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Kirk Knowlton

Title(s)Recall Faculty, Medicine
SchoolHealth Sciences
Address9300 Campus Point Drive #7411
La Jolla CA 92037
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    IVEM and Image Analysis Resource
    NIH/NCRR P41RR004050Aug 13, 2009 - Mar 31, 2014
    Role: Co-Investigator
    Role of mTOR, a Component of the Akt Pathway, in Regulating Cardiac Function
    NIH/NHLBI R01HL078797Dec 1, 2004 - Nov 30, 2014
    Role: Principal Investigator
    Dystrophin-glycoprotein complex in viral cardiomyopathy
    NIH/NHLBI R01HL066424Jul 1, 2001 - Jun 30, 2006
    Role: Principal Investigator
    Cardiac SOCS Proteins: A Role in Enterovirus Infection
    NIH/NHLBI R01HL057365Dec 5, 1998 - Nov 30, 2002
    Role: Principal Investigator
    MOLECULAR PHYSIOLOGY OF HEART FAILURE
    NIH/NHLBI P50HL053773Feb 1, 1995 - Feb 28, 2006
    Role: Co-Investigator
    Molecular Pathways for Hypertrophy and Cardiomyopathy
    NIH/NHLBI P01HL046345Feb 1, 1992 - Sep 30, 1997
    Role: Principal Investigator
    REGULATION OF ANF GENE DURING VENTRICULAR HYPERTROPHY
    NIH/NHLBI K08HL002618Aug 1, 1991 - Jul 31, 1997
    Role: Principal Investigator
    Training in Cardiovascular Physiology and Pharmacology
    NIH/NHLBI T32HL007444Jul 1, 1979 - Sep 29, 1990
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does not Alter Ventricular Function. Circ Res. 2020 Apr 29. Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, Chan Y, Li R, Peterson KL, Chen J, McCulloch AD, Knowlton KU, Ross RS. PMID: 32345129.
      View in: PubMed   Mentions:    Fields:    
    2. Predictors of Statin Intolerance in Patients with a New Diagnosis of Atherosclerotic Cardiovascular Disease Within a Large Integrated Healthcare Institution: The IMPRES Study. J Cardiovasc Pharmacol. 2020 Feb 17. Bair TL, May HT, Knowlton KU, Anderson JL, Lappe DL, Muhlestein JB. PMID: 32079856.
      View in: PubMed   Mentions:    Fields:    
    3. Absence of Coronary Artery Calcium During Positron Emission Tomography Stress Testing in Patients Without Known Coronary Artery Disease Identifies Individuals With Very Low Risk of Cardiac Events. Circ Cardiovasc Imaging. 2020 Jan; 13(1):e009907. Le VT, Knight S, Min DB, McCubrey RO, Horne BD, Jensen KR, Meredith KG, Mason SM, Lappé DL, Anderson JL, Muhlestein JB, Knowlton KU. PMID: 31959008.
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    4. Free thyroxine within the normal reference range predicts risk of atrial fibrillation. J Cardiovasc Electrophysiol. 2020 Jan; 31(1):18-29. Anderson JL, Jacobs V, May HT, Bair TL, Benowitz BA, Lappe DL, Muhlestein JB, Knowlton KU, Bunch TJ. PMID: 31515856.
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    5. Comparison of Three Atherosclerotic Cardiovascular Disease Risk Scores With and Without Coronary Calcium for Predicting Revascularization and Major Adverse Coronary Events in Symptomatic Patients Undergoing Positron Emission Tomography-Stress Testing. Am J Cardiol. 2020 02 01; 125(3):341-348. Anderson JL, Le VT, Min DB, Biswas S, Minder CM, McCubrey RO, Knight S, Horne BD, Mason S, Lappe DL, Muhlestein JB, Knowlton KU. PMID: 31806210.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Value of Neutrophil to Lymphocyte Ratio and Its Trajectory in Patients Hospitalized With Acute Heart Failure and Preserved Ejection Fraction. Am J Cardiol. 2020 01 15; 125(2):229-235. Boralkar KA, Kobayashi Y, Amsallem M, Ataam JA, Moneghetti KJ, Cauwenberghs N, Horne BD, Knowlton KU, Maecker H, Kuznetsova T, Heidenreich PA, Haddad F. PMID: 31753313.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Circulating Levels of Biomarkers of Cerebral Injury in Patients with Atrial Fibrillation. Am J Cardiol. 2019 12 01; 124(11):1697-1700. Galenko O, Jacobs V, Knight S, Bride D, Cutler MJ, Muhlestein JB, Carlquist JL, Anderson JL, Knowlton KU, Jared Bunch T. PMID: 31575426.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Approaching Higher Dimension Imaging Data Using Cluster-Based Hierarchical Modeling in Patients with Heart Failure Preserved Ejection Fraction. Sci Rep. 2019 07 18; 9(1):10431. Kobayashi Y, Tremblay-Gravel M, Boralkar KA, Li X, Nishi T, Amsallem M, Moneghetti KJ, Bouajila S, Selej M, Ozen MO, Demirci U, Ashley E, Wheeler M, Knowlton KU, Kouznetsova T, Haddad F. PMID: 31320698.
