Nigel Calcutt

Title(s)Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Selection of a lead LPAR1 antagonist for treatment of diabetic neuropathy
    NIH R44DK127879May 20, 2021 - Apr 30, 2023
    Role: Co-Principal Investigator
    Development of a topical fixed-dose combination drug for peripheral neuropathic pain.
    NIH R41NS120354Sep 30, 2020 - Aug 31, 2022
    Role: Co-Principal Investigator
    Muscarinic receptor antagonists as a therapy for diabetic neuropathy
    NIH R21DK102032Aug 1, 2014 - Jul 31, 2017
    Role: Principal Investigator
    Cholinergic constraint and diabetic neuropathy
    NIH R01NS081082Jul 1, 2013 - Jun 30, 2019
    Role: Principal Investigator
    Non Phamacologic Treatments for Diabetic Neuropathy
    NIH R21NS062346Feb 1, 2009 - Jan 31, 2012
    Role: Principal Investigator
    Near Infra Red Energy To Treat Diabetic Neuropathy
    NIH R21NS050232Jul 1, 2005 - Jun 30, 2007
    Role: Principal Investigator
    Mechanisms of Spinally-Mediated Hyperalgesia in Diabetes
    NIH R01DK057629Apr 1, 2000 - Jul 31, 2014
    Role: Principal Investigator
    PROSAPOSIN AND PROSAPTIDES IN DIABETIC NEUROPATHY
    NIH R01NS038855Sep 30, 1999 - Aug 31, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rate-Dependent Depression: A Predictor of the Therapeutic Efficacy in Treating Painful Diabetic Peripheral Neuropathy. Diabetes. 2022 06 01; 71(6):1272-1281. Zhou X, Zhu Y, Wang Z, Lin Z, Zhu D, Xie C, Calcutt NA, Guan Y. PMID: 35234842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Using Corneal Confocal Microscopy to Identify Therapeutic Agents for Diabetic Neuropathy. J Clin Med. 2022 Apr 21; 11(9). Jolivalt CG, Han MM, Nguyen A, Desmond F, Alves Jesus CH, Vasconselos DC, Pedneault A, Sandlin N, Dunne-Cerami S, Frizzi KE, Calcutt NA. PMID: 35566433; PMCID: PMC9104226.
      View in: PubMed   Mentions:
    3. CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth. Cell Mol Life Sci. 2022 Mar 17; 79(4):193. Aghanoori MR, Agarwal P, Gauvin E, Nagalingam RS, Bonomo R, Yathindranath V, Smith DR, Hai Y, Lee S, Jolivalt CG, Calcutt NA, Jones MJ, Czubryt MP, Miller DW, Dolinsky VW, Mansuy-Aubert V, Fernyhough P. PMID: 35298717; PMCID: PMC8930798.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice. J Neuroinflammation. 2022 Feb 26; 19(1):57. Gavini CK, Elshareif N, Aubert G, Germanwala AV, Calcutt NA, Mansuy-Aubert V. PMID: 35219337; PMCID: PMC8882298.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    5. Rate-dependent depression is impaired in amyotrophic lateral sclerosis. Neurol Sci. 2022 Mar; 43(3):1831-1838. Zhou X, Wang Z, Lin Z, Zhu Y, Zhu D, Xie C, Calcutt NA, Guan Y. PMID: 34518934.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Optimal Utility of H-Reflex RDD as a Biomarker of Spinal Disinhibition in Painful and Painless Diabetic Neuropathy. Diagnostics (Basel). 2021 Jul 12; 11(7). Worthington A, Kalteniece A, Ferdousi M, D'Onofrio L, Dhage S, Azmi S, Adamson C, Hamdy S, Malik RA, Calcutt NA, Marshall AG. PMID: 34359330; PMCID: PMC8306975.
      View in: PubMed   Mentions:
    7. Spinal Inhibitory Dysfunction in Patients With Painful or Painless Diabetic Neuropathy. Diabetes Care. 2021 08; 44(8):1835-1841. Worthington A, Kalteniece A, Ferdousi M, D'Onofrio L, Dhage S, Azmi S, Adamson C, Hamdy S, Malik RA, Calcutt NA, Marshall AG. PMID: 34385346.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Prevention of HIV-1 TAT Protein-Induced Peripheral Neuropathy and Mitochondrial Disruption by the Antimuscarinic Pirenzepine. Front Neurol. 2021; 12:663373. Han MM, Frizzi KE, Ellis RJ, Calcutt NA, Fields JA. PMID: 34211430; PMCID: PMC8239242.
      View in: PubMed   Mentions: 2  
    9. Lost in Translation? Measuring Diabetic Neuropathy in Humans and Animals (Diabetes Metab J 2021;45:27-42). Diabetes Metab J. 2021 05; 45(3):457-458. Jin HY, Moon SS, Calcutt NA. PMID: 34044488; PMCID: PMC8164954.
