Lawrence Hansen

Title(s)Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. A Case of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FET) With Corticobasal Features and Language Deficits. J Neuropathol Exp Neurol. 2021 Sep 27; 80(9):890-892. Goodwill V, Coughlin D, Pizzo D, Galasko D, Hansen LA, Yuan SH, Hiniker A. PMID: 33969424.
      View in: PubMed   Mentions:    Fields:    
    2. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol. 2021 01 20; 80(2):102-111. Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunian V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF. PMID: 33367843.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    3. Cognitive decline profiles differ in Parkinson disease dementia and dementia with Lewy bodies. Neurology. 2020 05 19; 94(20):e2076-e2087. Smirnov DS, Galasko D, Edland SD, Filoteo JV, Hansen LA, Salmon DP. PMID: 32332125.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    4. Neuropsychological Deficit Profiles, Vascular Risk Factors, and Neuropathological Findings in Hispanic Older Adults with Autopsy-Confirmed Alzheimer's Disease. J Alzheimers Dis. 2019; 67(1):291-302. Weissberger GH, Gollan TH, Bondi MW, Nation DA, Hansen LA, Galasko D, Salmon DP. PMID: 30636736.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Trajectories of cognitive decline differ in hippocampal sclerosis and Alzheimer's disease. Neurobiol Aging. 2019 03; 75:169-177. Smirnov DS, Galasko D, Hansen LA, Edland SD, Brewer JB, Salmon DP. PMID: 30579145.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Clinical-Neuropathological Correlations of Alzheimer's Disease and Related Dementias in Latino Volunteers. J Alzheimers Dis. 2018; 66(4):1539-1548. Soria JA, Huisa BN, Edland SD, Litvan I, Peavy GM, Salmon DP, Hansen LA, Galasko DR, Brewer JB, González HM, Rissman RA. PMID: 30412501.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Ruptured Dural Arteriovenous Fistula/Malformation. Acad Forensic Pathol. 2017 Jun; 7(2):299-311. Snyder VS, Chen JY, Hansen LA. PMID: 31239979.
      View in: PubMed   Mentions:
    8. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 02 15; 37(7):1675-1684. Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH. PMID: 28039370.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    9. A Conceptual Overview of Axonopathy in Infants and Children with Allegedly Inflicted Head Trauma. Acad Forensic Pathol. 2016 Dec; 6(4):608-621. Snyder VS, Hansen LA. PMID: 31239934.
      View in: PubMed   Mentions:
    10. Phenotypic differences based on staging of Alzheimer's neuropathology in autopsy-confirmed dementia with Lewy bodies. Parkinsonism Relat Disord. 2016 10; 31:72-78. Peavy GM, Edland SD, Toole BM, Hansen LA, Galasko DR, Mayo AM. PMID: 27475955.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    11. Visual Perceptual Organization Ability in Autopsy-Verified Dementia with Lewy Bodies and Alzheimer's Disease. J Int Neuropsychol Soc. 2016 07; 22(6):609-19. Mitolo M, Hamilton JM, Landy KM, Hansen LA, Galasko D, Pazzaglia F, Salmon DP. PMID: 27221597.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Intracranial Rhabdomyoma: Case Report and Review of the Literature. Cureus. 2016 Apr 29; 8(4):e593. Santiago-Dieppa DR, Zhou T, Jones KA, Gabel BC, Chen JY, Hansen L, U HS. PMID: 27335706.
      View in: PubMed   Mentions: 1  
    13. Motion discrimination in dementia with Lewy bodies and Alzheimer disease. Neurology. 2015 Oct 20; 85(16):1376-82. Landy KM, Salmon DP, Galasko D, Filoteo JV, Festa EK, Heindel WC, Hansen LA, Hamilton JM. PMID: 26400581.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Inflammatory Myofibroblastic Tumor of the Left Sphenoid and Cavernous Sinus Successfully Treated with Partial Resection and High Dose Radiotherapy: Case Report and Review of the Literature. Cureus. 2015 Sep 21; 7(9):e328. Gabel BC, Goolsby M, Hansen L, U HS. PMID: 26543686.
