Howard Feldman

Title(s)Professor, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-9258-4538 Additional info
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    Collapse Biography 
    Collapse Education and Training
    McGill University, Quebec, CanadaMDCM06/1978Medicine
    Collapse Awards and Honors
    University of British Columbia1997Martin M Hoffman Award for Excellence in Research
    Thomson Reuters2002  - 2012Most Highly Cited Researchers in Neuroscience & Behavior; World's Most Influential Scientific Mind
    Web of Science Clarivate Analytics2007  - 2018Top 1% Most Cited Researcher in Neuroscience
    University of British Columbia2008Distinguished Achievement Award for Outstanding Contribution by a Senior Faculty Member
    Canadian Consortium of Clinical Cognitive Centres for Research (C5R)2013Irma M Parhad Award for Excellence
    Thomson Reuters2014  - 2015Most Highly Cited Researchers in Neuroscience & Behavior; World's Most Influential Scientific Mind
    Blue Ridge Institute for Medical Research2019#1 ranking PI in Neurosciences funding from the NIH

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Asian Cohort for Alzheimer's Disease (ACAD)
    NIH U19AG079774Jul 1, 2023 - Jun 30, 2028
    Role: Co-Investigator
    Phase II randomized controlled trial of benfotiamine in early Alzheimer's Disease
    NIH R01AG076634Jul 15, 2022 - Jun 30, 2027
    Role: Principal Investigator
    A Single Ascending Dose / Multiple Ascending Dose Phase I study of the GSM 776890 in healthy normal subjects
    NIH R01AG070353Feb 1, 2021 - Nov 30, 2023
    Role: Coordinating Center Principal Investigator
    UCSD Alzheimer's Disease Research Centers P30
    NIH P30AG062429May 1, 2019 - Mar 31, 2024
    Role: Co-Investigator
    Canadian Consortium on Neurodegeneration and Aging (CCNA)
    Canadian Institutes of Health Research (CIHR) 137794Apr 1, 2019 - Mar 31, 2024
    Role: Co-Principal Investigator
    Description: This grant funds a national network investigating prevention, quality of life, and treatment. It includes the COMPASS-ND, and the CAN THUMBS UP program
    A Seamless Phase 2A-B Randomized Double Blind Placebo Controlled Trial to Evaluate the Efficacy and Safety of PQ 912 in Patients with Early Alzheimer's Disease
    NIH R01AG061146Apr 1, 2019 - Jun 30, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Developing the Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia program. Alzheimers Dement (N Y). 2024 Jan-Mar; 10(1):e12457. Moukarzel S, Zlatar ZZ, Hartman SJ, Lomas D, Feldman HH, Banks SJ, HALT-AD Study Group. PMID: 38440783; PMCID: PMC10909928.
      View in: PubMed   Mentions: 1  
    2. Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians. Alzheimers Dement. 2024 03; 20(3):2058-2071. Ho PC, Yu WH, Tee BL, Lee WP, Li C, Gu Y, Yokoyama JS, Reyes-Dumeyer D, Choi YB, Yang HS, Vardarajan BN, Tzuang M, Lieu K, Lu A, Faber KM, Potter ZD, Revta C, Kirsch M, McCallum J, Mei D, Booth B, Cantwell LB, Chen F, Chou S, Clark D, Deng M, Hong TH, Hwang LJ, Jiang L, Joo Y, Kang Y, Kim ES, Kim H, Kim K, Kuzma AB, Lam E, Lanata SC, Lee K, Li D, Li M, Li X, Liu CL, Liu C, Liu L, Lupo JL, Nguyen K, Pfleuger SE, Qian J, Qian W, Ramirez V, Russ KA, Seo EH, Song YE, Tartaglia MC, Tian L, Torres M, Vo N, Wong EC, Xie Y, Yau EB, Yi I, Yu V, Zeng X, St George-Hyslop P, Au R, Schellenberg GD, Dage JL, Varma R, Hsiung GR, Rosen H, Henderson VW, Foroud T, Kukull WA, Peavy GM, Lee H, Feldman HH, Mayeux R, Chui H, Jun GR, Ta Park VM, Chow TW, Wang LS. PMID: 38215053; PMCID: PMC10984480.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    3. Efficacy assessment of an active tau immunotherapy in Alzheimer's disease patients with amyloid and tau pathology: a post hoc analysis of the "ADAMANT" randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trial. EBioMedicine. 2024 Jan; 99:104923. Cullen NC, Novak P, Tosun D, Kovacech B, Hanes J, Kontsekova E, Fresser M, Ropele S, Feldman HH, Schmidt R, Winblad B, Zilka N. PMID: 38101301; PMCID: PMC10733085.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    4. Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease. Front Pharmacol. 2023; 14:1190402. Boyarko B, Podvin S, Greenberg B, Momper JD, Huang Y, Gerwick WH, Bang AG, Quinti L, Griciuc A, Kim DY, Tanzi RE, Feldman HH, Hook V. PMID: 37601062; PMCID: PMC10436590.
