Cornelis Murre

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    FASEB SRC on Molecular Mechanisms of Immune Cell Development and Function
    NIH R13AI131593Jun 1, 2017 - May 31, 2018
    Role: Principal Investigator
    San Diego Center for 4D Nucleome Research
    NIH U54DK107977Sep 30, 2015 - Jul 31, 2021
    Role: Principal Investigator
    Molecular Basis for gamma/delta T Lineage Specification
    NIH P01AI102853May 15, 2014 - Apr 30, 2019
    Role: Co-Investigator
    E-proteins and EBF1 in B cell differentiation
    NIH R01AI109599Apr 15, 2014 - Mar 31, 2020
    Role: Principal Investigator
    FASEB SRC on Molecular Mechanisms of Immune Cell Development and Function
    NIH R13AI106088Jun 1, 2013 - May 31, 2014
    Role: Principal Investigator
    The 3D-Structures of the Pre-Pro-B and Pro-B Cell Genomes
    NIH R01AI100880May 1, 2012 - Apr 30, 2023
    Role: Principal Investigator
    The 3D-Structures of the Immunoglobulin Heavy Chain Locus
    NIH R01AI082850Mar 1, 2009 - Feb 28, 2025
    Role: Principal Investigator
    Molecular Pathways to T-Lineage Commitment
    NIH R01AI062770Dec 1, 2004 - Nov 30, 2010
    Role: Principal Investigator
    E2A as a Tumor Suppressor
    NIH R01CA078384Apr 1, 1999 - Jan 31, 2014
    Role: Principal Investigator
    NIH R01CA065797Dec 8, 1994 - Nov 30, 2004
    Role: Principal Investigator
    The role of E-proteins in B cell development
    NIH R01CA054198Apr 1, 1991 - Feb 28, 2014
    Role: Principal Investigator
    NIH R37CA054198Apr 1, 1991 - Jan 31, 2009
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nuclear morphology is shaped by loop-extrusion programs. Nature. 2024 Mar; 627(8002):196-203. Patta I, Zand M, Lee L, Mishra S, Bortnick A, Lu H, Prusty A, McArdle S, Mikulski Z, Wang HY, Cheng CS, Fisch KM, Hu M, Murre C. PMID: 38355805.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Active maintenance of CD8+ T cell naivety through regulation of global genome architecture. Cell Rep. 2023 10 31; 42(10):113301. Russ BE, Barugahare A, Dakle P, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, Kallies A, Murre C, Collas P, Powell D, Goldrath AW, Turner SJ. PMID: 37858463; PMCID: PMC10679840.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    3. Transcriptional network governing extraembryonic endoderm cell fate choice. Dev Biol. 2023 10; 502:20-37. Pham PD, Lu H, Han H, Zhou JJ, Madan A, Wang W, Murre C, Cho KWY. PMID: 37423592; PMCID: PMC10550205.
      View in: PubMed   Mentions:    Fields:    
    4. Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture. bioRxiv. 2023 Feb 27. Russ BE, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, Barugahare A, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, Kallies A, Murre C, Collas P, Powell D, Goldrath AW, Turner SJ. PMID: 36909629; PMCID: PMC10002700.
      View in: PubMed   Mentions:
    5. Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens. Nat Immunol. 2023 02; 24(2):320-336. Barajas-Mora EM, Lee L, Lu H, Valderrama JA, Bjanes E, Nizet V, Feeney AJ, Hu M, Murre C. PMID: 36717722; PMCID: PMC10917333.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    6. A proposed unified interphase nucleus chromosome structure: Preliminary preponderance of evidence. Proc Natl Acad Sci U S A. 2022 06 28; 119(26):e2119101119. Sedat J, McDonald A, Cang H, Lucas J, Arigovindan M, Kam Z, Murre C, Elbaum M. PMID: 35749363; PMCID: PMC9245672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Helix-Loop-Helix Proteins in Adaptive Immune Development. Front Immunol. 2022; 13:881656. Aubrey M, Warburg ZJ, Murre C. PMID: 35634342; PMCID: PMC9134016.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. A proposed unified mitotic chromosome architecture. Proc Natl Acad Sci U S A. 2022 05 17; 119(20):e2119107119. Sedat J, McDonald A, Kasler H, Verdin E, Cang H, Arigovindan M, Murre C, Elbaum M. PMID: 35544689; PMCID: PMC9171755.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Bursty gene expression and mRNA decay pathways orchestrate B cell activation. Sci Adv. 2021 Dec 03; 7(49):eabm0819. Zhou Y, Murre C. PMID: 34860551; PMCID: PMC8641932.