      View in: PubMed   Mentions: 2  
    15. Strongyloides stercoralis Hyperinfection Syndrome Presenting as Severe, Recurrent Gastrointestinal Bleeding, Leading to a Diagnosis of Cushing Disease. Am J Trop Med Hyg. 2015 Oct; 93(4):822-7. Yee B, Chi NW, Hansen LA, Lee RR, U HS, Savides TJ, Vinetz JM. PMID: 26195463.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    16. Recognition memory span in autopsy-confirmed Dementia with Lewy Bodies and Alzheimer's Disease. Neuropsychologia. 2015 Aug; 75:548-55. Salmon DP, Heindel WC, Hamilton JM, Vincent Filoteo J, Cidambi V, Hansen LA, Masliah E, Galasko D. PMID: 26184443.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease. Alzheimers Dement. 2015 Apr; 11(4):394-403.e1. Bangen KJ, Nation DA, Delano-Wood L, Weissberger GH, Hansen LA, Galasko DR, Salmon DP, Bondi MW. PMID: 25022538.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    18. Animal laboratories are not needed to train medical students. J Surg Educ. 2014 Jul-Aug; 71(4):454. Hansen LA. PMID: 24776862.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    19. Abnormal P600 word repetition effect in elderly persons with preclinical Alzheimer's disease. Cogn Neurosci. 2013; 4(3-4):143-51. Olichney JM, Pak J, Salmon DP, Yang JC, Gahagan T, Nowacki R, Hansen L, Galasko D, Kutas M, Iragui-Madoz VJ. PMID: 24090465.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    20. Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: beyond cognition. Alzheimers Dement. 2014 Mar; 10(2):171-8. Hamilton JM, Salmon DP, Raman R, Hansen LA, Masliah E, Peavy GM, Galasko D. PMID: 23850331.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Spongiform change in dementia with Lewy bodies and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):157-61. Sherzai A, Edland SD, Masliah E, Hansen L, Pizzo DP, Sherzai A, Corey-Bloom J. PMID: 22546782.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Neuropsychiatric features of frontal lobe dysfunction in autopsy-confirmed patients with lewy bodies and "pure" Alzheimer disease. Am J Geriatr Psychiatry. 2013 Jun; 21(6):509-19. Peavy GM, Salmon DP, Edland SD, Tam S, Hansen LA, Masliah E, Galasko D, Hamilton JM. PMID: 23567425.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    23. Institution animal care and use committees need greater ethical diversity. J Med Ethics. 2013 Mar; 39(3):188-90. Hansen LA. PMID: 23131895.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    24. Early visuospatial deficits predict the occurrence of visual hallucinations in autopsy-confirmed dementia with Lewy bodies. Am J Geriatr Psychiatry. 2012 Sep; 20(9):773-81. Hamilton JM, Landy KM, Salmon DP, Hansen LA, Masliah E, Galasko D. PMID: 21997600.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    25. The Nuremberg Code subverts human health and safety by requiring animal modeling. BMC Med Ethics. 2012 Jul 08; 13:16. Greek R, Pippus A, Hansen LA. PMID: 22769234.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    26. Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Mov Disord. 2012 Aug; 27(9):1099-103. Pillai JA, Hansen LA, Masliah E, Goldstein JL, Edland SD, Corey-Bloom J. PMID: 22674458.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Analysis of Animal Research Ethics Committee Membership at American Institutions. Animals (Basel). 2012 Feb 22; 2(1):68-75. Hansen LA, Goodman JR, Chandna A. PMID: 26486777.