      View in: PubMed   Mentions: Translation:HumansAnimals
    10. Novel and Emerging Electrophysiological Biomarkers of Diabetic Neuropathy and Painful Diabetic Neuropathy. Clin Ther. 2021 09; 43(9):1441-1456. Marshall A, Alam U, Themistocleous A, Calcutt N, Marshall A. PMID: 33906790.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic Efficacy against Painful Diabetic Neuropathy. Diagnostics (Basel). 2021 Feb 11; 11(2). Lee-Kubli CA, Zhou X, Jolivalt CG, Calcutt NA. PMID: 33670344; PMCID: PMC7917809.
      View in: PubMed   Mentions: 4  
    12. Lost in Translation? Measuring Diabetic Neuropathy in Humans and Animals. Diabetes Metab J. 2021 01; 45(1):27-42. Jin HY, Moon SS, Calcutt NA. PMID: 33307618; PMCID: PMC7850880.
      View in: PubMed   Mentions: 6  Translation:HumansAnimalsCells
    13. Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system. Expert Rev Neurother. 2021 01; 21(1):45-63. Demaré S, Kothari A, Calcutt NA, Fernyhough P. PMID: 33161784; PMCID: PMC9482886.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    14. Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice. Proc Natl Acad Sci U S A. 2020 10 20; 117(42):26482-26493. Bonomo RR, Cook TM, Gavini CK, White CR, Jones JR, Bovo E, Zima AV, Brown IA, Dugas LR, Zakharian E, Aubert G, Alonzo F, Calcutt NA, Mansuy-Aubert V. PMID: 33020290; PMCID: PMC7584890.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    15. Diabetic neuropathy and neuropathic pain: a (con)fusion of pathogenic mechanisms? Pain. 2020 09; 161(Suppl 1):S65-S86. Calcutt NA. PMID: 32999525; PMCID: PMC7521457.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    16. A missense point mutation in nerve growth factor (NGFR100W) results in selective peripheral sensory neuropathy. Prog Neurobiol. 2020 11; 194:101886. Yang W, Sung K, Xu W, Rodriguez MJ, Wu AC, Santos SA, Fang S, Uber RK, Dong SX, Guillory BC, Orain X, Raus J, Jolivalt C, Calcutt N, Rissman RA, Ding J, Wu C. PMID: 32693191.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    17. Predictors of worsening neuropathy and neuropathic pain after 12 years in people with HIV. Ann Clin Transl Neurol. 2020 07; 7(7):1166-1173. Ellis RJ, Diaz M, Sacktor N, Marra C, Collier AC, Clifford DB, Calcutt N, Fields JA, Heaton RK, Letendre SL, CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group. PMID: 32619341; PMCID: PMC7359117.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Translating diabetic peripheral neuropathy. J Peripher Nerv Syst. 2020 06; 25(2):64-65. Malik RA, Calcutt NA. PMID: 32394617.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Topical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic Mice. J Pharmacol Exp Ther. 2020 07; 374(1):44-51. Jolivalt CG, Frizzi KE, Han MM, Mota AJ, Guernsey LS, Kotra LP, Fernyhough P, Calcutt NA. PMID: 32327528; PMCID: PMC7292964.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    20. Muscarinic Toxin 7 Signals Via Ca2+/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration. Mol Neurobiol. 2020 Jun; 57(6):2521-2538. Saleh A, Sabbir MG, Aghanoori MR, Smith DR, Roy Chowdhury SK, Tessler L, Brown J, Gedarevich E, Kassahun MZ, Frizzi K, Calcutt NA, Fernyhough P. PMID: 32198698; PMCID: PMC7253379.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    21. Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. Sci Rep. 2019 11 20; 9(1):17158. Fields JA, Swinton MK, Carson A, Soontornniyomkij B, Lindsay C, Han MM, Frizzi K, Sambhwani S, Murphy A, Achim CL, Ellis RJ, Calcutt NA. PMID: 31748578; PMCID: PMC6868155.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    22. Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189. Diabetes. 2019 11; 68(11):2143-2154. Jolivalt CG, Marquez A, Quach D, Navarro Diaz MC, Anaya C, Kifle B, Muttalib N, Sanchez G, Guernsey L, Hefferan M, Smith DR, Fernyhough P, Johe K, Calcutt NA. PMID: 31492662; PMCID: PMC6804627.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Dichloroacetate-induced peripheral neuropathy. Int Rev Neurobiol. 2019; 145:211-238. Stacpoole PW, Martyniuk CJ, James MO, Calcutt NA. PMID: 31208525.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    24. Preface. Int Rev Neurobiol. 2019; 145:xi-xii. Fernyhough P, Calcutt NA. PMID: 31208529.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Diabetic Neuropathy: New Insights to Early Diagnosis and Treatments. J Diabetes Res. 2018; 2018:5378439. Yorek M, Malik RA, Calcutt NA, Vinik A, Yagihashi S. PMID: 30648115; PMCID: PMC6311826.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsPHPublic Health
    26. Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes. Mol Metab. 2019 02; 20:149-165. Aghanoori MR, Smith DR, Shariati-Ievari S, Ajisebutu A, Nguyen A, Desmond F, Jesus CHA, Zhou X, Calcutt NA, Aliani M, Fernyhough P. PMID: 30545741; PMCID: PMC6358538.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons. Front Neurosci. 2018; 12:402. Sabbir MG, Calcutt NA, Fernyhough P. PMID: 29997469; PMCID: PMC6029366.