      View in: PubMed   Mentions: 3     Fields:    
    10. A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes. Proc Natl Acad Sci U S A. 2021 11 16; 118(46). Nikhat S, Yadavalli AD, Prusty A, Narayan PK, Palakodeti D, Murre C, Pongubala JMR. PMID: 34750254; PMCID: PMC8609617.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development. Front Immunol. 2021; 12:633825. Pongubala JMR, Murre C. PMID: 33854505; PMCID: PMC8039525.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    12. The E protein-TCF1 axis controls γδ T cell development and effector fate. Cell Rep. 2021 02 02; 34(5):108716. Fahl SP, Contreras AV, Verma A, Qiu X, Harly C, Radtke F, Zúñiga-Pflücker JC, Murre C, Xue HH, Sen JM, Wiest DL. PMID: 33535043; PMCID: PMC7919611.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    13. FOXO1 constrains activation and regulates senescence in CD8 T cells. Cell Rep. 2021 01 26; 34(4):108674. Delpoux A, Marcel N, Hess Michelini R, Katayama CD, Allison KA, Glass CK, Quiñones-Parra SM, Murre C, Loh L, Kedzierska K, Lappas M, Hedrick SM, Doedens AL. PMID: 33503413.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    14. Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization. Genes Dev. 2021 01 01; 35(1-2):65-81. Zhu Y, Denholtz M, Lu H, Murre C. PMID: 33334824; PMCID: PMC7778268.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    15. Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses. Sci Immunol. 2020 08 21; 5(50). Boland BS, He Z, Tsai MS, Olvera JG, Omilusik KD, Duong HG, Kim ES, Limary AE, Jin W, Milner JJ, Yu B, Patel SA, Louis TL, Tysl T, Kurd NS, Bortnick A, Quezada LK, Kanbar JN, Miralles A, Huylebroeck D, Valasek MA, Dulai PS, Singh S, Lu LF, Bui JD, Murre C, Sandborn WJ, Goldrath AW, Yeo GW, Chang JT. PMID: 32826341; PMCID: PMC7733868.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    16. Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. Cell Rep. 2020 Jun 30; 31(13):107876. Bortnick A, He Z, Aubrey M, Chandra V, Denholtz M, Chen K, Lin YC, Murre C. PMID: 32610145.
      View in: PubMed   Mentions: 2     Fields:    
    17. Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing. Sci Immunol. 2020 05 15; 5(47). Kurd NS, He Z, Louis TL, Milner JJ, Omilusik KD, Jin W, Tsai MS, Widjaja CE, Kanbar JN, Olvera JG, Tysl T, Quezada LK, Boland BS, Huang WJ, Murre C, Goldrath AW, Yeo GW, Chang JT. PMID: 32414833; PMCID: PMC7341730.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    18. Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. Cell Rep. 2020 04 07; 31(1):107470. Bortnick A, He Z, Aubrey M, Chandra V, Denholtz M, Chen K, Lin YC, Murre C. PMID: 32268089; PMCID: PMC10871151.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program. Genes Dev. 2020 02 01; 34(3-4):149-165. Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C. PMID: 31919189; PMCID: PMC7000913.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    20. Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18423-18428. Xu H, Tong Z, Ye Q, Sun T, Hong Z, Zhang L, Bortnick A, Cho S, Beuzer P, Axelrod J, Hu Q, Wang M, Evans SM, Murre C, Lu LF, Sun S, Corbett KD, Cang H. PMID: 31444302; PMCID: PMC6744910.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    21. Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions. Nat Commun. 2019 06 24; 10(1):2771. Khanna N, Zhang Y, Lucas JS, Dudko OK, Murre C. PMID: 31235807; PMCID: PMC6591236.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    22. CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10927-10936. Arends T, Dege C, Bortnick A, Danhorn T, Knapp JR, Jia H, Harmacek L, Fleenor CJ, Straign D, Walton K, Leach SM, Feeney AJ, Murre C, O'Connor BP, Hagman JR. PMID: 31085655; PMCID: PMC6561196.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    23. Helix-loop-helix proteins and the advent of cellular diversity: 30 years of discovery. Genes Dev. 2019 01 01; 33(1-2):6-25. Murre C. PMID: 30602438; PMCID: PMC6317319.
      View in: PubMed   Mentions: 57     Fields:    Translation:Cells
    24. A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire. Mol Cell. 2019 01 03; 73(1):48-60.e5. Barajas-Mora EM, Kleiman E, Xu J, Carrico NC, Lu H, Oltz EM, Murre C, Feeney AJ. PMID: 30449725; PMCID: PMC6610861.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    25. mTECs Aire on the side of caution. Nat Immunol. 2018 02; 19(2):100-101. Bortnick A, Murre C. PMID: 29348498.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    26. Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection. Front Immunol. 2018; 9:42. Roy S, Moore AJ, Love C, Reddy A, Rajagopalan D, Dave SS, Li L, Murre C, Zhuang Y. PMID: 29416542; PMCID: PMC5787561.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    27. 'Big bang' of B-cell development revealed. Genes Dev. 2018 01 15; 32(2):93-95. Murre C. PMID: 29449365; PMCID: PMC5830931.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    28. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017 Sep 21; 171(1):103-119.e18. Isoda T, Moore AJ, He Z, Chandra V, Aida M, Denholtz M, Piet van Hamburg J, Fisch KM, Chang AN, Fahl SP, Wiest DL, Murre C. PMID: 28938112; PMCID: PMC5621651.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    29. CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs. Immunity. 2017 08 15; 47(2):251-267.e7. Chisolm DA, Savic D, Moore AJ, Ballesteros-Tato A, León B, Crossman DK, Murre C, Myers RM, Weinmann AS. PMID: 28813658; PMCID: PMC5654635.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    30. The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development. Immunity. 2017 05 16; 46(5):818-834.e4. Miyazaki M, Miyazaki K, Chen K, Jin Y, Turner J, Moore AJ, Saito R, Yoshida K, Ogawa S, Rodewald HR, Lin YC, Kawamoto H, Murre C. PMID: 28514688; PMCID: PMC5512722.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    31. Comprehensive characterization of neutrophil genome topology. Genes Dev. 2017 01 15; 31(2):141-153. Zhu Y, Gong K, Denholtz M, Chandra V, Kamps MP, Alber F, Murre C. PMID: 28167501; PMCID: PMC5322729.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    32. Id3 Orchestrates Germinal Center B Cell Development. Mol Cell Biol. 2016 10 15; 36(20):2543-52. Chen S, Miyazaki M, Chandra V, Fisch KM, Chang AN, Murre C. PMID: 27457619; PMCID: PMC5038142.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCellsPHPublic Health