      View in: PubMed   Mentions: 3  
    5. Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-Month Intervention Study. J Prev Alzheimers Dis. 2023; 10(4):875-885. Feldman HH, Belleville S, Nygaard HB, Montero-Odasso M, Durant J, Lupo JL, Revta C, Chan S, Cuesta M, Slack PJ, Winer S, Brewster PWH, Hofer SM, Lim A, Centen A, Jacobs DM, Anderson ND, Walker JD, Speechley MR, Zou GY, Chertkow H. PMID: 37874110; PMCID: PMC10258470.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias. Alzheimers Dement. 2023 03; 19(3):1041-1066. Yassine HN, Self W, Kerman BE, Santoni G, Navalpur Shanmugam N, Abdullah L, Golden LR, Fonteh AN, Harrington MG, Gräff J, Gibson GE, Kalaria R, Luchsinger JA, Feldman HH, Swerdlow RH, Johnson LA, Albensi BC, Zlokovic BV, Tanzi R, Cunnane S, Samieri C, Scarmeas N, Bowman GL. PMID: 36479795; PMCID: PMC10576546.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    7. RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia-an international Delphi consensus. Alzheimers Res Ther. 2022 11 11; 14(1):169. O'Brien JT, Chouliaras L, Sultana J, Taylor JP, Ballard C, RENEWAL Study Group. PMID: 36369100; PMCID: PMC9650797.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Pharmacological thiamine levels as a therapeutic approach in Alzheimer's disease. Front Med (Lausanne). 2022; 9:1033272. Gibson GE, Feldman HH, Zhang S, Flowers SA, Luchsinger JA. PMID: 36275801; PMCID: PMC9585656.
      View in: PubMed   Mentions: 8  
    9. Exploring Social Cognition Tests to Differentiate Frontotemporal Dementia from Depression: A Two-Step Pilot Study. Alzheimer Dis Assoc Disord. 2023 Apr-Jun 01; 37(2):145-148. Lichtenstein ML, Stewart PV, Kirchner HL, Finney G, Feldman HH. PMID: 36030814; PMCID: PMC10219668.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Home EEG sleep assessment shows reduced slow-wave sleep in mild-moderate Alzheimer's disease. Alzheimers Dement (N Y). 2022; 8(1):e12347. Kent BA, Casciola AA, Carlucci SK, Chen M, Stager S, Mirian MS, Slack P, Valerio J, McKeown MJ, Feldman HH, Nygaard HB. PMID: 35992215; PMCID: PMC9381912.
