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Mark Geyer

Title(s)Recall Faculty, Psychiatry
SchoolHealth Sciences
Address9500 Gilman Drive #0804
La Jolla CA 92093
Phone619-543-3582
ORCID ORCID Icon0000-0001-6137-9331 Additional info
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    Biography

    Mark A. Geyer Ph.D. is Distinguished Professor of Psychiatry and Neurosciences Emeritus at the University of California San Diego (UCSD) and directs the Neuropsychopharmacology Unit of the VISN 22 Veterans Administration Mental Illness Research, Clinical, and Education Center. Since receiving his doctorate in Psychology in 1972, he has focused on basic research addressing psychotic disorders and the related behavioral and neurobiological effects of psychedelics and other psychoactive drugs. For four decades, his group has had continuous funding from the National Institute on Drug Abuse to study the behavioral effects of psychedelics and entactogens. At UCSD, he is a founding member of the Consortium for Translational Research in Neuropsychopharmacology (CTRIN) and Translational Research in Psychophysiology, Exploration, and Cognition (TRIPEC) groups. In 1993, he co-founded the Heffter Research Institute, which pioneered and supported much of the scientific research that has prompted the exploration of psychedelics as potential therapeutics in humans. He has recently co-founded the Psychedelics and Health Research Initiative at UCSD, which is exploring the efficacy of psychedelics in the treatment of pain disorders. Dr. Geyer is respected internationally for his research on the psychophysiology, neurobiology, and pharmacotherapy of schizophrenia and bipolar disorder. He has published 470+ peer-reviewed papers and 50+ reviews, including many addressing the mechanisms subserving the effects of antipsychotics, psychostimulants, psychedelics, and entactogens. He is the lead Series Editor for Current Topics in Behavioral Neurosciences, which has completed 43+ volumes. He was involved intensively in the NIMH-funded MATRICS, TURNS, and CNTRICS Programs and has served as a receiving Editor of Neuropsychopharmacology, Neuropharmacology, Psychopharmacology, and Schizophrenia Bulletin, and as Scientific Advisor to European Union’s Innovative Medicine Initiative. He is a Fellow of AAAS, American College of Neuropsychopharmacology (ACNP), and American Psychological Society, Past-President of the International Society for Serotonin Research and the International Behavioral Neuroscience Society, member of Scientific Council of the Brain and Behavior Research Foundation (aka NARSAD), 2011 awardee of Bleuler Prize for Research in the Schizophrenias, and the 2014 Julius Axelrod Mentorship Awardee from ACNP. Dr. Geyer's broad experience as a researcher, grant reviewer, journal editor, and teacher lends invaluable scientific and professional expertise to several organizations, as he provides leadership to develop strong programs in the behavioral psychopharmacology and clinical applications of psychoactive agents.

