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Michael Bouvet

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9500 Gilman Drive #0987
La Jolla CA 92093
Phone858-822-6191
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    Collapse Overview 
    Collapse Overview
    Dr. Michael Bouvet specializes in surgical oncology and endocrine surgery. He performs surgeries for tumors of the pancreas, thyroid, parathyroid, adrenal, esophagus, and stomach, as well as for other conditions. He is also a specialist in endocrine surgery, including surgery for thyroid nodules and thyroid cancer, minimally invasive parathyroidectomy for primary hyperparathyroidism, and laparoscopic adrenal surgery. He is a member of the American Association of Endocrine Surgeons, the Society of Surgical Oncologists, the American Thyroid Association, and the American College of Surgeons. Dr. Bouvet is certified by the American Board of Surgery and has been selected as one of America’s Top Surgeons by the Consumers’ Research Council of America and one of San Diego's Top Doctors.

    Dr. Bouvet has extensive training and experience in cancer surgery. He completed advanced fellowship training in surgical oncology at the renowned MD Anderson Cancer Center at the University of Texas. Here at UC San Diego, Dr. Bouvet is a key surgeon and researcher at the Moores UC San Diego Cancer Center, where he serves as Co-Director of the Specialized Gastrointestinal Cancer Care Unit, Director of Endocrine Surgery, and Director of Surgical Services.

    Dr. Bouvet specializes in endocrine and pancreatic surgery. He routinely does surgery for thyroid nodules and thyroid cancer as well as minimally invasive surgery for hyperparathyroidism. He has performed many whipple procedures for pancreatic cancer.

    In his research at UC San Diego, Dr. Bouvet conducts major investigations on the growth and spread of pancreatic cancer and the treatment of pancreatic cancer and other tumors. He is an investigator on several major National Cancer Institute-funded studies on the treatment, understanding, and monitoring of pancreatic cancer. In his recent medical publications, he reported the causes and factors that influence its growth as well as new techniques for imaging pancreatic cancer. Make a donation for pancreatic cancer research.

    Research Overview
    My research interests include the development of multi-color fluorescent orthotopic mouse models of pancreatic cancer to study the tumor microenvironment. In addition, our lab has developed tumor specific fluorescent probes that can be used to improve laparoscopic staging and complete surgical resection of GI malignancies. We also have several projects related to surgical outcomes in patients with thyroid cancer.