      View in: PubMed   Mentions: 7  
    28. Rare case of a primary non-dural central nervous system low grade B-cell lymphoma and literature review. Int J Clin Exp Pathol. 2012; 5(1):89-95. Papanicolau-Sengos A, Wang-Rodriguez J, Wang HY, Lee RR, Wong A, Hansen LA, Mahooti S, Rashidi HH. PMID: 22295152.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Antemortem pulse pressure elevation predicts cerebrovascular disease in autopsy-confirmed Alzheimer's disease. J Alzheimers Dis. 2012; 30(3):595-603. Nation DA, Delano-Wood L, Bangen KJ, Wierenga CE, Jak AJ, Hansen LA, Galasko DR, Salmon DP, Bondi MW. PMID: 22451309.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    30. Detection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibody. J Alzheimers Dis. 2012; 28(4):783-94. Mandler M, Rockenstein E, Ubhi K, Hansen L, Adame A, Michael S, Galasko D, Santic R, Mattner F, Masliah E. PMID: 22064070.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    31. Alzheimer disease: AD pathology--emerging subtypes or age-of-onset spectrum? Nat Rev Neurol. 2011 Dec 06; 8(1):11-2. Masliah E, Hansen LA. PMID: 22143361.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Neuropathology of dementia with Lewy bodies in advanced age: a comparison with Alzheimer disease. Neurosci Lett. 2010 Nov 26; 485(3):222-7. Ubhi K, Peng K, Lessig S, Estrella J, Adame A, Galasko D, Salmon DP, Hansen LA, Kawas CH, Masliah E. PMID: 20849919.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    33. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci. 2010 Sep 15; 30(37):12252-62. Crews L, Adame A, Patrick C, Delaney A, Pham E, Rockenstein E, Hansen L, Masliah E. PMID: 20844121.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    34. Reduced hypocretin (orexin) levels in dementia with Lewy bodies. Neuroreport. 2010 Aug 04; 21(11):756-60. Lessig S, Ubhi K, Galasko D, Adame A, Pham E, Remidios K, Chang M, Hansen LA, Masliah E. PMID: 20531237.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    35. Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins. FEBS J. 2010 Jul; 277(14):3051-67. Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E. PMID: 20573181.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    36. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy. PLoS One. 2010 Feb 19; 5(2):e9313. Crews L, Spencer B, Desplats P, Patrick C, Paulino A, Rockenstein E, Hansen L, Adame A, Galasko D, Masliah E. PMID: 20174468.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansAnimalsCells
    37. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging. 2009 Jul; 30(7):1026-36. Price JL, McKeel DW, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. PMID: 19376612.
      View in: PubMed   Mentions: 296     Fields:    Translation:HumansCells
    38. Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease. FEBS J. 2009 May; 276(10):2736-51. Shaked GM, Chauv S, Ubhi K, Hansen LA, Masliah E. PMID: 19368557.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies. Neuropsychology. 2008 Nov; 22(6):729-37. Hamilton JM, Salmon DP, Galasko D, Raman R, Emond J, Hansen LA, Masliah E, Thal LJ. PMID: 18999346.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    40. Distinct cognitive profiles and rates of decline on the Mattis Dementia Rating Scale in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. J Int Neuropsychol Soc. 2008 May; 14(3):373-83. Rascovsky K, Salmon DP, Hansen LA, Galasko D. PMID: 18419836.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    41. Density of the brain, decline of the mind: an atypical case of Fahr disease. Arch Neurol. 2007 May; 64(5):756-7. Weisman DC, Yaari R, Hansen LA, Thal LJ. PMID: 17502478.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. Neuropsychology. 2007 Jan; 21(1):20-30. Rascovsky K, Salmon DP, Hansen LA, Thal LJ, Galasko D. PMID: 17201527.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    43. The neuropathology of aging, mild cognitive impairment, and Alzheimer disease. Arch Neurol. 2006 May; 63(5):647-8. Hansen LA. PMID: 16682533.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease. J Neuropathol Exp Neurol. 2006 Feb; 65(2):142-51. Webster B, Hansen L, Adame A, Crews L, Torrance M, Thal L, Masliah E. PMID: 16462205.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    45. What best differentiates Lewy body from Alzheimer's disease in early-stage dementia? Brain. 2006 Mar; 129(Pt 3):729-35. Tiraboschi P, Salmon DP, Hansen LA, Hofstetter RC, Thal LJ, Corey-Bloom J. PMID: 16401618.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    46. Synaptic remodeling during aging and in Alzheimer's disease. J Alzheimers Dis. 2006; 9(3 Suppl):91-9. Masliah E, Crews L, Hansen L. PMID: 16914848.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    47. Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role. Neurobiol Aging. 2005 May; 26(5):625-35. Ho GJ, Hashimoto M, Adame A, Izu M, Alford MF, Thal LJ, Hansen LA, Masliah E. PMID: 15708437.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    48. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med. 2005 May; 11(5):551-5. Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, Kordower JH, Gall C, Conner J. PMID: 15852017.