      View in: PubMed   Mentions: 2  
    11. Multidomain trials to prevent dementia: addressing methodological challenges. Alzheimers Res Ther. 2022 07 11; 14(1):94. Montero-Odasso M, Zou GY, Kamkar N, Feldman HH, Belleville S, Chertkow H, Nygaard HB, Son S, Speechley M. PMID: 35820915; PMCID: PMC9275261.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial. JAMA Neurol. 2022 06 01; 79(6):565-574. Rafii MS, Sol O, Mobley WC, Delpretti S, Skotko BG, Burke AD, Sabbagh MN, Yuan SH, Rissman RA, Pulsifer M, Evans C, Evans AC, Beth G, Fournier N, Gray JA, Dos Santos AM, Hliva V, Vukicevic M, Kosco-Vilbois M, Streffer J, Pfeifer A, Feldman HH. PMID: 35532913; PMCID: PMC9086937.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    13. T2 Protect AD: Achieving a rapid recruitment timeline in a multisite clinical trial for individuals with mild to moderate Alzheimer's disease. Alzheimers Dement (N Y). 2022; 8(1):e12265. Shadyab AH, LaCroix AZ, Matthews G, Bennett D, Shadyab AA, Tan D, Thomas RG, Mason J, Lopez A, Askew B, Donahue L, Kaplita S, Qureshi IA, Huisa B, Feldman HH, Alzheimer's Disease Cooperative Study T2 Protect AD Study Group. PMID: 35310528; PMCID: PMC8919121.
      View in: PubMed   Mentions: 2  
    14. Impact of potential modifications to Alzheimer's disease clinical trials in response to disruption by COVID-19: a simulation study. Alzheimers Res Ther. 2021 12 20; 13(1):201. Schneider LS, Qiu Y, Thomas RG, Evans C, Jacobs DM, Jin S, Kaye JA, LaCroix AZ, Messer K, Salmon DP, Sano M, Schafer K, Feldman HH. PMID: 34930444; PMCID: PMC8686345.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    15. Consensus Statement Regarding the Application of Biogen to Health Canada for Approval of Aducanumab. Can Geriatr J. 2021 Dec; 24(4):373-378. Chertkow H, Rockwood K, Hogan DB, Phillips N, Montero-Odasso M, Amanullah S, Black S, Bocti C, Borrie M, Feldman H, Freedman M, Hsiung R, Kirk A, Masellis M, Nygaard H, Rajji T, Verret L. PMID: 34912492; PMCID: PMC8629494.
      View in: PubMed   Mentions: 5  
    16. Committee on High-quality Alzheimer's Disease Studies (CHADS) consensus report. Alzheimers Dement. 2022 06; 18(6):1109-1118. Jicha GA, Abner EL, Arnold SE, Carrillo MC, Dodge HH, Edland SD, Fargo KN, Feldman HH, Goldstein LB, Hendrix J, Peters R, Robillard JM, Schneider LS, Titiner JR, Weber CJ, Clinical Trial Advancement & Methodology Professional Interest Area of the International Society to . PMID: 34590417; PMCID: PMC8960469.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Current directions in tau research: Highlights from Tau 2020. Alzheimers Dement. 2022 05; 18(5):988-1007. Sexton C, Snyder H, Beher D, Boxer AL, Brannelly P, Brion JP, Buée L, Cacace AM, Chételat G, Citron M, DeVos SL, Diaz K, Feldman HH, Frost B, Goate AM, Gold M, Hyman B, Johnson K, Karch CM, Kerwin DR, Koroshetz WJ, Litvan I, Morris HR, Mummery CJ, Mutamba J, Patterson MC, Quiroz YT, Rabinovici GD, Rommel A, Shulman MB, Toledo-Sherman LM, Weninger S, Wildsmith KR, Worley SL, Carrillo MC. PMID: 34581500.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    18. Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial. Alzheimers Dement. 2021 11; 17(11):1808-1817. Shadyab AH, LaCroix AZ, Feldman HH, van Dyck CH, Okonkwo OC, Tam SP, Fairchild JK, Welsh-Bohmer KA, Matthews G, Bennett D, Shadyab AA, Schafer KA, Morrison RH, Kipperman SA, Mason J, Tan D, Thomas RG, Cotman CW, Baker LD, ADCS EXERT Study Group. PMID: 34297895; PMCID: PMC9292825.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group. Lancet Neurol. 2021 06; 20(6):484-496. Dubois B, Villain N, Frisoni GB, Rabinovici GD, Sabbagh M, Cappa S, Bejanin A, Bombois S, Epelbaum S, Teichmann M, Habert MO, Nordberg A, Blennow K, Galasko D, Stern Y, Rowe CC, Salloway S, Schneider LS, Cummings JL, Feldman HH. PMID: 33933186; PMCID: PMC8339877.