    • Angiogenesis

    • Cancer

    • Cell Biology

    • Endocrinology

    • Minimally Invasive Techniques

    • Outcomes


    Current Project Titles

    • Color-Coded Imaging of Pancreatic Cancer Microenvironment for Drug Discovery

    • Fluorophore-Conjugated Antibodies for Imaging and Resection of GI Tumors

    • Tumor-stroma interactions in pancreatic cancer

    • Clinical outcomes in patients with thyroid cancer



    Resources

    Conditions and Treatments



    Collapse Research 
    Collapse Research Activities and Funding
    Development of Near Infrared Fluorescence-Guided Surgical Navigation and Tumor Specific Photoimmunotherapy for Improved Outcomes for GI Cancers
    VA I01BX003856Oct 1, 2017 - Sep 30, 2021
    Role: Principal Investigator
    Fluorophore-Conjugated Antibodies for Imaging and Resection of GI Tumors
    NIH/NCI R01CA142669Jun 24, 2010 - Apr 30, 2016
    Role: Principal Investigator
    Divalent cation activation of the integrin-mediated malignant phenotype in pancre
    NIH/NCI R21CA135435Mar 1, 2009 - Feb 28, 2011
    Role: Principal Investigator
    Color-Coded Imaging of Pancreatic Cancer Microenvironment for Drug Discovery
    NIH/NCI R01CA132971Jan 1, 2009 - Dec 31, 2013
    Role: Principal Investigator
    UCSD Cancer Center Training Program in Drug Development
    NIH/NCI T32CA121938Jul 1, 2006 - Jun 30, 2021
    Role: Principal Investigator
    Imageable Mouse Models of Pancreatic Cancer
    NIH/NCI R33CA109949Sep 23, 2004 - Aug 31, 2010
    Role: Principal Investigator
    Imageable Mouse Models of Pancreatic Cancer
    NIH/NCI R21CA109949Sep 23, 2004 - Aug 31, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Tran M, Vincent L, Ho G, Kelly K, Bouvet M, Meier A. Critical Consideration of Myxedema Coma in the Postoperative Setting: A Case Report. A A Pract. 2018 Aug 29. PMID: 30169383.
      View in: PubMed
    2. Tome Y, Kiyuna T, Uehara F, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. Imaging the interaction of av integrin-GFP in osteosarcoma cells with RFP-expressing host stromal cells and tumor-scaffold collagen in the primary and metastatic tumor microenvironment. J Cell Biochem. 2018 Aug 26. PMID: 30145815.
      View in: PubMed
    3. Lwin TM, Hoffman RM, Bouvet M. Advantages of patient-derived orthotopic mouse models and genetic reporters for developing fluorescence-guided surgery. J Surg Oncol. 2018 Aug 06. PMID: 30080930.
      View in: PubMed
    4. Kawaguchi K, Miyake K, Zhao M, Kiyuna T, Igarashi K, Miyake M, Higuchi T, Oshiro H, Bouvet M, Unno M, Hoffman RM. Tumor targeting Salmonella typhimurium A1-R in combination with gemcitabine (GEM) regresses partially GEM-resistant pancreatic cancer patient-derived orthotopic xenograft (PDOX) nude mouse models. Cell Cycle. 2018 Jul 02. PMID: 29963961.
      View in: PubMed
    5. Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Kiyuna T, Miyake M, Higuchi T, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Bouvet M, Singh SR, Unno M, Hoffman RM. Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer. Cancer Lett. 2018 Jun 18; 432:251-259. PMID: 29928962.
      View in: PubMed
    6. Miyake K, Kawaguchi K, Miyake M, Zhao M, Kiyuna T, Igarashi K, Zhang Z, Murakami T, Li Y, Nelson SD, Bouvet M, Elliott I, Russell TA, Singh AS, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Singh SR, Endo I, Eilber FC, Hoffman RM. Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations. Heliyon. 2018 Jun; 4(6):e00643. PMID: 30003151.
      View in: PubMed
    7. Lwin TM, Hoffman RM, Bouvet M. The development of fluorescence guided surgery for pancreatic cancer: from bench to clinic. Expert Rev Anticancer Ther. 2018 May 16. PMID: 29768067.
      View in: PubMed
    8. Kawaguchi K, Igarashi K, Miyake K, Lwin TM, Miyake M, Kiyuna T, Hwang HK, Murakami T, Delong JC, Singh SR, Clary B, Bouvet M, Unno M, Hoffman RM. MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model. Tissue Cell. 2018 Jun; 52:124-128. PMID: 29857821.
      View in: PubMed
    9. Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Lwin TM, Higuchi T, Kiyuna T, Miyake M, Oshiro H, Bouvet M, Unno M, Hoffman RM. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer. Cell Cycle. 2018 Apr 06; 1-23. PMID: 29623758.
      View in: PubMed
    10. Sato K, Mori R, Hiroshima Y, Oba MS, Matsuyama R, Bouvet M, Hoffman RM, Endo I. RT-PCR of peritoneal washings predicts peritoneal pancreatic cancer recurrence. J Surg Res. 2018 Jun; 226:122-130. PMID: 29661277.
      View in: PubMed
    11. Hwang HK, Kang CM, Lee SH, Murakami T, Kiyuna T, Kim SH, Hoffman RM, Bouvet M. Fluorescence-guided Surgery with Splenic Preservation Prevents Tumor Recurrence in an Orthotopic Nude-mouse Model of Human Pancreatic Cancer. Anticancer Res. 2018 02; 38(2):665-670. PMID: 29374688.
      View in: PubMed
    12. Lwin TM, Murakami T, Miyake K, Yazaki PJ, Shivley JE, Hoffman RM, Bouvet M. Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore. Ann Surg Oncol. 2018 Apr; 25(4):1079-1085. PMID: 29372363.
      View in: PubMed
    13. DeLong JC, Ward EP, Lwin TM, Brumund KT, Kelly KJ, Horgan S, Bouvet M. Indocyanine green fluorescence-guided parathyroidectomy for primary hyperparathyroidism. Surgery. 2018 Feb; 163(2):388-392. PMID: 29129358.
      View in: PubMed
    14. DeLong JC, Murakami T, Yazaki PJ, Hoffman RM, Bouvet M. Near-infrared-conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude-mouse model. J Surg Res. 2017 Oct; 218:139-143. PMID: 28985840.
      View in: PubMed
    15. Hwang HK, Murakami T, Kiyuna T, Kim SH, Lee SH, Kang CM, Hoffman RM, Bouvet M. Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model. Oncotarget. 2017 Oct 24; 8(51):88827-88834. PMID: 29179479.
      View in: PubMed
    16. Lwin TM, Hoffman RM, Bouvet M. Regarding the applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy. Transl Gastroenterol Hepatol. 2017; 2:70. PMID: 29034343.
      View in: PubMed
    17. Miyake K, Murakami T, Kiyuna T, Igarashi K, Kawaguchi K, Miyake M, Li Y, Nelson SD, Dry SM, Bouvet M, Elliott IA, Russell TA, Singh AS, Eckardt MA, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Endo I, Eilber FC, Hoffman RM. The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy. Oncotarget. 2017 Nov 28; 8(61):103129-103136. PMID: 29262551.
      View in: PubMed
    18. Murakami T, Hiroshima Y, Zhang Y, Zhao M, Kiyuna T, Hwang HK, Miyake K, Homma Y, Mori R, Matsuyama R, Chishima T, Ichikawa Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. Tumor-Targeting Salmonella typhimurium A1-R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic-Cancer Orthotopic Mouse Model. J Cell Biochem. 2018 Jan; 119(1):634-639. PMID: 28628234.
      View in: PubMed
    19. Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Lwin TM, Hwang HK, Delong JC, Clary BM, Bouvet M, Unno M, Hoffman RM. MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX). Oncotarget. 2017 Jul 18; 8(29):47490-47496. PMID: 28537897.
      View in: PubMed
    20. Tipirneni KE, Warram JM, Moore LS, Prince AC, de Boer E, Jani AH, Wapnir IL, Liao JC, Bouvet M, Behnke NK, Hawn MT, Poultsides GA, Vahrmeijer AL, Carroll WR, Zinn KR, Rosenthal E. Oncologic Procedures Amenable to Fluorescence-guided Surgery. Ann Surg. 2017 07; 266(1):36-47. PMID: 28045715.
      View in: PubMed
    21. Murakami T, Homma Y, Matsuyama R, Mori R, Miyake K, Tanaka Y, Den K, Nagashima Y, Nakazawa M, Hiroshima Y, Ueda M, Tanaka K, Hoffman RM, Bouvet M, Endo I. Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I-related chain A/B expression. J Surg Oncol. 2017 Sep; 116(3):416-426. PMID: 28608409.
      View in: PubMed
    22. Murakami T, Li S, Han Q, Tan Y, Kiyuna T, Igarashi K, Kawaguchi K, Hwang HK, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Hiroshima Y, Lwin TM, DeLong JC, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2017 May 30; 8(22):35630-35638. PMID: 28404944.
      View in: PubMed
    23. King J, Bouvet M, Singh G, Williams J. Improving theranostics in pancreatic cancer. J Surg Oncol. 2017 Jul; 116(1):104-113. PMID: 28513912.
      View in: PubMed