    Research Interests

    Dr. Geyer’s research has long focused on developing parallel behavioral paradigms in animals and humans for use in psychiatric drug discovery. For example, working with Dr. David Braff, Dr. Geyer published the first study demonstrating that prepulse inhibition (PPI) of startle, a measure of sensorimotor gating, is disrupted in schizophrenic patients in 1978. Since then, research in his laboratory has shown that PPI in animals is disrupted by a number of agents that are psychoactive in humans and in a number of lines of mutant mice. These findings led to the acceptance of PPI as an animal model related to schizophrenia and bipolar mania that reflects aspects of the disease states observed in patients. The CTRIN translational group currently includes five faculty members, Drs. Susan Powell, Victoria Risbrough, Xianjin Zhou, Jared Young, and Adam Halberstadt. In addition, the TRIPEC group includes Drs. William Perry and Arpi Minassian. Our combined laboratories use behavioral, psychophysiological, and cognitive measures combined with psychopharmacological manipulations in rodents and humans to examine the roles of neurotransmitters in behavior, to develop animal models of human drug effects, and to explore information-processing deficits in psychiatric disorders. We use startle measures of habituation, prepulse inhibition, anxiety potentiation, and fear extinction that are deficient in psychiatric disorders and can be mimicked in rodents by pharmacological, developmental, and genetic manipulations. Dr. Geyer has developed a Behavioral Pattern Monitor for use in rats, mice, and humans. These systems provide cross-species translational and multivariate assessments of spatio-temporal patterns of exploratory behavior and are being used in comparisons of schizophrenia and bipolar mania in relationship to corresponding animal models and the effects of psychostimulants in human volunteers. We have explored the effects of classical hallucinogens, dopaminergic psychostimulants, and both direct and indirect serotonin agonists to elucidate their respective mechanisms of action and to reveal the involvement of specific monoamine systems and receptors in behavioral responses to environmental stimuli and in processes such as arousal, habituation, and sensorimotor gating. Animal models of interest in the laboratory include pharmacological manipulations, a variety of developmental perturbations, and genetic models involving strain comparisons, knockouts, and humanized mutant mice, most of which are related to psychotic and/or stress-related disorders. A current focus of the laboratory is the continued development of murine tests of specific cognitive domains relevant to the MATRICS and CNTRICS efforts to treat cognitive deficits in psychiatric disorders

    Collapse Research 
    Collapse Research Activities and Funding
    Early postnatal disruptions to glutamate and GABA systems and their contribution to reward deficits
    NIH/NIMH R01MH108653Jul 15, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Serotonin Club IUPHAR Satellite Meeting
    NIH/NIMH R13MH078663Jul 1, 2006 - Jun 30, 2007
    Role: Principal Investigator
    Stress and CRF System Effects on Information Processing
    NIH/NIMH R01MH074697Jul 1, 2005 - Feb 28, 2015
    Role: Principal Investigator
    Sp4 Pathway in the Modulation of Sensorimotor Gating and Memory
    NIH/NIMH R01MH073991Dec 1, 2004 - Jul 31, 2015
    Role: Principal Investigator
    INHIBITORY DEFICITS IN HUMAN AND ANIMAL MODELS OF BIPOLAR DISORDER
    NIH/NIMH R01MH071916Aug 25, 2004 - Jun 30, 2010
    Role: Principal Investigator
    STARTLE GATING AND LOCOMOTION IN D2-FAMILY KNOCKOUT MICE
    NIH/NIMH R01MH061326Jun 1, 2000 - May 31, 2006
    Role: Principal Investigator
    Monoamine and Hallucinogen Effects on Rodent Behavior
    NIH/NIDA R01DA002925Apr 1, 1996 - Mar 31, 2011
    Role: Principal Investigator
    Developmental Models of Gating Deficits in Schizophrenia
    NIH/NIMH R01MH052885Apr 1, 1995 - Mar 31, 2006
    Role: Principal Investigator
    LIMBIC MONOAMINES, BEHAVIOR, AND PSYCHOPATHOLOGY
    NIH/NIMH K05MH001223Sep 30, 1994 - Dec 31, 1999
    Role: Principal Investigator
    PREPULSE INHIBITION IN RATS REARED IN ISOLATION
    NIH/FIC F06TW001813Aug 4, 1993
    Role: Principal Investigator
    DRUGS OF ABUSE--COMPLEXITY MEASURES CLASSIFY BEHAVIOR
    NIH/NIDA R01DA006325Mar 1, 1990 - Nov 30, 1993
    Role: Principal Investigator
    LIMBIC MONOAMINES, BEHAVIOR, &PSYCHOPATHOLOGY
    NIH/NIMH K02MH000188Sep 1, 1983 - Mar 31, 1989
    Role: Principal Investigator
    HIPPOCAMPAL TRANSMITTER EFFICACY AFTER ANTIDEPRESSANTS
    NIH/NIMH R01MH037954Sep 1, 1983 - Mar 31, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts. Cell Rep. 2020 Jun 02; 31(9):107716. Huckins LM, Chatzinakos C, Breen MS, Hartmann J, Klengel T, da Silva Almeida AC, Dobbyn A, Girdhar K, Hoffman GE, Klengel C, Logue MW, Lori A, Maihofer AX, Morrison FG, Nguyen HT, Park Y, Ruderfer D, Sloofman LG, van Rooij SJH, Baker DG, Chen CY, Cox N, Duncan LE, Geyer MA, Glatt SJ, Im HK, Risbrough VB, Smoller JW, Stein DJ, Yehuda R, Liberzon I, Koenen KC, Jovanovic T, Kellis M, Miller MW, Bacanu SA, Nievergelt CM, Buxbaum JD, Sklar P, Ressler KJ, Stahl EA, Daskalakis NP. PMID: 32492425.
