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Lawrence Hansen

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentPathology
Address9500 Gilman Drive #0624
La Jolla CA 92093
Phone858-534-6212
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen L, Masliah E, Gage FH. Hippocampal a-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 Feb 15; 37(7):1675-1684. PMID: 28039370.
      View in: PubMed
    2. Peavy GM, Edland SD, Toole BM, Hansen L, Galasko DR, Mayo AM. Phenotypic differences based on staging of Alzheimer's neuropathology in autopsy-confirmed dementia with Lewy bodies. Parkinsonism Relat Disord. 2016 Oct; 31:72-78. PMID: 27475955.
      View in: PubMed
    3. Mitolo M, Hamilton JM, Landy KM, Hansen L, Galasko D, Pazzaglia F, Salmon DP. Visual Perceptual Organization Ability in Autopsy-Verified Dementia with Lewy Bodies and Alzheimer's Disease. J Int Neuropsychol Soc. 2016 Jul; 22(6):609-19. PMID: 27221597.
      View in: PubMed
    4. Santiago-Dieppa DR, Zhou T, Jones KA, Gabel BC, Chen JY, Hansen L, U HS. Intracranial Rhabdomyoma: Case Report and Review of the Literature. Cureus. 2016 Apr 29; 8(4):e593. PMID: 27335706; PMCID: PMC4914064.
    5. Landy KM, Salmon DP, Galasko D, Filoteo JV, Festa EK, Heindel WC, Hansen L, Hamilton JM. Motion discrimination in dementia with Lewy bodies and Alzheimer disease. Neurology. 2015 Oct 20; 85(16):1376-82. PMID: 26400581; PMCID: PMC4626245 [Available on 10/20/16].
    6. Gabel BC, Goolsby M, Hansen L, U HS. Inflammatory Myofibroblastic Tumor of the Left Sphenoid and Cavernous Sinus Successfully Treated with Partial Resection and High Dose Radiotherapy: Case Report and Review of the Literature. Cureus. 2015 Sep 21; 7(9):e328. PMID: 26543686; PMCID: PMC4627831.
    7. Yee B, Chi NW, Hansen L, Lee RR, U HS, Savides TJ, Vinetz JM. Strongyloides stercoralis Hyperinfection Syndrome Presenting as Severe, Recurrent Gastrointestinal Bleeding, Leading to a Diagnosis of Cushing Disease. Am J Trop Med Hyg. 2015 Oct; 93(4):822-7. PMID: 26195463; PMCID: PMC4596606 [Available on 10/07/16].
    8. Salmon DP, Heindel WC, Hamilton JM, Vincent Filoteo J, Cidambi V, Hansen L, Masliah E, Galasko D. Recognition memory span in autopsy-confirmed Dementia with Lewy Bodies and Alzheimer's Disease. Neuropsychologia. 2015 Aug; 75:548-55. PMID: 26184443; PMCID: PMC4752828.
    9. Bangen KJ, Nation DA, Delano-Wood L, Weissberger GH, Hansen L, Galasko DR, Salmon DP, Bondi MW. Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease. Alzheimers Dement. 2015 Apr; 11(4):394-403.e1. PMID: 25022538; PMCID: PMC4287462.
    10. Hansen L. Animal laboratories are not needed to train medical students. J Surg Educ. 2014 Jul-Aug; 71(4):454. PMID: 24776862.
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    11. Olichney JM, Pak J, Salmon DP, Yang JC, Gahagan T, Nowacki R, Hansen L, Galasko D, Kutas M, Iragui-Madoz VJ. Abnormal P600 word repetition effect in elderly persons with preclinical Alzheimer's disease. Cogn Neurosci. 2013; 4(3-4):143-51. PMID: 24090465; PMCID: PMC3841188.
    12. Hamilton JM, Salmon DP, Raman R, Hansen L, Masliah E, Peavy GM, Galasko D. Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: beyond cognition. Alzheimers Dement. 2014 Mar; 10(2):171-8. PMID: 23850331.
      View in: PubMed
    13. Sherzai A, Edland SD, Masliah E, Hansen L, Pizzo DP, Sherzai A, Corey-Bloom J. Spongiform change in dementia with Lewy bodies and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):157-61. PMID: 22546782.
      View in: PubMed
    14. Peavy GM, Salmon DP, Edland SD, Tam S, Hansen L, Masliah E, Galasko D, Hamilton JM. Neuropsychiatric features of frontal lobe dysfunction in autopsy-confirmed patients with lewy bodies and "pure" Alzheimer disease. Am J Geriatr Psychiatry. 2013 Jun; 21(6):509-19. PMID: 23567425; PMCID: PMC3664517.
    15. Hansen L. Institution animal care and use committees need greater ethical diversity. J Med Ethics. 2013 Mar; 39(3):188-90. PMID: 23131895; PMCID: PMC3595150.