    24. Murakami T, Hiroshima Y, Miyake K, Hwang HK, Kiyuna T, DeLong JC, Lwin TM, Matsuyama R, Mori R, Kumamoto T, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. Color-coded intravital imaging demonstrates a transforming growth factor-ß (TGF-ß) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model. Cell Cycle. 2017 May 19; 16(10):1008-1014. PMID: 28441080.
      View in: PubMed
    25. Tummers WS, Warram JM, Tipirneni KE, Fengler J, Jacobs P, Shankar L, Henderson L, Ballard B, Pogue BW, Weichert JP, Bouvet M, Sorger J, Contag CH, Frangioni JV, Tweedle MF, Basilion JP, Gambhir SS, Rosenthal EL. Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection. Cancer Res. 2017 05 01; 77(9):2197-2206. PMID: 28428283.
      View in: PubMed
    26. Strnadel J, Choi S, Fujimura K, Wang H, Zhang W, Wyse M, Wright T, Gross E, Peinado C, Park HW, Bui J, Kelber J, Bouvet M, Guan KL, Klemke RL. eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth. Cancer Res. 2017 04 15; 77(8):1997-2007. PMID: 28381547.
      View in: PubMed
    27. Kawaguchi K, Murakami T, Suetsugu A, Kiyuna T, Igarashi K, Hiroshima Y, Zhao M, Zhang Y, Bouvet M, Clary BM, Unno M, Hoffman RM. High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. Oncotarget. 2017 Mar 21; 8(12):19065-19073. PMID: 27683127.
      View in: PubMed
    28. Murakami T, Kiyuna T, Kawaguchi K, Igarashi K, Singh AS, Hiroshima Y, Zhang Y, Zhao M, Miyake K, Nelson SD, Dry SM, Li Y, DeLong JC, Lwin TM, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago. Cell Cycle. 2017 Jun 03; 16(11):1046-1052. PMID: 28296559.
      View in: PubMed
    29. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture. In Vitro Cell Dev Biol Anim. 2017 Jun; 53(6):479-482. PMID: 28233141.
      View in: PubMed
    30. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro. In Vitro Cell Dev Biol Anim. 2017 Apr; 53(4):285-287. PMID: 28127701.
      View in: PubMed
    31. Hoover M, Adamian Y, Brown M, Maawy A, Chang A, Lee J, Gharibi A, Katz MH, Fleming J, Hoffman RM, Bouvet M, Doebler R, Kelber JA. A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts. Oncotarget. 2017 Jan 24; 8(4):5885-5894. PMID: 27602776.
      View in: PubMed
    32. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Fujiwara T, Bouvet M, Hoffman RM. Comparison of Tumor Recurrence After Resection of Highly- and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models. Anticancer Res. 2017 01; 37(1):57-60. PMID: 28011473.
      View in: PubMed
    33. Murakami T, Murata T, Kawaguchi K, Kiyuna T, Igarashi K, Hwang HK, Hiroshima Y, Hozumi C, Komatsu S, Kikuchi T, Lwin TM, Delong JC, Miyake K, Zhang Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel. Anticancer Res. 2017 01; 37(1):61-65. PMID: 28011474.
      View in: PubMed
    34. Tome Y, Kimura H, Sugimoto N, Tsuchiya H, Kanaya F, Bouvet M, Hoffman RM. The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing a?ß3 integrin in chick embryo and nude mouse models. Oncotarget. 2016 Dec 27; 7(52):87031-87036. PMID: 27894082.
      View in: PubMed
    35. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models. Oncotarget. 2016 Dec 20; 7(51):85273-85282. PMID: 27863373.
      View in: PubMed
    36. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. In Vivo Selection of Intermediately- and Highly-Malignant Variants of Triple-negative Breast Cancer in Orthotopic Nude Mouse Models. Anticancer Res. 2016 12; 36(12):6273-6277. PMID: 27919946.
      View in: PubMed
    37. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. Oncotarget. 2016 11 15; 7(46):75635-75647. PMID: 27689331.
      View in: PubMed
    38. Hiroshima Y, Maawy A, Zhang Y, Zhang N, Murakami T, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy. Oncotarget. 2016 11 01; 7(44):71696-71702. PMID: 27765934.
      View in: PubMed
    39. Yano S, Takehara K, Tazawa H, Kishimoto H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. Enhanced Metastatic Recurrence Via Lymphatic Trafficking of a High-Metastatic Variant of Human Triple-Negative Breast Cancer After Surgical Resection in Orthotopic Nude Mouse Models. J Cell Biochem. 2017 03; 118(3):559-569. PMID: 27626220.
      View in: PubMed
    40. Hiroshima Y, Lwin TM, Murakami T, Mawy AA, Kuniya T, Chishima T, Endo I, Clary BM, Hoffman RM, Bouvet M. Effective fluorescence-guided surgery of liver metastasis using a fluorescent anti-CEA antibody. J Surg Oncol. 2016 Dec; 114(8):951-958. PMID: 27696448.
      View in: PubMed
    41. Lwin TM, Sicklick JK, Hoffinan RM, Bouvet M. Fluorescence-guided laparoscopic hepatectomy. Ann Laparosc Endosc Surg. 2016 Sep; 1. PMID: 30175321.
      View in: PubMed
    42. Fuchs HF, Harnsberger CR, Broderick RC, Chang DC, Sandler BJ, Jacobsen GR, Bouvet M, Horgan S. Mortality after esophagectomy is heavily impacted by center volume: retrospective analysis of the Nationwide Inpatient Sample. Surg Endosc. 2017 Jun; 31(6):2491-2497. PMID: 27660245.
      View in: PubMed
    43. DeLong JC, Kelly KJ, Jacobsen GR, Sandler BJ, Horgan S, Bouvet M. The benefits and limitations of robotic assisted transhiatal esophagectomy for esophageal cancer. J Vis Surg. 2016; 2:156. PMID: 29078542.
      View in: PubMed
    44. Zhang Y, Toneri M, Ma H, Yang Z, Bouvet M, Goto Y, Seki N, Hoffman RM. Real-Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude-Mouse Models of Human PC-3 Prostate Cancer. J Cell Biochem. 2016 11; 117(11):2546-51. PMID: 27012365.
      View in: PubMed
    45. Matsumoto T, Suetsugu A, Hasegawa K, Nakamura M, Shibata Y, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Bouvet M, Hoffman RM. A Mouse Model of Fluorescent Protein-expressing Disseminated Peritoneal Lymphoma for Fluorescence-guided Surgery. Anticancer Res. 2016 09; 36(9):4483-7. PMID: 27630285.
      View in: PubMed
    46. Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Kunisada T, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. Color-coded Imaging Enables Fluorescence-guided Surgery to Resect the Tumor Along with the Tumor Microenvironment in a Syngeneic Mouse Model of EL-4 Lymphoma. Anticancer Res. 2016 09; 36(9):4443-8. PMID: 27630280.
      View in: PubMed
    47. Yamamoto M, Zhao M, Hiroshima Y, Zhang Y, Shurell E, Eilber FC, Bouvet M, Noda M, Hoffman RM. Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model. PLoS One. 2016; 11(8):e0160882. PMID: 27500926; PMCID: PMC4976963.
    48. Tome Y, Yano S, Sugimoto N, Mii S, Uehara F, Miwa S, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. Use of av Integrin Linked to Green Fluorescent Protein in Osteosarcoma Cells and Confocal Microscopy to Image Molecular Dynamics During Lung Metastasis in Nude Mice. Anticancer Res. 2016 Aug; 36(8):3811-6. PMID: 27466481.
      View in: PubMed
    49. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. In Vivo Isolation of a Highly-aggressive Variant of Triple-negative Human Breast Cancer MDA-MB-231 Using Serial Orthotopic Transplantation. Anticancer Res. 2016 Aug; 36(8):3817-20. PMID: 27466482.
      View in: PubMed
    50. Tome Y, Uehara F, Miwa S, Yano S, Mii S, Efimova EV, Bouvet M, Kimura H, Tsuchiya H, Kanaya F, Hoffman RM. Efficacy of the Combination of a PARP Inhibitor and UVC on Cancer Cells as Imaged by Focus Formation by the DNA Repair-related Protein 53BP1 Linked to Green Fluorescent Protein. Anticancer Res. 2016 Aug; 36(8):3821-6. PMID: 27466483.
      View in: PubMed
    51. Suetsugu A, Matsumoto T, Hasegawa K, Nakamura M, Kunisada T, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. Color-coded Live Imaging of Heterokaryon Formation and Nuclear Fusion of Hybridizing Cancer Cells. Anticancer Res. 2016 Aug; 36(8):3827-31. PMID: 27466484.
      View in: PubMed
    52. Murakami T, Singh AS, Kiyuna T, Dry SM, Li Y, James AW, Igarashi K, Kawaguchi K, DeLong JC, Zhang Y, Hiroshima Y, Russell T, Eckardt MA, Yanagawa J, Federman N, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2016 Jul 26; 7(30):47556-47564. PMID: 27286459.
      View in: PubMed
    53. Tome Y, Kimura H, Kiyuna T, Sugimoto N, Tsuchiya H, Kanaya F, Bouvet M, Hoffman RM. Disintegrin targeting of an avß3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro. Oncotarget. 2016 07 19; 7(29):46315-46320. PMID: 27331872.
      View in: PubMed