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    9. Improving risk stratification in heart failure with preserved ejection fraction by combining two validated risk scores. Open Heart. 2019; 6(1):e000961. Boralkar KA, Kobayashi Y, Moneghetti KJ, Pargaonkar VS, Tuzovic M, Krishnan G, Wheeler MT, Banerjee D, Kuznetsova T, Horne BD, Knowlton KU, Heidenreich PA, Haddad F. PMID: 31217994.
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    10. Dilated Cardiomyopathy. Circulation. 2019 05 14; 139(20):2339-2341. Knowlton KU. PMID: 31082299.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture. Circulation. 2019 03 19; 139(12):1554-1556. Zhang Z, Mu Y, Zhang J, Zhou Y, Cattaneo P, Veevers J, Peter AK, Manso AM, Knowlton KU, Zhou X, Evans SM, Ross RS, Chen J. PMID: 30883226.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Safety and Efficacy of Periprocedural Heparin Plus a Short-Term Infusion of Tirofiban Versus Bivalirudin Monotherapy in Patients Who Underwent Percutaneous Coronary Intervention (from the Intermountain Heart Institute STAIR Observational Registry). Am J Cardiol. 2019 06 15; 123(12):1927-1934. Muhlestein JB, Hackett IS, May HT, Bair TL, Le VT, Anderson JL, Whisenant B, Knowlton KU, Lappé DL. PMID: 30981419.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. The role of microRNAs in the development, regulation, and treatment of atrial fibrillation. J Interv Card Electrophysiol. 2019 Sep; 55(3):297-305. Galenko O, Jacobs V, Knight S, Taylor M, Cutler MJ, Muhlestein JB, Carlquist JL, Knowlton KU, Jared Bunch T. PMID: 30607665.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. CHA2DS2-VASc scores and Intermountain Mortality Risk Scores for the joint risk stratification of dementia among patients with atrial fibrillation. Heart Rhythm. 2019 01; 16(1):3-9. Graves KG, May HT, Jacobs V, Knowlton KU, Muhlestein JB, Lappe DL, Anderson JL, Horne BD, Bunch TJ. PMID: 30611392.
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    15. Prediction of Long-Term Incidence of Chronic Cardiovascular and Cardiopulmonary Diseases in Primary Care Patients for Population Health Monitoring: The Intermountain Chronic Disease Model (ICHRON). Mayo Clin Proc. 2019 07; 94(7):1221-1230. May HT, Lappé DL, Knowlton KU, Muhlestein JB, Anderson JL, Horne BD. PMID: 30577973.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Improving CHA2DS2-VASc stratification of non-fatal stroke and mortality risk using the Intermountain Mortality Risk Score among patients with atrial fibrillation. Open Heart. 2018; 5(2):e000907. Graves KG, May HT, Knowlton KU, Muhlestein JB, Jacobs V, Lappé DL, Anderson JL, Horne BD, Bunch TJ. PMID: 30564375.
