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    Mark Geyer

    TitleRecall Faculty
    SchoolUniversity of California, San Diego
    DepartmentPsychiatry
    Address9500 Gilman Drive #0804
    CA La Jolla 92093
    Phone619-543-3582
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      Collapse Overview

      Biography

      Mark A. Geyer Ph.D. is the former Vice Chair for Research in Psychiatry and directs the Neuropsychopharmacology Unit of the VISN 22 VA’s Mental Illness Research, Clinical, and Education Center. He was involved intensively in the NIMH-funded MATRICS, TURNS, and CNTRICS Programs. Dr. Geyer is a pioneer in the translational study of sensorimotor gating deficits in schizophrenia and related animal models and has published over 425 peer-reviewed papers and many reviews, chapters, and edited books. He is the lead Series Editor for Current Topics in Behavioral Neurosciences, which has completed 16 volumes. His research program has been supported continuously by grants from NIMH and NIDA for 30+ years. He is Associate Editor of Neuropsychopharmacology, Fellow and Council Member of the ACNP, Fellow of AAAS and American Psychological Society, Past-President of the Serotonin Club, Past-President and Fellow of International Behavioral Neuroscience Society, member of Scientific Council of NARSAD, Scientific Advisor to European Union’s Innovative Medicine Initiative, and 2011 awardee of Bleuler Prize for Research in the Schizophrenias.

      Research Interests

      Dr. Geyer’s research group focuses on developing parallel behavioral paradigms in animals and humans for use in psychiatric drug discovery. For example, working with Dr. David Braff, Dr. Geyer published the first study demonstrating that prepulse inhibition (PPI) of startle, a measure of sensorimotor gating, is disrupted in schizophrenic patients in 1978. Since then, research in his laboratory has shown that PPI in animals is disrupted by a number of agents that are psychoactive in humans and in a number of lines of mutant mice. These findings led to the acceptance of PPI as an animal model related to schizophrenia and bipolar mania that reflects aspects of the disease states observed in patients. His translational group currently includes five faculty members, Drs. Susan Powell, Victoria Risbrough, Xianjin Zhou, Jared Young, and Adam Halberstadt. Our combined laboratories use behavioral measures and psychopharmacological manipulations in rodents and humans to examine the roles of neurotransmitters in behavior, to develop animal models of human drug effects, and to explore information-processing deficits in psychiatric disorders. We use startle measures of habituation, prepulse inhibition, anxiety potentiation, and fear extinction that are deficient in psychiatric disorders and can be mimicked in rodents by pharmacological, developmental, and genetic manipulations. Under Dr. Risbrough’s leadership, the group is using a battery of startle tests in a prospective longitudinal Marine Resilience Study, paralleled by neurobiological studies of CRF systems and stressors in rodents. Dr. Geyer has developed a Behavioral Pattern Monitor for use in rats, mice, and humans. These systems provide cross-species translational and multivariate assessments of spatio-temporal patterns of exploratory behavior and are being used in comparisons of schizophrenia and bipolar mania in relationship to corresponding animal models and the effects of psychostimulants in human volunteers. We have explored the effects of classical hallucinogens, dopaminergic psychostimulants, and both direct and indirect serotonin agonists to elucidate their respective mechanisms of action and to reveal the involvement of specific monoamine systems and receptors in behavioral responses to environmental stimuli and in processes such as arousal, habituation, and sensorimotor gating. Animal models of interest in the laboratory include pharmacological manipulations, a variety of developmental perturbations, and genetic models involving strain comparisons, knockouts, and humanized mutant mice, most of which are related to psychotic and/or stress-related disorders. A current focus of the laboratory is the development of murine tests of specific cognitive domains relevant to the MATRICS and CNTRICS efforts to treat cognitive deficits in psychiatric disorders.


      Collapse Research 
      Collapse Research Activities and Funding
      Early postnatal disruptions to glutamate and GABA systems and their contribution to reward deficits
      NIH/NIMH R01MH108653Jul 15, 2016 - Apr 30, 2021
      Role: Principal Investigator
      Serotonin Club IUPHAR Satellite Meeting
      NIH/NIMH R13MH078663Jul 1, 2006 - Jun 30, 2007
      Role: Principal Investigator
      Stress and CRF System Effects on Information Processing
      NIH/NIMH R01MH074697Jul 1, 2005 - Apr 30, 2015
      Role: Principal Investigator
      Sp4 Pathway in the Modulation of Sensorimotor Gating and Memory
      NIH/NIMH R01MH073991Dec 1, 2004 - Jul 31, 2015
      Role: Principal Investigator
      INHIBITORY DEFICITS IN HUMAN AND ANIMAL MODELS OF BIPOLAR DISORDER
      NIH/NIMH R01MH071916Aug 25, 2004 - Apr 30, 2015
      Role: Principal Investigator
      STARTLE GATING AND LOCOMOTION IN D2-FAMILY KNOCKOUT MICE
      NIH/NIMH R01MH061326Jun 1, 2000 - May 31, 2006
      Role: Principal Investigator
      Developmental Models of Gating Deficits in Schizophrenia
      NIH/NIMH R01MH052885Apr 1, 1995 - Apr 30, 2012
      Role: Principal Investigator
      LIMBIC MONOAMINES, BEHAVIOR, AND PSYCHOPATHOLOGY
      NIH/NIMH K05MH001223Sep 30, 1994 - Dec 31, 1999
      Role: Principal Investigator
      PREPULSE INHIBITION IN RATS REARED IN ISOLATION
      NIH/FIC F06TW001813Aug 4, 1993
      Role: Principal Investigator
      DRUGS OF ABUSE--COMPLEXITY MEASURES CLASSIFY BEHAVIOR
      NIH/NIDA R01DA006325Mar 1, 1990 - Feb 28, 1995
      Role: Principal Investigator
      LIMBIC MONOAMINES, BEHAVIOR, &PSYCHOPATHOLOGY
      NIH/NIMH K02MH000188Sep 1, 1983 - Aug 31, 1994
      Role: Principal Investigator
      HIPPOCAMPAL TRANSMITTER EFFICACY AFTER ANTIDEPRESSANTS
      NIH/NIMH R01MH037954Sep 1, 1983 - Mar 31, 1989
      Role: Principal Investigator
      Monoamine and Hallucinogen Effects on Rodent Behavior
      NIH/NIDA R01DA002925Sep 30, 1981 - Jan 31, 2016
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Deslauriers J, Acheson DT, Maihofer AX, Nievergelt CM, Baker DG, Geyer M, Risbrough VB. COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma. Depress Anxiety. 2017 Aug 18. PMID: 28833952.
        View in: PubMed
      2. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer M, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 Aug 02; 8:16140. PMID: 28767105.
        View in: PubMed
      3. Cope ZA, Minassian A, Kreitner D, MacQueen DA, Milienne-Petiot M, Geyer M, Perry W, Young JW. Modafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species. Neuropharmacology. 2017 Oct; 125:254-262. PMID: 28774856.
        View in: PubMed
      4. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer M, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 Jun 14; 8:15805. PMID: 28613276.
        View in: PubMed
      5. Glenn DE, Acheson DT, Geyer M, Nievergelt CM, Baker DG, Risbrough VB. Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms. Depress Anxiety. 2017 Aug; 34(8):723-733. PMID: 28489272.
        View in: PubMed
      6. Higa KK, Grim A, Kamenski ME, van Enkhuizen J, Zhou X, Li K, Naviaux JC, Wang L, Naviaux RK, Geyer M, Markou A, Young JW. Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice. Psychopharmacology (Berl). 2017 May; 234(9-10):1573-1586. PMID: 28243714.
        View in: PubMed
      7. Halberstadt AL, Geyer M. Effect of Hallucinogens on Unconditioned Behavior. Curr Top Behav Neurosci. 2017 Feb 22. PMID: 28224459.
        View in: PubMed
      8. Milienne-Petiot M, Geyer M, Arnt J, Young JW. Brexpiprazole reduces hyperactivity, impulsivity, and risk-preference behavior in mice with dopamine transporter knockdown-a model of mania. Psychopharmacology (Berl). 2017 Mar; 234(6):1017-1028. PMID: 28160035.
        View in: PubMed
      9. Deslauriers J, van Wijngaarde M, Geyer M, Powell S, Risbrough VB. Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice. Behav Brain Res. 2017 Apr 14; 323:117-123. PMID: 28159589.
        View in: PubMed
      10. Higa KK, Young JW, Ji B, Nichols DE, Geyer M, Zhou X. Striatal dopamine D1 receptor suppression impairs reward-associative learning. Behav Brain Res. 2017 Apr 14; 323:100-110. PMID: 28143767.
        View in: PubMed
      11. Geyer M. Athina Markou. Neuropsychopharmacology. 2016 Dec; 41(13):3121-3122. PMID: 27818512.
        View in: PubMed
      12. Ahmari SE, Risbrough VB, Geyer M, Simpson HB. Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females. Neuropsychopharmacology. 2016 Dec; 41(13):2963-2964. PMID: 27818517.
        View in: PubMed
      13. Milienne-Petiot M, Kesby JP, Graves M, van Enkhuizen J, Semenova S, Minassian A, Markou A, Geyer M, Young JW. The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania. Neuropharmacology. 2017 Feb; 113(Pt A):260-270. PMID: 27732870.
        View in: PubMed
      14. Swerdlow NR, Braff DL, Geyer M. Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next. J Psychopharmacol. 2016 Nov; 30(11):1072-1081. PMID: 27539931.
        View in: PubMed
      15. Cope ZA, Halberstadt AL, van Enkhuizen J, Flynn AD, Breier M, Swerdlow NR, Geyer M, Young JW. Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges. Psychopharmacology (Berl). 2016 Oct; 233(19-20):3513-25. PMID: 27534540; PMCID: PMC5023490 [Available on 10/01/17].
      16. Bespalov A, Steckler T, Altevogt B, Koustova E, Skolnick P, Deaver D, Millan MJ, Bastlund JF, Doller D, Witkin J, Moser P, O'Donnell P, Ebert U, Geyer M, Prinssen E, Ballard T, Macleod M. Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets. Nat Rev Drug Discov. 2016 Jul; 15(7):516. PMID: 27312728.
        View in: PubMed
      17. Halberstadt AL, Sindhunata IS, Scheffers K, Flynn AD, Sharp RF, Geyer M, Young JW. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. 2016 Aug; 107:364-375. PMID: 27020041.
        View in: PubMed
      18. Steinman SA, Ahmari SE, Choo T, Kimeldorf MB, Feit R, Loh S, Risbrough V, Geyer M, Steinglass JE, Wall M, Schneier FR, Fyer AJ, Simpson HB. PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER. Depress Anxiety. 2016 Mar; 33(3):238-46. PMID: 26878422; PMCID: PMC4806386 [Available on 03/01/17].
      19. Glenn DE, Acheson DT, Geyer M, Nievergelt CM, Baker DG, Risbrough VB. HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES. Depress Anxiety. 2016 Mar; 33(3):192-202. PMID: 26878585.
        View in: PubMed
      20. Higa KK, Young JW, Geyer M. Wet or dry: translatable "water mazes" for mice and humans. J Clin Invest. 2016 Feb; 126(2):477-9. PMID: 26784538; PMCID: PMC4731183 [Available on 02/01/17].
      21. Young JW, Minassian A, Geyer M. Locomotor Profiling from Rodents to the Clinic and Back Again. Curr Top Behav Neurosci. 2016; 28:287-303. PMID: 27418071.
        View in: PubMed
      22. Yurgil KA, Clifford RE, Risbrough VB, Geyer M, Huang M, Barkauskas DA, Vasterling JJ, Baker DG. Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines. J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9. PMID: 25699623.
        View in: PubMed
      23. Toth M, Flandreau EI, Deslauriers J, Geyer M, Mansuy IM, Merlo Pich E, Risbrough VB. Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood. Neuropsychopharmacology. 2016 May; 41(6):1681-90. PMID: 26538448; PMCID: PMC4832031 [Available on 05/01/17].
      24. Geyer M. Lysergic Acid Diethylamide and Psilocybin Revisited. Biol Psychiatry. 2015 Oct 15; 78(8):516-8. PMID: 26386624.
        View in: PubMed
      25. Minassian A, Young JW, Cope ZA, Henry BL, Geyer M, Perry W. Amphetamine increases activity but not exploration in humans and mice. Psychopharmacology (Berl). 2016 Jan; 233(2):225-33. PMID: 26449721; PMCID: PMC4703551 [Available on 01/01/17].
      26. Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer M, Risbrough VB. Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 2015 Oct; 72(10):979-86. PMID: 26353072.
        View in: PubMed
      27. van Enkhuizen J, Geyer M, Minassian A, Perry W, Henry BL, Young JW. Investigating the underlying mechanisms of aberrant behaviors in bipolar disorder from patients to models: Rodent and human studies. Neurosci Biobehav Rev. 2015 Nov; 58:4-18. PMID: 26297513; PMCID: PMC4684462 [Available on 11/01/16].
      28. van Enkhuizen J, Milienne-Petiot M, Geyer M, Young JW. Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features. Psychopharmacology (Berl). 2015 Sep; 232(18):3455-67. PMID: 26141192; PMCID: PMC4537820.
      29. Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer M, Zhou X. Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063. PMID: 26037489; PMCID: PMC4756721.
      30. Powell SB, Khan A, Young JW, Scott CN, Buell MR, Caldwell S, Tsan E, de Jong LA, Acheson DT, Lucero J, Geyer M, Behrens MM. Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. Dev Neurosci. 2015; 37(3):253-62. PMID: 26022788; PMCID: PMC4644772.
      31. Young JW, Kamenski ME, Higa KK, Light GA, Geyer M, Zhou X. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology. 2015 Nov; 40(12):2715-26. PMID: 25907107; PMCID: PMC4864647 [Available on 11/01/16].
      32. Young JW, Geyer M. Developing treatments for cognitive deficits in schizophrenia: the challenge of translation. J Psychopharmacol. 2015 Feb; 29(2):178-96. PMID: 25516372; PMCID: PMC4670265.
      33. Flandreau E, Risbrough V, Lu A, Ableitner M, Geyer M, Holsboer F, Deussing JM. Cell type-specific modifications of corticotropin-releasing factor (CRF) and its type 1 receptor (CRF1) on startle behavior and sensorimotor gating. Psychoneuroendocrinology. 2015 Mar; 53:16-28. PMID: 25575243; PMCID: PMC4364548.
      34. Acheson DT, Geyer M, Baker DG, Nievergelt CM, Yurgil K, Risbrough VB. Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines. Psychoneuroendocrinology. 2015 Jan; 51:495-505. PMID: 25444643; PMCID: PMC4345165.
      35. van Enkhuizen J, Janowsky DS, Olivier B, Minassian A, Perry W, Young JW, Geyer M. The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited. Eur J Pharmacol. 2015 Apr 15; 753:114-26. PMID: 25107282; PMCID: PMC4318788.
      36. van Enkhuizen J, Henry BL, Minassian A, Perry W, Milienne-Petiot M, Higa KK, Geyer M, Young JW. Reduced dopamine transporter functioning induces high-reward risk-preference consistent with bipolar disorder. Neuropsychopharmacology. 2014 Dec; 39(13):3112-22. PMID: 25005251; PMCID: PMC4229584.
      37. Ji B, Higa KK, Kim M, Zhou L, Young JW, Geyer M, Zhou X. Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders. Hum Mol Genet. 2014 Nov 01; 23(21):5683-705. PMID: 24908665; PMCID: PMC4189903.