    54. Tome Y, Yano S, Sugimoto N, Mii S, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. Use of av Integrin Linked to GFP to Image Molecular Dynamics in Trafficking Cancer-Cell Emboli. J Cell Biochem. 2017 01; 118(1):26-30. PMID: 27191371.
      View in: PubMed
    55. Kiyuna T, Murakami T, Tome Y, Kawaguchi K, Igarashi K, Zhang Y, Zhao M, Li Y, Bouvet M, Kanaya F, Singh A, Dry S, Eilber FC, Hoffman RM. High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model. Oncotarget. 2016 May 31; 7(22):33046-54. PMID: 27105519.
      View in: PubMed
    56. Kaneda MM, Cappello P, Nguyen AV, Ralainirina N, Hardamon CR, Foubert P, Schmid MC, Sun P, Mose E, Bouvet M, Lowy AM, Valasek MA, Sasik R, Novelli F, Hirsch E, Varner JA. Macrophage PI3K? Drives Pancreatic Ductal Adenocarcinoma Progression. Cancer Discov. 2016 08; 6(8):870-85. PMID: 27179037.
      View in: PubMed
    57. Yano S, Takehara K, Zhao M, Tan Y, Han Q, Li S, Bouvet M, Fujiwara T, Hoffman RM. Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging. Cell Cycle. 2016 Jul 02; 15(13):1715-23. PMID: 27152859; PMCID: PMC4957602 [Available on 05/06/17].
    58. Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Aoki H, Kunisada T, Bouvet M, Shimizu M, Hoffman RM. Imaging Nuclear-Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice. Anticancer Res. 2016 May; 36(5):2113-7. PMID: 27127111.
      View in: PubMed
    59. Murakami T, Zhang Y, Wang X, Hiroshima Y, Kasashima H, Yashiro M, Hirakawa K, Miwa A, Kiyuna T, Matsuyama R, Tanaka K, Bouvet M, Endo I, Hoffman RM. Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging. Anticancer Res. 2016 May; 36(5):2125-30. PMID: 27127113.
      View in: PubMed
    60. Yano S, Takehara K, Kishimoto H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models. Oncotarget. 2016 Apr 05; 7(14):18558-72. PMID: 26701857; PMCID: PMC4951309.
    61. Park JY, Lee JY, Zhang Y, Hoffman RM, Bouvet M. Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models. Oncotarget. 2016 Apr 05; 7(14):18262-8. PMID: 26919100; PMCID: PMC4951286.
    62. Fuchs HF, Broderick RC, Harnsberger CR, Divo FA, Coker AM, Jacobsen GR, Sandler BJ, Bouvet M, Horgan S. Intraoperative Endoscopic Botox Injection During Total Esophagectomy Prevents the Need for Pyloromyotomy or Dilatation. J Laparoendosc Adv Surg Tech A. 2016 Jun; 26(6):433-8. PMID: 27043862.
      View in: PubMed
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    138. Metildi CA, Kaushal S, Luiken GA, Talamini MA, Hoffman RM, Bouvet M. Fluorescently labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model. J Surg Oncol. 2014 Apr; 109(5):451-8. PMID: 24249594; PMCID: PMC3962702.
    139. Hiroshima Y, Maawy A, Sato S, Murakami T, Uehara F, Miwa S, Yano S, Momiyama M, Chishima T, Tanaka K, Bouvet M, Endo I, Hoffman RM. Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice. J Surg Res. 2014 Apr; 187(2):510-7. PMID: 24373959; PMCID: PMC3959586.
    140. Kishimoto H, Momiyama M, Aki R, Kimura H, Suetsugu A, Bouvet M, Fujiwara T, Hoffman RM. Development of a clinically-precise mouse model of rectal cancer. PLoS One. 2013; 8(11):e79453. PMID: 24265772; PMCID: PMC3827128.
    141. Suetsugu A, Jiang P, Moriwaki H, Saji S, Bouvet M, Hoffman RM. Imaging nuclear - cytoplasm dynamics of cancer cells in the intravascular niche of live mice. Anticancer Res. 2013 Oct; 33(10):4229-36. PMID: 24122986.
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    142. Tome Y, Kimura H, Maehara H, Sugimoto N, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. High lung-metastatic variant of human osteosarcoma cells, selected by passage of lung metastasis in nude mice, is associated with increased expression of a(v)ß(3) integrin. Anticancer Res. 2013 Sep; 33(9):3623-7. PMID: 24023288.
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    143. Zhang L, Wu C, Zhang Y, Liu F, Zhao M, Bouvet M, Hoffman RM. Efficacy comparison of traditional Chinese medicine LQ versus gemcitabine in a mouse model of pancreatic cancer. J Cell Biochem. 2013 Sep; 114(9):2131-7. PMID: 23553901.
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    144. Metildi CA, Tang CM, Kaushal S, Leonard SY, Magistri P, Tran Cao HS, Hoffman RM, Bouvet M, Sicklick JK. In vivo fluorescence imaging of gastrointestinal stromal tumors using fluorophore-conjugated anti-KIT antibody. Ann Surg Oncol. 2013 Dec; 20 Suppl 3:S693-700. PMID: 23943029; PMCID: PMC4127988.
    145. Hiroshima Y, Zhao M, Zhang Y, Maawy A, Hassanein MK, Uehara F, Miwa S, Yano S, Momiyama M, Suetsugu A, Chishima T, Tanaka K, Bouvet M, Endo I, Hoffman RM. Comparison of efficacy of Salmonella typhimurium A1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells. Cell Cycle. 2013 Sep 01; 12(17):2774-80. PMID: 23966167; PMCID: PMC3899191.
    146. Uehara F, Tome Y, Reynoso J, Mii S, Yano S, Miwa S, Bouvet M, Maehara H, Kanaya F, Moossa AR, Hoffman RM. Color-coded imaging of spontaneous vessel anastomosis in vivo. Anticancer Res. 2013 Aug; 33(8):3041-5. PMID: 23898058.
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    147. Snyder CS, Harrington AR, Kaushal S, Mose E, Lowy AM, Hoffman RM, Bouvet M. A dual-color genetically engineered mouse model for multispectral imaging of the pancreatic microenvironment. Pancreas. 2013 Aug; 42(6):952-8. PMID: 23648841.
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    148. Tome Y, Sugimoto N, Yano S, Momiyama M, Mii S, Maehara H, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. Real-time imaging of av integrin molecular dynamics in osteosarcoma cells in vitro and in vivo. Anticancer Res. 2013 Aug; 33(8):3021-5. PMID: 23898055.
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    149. Metildi CA, Kaushal S, Hoffman RM, Bouvet M. In vivo serial selection of human pancreatic cancer cells in orthotopic mouse models produces high metastatic variants irrespective of Kras status. J Surg Res. 2013 Sep; 184(1):290-8. PMID: 23590868; PMCID: PMC3724759.
    150. Miwa S, Tome Y, Yano S, Hiroshima Y, Uehara F, Mii S, Kimura H, Hayashi K, Tsuchiya H, Bouvet M, Efimova EV, Hoffman RM. Single cell time-lapse imaging of focus formation by the DNA damage-response protein 53BP1 after UVC irradiation of human pancreatic cancer cells. Anticancer Res. 2013 Apr; 33(4):1373-7. PMID: 23564775.
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    151. Bouvet M, Sicklick JK. Management of abdominal malignancies: updates from the International Association of Surgeons, Gastroenterologists and Oncologists. Expert Rev Anticancer Ther. 2013 Apr; 13(4):395-7. PMID: 23560834.
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    152. Momiyama M, Suetsugu A, Kimura H, Chishima T, Bouvet M, Endo I, Hoffman RM. Dynamic subcellular imaging of cancer cell mitosis in the brain of live mice. Anticancer Res. 2013 Apr; 33(4):1367-71. PMID: 23564774.
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    153. Uehara F, Tome Y, Yano S, Miwa S, Mii S, Hiroshima Y, Bouvet M, Maehara H, Kanaya F, Hoffman RM. A color-coded imaging model of the interaction of av integrin-GFP expressed in osteosarcoma cells and RFP expressing blood vessels in Gelfoam® vascularized in vivo. Anticancer Res. 2013 Apr; 33(4):1361-6. PMID: 23564773.
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    154. Metildi CA, Hoffman RM, Bouvet M. Fluorescence-guided surgery and fluorescence laparoscopy for gastrointestinal cancers in clinically-relevant mouse models. Gastroenterol Res Pract. 2013; 2013:290634. PMID: 23533387; PMCID: PMC3590746.
    155. Momiyama M, Suetsugu A, Kimura H, Kishimoto H, Aki R, Yamada A, Sakurada H, Chishima T, Bouvet M, Endo I, Hoffman RM. Imaging the efficacy of UVC irradiation on superficial brain tumors and metastasis in live mice at the subcellular level. J Cell Biochem. 2013 Feb; 114(2):428-34. PMID: 22961687.
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    156. Momiyama M, Hiroshima Y, Suetsugu A, Tome Y, Mii S, Yano S, Bouvet M, Chishima T, Endo I, Hoffman RM. Enhanced resection of orthotopic red-fluorescent-protein-expressing human glioma by fluorescence-guided surgery in nude mice. Anticancer Res. 2013 Jan; 33(1):107-11. PMID: 23267134.