    33. A Common Mechanism that Underpins Antibody Diversification. Cell. 2015 Nov 19; 163(5):1055-1056. Murre C. PMID: 26590414.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    34. Cellular and chromatin dynamics of antibody-secreting plasma cells. Wiley Interdiscip Rev Dev Biol. 2016 Mar-Apr; 5(2):136-49. Bortnick A, Murre C. PMID: 26488117; PMCID: PMC4761274.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    35. New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12776-81. Benner C, Isoda T, Murre C. PMID: 26417104; PMCID: PMC4611620.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    36. Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci. Nucleic Acids Res. 2016 Jan 08; 44(1):175-86. Rother MB, Palstra RJ, Jhunjhunwala S, van Kester KA, van IJcken WF, Hendriks RW, van Dongen JJ, Murre C, van Zelm MC. PMID: 26384565; PMCID: PMC4705691.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    37. AID targeting: old mysteries and new challenges. Trends Immunol. 2015 Sep; 36(9):527-35. Chandra V, Bortnick A, Murre C. PMID: 26254147; PMCID: PMC4567449.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    38. The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth. Nat Immunol. 2015 Jul; 16(7):775-84. Bossen C, Murre CS, Chang AN, Mansson R, Rodewald HR, Murre C. PMID: 25985234; PMCID: PMC4474778.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    39. The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis. Genes Dev. 2015 Feb 15; 29(4):409-25. Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, Rodewald HR, Saito R, Chang AN, Varki N, Kawamoto H, Murre C. PMID: 25691468; PMCID: PMC4335296.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    40. Ensuring an equal playing field for antigen receptor loci variable regions. J Exp Med. 2015 Jan 12; 212(1):2. Murre C. PMID: 25582312; PMCID: PMC4291535.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    41. Preface. Adv Immunol. 2015; 128:xi-xii. Murre C. PMID: 26477372.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    42. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 2014 Dec 18; 159(7):1524-37. Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R. PMID: 25483777; PMCID: PMC4272762.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansAnimalsCells
    43. 3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions. Cell. 2014 Jul 17; 158(2):339-352. Lucas JS, Zhang Y, Dudko OK, Murre C. PMID: 24998931; PMCID: PMC4113018.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    44. Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Nat Immunol. 2014 Aug; 15(8):767-76. Miyazaki M, Miyazaki K, Chen S, Itoi M, Miller M, Lu LF, Varki N, Chang AN, Broide DH, Murre C. PMID: 24973820; PMCID: PMC4365819.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    45. The establishment of B versus T cell identity. Trends Immunol. 2014 May; 35(5):205-10. Miyazaki K, Miyazaki M, Murre C. PMID: 24679436; PMCID: PMC4030559.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    46. A HESitant decision for T cells. Nat Immunol. 2013 Dec; 14(12):1209-10. Bortnick A, Murre C. PMID: 24240153.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    47. The epigenetics of early lymphocyte development. Cold Spring Harb Symp Quant Biol. 2013; 78:43-9. Murre C. PMID: 24092471.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    48. Boosting lymphocyte production. Immunity. 2013 Jun 27; 38(6):1081-3. Murre C. PMID: 23809155.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    49. Nuclear location and the control of developmental progression. Curr Opin Genet Dev. 2013 Apr; 23(2):104-8. Lin YC, Murre C. PMID: 23266214; PMCID: PMC3613431.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    50. Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21028-33. Mansson R, Welinder E, Åhsberg J, Lin YC, Benner C, Glass CK, Lucas JS, Sigvardsson M, Murre C. PMID: 23213261; PMCID: PMC3529039.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    51. β-Selection-induced proliferation is required for αβ T cell differentiation. Immunity. 2012 Nov 16; 37(5):840-53. Kreslavsky T, Gleimer M, Miyazaki M, Choi Y, Gagnon E, Murre C, Sicinski P, von Boehmer H. PMID: 23159226; PMCID: PMC3709258.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    52. Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol. 2012 Dec; 13(12):1196-204. Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C. PMID: 23064439; PMCID: PMC3501570.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    53. E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus. J Immunol. 2012 Jun 01; 188(11):5547-60. Sakamoto S, Wakae K, Anzai Y, Murai K, Tamaki N, Miyazaki M, Miyazaki K, Romanow WJ, Ikawa T, Kitamura D, Yanagihara I, Minato N, Murre C, Agata Y. PMID: 22544934.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    54. Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47. Mol Cell Biol. 2012 May; 32(9):1671-82. Teachenor R, Beck K, Wright LY, Shen Z, Briggs SP, Murre C. PMID: 22354994; PMCID: PMC3347234.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    55. Chromatin topology and the regulation of antigen receptor assembly. Annu Rev Immunol. 2012; 30:337-56. Bossen C, Mansson R, Murre C. PMID: 22224771.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    56. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol. 2011 Nov 06; 12(12):1221-9. Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW. PMID: 22057289; PMCID: PMC3872000.