      View in: PubMed   Mentions:    Fields:    
    2. Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter-deficient mice using the 5-choice CPT. Bipolar Disord. 2020 02; 22(1):46-58. Young JW, Geyer MA, Halberstadt AL, van Enkhuizen J, Minassian A, Khan A, Perry W, Eyler LT. PMID: 31025493.
      View in: PubMed   Mentions:    Fields:    
    3. Chronic treatment with a metabotropic mGlu2/3 receptor agonist diminishes behavioral response to a phenethylamine hallucinogen. Psychopharmacology (Berl). 2019 Feb; 236(2):821-830. Halberstadt AL, van der Zee JVF, Chatha M, Geyer MA, Powell SB. PMID: 30448990.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning. Eur Neuropsychopharmacol. 2018 11; 28(11):1217-1231. Milienne-Petiot M, Higa KK, Grim A, Deben D, Groenink L, Twamley EW, Geyer MA, Young JW. PMID: 30213668.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Amphetamine improves mouse and human attention in the 5-choice continuous performance test. Neuropharmacology. 2018 08; 138:87-96. MacQueen DA, Minassian A, Kenton JA, Geyer MA, Perry W, Brigman JL, Young JW. PMID: 29859849.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Overview of the Biography and Legacy of Professor Athina Markou. Biol Psychiatry. 2018 06 01; 83(11):910-912. Geyer MA, Semenova S, Li X, Der-Avakian A, Barnes SA, Grant I. PMID: 29501205.
      View in: PubMed   Mentions:    Fields:    
    7. Effective Use of Animal Models for Therapeutic Development in Psychiatric and Substance Use Disorders. Biol Psychiatry. 2018 06 01; 83(11):915-923. Phillips AG, Geyer MA, Robbins TW. PMID: 29478700.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Individual variation in working memory is associated with fear extinction performance. Behav Res Ther. 2018 03; 102:52-59. Stout DM, Acheson DT, Moore TM, Gur RC, Baker DG, Geyer MA, Risbrough VB. PMID: 29331727.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Effect of Hallucinogens on Unconditioned Behavior. Curr Top Behav Neurosci. 2018; 36:159-199. Halberstadt AL, Geyer MA. PMID: 28224459.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    10. Dopamine transporter knockdown mice in the behavioral pattern monitor: A robust, reproducible model for mania-relevant behaviors. Pharmacol Biochem Behav. 2019 03; 178:42-50. Kwiatkowski MA, Hellemann G, Sugar CA, Cope ZA, Minassian A, Perry W, Geyer MA, Young JW. PMID: 29289701.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    11. The COMT Val158Met Polymorphism and Exploratory Behavior in Bipolar Mania. Mol Neuropsychiatry. 2018 Feb; 3(3):151-156. Minassian A, Young JW, Geyer MA, Kelsoe JR, Perry W. PMID: 29594134.