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    157. Tome Y, Zhang Y, Momiyama M, Maehara H, Kanaya F, Tomita K, Tsuchiya H, Bouvet M, Hoffman RM, Zhao M. Primer dosing of S. typhimurium A1-R potentiates tumor-targeting and efficacy in immunocompetent mice. Anticancer Res. 2013 Jan; 33(1):97-102. PMID: 23267132.
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    158. Momiyama M, Suetsugu A, Chishima T, Bouvet M, Endo I, Hoffman RM. Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. Anticancer Res. 2013 Jan; 33(1):103-6. PMID: 23267133.
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    159. Uchugonova A, Zhao M, Weinigel M, Zhang Y, Bouvet M, Hoffman RM, König K. Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer-cell anchorage and shape. J Cell Biochem. 2013 Jan; 114(1):99-102. PMID: 22886742.
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    160. Momiyama M, Suetsugu A, Kimura H, Kishimoto H, Aki R, Yamada A, Sakurada H, Chishima T, Bouvet M, Bulgakova NN, Endo I, Hoffman RM. Fluorescent proteins enhance UVC PDT of cancer cells. Anticancer Res. 2012 Oct; 32(10):4327-30. PMID: 23060554.
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    161. Metildi CA, Kaushal S, Snyder CS, Hoffman RM, Bouvet M. Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model. J Surg Res. 2013 Jan; 179(1):87-93. PMID: 23079571; PMCID: PMC3518733.
    162. Menen RS, Kaushal S, Snyder CS, Talamini MA, Hoffman RM, Bouvet M. Detection of colon cancer metastases with fluorescence laparoscopy in orthotopic nude mouse models. Arch Surg. 2012 Sep; 147(9):876-80. PMID: 22987187.
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    163. Tran Cao HS, Kaushal S, Metildi CA, Menen RS, Lee C, Snyder CS, Messer K, Pu M, Luiken GA, Talamini MA, Hoffman RM, Bouvet M. Tumor-specific fluorescence antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer. Hepatogastroenterology. 2012 Sep; 59(118):1994-9. PMID: 22369743; PMCID: PMC4096574.
    164. Johnston LE, Tran Cao HS, Chang DC, Bouvet M. Sociodemographic Predictors of Survival in Differentiated Thyroid Cancer: Results from the SEER Database. ISRN Endocrinol. 2012; 2012:384707. PMID: 22957267; PMCID: PMC3431073.
    165. Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Saji S, Moriwaki H, Bouvet M, Hoffman RM. Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice. Anticancer Res. 2012 Aug; 32(8):3063-7. PMID: 22843874.
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    166. Baldassarre RL, Chang DC, Brumund KT, Bouvet M. Predictors of hypocalcemia after thyroidectomy: results from the nationwide inpatient sample. ISRN Surg. 2012; 2012:838614. PMID: 22844618; PMCID: PMC3403163.
    167. Menen RS, Hassanein MK, Momiyama M, Suetsugu A, Moossa AR, Hoffman RM, Bouvet M. Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer. In Vivo. 2012 Jul-Aug; 26(4):565-9. PMID: 22773569.
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    168. Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Moriwaki H, Bouvet M, Saji S, Hoffman RM. Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens. J Cell Biochem. 2012 Jul; 113(7):2290-5. PMID: 22573550; PMCID: PMC3566777.
    169. Menen R, Zhao M, Zhang L, Hassanein MK, Bobek V, Kolostova K, Bouvet M, Hoffman RM. Comparative chemosensitivity of circulating human prostate cancer cells and primary cancer cells. Anticancer Res. 2012 Jul; 32(7):2881-4. PMID: 22753751.
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    170. Metildi CA, Kaushal S, Hardamon CR, Snyder CS, Pu M, Messer KS, Talamini MA, Hoffman RM, Bouvet M. Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in orthotopic mouse models. J Am Coll Surg. 2012 Jul; 215(1):126-35; discussion 135-6. PMID: 22632917; PMCID: PMC3383387.
    171. Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL. KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer. Cancer Res. 2012 May 15; 72(10):2554-64. PMID: 22589274; PMCID: PMC3366503.
    172. Menen R, Pinney E, Hassanein MK, Kolostova K, Bobek V, Suetsugu A, Zhang N, Bouvet M, Naughton GK, Hoffman RM. Inhibition of metastasis of circulating human prostate cancer cells in the chick embryo by an extracellular matrix produced by foreskin fibroblasts in culture. Anticancer Res. 2012 May; 32(5):1573-7. PMID: 22593434.
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    173. Metildi CA, Kaushal S, Lee C, Hardamon CR, Snyder CS, Luiken GA, Talamini MA, Hoffman RM, Bouvet M. An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models. J Am Coll Surg. 2012 Jun; 214(6):997-1007.e2. PMID: 22542065; PMCID: PMC3360832.
    174. Tran Cao HS, Johnston LE, Chang DC, Bouvet M. A critical analysis of the American Joint Committee on Cancer (AJCC) staging system for differentiated thyroid carcinoma in young patients on the basis of the Surveillance, Epidemiology, and End Results (SEER) registry. Surgery. 2012 Aug; 152(2):145-51. PMID: 22503316; PMCID: PMC4416476.
    175. Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Saji S, Moriwaki H, Bouvet M, Hoffman RM. Imageable fluorescent metastasis resulting in transgenic GFP mice orthotopically implanted with human-patient primary pancreatic cancer specimens. Anticancer Res. 2012 Apr; 32(4):1175-80. PMID: 22493347.
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    176. Momiyama M, Kumamoto T, Suetsugu A, Kishimoto H, Chishima T, Tanaka K, Akiyama H, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. Major liver resection stimulates stromal recruitment and metastasis compared with repeated minor resection. J Surg Res. 2012 Nov; 178(1):280-7. PMID: 22487397; PMCID: PMC3396724.
    177. Ma W, Chen M, Kaushal S, McElroy M, Zhang Y, Ozkan C, Bouvet M, Kruse C, Grotjahn D, Ichim T, Minev B. PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses. Int J Nanomedicine. 2012; 7:1475-87. PMID: 22619507; PMCID: PMC3356185.
    178. Kimura H, Tome Y, Momiyama M, Hayashi K, Tsuchiya H, Bouvet M, Hoffman RM. Imaging the inhibition by anti-ß1 integrin antibody of lung seeding of single osteosarcoma cells in live mice. Int J Cancer. 2012 Nov 01; 131(9):2027-33. PMID: 22323248.
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    179. Chung AY, Tran TB, Brumund KT, Weisman RA, Bouvet M. Metastases to the thyroid: a review of the literature from the last decade. Thyroid. 2012 Mar; 22(3):258-68. PMID: 22313412.
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    180. Momiyama M, Zhao M, Kimura H, Tran B, Chishima T, Bouvet M, Endo I, Hoffman RM. Inhibition and eradication of human glioma with tumor-targeting Salmonella typhimurium in an orthotopic nude-mouse model. Cell Cycle. 2012 Feb 01; 11(3):628-32. PMID: 22274398; PMCID: PMC3315098.
    181. Yamauchi K, Tome Y, Yamamoto N, Hayashi K, Kimura H, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. Color-coded real-time subcellular fluorescence imaging of the interaction between cancer and host cells in live mice. Anticancer Res. 2012 Jan; 32(1):39-43. PMID: 22213286.
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    182. Hoffman RM, Bouvet M. Shedding (killer) light on tumors. Semin Thorac Cardiovasc Surg. 2012; 24(4):235-7. PMID: 23465668.
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    183. Bouvet M, Hoffman RM. In vivo imaging of pancreatic cancer with fluorescent proteins in mouse models. Methods Mol Biol. 2012; 872:51-67. PMID: 22700403.
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    184. Suetsugu A, Hassanein MK, Reynoso J, Osawa Y, Nagaki M, Moriwaki H, Saji S, Bouvet M, Hoffman RM. The cyan fluorescent protein nude mouse as a host for multicolor-coded imaging models of primary and metastatic tumor microenvironments. Anticancer Res. 2012 Jan; 32(1):31-8. PMID: 22213285.
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    185. Hassanein MK, Suetsugu A, Saji S, Moriwaki H, Bouvet M, Moossa AR, Hoffman RM. Stem-like and non-stem human pancreatic cancer cells distinguished by morphology and metastatic behavior. J Cell Biochem. 2011 Dec; 112(12):3549-54. PMID: 21780159.
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    186. Bouvet M, Hoffman RM. Glowing tumors make for better detection and resection. Sci Transl Med. 2011 Nov 23; 3(110):110fs10. PMID: 22116932.