      View in: PubMed   Mentions: 9  
    28. Internode length is reduced during myelination and remyelination by neurofilament medium phosphorylation in motor axons. Exp Neurol. 2018 08; 306:158-168. Villalón E, Barry DM, Byers N, Frizzi K, Jones MR, Landayan DS, Dale JM, Downer NL, Calcutt NA, Garcia ML. PMID: 29772247; PMCID: PMC5994378.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    29. The H-Reflex as a Biomarker for Spinal Disinhibition in Painful Diabetic Neuropathy. Curr Diab Rep. 2018 01 23; 18(1):1. Lee-Kubli C, Marshall AG, Malik RA, Calcutt NA. PMID: 29362940; PMCID: PMC6876556.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    30. A novel curcumin derivative for the treatment of diabetic neuropathy. Neuropharmacology. 2018 Feb; 129:26-35. Daugherty DJ, Marquez A, Calcutt NA, Schubert D. PMID: 29122628; PMCID: PMC5841546.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    31. Insulin prevents aberrant mitochondrial phenotype in sensory neurons of type 1 diabetic rats. Exp Neurol. 2017 11; 297:148-157. Aghanoori MR, Smith DR, Roy Chowdhury S, Sabbir MG, Calcutt NA, Fernyhough P. PMID: 28803751; PMCID: PMC5612919.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    32. Differential effects of myostatin deficiency on motor and sensory axons. Muscle Nerve. 2017 Dec; 56(6):E100-E107. Jones MR, Villalón E, Northcutt AJ, Calcutt NA, Garcia ML. PMID: 28073155; PMCID: PMC5503820.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    33. Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy. Diabetes. 2017 05; 66(5):1380-1390. Marshall AG, Lee-Kubli C, Azmi S, Zhang M, Ferdousi M, Mixcoatl-Zecuatl T, Petropoulos IN, Ponirakis G, Fineman MS, Fadavi H, Frizzi K, Tavakoli M, Jeziorska M, Jolivalt CG, Boulton AJM, Efron N, Calcutt NA, Malik RA. PMID: 28202580; PMCID: PMC5399611.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    34. Schwann cell interactions with axons and microvessels in diabetic neuropathy. Nat Rev Neurol. 2017 03; 13(3):135-147. Gonçalves NP, Vægter CB, Andersen H, Østergaard L, Calcutt NA, Jensen TS. PMID: 28134254; PMCID: PMC7391875.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    35. Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest. 2017 Feb 01; 127(2):608-622. Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P. PMID: 28094765; PMCID: PMC5272197.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    36. Peripheral Neuropathy in Mouse Models of Diabetes. Curr Protoc Mouse Biol. 2016 Sep 01; 6(3):223-255. Jolivalt CG, Frizzi KE, Guernsey L, Marquez A, Ochoa J, Rodriguez M, Calcutt NA. PMID: 27584552; PMCID: PMC5023323.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    37. A Brief Introduction to the History and Controversies of Clinical Trials in Diabetic Neuropathy. Int Rev Neurobiol. 2016; 127:3-8. Calcutt NA, Fernyhough P. PMID: 27133141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    38. An Introduction to the History and Controversies of Animal Models of Diabetic Neuropathy. Int Rev Neurobiol. 2016; 127:45-52. Calcutt NA, Fernyhough P. PMID: 27133144.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    39. An Introduction to the History and Controversies of the Pathogenesis of Diabetic Neuropathy. Int Rev Neurobiol. 2016; 127:115-20. Fernyhough P, Calcutt NA. PMID: 27133147.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. New Directions in Diabetic Neuropathy: Evolution or Extinction? Int Rev Neurobiol. 2016; 127:229-34. Fernyhough P, Calcutt NA. PMID: 27133152.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    41. The α5 subunit containing GABAA receptors contribute to chronic pain. Pain. 2016 Mar; 157(3):613-626. Bravo-Hernández M, Corleto JA, Barragán-Iglesias P, González-Ramírez R, Pineda-Farias JB, Felix R, Calcutt NA, Delgado-Lezama R, Marsala M, Granados-Soto V. PMID: 26545088; PMCID: PMC4950669.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    42. Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation. Invest Ophthalmol Vis Sci. 2015 Nov; 56(12):7214-23. Rocca CJ, Kreymerman A, Ur SN, Frizzi KE, Naphade S, Lau A, Tran T, Calcutt NA, Goldberg JL, Cherqui S. PMID: 26540660; PMCID: PMC4640476.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    43. Efficacy of a long-acting C-peptide analogue against peripheral neuropathy in streptozotocin-diabetic mice. Diabetes Obes Metab. 2015 Aug; 17(8):781-8. Jolivalt CG, Rodriguez M, Wahren J, Calcutt NA. PMID: 25904006.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    44. Remodelling of spared proprioceptive circuit involving a small number of neurons supports functional recovery. Nat Commun. 2015 Jan 19; 6:6079. Hollis ER, Ishiko N, Pessian M, Tolentino K, Lee-Kubli CA, Calcutt NA, Zou Y. PMID: 25597627; PMCID: PMC4831586.