-74. Koob AO, Ubhi K, Paulsson JF, Kelly J, Rockenstein E, Mante M, Adame A, Masliah E. PMID: 19944097.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    429. GFAP reactivity, apolipoprotein E redistribution and cholesterol reduction in human astrocytes treated with alpha-synuclein. Neurosci Lett. 2010 Jan 18; 469(1):11-4. Koob AO, Paulino AD, Masliah E. PMID: 19932737.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    430. Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice. Exp Neurol. 2010 Jun; 223(2):422-31. Jolivalt CG, Hurford R, Lee CA, Dumaop W, Rockenstein E, Masliah E. PMID: 19931251.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    431. Phosphorylation of synucleins by members of the Polo-like kinase family. J Biol Chem. 2010 Jan 22; 285(4):2807-22. Mbefo MK, Paleologou KE, Boucharaba A, Oueslati A, Schell H, Fournier M, Olschewski D, Yin G, Zweckstetter M, Masliah E, Kahle PJ, Hirling H, Lashuel HA. PMID: 19889641.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    432. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci. 2009 Oct 28; 29(43):13578-88. Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, Adame A, Wyss-Coray T, Masliah E. PMID: 19864570.
      View in: PubMed   Mentions: 236     Fields:    Translation:HumansAnimalsCells
    433. Glycogen synthase kinase-3beta (GSK-3beta) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons. J Neurovirol. 2009 Sep; 15(5-6):434-8. Nguyen TB, Lucero GR, Chana G, Hult BJ, Tatro ET, Masliah E, Grant I, Achim CL, Everall IP. PMID: 19688630.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    434. Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy. J Neurovirol. 2009 Sep; 15(5-6):360-70. Everall I, Vaida F, Khanlou N, Lazzaretto D, Achim C, Letendre S, Moore D, Ellis R, Cherner M, Gelman B, Morgello S, Singer E, Grant I, Masliah E. PMID: 20175693.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    435. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res. 2009 Sep; 87(12):2728-39. Ubhi K, Lee PH, Adame A, Inglis C, Mante M, Rockenstein E, Stefanova N, Wenning GK, Masliah E. PMID: 19405128.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    436. Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life. Neurobiol Dis. 2009 Nov; 36(2):293-302. Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. PMID: 19660551.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    437. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):13010-5. Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee SJ. PMID: 19651612.
      View in: PubMed   Mentions: 561     Fields:    Translation:HumansAnimalsCells
    438. Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. Exp Neurol. 2009 Oct; 219(2):543-52. Winner B, Desplats P, Hagl C, Klucken J, Aigner R, Ploetz S, Laemke J, Karl A, Aigner L, Masliah E, Buerger E, Winkler J. PMID: 19619535.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    439. Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. J Neurosci. 2009 Jul 15; 29(28):9104-14. Wacker JL, Huang SY, Steele AD, Aron R, Lotz GP, Nguyen Q, Giorgini F, Roberson ED, Lindquist S, Masliah E, Muchowski PJ. PMID: 19605647.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    440. Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease. J Neurosci. 2009 Jul 08; 29(27):8805-15. Dziewczapolski G, Glogowski CM, Masliah E, Heinemann SF. PMID: 19587288.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    441. Role of synucleins in Alzheimer's disease. Neurotox Res. 2009 Oct; 16(3):306-17. Crews L, Tsigelny I, Hashimoto M, Masliah E. PMID: 19551456.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    442. Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. J Neurosci. 2009 Jun 17; 29(24):7857-68. Cartier AE, Djakovic SN, Salehi A, Wilson SM, Masliah E, Patrick GN. PMID: 19535597.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    443. Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks. J Comp Neurol. 2009 May 20; 514(3):240-58. Belichenko PV, Wright EE, Belichenko NP, Masliah E, Li HH, Mobley WC, Francke U. PMID: 19296534.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    444. p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7870-5. Bengoechea TG, Chen Z, O'Leary DA, O'Leary D, Masliah E, Lee KF. PMID: 19416837.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    445. Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies. Am J Pathol. 2009 May; 174(5):1891-909. Wei J, Fujita M, Nakai M, Waragai M, Sekigawa A, Sugama S, Takenouchi T, Masliah E, Hashimoto M. PMID: 19349362.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    446. Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease. FEBS J. 2009 May; 276(10):2736-51. Shaked GM, Chauv S, Ubhi K, Hansen LA, Masliah E. PMID: 19368557.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    447. Increased frequency of alpha-synuclein in the substantia nigra in human immunodeficiency virus infection. J Neurovirol. 2009 Apr; 15(2):131-8. Khanlou N, Moore DJ, Chana G, Cherner M, Lazzaretto D, Dawes S, Grant I, Masliah E, Everall IP. PMID: 19115126.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    448. Extensive HIV-1 intra-host recombination is common in tissues with abnormal histopathology. PLoS One. 2009; 4(3):e5065. Lamers SL, Salemi M, Galligan DC, de Oliveira T, Fogel GB, Granier SC, Zhao L, Brown JN, Morris A, Masliah E, McGrath MS. PMID: 19333384.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    449. Association of early experience with neurodegeneration in aged primates. Neurobiol Aging. 2011 Jan; 32(1):151-6. Merrill DA, Masliah E, Roberts JA, McKay H, Kordower JH, Mufson EJ, Tuszynski MH. PMID: 19321231.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    450. Increased accumulation of intraneuronal amyloid beta in HIV-infected patients. J Neuroimmune Pharmacol. 2009 Jun; 4(2):190-9. Achim CL, Adame A, Dumaop W, Everall IP, Masliah E. PMID: 19288297.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    451. Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein. Neuroscience. 2009 Mar 17; 159(2):501-13. Watson JB, Hatami A, David H, Masliah E, Roberts K, Evans CE, Levine MS. PMID: 19361478.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    452. Molecular pathology of neuro-AIDS (CNS-HIV). Int J Mol Sci. 2009 Mar; 10(3):1045-63. Crews L, Patrick C, Achim CL, Everall IP, Masliah E. PMID: 19399237.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    453. Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin. Acta Neuropathol. 2009 Jun; 117(6):699-712. Ubhi K, Rockenstein E, Doppler E, Mante M, Adame A, Patrick C, Trejo M, Crews L, Paulino A, Moessler H, Masliah E. PMID: 19252918.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    454. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med. 2009 Mar; 15(3):331-7. Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, Chiba AA, Tuszynski MH. PMID: 19198615.
      View in: PubMed   Mentions: 301     Fields:    Translation:Animals
    455. Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder. J Neuroimmune Pharmacol. 2009 Jun; 4(2):218-26. Tatro ET, Everall IP, Masliah E, Hult BJ, Lucero G, Chana G, Soontornniyomkij V, Achim CL. PMID: 19199039.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    456. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2097-103. Chu J, Hong NA, Masuda CA, Jenkins BV, Nelms KA, Goodnow CC, Glynne RJ, Wu H, Masliah E, Joazeiro CA, Kay SA. PMID: 19196968.
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