      38. Csomor PA, Preller KH, Geyer M, Studerus E, Huber T, Vollenweider FX. Influence of aripiprazole, risperidone, and amisulpride on sensory and sensorimotor gating in healthy 'low and high gating' humans and relation to psychometry. Neuropsychopharmacology. 2014 Sep; 39(10):2485-96. PMID: 24801767; PMCID: PMC4138738.
      39. Minassian A, Geyer M, Baker DG, Nievergelt CM, O'Connor DT, Risbrough VB. Heart rate variability characteristics in a large group of active-duty marines and relationship to posttraumatic stress. Psychosom Med. 2014 May; 76(4):292-301. PMID: 24804881; PMCID: PMC4062545.
      40. Young JW, Ratty A, Dawe GS, Geyer M. Altered exploration and sensorimotor gating of the chakragati mouse model of schizophrenia. Behav Neurosci. 2014 Aug; 128(4):460-7. PMID: 24708299; PMCID: PMC4107138.
      41. Amitai N, Young JW, Higa K, Sharp RF, Geyer M, Powell SB. Isolation rearing effects on probabilistic learning and cognitive flexibility in rats. Cogn Affect Behav Neurosci. 2014 Mar; 14(1):388-406. PMID: 23943516; PMCID: PMC3923850.
      42. Patt VM, Thomas ML, Minassian A, Geyer M, Brown GG, Perry W. Disentangling working memory processes during spatial span assessment: a modeling analysis of preferred eye movement strategies. J Clin Exp Neuropsychol. 2014; 36(2):186-204. PMID: 24499103; PMCID: PMC3970432.
      43. Henry BL, Geyer M, Buell MR, Perry W, Young JW, Minassian A. Prepulse inhibition in HIV-1 gp120 transgenic mice after withdrawal from chronic methamphetamine. Behav Pharmacol. 2014 Feb; 25(1):12-22. PMID: 24281153; PMCID: PMC3926694.
      44. Acheson DT, Geyer M, Risbrough VB. Psychophysiology in the study of psychological trauma: where are we now and where do we need to be? Curr Top Behav Neurosci. 2014; 21:157-83. PMID: 25158622.
        View in: PubMed
      45. van Enkhuizen J, Acheson D, Risbrough V, Drummond S, Geyer M, Young JW. Sleep deprivation impairs performance in the 5-choice continuous performance test: similarities between humans and mice. Behav Brain Res. 2014 Mar 15; 261:40-8. PMID: 24333377; PMCID: PMC3937379.
      46. Toth M, Gresack JE, Bangasser DA, Plona Z, Valentino RJ, Flandreau EI, Mansuy IM, Merlo-Pich E, Geyer M, Risbrough VB. Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice. Neuropsychopharmacology. 2014 May; 39(6):1409-19. PMID: 24326400; PMCID: PMC3988544.
      47. van Enkhuizen J, Geyer M, Halberstadt AL, Zhuang X, Young JW. Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder. J Affect Disord. 2014 Feb; 155:247-54. PMID: 24287168; PMCID: PMC3924859.
      48. Young JW, Geyer M, Rissling AJ, Sharp RF, Eyler LT, Asgaard GL, Light GA. Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice. Transl Psychiatry. 2013 Nov 12; 3:e324. PMID: 24217494; PMCID: PMC3849961.
      49. Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer M, Greenberg JH, Halgren E, Hämäläinen MS, Helmchen F, Hyman BT, Jasanoff A, Jernigan TL, Judd LL, Kim SG, Kleinfeld D, Kopell NJ, Kutas M, Kwong KK, Larkum ME, Lo EH, Magistretti PJ, Mandeville JB, Masliah E, Mitra PP, Mobley WC, Moskowitz MA, Nimmerjahn A, Reynolds JH, Rosen BR, Salzberg BM, Schaffer CB, Silva GA, So PT, Spitzer NC, Tootell RB, Van Essen DC, Vanduffel W, Vinogradov SA, Wald LL, Wang LV, Weber B, Yodh AG. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 2013 Oct 16; 80(2):270-4. PMID: 24139032; PMCID: PMC3864648.
      50. Moore H, Geyer M, Carter CS, Barch DM. Harnessing cognitive neuroscience to develop new treatments for improving cognition in schizophrenia: CNTRICS selected cognitive paradigms for animal models. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2087-91. PMID: 24090823; PMCID: PMC3965347.
      51. Dean B, Moller HJ, Svensson TH, Geyer M, Rujescu D, Scarr E, Millan MJ. Problems and solutions to filling the drying drug pipeline for psychiatric disorders: a report from the inaugural 2012 CINP Think Tank. Int J Neuropsychopharmacol. 2014 Jan; 17(1):137-48. PMID: 24063634.
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      52. Halberstadt AL, Geyer M. Effects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response. Neuropharmacology. 2014 Feb; 77:200-7. PMID: 24012658; PMCID: PMC3866097.
      53. Halberstadt AL, Geyer M. Serotonergic hallucinogens as translational models relevant to schizophrenia. Int J Neuropsychopharmacol. 2013 Nov; 16(10):2165-80. PMID: 23942028; PMCID: PMC3928979.
      54. Siegel SJ, Talpos JC, Geyer M. Animal models and measures of perceptual processing in schizophrenia. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2092-8. PMID: 23867801; PMCID: PMC3849201.
      55. Young JW, Geyer M. Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia. Biochem Pharmacol. 2013 Oct 15; 86(8):1122-32. PMID: 23856289; PMCID: PMC3797190.
      56. Ji B, Wang X, Pinto-Duarte A, Kim M, Caldwell S, Young JW, Behrens MM, Sejnowski TJ, Geyer M, Zhou X. Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia. PLoS One. 2013; 8(6):e66327. PMID: 23823008; PMCID: PMC3688895.
      57. Henry BL, Minassian A, Patt VM, Hua J, Young JW, Geyer M, Perry W. Inhibitory deficits in euthymic bipolar disorder patients assessed in the human behavioral pattern monitor. J Affect Disord. 2013 Sep 25; 150(3):948-54. PMID: 23759280; PMCID: PMC3759601.
      58. Minassian A, Henry BL, Woods SP, Vaida F, Grant I, Geyer M, Perry W. Prepulse inhibition in HIV-associated neurocognitive disorders. J Int Neuropsychol Soc. 2013 Jul; 19(6):709-17. PMID: 23552464; PMCID: PMC3729041.
      59. Liu X, Hong SI, Park SJ, Dela Peña JB, Che H, Yoon SY, Kim DH, Kim JM, Cai M, Risbrough V, Geyer M, Shin CY, Cheong JH, Park H, Lew JH, Ryu JH. The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice. Arch Pharm Res. 2013 Jul; 36(7):854-63. PMID: 23543630.
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      60. Halberstadt AL, Geyer M. Characterization of the head-twitch response induced by hallucinogens in mice: detection of the behavior based on the dynamics of head movement. Psychopharmacology (Berl). 2013 Jun; 227(4):727-39. PMID: 23407781; PMCID: PMC3866102.
      61. Halberstadt AL, Powell SB, Geyer M. Role of the 5-HT2A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice. Neuropharmacology. 2013 Jul; 70:218-27. PMID: 23376711; PMCID: PMC3934507.
      62. Young JW, Meves JM, Geyer M. Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test. Behav Brain Res. 2013 Mar 01; 240:119-33. PMID: 23201359; PMCID: PMC3538919.
      63. van Enkhuizen J, Geyer M, Kooistra K, Young JW. Chronic valproate attenuates some, but not all, facets of mania-like behaviour in mice. Int J Neuropsychopharmacol. 2013 Jun; 16(5):1021-31. PMID: 23164454; PMCID: PMC3920978.
      64. Holstein DH, Vollenweider FX, Geyer M, Csomor PA, Belser N, Eich D. Sensory and sensorimotor gating in adult attention-deficit/hyperactivity disorder (ADHD). Psychiatry Res. 2013 Jan 30; 205(1-2):117-26. PMID: 23017654.
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      65. van Enkhuizen J, Geyer M, Young JW. Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task: relevance to mania. Psychopharmacology (Berl). 2013 Feb; 225(3):661-74. PMID: 22945515; PMCID: PMC3537839.
      66. Henry BL, Geyer M, Buell M, Perry W, Young JW, Minassian A. Behavioral effects of chronic methamphetamine treatment in HIV-1 gp120 transgenic mice. Behav Brain Res. 2013 Jan 01; 236(1):210-20. PMID: 22960458; PMCID: PMC3482284.
      67. Geyer M, Olivier B, Joëls M, Kahn RS. From antipsychotic to anti-schizophrenia drugs: role of animal models. Trends Pharmacol Sci. 2012 Oct; 33(10):515-21. PMID: 22810174; PMCID: PMC3461097.
      68. Light GA, Swerdlow NR, Rissling AJ, Radant A, Sugar CA, Sprock J, Pela M, Geyer M, Braff DL. Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia. PLoS One. 2012; 7(7):e39434. PMID: 22802938; PMCID: PMC3389010.
      69. Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, Salomon D, Schork NJ, Fanous AH, O'Donovan MC, Niculescu AB. Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Mol Psychiatry. 2012 Sep; 17(9):887-905. PMID: 22584867; PMCID: PMC3427857.
      70. Baker DG, Nash WP, Litz BT, Geyer M, Risbrough VB, Nievergelt CM, O'Connor DT, Larson GE, Schork NJ, Vasterling JJ, Hammer PS, Webb-Murphy JA. Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study. Prev Chronic Dis. 2012; 9:E97. PMID: 22575082; PMCID: PMC3431952.
      71. Swerdlow NR, Light GA, Breier MR, Shoemaker JM, Saint Marie RL, Neary AC, Geyer M, Stevens KE, Powell SB. Sensory and sensorimotor gating deficits after neonatal ventral hippocampal lesions in rats. Dev Neurosci. 2012; 34(2-3):240-9. PMID: 22572564.
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      72. Tanaka S, Young JW, Halberstadt AL, Masten VL, Geyer M. Four factors underlying mouse behavior in an open field. Behav Brain Res. 2012 Jul 15; 233(1):55-61. PMID: 22569582; PMCID: PMC3866095.
      73. Acheson DT, Stein MB, Paulus MP, Geyer M, Risbrough VB. The effect of pregabalin on sensorimotor gating in 'low' gating humans and mice. Neuropharmacology. 2012 Sep; 63(3):480-5. PMID: 22575075; PMCID: PMC3572212.
      74. Halberstadt AL, Buell MR, Price DL, Geyer M. Differences in the locomotor-activating effects of indirect serotonin agonists in habituated and non-habituated rats. Pharmacol Biochem Behav. 2012 Jul; 102(1):88-94. PMID: 22487771; PMCID: PMC3354037.
      75. Millan MJ, Agid Y, Brüne M, Bullmore ET, Carter CS, Clayton NS, Connor R, Davis S, Deakin B, DeRubeis RJ, Dubois B, Geyer M, Goodwin GM, Gorwood P, Jay TM, Joëls M, Mansuy IM, Meyer-Lindenberg A, Murphy D, Rolls E, Saletu B, Spedding M, Sweeney J, Whittington M, Young LJ. Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov. 2012 Feb 01; 11(2):141-68. PMID: 22293568.
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      76. Halberstadt AL, Nichols DE, Geyer M. Behavioral effects of a,a,ß,ß-tetradeutero-5-MeO-DMT in rats: comparison with 5-MeO-DMT administered in combination with a monoamine oxidase inhibitor. Psychopharmacology (Berl). 2012 Jun; 221(4):709-18. PMID: 22222861; PMCID: PMC3796951.
      77. Ahmari SE, Risbrough VB, Geyer M, Simpson HB. Impaired sensorimotor gating in unmedicated adults with obsessive-compulsive disorder. Neuropsychopharmacology. 2012 Apr; 37(5):1216-23. PMID: 22218093; PMCID: PMC3306882.
      78. Powell SB, Weber M, Geyer M. Genetic models of sensorimotor gating: relevance to neuropsychiatric disorders. Curr Top Behav Neurosci. 2012; 12:251-318. PMID: 22367921; PMCID: PMC3357439.
      79. Young JW, Amitai N, Geyer M. Behavioral animal models to assess pro-cognitive treatments for schizophrenia. Handb Exp Pharmacol. 2012; (213):39-79. PMID: 23027412.
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      80. George D, El-Mallawany NK, Jin Z, Geyer M, Della-Latta P, Satwani P, Garvin JH, Bradley MB, Bhatia M, van de Ven C, Morris E, Schwartz J, Cairo MS. Adenovirus infection in paediatric allogeneic stem cell transplantation recipients is a major independent factor for significantly increasing the risk of treatment related mortality. Br J Haematol. 2012 Jan; 156(1):99-108. PMID: 22008222.
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      81. Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer M, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, Law AJ, Campbell B, Krystal JH, Moghaddam B, Sawa A, Saw A, Caron MG, George SR, Allen JA, Solis M. Advancing drug discovery for schizophrenia. Ann N Y Acad Sci. 2011 Oct; 1236:30-43. PMID: 22032400; PMCID: PMC3787879.
      82. Young JW, Henry BL, Geyer M. Predictive animal models of mania: hits, misses and future directions. Br J Pharmacol. 2011 Oct; 164(4):1263-84. PMID: 21410454; PMCID: PMC3229761.
      83. Quednow BB, Kometer M, Geyer M, Vollenweider FX. Psilocybin-induced deficits in automatic and controlled inhibition are attenuated by ketanserin in healthy human volunteers. Neuropsychopharmacology. 2012 Feb; 37(3):630-40. PMID: 21956447; PMCID: PMC3260978.
      84. Holstein DH, Csomor PA, Geyer M, Huber T, Brugger N, Studerus E, Vollenweider FX. The effects of sertindole on sensory gating, sensorimotor gating, and cognition in healthy volunteers. J Psychopharmacol. 2011 Dec; 25(12):1600-13. PMID: 21890590.
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      85. Butler PD, Chen Y, Ford JM, Geyer M, Silverstein SM, Green MF. Perceptual measurement in schizophrenia: promising electrophysiology and neuroimaging paradigms from CNTRICS. Schizophr Bull. 2012 Jan; 38(1):81-91. PMID: 21890745; PMCID: PMC3245585.
      86. Minassian A, Henry BL, Young JW, Masten V, Geyer M, Perry W. Repeated assessment of exploration and novelty seeking in the human behavioral pattern monitor in bipolar disorder patients and healthy individuals. PLoS One. 2011; 6(8):e24185. PMID: 21912623; PMCID: PMC3166173.
      87. Tanaka S, Young JW, Gresack JE, Geyer M, Risbrough VB. Factor analysis of attentional set-shifting performance in young and aged mice. Behav Brain Funct. 2011 Aug 12; 7:33. PMID: 21838910; PMCID: PMC3174878.
      88. Chung S, Verheij MM, Hesseling P, van Vugt RW, Buell M, Belluzzi JD, Geyer M, Martens GJ, Civelli O. The melanin-concentrating hormone (MCH) system modulates behaviors associated with psychiatric disorders. PLoS One. 2011; 6(7):e19286. PMID: 21818251; PMCID: PMC3139593.
      89. Young JW, Meves JM, Tarantino IS, Caldwell S, Geyer M. Delayed procedural learning in a7-nicotinic acetylcholine receptor knockout mice. Genes Brain Behav. 2011 Oct; 10(7):720-33. PMID: 21679297; PMCID: PMC3918170.