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    45. A novel and robust conditioning lesion induced by ethidium bromide. Exp Neurol. 2015 Mar; 265:30-9. Hollis ER, Ishiko N, Tolentino K, Doherty E, Rodriguez MJ, Calcutt NA, Zou Y. PMID: 25541322; PMCID: PMC4346483.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab). J Peripher Nerv Syst. 2014 Jun; 19(2):77-87. Biessels GJ, Bril V, Calcutt NA, Cameron NE, Cotter MA, Dobrowsky R, Feldman EL, Fernyhough P, Jakobsen J, Malik RA, Mizisin AP, Oates PJ, Obrosova IG, Pop-Busui R, Russell JW, Sima AA, Stevens MJ, Schmidt RE, Tesfaye S, Veves A, Vinik AI, Wright DE, Yagihashi S, Yorek MA, Ziegler D, Zochodne DW. PMID: 24934510; PMCID: PMC4303044.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    47. Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents. Cell Mol Neurobiol. 2014 Jul; 34(5):643-9. Chowdhury SR, Saleh A, Akude E, Smith DR, Morrow D, Tessler L, Calcutt NA, Fernyhough P. PMID: 24682898.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    48. Treating small fiber neuropathy by topical application of a small molecule modulator of ligand-induced GFRα/RET receptor signaling. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):2325-30. Hedstrom KL, Murtie JC, Albers K, Calcutt NA, Corfas G. PMID: 24449858; PMCID: PMC3926041.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    49. Painful neuropathy: Mechanisms. Handb Clin Neurol. 2014; 126:533-57. Lee-Kubli CA, Calcutt NA. PMID: 25410243.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    50. Animal models of diabetes-induced neuropathic pain. Curr Top Behav Neurosci. 2014; 20:147-70. Lee-Kubli CA, Mixcoatl-Zecuatl T, Jolivalt CG, Calcutt NA. PMID: 24510303.
      View in: PubMed   Mentions: 9     Fields:    
    51. Repeated monitoring of corneal nerves by confocal microscopy as an index of peripheral neuropathy in type-1 diabetic rodents and the effects of topical insulin. J Peripher Nerv Syst. 2013 Dec; 18(4):306-15. Chen DK, Frizzi KE, Guernsey LS, Ladt K, Mizisin AP, Calcutt NA. PMID: 24147903; PMCID: PMC3981941.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    52. Location, location, location?: is the pain of diabetic neuropathy generated by hyperactive sensory neurons? Diabetes. 2013 Nov; 62(11):3658-60. Calcutt NA. PMID: 24158992; PMCID: PMC3806595.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    53. Altered rate-dependent depression of the spinal H-reflex as an indicator of spinal disinhibition in models of neuropathic pain. Pain. 2014 Feb; 155(2):250-260. Lee-Kubli CAG, Calcutt NA. PMID: 24103402; PMCID: PMC3946970.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    54. Guaifenesin derivatives promote neurite outgrowth and protect diabetic mice from neuropathy. J Med Chem. 2013 Jun 27; 56(12):5071-8. Hadimani MB, Purohit MK, Vanampally C, Van der Ploeg R, Arballo V, Morrow D, Frizzi KE, Calcutt NA, Fernyhough P, Kotra LP. PMID: 23758573.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    55. Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents. Neuropharmacology. 2013 Feb; 65:65-73. Saleh A, Roy Chowdhury SK, Smith DR, Balakrishnan S, Tessler L, Martens C, Morrow D, Schartner E, Frizzi KE, Calcutt NA, Fernyhough P. PMID: 23022047; PMCID: PMC3521091.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    56. Hypertension-induced peripheral neuropathy and the combined effects of hypertension and diabetes on nerve structure and function in rats. Acta Neuropathol. 2012 Oct; 124(4):561-73. Gregory JA, Jolivalt CG, Goor J, Mizisin AP, Calcutt NA. PMID: 22791295.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    57. Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes. Brain. 2012 Jun; 135(Pt 6):1751-66. Roy Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P. PMID: 22561641; PMCID: PMC3359752.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    58. Expansion of neurofilament medium C terminus increases axonal diameter independent of increases in conduction velocity or myelin thickness. J Neurosci. 2012 May 02; 32(18):6209-19. Barry DM, Stevenson W, Bober BG, Wiese PJ, Dale JM, Barry GS, Byers NS, Strope JD, Chang R, Schulz DJ, Shah S, Calcutt NA, Gebremichael Y, Garcia ML. PMID: 22553027; PMCID: PMC3363292.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    59. Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease. Neuroscience. 2012 Jan 27; 202:405-12. Jolivalt CG, Calcutt NA, Masliah E. PMID: 22178988; PMCID: PMC3268846.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    60. GLP-1 signals via ERK in peripheral nerve and prevents nerve dysfunction in diabetic mice. Diabetes Obes Metab. 2011 Nov; 13(11):990-1000. Jolivalt CG, Fineman M, Deacon CF, Carr RD, Calcutt NA. PMID: 21635674; PMCID: PMC3177968.