      View in: PubMed   Mentions: 241     Fields:    Translation:AnimalsCells
    57. The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17402-7. Welinder E, Mansson R, Mercer EM, Bryder D, Sigvardsson M, Murre C. PMID: 21972416; PMCID: PMC3198373.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    58. Factors and networks that underpin early hematopoiesis. Semin Immunol. 2011 Oct; 23(5):317-25. Mercer EM, Lin YC, Murre C. PMID: 21930392; PMCID: PMC3217090.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    59. CTCF-binding elements mediate control of V(D)J recombination. Nature. 2011 Sep 11; 477(7365):424-30. Guo C, Yoon HS, Franklin A, Jain S, Ebert A, Cheng HL, Hansen E, Despo O, Bossen C, Vettermann C, Bates JG, Richards N, Myers D, Patel H, Gallagher M, Schlissel MS, Murre C, Busslinger M, Giallourakis CC, Alt FW. PMID: 21909113; PMCID: PMC3342812.
      View in: PubMed   Mentions: 164     Fields:    Translation:AnimalsCells
    60. Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity. 2011 Sep 23; 35(3):413-25. Mercer EM, Lin YC, Benner C, Jhunjhunwala S, Dutkowski J, Flores M, Sigvardsson M, Ideker T, Glass CK, Murre C. PMID: 21903424; PMCID: PMC3183365.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    61. The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells. Nat Immunol. 2011 Aug 21; 12(10):992-1001. Miyazaki M, Rivera RR, Miyazaki K, Lin YC, Agata Y, Murre C. PMID: 21857655; PMCID: PMC3178719.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    62. CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci U S A. 2011 Jun 07; 108(23):9566-71. Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork NJ, Schlissel MS, Riblet R, Murre C, Feeney AJ. PMID: 21606361; PMCID: PMC3111298.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    63. Ldb1, a new guardian of hematopoietic stem cell maintenance. Nat Immunol. 2011 Feb; 12(2):113-4. Welinder E, Murre C. PMID: 21245899.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    64. Transcription and recombination factories: common features? Curr Opin Cell Biol. 2011 Jun; 23(3):318-24. Lucas JS, Bossen C, Murre C. PMID: 21169003; PMCID: PMC3070187.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    65. Global approaches to identify novel participants that modulate intestinal epithelial cell development. Dev Cell. 2010 Nov 16; 19(5):647-8. Murre C. PMID: 21074714.
      View in: PubMed   Mentions:    Fields:    
    66. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol. 2010 Jul; 11(7):635-43. Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C. PMID: 20543837; PMCID: PMC2896911.
      View in: PubMed   Mentions: 298     Fields:    Translation:AnimalsCells
    67. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell. 2010 May 28; 38(4):576-89. Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. PMID: 20513432; PMCID: PMC2898526.
      View in: PubMed   Mentions: 6181     Fields:    Translation:AnimalsCells
    68. Current Opinion in Immunology. Editorial overview. Curr Opin Immunol. 2010 Apr; 22(2):145-7. Rothenberg EV, Murre C. PMID: 20303722.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    69. Developmental trajectories in early hematopoiesis. Genes Dev. 2009 Oct 15; 23(20):2366-70. Murre C. PMID: 19833763; PMCID: PMC2764501.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    70. Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. J Exp Med. 2009 Sep 28; 206(10):2271-84. Beck K, Peak MM, Ota T, Nemazee D, Murre C. PMID: 19752184; PMCID: PMC2757879.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    71. Chromatin architecture and the generation of antigen receptor diversity. Cell. 2009 Aug 07; 138(3):435-48. Jhunjhunwala S, van Zelm MC, Peak MM, Murre C. PMID: 19665968; PMCID: PMC2726833.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    72. E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6):1930-5. Semerad CL, Mercer EM, Inlay MA, Weissman IL, Murre C. PMID: 19181846; PMCID: PMC2644141.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    73. BCR-ABL-transformed GMP as myeloid leukemic stem cells. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17967-72. Minami Y, Stuart SA, Ikawa T, Jiang Y, Banno A, Hunton IC, Young DJ, Naoe T, Murre C, Jamieson CH, Wang JY. PMID: 19004799; PMCID: PMC2582213.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    74. Suppression of E-protein activity interferes with the development of BCR-ABL-mediated myeloproliferative disease. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12967-72. Ko J, Patel N, Ikawa T, Kawamoto H, Frank O, Rivera RR, Van Etten RA, Murre C. PMID: 18725623; PMCID: PMC2529058.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    75. FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008 Jul 14; 3:17. Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL. PMID: 18625063; PMCID: PMC2492847.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    76. Nuclear geography and allelic exclusion. Nat Immunol. 2008 Jul; 9(7):718-20. Murre C. PMID: 18563080.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    77. The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell. 2008 Apr 18; 133(2):265-79. Jhunjhunwala S, van Zelm MC, Peak MM, Cutchin S, Riblet R, van Dongen JJ, Grosveld FG, Knoch TA, Murre C. PMID: 18423198; PMCID: PMC2771211.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    78. differential roles for the E2A activation domains in B lymphocytes and macrophages. J Immunol. 2008 Feb 01; 180(3):1694-703. Bhalla S, Spaulding C, Brumbaugh RL, Zagort DE, Massari ME, Murre C, Kee BL. PMID: 18209066.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    79. Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. Immunity. 2007 Dec; 27(6):871-84. Agata Y, Tamaki N, Sakamoto S, Ikawa T, Masuda K, Kawamoto H, Murre C. PMID: 18093539.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    80. Epigenetics of antigen-receptor gene assembly. Curr Opin Genet Dev. 2007 Oct; 17(5):415-21. Murre C. PMID: 17920858; PMCID: PMC2151926.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    81. Defining the pathways of early adult hematopoiesis. Cell Stem Cell. 2007 Oct 11; 1(4):357-8. Murre C. PMID: 18371371.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    82. Ribosomal proteins and the control of alphabeta T lineage development. Immunity. 2007 Jun; 26(6):751-2. Murre C. PMID: 17582347.