      View in: PubMed   Mentions: 273     Fields:    Translation:HumansCellsCTClinical Trials
    49. Altered P-glycoprotein expression in AIDS patients with HIV encephalitis. J Neuropathol Exp Neurol. 2004 Oct; 63(10):1038-47. Langford D, Grigorian A, Hurford R, Adame A, Ellis RJ, Hansen L, Masliah E. PMID: 15535131.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    50. A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease. J Int Neuropsychol Soc. 2004 Sep; 10(5):689-97. Hamilton JM, Salmon DP, Galasko D, Delis DC, Hansen LA, Masliah E, Thomas RG, Thal LJ. PMID: 15327716.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    51. Evidence of oxidative stress in the brains of fetuses with CNS anomalies and islet cell hyperplasia. Pediatr Dev Pathol. 2004 Jul-Aug; 7(4):370-9. Hockett PK, Emery SC, Hansen L, Masliah E. PMID: 15383932.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. Dural spread of a Merkel cell tumor. J Neurooncol. 2004 Jun; 68(2):151. Bannykh SI, Hansen L. PMID: 15218951.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. Primary anaplastic glio-neuronal tumor of the pineal gland: a new type of pineal neoplasm? J Clin Neurosci. 2004 Feb; 11(2):163-5. Aryan HE, Overstreet KL, Amjadi DK, Hansen LA. PMID: 14732376.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Is DNA repair compromised in Alzheimer's disease? Neurobiol Aging. 2003 Nov; 24(7):953-68. Davydov V, Hansen LA, Shackelford DA. PMID: 12928056.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    55. Malignant rhabdoid meningioma arising in the setting of preexisting ganglioglioma: a diagnosis supported by fluorescence in situ hybridization. Case report. J Neurosurg. 2002 Dec; 97(6):1450-5. Bannykh SI, Perry A, Powell HC, Hill A, Hansen LA. PMID: 12507148.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    56. Use of live animals in the curricula of U.S. medical schools: survey results from 2001. Acad Med. 2002 Nov; 77(11):1147-9. Hansen LA, Boss GR. PMID: 12431930.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    57. Age at onset is associated with disease severity in Lewy body variant and Alzheimer's disease. Neuroreport. 2002 Oct 07; 13(14):1825-8. Ho GJ, Hansen LA, Alford MF, Foster K, Salmon DP, Galasko D, Thal LJ, Masliah E. PMID: 12395133.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    58. Cognitive and neuropathologic correlates of Stroop Color-Word Test performance in Alzheimer's disease. Neuropsychology. 2002 Jul; 16(3):335-43. Bondi MW, Serody AB, Chan AS, Eberson-Shumate SC, Delis DC, Hansen LA, Salmon DP. PMID: 12146681.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    59. Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy. AIDS. 2002 May 03; 16(7):1019-29. Langford TD, Letendre SL, Marcotte TD, Ellis RJ, McCutchan JA, Grant I, Mallory ME, Hansen LA, Archibald S, Jernigan T, Masliah E, HNRC Group . PMID: 11953468.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    60. Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia. J Neurol Neurosurg Psychiatry. 1998 May; 64(5):653-6. Hansen LA, Daniel SE, Wilcock GK, Love S. PMID: 9598683.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
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