      90. Young JW, Powell SB, Geyer M. Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology. 2012 Mar; 62(3):1381-90. PMID: 21726569; PMCID: PMC3217063.
      91. Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer M, Niculescu AB. Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. Transl Psychiatry. 2011 May 24; 1:e9. PMID: 22832404; PMCID: PMC3309477.
      92. Carter CS, Barch DM, Bullmore E, Breiling J, Buchanan RW, Butler P, Cohen JD, Geyer M, Gollub R, Green MF, Jaeger J, Krystal JH, Moore H, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T. Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: developing imaging biomarkers to enhance treatment development for schizophrenia and related disorders. Biol Psychiatry. 2011 Jul 01; 70(1):7-12. PMID: 21529781; PMCID: PMC3116022.
      93. Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer M, Rodd ZA, Niculescu AB. Convergent functional genomic studies of ?-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Transl Psychiatry. 2011 Apr 26; 1:e4. PMID: 22832392; PMCID: PMC3309466.
      94. Young JW, Powell SB, Scott CN, Zhou X, Geyer M. The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding. Behav Brain Res. 2011 Sep 12; 222(1):183-92. PMID: 21458500; PMCID: PMC3531561.
      95. Young JW, van Enkhuizen J, Winstanley CA, Geyer M. Increased risk-taking behavior in dopamine transporter knockdown mice: further support for a mouse model of mania. J Psychopharmacol. 2011 Jul; 25(7):934-43. PMID: 21421642; PMCID: PMC3568506.
      96. Young JW, Kooistra K, Geyer M. Dopamine receptor mediation of the exploratory/hyperactivity effects of modafinil. Neuropsychopharmacology. 2011 Jun; 36(7):1385-96. PMID: 21412225; PMCID: PMC3096808.
      97. Reissner V, Kokkevi A, Schifano F, Room R, Storbjörk J, Stohler R, DiFuria L, Rehm J, Geyer M, Hölscher F, Scherbaum N. Differences in drug consumption, comorbidity and health service use of opioid addicts across six European urban regions (TREAT-project). Eur Psychiatry. 2012 Aug; 27(6):455-62. PMID: 21277750.
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      98. Henry BL, Minassian A, van Rhenen M, Young JW, Geyer M, Perry W. Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm. Psychopharmacology (Berl). 2011 Jun; 215(4):697-707. PMID: 21279333; PMCID: PMC3102201.
      99. Halberstadt AL, Geyer M. Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens. Neuropharmacology. 2011 Sep; 61(3):364-81. PMID: 21256140; PMCID: PMC3110631.
      100. Tarantino IS, Sharp RF, Geyer M, Meves JM, Young JW. Working memory span capacity improved by a D2 but not D1 receptor family agonist. Behav Brain Res. 2011 Jun 01; 219(2):181-8. PMID: 21232557; PMCID: PMC3073724.
      101. Geyer M, Howell-Jones R, Cunningham R, McNulty C. Consensus of microbiology reporting of ear swab results to primary care clinicians in patients with otitis externa. Br J Biomed Sci. 2011; 68(4):174-80. PMID: 22263430.
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      102. Halberstadt AL, Lehmann-Masten VD, Geyer M, Powell SB. Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice. Psychopharmacology (Berl). 2011 May; 215(1):81-92. PMID: 21153406; PMCID: PMC3072483.
      103. Halberstadt AL, Koedood L, Powell SB, Geyer M. Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice. J Psychopharmacol. 2011 Nov; 25(11):1548-61. PMID: 21148021; PMCID: PMC3531560.
      104. Ali SS, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer M, Dugan LL, Risbrough VB. Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Res. 2011 Jan 12; 1368:65-70. PMID: 21075081; PMCID: PMC3018762.
      105. Semenova S, Hoyer D, Geyer M, Markou A. Somatostatin-28 modulates prepulse inhibition of the acoustic startle response, reward processes and spontaneous locomotor activity in rats. Neuropeptides. 2010 Oct; 44(5):421-9. PMID: 20537385; PMCID: PMC3215674.
      106. Bailer UF, Bloss CS, Frank GK, Price JC, Meltzer CC, Mathis CA, Geyer M, Wagner A, Becker CR, Schork NJ, Kaye WH. 5-HT1A receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups. Int J Eat Disord. 2011 Sep; 44(6):477-87. PMID: 20872754; PMCID: PMC4286242.
      107. Markou A, Geyer M. Studies in genetically modified mice suggest novel mechanisms of mood regulation. Biol Psychiatry. 2010 Sep 15; 68(6):500-2. PMID: 20797461; PMCID: PMC2929529.
      108. Zhou X, Nie Z, Roberts A, Zhang D, Sebat J, Malhotra D, Kelsoe JR, Geyer M. Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disorders. Hum Mol Genet. 2010 Oct 01; 19(19):3797-805. PMID: 20634195; PMCID: PMC2935857.
      109. Perry W, Minassian A, Henry B, Kincaid M, Young JW, Geyer M. Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm. Psychiatry Res. 2010 Jun 30; 178(1):84-91. PMID: 20471103; PMCID: PMC2914139.
      110. Gresack J, Powell S, Geyer M, Poore MS, Coste S, Risbrough V. CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice. Neuropeptides. 2010 Aug; 44(4):349-53. PMID: 20466421; PMCID: PMC2888500.
      111. Young JW, Powell SB, Geyer M, Jeste DV, Risbrough VB. The mouse attentional-set-shifting task: a method for assaying successful cognitive aging? Cogn Affect Behav Neurosci. 2010 May; 10(2):243-51. PMID: 20498348; PMCID: PMC2877277.
      112. Henry BL, Minassian A, Young JW, Paulus MP, Geyer M, Perry W. Cross-species assessments of motor and exploratory behavior related to bipolar disorder. Neurosci Biobehav Rev. 2010 Jul; 34(8):1296-306. PMID: 20398694; PMCID: PMC2900445.
      113. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer M. The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav. 2010 Jul; 96(1):7-15. PMID: 20363246; PMCID: PMC2878916.
      114. Zhou X, Chen Q, Schaukowitch K, Kelsoe JR, Geyer M. Insoluble DISC1-Boymaw fusion proteins generated by DISC1 translocation. Mol Psychiatry. 2010 Jul; 15(7):669-72. PMID: 20351725; PMCID: PMC2891102.
      115. Chang WL, Geyer M, Buell MR, Weber M, Swerdlow NR. The effects of pramipexole on prepulse inhibition and locomotor activity in C57BL/6J mice. Behav Pharmacol. 2010 Mar; 21(2):135-43. PMID: 20215963; PMCID: PMC2890261.
      116. Young JW, Geyer M. Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors? Biol Psychiatry. 2010 Apr 15; 67(8):784-7. PMID: 20132929; PMCID: PMC2849918.
      117. Young JW, Wallace CK, Geyer M, Risbrough VB. Age-associated improvements in cross-modal prepulse inhibition in mice. Behav Neurosci. 2010 Feb; 124(1):133-140. PMID: 20141288; PMCID: PMC3088993.
      118. Gresack JE, Risbrough VB, Scott CN, Coste S, Stenzel-Poore M, Geyer M, Powell SB. Isolation rearing-induced deficits in contextual fear learning do not require CRF(2) receptors. Behav Brain Res. 2010 May 01; 209(1):80-4. PMID: 20097235; PMCID: PMC2832092.
      119. Young JW, Zhou X, Geyer M. Animal models of schizophrenia. Curr Top Behav Neurosci. 2010; 4:391-433. PMID: 21312408.
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      120. Minassian A, Henry BL, Geyer M, Paulus MP, Young JW, Perry W. The quantitative assessment of motor activity in mania and schizophrenia. J Affect Disord. 2010 Jan; 120(1-3):200-6. PMID: 19435640; PMCID: PMC2795051.
      121. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer M. GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl). 2010 Feb; 208(3):443-54. PMID: 20020109; PMCID: PMC2806531.
      122. Hilti CC, Delko T, Orosz AT, Thomann K, Ludewig S, Geyer M, Vollenweider FX, Feldon J, Cattapan-Ludewig K. Sustained attention and planning deficits but intact attentional set-shifting in neuroleptic-naïve first-episode schizophrenia patients. Neuropsychobiology. 2010; 61(2):79-86. PMID: 20016226; PMCID: PMC2837882.
      123. Halberstadt AL, Geyer M. LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor. Psychopharmacology (Berl). 2010 Feb; 208(2):179-89. PMID: 19937319.
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      124. Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C, Yehyawi N, Lysaker P, Dustin J, Caligiuri M, Lohr J, Lahiri DK, Nurnberger JI, Faraone SV, Geyer M, Tsuang MT, Schork NJ, Salomon DR, Niculescu AB. Identification of blood biomarkers for psychosis using convergent functional genomics. Mol Psychiatry. 2011 Jan; 16(1):37-58. PMID: 19935739.
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      125. Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ, Henry BL, Zhuang X, Masten VL, Sharp RF, Geyer M. A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry. 2009 Oct; 66(10):1072-80. PMID: 19805697; PMCID: PMC2897252.
      126. Henry BL, Minassian A, Paulus MP, Geyer M, Perry W. Heart rate variability in bipolar mania and schizophrenia. J Psychiatr Res. 2010 Feb; 44(3):168-76. PMID: 19700172; PMCID: PMC2822123.
      127. Suzuki G, Harper KM, Hiramoto T, Funke B, Lee M, Kang G, Buell M, Geyer M, Kucherlapati R, Morrow B, Männistö PT, Agatsuma S, Hiroi N. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Hum Mol Genet. 2009 Oct 15; 18(20):3914-25. PMID: 19617637; PMCID: PMC2748897.
      128. Ruderman MA, Powell SB, Geyer M. A Kappa Opioid Model of Atypical Altered Consciousness and Psychosis: U50488, DOI, AC90179 Effects on Prepulse Inhibition and Locomotion in Mice. J Young Investig. 2009 Jul 01; 19(13):1-7. PMID: 25346645.
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      129. Duvvuri V, Risbrough VB, Kaye WH, Geyer M. 5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition. Pharmacol Biochem Behav. 2009 Sep; 93(3):349-53. PMID: 19490926; PMCID: PMC2724836.
      130. Marston HM, Young JW, Martin FD, Serpa KA, Moore CL, Wong EH, Gold L, Meltzer LT, Azar MR, Geyer M, Shahid M. Asenapine effects in animal models of psychosis and cognitive function. Psychopharmacology (Berl). 2009 Nov; 206(4):699-714. PMID: 19462162; PMCID: PMC2755103.
      131. Powell SB, Zhou X, Geyer M. Prepulse inhibition and genetic mouse models of schizophrenia. Behav Brain Res. 2009 Dec 07; 204(2):282-94. PMID: 19397931; PMCID: PMC2735602.
      132. Zhou X, Tang W, Greenwood TA, Guo S, He L, Geyer M, Kelsoe JR. Transcription factor SP4 is a susceptibility gene for bipolar disorder. PLoS One. 2009; 4(4):e5196. PMID: 19401786; PMCID: PMC2674320.
      133. Halberstadt AL, van der Heijden I, Ruderman MA, Risbrough VB, Gingrich JA, Geyer M, Powell SB. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology. 2009 Jul; 34(8):1958-67. PMID: 19322172; PMCID: PMC2697271.
      134. Young JW, Powell SB, Risbrough V, Marston HM, Geyer M. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther. 2009 May; 122(2):150-202. PMID: 19269307; PMCID: PMC2688712.
      135. Suzuki G, Harper KM, Hiramoto T, Sawamura T, Lee M, Kang G, Tanigaki K, Buell M, Geyer M, Trimble WS, Agatsuma S, Hiroi N. Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. Hum Mol Genet. 2009 May 01; 18(9):1652-60. PMID: 19240081; PMCID: PMC2733818.
      136. Young JW, Light GA, Marston HM, Sharp R, Geyer M. The 5-choice continuous performance test: evidence for a translational test of vigilance for mice. PLoS One. 2009; 4(1):e4227. PMID: 19156216; PMCID: PMC2626630.
      137. Green MF, Butler PD, Chen Y, Geyer M, Silverstein S, Wynn JK, Yoon JH, Zemon V. Perception measurement in clinical trials of schizophrenia: promising paradigms from CNTRICS. Schizophr Bull. 2009 Jan; 35(1):163-81. PMID: 19023123; PMCID: PMC2635893.
      138. Barch DM, Carter CS, Arnsten A, Buchanan RW, Cohen JD, Geyer M, Green MF, Krystal JH, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Selecting paradigms from cognitive neuroscience for translation into use in clinical trials: proceedings of the third CNTRICS meeting. Schizophr Bull. 2009 Jan; 35(1):109-14. PMID: 19023126; PMCID: PMC2643950.
      139. Risbrough VB, Geyer M, Hauger RL, Coste S, Stenzel-Poore M, Wurst W, Holsboer F. CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues. Neuropsychopharmacology. 2009 May; 34(6):1494-503. PMID: 19020499; PMCID: PMC2900918.
      140. Shanahan NA, Holick Pierz KA, Masten VL, Waeber C, Ansorge M, Gingrich JA, Geyer M, Hen R, Dulawa SC. Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry. 2009 Mar 01; 65(5):401-8. PMID: 19013555; PMCID: PMC2674010.
      141. Rankin CH, Abrams T, Barry RJ, Bhatnagar S, Clayton DF, Colombo J, Coppola G, Geyer M, Glanzman DL, Marsland S, McSweeney FK, Wilson DA, Wu CF, Thompson RF. Habituation revisited: an updated and revised description of the behavioral characteristics of habituation. Neurobiol Learn Mem. 2009 Sep; 92(2):135-8. PMID: 18854219; PMCID: PMC2754195.
      142. Markou A, Chiamulera C, Geyer M, Tricklebank M, Steckler T. Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology. 2009 Jan; 34(1):74-89. PMID: 18830240; PMCID: PMC2651739.
      143. Geyer M, Manrique I, Degen L, Beglinger C. Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers. Digestion. 2008; 78(1):30-3. PMID: 18781073.
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      144. Powell SB, Young JW, Ong JC, Caron MG, Geyer M. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol. 2008 Sep; 19(5-6):562-5. PMID: 18690110; PMCID: PMC2693185.
      145. Geyer M, Vollenweider FX. Serotonin research: contributions to understanding psychoses. Trends Pharmacol Sci. 2008 Sep; 29(9):445-53. PMID: 19086254.
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      146. Geyer M. Developing translational animal models for symptoms of schizophrenia or bipolar mania. Neurotox Res. 2008 Aug; 14(1):71-8. PMID: 18790726; PMCID: PMC2667110.
      147. Halberstadt AL, Geyer M. Habituation and sensitization of acoustic startle: opposite influences of dopamine D1 and D2-family receptors. Neurobiol Learn Mem. 2009 Sep; 92(2):243-8. PMID: 18644244; PMCID: PMC2745310.
      148. Halberstadt AL, Buell MR, Masten VL, Risbrough VB, Geyer M. Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. Psychopharmacology (Berl). 2008 Nov; 201(1):55-66. PMID: 18604652; PMCID: PMC2929165.
      149. Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative. Biol Psychiatry. 2008 Jul 01; 64(1):4-10. PMID: 18466880; PMCID: PMC2577821.