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    83. Regulation and function of the E2A proteins in B cell development. Adv Exp Med Biol. 2007; 596:1-7. Murre C. PMID: 17338171.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    84. Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9976-81. Schwartz R, Engel I, Fallahi-Sichani M, Petrie HT, Murre C. PMID: 16782810; PMCID: PMC1502564.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    85. Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. Immunity. 2006 Jun; 24(6):813-826. Xi H, Schwartz R, Engel I, Murre C, Kersh GJ. PMID: 16782036.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    86. E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment. J Exp Med. 2006 May 15; 203(5):1329-42. Ikawa T, Kawamoto H, Goldrath AW, Murre C. PMID: 16682500; PMCID: PMC2121213.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    87. Marking emerging beta- and gammadelta-selected T cells. Immunity. 2006 Jan; 24(1):11-3. Murre C. PMID: 16413917.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    88. Pax1/E2a double-mutant mice develop non-lethal neural tube defects that resemble human malformations. Transgenic Res. 2005 Dec; 14(6):983-7. Joosten PH, van Zoelen EJ, Murre C. PMID: 16315099.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    89. Helix-loop-helix proteins and lymphocyte development. Nat Immunol. 2005 Nov; 6(11):1079-86. Murre C. PMID: 16239924.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    90. DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. Int Immunol. 2005 Nov; 17(11):1379-90. Friedrich ML, Wen BG, Bain G, Kee BL, Katayama C, Murre C, Hedrick SM, Walsh CM. PMID: 16172133.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    91. Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract. Genesis. 2005 Apr; 41(4):192-201. Vincentz JW, McWhirter JR, Murre C, Baldini A, Furuta Y. PMID: 15789410.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    92. Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev. 2005 Feb 01; 19(3):322-7. Sayegh CE, Sayegh C, Jhunjhunwala S, Riblet R, Murre C. PMID: 15687256; PMCID: PMC546510.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    93. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol. 2004 Oct; 5(10):1069-77. Maier H, Ostraat R, Gao H, Fields S, Shinton SA, Medina KL, Ikawa T, Murre C, Singh H, Hardy RR, Hagman J. PMID: 15361869.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    94. TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell. 2004 Jun; 5(6):587-96. O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. PMID: 15193261.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    95. Reprogramming committed B lineage cells. Cell. 2004 May 28; 117(5):556-8. Murre C. PMID: 15163403.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    96. Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. Dev Biol. 2004 May 01; 269(1):264-75. Wright TJ, Ladher R, McWhirter J, Murre C, Schoenwolf GC, Mansour SL. PMID: 15081372.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    97. Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A. J Exp Med. 2004 Apr 19; 199(8):1101-12. Quong MW, Martensson A, Langerak AW, Rivera RR, Nemazee D, Murre C. PMID: 15078898; PMCID: PMC2211894.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    98. Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. Immunity. 2004 Mar; 20(3):349-60. Ikawa T, Kawamoto H, Wright LY, Murre C. PMID: 15030778.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    99. E2A proteins enforce a proliferation checkpoint in developing thymocytes. EMBO J. 2004 Jan 14; 23(1):202-11. Engel I, Murre C. PMID: 14685278; PMCID: PMC1271657.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    100. Regulating intertwining proteins. Mol Cell. 2003 Nov; 12(5):1061-2. Murre C. PMID: 14636564.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    101. The cellular Pax-Hox-helix connection. Biochim Biophys Acta. 2003 Oct 01; 1629(1-3):1-7. Westerman BA, Murre C, Oudejans CB. PMID: 14522074.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    102. E-proteins directly regulate expression of activation-induced deaminase in mature B cells. Nat Immunol. 2003 Jun; 4(6):586-93. Sayegh CE, Quong MW, Agata Y, Murre C. PMID: 12717431.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    103. Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11322-7. Engel I, Murre C. PMID: 12172006; PMCID: PMC123255.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    104. IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors. EMBO J. 2002 Jan 15; 21(1-2):103-13. Kee BL, Bain G, Murre C. PMID: 11782430; PMCID: PMC125811.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    105. The function of E- and Id proteins in lymphocyte development. Nat Rev Immunol. 2001 Dec; 1(3):193-9. Engel I, Murre C. PMID: 11905828.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    106. E protein function in lymphocyte development. Annu Rev Immunol. 2002; 20:301-22. Quong MW, Romanow WJ, Murre C. PMID: 11861605.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    107. Early thymocyte development is regulated by modulation of E2A protein activity. J Exp Med. 2001 Sep 17; 194(6):733-45. Engel I, Johns C, Bain G, Rivera RR, Murre C. PMID: 11560990; PMCID: PMC2195962.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    108. The role of E2A-PBX1 in leukemogenesis. Oncogene. 2001 Sep 10; 20(40):5708-17. Aspland SE, Bendall HH, Murre C. PMID: 11607820.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    109. Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells. J Exp Med. 2001 Sep 03; 194(5):645-56. Goebel P, Janney N, Valenzuela JR, Romanow WJ, Murre C, Feeney AJ. PMID: 11535632; PMCID: PMC2195934.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    110. Transcription factor regulation of B lineage commitment. Curr Opin Immunol. 2001 Apr; 13(2):180-5. Kee BL, Murre C. PMID: 11228411.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    111. Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells. J Exp Med. 2001 Mar 19; 193(6):769-76. Ghosh JK, Romanow WJ, Murre C. PMID: 11257142; PMCID: PMC2193417.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    112. Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta. Nat Immunol. 2001 Mar; 2(3):242-7. Kee BL, Rivera RR, Murre C. PMID: 11224524.