      View in: PubMed   Mentions:
    12. Amphetamine Modestly Improves Conners' Continuous Performance Test Performance in Healthy Adults. J Int Neuropsychol Soc. 2018 03; 24(3):283-293. MacQueen DA, Minassian A, Henry BL, Geyer MA, Young JW, Perry W. PMID: 29032769.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma. Depress Anxiety. 2018 01; 35(1):32-42. Deslauriers J, Acheson DT, Maihofer AX, Nievergelt CM, Baker DG, Geyer MA, Risbrough VB. PMID: 28833952.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 08 02; 8:16140. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. PMID: 28767105.
      View in: PubMed   Mentions: 1     Fields:    
    15. Modafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species. Neuropharmacology. 2017 Oct; 125:254-262. Cope ZA, Minassian A, Kreitner D, MacQueen DA, Milienne-Petiot M, Geyer MA, Perry W, Young JW. PMID: 28774856.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 06 14; 8:15805. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. PMID: 28613276.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms. Depress Anxiety. 2017 08; 34(8):723-733. Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB. PMID: 28489272.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Brexpiprazole reduces hyperactivity, impulsivity, and risk-preference behavior in mice with dopamine transporter knockdown-a model of mania. Psychopharmacology (Berl). 2017 Mar; 234(6):1017-1028. Milienne-Petiot M, Geyer MA, Arnt J, Young JW. PMID: 28160035.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice. Behav Brain Res. 2017 04 14; 323:117-123. Deslauriers J, van Wijngaarde M, Geyer MA, Powell S, Risbrough VB. PMID: 28159589.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Striatal dopamine D1 receptor suppression impairs reward-associative learning. Behav Brain Res. 2017 04 14; 323:100-110. Higa KK, Young JW, Ji B, Nichols DE, Geyer MA, Zhou X. PMID: 28143767.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    21. Athina Markou. Neuropsychopharmacology. 2016 Dec; 41(13):3121-3122. Geyer MA. PMID: 27818512.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females. Neuropsychopharmacology. 2016 12; 41(13):2963-2964. Ahmari SE, Risbrough VB, Geyer MA, Simpson HB. PMID: 27818517.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania. Neuropharmacology. 2017 02; 113(Pt A):260-270. Milienne-Petiot M, Kesby JP, Graves M, van Enkhuizen J, Semenova S, Minassian A, Markou A, Geyer MA, Young JW. PMID: 27732870.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    24. Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next. J Psychopharmacol. 2016 11; 30(11):1072-1081. Swerdlow NR, Braff DL, Geyer MA. PMID: 27539931.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    25. Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges. Psychopharmacology (Berl). 2016 Oct; 233(19-20):3513-25. Cope ZA, Halberstadt AL, van Enkhuizen J, Flynn AD, Breier M, Swerdlow NR, Geyer MA, Young JW. PMID: 27534540.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    26. Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets. Nat Rev Drug Discov. 2016 Jul; 15(7):516. Bespalov A, Steckler T, Altevogt B, Koustova E, Skolnick P, Deaver D, Millan MJ, Bastlund JF, Doller D, Witkin J, Moser P, O'Donnell P, Ebert U, Geyer MA, Prinssen E, Ballard T, Macleod M. PMID: 27312728.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    27. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. 2016 08; 107:364-375. Halberstadt AL, Sindhunata IS, Scheffers K, Flynn AD, Sharp RF, Geyer MA, Young JW. PMID: 27020041.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    28. PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER. Depress Anxiety. 2016 Mar; 33(3):238-46. Steinman SA, Ahmari SE, Choo T, Kimeldorf MB, Feit R, Loh S, Risbrough V, Geyer MA, Steinglass JE, Wall M, Schneier FR, Fyer AJ, Simpson HB. PMID: 26878422.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES. Depress Anxiety. 2016 Mar; 33(3):192-202. Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB. PMID: 26878585.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Wet or dry: translatable "water mazes" for mice and humans. J Clin Invest. 2016 Feb; 126(2):477-9. Higa KK, Young JW, Geyer MA. PMID: 26784538.