      150. Zhou X, Geyer M, Kelsoe JR. Does disrupted-in-schizophrenia (DISC1) generate fusion transcripts? Mol Psychiatry. 2008 Apr; 13(4):361-3. PMID: 18347596; PMCID: PMC2771200.
      151. Le-Niculescu H, McFarland MJ, Ogden CA, Balaraman Y, Patel S, Tan J, Rodd ZA, Paulus M, Geyer M, Edenberg HJ, Glatt SJ, Faraone SV, Nurnberger JI, Kuczenski R, Tsuang MT, Niculescu AB. Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 05; 147B(2):134-66. PMID: 18247375.
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      152. Kumari V, Antonova E, Geyer M. Prepulse inhibition and "psychosis-proneness" in healthy individuals: an fMRI study. Eur Psychiatry. 2008 Jun; 23(4):274-80. PMID: 18222069.
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      153. Kumari V, Fannon D, Geyer M, Premkumar P, Antonova E, Simmons A, Kuipers E. Cortical grey matter volume and sensorimotor gating in schizophrenia. Cortex. 2008 Oct; 44(9):1206-14. PMID: 18761134; PMCID: PMC2845812.
      154. Doherty JM, Masten VL, Powell SB, Ralph RJ, Klamer D, Low MJ, Geyer M. Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology. 2008 Oct; 33(11):2648-56. PMID: 18075489.
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      155. Jonkman S, Risbrough VB, Geyer M, Markou A. Spontaneous nicotine withdrawal potentiates the effects of stress in rats. Neuropsychopharmacology. 2008 Aug; 33(9):2131-8. PMID: 18033237; PMCID: PMC2648847.
      156. Kask K, Gulinello M, Bäckström T, Geyer M, Sundström-Poromaa I. Patients with premenstrual dysphoric disorder have increased startle response across both cycle phases and lower levels of prepulse inhibition during the late luteal phase of the menstrual cycle. Neuropsychopharmacology. 2008 Aug; 33(9):2283-90. PMID: 17940552.
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      157. Geyer M, Tamminga CA. Wayne Fenton's impact on academic neuroscience. Schizophr Bull. 2007 Sep; 33(5):1156-9. PMID: 17617663; PMCID: PMC2632348.
      158. Young JW, Minassian A, Paulus MP, Geyer M, Perry W. A reverse-translational approach to bipolar disorder: rodent and human studies in the Behavioral Pattern Monitor. Neurosci Biobehav Rev. 2007; 31(6):882-96. PMID: 17706782; PMCID: PMC2025688.
      159. Semenova S, Geyer M, Sutcliffe JG, Markou A, Hedlund PB. Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition. Biol Psychiatry. 2008 Jan 01; 63(1):98-105. PMID: 17531208; PMCID: PMC2174622.
      160. Heekeren K, Neukirch A, Daumann J, Stoll M, Obradovic M, Kovar KA, Geyer M, Gouzoulis-Mayfrank E. Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis. J Psychopharmacol. 2007 May; 21(3):312-20. PMID: 17591658.
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      161. Csomor PA, Stadler RR, Feldon J, Yee BK, Geyer M, Vollenweider FX. Haloperidol differentially modulates prepulse inhibition and p50 suppression in healthy humans stratified for low and high gating levels. Neuropsychopharmacology. 2008 Feb; 33(3):497-512. PMID: 17460616.
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      162. Powell SB, Geyer M. Overview of animal models of schizophrenia. Curr Protoc Neurosci. 2007 Apr; Chapter 9:Unit 9.24. PMID: 18428667.
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      163. Le-Niculescu H, Balaraman Y, Patel S, Tan J, Sidhu K, Jerome RE, Edenberg HJ, Kuczenski R, Geyer M, Nurnberger JI, Faraone SV, Tsuang MT, Niculescu AB. Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 05; 144B(2):129-58. PMID: 17266109.
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      164. Harte MK, Powell SB, Swerdlow NR, Geyer M, Reynolds GP. Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats. J Neural Transm (Vienna). 2007 Jul; 114(7):893-8. PMID: 17594127.
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      165. Abel KM, Allin M, van Amelsvoort T, Hemsley D, Geyer M. The indirect serotonergic agonist d-fenfluramine and prepulse inhibition in healthy men. Neuropharmacology. 2007 Mar; 52(4):1088-94. PMID: 17306313.
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      166. Vollenweider FX, Csomor PA, Knappe B, Geyer M, Quednow BB. The effects of the preferential 5-HT2A agonist psilocybin on prepulse inhibition of startle in healthy human volunteers depend on interstimulus interval. Neuropsychopharmacology. 2007 Sep; 32(9):1876-87. PMID: 17299516.
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      167. Vinkers CH, Risbrough VB, Geyer M, Caldwell S, Low MJ, Hauger RL. Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating. Pharmacol Biochem Behav. 2007 Mar; 86(3):550-8. PMID: 17324452; PMCID: PMC1892615.
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      169. Krebs-Thomson K, Ruiz EM, Masten V, Buell M, Geyer M. The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl). 2006 Dec; 189(3):319-29. PMID: 17013638.
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      170. McDowell JE, Brown GG, Lazar N, Camchong J, Sharp R, Krebs-Thomson K, Eyler LT, Braff DL, Geyer M. The neural correlates of habituation of response to startling tactile stimuli presented in a functional magnetic resonance imaging environment. Psychiatry Res. 2006 Nov 22; 148(1):1-10. PMID: 17000088.
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      171. Kumari V, Antonova E, Geyer M, Ffytche D, Williams SC, Sharma T. A fMRI investigation of startle gating deficits in schizophrenia patients treated with typical or atypical antipsychotics. Int J Neuropsychopharmacol. 2007 Aug; 10(4):463-77. PMID: 16923324.
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      172. Zhou X, Qyang Y, Kelsoe JR, Masliah E, Geyer M. Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant mice. Genes Brain Behav. 2007 Apr; 6(3):269-76. PMID: 16899055.
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      173. Oranje B, Geyer M, Bocker KB, Leon Kenemans J, Verbaten MN. Prepulse inhibition and P50 suppression: commonalities and dissociations. Psychiatry Res. 2006 Aug 30; 143(2-3):147-58. PMID: 16879870.
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      174. Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer M. Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology. 2006 Nov; 31(11):2349-58. PMID: 16855533.
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      175. Barr AM, Powell SB, Markou A, Geyer M. Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology. 2006 Sep; 51(3):457-65. PMID: 16762376.
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      176. Geyer M, Stamenic I, Bühler H, Bertschinger P. [Epidemiology of gastrointestinal bleeding in the elderly]. Praxis (Bern 1994). 2006 May 10; 95(19):757-65. PMID: 16722204.
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      177. Moore H, Jentsch JD, Ghajarnia M, Geyer M, Grace AA. A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biol Psychiatry. 2006 Aug 01; 60(3):253-64. PMID: 16581031; PMCID: PMC3396156.
      178. Swerdlow NR, Geyer M, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology. 2006 Mar; 31(3):506-15. PMID: 16123772; PMCID: PMC1373667.
      179. Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer M, Tolf BR, Brann MR, Davis RE. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist. J Pharmacol Exp Ther. 2006 May; 317(2):910-8. PMID: 16469866.
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      180. Postma P, Gray JA, Sharma T, Geyer M, Mehrotra R, Das M, Zachariah E, Hines M, Williams SC, Kumari V. A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia. Psychopharmacology (Berl). 2006 Mar; 184(3-4):589-99. PMID: 16456657.
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      181. Varty GB, Powell SB, Lehmann-Masten V, Buell MR, Geyer M. Isolation rearing of mice induces deficits in prepulse inhibition of the startle response. Behav Brain Res. 2006 Apr 25; 169(1):162-7. PMID: 16406103.
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      182. Geyer M. Are cross-species measures of sensorimotor gating useful for the discovery of procognitive cotreatments for schizophrenia? Dialogues Clin Neurosci. 2006; 8(1):9-16. PMID: 16640109; PMCID: PMC3181759.
      183. Albani C, Gunzelmann T, Schmutzer G, Grulke N, Bailer H, Blaser G, Geyer M, Brähler E. [The emotional sensitivity of elderly people--validation of the Profile of Mood States for people over 60 years]. Z Gerontol Geriatr. 2005 Dec; 38(6):431-40. PMID: 16362559.
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      184. Geyer M, Heinssen R. New approaches to measurement and treatment research to improve cognition in schizophrenia. Schizophr Bull. 2005 Oct; 31(4):806-9. PMID: 16166608.
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      185. Ong JC, Brody SA, Large CH, Geyer M. An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition. J Pharmacol Exp Ther. 2005 Dec; 315(3):1163-71. PMID: 16123308.
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      186. Floresco SB, Geyer M, Gold LH, Grace AA. Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia. Schizophr Bull. 2005 Oct; 31(4):888-94. PMID: 16079387.
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      187. de Jongh R, Geyer M, Olivier B, Groenink L. The effects of sex and neonatal maternal separation on fear-potentiated and light-enhanced startle. Behav Brain Res. 2005 Jun 20; 161(2):190-6. PMID: 15878207.
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      188. Meincke U, Light GA, Geyer M, Braff DL. On the waveform of the acoustic startle blink in the paradigm of prepulse inhibition - methodological and physiological aspects. Neuropsychobiology. 2005; 52(1):24-7. PMID: 15942260.
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      189. Brody SA, Nakanishi N, Tu S, Lipton SA, Geyer M. A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle. Biol Psychiatry. 2005 May 15; 57(10):1147-52. PMID: 15866554.
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      190. Zhou X, Long JM, Geyer M, Masliah E, Kelsoe JR, Wynshaw-Boris A, Chien KR. Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Mol Psychiatry. 2005 Apr; 10(4):393-406. PMID: 15558077.
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      191. Powell SB, Palomo J, Carasso BS, Bakshi VP, Geyer M. Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors. Psychopharmacology (Berl). 2005 Jul; 180(3):491-500. PMID: 15719216.
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      192. Ludewig S, Geyer M, Ramseier M, Vollenweider FX, Rechsteiner E, Cattapan-Ludewig K. Information-processing deficits and cognitive dysfunction in panic disorder. J Psychiatry Neurosci. 2005 Jan; 30(1):37-43. PMID: 15644996; PMCID: PMC543839.
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      194. Meincke U, Mörth D, Voss T, Thelen B, Geyer M, Gouzoulis-Mayfrank E. Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis--a longitudinal study. Eur Arch Psychiatry Clin Neurosci. 2004 Dec; 254(6):415-21. PMID: 15538598.
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      195. Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer M, Lohr JB, Kuczenski R, Niculescu AB. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry. 2004 Nov; 9(11):1007-29. PMID: 15314610.
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      196. Erhardt S, Schwieler L, Emanuelsson C, Geyer M. Endogenous kynurenic acid disrupts prepulse inhibition. Biol Psychiatry. 2004 Aug 15; 56(4):255-60. PMID: 15312813.
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      197. Harte MK, Powell SB, Reynolds LM, Swerdlow NR, Geyer M, Reynolds GP. Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation. Biol Psychiatry. 2004 Aug 15; 56(4):296-9. PMID: 15312819.
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      198. Risbrough VB, Hauger RL, Roberts AL, Vale WW, Geyer M. Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior. J Neurosci. 2004 Jul 21; 24(29):6545-52. PMID: 15269266.
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      199. Powell SB, Geyer M, Gallagher D, Paulus MP. The balance between approach and avoidance behaviors in a novel object exploration paradigm in mice. Behav Brain Res. 2004 Jul 09; 152(2):341-9. PMID: 15196802.
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      200. Abel KM, Jolley S, Hemsley DR, Geyer M. The influence of schizotypy traits on prepulse inhibition in young healthy controls. J Psychopharmacol. 2004 Jun; 18(2):181-8. PMID: 15260905.
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      201. Meincke U, Light GA, Geyer M, Braff DL, Gouzoulis-Mayfrank E. Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia. Psychiatry Res. 2004 Apr 15; 126(1):51-61. PMID: 15081627.
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      202. Barr AM, Lehmann-Masten V, Paulus M, Gainetdinov RR, Caron MG, Geyer M. The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology. 2004 Feb; 29(2):221-8. PMID: 14603268.
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      203. Powell SB, Lehmann-Masten VD, Paulus MP, Gainetdinov RR, Caron MG, Geyer M. MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice. Psychopharmacology (Berl). 2004 May; 173(3-4):310-7. PMID: 14747902.
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      204. Heekeren K, Daumann J, Geyer M, Gouzoulis-Mayfrank E. Plasticity of the acoustic startle reflex in currently abstinent ecstasy (MDMA) users. Psychopharmacology (Berl). 2004 May; 173(3-4):418-24. PMID: 14722707.
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      205. Heekeren K, Meincke U, Geyer M, Gouzoulis-Mayfrank E. Attentional modulation of prepulse inhibition: a new startle paradigm. Neuropsychobiology. 2004; 49(2):88-93. PMID: 14981340.
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      206. Brody SA, Dulawa SC, Conquet F, Geyer M. Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors. Mol Psychiatry. 2004 Jan; 9(1):35-41. PMID: 14699440.
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      207. Brody SA, Geyer M. Interactions of the mGluR5 gene with breeding and maternal factors on startle and prepulse inhibition in mice. Neurotox Res. 2004; 6(1):79-90. PMID: 15184109.
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      208. Brody SA, Conquet F, Geyer M. Disruption of prepulse inhibition in mice lacking mGluR1. Eur J Neurosci. 2003 Dec; 18(12):3361-6. PMID: 14686909.
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      209. Brody SA, Conquet F, Geyer M. Effect of antipsychotic treatment on the prepulse inhibition deficit of mGluR5 knockout mice. Psychopharmacology (Berl). 2004 Mar; 172(2):187-95. PMID: 14615875.
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      210. Geyer M, Dulawa SC. Assessment of murine startle reactivity, prepulse inhibition, and habituation. Curr Protoc Neurosci. 2003 Nov; Chapter 8:Unit 8.17. PMID: 18428584.
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      211. Dirks A, Groenink L, Westphal KG, Olivier JD, Verdouw PM, van der Gugten J, Geyer M, Olivier B. Reversal of startle gating deficits in transgenic mice overexpressing corticotropin-releasing factor by antipsychotic drugs. Neuropsychopharmacology. 2003 Oct; 28(10):1790-8. PMID: 12865891.
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      212. Geyer M, Ellenbroek B. Animal behavior models of the mechanisms underlying antipsychotic atypicality. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Oct; 27(7):1071-9. PMID: 14642967.
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      213. Harvey PD, Geyer M, Robbins TW, Krystal JH. Cognition in schizophrenia: from basic science to clinical treatment. Psychopharmacology (Berl). 2003 Sep; 169(3-4):213-4. PMID: 12955286.
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      214. Hessel A, Geyer M, Gunzelmann T, Schumacher J, Brähler E. [Somatoform complaints in elderly of Germany]. Z Gerontol Geriatr. 2003 Aug; 36(4):287-96. PMID: 12937934.
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      215. Ludewig K, Geyer M, Vollenweider FX. Deficits in prepulse inhibition and habituation in never-medicated, first-episode schizophrenia. Biol Psychiatry. 2003 Jul 15; 54(2):121-8. PMID: 12873801.
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      216. Risbrough VB, Hauger RL, Pelleymounter MA, Geyer M. Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice. Psychopharmacology (Berl). 2003 Nov; 170(2):178-87. PMID: 12845406.