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    187. Hayashi K, Kimura H, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Hasegawa A, Bouvet M, Hoffman RM. Comparison of cancer-cell seeding, viability and deformation in the lung, muscle and liver, visualized by subcellular real-time imaging in the live mouse. Anticancer Res. 2011 Nov; 31(11):3665-72. PMID: 22110185.
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    188. Menen RS, Pinney E, Kolostova K, Bobek V, Suetsugu A, Zhang N, Bouvet M, Hoffman RM. A rapid imageable in vivo metastasis assay for circulating tumor cells. Anticancer Res. 2011 Oct; 31(10):3125-8. PMID: 21965717.
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    189. Kishimoto H, Aki R, Urata Y, Bouvet M, Momiyama M, Tanaka N, Fujiwara T, Hoffman RM. Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection. Cell Cycle. 2011 Aug 15; 10(16):2737-41. PMID: 21785265; PMCID: PMC3219541.
    190. Tran Cao HS, McElroy M, Kaushal S, Hoffman RM, Bouvet M. Imaging of the interaction of cancer cells and the lymphatic system. Adv Drug Deliv Rev. 2011 Sep 10; 63(10-11):886-9. PMID: 21718727; PMCID: PMC3164753.
    191. Tran Cao HS, Kaushal S, Menen RS, Metildi CA, Lee C, Snyder CS, Talamini MA, Hoffman RM, Bouvet M. Submillimeter-resolution fluorescence laparoscopy of pancreatic cancer in a carcinomatosis mouse model visualizes metastases not seen with standard laparoscopy. J Laparoendosc Adv Surg Tech A. 2011 Jul-Aug; 21(6):485-9. PMID: 21699431; PMCID: PMC3142857.
    192. Grzesiak JJ, Tran Cao HS, Burton DW, Kaushal S, Vargas F, Clopton P, Snyder CS, Deftos LJ, Hoffman RM, Bouvet M. Knockdown of the ß(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis. Int J Cancer. 2011 Dec 15; 129(12):2905-15. PMID: 21491421; PMCID: PMC3167925.
    193. Suetsugu A, Osawa Y, Nagaki M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer. J Cell Biochem. 2011 Mar; 112(3):949-53. PMID: 21328469.
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    194. Suetsugu A, Osawa Y, Nagaki M, Moriwaki H, Saji S, Bouvet M, Hoffman RM. Simultaneous color-coded imaging to distinguish cancer "stem-like" and non-stem cells in the same tumor. J Cell Biochem. 2010 Nov 01; 111(4):1035-41. PMID: 20672309.
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    195. Tran Cao HS, Kaushal S, Snyder CS, Ongkeko WM, Hoffman RM, Bouvet M. Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer. Anticancer Res. 2010 Nov; 30(11):4415-22. PMID: 21115887; PMCID: PMC4453926.
    196. Erten A, Hall D, Hoh C, Tran Cao HS, Kaushal S, Esener S, Hoffman RM, Bouvet M, Chen J, Kesari S, Makale M. Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging. J Biomed Opt. 2010 Nov-Dec; 15(6):066012. PMID: 21198186; PMCID: PMC3014225.
    197. Gros SJ, Dohrmann T, Rawnaq T, Kurschat N, Bouvet M, Wessels J, Hoffmann RM, Izbicki JR, Kaifi JT. Orthotopic fluorescent peritoneal carcinomatosis model of esophageal cancer. Anticancer Res. 2010 Oct; 30(10):3933-8. PMID: 21036705.
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    198. Kimura H, Lee C, Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. UV light killing efficacy of fluorescent protein-expressing cancer cells in vitro and in vivo. J Cell Biochem. 2010 Aug 15; 110(6):1439-46. PMID: 20506255.
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    199. Grzesiak JJ, Vargas F, Bouvet M. Divalent cations modulate alpha2beta1 integrin-mediated malignancy in a novel 3-dimensional in vitro model of pancreatic cancer. Pancreas. 2010 Aug; 39(6):904-12. PMID: 20182393; PMCID: PMC2888635.
    200. Ganesan K, Achmad E, Sirlin CB, Bouvet M, Datnow B, Weidner N, Peterson MR. Amphicrine carcinoma of the liver. Ann Diagn Pathol. 2011 Oct; 15(5):355-7. PMID: 20952282.
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    201. Tran Cao HS, Bouvet M, Kaushal S, Keleman A, Romney E, Kim G, Fruehauf J, Imagawa DK, Hoffman RM, Katz MH. Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. Mol Cancer Ther. 2010 Jul; 9(7):2068-78. PMID: 20606044; PMCID: PMC4383085.
    202. Erten A, Wrasidlo W, Scadeng M, Esener S, Hoffman RM, Bouvet M, Makale M. Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model. Nanomedicine. 2010 Dec; 6(6):797-807. PMID: 20599526; PMCID: PMC2980586.
    203. Ma H, Li X, Yang Z, Okuno S, Kawaguchi T, Yagi S, Bouvet M, Hoffman RM. High antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugate. J Surg Res. 2011 Dec; 171(2):684-90. PMID: 20851421; PMCID: PMC3008337.
    204. Tran Cao HS, Kaushal S, Lee C, Snyder CS, Thompson KJ, Horgan S, Talamini MA, Hoffman RM, Bouvet M. Fluorescence laparoscopy imaging of pancreatic tumor progression in an orthotopic mouse model. Surg Endosc. 2011 Jan; 25(1):48-54. PMID: 20533064; PMCID: PMC3003784.
    205. Hu CM, Kaushal S, Tran Cao HS, Aryal S, Sartor M, Esener S, Bouvet M, Zhang L. Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells. Mol Pharm. 2010 Jun 07; 7(3):914-20. PMID: 20394436; PMCID: PMC2884057.
    206. Zhou J, Hu L, Yu Z, Zheng J, Yang D, Bouvet M, Hoffman RM. Marker expression in circulating cancer cells of pancreatic cancer patients. J Surg Res. 2011 Dec; 171(2):631-6. PMID: 20869080.
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    207. Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10920-5. PMID: 20534451; PMCID: PMC2890752.
    208. Brock MV, Bouvet M. Writing a successful NIH Mentored Career Development Grant (K award): hints for the junior faculty surgeon. Ann Surg. 2010 Jun; 251(6):1013-7. PMID: 20485135; PMCID: PMC4061563.
    209. Tran Cao HS, Kellogg B, Lowy AM, Bouvet M. Cystic neoplasms of the pancreas. Surg Oncol Clin N Am. 2010 Apr; 19(2):267-95. PMID: 20159515; PMCID: PMC4383087.
    210. Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA. Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4299-304. PMID: 20154271; PMCID: PMC2840076.
    211. Kimura H, Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Bouvet M, Hoffman RM. Real-time imaging of single cancer-cell dynamics of lung metastasis. J Cell Biochem. 2010 Jan 01; 109(1):58-64. PMID: 19911396.
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    212. Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2189-94. PMID: 20080647; PMCID: PMC2836678.
    213. Bouvet M, Hoffman RM. Clinically-relevent orthotopic metastatic models of pancreatic cancer imageable with fluorescent genetic reporters. Minerva Chir. 2009 Oct; 64(5):521-39. PMID: 19859041.
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    214. McElroy MK, Kaushal S, Tran Cao HS, Moossa AR, Talamini MA, Hoffman RM, Bouvet M. Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis. Mol Cancer Ther. 2009 Jul; 8(7):1779-86. PMID: 19584238; PMCID: PMC3487474.
    215. Nagakura C, Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice. Anticancer Res. 2009 Jun; 29(6):1873-8. PMID: 19528442.
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    216. Tran Cao HS, Reynoso J, Yang M, Kimura H, Kaushal S, Snyder CS, Hoffman RM, Bouvet M. Development of the transgenic cyan fluorescent protein (CFP)-expressing nude mouse for "Technicolor" cancer imaging. J Cell Biochem. 2009 May 15; 107(2):328-34. PMID: 19306297; PMCID: PMC2833326.
    217. Costantini CL, Reid TR, Bouvet M. Resection of hepatic metastasis after 5-fluorouracil and cofactor for colon cancer. Hepatogastroenterology. 2009 May-Jun; 56(91-92):645-9. PMID: 19621672.
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    218. Snyder CS, Kaushal S, Kono Y, Tran Cao HS, Hoffman RM, Bouvet M. Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer. BMC Cancer. 2009 Apr 08; 9:106. PMID: 19351417; PMCID: PMC2679761.
    219. Yam C, Zhao M, Hayashi K, Ma H, Kishimoto H, McElroy M, Bouvet M, Hoffman RM. Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. J Surg Res. 2010 Dec; 164(2):248-55. PMID: 19766244; PMCID: PMC2888721.
    220. Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Bouvet M, Hoffman RM. Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhimurium. Cell Cycle. 2009 Mar 15; 8(6):870-5. PMID: 19221501.
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    221. Tran Cao HS, Kimura H, Kaushal S, Snyder CS, Reynoso J, Hoffman RM, Bouvet M. The cyan fluorescent protein (CFP) transgenic mouse as a model for imaging pancreatic exocrine cells. JOP. 2009 Mar 09; 10(2):152-6. PMID: 19287108; PMCID: PMC4454444.