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    61. Considerations for quantification of lipids in nerve tissue using matrix-assisted laser desorption/ionization mass spectrometric imaging. Rapid Commun Mass Spectrom. 2011 Oct 30; 25(20):3178-84. Landgraf RR, Garrett TJ, Conaway MC, Calcutt NA, Stacpoole PW, Yost RA. PMID: 21953974; PMCID: PMC3926214.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    62. Muscle pathology without severe nerve pathology in a new mouse model of Charcot-Marie-Tooth disease type 2E. Hum Mol Genet. 2011 Jul 01; 20(13):2535-48. Shen H, Barry DM, Dale JM, Garcia VB, Calcutt NA, Garcia ML. PMID: 21493625; PMCID: PMC3109999.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    63. Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1. J Pharmacol Exp Ther. 2011 Jan; 336(1):87-94. Li W, James MO, McKenzie SC, Calcutt NA, Liu C, Stacpoole PW. PMID: 20884751; PMCID: PMC3014303.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    64. Tolerating diabetes: an alternative therapeutic approach for diabetic neuropathy. ASN Neuro. 2010 Sep 09; 2(4):e00042. Calcutt NA. PMID: 20842208; PMCID: PMC2936743.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    65. Diet-induced obesity in Sprague-Dawley rats causes microvascular and neural dysfunction. Diabetes Metab Res Rev. 2010 May; 26(4):306-18. Davidson EP, Coppey LJ, Calcutt NA, Oltman CL, Yorek MA. PMID: 20503263; PMCID: PMC2878284.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
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    67. Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment. Diabetes. 2010 Apr; 59(4):1082-91. Chowdhury SK, Zherebitskaya E, Smith DR, Akude E, Chattopadhyay S, Jolivalt CG, Calcutt NA, Fernyhough P. PMID: 20103706; PMCID: PMC2844817.
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    71. Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. Nat Rev Drug Discov. 2009 May; 8(5):417-29. Calcutt NA, Cooper ME, Kern TS, Schmidt AM. PMID: 19404313; PMCID: PMC7097138.
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    72. B vitamins alleviate indices of neuropathic pain in diabetic rats. Eur J Pharmacol. 2009 Jun 10; 612(1-3):41-7. Jolivalt CG, Mizisin LM, Nelson A, Cunha JM, Ramos KM, Bonke D, Calcutt NA. PMID: 19393643.
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    73. Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth. J Neurosci. 2009 Feb 04; 29(5):1277-84. Garcia ML, Rao MV, Fujimoto J, Garcia VB, Shah SB, Crum J, Gotow T, Uchiyama Y, Ellisman M, Calcutt NA, Cleveland DW. PMID: 19193875; PMCID: PMC2782950.
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    74. Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters. Pain. 2008 Nov 15; 140(1):48-57. Jolivalt CG, Lee CA, Ramos KM, Calcutt NA. PMID: 18755547; PMCID: PMC2593464.
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    75. Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice. Neurosci Lett. 2008 Sep 19; 442(3):267-72. Beiswenger KK, Calcutt NA, Mizisin AP. PMID: 18619518; PMCID: PMC2610845.
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    76. Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors. Metabolism. 2008 Jul; 57(7):873-81. Cunha JM, Jolivalt CG, Ramos KM, Gregory JA, Calcutt NA, Mizisin AP. PMID: 18555826; PMCID: PMC2518323.
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    77. Impaired prosaposin secretion during nerve regeneration in diabetic rats and protection of nerve regeneration by a prosaposin-derived peptide. J Neuropathol Exp Neurol. 2008 Jul; 67(7):702-10. Jolivalt CG, Vu Y, Mizisin LM, Mizisin AP, Calcutt NA. PMID: 18596543; PMCID: PMC2748883.
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    78. Epidermal nerve fiber quantification in the assessment of diabetic neuropathy. Acta Histochem. 2008; 110(5):351-62. Beiswenger KK, Calcutt NA, Mizisin AP. PMID: 18384843; PMCID: PMC2561960.
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    79. The pathological interaction between diabetes and presymptomatic Alzheimer's disease. Neurobiol Aging. 2009 Dec; 30(12):1910-7. Burdo JR, Chen Q, Calcutt NA, Schubert D. PMID: 18372080.
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    80. Growth factors as therapeutics for diabetic neuropathy. Curr Drug Targets. 2008 Jan; 9(1):47-59. Calcutt NA, Jolivalt CG, Fernyhough P. PMID: 18220712.
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    81. Pathogenesis of pain in peripheral diabetic neuropathy. Curr Diab Rep. 2007 Dec; 7(6):429-34. Calcutt NA, Backonja MM. PMID: 18255005.
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    83. Central action of prosaptide TX14(A) against gp120-induced allodynia in rats. Eur J Pain. 2008 Jan; 12(1):76-81. Jolivalt CG, Dacunha JM, Esch FS, Calcutt NA. PMID: 17466547.