      View in: PubMed   Mentions: 262     Fields:    Translation:Humans
    20. Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study. J Clin Med. 2021 Apr 28; 10(9). Hendrix JA, Airey DC, Britton A, Burke AD, Capone GT, Chavez R, Chen J, Chicoine B, Costa ACS, Dage JL, Doran E, Esbensen A, Evans CL, Faber KM, Foroud TM, Hart S, Haugen K, Head E, Hendrix S, Hillerstrom H, Kishnani PS, Krell K, Ledesma DL, Lai F, Lott I, Ochoa-Lubinoff C, Mason J, Nicodemus-Johnson J, Proctor NK, Pulsifer MB, Revta C, Rosas HD, Rosser TC, Santoro S, Schafer K, Scheidemantel T, Schmitt F, Skotko BG, Stasko MR, Talboy A, Torres A, Wilmes K, Woodward J, Zimmer JA, Feldman HH, Mobley W. PMID: 33924960; PMCID: PMC8124643.
      View in: PubMed   Mentions: 12  
    21. Value-Generating Exploratory Trials in Neurodegenerative Dementias. Neurology. 2021 05 18; 96(20):944-954. Friedman LG, McKeehan N, Hara Y, Cummings JL, Matthews DC, Zhu J, Mohs RC, Wang D, Hendrix SB, Quintana M, Schneider LS, Grundman M, Dickson SP, Feldman HH, Jaeger J, Finger EC, Ryan JM, Niehoff D, Dickinson SL, Markowitz JT, Owen M, Travaglia A, Fillit HM. PMID: 33674360; PMCID: PMC8205472.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Rasagiline effects on glucose metabolism, cognition, and tau in Alzheimer's dementia. Alzheimers Dement (N Y). 2021; 7(1):e12106. Matthews DC, Ritter A, Thomas RG, Andrews RD, Lukic AS, Revta C, Kinney JW, Tousi B, Leverenz JB, Fillit H, Zhong K, Feldman HH, Cummings J. PMID: 33614888; PMCID: PMC7882538.
      View in: PubMed   Mentions: 19  
    23. Brain volumetric deficits in MAPT mutation carriers: a multisite study. Ann Clin Transl Neurol. 2021 01; 8(1):95-110. Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, Grossman M, Coppola G, Dickerson BC, Bordelon YM, Faber K, Feldman HH, Fields JA, Fong JC, Foroud T, Gavrilova RH, Ghoshal N, Graff-Radford NR, Hsiung GR, Huey ED, Irwin DJ, Kantarci K, Kaufer DI, Karydas AM, Knopman DS, Kornak J, Kramer JH, Kukull WA, Lapid MI, Litvan I, Mackenzie IRA, Mendez MF, Miller BL, Onyike CU, Pantelyat AY, Rademakers R, Marisa Ramos E, Roberson ED, Carmela Tartaglia M, Tatton NA, Toga AW, Vetor A, Weintraub S, Wong B, Wszolek ZK, ARTFL/LEFFTDS Consortium, Van Swieten JC, Lee SE. PMID: 33247623; PMCID: PMC7818091.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    24. Enriching the design of Alzheimer's disease clinical trials: Application of the polygenic hazard score and composite outcome measures. Alzheimers Dement (N Y). 2020; 6(1):e12071. Banks SJ, Qiu Y, Fan CC, Dale AM, Zou J, Askew B, Feldman HH, Alzheimer's Disease Neuroimaging Initiative. PMID: 32999917; PMCID: PMC7507583.
      View in: PubMed   Mentions: 8  
    25. Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS-Cog-Exec. Alzheimers Dement (N Y). 2020; 6(1):e12059. Jacobs DM, Thomas RG, Salmon DP, Jin S, Feldman HH, Cotman CW, Baker LD, Alzheimer's Disease Cooperative Study EXERT Study Group, Alzheimer's Disease Neuroimaging Initiative. PMID: 32995469; PMCID: PMC7507362.