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      217. Ludewig K, Ludewig S, Seitz A, Obrist M, Geyer M, Vollenweider FX. The acoustic startle reflex and its modulation: effects of age and gender in humans. Biol Psychol. 2003 Jul; 63(3):311-23. PMID: 12853174.
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      218. Abel KM, Allin MP, Hemsley DR, Geyer M. Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology. 2003 May; 44(6):729-37. PMID: 12681371.
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      219. Brody SA, Geyer M, Large CH. Lamotrigine prevents ketamine but not amphetamine-induced deficits in prepulse inhibition in mice. Psychopharmacology (Berl). 2003 Sep; 169(3-4):240-6. PMID: 12698229.
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      220. Körner A, Geyer M, Gunzelmann T, Brähler E. [The influence of socio-demographic factors on personality dimensions in the elderly]. Z Gerontol Geriatr. 2003 Apr; 36(2):130-7. PMID: 12720026.
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      221. Ellwanger J, Geyer M, Braff DL. The relationship of age to prepulse inhibition and habituation of the acoustic startle response. Biol Psychol. 2003 Mar; 62(3):175-95. PMID: 12633977.
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      222. Powell SB, Paulus MP, Hartman DS, Godel T, Geyer M. RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology. 2003 Mar; 44(4):473-81. PMID: 12646284.
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      223. Kumari V, Gray JA, Geyer M, ffytche D, Soni W, Mitterschiffthaler MT, Vythelingum GN, Simmons A, Williams SC, Sharma T. Neural correlates of tactile prepulse inhibition: a functional MRI study in normal and schizophrenic subjects. Psychiatry Res. 2003 Feb 15; 122(2):99-113. PMID: 12714174.
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      224. Ralph-Williams RJ, Paulus MP, Zhuang X, Hen R, Geyer M. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biol Psychiatry. 2003 Feb 15; 53(4):352-9. PMID: 12586455.
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      225. Powell SB, Geyer M, Preece MA, Pitcher LK, Reynolds GP, Swerdlow NR. Dopamine depletion of the nucleus accumbens reverses isolation-induced deficits in prepulse inhibition in rats. Neuroscience. 2003; 119(1):233-40. PMID: 12763084.
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      226. Ralph-Williams RJ, Lehmann-Masten V, Geyer M. Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice. Neuropsychopharmacology. 2003 Jan; 28(1):108-18. PMID: 12496946.
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      227. Henry SA, Lehmann-Masten V, Gasparini F, Geyer M, Markou A. The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity. Neuropharmacology. 2002 Dec; 43(8):1199-209. PMID: 12527469.
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      228. Ralph-Williams RJ, Lehmann-Masten V, Otero-Corchon V, Low MJ, Geyer M. Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice. J Neurosci. 2002 Nov 01; 22(21):9604-11. PMID: 12417685.
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      229. Risbrough VB, Brodkin JD, Geyer M. GABA-A and 5-HT1A receptor agonists block expression of fear-potentiated startle in mice. Neuropsychopharmacology. 2003 Apr; 28(4):654-63. PMID: 12655310.
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      231. Swerdlow NR, Shoemaker JM, Stephany N, Wasserman L, Ro HJ, Geyer M. Prestimulus effects on startle magnitude: sensory or motor? Behav Neurosci. 2002 Aug; 116(4):672-81. PMID: 12148934.
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      232. Powell SB, Geyer M. Developmental markers of psychiatric disorders as identified by sensorimotor gating. Neurotox Res. 2002 Aug-Sep; 4(5-6):489-502. PMID: 12754162.
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      233. Cadenhead KS, Light GA, Geyer M, McDowell JE, Braff DL. Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype? Am J Psychiatry. 2002 May; 159(5):869-71. PMID: 11986147.
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      234. Ludewig K, Geyer M, Etzensberger M, Vollenweider FX. Stability of the acoustic startle reflex, prepulse inhibition, and habituation in schizophrenia. Schizophr Res. 2002 May 01; 55(1-2):129-37. PMID: 11955972.
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      235. Dirks A, Groenink L, Schipholt MI, van der Gugten J, Hijzen TH, Geyer M, Olivier B. Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone. Biol Psychiatry. 2002 Apr 01; 51(7):583-90. PMID: 11950460.
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      236. Vollenweider FX, Liechti ME, Gamma A, Greer G, Geyer M. Acute psychological and neurophysiological effects of MDMA in humans. J Psychoactive Drugs. 2002 Apr-Jun; 34(2):171-84. PMID: 12691207.
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      237. Martinez-Price DL, Geyer M. Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats. Pharmacol Biochem Behav. 2002 Apr; 71(4):569-80. PMID: 11888548.
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      238. Swerdlow NR, Eastvold A, Karban B, Ploum Y, Stephany N, Geyer M, Cadenhead K, Auerbach PP. Dopamine agonist effects on startle and sensorimotor gating in normal male subjects: time course studies. Psychopharmacology (Berl). 2002 May; 161(2):189-201. PMID: 11981599.
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      239. Martinez ZA, Platten A, Pollack E, Shoemaker J, Ro H, Pitcher L, Geyer M, Swerdlow NR. "Typical" but not "atypical" antipsychotic effects on startle gating deficits in prepubertal rats. Psychopharmacology (Berl). 2002 Apr; 161(1):38-46. PMID: 11967629.
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      240. Geyer M, McIlwain KL, Paylor R. Mouse genetic models for prepulse inhibition: an early review. Mol Psychiatry. 2002; 7(10):1039-53. PMID: 12476318.
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      241. Ludewig S, Ludewig K, Geyer M, Hell D, Vollenweider FX. Prepulse inhibition deficits in patients with panic disorder. Depress Anxiety. 2002; 15(2):55-60. PMID: 11891993.
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      242. Vollenweider FX, Geyer M. A systems model of altered consciousness: integrating natural and drug-induced psychoses. Brain Res Bull. 2001 Nov 15; 56(5):495-507. PMID: 11750795.
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      243. Swerdlow NR, Karban B, Ploum Y, Sharp R, Geyer M, Eastvold A. Tactile prepuff inhibition of startle in children with Tourette's syndrome: in search of an "fMRI-friendly" startle paradigm. Biol Psychiatry. 2001 Oct 15; 50(8):578-85. PMID: 11690592.
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      244. Weiner DM, Burstein ES, Nash N, Croston GE, Currier EA, Vanover KE, Harvey SC, Donohue E, Hansen HC, Andersson CM, Spalding TA, Gibson DF, Krebs-Thomson K, Powell SB, Geyer M, Hacksell U, Brann MR. 5-hydroxytryptamine2A receptor inverse agonists as antipsychotics. J Pharmacol Exp Ther. 2001 Oct; 299(1):268-76. PMID: 11561089.
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      245. Nekrep N, Geyer M, Jabrane-Ferrat N, Peterlin BM. Analysis of ankyrin repeats reveals how a single point mutation in RFXANK results in bare lymphocyte syndrome. Mol Cell Biol. 2001 Aug; 21(16):5566-76. PMID: 11463838; PMCID: PMC87278.
      246. Geyer M, Krebs-Thomson K, Braff DL, Swerdlow NR. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl). 2001 Jul; 156(2-3):117-54. PMID: 11549216.
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      247. Swerdlow NR, Geyer M, Braff DL. Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl). 2001 Jul; 156(2-3):194-215. PMID: 11549223.
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      248. Geyer M, Fackler OT, Peterlin BM. Structure--function relationships in HIV-1 Nef. EMBO Rep. 2001 Jul; 2(7):580-5. PMID: 11463741; PMCID: PMC1083955.
      249. Braff DL, Geyer M, Swerdlow NR. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl). 2001 Jul; 156(2-3):234-58. PMID: 11549226.
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      250. Ralph RJ, Paulus MP, Geyer M. Strain-specific effects of amphetamine on prepulse inhibition and patterns of locomotor behavior in mice. J Pharmacol Exp Ther. 2001 Jul; 298(1):148-55. PMID: 11408536.
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      251. Geyer M, Peterlin BM. Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef. FEBS Lett. 2001 May 11; 496(2-3):91-5. PMID: 11356189.
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      252. Krebs-Thomson K, Giracello D, Solis A, Geyer M. Post-weaning handling attenuates isolation-rearing induced disruptions of prepulse inhibition in rats. Behav Brain Res. 2001 May; 120(2):221-4. PMID: 11182170.
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      253. Geyer M, Swerdlow NR. Measurement of startle response, prepulse inhibition, and habituation. Curr Protoc Neurosci. 2001 May; Chapter 8:Unit 8.7. PMID: 18428548.
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      254. Braff DL, Geyer M, Light GA, Sprock J, Perry W, Cadenhead KS, Swerdlow NR. Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res. 2001 Apr 15; 49(1-2):171-8. PMID: 11343875.
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      255. Liechti ME, Geyer M, Hell D, Vollenweider FX. Effects of MDMA (ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin. Neuropsychopharmacology. 2001 Mar; 24(3):240-52. PMID: 11166515.
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      256. Mandic R, Fackler OT, Geyer M, Linnemann T, Zheng YH, Peterlin BM. Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivity. Mol Biol Cell. 2001 Feb; 12(2):463-73. PMID: 11179428; PMCID: PMC30956.
      257. Dirks A, Pattij T, Bouwknecht JA, Westphal TT, Hijzen TH, Groenink L, van der Gugten J, Oosting RS, Hen R, Geyer M, Olivier B. 5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response. Behav Brain Res. 2001 Jan 29; 118(2):169-78. PMID: 11164514.
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      258. Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer M. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J Neurosci. 2001 Jan 01; 21(1):305-13. PMID: 11150348.
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      259. Bouwknecht JA, Hijzen TH, van der Gugten J, Dirks A, Maes RA, Hen R, Geyer M, Olivier B. Startle responses, heart rate, and temperature in 5-HT1B receptor knockout mice. Neuroreport. 2000 Dec 18; 11(18):4097-102. PMID: 11192635.
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      260. Farid M, Martinez ZA, Geyer M, Swerdlow NR. Regulation of sensorimotor gating of the startle reflex by serotonin 2A receptors. Ontogeny and strain differences. Neuropsychopharmacology. 2000 Dec; 23(6):623-32. PMID: 11063918.
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      261. Martinez ZA, Oostwegel J, Geyer M, Ellison GD, Swerdlow NR. "Early" and "late" effects of sustained haloperidol on apomorphine- and phencyclidine-induced sensorimotor gating deficits. Neuropsychopharmacology. 2000 Nov; 23(5):517-27. PMID: 11027917.
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      262. Dulawa SC, Geyer M. Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice. Neuropharmacology. 2000 Aug 23; 39(11):2170-9. PMID: 10963760.
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      263. Swerdlow NR, Martinez ZA, Hanlon FM, Platten A, Farid M, Auerbach P, Braff DL, Geyer M. Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists. J Neurosci. 2000 Jun 01; 20(11):4325-36. PMID: 10818168.
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      264. Swerdlow NR, Braff DL, Geyer M. Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon. Behav Pharmacol. 2000 Jun; 11(3-4):185-204. PMID: 11103873.
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      265. Dulawa SC, Gross C, Stark KL, Hen R, Geyer M. Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology. 2000 Jun; 22(6):650-9. PMID: 10788764.
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      266. Varty GB, Paulus MP, Braff DL, Geyer M. Environmental enrichment and isolation rearing in the rat: effects on locomotor behavior and startle response plasticity. Biol Psychiatry. 2000 May 15; 47(10):864-73. PMID: 10807959.
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      267. Light GA, Geyer M, Clementz BA, Cadenhead KS, Braff DL. Normal P50 suppression in schizophrenia patients treated with atypical antipsychotic medications. Am J Psychiatry. 2000 May; 157(5):767-71. PMID: 10784470.
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      268. Fackler OT, Lu X, Frost JA, Geyer M, Jiang B, Luo W, Abo A, Alberts AS, Peterlin BM. p21-activated kinase 1 plays a critical role in cellular activation by Nef. Mol Cell Biol. 2000 Apr; 20(7):2619-27. PMID: 10713183; PMCID: PMC85477.
      269. Dulawa SC, Scearce-Levie KA, Hen R, Geyer M. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology (Berl). 2000 Apr; 149(3):306-12. PMID: 10823412.
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      270. Palmer AA, Dulawa SC, Mottiwala AA, Conti LH, Geyer M, Printz MP. Prepulse startle deficit in the Brown Norway rat: a potential genetic model. Behav Neurosci. 2000 Apr; 114(2):374-88. PMID: 10832798.
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      271. Martinez ZA, Halim ND, Oostwegel JL, Geyer M, Swerdlow NR. Ontogeny of phencyclidine and apomorphine-induced startle gating deficits in rats. Pharmacol Biochem Behav. 2000 Mar; 65(3):449-57. PMID: 10683485.
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      272. Cadenhead KS, Light GA, Geyer M, Braff DL. Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder. Am J Psychiatry. 2000 Jan; 157(1):55-9. PMID: 10618013.
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      273. Taube R, Fujinaga K, Irwin D, Wimmer J, Geyer M, Peterlin BM. Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1. J Virol. 2000 Jan; 74(2):892-8. PMID: 10623752; PMCID: PMC111610.
      274. Paulus MP, Varty GB, Geyer M. The genetic liability to stress and postweaning isolation have a competitive influence on behavioral organization in rats. Physiol Behav. 2000 Jan; 68(3):389-94. PMID: 10716550.
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      275. Geyer M. Assessing prepulse inhibition of startle in wild-type and knockout mice. Psychopharmacology (Berl). 1999 Nov; 147(1):11-3. PMID: 10591857.
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      276. Dulawa SC, Grandy DK, Low MJ, Paulus MP, Geyer M. Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. J Neurosci. 1999 Nov 01; 19(21):9550-6. PMID: 10531457.
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      277. Light GA, Malaspina D, Geyer M, Luber BM, Coleman EA, Sackeim HA, Braff DL. Amphetamine disrupts P50 suppression in normal subjects. Biol Psychiatry. 1999 Oct 01; 46(7):990-6. PMID: 10509182.
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      278. Swerdlow NR, Geyer M, Hartman PL, Sprock J, Auerbach PP, Cadenhead K, Perry W, Braff DL. Sex differences in sensorimotor gating of the human startle reflex: all smoke? Psychopharmacology (Berl). 1999 Sep; 146(2):228-32. PMID: 10525760.
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      279. Bakshi VP, Geyer M. Ontogeny of isolation rearing-induced deficits in sensorimotor gating in rats. Physiol Behav. 1999 Sep; 67(3):385-92. PMID: 10497957.
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      280. Hessel A, Geyer M, Plöttner G, Brähler E. [The situation of young people in Germany--results of a representative population survey]. Prax Kinderpsychol Kinderpsychiatr. 1999 Sep; 48(7):465-80. PMID: 10520292.
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      281. Geyer M, Swerdlow NR, Lehmann-Masten V, Teschendorf HJ, Traut M, Gross G. Effects of LU-111995 in three models of disrupted prepulse inhibition in rats. J Pharmacol Exp Ther. 1999 Aug; 290(2):716-24. PMID: 10411583.
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      282. Martinez ZA, Ellison GD, Geyer M, Swerdlow NR. Effects of sustained phencyclidine exposure on sensorimotor gating of startle in rats. Neuropsychopharmacology. 1999 Jul; 21(1):28-39. PMID: 10379517.
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      283. Swerdlow NR, Braff DL, Geyer M. Cross-species studies of sensorimotor gating of the startle reflex. Ann N Y Acad Sci. 1999 Jun 29; 877:202-16. PMID: 10415651.