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    31. Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines. J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9. Yurgil KA, Clifford RE, Risbrough VB, Geyer MA, Huang M, Barkauskas DA, Vasterling JJ, Baker DG. PMID: 25699623.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Locomotor Profiling from Rodents to the Clinic and Back Again. Curr Top Behav Neurosci. 2016; 28:287-303. Young JW, Minassian A, Geyer MA. PMID: 27418071.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    33. Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood. Neuropsychopharmacology. 2016 May; 41(6):1681-90. Toth M, Flandreau EI, Deslauriers J, Geyer MA, Mansuy IM, Merlo Pich E, Risbrough VB. PMID: 26538448.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    34. Lysergic Acid Diethylamide and Psilocybin Revisited. Biol Psychiatry. 2015 Oct 15; 78(8):516-8. Geyer MA. PMID: 26386624.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    35. Amphetamine increases activity but not exploration in humans and mice. Psychopharmacology (Berl). 2016 Jan; 233(2):225-33. Minassian A, Young JW, Cope ZA, Henry BL, Geyer MA, Perry W. PMID: 26449721.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    36. Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 2015 Oct; 72(10):979-86. Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB. PMID: 26353072.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    37. Investigating the underlying mechanisms of aberrant behaviors in bipolar disorder from patients to models: Rodent and human studies. Neurosci Biobehav Rev. 2015 Nov; 58:4-18. van Enkhuizen J, Geyer MA, Minassian A, Perry W, Henry BL, Young JW. PMID: 26297513.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    38. Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features. Psychopharmacology (Berl). 2015 Sep; 232(18):3455-67. van Enkhuizen J, Milienne-Petiot M, Geyer MA, Young JW. PMID: 26141192.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    39. Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063. Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. PMID: 26037489.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    40. Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. Dev Neurosci. 2015; 37(3):253-62. Powell SB, Khan A, Young JW, Scott CN, Buell MR, Caldwell S, Tsan E, de Jong LA, Acheson DT, Lucero J, Geyer MA, Behrens MM. PMID: 26022788.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    41. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology. 2015 Nov; 40(12):2715-26. Young JW, Kamenski ME, Higa KK, Light GA, Geyer MA, Zhou X. PMID: 25907107.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    42. Cell type-specific modifications of corticotropin-releasing factor (CRF) and its type 1 receptor (CRF1) on startle behavior and sensorimotor gating. Psychoneuroendocrinology. 2015 Mar; 53:16-28. Flandreau E, Risbrough V, Lu A, Ableitner M, Geyer MA, Holsboer F, Deussing JM. PMID: 25575243.
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    126. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Hum Mol Genet. 2009 Oct 15; 18(20):3914-25. Suzuki G, Harper KM, Hiramoto T, Funke B, Lee M, Kang G, Buell M, Geyer MA, Kucherlapati R, Morrow B, Männistö PT, Agatsuma S, Hiroi N. PMID: 19617637.
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    134. Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. Hum Mol Genet. 2009 May 01; 18(9):1652-60. Suzuki G, Harper KM, Hiramoto T, Sawamura T, Lee M, Kang G, Tanigaki K, Buell M, Geyer MA, Trimble WS, Agatsuma S, Hiroi N. PMID: 19240081.
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    135. The 5-choice continuous performance test: evidence for a translational test of vigilance for mice. PLoS One. 2009; 4(1):e4227. Young JW, Light GA, Marston HM, Sharp R, Geyer MA. PMID: 19156216.
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    136. Selecting paradigms from cognitive neuroscience for translation into use in clinical trials: proceedings of the third CNTRICS meeting. Schizophr Bull. 2009 Jan; 35(1):109-14. Barch DM, Carter CS, Arnsten A, Buchanan RW, Cohen JD, Geyer M, Green MF, Krystal JH, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. PMID: 19023126.