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    84. Pathogenesis of spinally mediated hyperalgesia in diabetes. Diabetes. 2007 Jun; 56(6):1569-76. Ramos KM, Jiang Y, Svensson CI, Calcutt NA. PMID: 17287466.
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    85. Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats. J Peripher Nerv Syst. 2006 Dec; 11(4):274-85. Jiang Y, Calcutt NA, Ramos KM, Rames KM, Mizisin AP. PMID: 17117935.
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    86. Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats. Brain Res. 2006 Oct 18; 1115(1):48-53. Malmberg AB, O'Connor WT, Glennon JC, Ceseña R, Calcutt NA. PMID: 16920081.
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    87. Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats. Diabetologia. 2006 Nov; 49(11):2775-85. Jolivalt CG, Jiang Y, Freshwater JD, Bartoszyk GD, Calcutt NA. PMID: 16924480.
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    88. Protection of sensory function in diabetic rats by Neotrofin. Eur J Pharmacol. 2006 Mar 18; 534(1-3):187-93. Calcutt NA, Freshwater JD, Hauptmann N, Taylor EM, Mizisin AP. PMID: 16507305.
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    89. Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia. Pain. 2006 Mar; 121(1-2):14-21. Jolivalt CG, Ramos KM, Herbetsson K, Esch FS, Calcutt NA. PMID: 16480831.
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    90. Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch. Pain. 2004 Oct; 111(3):360-367. Malmberg AB, Mizisin AP, Calcutt NA, von Stein T, Robbins WR, Bley KR. PMID: 15363880.
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    91. Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration deficits in diabetic rats. Diabetes. 2004 Jul; 53(7):1807-12. Mizisin AP, Vu Y, Shuff M, Calcutt NA. PMID: 15220205.
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    92. Experimental models of painful diabetic neuropathy. J Neurol Sci. 2004 May 15; 220(1-2):137-9. Calcutt NA. PMID: 15140623.
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    93. Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor. Diabetologia. 2004 Apr; 47(4):718-24. Calcutt NA, Freshwater JD, Mizisin AP. PMID: 15298349.
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    94. Modeling diabetic sensory neuropathy in rats. Methods Mol Med. 2004; 99:55-65. Calcutt NA. PMID: 15131329.
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    95. NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth. J Cell Biol. 2003 Dec 08; 163(5):1011-20. Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, Ward CM, Crawford TO, Gotow T, Uchiyama Y, Ellisman MH, Calcutt NA, Cleveland DW. PMID: 14662745; PMCID: PMC2173620.
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    96. Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. J Neurochem. 2003 Sep; 86(6):1534-44. Svensson CI, Marsala M, Westerlund A, Calcutt NA, Campana WM, Freshwater JD, Catalano R, Feng Y, Protter AA, Scott B, Yaksh TL. PMID: 12950462.
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    97. Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats. Diabetes. 2003 Sep; 52(9):2372-80. Sayers NM, Beswick LJ, Middlemas A, Calcutt NA, Mizisin AP, Tomlinson DR, Fernyhough P. PMID: 12941778.
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    98. Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia. Diabetes. 2003 Aug; 52(8):2129-36. Huang TJ, Price SA, Chilton L, Calcutt NA, Tomlinson DR, Verkhratsky A, Fernyhough P. PMID: 12882932.
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    99. Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy. J Clin Invest. 2003 Feb; 111(4):507-14. Calcutt NA, Allendoerfer KL, Mizisin AP, Middlemas A, Freshwater JD, Burgers M, Ranciato R, Delcroix JD, Taylor FR, Shapiro R, Strauch K, Dudek H, Engber TM, Galdes A, Rubin LL, Tomlinson DR. PMID: 12588889; PMCID: PMC151919.
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    100. Future treatments for diabetic neuropathy: clues from experimental neuropathy. Curr Diab Rep. 2002 Dec; 2(6):482-8. Calcutt NA. PMID: 12643154.
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    101. Injury type-specific calcium channel alpha 2 delta-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin. J Pharmacol Exp Ther. 2002 Dec; 303(3):1199-205. Luo ZD, Calcutt NA, Higuera ES, Valder CR, Song YH, Svensson CI, Myers RR. PMID: 12438544.
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    102. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J Cell Biol. 2002 Aug 19; 158(4):681-93. Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW. PMID: 12186852; PMCID: PMC2174004.
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    103. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes. 2002 Jul; 51(7):2249-55. Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA. PMID: 12086957.
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    104. Potential mechanisms of neuropathic pain in diabetes. Int Rev Neurobiol. 2002; 50:205-28. Calcutt NA. PMID: 12198811.
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    105. TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats. J Neuropathol Exp Neurol. 2001 Oct; 60(10):953-60. Mizisin AP, Steinhardt RC, O'Brien JS, Calcutt NA. PMID: 11589426.