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      284. Fackler OT, Luo W, Geyer M, Alberts AS, Peterlin BM. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol Cell. 1999 Jun; 3(6):729-39. PMID: 10394361.
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      285. Ralph RJ, Varty GB, Kelly MA, Wang YM, Caron MG, Rubinstein M, Grandy DK, Low MJ, Geyer M. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. J Neurosci. 1999 Jun 01; 19(11):4627-33. PMID: 10341260.
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      286. Varty GB, Bakshi VP, Geyer M. M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats. Neuropsychopharmacology. 1999 Apr; 20(4):311-21. PMID: 10088132.
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      287. Braff DL, Swerdlow NR, Geyer M. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients. Am J Psychiatry. 1999 Apr; 156(4):596-602. PMID: 10200740.
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      288. Varty GB, Braff DL, Geyer M. Is there a critical developmental 'window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response? Behav Brain Res. 1999 Apr; 100(1-2):177-83. PMID: 10212065.
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      289. Vollenweider FX, Remensberger S, Hell D, Geyer M. Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans. Psychopharmacology (Berl). 1999 Apr; 143(4):365-72. PMID: 10367553.
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      290. Grailhe R, Waeber C, Dulawa SC, Hornung JP, Zhuang X, Brunner D, Geyer M, Hen R. Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron. 1999 Mar; 22(3):581-91. PMID: 10197537.
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      291. Martinez ZA, Ellison GD, Geyer M, Swerdlow NR. Effects of sustained cocaine exposure on sensorimotor gating of startle in rats. Psychopharmacology (Berl). 1999 Mar; 142(3):253-60. PMID: 10208317.
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      292. Perry W, Geyer M, Braff DL. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients. Arch Gen Psychiatry. 1999 Mar; 56(3):277-81. PMID: 10078506.
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      293. Bakshi VP, Tricklebank M, Neijt HC, Lehmann-Masten V, Geyer M. Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats. J Pharmacol Exp Ther. 1999 Feb; 288(2):643-52. PMID: 9918570.
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      294. Cadenhead KS, Carasso BS, Swerdlow NR, Geyer M, Braff DL. Prepulse inhibition and habituation of the startle response are stable neurobiological measures in a normal male population. Biol Psychiatry. 1999 Feb 01; 45(3):360-4. PMID: 10023514.
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      295. Paulus MP, Geyer M, Braff DL. Long-range correlations in choice sequences of schizophrenic patients. Schizophr Res. 1999 Jan 04; 35(1):69-75. PMID: 9988842.
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      296. Bakshi VP, Geyer M. Alpha-1-adrenergic receptors mediate sensorimotor gating deficits produced by intracerebral dizocilpine administration in rats. Neuroscience. 1999; 92(1):113-21. PMID: 10392835.
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      297. Dulawa SC, Hen R, Scearce-Levie K, Geyer M. 5-HT1B receptor modulation of prepulse inhibition: recent findings in wild-type and 5-HT1B knockout mice. Ann N Y Acad Sci. 1998 Dec 15; 861:79-84. PMID: 9928242.
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      298. Paulus MP, Geyer M, Sternberg E. Differential movement patterns but not amount of activity in unconditioned motor behavior of Fischer, Lewis, and Sprague-Dawley rats. Physiol Behav. 1998 Dec 01; 65(3):601-6. PMID: 9877429.
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      299. Clementz BA, Geyer M, Braff DL. Poor P50 suppression among schizophrenia patients and their first-degree biological relatives. Am J Psychiatry. 1998 Dec; 155(12):1691-4. PMID: 9842777.
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      300. Varty GB, Geyer M. Effects of isolation rearing on startle reactivity, habituation, and prepulse inhibition in male Lewis, Sprague-Dawley, and Fischer F344 rats. Behav Neurosci. 1998 Dec; 112(6):1450-7. PMID: 9926827.
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      301. Gouzoulis-Mayfrank E, Heekeren K, Thelen B, Lindenblatt H, Kovar KA, Sass H, Geyer M. Effects of the hallucinogen psilocybin on habituation and prepulse inhibition of the startle reflex in humans. Behav Pharmacol. 1998 Nov; 9(7):561-6. PMID: 9862081.
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      302. Krebs-Thomson K, Geyer M. Evidence for a functional interaction between 5-HT1A and 5-HT2 receptors in rats. Psychopharmacology (Berl). 1998 Nov; 140(1):69-74. PMID: 9862404.
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      303. Swerdlow NR, Bakshi V, Waikar M, Taaid N, Geyer M. Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats. Psychopharmacology (Berl). 1998 Nov; 140(1):75-80. PMID: 9862405.
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      304. Bakshi VP, Geyer M. Multiple limbic regions mediate the disruption of prepulse inhibition produced in rats by the noncompetitive NMDA antagonist dizocilpine. J Neurosci. 1998 Oct 15; 18(20):8394-401. PMID: 9763482.
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      305. McAinsh AM, Geyer M, Fandrey J, Rüegg JC, Wiesner RJ. Expression of vascular endothelial growth factor during the development of cardiac hypertrophy in spontaneously hypertensive rats. Mol Cell Biochem. 1998 Oct; 187(1-2):141-6. PMID: 9788751.
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      306. Swerdlow NR, Taaid N, Oostwegel JL, Randolph E, Geyer M. Towards a cross-species pharmacology of sensorimotor gating: effects of amantadine, bromocriptine, pergolide and ropinirole on prepulse inhibition of acoustic startle in rats. Behav Pharmacol. 1998 Sep; 9(5-6):389-96. PMID: 9832924.
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      307. Paulus MP, Bakshi VP, Geyer M. Isolation rearing affects sequential organization of motor behavior in post-pubertal but not pre-pubertal Lister and Sprague-Dawley rats. Behav Brain Res. 1998 Aug; 94(2):271-80. PMID: 9722278.
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      308. Geyer M. Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research. Pharmacopsychiatry. 1998 Jul; 31 Suppl 2:73-9. PMID: 9754837.
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      309. Cierpka M, Strack M, Benninghoven D, Staats H, Dahlbender R, Pokorny D, Frevert G, Blaser G, Kächele H, Geyer M, Körner A, Albani C. Stereotypical relationship patterns and psychopathology. Psychother Psychosom. 1998 Jul-Oct; 67(4-5):241-8. PMID: 9693351.
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      310. Varty GB, Hauger RL, Geyer M. Aging effects on the startle response and startle plasticity in Fischer F344 rats. Neurobiol Aging. 1998 May-Jun; 19(3):243-51. PMID: 9661999.
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      311. Krebs-Thomson K, Paulus MP, Geyer M. Effects of hallucinogens on locomotor and investigatory activity and patterns: influence of 5-HT2A and 5-HT2C receptors. Neuropsychopharmacology. 1998 May; 18(5):339-51. PMID: 9536447.
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      312. Bakshi VP, Swerdlow NR, Braff DL, Geyer M. Reversal of isolation rearing-induced deficits in prepulse inhibition by Seroquel and olanzapine. Biol Psychiatry. 1998 Mar 15; 43(6):436-45. PMID: 9532349.
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      313. Clementz BA, Geyer M, Braff DL. Multiple site evaluation of P50 suppression among schizophrenia and normal comparison subjects. Schizophr Res. 1998 Feb 27; 30(1):71-80. PMID: 9542790.
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      314. Krebs-Thomson K, Lehmann-Masten V, Naiem S, Paulus MP, Geyer M. Modulation of phencyclidine-induced changes in locomotor activity and patterns in rats by serotonin. Eur J Pharmacol. 1998 Feb 19; 343(2-3):135-43. PMID: 9570460.
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      315. Druhan JP, Geyer M, Valentino RJ. Lack of sensitization to the effects of d-amphetamine and apomorphine on sensorimotor gating in rats. Psychopharmacology (Berl). 1998 Feb; 135(3):296-304. PMID: 9498734.
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      316. Swerdlow NR, Varty GB, Geyer M. Discrepant findings of clozapine effects on prepulse inhibition of startle: is it the route or the rat? Neuropsychopharmacology. 1998 Jan; 18(1):50-6. PMID: 9408918.
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      317. Swerdlow NR, Geyer M. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull. 1998; 24(2):285-301. PMID: 9613626.
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      318. Carasso BS, Bakshi VP, Geyer M. Disruption in prepulse inhibition after alpha-1 adrenoceptor stimulation in rats. Neuropharmacology. 1998; 37(3):401-4. PMID: 9681939.
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      319. Abel K, Waikar M, Pedro B, Hemsley D, Geyer M. Repeated testing of prepulse inhibition and habituation of the startle reflex: a study in healthy human controls. J Psychopharmacol. 1998; 12(4):330-7. PMID: 10065906.
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      320. Cadenhead KS, Geyer M, Butler RW, Perry W, Sprock J, Braff DL. Information processing deficits of schizophrenia patients: relationship to clinical ratings, gender and medication status. Schizophr Res. 1997 Nov 07; 28(1):51-62. PMID: 9428064.
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      321. Bakshi VP, Geyer M. Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alpha-1 noradrenergic antagonist. J Pharmacol Exp Ther. 1997 Nov; 283(2):666-74. PMID: 9353384.
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      322. Dulawa SC, Hen R, Scearce-Levie K, Geyer M. Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology (Berl). 1997 Jul; 132(2):125-34. PMID: 9266609.
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      323. Sipes TE, Geyer M. DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum. Brain Res. 1997 Jun 27; 761(1):97-104. PMID: 9247071.
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      324. Clementz BA, Geyer M, Braff DL. P50 suppression among schizophrenia and normal comparison subjects: a methodological analysis. Biol Psychiatry. 1997 May 15; 41(10):1035-44. PMID: 9129784.
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      325. Martinez DL, Geyer M. Characterization of the disruptions of prepulse inhibition and habituation of startle induced by alpha-ethyltryptamine. Neuropsychopharmacology. 1997 Mar; 16(3):246-55. PMID: 9138441.
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      326. Swerdlow NR, Bakshi V, Geyer M. Seroquel restores sensorimotor gating in phencyclidine-treated rats. J Pharmacol Exp Ther. 1996 Dec; 279(3):1290-9. PMID: 8968353.
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      327. Schweins T, Geyer M, Kalbitzer HR, Wittinghofer A, Warshel A. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras. Biochemistry. 1996 Nov 12; 35(45):14225-31. PMID: 8916907.
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      328. Krebs-Thomson K, Geyer M. The role of 5-HT(1A) receptors in the locomotor-suppressant effects of LSD: WAY-100635 studies of 8-OH-DPAT, DOI and LSD in rats. Behav Pharmacol. 1996 Nov; 7(6):551-559. PMID: 11224452.
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      329. Raditsch M, Geyer M, Kalbitzer HR, Jahn W, Ruppersberg JP, Witzemann V. Polyamine spider toxins and mammalian N-methyl-D-aspartate receptors. Structural basis for channel blocking and binding of argiotoxin636. Eur J Biochem. 1996 Sep 01; 240(2):416-26. PMID: 8841407.
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      330. Sipes TE, Geyer M. Functional behavioral homology between rat 5-HT1B and guinea pig 5-HT1D receptors in the modulation of prepulse inhibition of startle. Psychopharmacology (Berl). 1996 Jun; 125(3):231-7. PMID: 8815958.
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      331. Swerdlow NR, Braff DL, Hartston H, Perry W, Geyer M. Latent inhibition in schizophrenia. Schizophr Res. 1996 May; 20(1-2):91-103. PMID: 8794497.
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      332. Paulus MP, Geyer M, Braff DL. Use of methods from chaos theory to quantify a fundamental dysfunction in the behavioral organization of schizophrenic patients. Am J Psychiatry. 1996 May; 153(5):714-7. PMID: 8615422.
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      333. Humby T, Wilkinson LS, Robbins TW, Geyer M. Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat. J Neurosci. 1996 Mar 15; 16(6):2149-56. PMID: 8604058.
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      334. Dulawa SC, Geyer M. Psychopharmacology of prepulse inhibition in mice. Chin J Physiol. 1996; 39(3):139-46. PMID: 8955560.
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      335. Geyer M. Serotonergic functions in arousal and motor activity. Behav Brain Res. 1996; 73(1-2):31-5. PMID: 8788473.
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      336. Sipes TE, Geyer M. DOI disruption of prepulse inhibition of startle in the rat is mediated by 5-HT(2A) and not by 5-HT(2C) receptors. Behav Pharmacol. 1995 Dec; 6(8):839-842. PMID: 11224388.
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      337. Bakshi VP, Geyer M, Taaid N, Swerdlow NR. A comparison of the effects of amphetamine, strychnine and caffeine on prepulse inhibition and latent inhibition. Behav Pharmacol. 1995 Dec; 6(8):801-809. PMID: 11224383.
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      338. Bakshi VP, Geyer M. Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine. Psychopharmacology (Berl). 1995 Nov; 122(2):198-201. PMID: 8848537.
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      339. Swerdlow NR, Lipska BK, Weinberger DR, Braff DL, Jaskiw GE, Geyer M. Increased sensitivity to the sensorimotor gating-disruptive effects of apomorphine after lesions of medial prefrontal cortex or ventral hippocampus in adult rats. Psychopharmacology (Berl). 1995 Nov; 122(1):27-34. PMID: 8711061.
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      340. Lipska BK, Swerdlow NR, Geyer M, Jaskiw GE, Braff DL, Weinberger DR. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology (Berl). 1995 Nov; 122(1):35-43. PMID: 8711062.
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      341. Ellenbroek BA, Geyer M, Cools AR. The behavior of APO-SUS rats in animal models with construct validity for schizophrenia. J Neurosci. 1995 Nov; 15(11):7604-11. PMID: 7472511.
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      342. Rathner G, Túry F, Szabó P, Geyer M, Rumpold G, Forgács A, Söllner W, Plöttner G. Prevalence of eating disorders and minor psychiatric morbidity in central Europe before the political changes in 1989: a cross-cultural study. Psychol Med. 1995 Sep; 25(5):1027-35. PMID: 8588000.
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      343. Wan FJ, Geyer M, Swerdlow NR. Presynaptic dopamine-glutamate interactions in the nucleus accumbens regulate sensorimotor gating. Psychopharmacology (Berl). 1995 Aug; 120(4):433-41. PMID: 8539324.
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      344. Swerdlow NR, Geyer M, Perry W, Cadenhead K, Braff DL. Drug screening in "normal" controls. Biol Psychiatry. 1995 Jul 15; 38(2):123-4. PMID: 7578645.
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      345. Caine SB, Geyer M, Swerdlow NR. Effects of D3/D2 dopamine receptor agonists and antagonists on prepulse inhibition of acoustic startle in the rat. Neuropsychopharmacology. 1995 Apr; 12(2):139-45. PMID: 7779242.
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      346. Swerdlow NR, Filion D, Geyer M, Braff DL. "Normal" personality correlates of sensorimotor, cognitive, and visuospatial gating. Biol Psychiatry. 1995 Mar 01; 37(5):286-99. PMID: 7748980.
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      347. Swerdlow NR, Paulsen J, Braff DL, Butters N, Geyer M, Swenson MR. Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J Neurol Neurosurg Psychiatry. 1995 Feb; 58(2):192-200. PMID: 7876851; PMCID: PMC1073317.