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    137. Perception measurement in clinical trials of schizophrenia: promising paradigms from CNTRICS. Schizophr Bull. 2009 Jan; 35(1):163-81. Green MF, Butler PD, Chen Y, Geyer MA, Silverstein S, Wynn JK, Yoon JH, Zemon V. PMID: 19023123.
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    138. CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues. Neuropsychopharmacology. 2009 May; 34(6):1494-503. Risbrough VB, Geyer MA, Hauger RL, Coste S, Stenzel-Poore M, Wurst W, Holsboer F. PMID: 19020499.
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    139. Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry. 2009 Mar 01; 65(5):401-8. Shanahan NA, Holick Pierz KA, Masten VL, Waeber C, Ansorge M, Gingrich JA, Geyer MA, Hen R, Dulawa SC. PMID: 19013555.
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    140. Habituation revisited: an updated and revised description of the behavioral characteristics of habituation. Neurobiol Learn Mem. 2009 Sep; 92(2):135-8. Rankin CH, Abrams T, Barry RJ, Bhatnagar S, Clayton DF, Colombo J, Coppola G, Geyer MA, Glanzman DL, Marsland S, McSweeney FK, Wilson DA, Wu CF, Thompson RF. PMID: 18854219.
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    141. Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology. 2009 Jan; 34(1):74-89. Markou A, Chiamulera C, Geyer MA, Tricklebank M, Steckler T. PMID: 18830240.
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    142. Serotonin research: contributions to understanding psychoses. Trends Pharmacol Sci. 2008 Sep; 29(9):445-53. Geyer MA, Vollenweider FX. PMID: 19086254.
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    143. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol. 2008 Sep; 19(5-6):562-5. Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. PMID: 18690110.
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    144. Developing translational animal models for symptoms of schizophrenia or bipolar mania. Neurotox Res. 2008 Aug; 14(1):71-8. Geyer MA. PMID: 18790726.
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    145. Habituation and sensitization of acoustic startle: opposite influences of dopamine D1 and D2-family receptors. Neurobiol Learn Mem. 2009 Sep; 92(2):243-8. Halberstadt AL, Geyer MA. PMID: 18644244.
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    146. Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. Psychopharmacology (Berl). 2008 Nov; 201(1):55-66. Halberstadt AL, Buell MR, Masten VL, Risbrough VB, Geyer MA. PMID: 18604652.
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    147. Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative. Biol Psychiatry. 2008 Jul 01; 64(1):4-10. Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. PMID: 18466880.
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    148. Prepulse inhibition and "psychosis-proneness" in healthy individuals: an fMRI study. Eur Psychiatry. 2008 Jun; 23(4):274-80. Kumari V, Antonova E, Geyer MA. PMID: 18222069.
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    149. Cortical grey matter volume and sensorimotor gating in schizophrenia. Cortex. 2008 Oct; 44(9):1206-14. Kumari V, Fannon D, Geyer MA, Premkumar P, Antonova E, Simmons A, Kuipers E. PMID: 18761134.
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    150. Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology. 2008 Oct; 33(11):2648-56. Doherty JM, Masten VL, Powell SB, Ralph RJ, Klamer D, Low MJ, Geyer MA. PMID: 18075489.
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    151. Spontaneous nicotine withdrawal potentiates the effects of stress in rats. Neuropsychopharmacology. 2008 Aug; 33(9):2131-8. Jonkman S, Risbrough VB, Geyer MA, Markou A. PMID: 18033237.
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    152. Patients with premenstrual dysphoric disorder have increased startle response across both cycle phases and lower levels of prepulse inhibition during the late luteal phase of the menstrual cycle. Neuropsychopharmacology. 2008 Aug; 33(9):2283-90. Kask K, Gulinello M, Bäckström T, Geyer MA, Sundström-Poromaa I. PMID: 17940552.
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    153. Wayne Fenton's impact on academic neuroscience. Schizophr Bull. 2007 Sep; 33(5):1156-9. Geyer MA, Tamminga CA. PMID: 17617663.