      View in: PubMed   Mentions: 8  
    26. Association of anticholinergic medications and AD biomarkers with incidence of MCI among cognitively normal older adults. Neurology. 2020 10 20; 95(16):e2295-e2304. Weigand AJ, Bondi MW, Thomas KR, Campbell NL, Galasko DR, Salmon DP, Sewell D, Brewer JB, Feldman HH, Delano-Wood L, Alzheimer's Disease Neuroimaging Initiative. PMID: 32878992; PMCID: PMC7713781.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    27. Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer's disease. Prog Neurobiol. 2021 02; 197:101902. Kent BA, Feldman HH, Nygaard HB. PMID: 32877742; PMCID: PMC7855222.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    28. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimers Dement. 2020 07; 16(7):1078-1094. Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, Choi SH, Chowdhary N, Crivelli L, Torre R, Du Y, Dua T, Espeland M, Feldman HH, Hartmanis M, Hartmann T, Heffernan M, Henry CJ, Hong CH, Håkansson K, Iwatsubo T, Jeong JH, Jimenez-Maggiora G, Koo EH, Launer LJ, Lehtisalo J, Lopera F, Martínez-Lage P, Martins R, Middleton L, Molinuevo JL, Montero-Odasso M, Moon SY, Morales-Pérez K, Nitrini R, Nygaard HB, Park YK, Peltonen M, Qiu C, Quiroz YT, Raman R, Rao N, Ravindranath V, Rosenberg A, Sakurai T, Salinas RM, Scheltens P, Sevlever G, Soininen H, Sosa AL, Suemoto CK, Tainta-Cuezva M, Velilla L, Wang Y, Whitmer R, Whitmer R, Xu X, Bain LJ, Solomon A, Ngandu T, Carrillo MC. PMID: 32627328; PMCID: PMC9527644.
      View in: PubMed   Mentions: 184     Fields:    Translation:Humans
    29. Expanding the Phenotype of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FUS). J Neuropathol Exp Neurol. 2020 07 01; 79(7):809-812. Chornenka K, Hirsch-Reinshagen V, Perez-Rosendahl M, Feldman H, Segal-Gidan F, Vinters HV, Mackenzie IR. PMID: 32483606.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 03 16; 15(1):21. Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, Roberge M, Nygaard HB. PMID: 32178712; PMCID: PMC7075020.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    31. New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. Alzheimers Dement. 2020 01; 16(1):131-143. Boxer AL, Gold M, Feldman H, Boeve BF, Dickinson SL, Fillit H, Ho C, Paul R, Pearlman R, Sutherland M, Verma A, Arneric SP, Alexander BM, Dickerson BC, Dorsey ER, Grossman M, Huey ED, Irizarry MC, Marks WJ, Masellis M, McFarland F, Niehoff D, Onyike CU, Paganoni S, Panzara MA, Rockwood K, Rohrer JD, Rosen H, Schuck RN, Soares HD, Tatton N. PMID: 31668596; PMCID: PMC6949386.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    32. Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation. Stem Cell Res. 2019 12; 41:101582. Frew J, Wu X, Hsiung GY, Feldman HH, Mackenzie IR, Nygaard HB. PMID: 31707213.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. The "rights" of precision drug development for Alzheimer's disease. Alzheimers Res Ther. 2019 08 31; 11(1):76. Cummings J, Feldman HH, Scheltens P. PMID: 31470905; PMCID: PMC6717388.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    34. A randomized clinical trial to evaluate home-based assessment of people over 75 years old. Alzheimers Dement. 2019 05; 15(5):615-624. Sano M, Zhu CW, Kaye J, Mundt JC, Hayes TL, Ferris S, Thomas RG, Sun CK, Jiang Y, Donohue MC, Schneider LS, Egelko S, Aisen PS, Feldman HH, Alzheimer Disease Cooperative Study Investigators. PMID: 30872114.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Delayed daily activity and reduced NREM slow-wave power in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Neurobiol Aging. 2019 06; 78:74-86. Kent BA, Michalik M, Marchant EG, Yau KW, Feldman HH, Mistlberger RE, Nygaard HB. PMID: 30884411.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    36. Adaptive crossover designs for assessment of symptomatic treatments targeting behaviour in neurodegenerative disease: a phase 2 clinical trial of intranasal oxytocin for frontotemporal dementia (FOXY). Alzheimers Res Ther. 2018 09 27; 10(1):102. Finger E, Berry S, Cummings J, Coleman K, Hsiung R, Feldman HH, Boxer A. PMID: 30261917; PMCID: PMC6161323.