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    113. Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nat Immunol. 2001 Feb; 2(2):165-71. Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM, Murre C. PMID: 11175815.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    114. Intertwining proteins in thymocyte development and cancer. Nat Immunol. 2000 Aug; 1(2):97-8. Murre C. PMID: 11248796.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    115. Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. Biophys J. 2000 Jun; 78(6):2878-91. Planells-Cases R, Caprini M, Zhang J, Rockenstein EM, Rivera RR, Murre C, Masliah E, Montal M. PMID: 10827969; PMCID: PMC1300874.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    116. E2A proteins: essential regulators at multiple stages of B-cell development. Immunol Rev. 2000 Jun; 175:138-49. Kee BL, Quong MW, Murre C. PMID: 10933599.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    117. E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. Mol Cell. 2000 Feb; 5(2):343-53. Romanow WJ, Langerak AW, Goebel P, Wolvers-Tettero IL, van Dongen JJ, Feeney AJ, Murre C. PMID: 10882075.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    118. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity. 2000 Jan; 12(1):17-26. Rivera RR, Johns CP, Quan J, Johnson RS, Murre C. PMID: 10661402.
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    119. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol. 2000 Jan; 20(2):429-40. Massari ME, Murre C. PMID: 10611221; PMCID: PMC85097.
      View in: PubMed   Mentions: 698     Fields:    Translation:HumansAnimalsCells
    120. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47. J Exp Med. 1999 Dec 06; 190(11):1605-16. Bain G, Quong MW, Soloff RS, Hedrick SM, Murre C. PMID: 10587351; PMCID: PMC2195738.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    121. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 1999 Nov 15; 18(22):6307-18. Quong MW, Harris DP, Swain SL, Murre C. PMID: 10562543; PMCID: PMC1171694.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    122. Transcription factors in hematopoiesis. Curr Opin Genet Dev. 1999 Oct; 9(5):575-9. Engel I, Murre C. PMID: 10508690.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    123. Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11464-9. McWhirter JR, Neuteboom ST, Wancewicz EV, Monia BP, Downing JR, Murre C. PMID: 10500199; PMCID: PMC18056.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    124. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol Cell. 1999 Jul; 4(1):63-73. Massari ME, Grant PA, Pray-Grant MG, Berger SL, Workman JL, Murre C. PMID: 10445028.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    125. Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. Proc Natl Acad Sci U S A. 1999 Feb 02; 96(3):996-1001. Engel I, Murre C. PMID: 9927682; PMCID: PMC15339.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    126. Positive and negative regulation of V(D)J recombination by the E2A proteins. J Exp Med. 1999 Jan 18; 189(2):289-300. Bain G, Romanow WJ, Albers K, Havran WL, Murre C. PMID: 9892611; PMCID: PMC2192990.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    127. Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation. EMBO J. 1999 Jan 04; 18(1):198-211. Li X, Murre C, McGinnis W. PMID: 9878063; PMCID: PMC1171115.
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    128. Role of helix-loop-helix proteins in lymphocyte development. Cold Spring Harb Symp Quant Biol. 1999; 64:39-44. Murre C. PMID: 11232313.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    129. Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12. J Exp Med. 1998 Aug 17; 188(4):699-713. Kee BL, Murre C. PMID: 9705952; PMCID: PMC2213347.