      348. Sipes TA, Geyer M. 8-OH-DPAT disruption of prepulse inhibition in rats: reversal with (+)WAY 100,135 and localization of site of action. Psychopharmacology (Berl). 1995 Jan; 117(1):41-8. PMID: 7724701.
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      349. Braff DL, Swerdlow NR, Geyer M. Gating and habituation deficits in the schizophrenia disorders. Clin Neurosci. 1995; 3(2):131-9. PMID: 7583619.
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      350. Bakshi VP, Swerdlow NR, Geyer M. Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response. J Pharmacol Exp Ther. 1994 Nov; 271(2):787-94. PMID: 7965797.
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      351. Paulus MP, Geyer M, Braff DL. The assessment of sequential response organization in schizophrenic and control subjects. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Nov; 18(7):1169-85. PMID: 7846287.
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      352. Wan FJ, Geyer M, Swerdlow NR. Accumbens D2 modulation of sensorimotor gating in rats: assessing anatomical localization. Pharmacol Biochem Behav. 1994 Sep; 49(1):155-63. PMID: 7816867.
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      353. Sipes TA, Geyer M. Multiple serotonin receptor subtypes modulate prepulse inhibition of the startle response in rats. Neuropharmacology. 1994 Mar-Apr; 33(3-4):441-8. PMID: 7984282.
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      354. Wilkinson LS, Killcross SS, Humby T, Hall FS, Geyer M, Robbins TW. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology. 1994 Feb; 10(1):61-72. PMID: 8179795.
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      355. Swerdlow NR, Braff DL, Taaid N, Geyer M. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry. 1994 Feb; 51(2):139-54. PMID: 8297213.
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      356. Geyer M, Krebs KM. Serotonin receptor involvement in an animal model of the acute effects of hallucinogens. NIDA Res Monogr. 1994; 146:124-56. PMID: 8742797.
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      357. Krebs KM, Geyer M. Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats. Psychopharmacology (Berl). 1994 Jan; 113(3-4):429-37. PMID: 7862855.
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      358. Cadenhead KS, Geyer M, Braff DL. Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am J Psychiatry. 1993 Dec; 150(12):1862-7. PMID: 8238643.
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      359. Geyer M, Wilkinson LS, Humby T, Robbins TW. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol Psychiatry. 1993 Sep 15; 34(6):361-72. PMID: 8218603.
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      360. Swerdlow NR, Auerbach P, Monroe SM, Hartston H, Geyer M, Braff DL. Men are more inhibited than women by weak prepulses. Biol Psychiatry. 1993 Aug 15; 34(4):253-60. PMID: 8399822.
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      361. Geyer M, Bergmann C, Siebert WE. [Overuse syndrome in ballet: study of the effect of a tape bandage of the upper ankle joint with motion analysis]. Sportverletz Sportschaden. 1993 Jun; 7(2):78-83. PMID: 8351640.
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      362. Rempel NL, Callaway CW, Geyer M. Serotonin1B receptor activation mimics behavioral effects of presynaptic serotonin release. Neuropsychopharmacology. 1993 May; 8(3):201-11. PMID: 8099482.
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      363. Swerdlow NR, Geyer M. Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia. Pharmacol Biochem Behav. 1993 Mar; 44(3):741-4. PMID: 8451276.
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      364. Paulus MP, Geyer M. Three independent factors characterize spontaneous rat motor activity. Behav Brain Res. 1993 Feb 26; 53(1-2):11-20. PMID: 8466655.
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      365. Swerdlow NR, Benbow CH, Zisook S, Geyer M, Braff DL. A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder. Biol Psychiatry. 1993 Feb 15; 33(4):298-301. PMID: 8471686.
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      366. Swerdlow NR, Geyer M. Prepulse inhibition of acoustic startle in rats after lesions of the pedunculopontine tegmental nucleus. Behav Neurosci. 1993 Feb; 107(1):104-17. PMID: 8447948.
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      367. Paulus MP, Geyer M. Quantitative assessment of the microstructure of rat behavior: I, f(d), the extension of the scaling hypothesis. Psychopharmacology (Berl). 1993; 113(2):177-86. PMID: 7855179.
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      368. Paulus MP, Callaway CW, Geyer M. Quantitative assessment of the microstructure of rat behavior: II. Distinctive effects of dopamine releasers and uptake inhibitors. Psychopharmacology (Berl). 1993; 113(2):187-98. PMID: 7855180.
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      369. Krebs KM, Geyer M. Behavioral characterization of alpha-ethyltryptamine, a tryptamine derivative with MDMA-like properties in rats. Psychopharmacology (Berl). 1993; 113(2):284-7. PMID: 7855195.
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      370. Callaway CW, Wing LL, Nichols DE, Geyer M. Suppression of behavioral activity by norfenfluramine and related drugs in rats is not mediated by serotonin release. Psychopharmacology (Berl). 1993; 111(2):169-78. PMID: 7870948.
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      371. Caine SB, Geyer M, Swerdlow NR. Hippocampal modulation of acoustic startle and prepulse inhibition in the rat. Pharmacol Biochem Behav. 1992 Dec; 43(4):1201-8. PMID: 1475305.
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      372. Glowa JR, Geyer M, Gold PW, Sternberg EM. Differential startle amplitude and corticosterone response in rats. Neuroendocrinology. 1992 Nov; 56(5):719-23. PMID: 1488104.
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      373. Callaway CW, Geyer M. Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist. J Pharmacol Exp Ther. 1992 Oct; 263(1):318-26. PMID: 1357158.
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      374. Callaway CW, Rempel N, Peng RY, Geyer M. Serotonin 5-HT1-like receptors mediate hyperactivity in rats induced by 3,4-methylenedioxymethamphetamine. Neuropsychopharmacology. 1992 Sep; 7(2):113-27. PMID: 1358088.
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      375. Paulus MP, Geyer M. The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity. Neuropsychopharmacology. 1992 Aug; 7(1):15-31. PMID: 1355968.
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      376. Callaway CW, Geyer M. Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat. Eur J Pharmacol. 1992 Apr 07; 214(1):45-51. PMID: 1349861.
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      377. Braff DL, Grillon C, Geyer M. Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry. 1992 Mar; 49(3):206-15. PMID: 1567275.
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      378. Geyer M, Paulus MP. Multivariate and nonlinear approaches to characterizing drug effects on the locomotor and investigatory behavior of rats. NIDA Res Monogr. 1992; 124:203-35. PMID: 1470213.
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      379. Swerdlow NR, Caine SB, Geyer M. Regionally selective effects of intracerebral dopamine infusion on sensorimotor gating of the startle reflex in rats. Psychopharmacology (Berl). 1992; 108(1-2):189-95. PMID: 1410139.
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      380. Rassnick S, Koob GF, Geyer M. Responding to acoustic startle during chronic ethanol intoxication and withdrawal. Psychopharmacology (Berl). 1992; 106(3):351-8. PMID: 1570382.
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      381. Swerdlow NR, Caine SB, Braff DL, Geyer M. The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications. J Psychopharmacol. 1992 Jan; 6(2):176-90. PMID: 22291349.
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      382. Geyer M. Psychopharmacological models related to schizophrenia. J Psychopharmacol. 1992 Jan; 6(4):550-2. PMID: 22291414.
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      383. Kalbitzer HR, Maeda K, Rösch A, Maéda Y, Geyer M, Beneicke W, Neidig KP, Wittinghofer A. C-terminal structure and mobility of rabbit skeletal muscle light meromyosin as studied by one- and two-dimensional 1H NMR spectroscopy and X-ray small-angle scattering. Biochemistry. 1991 Aug 13; 30(32):8083-91. PMID: 1868084.
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      384. Lehmann-Masten VD, Geyer M. Spatial and temporal patterning distinguishes the locomotor activating effects of dizocilpine and phencyclidine in rats. Neuropharmacology. 1991 Jun; 30(6):629-36. PMID: 1922682.
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      385. Swerdlow NR, Keith VA, Braff DL, Geyer M. Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat. J Pharmacol Exp Ther. 1991 Feb; 256(2):530-6. PMID: 1825226.
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      386. Paulus MP, Geyer M. A temporal and spatial scaling hypothesis for the behavioral effects of psychostimulants. Psychopharmacology (Berl). 1991; 104(1):6-16. PMID: 1679242.
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      387. Paulus MP, Geyer M. A scaling approach to find order parameters quantifying the effects of dopaminergic agents on unconditioned motor activity in rats. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(6):903-19. PMID: 1684875.
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      388. Mittman SM, Geyer M. Dissociation of multiple effects of acute LSD on exploratory behavior in rats by ritanserin and propranolol. Psychopharmacology (Berl). 1991; 105(1):69-76. PMID: 1745714.
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      389. Mansbach RS, Geyer M. Parametric determinants in pre-stimulus modification of acoustic startle: interaction with ketamine. Psychopharmacology (Berl). 1991; 105(2):162-8. PMID: 1796122.
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      390. Callaway CW, Johnson MP, Gold LH, Nichols DE, Geyer M. Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists. Psychopharmacology (Berl). 1991; 104(3):293-301. PMID: 1924637.
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      391. Caine SB, Geyer M, Swerdlow NR. Carbachol infusion into the dentate gyrus disrupts sensorimotor gating of startle in the rat. Psychopharmacology (Berl). 1991; 105(3):347-54. PMID: 1798831.
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      392. Swerdlow NR, Caine SB, Geyer M. Opiate-dopamine interactions in the neural substrates of acoustic startle gating in the rat. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(3):415-26. PMID: 1862221.
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      393. Geyer M. Multiple serotonergic influences on startle responding. J Psychopharmacol. 1991 Jan; 5(4):334-5. PMID: 22282836.
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      394. Swerdlow NR, Braff DL, Geyer M. GABAergic projection from nucleus accumbens to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats. Brain Res. 1990 Nov 05; 532(1-2):146-50. PMID: 2282510.
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      395. Butler RW, Braff DL, Rausch JL, Jenkins MA, Sprock J, Geyer M. Physiological evidence of exaggerated startle response in a subgroup of Vietnam veterans with combat-related PTSD. Am J Psychiatry. 1990 Oct; 147(10):1308-12. PMID: 2399998.
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      396. Geyer M, Swerdlow NR, Mansbach RS, Braff DL. Startle response models of sensorimotor gating and habituation deficits in schizophrenia. Brain Res Bull. 1990 Sep; 25(3):485-98. PMID: 2292046.
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      397. Kim S, Scheerer S, Geyer M, Howell SB. Direct cerebrospinal fluid delivery of an antiretroviral agent using multivesicular liposomes. J Infect Dis. 1990 Sep; 162(3):750-2. PMID: 2167343.
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      398. Callaway CW, Wing LL, Geyer M. Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats. J Pharmacol Exp Ther. 1990 Aug; 254(2):456-64. PMID: 1974635.
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      399. Peng RY, Mansbach RS, Braff DL, Geyer M. A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia. Neuropsychopharmacology. 1990 Jun; 3(3):211-8. PMID: 2141986.
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      400. Braff DL, Geyer M. Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry. 1990 Feb; 47(2):181-8. PMID: 2405807.
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      401. Grillon C, Courchesne E, Ameli R, Geyer M, Braff DL. Increased distractibility in schizophrenic patients. Electrophysiologic and behavioral evidence. Arch Gen Psychiatry. 1990 Feb; 47(2):171-9. PMID: 2302027.
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      402. Swerdlow NR, Mansbach RS, Geyer M, Pulvirenti L, Koob GF, Braff DL. Amphetamine disruption of prepulse inhibition of acoustic startle is reversed by depletion of mesolimbic dopamine. Psychopharmacology (Berl). 1990; 100(3):413-6. PMID: 2315438.
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      403. Wing LL, Tapson GS, Geyer M. 5HT-2 mediation of acute behavioral effects of hallucinogens in rats. Psychopharmacology (Berl). 1990; 100(3):417-25. PMID: 2138338.
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      404. Swerdlow NR, Braff DL, Masten VL, Geyer M. Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens. Psychopharmacology (Berl). 1990; 101(3):414-20. PMID: 2114026.
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      405. Davis M, Mansbach RS, Swerdlow NR, Campeau S, Braff DL, Geyer M. Apomorphine disrupts the inhibition of acoustic startle induced by weak prepulses in rats. Psychopharmacology (Berl). 1990; 102(1):1-4. PMID: 2392496.
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      406. Paulus MP, Geyer M, Gold LH, Mandell AJ. Application of entropy measures derived from the ergodic theory of dynamical systems to rat locomotor behavior. Proc Natl Acad Sci U S A. 1990 Jan; 87(2):723-7. PMID: 1967830; PMCID: PMC53338.
      407. Mansbach RS, Geyer M. Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat. Neuropsychopharmacology. 1989 Dec; 2(4):299-308. PMID: 2692589.
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      408. Mansbach RS, Braff DL, Geyer M. Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat. Eur J Pharmacol. 1989 Aug 11; 167(1):49-55. PMID: 2776841.
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      409. Mittman SM, Geyer M. Effects of 5HT-1A agonists on locomotor and investigatory behaviors in rats differ from those of hallucinogens. Psychopharmacology (Berl). 1989; 98(3):321-9. PMID: 2501811.
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      410. Geyer M, Masten VL. Increases in diversive exploration in rats during hippocampal microinfusions of isoproterenol but not methoxamine. Physiol Behav. 1989 Jan; 45(1):213-7. PMID: 2543005.
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      411. Gold LH, Geyer M, Koob GF. Psychostimulant properties of MDMA. NIDA Res Monogr. 1989; 95:345-6. PMID: 2577038.
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      412. Gold LH, Geyer M, Koob GF. Neurochemical mechanisms involved in behavioral effects of amphetamines and related designer drugs. NIDA Res Monogr. 1989; 94:101-26. PMID: 2514360.
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      413. Gold LH, Koob GF, Geyer M. Spatial pattern analysis reveals similarities between amphetamine conditioned and unconditioned locomotion. Behav Pharmacol. 1989; 1(3):209-220. PMID: 11224032.
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      414. Mansbach RS, Geyer M. Blockade of potentiated startle responding in rats by 5-hydroxytryptamine1A receptor ligands. Eur J Pharmacol. 1988 Nov 08; 156(3):375-83. PMID: 2975225.
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      415. Gold LH, Koob GF, Geyer M. Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats. J Pharmacol Exp Ther. 1988 Nov; 247(2):547-55. PMID: 2903234.
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      416. Geyer M, Frampton SF. Peripheral mediation of effects of clenbuterol on locomotor and investigatory behavior in rats. Pharmacol Biochem Behav. 1988 Jun; 30(2):417-20. PMID: 2845445.
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      417. Geyer M, Tapson GS. Habituation of tactile startle is altered by drugs acting on serotonin-2 receptors. Neuropsychopharmacology. 1988 May; 1(2):135-47. PMID: 3150805.
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      418. Braff DL, Geyer M. Habituation deficits, serotonergic function, and schizophrenia: new animal model data. Psychopharmacol Bull. 1988; 24(3):426-30. PMID: 3153503.
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      419. Mansbach RS, Geyer M, Braff DL. Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology (Berl). 1988; 94(4):507-14. PMID: 3131796.
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      420. Geyer M, Russo PV, Segal DS, Kuczenski R. Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats. Pharmacol Biochem Behav. 1987 Nov; 28(3):393-9. PMID: 3685075.
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      421. Kim S, Kim DJ, Geyer M, Howell SB. Multivesicular liposomes containing 1-beta-D-arabinofuranosylcytosine for slow-release intrathecal therapy. Cancer Res. 1987 Aug 01; 47(15):3935-7. PMID: 3607740.