    16. Hamilton JM, Landy KM, Salmon DP, Hansen L, Masliah E, Galasko D. Early visuospatial deficits predict the occurrence of visual hallucinations in autopsy-confirmed dementia with Lewy bodies. Am J Geriatr Psychiatry. 2012 Sep; 20(9):773-81. PMID: 21997600; PMCID: PMC3260388.
    17. Greek R, Pippus A, Hansen L. The Nuremberg Code subverts human health and safety by requiring animal modeling. BMC Med Ethics. 2012 Jul 08; 13:16. PMID: 22769234; PMCID: PMC3532312.
    18. Pillai JA, Hansen L, Masliah E, Goldstein JL, Edland SD, Corey-Bloom J. Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Mov Disord. 2012 Aug; 27(9):1099-103. PMID: 22674458; PMCID: PMC3412903.
    19. Hansen L, Goodman JR, Chandna A. Analysis of Animal Research Ethics Committee Membership at American Institutions. Animals (Basel). 2012 Feb 22; 2(1):68-75. PMID: 26486777; PMCID: PMC4494267.
    20. Papanicolau-Sengos A, Wang-Rodriguez J, Wang HY, Lee RR, Wong A, Hansen L, Mahooti S, Rashidi HH. Rare case of a primary non-dural central nervous system low grade B-cell lymphoma and literature review. Int J Clin Exp Pathol. 2012; 5(1):89-95. PMID: 22295152; PMCID: PMC3267491.
    21. Nation DA, Delano-Wood L, Bangen KJ, Wierenga CE, Jak AJ, Hansen L, Galasko DR, Salmon DP, Bondi MW. Antemortem pulse pressure elevation predicts cerebrovascular disease in autopsy-confirmed Alzheimer's disease. J Alzheimers Dis. 2012; 30(3):595-603. PMID: 22451309.
      View in: PubMed
    22. Mandler M, Rockenstein E, Ubhi K, Hansen L, Adame A, Michael S, Galasko D, Santic R, Mattner F, Masliah E. Detection of peri-synaptic amyloid-ß pyroglutamate aggregates in early stages of Alzheimer's disease and in AßPP transgenic mice using a novel monoclonal antibody. J Alzheimers Dis. 2012; 28(4):783-94. PMID: 22064070; PMCID: PMC4350934.
    23. Masliah E, Hansen L. Alzheimer disease: AD pathology--emerging subtypes or age-of-onset spectrum? Nat Rev Neurol. 2011 Dec 06; 8(1):11-2. PMID: 22143361.
      View in: PubMed
    24. Ubhi K, Peng K, Lessig S, Estrella J, Adame A, Galasko D, Salmon DP, Hansen L, Kawas CH, Masliah E. Neuropathology of dementia with Lewy bodies in advanced age: a comparison with Alzheimer disease. Neurosci Lett. 2010 Nov 26; 485(3):222-7. PMID: 20849919; PMCID: PMC2987680.
    25. Crews L, Adame A, Patrick C, Delaney A, Pham E, Rockenstein E, Hansen L, Masliah E. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci. 2010 Sep 15; 30(37):12252-62. PMID: 20844121; PMCID: PMC2978735.
    26. Lessig S, Ubhi K, Galasko D, Adame A, Pham E, Remidios K, Chang M, Hansen L, Masliah E. Reduced hypocretin (orexin) levels in dementia with Lewy bodies. Neuroreport. 2010 Aug 04; 21(11):756-60. PMID: 20531237; PMCID: PMC2908368.
    27. Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E. Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins. FEBS J. 2010 Jul; 277(14):3051-67. PMID: 20573181; PMCID: PMC2933033.
    28. Crews L, Spencer B, Desplats P, Patrick C, Paulino A, Rockenstein E, Hansen L, Adame A, Galasko D, Masliah E. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy. PLoS One. 2010 Feb 19; 5(2):e9313. PMID: 20174468; PMCID: PMC2824828.
    29. Price JL, McKeel DW, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen L, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging. 2009 Jul; 30(7):1026-36. PMID: 19376612; PMCID: PMC2737680.
    30. Shaked GM, Chauv S, Ubhi K, Hansen L, Masliah E. Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease. FEBS J. 2009 May; 276(10):2736-51. PMID: 19368557; PMCID: PMC2838422.
    31. Hamilton JM, Salmon DP, Galasko D, Raman R, Emond J, Hansen L, Masliah E, Thal LJ. Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies. Neuropsychology. 2008 Nov; 22(6):729-37. PMID: 18999346; PMCID: PMC2587484.
    32. Rascovsky K, Salmon DP, Hansen L, Galasko D. Distinct cognitive profiles and rates of decline on the Mattis Dementia Rating Scale in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. J Int Neuropsychol Soc. 2008 May; 14(3):373-83. PMID: 18419836; PMCID: PMC2864090.