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    130. Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes. Mol Cell Biol. 1998 Jun; 18(6):3130-9. Massari ME, Rivera RR, Voland JR, Quong MW, Breit TM, van Dongen JJ, de Smit O, Murre C. PMID: 9584154; PMCID: PMC108895.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    131. The role of E-proteins in B- and T-lymphocyte development. Semin Immunol. 1998 Apr; 10(2):143-53. Bain G, Murre C. PMID: 9618760.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    132. Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA. Mol Cell Biol. 1997 Sep; 17(9):5369-76. Sánchez M, Jennings PA, Murre C. PMID: 9271414; PMCID: PMC232387.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    133. A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. Development. 1997 Sep; 124(17):3221-32. McWhirter JR, Goulding M, Weiner JA, Chun J, Murre C. PMID: 9310317.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    134. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol. 1997 Aug; 17(8):4782-91. Bain G, Engel I, Robanus Maandag EC, te Riele HP, Voland JR, Sharp LL, Chun J, Huey B, Pinkel D, Murre C. PMID: 9234734; PMCID: PMC232330.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    135. Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins. Mol Cell Biol. 1997 Aug; 17(8):4696-706. Neuteboom ST, Murre C. PMID: 9234726; PMCID: PMC232322.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    136. Specific residues in the Pbx homeodomain differentially modulate the DNA-binding activity of Hox and Engrailed proteins. Development. 1997 Mar; 124(5):1089-98. Peltenburg LT, Murre C. PMID: 9056783.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    137. Both E12 and E47 allow commitment to the B cell lineage. Immunity. 1997 Feb; 6(2):145-54. Bain G, Robanus Maandag EC, te Riele HP, Feeney AJ, Sheehy A, Schlissel M, Shinton SA, Hardy RR, Murre C. PMID: 9047236.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    138. E2A gene products are not required for insulin gene expression. Endocrinology. 1996 Aug; 137(8):3540-3. Itkin-Ansari P, Bain G, Beattie GM, Murre C, Hayek A, Levine F. PMID: 8754784.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    139. Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx. EMBO J. 1996 Jul 01; 15(13):3385-93. Peltenburg LT, Murre C. PMID: 8698039; PMCID: PMC451902.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    140. The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells. Mol Cell Biol. 1996 Jan; 16(1):121-9. Massari ME, Jennings PA, Murre C. PMID: 8524288; PMCID: PMC230985.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    141. The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9166-70. Neuteboom ST, Peltenburg LT, van Dijk MA, Murre C. PMID: 7568094; PMCID: PMC40945.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    142. Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2. Mech Dev. 1995 Jul; 52(1):99-108. van Dijk MA, Peltenburg LT, Murre C. PMID: 7577680.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    143. Localization of Pbx1 transcripts in developing rat embryos. Mech Dev. 1995 Jun; 51(2-3):193-8. Roberts VJ, van Dijk MA, Murre C. PMID: 7547467.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    144. c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products. Mol Cell Biol. 1995 Mar; 15(3):1398-404. Robinson GL, Henderson E, Massari ME, Murre C, Stein R. PMID: 7862133; PMCID: PMC230364.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    145. extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell. 1994 Aug 26; 78(4):617-24. van Dijk MA, Murre C. PMID: 7915200.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    146. Structure and function of helix-loop-helix proteins. Biochim Biophys Acta. 1994 Jun 21; 1218(2):129-35. Murre C, Bain G, van Dijk MA, Engel I, Furnari BA, Massari ME, Matthews JR, Quong MW, Rivera RR, Stuiver MH. PMID: 8018712.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    147. Ets proteins: new factors that regulate immunoglobulin heavy-chain gene expression. Mol Cell Biol. 1993 Nov; 13(11):7163-9. Rivera RR, Stuiver MH, Steenbergen R, Murre C. PMID: 8413305; PMCID: PMC364777.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    148. Localization of E2A mRNA expression in developing and adult rat tissues. Proc Natl Acad Sci U S A. 1993 Aug 15; 90(16):7583-7. Roberts VJ, Steenbergen R, Murre C. PMID: 8356060; PMCID: PMC47186.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    149. Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A. 1993 Jul 01; 90(13):6061-5. Van Dijk MA, Voorhoeve PM, Murre C. PMID: 8327485; PMCID: PMC46867.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    150. E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins. Mol Cell Biol. 1993 Jun; 13(6):3522-9. Bain G, Gruenwald S, Murre C. PMID: 8497267; PMCID: PMC359822.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    151. Dpbx, a new homeobox gene closely related to the human proto-oncogene pbx1 molecular structure and developmental expression. Mech Dev. 1993 May; 41(2-3):155-61. Flegel WA, Singson AW, Margolis JS, Bang AG, Posakony JW, Murre C. PMID: 8100142; PMCID: PMC7724736.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    152. A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells. Mol Cell Biol. 1993 Feb; 13(2):792-800. Quong MW, Massari ME, Zwart R, Murre C. PMID: 8423802; PMCID: PMC358962.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    153. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo. Cell. 1991 Jul 26; 66(2):305-15. Lassar AB, Davis RL, Wright WE, Kadesch T, Murre C, Voronova A, Baltimore D, Weintraub H. PMID: 1649701.
      View in: PubMed   Mentions: 276     Fields:    Translation:AnimalsCells
    154. B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits. Mol Cell Biol. 1991 Feb; 11(2):1156-60. Murre C, Voronova A, Baltimore D. PMID: 1990271; PMCID: PMC359799.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    155. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell. 1990 Feb 23; 60(4):547-55. Kamps MP, Murre C, Sun XH, Baltimore D. PMID: 1967983.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansCells
    156. The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias. Science. 1989 Oct 20; 246(4928):379-82. Mellentin JD, Murre C, Donlon TA, McCaw PS, Smith SD, Carroll AJ, McDonald ME, Baltimore D, Cleary ML. PMID: 2799390.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    157. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell. 1989 Aug 11; 58(3):537-44. Murre C, McCaw PS, Vaessin H, Caudy M, Jan LY, Jan YN, Cabrera CV, Buskin JN, Hauschka SD, Lassar AB, et al. PMID: 2503252.