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    17. Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports. 2018 09 11; 11(3):828-841. Veevers J, Farah EN, Corselli M, Witty AD, Palomares K, Vidal JG, Emre N, Carson CT, Ouyang K, Liu C, van Vliet P, Zhu M, Hegarty JM, Deacon DC, Grinstein JD, Dirschinger RJ, Frazer KA, Adler ED, Knowlton KU, Chi NC, Martin JC, Chen J, Evans SM. PMID: 30122443.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    18. Extreme erythrocyte macrocytic and microcytic percentages are highly predictive of morbidity and mortality. JCI Insight. 2018 07 26; 3(14). Horne BD, Muhlestein JB, Bennett ST, Muhlestein JB, Jensen KR, Marshall D, Bair TL, May HT, Carlquist JF, Hegewald M, Knight S, Le VT, Bunch TJ, Lappé DL, Anderson JL, Knowlton KU. PMID: 30046011.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. How Community-Based Health Systems Can Embrace Research in the Fee-for-Value Era. Qual Manag Health Care. 2018 Jul/Sep; 27(3):180-182. Knighton AJ, Grissom CK, Knowlton KU, Sean Esplin M, Graydon T, Srivastava R. PMID: 29944632.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Implementation of a cardiac PET stress program: comparison of outcomes to the preceding SPECT era. JCI Insight. 2018 05 03; 3(9). Knight S, Min DB, Le VT, Meredith KG, Dhar R, Biswas S, Jensen KR, Mason SM, Ethington JD, Lappe DL, Muhlestein JB, Anderson JL, Knowlton KU. PMID: 29720565.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. GlycA and hsCRP are independent and additive predictors of future cardiovascular events among patients undergoing angiography: The intermountain heart collaborative study. Am Heart J. 2018 08; 202:27-32. Muhlestein JB, May HT, Galenko O, Knowlton KU, Otvos JD, Connelly MA, Lappe DL, Anderson JL. PMID: 29803983.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Temporal changes in statin prescription and intensity at discharge and impact on outcomes in patients with newly diagnosed atherosclerotic cardiovascular disease-Real-world experience within a large integrated health care system: The IMPRES study. J Clin Lipidol. 2018 Jul - Aug; 12(4):1008-1018.e1. Anderson JL, Knowlton KU, May HT, Bair TL, Armstrong SO, Lappé DL, Muhlestein JB. PMID: 29703626.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    23. Real world MRI experience with nonconditional and conditional cardiac rhythm devices after MagnaSafe. J Cardiovasc Electrophysiol. 2017 Dec; 28(12):1468-1474. Mason S, Osborn JS, Dhar R, Tonkin A, Ethington JD, Le V, Benuzillo J, Lappe DL, Knowlton KU, Bunch TJ, Anderson JL. PMID: 28960745.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. The association of depression at any time to the risk of death following coronary artery disease diagnosis. Eur Heart J Qual Care Clin Outcomes. 2017 10 01; 3(4):296-302. May HT, Horne BD, Knight S, Knowlton KU, Bair TL, Lappé DL, Le VT, Muhlestein JB. PMID: 28950317.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Myocarditis: An Intersection Between Genetic and Acquired Causes of Human Cardiomyopathy. J Am Coll Cardiol. 2017 04 04; 69(13):1666-1668. Knowlton KU. PMID: 28359510.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Increased Echogenicity and Radiodense Foci on Echocardiogram and MicroCT in Murine Myocarditis. PLoS One. 2016; 11(8):e0159971. Peter AK, Bradford WH, Dalton ND, Gu Y, Chao CJ, Peterson KL, Knowlton KU. PMID: 27486657.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    27. Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure. Circ Heart Fail. 2016 08; 9(8). Zhang Z, Mu Y, Veevers J, Peter AK, Manso AM, Bradford WH, Dalton ND, Peterson KL, Knowlton KU, Ross RS, Zhou X, Chen J. PMID: 27502369.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    28. Lmo7 is dispensable for skeletal muscle and cardiac function. Am J Physiol Cell Physiol. 2015 Oct 01; 309(7):C470-9. Lao DH, Esparza MC, Bremner SN, Banerjee I, Zhang J, Veevers J, Bradford WH, Gu Y, Dalton ND, Knowlton KU, Peterson KL, Lieber RL, Chen J. PMID: 26157009.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    29. Prevalence of coronary artery-pulmonary artery collaterals in patients with chronic thromboembolic pulmonary hypertension. Pulm Circ. 2015 Jun; 5(2):313-21. Lee NS, Blanchard DG, Knowlton KU, McDivit AM, Pretorius V, Madani MM, Fedullo PF, Kerr KM, Kim NH, Poch DS, Auger WR, Daniels LB. PMID: 26064456.