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      422. Lee EH, Wang FB, Tang YP, Geyer M. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain Res Bull. 1987 Mar; 18(3):345-53. PMID: 2438015.
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      423. Geyer M, Braff DL. Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr Bull. 1987; 13(4):643-68. PMID: 3438708.
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      424. Gately PF, Segal DS, Geyer M. Sequential changes in behavior induced by continuous infusions of amphetamine in rats. Psychopharmacology (Berl). 1987; 91(2):217-20. PMID: 3107035.
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      425. Edery H, Geyer M, Taylor P, Berman HA. Target sites for anticholinesterases on the ventral surface of the medulla oblongata: hypotension elicited by organophosphorus agents. J Auton Pharmacol. 1986 Sep; 6(3):195-205. PMID: 3771592.
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      426. Geyer M, Masten VL, Segal DS. Behavioral effects of xylamine-induced depletions of brain norepinephrine: interaction with amphetamine. Behav Brain Res. 1986 Jul; 21(1):55-64. PMID: 3741596.
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      427. Geyer M, Russo PV, Masten VL. Multivariate assessment of locomotor behavior: pharmacological and behavioral analyses. Pharmacol Biochem Behav. 1986 Jul; 25(1):277-88. PMID: 2875472.
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      428. Swerdlow NR, Braff DL, Geyer M, Koob GF. Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics. Biol Psychiatry. 1986 Jan; 21(1):23-33. PMID: 3080033.
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      429. Swerdlow NR, Geyer M, Vale WW, Koob GF. Corticotropin-releasing factor potentiates acoustic startle in rats: blockade by chlordiazepoxide. Psychopharmacology (Berl). 1986; 88(2):147-52. PMID: 3081925.
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      430. Gately PF, Segal DS, Geyer M. The behavioral effects of depletions of brain serotonin induced by 5,7-dihydroxytryptamine vary with time after administration. Behav Neural Biol. 1986 Jan; 45(1):31-42. PMID: 3954713.
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      431. Rettig R, Geyer M, Printz MP. Cardiovascular concomitants of tactile and acoustic startle responses in spontaneously hypertensive and normotensive rats. Physiol Behav. 1986; 36(6):1123-8. PMID: 3725916.
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      432. Buelke-Sam J, Kimmel CA, Adams J, Nelson CJ, Vorhees CV, Wright DC, St Omer V, Korol BA, Butcher RE, Geyer M. Collaborative Behavioral Teratology Study: results. Neurobehav Toxicol Teratol. 1985 Nov-Dec; 7(6):591-624. PMID: 3835454.
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      433. Geyer M, Reiter LW. Strategies for the selection of test methods. Neurobehav Toxicol Teratol. 1985 Nov-Dec; 7(6):661-2. PMID: 3835462.
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      434. Geyer M, Butcher RE, Fite K. A study of startle and locomotor activity in rats exposed prenatally to methylmercury. Neurobehav Toxicol Teratol. 1985 Nov-Dec; 7(6):759-65. PMID: 3835478.
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      435. Adams LM, Geyer M. A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats. Behav Neurosci. 1985 Oct; 99(5):881-900. PMID: 3843306.
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      436. Geyer M, Gordon J, Adams LM. Behavioral effects of xylamine-induced depletions of brain norepinephrine: interaction with LSD. Pharmacol Biochem Behav. 1985 Oct; 23(4):619-25. PMID: 3877938.
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      437. Adams LM, Geyer M. Patterns of exploration in rats distinguish lisuride from lysergic acid diethylamide. Pharmacol Biochem Behav. 1985 Sep; 23(3):461-8. PMID: 4048241.
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      438. Adams LM, Geyer M. Effects of DOM and DMT in a proposed animal model of hallucinogenic activity. Prog Neuropsychopharmacol Biol Psychiatry. 1985; 9(2):121-32. PMID: 3858911.
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      439. Gately PF, Poon SL, Segal DS, Geyer M. Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats. Psychopharmacology (Berl). 1985; 87(4):400-5. PMID: 3936096.
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      440. Geyer M, Lee EH. Effects of clonidine, piperoxane and locus coeruleus lesion on the serotonergic and dopaminergic systems in raphe and caudate nucleus. Biochem Pharmacol. 1984 Nov 01; 33(21):3399-404. PMID: 6437408.
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      441. Lee EH, Geyer M. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacol Biochem Behav. 1984 Aug; 21(2):301-11. PMID: 6207549.
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      442. Geyer M, Gordon J, Adams LM. Depletions of central norepinephrine by intraventricular xylamine in rats. Eur J Pharmacol. 1984 Apr 20; 100(2):227-31. PMID: 6203760.
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      443. Geyer M, Segal DS, Greenberg BD. Increased startle responding in rats treated with phencyclidine. Neurobehav Toxicol Teratol. 1984 Mar-Apr; 6(2):161-4. PMID: 6472561.
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      444. Lee EH, Geyer M. Indirect effects of apomorphine on serotoninergic neurons in rats. Neuroscience. 1984 Feb; 11(2):437-42. PMID: 6201781.
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      445. Lee EH, Geyer M. Similarities of the effects of apomorphine and 3-PPP on serotonin neurons. Eur J Pharmacol. 1983 Oct 28; 94(3-4):297-303. PMID: 6653663.
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      446. Zheng S, Berman HA, Geyer M. Behavior during hippocampal microinfusions: anticholinesterase-induced locomotor activation. Behav Brain Res. 1983 Sep; 9(3):295-304. PMID: 6639738.
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      447. Lee EH, Geyer M. Selective effects of apomorphine on dorsal raphe neurons: a cytofluorimetric study. Brain Res Bull. 1982 Jul-Dec; 9(1-6):719-25. PMID: 6184135.
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      448. Geyer M, Flicker CE, Lee EH. Effects of tactile startle on serotonin content of midbrain raphe neurons in rats. Behav Brain Res. 1982 Apr; 4(4):369-76. PMID: 7073886.
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      449. Flicker C, Geyer M. The hippocampus as a possible site of action for increased locomotion during intracerebral infusions of norepinephrine. Behav Neural Biol. 1982 Apr; 34(4):421-6. PMID: 7126090.
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      450. Flicker C, Geyer M. Behavior during hippocampal microinfusions. III. Lidocaine versus picrotoxin. Brain Res. 1982 Mar; 257(1):129-36. PMID: 7199365.
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      451. Flicker C, Geyer M. Behavior during hippocampal microinfusions. II. Muscarinic locomotor activation. Brain Res. 1982 Mar; 257(1):105-27. PMID: 7059844.
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      452. Flicker C, Geyer M. Behavior during hippocampal microinfusions. IV. Transmitter interactions. Brain Res. 1982 Mar; 257(1):137-47. PMID: 6120751.
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      453. Flicker C, Geyer M. Behavior during hippocampal microinfusions. I. Norepinephrine and diversive exploration. Brain Res. 1982 Mar; 257(1):79-103. PMID: 6277439.
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      454. Adams LM, Geyer M. LSD-induced alterations of locomotor patterns and exploration in rats. Psychopharmacology (Berl). 1982; 77(2):179-85. PMID: 6812137.
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      455. Geyer M, Braff DL. Habituation of the Blink reflex in normals and schizophrenic patients. Psychophysiology. 1982 Jan; 19(1):1-6. PMID: 7058230.
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      456. Ward HW, Pollare T, Geyer M. Effects of caffeine on tactile startle in rats. Pharmacol Biochem Behav. 1981 Dec; 15(6):875-7. PMID: 7323112.
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      457. Geyer M. Effects of levonantradol on habituation of startle in rats. J Clin Pharmacol. 1981 Aug-Sep; 21(8-9 Suppl):235S-239S. PMID: 7298869.
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      458. Segal DS, Geyer M, Schuckit MA. Stimulant-induced psychosis: an evaluation of animal methods. Essays Neurochem Neuropharmacol. 1981; 5:95-129. PMID: 6112147.
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      459. Adams LM, Geyer M. Effects of 6-hydroxydopamine lesions of locus coeruleus on startle in rats. Psychopharmacology (Berl). 1981; 73(4):394-8. PMID: 6789365.
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      460. Braff DL, Geyer M. Acute and chronic LSD effects on rat startle: data supporting an LSD--rat model of schizophrenia. Biol Psychiatry. 1980 Dec; 15(6):909-16. PMID: 7193055.
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      461. Geyer M, Petersen LR, Rose GJ. Effects of serotonergic lesions on investigatory responding by rats in a holeboard. Behav Neural Biol. 1980 Oct; 30(2):160-77. PMID: 7447870.
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      462. Lee EH, Geyer M. Persistent effects of chronic administration of LSD on intracellular serotonin content in rat midbrain. Neuropharmacology. 1980 Oct; 19(10):1005-7. PMID: 7422071.
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      463. Warbritton JD, Geyer M, Jeppsson B, Fischer JE. Decreased startle reactivity in the end-to-side portacaval shunted rat. Pharmacol Biochem Behav. 1980 May; 12(5):739-42. PMID: 7393968.
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      464. Geyer M. Both indoleamine and phenylethylamine hallucinogens increase serotonin in both dorsal and median raphe neurons. Life Sci. 1980 Feb 11; 26(6):431-4. PMID: 6768945.
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      465. Geyer M, Barthel E, Schröder F, Franke G, Küstner R. [Prognosis, chronification and therapeutic relations in unsatisfactorily improved secondary faulty developments with cardiovascular affections]. Psychiatr Neurol Med Psychol (Leipz). 1979 Nov; 31(11):681-8. PMID: 549043.
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      466. Geyer M, Light RK. LSD-induced alterations of investigatory responding in rats. Psychopharmacology (Berl). 1979 Sep; 65(1):41-7. PMID: 41281.
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      467. Geyer M, Light RK, Rose GJ, Petersen LR, Horwitt DD, Adams LM, Hawkins RL. A characteristic effect of hallucinogens on investigatory responding in rats. Psychopharmacology (Berl). 1979 Sep; 65(1):35-40. PMID: 116288.
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      468. Geyer M, Rose GJ, Petersen LR. Mescaline increases startle responding equally in normal and raphe-lesioned rats. Pharmacol Biochem Behav. 1979 Feb; 10(2):293-8. PMID: 450941.
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      469. Warbritton JD, Geyer M, Jeppsson BW, Fischer JE. Behavioral model of early hepatic encephalopathy in rats. Surg Forum. 1979; 30:394-6. PMID: 538643.
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      470. Geyer M, Petersen LR, Rose GJ, Horwitt DD, Light RK, Adams LM, Zook JA, Hawkins RL, Mandell AJ. The effects of lysergic acid diethylamide and mescaline-derived hallucinogens on sensory-integrative function: tactile startle. J Pharmacol Exp Ther. 1978 Dec; 207(3):837-47. PMID: 731434.
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      471. Geyer M, Dawsey WJ, Mandell AJ. Fading: a new cytofluorimetric measure quantifying serotonin in the presence of catecholamines at the cellular level in brain. J Pharmacol Exp Ther. 1978 Nov; 207(2):650-67. PMID: 309507.
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      472. Braff D, Stone C, Callaway E, Geyer M, Glick I, Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology. 1978 Jul; 15(4):339-43. PMID: 693742.
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      473. Segal DS, Geyer M. Pre- and post-junctional supersensitivity: differentiation by intraventricular infusions of norepinephrine and methoxamine. Psychopharmacology (Berl). 1976 Nov 10; 50(2):145-8. PMID: 188061.
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      474. Scholle HC, Zwiener U, Geyer M, Goldammer D. [Psychophysiological studies in the framework of objective diagnosis of neuroses with factor and discrimination analyses]. Psychiatr Neurol Med Psychol (Leipz). 1976 May; 28(5):267-74. PMID: 940891.
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      475. Geyer M, Puerto A, Menkes DB, Segal DS, Mandell AJ. Behavioral studies following lesions of the mesolimbic and mesostriatal serotonergic pathways. Brain Res. 1976 Apr 23; 106(2):257-69. PMID: 1276871.
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      476. Geyer M, Puerto A, Dawsey WJ, Knapp S, Bullard WP, Mandell AJ. Histologic and enzymatic studies of the mesolimbic and mesostriatal serotonergic pathways. Brain Res. 1976 Apr 23; 106(2):241-56. PMID: 6112.
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      477. Hsu LL, Geyer M, Mandell AJ. Extrapineal amine N-acetylation in rat brain. Regional and subcellular distribution and enzyme kinetics. Biochem Pharmacol. 1976 Apr 01; 25(7):815-9. PMID: 938582.
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      478. Segal DS, Geyer M, Weiner BE. Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity. Science. 1975 Jul 25; 189(4199):301-3. PMID: 1145205.
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      479. Geyer M, Warbritton JD, Menkes DB, Zook JA, Mandell AJ. Opposite effects of intraventricular serotonin and bufotenin on rat startle responses. Pharmacol Biochem Behav. 1975 Jul-Aug; 3(4):687-91. PMID: 1187731.
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      480. Geyer M, Dawsey WJ, Mandell AJ. Differential effects of caffeine, D-amphetamine and methylphenidate on individual raphe cell fluorescence: a microspectrofluorimetric demonstration. Brain Res. 1975 Feb 21; 85(1):135-9. PMID: 1109692.
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      481. Geyer M. Functional heterogeneity within neurotransmitter systems. Psychopharmacol Commun. 1975; 1(6):675-85. PMID: 4862.
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      482. Geyer M, Kliem U, Voigtsberger P. [Psychosomatic aspects of cholelithiasis]. Psychiatr Neurol Med Psychol (Leipz). 1974 Aug; 26(8):457-65. PMID: 4449915.
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      483. Knapp S, Mandell AJ, Geyer M. Effects of amphetamines on regional tryptophan hydroxylase activity and synaptosomal conversion of tryptophan to 5-hydroxytryptamine in rat brain. J Pharmacol Exp Ther. 1974 Jun; 189(3):676-89. PMID: 4843167.
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      484. Geyer M, Segal DS. Shock-induced aggression: opposite effects of intraventricularly infused dopamine and norepinephrine. Behav Biol. 1974 Jan; 10(1):99-104. PMID: 4856062.
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      485. Segal DS, McAllister C, Geyer M. Ventricular infusion of norepinephrine and amphetamine: direct versus indirect action. Pharmacol Biochem Behav. 1974 Jan-Feb; 2(1):79-86. PMID: 4857225.
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      486. Korevaar WC, Geyer M, Knapp S, Hsu LL, Mandell AJ. Regional distribution of 5-methyltetrahydrofolic acid in brain. Nat New Biol. 1973 Oct 24; 245(147):244-5. PMID: 4518367.
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      487. Geyer M, Segal DS. Differential effects of reserpine and alpha-methyl-P-tyrosine on norepinephrine and dopamine induced behavioral activity. Psychopharmacologia. 1973 Mar 16; 29(2):131-40. PMID: 4709837.
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      488. Geyer M, Segal DS, Mandell AJ. Effect of intraventricular infusion of dopamine and norepinephrine on motor activity. Physiol Behav. 1972 Apr; 8(4):653-8. PMID: 5038135.
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      489. Van Orden LS, Burke JP, Geyer M, Lodoen FV. Localization of depletion-sensitive and depletion-resistant norepinephrine storage sites in autonomic ganglia. J Pharmacol Exp Ther. 1970 Jul; 174(1):56-71. PMID: 5424704.
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