      View in: PubMed   Mentions: 578     Fields:    Translation:AnimalsCells
    158. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 1989 Mar 10; 56(5):777-83. Murre C, McCaw PS, Baltimore D. PMID: 2493990.
      View in: PubMed   Mentions: 884     Fields:    Translation:HumansAnimalsCells
    159. AKR murine thymic leukemias are from a distinct thymic cell lineage and do not express the beta chain of the T-cell antigen receptor. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7434-7. Owen FL, Strauss WM, Murre C, Duby AD, Hiai H, Seidman JG. PMID: 3094008; PMCID: PMC386732.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    160. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. Mol Cell Biol. 1986 Sep; 6(9):3207-14. Leiden JM, Dialynas DP, Duby AD, Murre C, Seidman J, Strominger JL. PMID: 3491297; PMCID: PMC367057.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    161. Human T-cell gamma genes contain N segments and have marked junctional variability. Nature. 1986 Jul 10-16; 322(6075):184-7. Quertermous T, Strauss W, Murre C, Dialynas DP, Strominger JL, Seidman JG. PMID: 3453106.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    162. Biochemical and functional analyses of a secreted H-2Ld molecule. Mol Cell Biol. 1986 Apr; 6(4):1315-9. Murre C, Parker KC, Reiss CS, Driller JP, Wiley DC, Burakoff SJ, Seidman JG. PMID: 3491290; PMCID: PMC367644.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    163. T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. Blood. 1986 Apr; 67(4):914-8. Berliner N, Duby AD, Linch DC, Murre C, Quertermous T, Knott LJ, Azin T, Newland AC, Lewis DL, Galvin MC, et al. PMID: 3485459.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    164. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. Proc Natl Acad Sci U S A. 1986 Apr; 83(8):2619-23. Dialynas DP, Murre C, Quertermous T, Boss JM, Leiden JM, Seidman JG, Strominger JL. PMID: 3458221; PMCID: PMC323350.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    165. Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells. J Immunol. 1986 Mar 15; 136(6):2191-4. Reiss CS, Greenstein JL, Crimmins MA, Liu LL, Rao A, Maziaraz RT, Murre C, Burakoff SJ. PMID: 2419424.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    166. Human T-cell gamma chain genes: organization, diversity, and rearrangement. Science. 1986 Jan 17; 231(4735):252-5. Quertermous T, Murre C, Dialynas D, Duby AD, Strominger JL, Waldman TA, Seidman JG. PMID: 3079918.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    167. beta 2-Microglobulin from serum associates with several class I antigens expressed on the surface of mouse L-cells. Mol Immunol. 1985 Aug; 22(8):955-60. Bernabeu C, Maziarz R, Murre C, Terhorst C. PMID: 3900696.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    168. Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7. Nature. 1985 Aug 8-14; 316(6028):549-52. Murre C, Waldmann RA, Morton CC, Bongiovanni KF, Waldmann TA, Shows TB, Seidman JG. PMID: 3875797.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    169. A novel mechanism of somatic rearrangement predicted by a human T-cell antigen receptor beta-chain complementary DNA. Science. 1985 Jun 07; 228(4704):1204-6. Duby AD, Klein KA, Murre C, Seidman JG. PMID: 3839095.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    170. Polymorphism of murine major histocompatibility Class I antigen: assignment of putative allodeterminants to distinct positions of the amino acid sequence within the first external domain of the antigen. J Immunol. 1985 Mar; 134(3):1749-58. Ozato K, Takahashi H, Appella E, Sears DW, Murre C, Seidman JG, Kimura S, Tada N. PMID: 2578519.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    171. Differential expression of H-2Dd and H-2Ld histocompatibility antigens. J Exp Med. 1985 Feb 01; 161(2):356-65. Weis JH, Murre C. PMID: 3919140; PMCID: PMC2187564.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    172. An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells. Immunogenetics. 1985; 22(2):123-30. Ben-Nun A, Strauss W, Leeman SA, Cohn LE, Murre C, Duby A, Seidman JG, Glimcher LH. PMID: 3875550.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    173. Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains. J Exp Med. 1984 Jul 01; 160(1):167-78. Murre C, Choi E, Weis J, Seidman JG, Ozato K, Liu L, Burakoff SJ, Reiss CS. PMID: 6203998; PMCID: PMC2187433.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    174. Construction, expression and recognition of an H-2 molecule lacking its carboxyl terminus. Nature. 1984 Feb 2-8; 307(5950):432-6. Murre C, Reiss CS, Bernabeu C, Chen LB, Burakoff SJ, Seidman JG. PMID: 6363940.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    175. Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer. Fed Proc. 1984 Feb; 43(2):271-5. Reiss CS, Evans GA, Murre C, Margulies DH, Seidman JG, Burakoff SJ. PMID: 6198217.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    176. Correlation between two new methods for the isolation of human monocytes: specific reversible agglutination with a carbohydrate from pokeweed and by use of the lectin PA-4. Adv Exp Med Biol. 1982; 155:233-9. Waxdal MJ, Kieda C, Murre C. PMID: 7158482.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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