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    154. A reverse-translational approach to bipolar disorder: rodent and human studies in the Behavioral Pattern Monitor. Neurosci Biobehav Rev. 2007; 31(6):882-96. Young JW, Minassian A, Paulus MP, Geyer MA, Perry W. PMID: 17706782.
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    155. Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition. Biol Psychiatry. 2008 Jan 01; 63(1):98-105. Semenova S, Geyer MA, Sutcliffe JG, Markou A, Hedlund PB. PMID: 17531208.
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    156. Haloperidol differentially modulates prepulse inhibition and p50 suppression in healthy humans stratified for low and high gating levels. Neuropsychopharmacology. 2008 Feb; 33(3):497-512. Csomor PA, Stadler RR, Feldon J, Yee BK, Geyer MA, Vollenweider FX. PMID: 17460616.
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    157. Overview of animal models of schizophrenia. Curr Protoc Neurosci. 2007 Apr; Chapter 9:Unit 9.24. Powell SB, Geyer MA. PMID: 18428667.
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    158. The indirect serotonergic agonist d-fenfluramine and prepulse inhibition in healthy men. Neuropharmacology. 2007 Mar; 52(4):1088-94. Abel KM, Allin M, van Amelsvoort T, Hemsley D, Geyer MA. PMID: 17306313.
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    159. The effects of the preferential 5-HT2A agonist psilocybin on prepulse inhibition of startle in healthy human volunteers depend on interstimulus interval. Neuropsychopharmacology. 2007 Sep; 32(9):1876-87. Vollenweider FX, Csomor PA, Knappe B, Geyer MA, Quednow BB. PMID: 17299516.
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    160. Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating. Pharmacol Biochem Behav. 2007 Mar; 86(3):550-8. Vinkers CH, Risbrough VB, Geyer MA, Caldwell S, Low MJ, Hauger RL. PMID: 17324452.
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    161. The family of sensorimotor gating disorders: comorbidities or diagnostic overlaps? Neurotox Res. 2006 Dec; 10(3-4):211-20. Geyer MA. PMID: 17197371.
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    162. The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl). 2006 Dec; 189(3):319-29. Krebs-Thomson K, Ruiz EM, Masten V, Buell M, Geyer MA. PMID: 17013638.
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    163. The neural correlates of habituation of response to startling tactile stimuli presented in a functional magnetic resonance imaging environment. Psychiatry Res. 2006 Nov 22; 148(1):1-10. McDowell JE, Brown GG, Lazar N, Camchong J, Sharp R, Krebs-Thomson K, Eyler LT, Braff DL, Geyer MA. PMID: 17000088.
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    164. A fMRI investigation of startle gating deficits in schizophrenia patients treated with typical or atypical antipsychotics. Int J Neuropsychopharmacol. 2007 Aug; 10(4):463-77. Kumari V, Antonova E, Geyer MA, Ffytche D, Williams SC, Sharma T. PMID: 16923324.
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    165. Prepulse inhibition and P50 suppression: commonalities and dissociations. Psychiatry Res. 2006 Aug 30; 143(2-3):147-58. Oranje B, Geyer MA, Bocker KB, Leon Kenemans J, Verbaten MN. PMID: 16879870.
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    166. Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology. 2006 Nov; 31(11):2349-58. Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer MA. PMID: 16855533.
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    167. Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology. 2006 Sep; 51(3):457-65. Barr AM, Powell SB, Markou A, Geyer MA. PMID: 16762376.
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    168. A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biol Psychiatry. 2006 Aug 01; 60(3):253-64. Moore H, Jentsch JD, Ghajarnia M, Geyer MA, Grace AA. PMID: 16581031.
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    169. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology. 2006 Mar; 31(3):506-15. Swerdlow NR, Geyer MA, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP. PMID: 16123772.
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    170. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist. J Pharmacol Exp Ther. 2006 May; 317(2):910-8. Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE. PMID: 16469866.