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    106. Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury. Muscle Nerve. 2001 Jun; 24(6):799-808. Rende M, Brizi E, Donato R, Provenzano C, Bruno R, Mizisin AP, Garrett RS, Calcutt NA, Campana WM, O'Brien JS. PMID: 11360264.
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    107. Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats. Anesthesiology. 2000 Nov; 93(5):1271-8. Calcutt NA, Freshwater JD, O'Brien JS. PMID: 11046216.
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    108. Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo. J Peripher Nerv Syst. 2000 Sep; 5(3):126-30. Campana WM, Mohiuddin L, Misasi R, O'Brien JS, Calcutt NA. PMID: 11442168.
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    109. Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats. Brain Res. 2000 Feb 21; 856(1-2):20-7. Calcutt NA, Stiller C, Gustafsson H, Malmberg AB. PMID: 10677607.
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    110. Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development. J Neurosci. 1999 Nov 01; 19(21):9201-8. Luo ZD, Chaplan SR, Scott BP, Cizkova D, Calcutt NA, Yaksh TL. PMID: 10531423; PMCID: PMC6782898.
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    111. Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats. J Neuropathol Exp Neurol. 1999 Jun; 58(6):628-36. Calcutt NA, Campana WM, Eskeland NL, Mohiuddin L, Dines KC, Mizisin AP, O'Brien JS. PMID: 10374753.
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    112. Gabapentin prevents hyperalgesia during the formalin test in diabetic rats. Neurosci Lett. 1999 Mar 05; 262(2):101-4. Ceseña RM, Calcutt NA. PMID: 10203241.
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    113. Necrotizing myopathy induced by overexpression of interferon-gamma in transgenic mice. Muscle Nerve. 1999 Feb; 22(2):156-65. Shelton GD, Calcutt NA, Garrett RS, Gu D, Sarvetnick N, Campana WM, Powell HC. PMID: 10024128.
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    114. Effects of hindlimb temperature on sciatic nerve laser Doppler vascular conductance in control and streptozotocin-diabetic rats. J Neurol Sci. 1999 Feb 01; 163(1):17-24. Dines KC, Calcutt NA, Nunag KD, Mizisin AP, Kalichman MW. PMID: 10223405.
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    115. Neurotrophin-3 reverses nerve conduction velocity deficits in streptozotocin-diabetic rats. J Peripher Nerv Syst. 1999; 4(3-4):211-21. Mizisin AP, Calcutt NA, Tomlinson DR, Gallagher A, Fernyhough P. PMID: 10642089.
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    116. Effects of diabetes on tissue content and evoked release of calcitonin gene-related peptide-like immunoreactivity from rat sensory nerves. Neurosci Lett. 1998 Oct 02; 254(3):129-32. Calcutt NA, Chen P, Hua XY. PMID: 10214974.
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    117. Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice. Diabetes. 1998 Jun; 47(6):961-6. Ng TF, Lee FK, Song ZT, Calcutt NA, Lee AY, Chung SS, Chung SK, Ng DT, Lee LW. PMID: 9604875.
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    118. Effects of the peptide HP228 on nerve disorders in diabetic rats. Metabolism. 1998 Jun; 47(6):650-6. Calcutt NA, Dines KC, Ceseña RM. PMID: 9627361.
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    119. Prosaptide prevents paclitaxel neurotoxicity. Neurotoxicology. 1998 Apr; 19(2):237-44. Campana WM, Eskeland N, Calcutt NA, Misasi R, Myers RR, O'Brien JS. PMID: 9553960.
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    120. Spinal pharmacology of tactile allodynia in diabetic rats. Br J Pharmacol. 1997 Dec; 122(7):1478-82. Calcutt NA, Chaplan SR. PMID: 9421298; PMCID: PMC1565094.
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    121. BDNF attenuates functional and structural disorders in nerves of galactose-fed rats. J Neuropathol Exp Neurol. 1997 Dec; 56(12):1290-301. Mizisin AP, Bache M, DiStefano PS, Acheson A, Lindsay RM, Calcutt NA. PMID: 9413278.
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    122. Neonatal capsaicin treatment abolishes formalin-induced spinal PGE2 release. Neuroreport. 1997 Jul 07; 8(9-10):2325-9. Hua XY, Calcutt NA, Malmberg AB. PMID: 9243634.
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    123. Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells. Neurosci Lett. 1997 Jun 20; 229(1):53-6. Mizisin AP, Li L, Calcutt NA. PMID: 9224800.
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    124. Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves from galactose-fed and normal rats. Diabetes. 1997 Apr; 46(4):647-52. Mizisin AP, Calcutt NA, DiStefano PS, Acheson A, Longo FM. PMID: 9075806.
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    125. The effect of alpha-trinositol (D-myo-inositol 1,2,6-trisphosphate) on formalin-evoked spinal amino acid and prostaglandin E2 levels. Brain Res. 1997 Jan 30; 747(1):160-4. Malmberg AB, Hedner T, Fallgren B, Calcutt NA. PMID: 9042542.
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    127. Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. Pain. 1996 Dec; 68(2-3):293-9. Calcutt NA, Jorge MC, Yaksh TL, Chaplan SR. PMID: 9121817.