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    30. Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy. J Clin Invest. 2013 Dec; 123(12):5146-51. Lim BK, Peter AK, Xiong D, Narezkina A, Yung A, Dalton ND, Hwang KK, Yajima T, Chen J, Knowlton KU. PMID: 24200690.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    31. Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction. J Am Coll Cardiol. 2012 Feb 28; 59(9):838-52. Oba T, Yasukawa H, Hoshijima M, Sasaki K, Futamata N, Fukui D, Mawatari K, Nagata T, Kyogoku S, Ohshima H, Minami T, Nakamura K, Kang D, Yajima T, Knowlton KU, Imaizumi T. PMID: 22361405.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    32. Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19413-8. Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B. PMID: 22087007.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    33. Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. Circulation. 2011 Dec 13; 124(24):2690-701. Yajima T, Murofushi Y, Zhou H, Park S, Housman J, Zhong ZH, Nakamura M, Machida M, Hwang KK, Gu Y, Dalton ND, Yajima T, Yasukawa H, Peterson KL, Knowlton KU. PMID: 22082679.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    34. The costamere bridges sarcomeres to the sarcolemma in striated muscle. Prog Pediatr Cardiol. 2011 May; 31(2):83-88. Peter AK, Cheng H, Ross RS, Knowlton KU, Chen J. PMID: 24039381.
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    35. Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet. 2011 May 01; 20(9):1751-62. Cheng H, Zheng M, Peter AK, Kimura K, Li X, Ouyang K, Shen T, Cui L, Frank D, Dalton ND, Gu Y, Frey N, Peterson KL, Evans SM, Knowlton KU, Sheikh F, Chen J. PMID: 21303826.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    36. Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res. 2010 Aug 06; 107(3):348-56. Cheng H, Kimura K, Peter AK, Cui L, Ouyang K, Shen T, Liu Y, Gu Y, Dalton ND, Evans SM, Knowlton KU, Peterson KL, Chen J. PMID: 20538684.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    37. Viral myocarditis: from the perspective of the virus. Circulation. 2009 May 19; 119(19):2615-24. Yajima T, Knowlton KU. PMID: 19451363.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    38. Viral myocarditis: is infection of the heart required? J Am Coll Cardiol. 2009 Apr 07; 53(14):1227-8. Knowlton KU, Lim BK. PMID: 19341865.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    39. Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest. 2008 Aug; 118(8):2758-70. Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU. PMID: 18636119.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    40. CVB infection and mechanisms of viral cardiomyopathy. Curr Top Microbiol Immunol. 2008; 323:315-35. Knowlton KU. PMID: 18357777.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    41. Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H69-76. Wang YX, da Cunha V, Vincelette J, White K, Velichko S, Xu Y, Gross C, Fitch RM, Halks-Miller M, Larsen BR, Yajima T, Knowlton KU, Vergona R, Sullivan ME, Croze E. PMID: 17434974.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    42. Inducible cardiac-restricted expression of enteroviral protease 2A is sufficient to induce dilated cardiomyopathy. Circulation. 2007 Jan 02; 115(1):94-102. Xiong D, Yajima T, Lim BK, Stenbit A, Dublin A, Dalton ND, Summers-Torres D, Molkentin JD, Duplain H, Wessely R, Chen J, Knowlton KU. PMID: 17190866.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    43. Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling. Circulation. 2006 Nov 28; 114(22):2364-73. Yajima T, Yasukawa H, Jeon ES, Xiong D, Dorner A, Iwatate M, Nara M, Zhou H, Summers-Torres D, Hoshijima M, Chien KR, Yoshimura A, Knowlton KU. PMID: 17101849.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    44. alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation. 2006 Sep 05; 114(10):1046-55. Sheikh F, Chen Y, Chen Y, Liang X, Hirschy A, Stenbit AE, Gu Y, Dalton ND, Yajima T, Lu Y, Knowlton KU, Peterson KL, Perriard JC, Chen J. PMID: 16923756.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    45. Prion-induced amyloid heart disease with high blood infectivity in transgenic mice. Science. 2006 Jul 07; 313(5783):94-7. Trifilo MJ, Yajima T, Gu Y, Dalton N, Peterson KL, Race RE, Meade-White K, Portis JL, Masliah E, Knowlton KU, Chesebro B, Oldstone MB. PMID: 16825571.