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    37. 16-Year Survival of the Canadian Collaborative Cohort of Related Dementias. Can J Neurol Sci. 2018 07; 45(4):367-374. Lichtenstein ML, Fallah N, Mudge B, Hsiung GR, Foti D, Beattie BL, Feldman HH. PMID: 29730995.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. Gray matter changes in asymptomatic C9orf72 and GRN mutation carriers. Neuroimage Clin. 2018; 18:591-598. Popuri K, Dowds E, Beg MF, Balachandar R, Bhalla M, Jacova C, Buller A, Slack P, Sengdy P, Rademakers R, Wittenberg D, Feldman HH, Mackenzie IR, Hsiung GR. PMID: 29845007; PMCID: PMC5964622.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    39. Neurobehavioral characterization of adult-onset Alexander disease: A family study. Neurol Clin Pract. 2017 Oct; 7(5):425-429. Lichtenstein ML, Dwosh E, Roy Chowdhury A, Farrer MJ, McKenzie MB, Guella I, Evans DM, Nygaard HB, Shewchuk JR, Hayden S, Barton JJS, Feldman HH. PMID: 29620072; PMCID: PMC5874457.
      View in: PubMed   Mentions: 2  
    40. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. 2017 Jul 04; 89(1):88-100. McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. PMID: 28592453; PMCID: PMC5496518.
      View in: PubMed   Mentions: 1420     Fields:    Translation:Humans
    41. The Canadian dementia challenge: Ensuring optimal care and services for those at risk or with dementia throughout the country. Can J Public Health. 2017 04 20; 108(1):e95-e97. Feldman HH, Estabrooks CA. PMID: 28425906; PMCID: PMC6975213.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. The 2002 NIMH Provisional Diagnostic Criteria for Depression of Alzheimer's Disease (PDC-dAD): Gauging their Validity over a Decade Later. J Alzheimers Dis. 2017; 58(2):449-462. Sepehry AA, Lee PE, Hsiung GR, Beattie BL, Feldman HH, Jacova C. PMID: 28453472.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    43. Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial. Lancet. 2016 12 10; 388(10062):2873-2884. Gauthier S, Feldman HH, Schneider LS, Wilcock GK, Frisoni GB, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Wischik DJ, Schelter BO, Davis CS, Staff RT, Bracoud L, Shamsi K, Storey JM, Harrington CR, Wischik CM. PMID: 27863809; PMCID: PMC5164296.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansAnimalsCTClinical Trials
    44. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016 Aug 02; 87(5):539-47. Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. PMID: 27371494; PMCID: PMC4970664.
      View in: PubMed   Mentions: 752     Fields:    Translation:Humans
    45. Defeating Alzheimer's disease and other dementias: a priority for European science and society. Lancet Neurol. 2016 Apr; 15(5):455-532. Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, Iqbal K, Jessen F, Johansson G, Jönsson L, Kivipelto M, Knapp M, Mangialasche F, Melis R, Nordberg A, Rikkert MO, Qiu C, Sakmar TP, Scheltens P, Schneider LS, Sperling R, Tjernberg LO, Waldemar G, Wimo A, Zetterberg H. PMID: 26987701.
      View in: PubMed   Mentions: 600     Fields:    Translation:Humans
    46. Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. Alzheimers Dement. 2016 Mar; 12(3):292-323. Dubois B, Hampel H, Feldman HH, Scheltens P, Aisen P, Andrieu S, Bakardjian H, Benali H, Bertram L, Blennow K, Broich K, Cavedo E, Crutch S, Dartigues JF, Duyckaerts C, Epelbaum S, Frisoni GB, Gauthier S, Genthon R, Gouw AA, Habert MO, Holtzman DM, Kivipelto M, Lista S, Molinuevo JL, O'Bryant SE, Rabinovici GD, Rowe C, Salloway S, Schneider LS, Sperling R, Teichmann M, Carrillo MC, Cummings J, Jack CR, Proceedings of the Meeting of the International Working Group (IWG) and the American Alzheimer's Ass. PMID: 27012484; PMCID: PMC6417794.