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    128. Effects of seven days of galactose feeding and aldose reductase inhibition on mast cells and vessel morphometry in rat sciatic nerve. J Neurol Sci. 1996 Sep 15; 141(1-2):6-12. Brett FM, Kalichman MW, Calcutt NA, Mizisin AP. PMID: 8880685.
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    129. Enteric neuropeptides in streptozotocin-diabetic rats; effects of insulin and aldose reductase inhibition. J Auton Nerv Syst. 1996 May 06; 58(3):163-9. Belai A, Calcutt NA, Carrington AL, Diemel LT, Tomlinson DR, Burnstock G. PMID: 8738309.
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    130. Polyol pathway and osmoregulation in JS1 Schwann cells grown in hyperglycemic and hyperosmotic conditions. Am J Physiol. 1996 Jan; 270(1 Pt 2):F90-7. Mizisin AP, Li L, Perello M, Freshwater JD, Kalichman MW, Roux L, Calcutt NA. PMID: 8769826.
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    132. Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction. J Exp Med. 1995 Feb 01; 181(2):547-57. Gu D, Wogensen L, Calcutt NA, Xia C, Zhu S, Merlie JP, Fox HS, Lindstrom J, Powell HC, Sarvetnick N. PMID: 7836911; PMCID: PMC2191877.
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    135. Inhibition of macrophage chemotaxis and peripheral nerve regeneration in normal and hyperglycemic rats by the aldose reductase inhibitor Tolrestat. Exp Neurol. 1994 Aug; 128(2):226-32. Calcutt NA, McMurray HF, Moorhouse DF, Bache M, Parthasarathy S, Powell HC, Mizisin AP. PMID: 8076666.
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    146. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun; 34(6):397-401. Carrington AL, Ettlinger CB, Calcutt NA, Tomlinson DR. PMID: 1653157.
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    147. Resistance to hypoxic conduction block in sciatic nerves of rats with streptozotocin-induced diabetes mellitus. J Neurol Sci. 1991 May; 103(1):116-23. Calcutt NA, Ettlinger CB, Carrington AL, Diemel L, Tomlinson DR. PMID: 1865225.
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    148. Coexistence of nerve conduction deficit with increased Na(+)-K(+)-ATPase activity in galactose-fed mice. Implications for polyol pathway and diabetic neuropathy. Diabetes. 1990 Jun; 39(6):663-6. Calcutt NA, Tomlinson DR, Biswas S. PMID: 2161366.
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    149. Axonal transport of substance P-like immunoreactivity in ganglioside-treated diabetic rats. J Neurol Sci. 1990 May; 96(2-3):283-91. Calcutt NA, Tomlinson DR, Willars GB, Keen P. PMID: 1695917.
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    150. Substance P levels in peripheral nerve, skin, atrial myocardium and gastrointestinal tract of rats with long-term diabetes mellitus. Effects of aldose reductase inhibition. J Neurol Sci. 1989 Jun; 91(1-2):153-64. Willars GB, Calcutt NA, Compton AM, Tomlinson DR, Keen P. PMID: 2473171.
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    151. Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris. Curr Eye Res. 1989 Apr; 8(4):357-63. Tomlinson DR, Willars GB, Calcutt NA, Compton AM, Macdonald IA, Clarke HE, Keen P. PMID: 2470551.
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    152. Axonal transport of choline acetyltransferase and 6-phosphofructokinase activities in genetically diabetic mice. Muscle Nerve. 1988 Dec; 11(12):1206-10. Calcutt NA, Willars GB, Tomlinson DR. PMID: 2467203.
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    153. Adenosine triphosphatase in nerves and ganglia of rats with streptozotocin-induced diabetes or galactosaemia; effects of aldose reductase inhibition. Diabetologia. 1988 Jun; 31(6):379-84. Lambourne JE, Brown AM, Calcutt N, Tomlinson DR, Willars GB. PMID: 2970984.
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    154. Ganglioside treatment of streptozotocin-diabetic rats prevents defective axonal transport of 6-phosphofructokinase activity. J Neurochem. 1988 May; 50(5):1478-83. Calcutt NA, Tomlinson DR, Willars GB. PMID: 2452237.
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    155. Statil-sensitive polyol formation in nerve of galactose-fed mice. Metabolism. 1988 May; 37(5):450-3. Calcutt NA, Willars GB, Tomlinson DR. PMID: 3130544.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    156. Ganglioside treatment of diabetic rats; effects on nerve adenosine triphosphatase activity and motor nerve conduction velocity. Life Sci. 1988; 42(16):1515-20. Calcutt NA, Tomlinson DR, Willars GB. PMID: 2965293.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    157. Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue. J Neurol Neurosurg Psychiatry. 1987 Jun; 50(6):775-8. Godridge H, Reynolds GP, Czudek C, Calcutt NA, Benton M. PMID: 2440994; PMCID: PMC1032086.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    158. Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor 'Statil'. Diabetologia. 1987 Apr; 30(4):239-43. Willars GB, Calcutt NA, Tomlinson DR. PMID: 2439402.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
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