    222. Makale M, McElroy M, O'Brien P, Hoffman RM, Guo S, Bouvet M, Barnes L, Ingulli E, Cheresh D. Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue. J Biomed Opt. 2009 Mar-Apr; 14(2):024032. PMID: 19405761; PMCID: PMC3098575.
    223. Yang M, Reynoso J, Bouvet M, Hoffman RM. A transgenic red fluorescent protein-expressing nude mouse for color-coded imaging of the tumor microenvironment. J Cell Biochem. 2009 Feb 01; 106(2):279-84. PMID: 19097136; PMCID: PMC2739131.
    224. Zhou J, Yu Z, Zhao S, Hu L, Zheng J, Yang D, Bouvet M, Hoffman RM. Lentivirus-based DsRed-2-transfected pancreatic cancer cells for deep in vivo imaging of metastatic disease. J Surg Res. 2009 Nov; 157(1):63-70. PMID: 19589544.
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    225. McElroy M, Kaushal S, Bouvet M, Hoffman RM. Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment. Cell Cycle. 2008 Sep 15; 7(18):2916-21. PMID: 18787410; PMCID: PMC4383086.
    226. Grzesiak JJ, Bouvet M. Divalent cations modulate the integrin-mediated malignant phenotype in pancreatic cancer cells. Cancer Sci. 2008 Aug; 99(8):1553-63. PMID: 18754866.
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    227. Kaushal S, McElroy MK, Luiken GA, Talamini MA, Moossa AR, Hoffman RM, Bouvet M. Fluorophore-conjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer. J Gastrointest Surg. 2008 Nov; 12(11):1938-50. PMID: 18665430; PMCID: PMC4396596.
    228. McElroy M, Kaushal S, Luiken GA, Talamini MA, Moossa AR, Hoffman RM, Bouvet M. Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation. World J Surg. 2008 Jun; 32(6):1057-66. PMID: 18264829; PMCID: PMC4378829.
    229. Chae AW, Perricone A, Brumund KT, Bouvet M. Outpatient video-assisted thoracoscopic surgery (VATS) for ectopic mediastinal parathyroid adenoma: a case report and review of the literature. J Laparoendosc Adv Surg Tech A. 2008 Jun; 18(3):383-90. PMID: 18503371.
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    230. Grzesiak JJ, Bouvet M. Activation of the alpha2beta1 integrin-mediated malignant phenotype on type I collagen in pancreatic cancer cells by shifts in the concentrations of extracellular Mg2+ and Ca2+. Int J Cancer. 2008 May 15; 122(10):2199-209. PMID: 18224679.
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    231. McElroy M, Hayashi K, Garmy-Susini B, Kaushal S, Varner JA, Moossa AR, Hoffman RM, Bouvet M. Fluorescent LYVE-1 antibody to image dynamically lymphatic trafficking of cancer cells in vivo. J Surg Res. 2009 Jan; 151(1):68-73. PMID: 18599080; PMCID: PMC2628480.
    232. Yamauchi K, Yang M, Hayashi K, Jiang P, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Induction of cancer metastasis by cyclophosphamide pretreatment of host mice: an opposite effect of chemotherapy. Cancer Res. 2008 Jan 15; 68(2):516-20. PMID: 18199547.
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    233. McElroy M, Bouvet M, Hoffman RM. Chapter 2. Color-coded fluorescent mouse models of cancer cell interactions with blood vessels and lymphatics. Methods Enzymol. 2008; 445:27-52. PMID: 19022054.
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    234. Grzesiak JJ, Ho JC, Moossa AR, Bouvet M. The integrin-extracellular matrix axis in pancreatic cancer. Pancreas. 2007 Nov; 35(4):293-301. PMID: 18090233.
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    235. Hayashi K, Jiang P, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Real-time imaging of tumor-cell shedding and trafficking in lymphatic channels. Cancer Res. 2007 Sep 01; 67(17):8223-8. PMID: 17804736.
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    236. Yamauchi K, Yang M, Hayashi K, Jiang P, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Imaging of nucleolar dynamics during the cell cycle of cancer cells in live mice. Cell Cycle. 2007 Nov 01; 6(21):2706-8. PMID: 17912040.
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    237. Lee JK, Obrzut SL, Yi ES, Deftos LJ, Bouvet M. Incidental finding of metastatic papillary thyroid carcinoma in a patient with primary hyperparathyroidism. Endocr Pract. 2007 Jul-Aug; 13(4):380-3. PMID: 17669714.
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    238. Grzesiak JJ, Smith KC, Burton DW, Deftos LJ, Bouvet M. Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells. Surgery. 2007 Jun; 141(6):804-14. PMID: 17560257; PMCID: PMC1994963.
    239. Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Amoh Y, Hoffman RM, Bouvet M. Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. J Surg Res. 2007 Jun 15; 140(2):165-70. PMID: 17418866; PMCID: PMC1994962.
    240. Ji Y, Hayashi K, Amoh Y, Tsuji K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. Anticancer Res. 2007 Mar-Apr; 27(2):713-8. PMID: 17465193.
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    241. Amoh Y, Li L, Katsuoka K, Bouvet M, Hoffman RM. GFP-expressing vascularization of Gelfoam as a rapid in vivo assay of angiogenesis stimulators and inhibitors. Biotechniques. 2007 Mar; 42(3):294, 296, 298. PMID: 17390535.
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    242. Grzesiak JJ, Bouvet M. Determination of the ligand-binding specificities of the alpha2beta1 and alpha1beta1 integrins in a novel 3-dimensional in vitro model of pancreatic cancer. Pancreas. 2007 Mar; 34(2):220-8. PMID: 17312461.
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    243. Bouvet M, Tsuji K, Yang M, Jiang P, Moossa AR, Hoffman RM. In vivo color-coded imaging of the interaction of colon cancer cells and splenocytes in the formation of liver metastases. Cancer Res. 2006 Dec 01; 66(23):11293-7. PMID: 17145875.
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    244. Amoh Y, Bouvet M, Li L, Tsuji K, Moossa AR, Katsuoka K, Hoffman RM. Visualization of nascent tumor angiogenesis in lung and liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP mice. Clin Exp Metastasis. 2006; 23(7-8):315-22. PMID: 17136576.
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    245. Amoh Y, Nagakura C, Maitra A, Moossa AR, Katsuoka K, Hoffman RM, Bouvet M. Dual-color imaging of nascent angiogenesis and its inhibition in liver metastases of pancreatic cancer. Anticancer Res. 2006 Sep-Oct; 26(5A):3237-42. PMID: 17094435.
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    246. Newman EM, Bouvet M, Borgehi S, Herold DA, Deftos LJ. Causes of hypercalcemia in a population of military veterans in the United States. Endocr Pract. 2006 Sep-Oct; 12(5):535-41. PMID: 17002928.
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    247. Jiang P, Yamauchi K, Yang M, Tsuji K, Xu M, Maitra A, Bouvet M, Hoffman RM. Tumor cells genetically labeled with GFP in the nucleus and RFP in the cytoplasm for imaging cellular dynamics. Cell Cycle. 2006 Jun; 5(11):1198-201. PMID: 16760659.
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    248. Yamauchi K, Yang M, Jiang P, Xu M, Yamamoto N, Tsuchiya H, Tomita K, Moossa AR, Bouvet M, Hoffman RM. Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. Cancer Res. 2006 Apr 15; 66(8):4208-14. PMID: 16618743.
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    249. Tsuji K, Yang M, Jiang P, Maitra A, Kaushal S, Yamauchi K, Katz MH, Moossa AR, Hoffman RM, Bouvet M. Common bile duct injection as a novel method for establishing red fluorescent protein (RFP)-expressing human pancreatic cancer in nude mice. JOP. 2006 Mar 09; 7(2):193-9. PMID: 16525203.
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    250. Grzesiak JJ, Burton DW, Deftos LJ, Bouvet M. Identification of DU 145 prostate cancer cell proteins that bind to the carboxy-terminal peptide of human PTHrP in vitro. Peptides. 2006 Jul; 27(7):1898-901. PMID: 16513210.
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    251. Amoh Y, Li L, Tsuji K, Moossa AR, Katsuoka K, Hoffman RM, Bouvet M. Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine. J Surg Res. 2006 May 15; 132(2):164-9. PMID: 16500746.
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    252. Tsuji K, Yamauchi K, Yang M, Jiang P, Bouvet M, Endo H, Kanai Y, Yamashita K, Moossa AR, Hoffman RM. Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area. Cancer Res. 2006 Jan 01; 66(1):303-6. PMID: 16397243.