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    46. Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle. J Cell Biol. 2006 Jun 19; 173(6):905-16. Bang ML, Li X, Littlefield R, Bremner S, Thor A, Knowlton KU, Lieber RL, Chen J. PMID: 16769824.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    47. Unsolved medical issues and new targets for further research in viral myocarditis and dilated cardiomyopathy. Ernst Schering Res Found Workshop. 2006; (55):19-35. Knowlton KU. PMID: 16329655.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    48. Long-term cardiac gene expression using a coxsackieviral vector. J Mol Cell Cardiol. 2005 May; 38(5):745-51. Lim BK, Shin JO, Lee SC, Kim DK, Choi DJ, Choe SC, Knowlton KU, Jeon ES. PMID: 15850568.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    49. Highlights of the year in JACC 2004. J Am Coll Cardiol. 2005 Jan 04; 45(1):137-53. Demaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Narula J, Sahn D, Tsimikas S. PMID: 15629388.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    50. Interleukin-10: biomarker or pathologic cytokine in fulminant myocarditis? J Am Coll Cardiol. 2004 Sep 15; 44(6):1298-300. Knowlton KU, Yajima T. PMID: 15364335.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Chronic thromboembolic pulmonary hypertension. Cardiol Clin. 2004 Aug; 22(3):453-66, vii. Auger WR, Kerr KM, Kim NH, Ben-Yehuda O, Knowlton KU, Fedullo PF. PMID: 15302364.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    52. Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection. J Biol Chem. 2004 Apr 30; 279(18):18497-503. Dörner A, Xiong D, Couch K, Yajima T, Knowlton KU. PMID: 14978041.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    53. Preoperative partitioning of pulmonary vascular resistance correlates with early outcome after thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Circulation. 2004 Jan 06; 109(1):18-22. Kim NH, Fesler P, Channick RN, Knowlton KU, Ben-Yehuda O, Lee SH, Naeije R, Rubin LJ. PMID: 14699009.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    54. Highlights of the year in JACC 2003. J Am Coll Cardiol. 2003 Dec 17; 42(12):2156-66. DeMaria AN, Ben-Yehuda O, Berman D, Feld GK, Greenberg BH, Knoke JD, Knowlton KU, Lew WY, Tsimikas S. PMID: 15560019.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. Dystrophin disruption in enterovirus-induced myocarditis and dilated cardiomyopathy: from bench to bedside. Med Microbiol Immunol. 2004 May; 193(2-3):121-6. Badorff C, Knowlton KU. PMID: 12920582.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. Electrocardiographic manifestations: wide complex tachycardia due to accessory pathway. J Emerg Med. 2003 Apr; 24(3):295-301. Nelson JA, Knowlton KU, Harrigan R, Pollack ML, Chan TC. PMID: 12676301.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    57. The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury. J Clin Invest. 2003 Feb; 111(4):469-78. Yasukawa H, Yajima T, Duplain H, Iwatate M, Kido M, Hoshijima M, Weitzman MD, Nakamura T, Woodard S, Xiong D, Yoshimura A, Chien KR, Knowlton KU. PMID: 12588885.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    58. Protection of cap-dependent protein synthesis in vivo and in vitro with an eIF4G-1 variant highly resistant to cleavage by Coxsackievirus 2A protease. J Biol Chem. 2003 Feb 14; 278(7):4449-57. Zhao X, Lamphear BJ, Xiong D, Knowlton K, Rhoads RE. PMID: 12475969.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    59. Dystrophin deficiency markedly increases enterovirus-induced cardiomyopathy: a genetic predisposition to viral heart disease. Nat Med. 2002 Aug; 8(8):872-7. Xiong D, Lee GH, Badorff C, Dorner A, Lee S, Wolf P, Knowlton KU. PMID: 12118246.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    60. Apoptosis and oncosis in the early progression of left ventricular dysfunction in the cardiomyopathic hamster. Basic Res Cardiol. 2002 Jan; 97(1):65-75. Ryoke T, Gu Y, Ikeda Y, Martone ME, Oh SS, Jeon ES, Knowlton KU, Ross J. PMID: 12004790.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    61. A mutation in the puff region of VP2 attenuates the myocarditic phenotype of an infectious cDNA of the Woodruff variant of coxsackievirus B3. J Virol. 1996 Nov; 70(11):7811-8. Knowlton KU, Jeon ES, Berkley N, Wessely R, Huber S. PMID: 8892902.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
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