    33. Weisman DC, Yaari R, Hansen L, Thal LJ. Density of the brain, decline of the mind: an atypical case of Fahr disease. Arch Neurol. 2007 May; 64(5):756-7. PMID: 17502478.
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    34. Rascovsky K, Salmon DP, Hansen L, Thal LJ, Galasko D. Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. Neuropsychology. 2007 Jan; 21(1):20-30. PMID: 17201527.
      View in: PubMed
    35. Hansen L. The neuropathology of aging, mild cognitive impairment, and Alzheimer disease. Arch Neurol. 2006 May; 63(5):647-8. PMID: 16682533.
      View in: PubMed
    36. Webster B, Hansen L, Adame A, Crews L, Torrance M, Thal L, Masliah E. Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease. J Neuropathol Exp Neurol. 2006 Feb; 65(2):142-51. PMID: 16462205.
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    37. Tiraboschi P, Salmon DP, Hansen L, Hofstetter RC, Thal LJ, Corey-Bloom J. What best differentiates Lewy body from Alzheimer's disease in early-stage dementia? Brain. 2006 Mar; 129(Pt 3):729-35. PMID: 16401618.
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    38. Masliah E, Crews L, Hansen L. Synaptic remodeling during aging and in Alzheimer's disease. J Alzheimers Dis. 2006; 9(3 Suppl):91-9. PMID: 16914848.
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    39. Ho GJ, Hashimoto M, Adame A, Izu M, Alford MF, Thal LJ, Hansen L, Masliah E. Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role. Neurobiol Aging. 2005 May; 26(5):625-35. PMID: 15708437.
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    40. Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, Kordower JH, Gall C, Conner J. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med. 2005 May; 11(5):551-5. PMID: 15852017.
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    41. Langford D, Grigorian A, Hurford R, Adame A, Ellis RJ, Hansen L, Masliah E. Altered P-glycoprotein expression in AIDS patients with HIV encephalitis. J Neuropathol Exp Neurol. 2004 Oct; 63(10):1038-47. PMID: 15535131.
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    42. Hamilton JM, Salmon DP, Galasko D, Delis DC, Hansen L, Masliah E, Thomas RG, Thal LJ. A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease. J Int Neuropsychol Soc. 2004 Sep; 10(5):689-97. PMID: 15327716.
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    43. Hockett PK, Emery SC, Hansen L, Masliah E. Evidence of oxidative stress in the brains of fetuses with CNS anomalies and islet cell hyperplasia. Pediatr Dev Pathol. 2004 Jul-Aug; 7(4):370-9. PMID: 15383932.
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    44. Bannykh SI, Hansen L. Dural spread of a Merkel cell tumor. J Neurooncol. 2004 Jun; 68(2):151. PMID: 15218951.
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    45. Aryan HE, Overstreet KL, Amjadi DK, Hansen L. Primary anaplastic glio-neuronal tumor of the pineal gland: a new type of pineal neoplasm? J Clin Neurosci. 2004 Feb; 11(2):163-5. PMID: 14732376.
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    46. Davydov V, Hansen L, Shackelford DA. Is DNA repair compromised in Alzheimer's disease? Neurobiol Aging. 2003 Nov; 24(7):953-68. PMID: 12928056.
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    47. Bannykh SI, Perry A, Powell HC, Hill A, Hansen L. Malignant rhabdoid meningioma arising in the setting of preexisting ganglioglioma: a diagnosis supported by fluorescence in situ hybridization. Case report. J Neurosurg. 2002 Dec; 97(6):1450-5. PMID: 12507148.
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    48. Hansen L, Boss GR. Use of live animals in the curricula of U.S. medical schools: survey results from 2001. Acad Med. 2002 Nov; 77(11):1147-9. PMID: 12431930.
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    49. Ho GJ, Hansen L, Alford MF, Foster K, Salmon DP, Galasko D, Thal LJ, Masliah E. Age at onset is associated with disease severity in Lewy body variant and Alzheimer's disease. Neuroreport. 2002 Oct 07; 13(14):1825-8. PMID: 12395133.
      View in: PubMed
    50. Bondi MW, Serody AB, Chan AS, Eberson-Shumate SC, Delis DC, Hansen L, Salmon DP. Cognitive and neuropathologic correlates of Stroop Color-Word Test performance in Alzheimer's disease. Neuropsychology. 2002 Jul; 16(3):335-43. PMID: 12146681.
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    51. Langford TD, Letendre SL, Marcotte TD, Ellis RJ, McCutchan JA, Grant I, Mallory ME, Hansen L, Archibald S, Jernigan T, Masliah E. Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy. AIDS. 2002 May 03; 16(7):1019-29. PMID: 11953468; PMCID: PMC3548569.
    52. Hansen L, Daniel SE, Wilcock GK, Love S. Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia. J Neurol Neurosurg Psychiatry. 1998 May; 64(5):653-6. PMID: 9598683; PMCID: PMC2170082.