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    253. Bouvet M, Spernyak J, Katz MH, Mazurchuk RV, Takimoto S, Bernacki R, Rustum YM, Moossa AR, Hoffman RM. High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer. Cancer Res. 2005 Nov 01; 65(21):9829-33. PMID: 16267005.
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    254. Katz MH, Savides TJ, Moossa AR, Bouvet M. An evidence-based approach to the diagnosis and staging of pancreatic cancer. Pancreatology. 2005; 5(6):576-90. PMID: 16110256.
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    255. Amoh Y, Yang M, Li L, Reynoso J, Bouvet M, Moossa AR, Katsuoka K, Hoffman RM. Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis. Cancer Res. 2005 Jun 15; 65(12):5352-7. PMID: 15958583.
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    256. Tsuboi K, Grzesiak JJ, Bouvet M, Hashimoto M, Masliah E, Shults CW. Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death. Mol Cell Neurosci. 2005 Jun; 29(2):259-68. PMID: 15911350.
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    257. Yamauchi K, Yang M, Jiang P, Yamamoto N, Xu M, Amoh Y, Tsuji K, Bouvet M, Tsuchiya H, Tomita K, Moossa AR, Hoffman RM. Real-time in vivo dual-color imaging of intracapillary cancer cell and nucleus deformation and migration. Cancer Res. 2005 May 15; 65(10):4246-52. PMID: 15899816.
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    258. Grzesiak JJ, Smith KC, Chalberg C, Truong C, Burton DW, Deftos LJ, Bouvet M. Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. Endocrinology. 2005 Aug; 146(8):3567-76. PMID: 15878959.
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    259. Grzesiak JJ, Smith KC, Burton DW, Deftos LJ, Bouvet M. GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells. Int J Cancer. 2005 Apr 20; 114(4):522-30. PMID: 15609321.
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    260. Grzesiak JJ, Smith KC, Chalberg C, Burton DW, Deftos LJ, Bouvet M. Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells. Int J Gastrointest Cancer. 2005; 36(3):131-46. PMID: 16720909.
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    261. Grzesiak JJ, Clopton P, Chalberg C, Smith K, Burton DW, Silletti S, Moossa AR, Deftos LJ, Bouvet M. The extracellular matrix differentially regulates the expression of PTHrP and the PTH/PTHrP receptor in FG pancreatic cancer cells. Pancreas. 2004 Aug; 29(2):85-92. PMID: 15257098.
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    262. Bouvet M. Tumor markers for pancreatic cancer: what happens when preoperative CA 19-9 is undetectable? Ann Surg Oncol. 2004 Jul; 11(7):637-8. PMID: 15197009.
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    263. Katz MH, Bouvet M, Al-Refaie W, Gilpin EA, Moossa AR. Non-pancreatic periampullary adenocarcinomas: an explanation for favorable prognosis. Hepatogastroenterology. 2004 May-Jun; 51(57):842-6. PMID: 15143931.
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    264. Alrefaie W, Katz MH, Easter DW, Yi ES, Weidner N, Savides TJ, Moossa AR, Bouvet M. Simultaneous serous cystadenoma of the pancreas and mucinous cystadenoma of the appendix. JOP. 2004 Mar; 5(2):97-100. PMID: 15007191.
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    265. Takabe K, Holman PR, Herbst KD, Glass CA, Bouvet M. Successful perioperative management of factor X deficiency associated with primary amyloidosis. J Gastrointest Surg. 2004 Mar-Apr; 8(3):358-62. PMID: 15019934.
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    266. Katz MH, Bouvet M, Takimoto S, Spivack D, Moossa AR, Hoffman RM. Survival efficacy of adjuvant cytosine-analogue CS-682 in a fluorescent orthotopic model of human pancreatic cancer. Cancer Res. 2004 Mar 01; 64(5):1828-33. PMID: 14996746.
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    267. Katz MH, Takimoto S, Spivack D, Moossa AR, Hoffman RM, Bouvet M. An imageable highly metastatic orthotopic red fluorescent protein model of pancreatic cancer. Clin Exp Metastasis. 2004; 21(1):7-12. PMID: 15065597.
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    268. Zhou W, Katz MH, Deftos LJ, Snyder CS, Baird S, Bouvet M. Metachronous double parathyroid adenomas involving two different cell types: chief cell and oxyphil cell. Endocr Pract. 2003 Nov-Dec; 9(6):522-5. PMID: 14715480.
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    269. Katz MH, Bouvet M, Takimoto S, Spivack D, Moossa AR, Hoffman RM. Selective antimetastatic activity of cytosine analog CS-682 in a red fluorescent protein orthotopic model of pancreatic cancer. Cancer Res. 2003 Sep 01; 63(17):5521-5. PMID: 14500389.
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    270. Katz MH, Spivack DE, Takimoto S, Fang B, Burton DW, Moossa AR, Hoffman RM, Bouvet M. Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter. Ann Surg Oncol. 2003 Aug; 10(7):762-72. PMID: 12900367.
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    271. Katz MH, Takimoto S, Spivack D, Moossa AR, Hoffman RM, Bouvet M. A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. J Surg Res. 2003 Jul; 113(1):151-60. PMID: 12943825.
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    272. Overstreet K, Wixom C, Shabaik A, Bouvet M, Herndier B. Adenomatoid tumor of the pancreas: a case report with comparison of histology and aspiration cytology. Mod Pathol. 2003 Jun; 16(6):613-7. PMID: 12808068.
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    273. Katz MH, Bouvet M. Novel gene therapy approaches to pancreatic cancer. Int J Gastrointest Cancer. 2003; 33(1):89-97. PMID: 12909741.
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    274. Sun FX, Tohgo A, Bouvet M, Yagi S, Nassirpour R, Moossa AR, Hoffman RM. Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model. Cancer Res. 2003 Jan 01; 63(1):80-5. PMID: 12517781.
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    275. Du E, Overstreet K, Zhou W, Baird G, Baird S, Bouvet M, Haghighi P. Fine needle aspiration of splenic extramedullary hematopoiesis presenting as a solitary mass. A case report. Acta Cytol. 2002 Nov-Dec; 46(6):1138-42. PMID: 12462096.
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    276. Parhizkar N, Jones VE, McClay EF, Yi ES, Bouvet M. Metastatic melanoma in a patient with Clouston syndrome successfully treated with isolated hyperthermic limb perfusion. J Cutan Med Surg. 2003 Jan-Feb; 7(1):43-6. PMID: 12362262.
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    277. Pirocanac EC, Nassirpour R, Yang M, Wang J, Nardin SR, Gu J, Fang B, Moossa AR, Hoffman RM, Bouvet M. Bax-induction gene therapy of pancreatic cancer. J Surg Res. 2002 Aug; 106(2):346-51. PMID: 12175991.
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    278. Shen J, Wallace AM, Bouvet M. The role of sentinel lymph node biopsy for melanoma. Semin Oncol. 2002 Aug; 29(4):341-52. PMID: 12170437.
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    279. Bouvet M, Nardin SR, Burton DW, Lee NC, Yang M, Wang X, Baranov E, Behling C, Moossa AR, Hoffman RM, Deftos LJ. Parathyroid hormone-related protein as a novel tumor marker in pancreatic adenocarcinoma. Pancreas. 2002 Apr; 24(3):284-90. PMID: 11893937.
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    280. Yang M, Baranov E, Wang JW, Jiang P, Wang X, Sun FX, Bouvet M, Moossa AR, Penman S, Hoffman RM. Direct external imaging of nascent cancer, tumor progression, angiogenesis, and metastasis on internal organs in the fluorescent orthotopic model. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3824-9. PMID: 11891294; PMCID: PMC122608.
    281. Bouvet M, Wang J, Nardin SR, Nassirpour R, Yang M, Baranov E, Jiang P, Moossa AR, Hoffman RM. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res. 2002 Mar 01; 62(5):1534-40. PMID: 11888932.
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    282. Bouvet M, Nardin SR, Burton DW, Behling C, Carethers JM, Moossa AR, Deftos LJ. Human pancreatic adenocarcinomas express parathyroid hormone-related protein. J Clin Endocrinol Metab. 2001 Jan; 86(1):310-6. PMID: 11232017.
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