      View in: PubMed   Mentions: 759     Fields:    Translation:HumansAnimals
    47. Periventricular hyperintensities are associated with elevated cerebral amyloid. Neurology. 2016 Feb 09; 86(6):535-43. Marnane M, Al-Jawadi OO, Mortazavi S, Pogorzelec KJ, Wang BW, Feldman HH, Hsiung GY, Alzheimer's Disease Neuroimaging Initiative. PMID: 26747881; PMCID: PMC4753726.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    48. Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study. Inhal Toxicol. 2016; 28(3):145-53. Cliff R, Curran J, Hirota JA, Brauer M, Feldman H, Carlsten C. PMID: 26915823.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    49. Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial. JAMA Neurol. 2015 Nov; 72(11):1324-33. Coric V, Salloway S, van Dyck CH, Dubois B, Andreasen N, Brody M, Curtis C, Soininen H, Thein S, Shiovitz T, Pilcher G, Ferris S, Colby S, Kerselaers W, Dockens R, Soares H, Kaplita S, Luo F, Pachai C, Bracoud L, Mintun M, Grill JD, Marek K, Seibyl J, Cedarbaum JM, Albright C, Feldman HH, Berman RM. PMID: 26414022.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCTClinical Trials
    50. Early neuropsychological characteristics of progranulin mutation carriers. J Int Neuropsychol Soc. 2014 Aug; 20(7):694-703. Hallam BJ, Jacova C, Hsiung GY, Wittenberg D, Sengdy P, Bouchard-Kerr P, Slack P, Rademakers R, Baker M, Chow TW, Levine B, Feldman HH, Mackenzie IR. PMID: 24993774.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    51. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. Lancet Neurol. 2014 Jun; 13(6):614-29. Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, DeKosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, Galasko D, Habert MO, Jicha GA, Nordberg A, Pasquier F, Rabinovici G, Robert P, Rowe C, Salloway S, Sarazin M, Epelbaum S, de Souza LC, Vellas B, Visser PJ, Schneider L, Stern Y, Scheltens P, Cummings JL. PMID: 24849862.
      View in: PubMed   Mentions: 1350     Fields:    Translation:Humans
    52. Alzheimer's disease research and development: a call for a new research roadmap. Ann N Y Acad Sci. 2014 Apr; 1313:1-16. Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS, One Mind for Research and the New York Academy of Sciences. PMID: 24754377.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    53. Evaluation of late-onset Alzheimer disease genetic susceptibility risks in a Canadian population. Neurobiol Aging. 2014 Apr; 35(4):936.e5-12. Omoumi A, Fok A, Greenwood T, Sadovnick AD, Feldman HH, Hsiung GY. PMID: 24176626.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    54. Anterior brain glucose hypometabolism predates dementia in progranulin mutation carriers. Neurology. 2013 Oct 08; 81(15):1322-31. Jacova C, Hsiung GY, Tawankanjanachot I, Dinelle K, McCormick S, Gonzalez M, Lee H, Sengdy P, Bouchard-Kerr P, Baker M, Rademakers R, Sossi V, Stoessl AJ, Feldman HH, Mackenzie IR. PMID: 24005336; PMCID: PMC3806924.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    55. Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: consensus from the Canadian conference on diagnosis of dementia. Alzheimers Res Ther. 2013 Jul 08; 5(Suppl 1):S2. Chertkow H, Feldman HH, Jacova C, Massoud F. PMID: 24565215; PMCID: PMC3981054.
      View in: PubMed   Mentions: 66     Fields:    
    56. Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimers Dement. 2013 Mar; 9(2):123-131.e1. Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. PMID: 23411394.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansPHPublic Health
    57. H.L. v. Matheson: where does the Court stand on abortion and parental notification? Am Univ Law Rev. 1982; 31(2):431-69. Feldman HN. PMID: 11658318.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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