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    171. A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia. Psychopharmacology (Berl). 2006 Mar; 184(3-4):589-99. Postma P, Gray JA, Sharma T, Geyer M, Mehrotra R, Das M, Zachariah E, Hines M, Williams SC, Kumari V. PMID: 16456657.
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    172. Isolation rearing of mice induces deficits in prepulse inhibition of the startle response. Behav Brain Res. 2006 Apr 25; 169(1):162-7. Varty GB, Powell SB, Lehmann-Masten V, Buell MR, Geyer MA. PMID: 16406103.
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    173. Are cross-species measures of sensorimotor gating useful for the discovery of procognitive cotreatments for schizophrenia? Dialogues Clin Neurosci. 2006; 8(1):9-16. Geyer MA. PMID: 16640109.
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    174. New approaches to measurement and treatment research to improve cognition in schizophrenia. Schizophr Bull. 2005 Oct; 31(4):806-9. Geyer MA, Heinssen R. PMID: 16166608.
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    175. An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition. J Pharmacol Exp Ther. 2005 Dec; 315(3):1163-71. Ong JC, Brody SA, Large CH, Geyer MA. PMID: 16123308.
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    176. Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia. Schizophr Bull. 2005 Oct; 31(4):888-94. Floresco SB, Geyer MA, Gold LH, Grace AA. PMID: 16079387.
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    177. The effects of sex and neonatal maternal separation on fear-potentiated and light-enhanced startle. Behav Brain Res. 2005 Jun 20; 161(2):190-6. de Jongh R, Geyer MA, Olivier B, Groenink L. PMID: 15878207.
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    178. On the waveform of the acoustic startle blink in the paradigm of prepulse inhibition - methodological and physiological aspects. Neuropsychobiology. 2005; 52(1):24-7. Meincke U, Light GA, Geyer MA, Braff DL. PMID: 15942260.
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    180. Yohimbine disrupts prepulse inhibition in rats via action at 5-HT1A receptors, not alpha2-adrenoceptors. Psychopharmacology (Berl). 2005 Jul; 180(3):491-500. Powell SB, Palomo J, Carasso BS, Bakshi VP, Geyer MA. PMID: 15719216.
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    181. Anxiogenic treatments do not increase fear-potentiated startle in mice. Biol Psychiatry. 2005 Jan 01; 57(1):33-43. Risbrough VB, Geyer MA. PMID: 15607298.
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    182. Information-processing deficits and cognitive dysfunction in panic disorder. J Psychiatry Neurosci. 2005 Jan; 30(1):37-43. Ludewig S, Geyer MA, Ramseier M, Vollenweider FX, Rechsteiner E, Cattapan-Ludewig K. PMID: 15644996.
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    183. Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis--a longitudinal study. Eur Arch Psychiatry Clin Neurosci. 2004 Dec; 254(6):415-21. Meincke U, Mörth D, Voss T, Thelen B, Geyer MA, Gouzoulis-Mayfrank E. PMID: 15538598.
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    184. Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation. Biol Psychiatry. 2004 Aug 15; 56(4):296-9. Harte MK, Powell SB, Reynolds LM, Swerdlow NR, Geyer MA, Reynolds GP. PMID: 15312819.
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    185. Endogenous kynurenic acid disrupts prepulse inhibition. Biol Psychiatry. 2004 Aug 15; 56(4):255-60. Erhardt S, Schwieler L, Emanuelsson C, Geyer M. PMID: 15312813.
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    187. The balance between approach and avoidance behaviors in a novel object exploration paradigm in mice. Behav Brain Res. 2004 Jul 09; 152(2):341-9. Powell SB, Geyer MA, Gallagher D, Paulus MP. PMID: 15196802.
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    188. Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia. Psychiatry Res. 2004 Apr 15; 126(1):51-61. Meincke U, Light GA, Geyer MA, Braff DL, Gouzoulis-Mayfrank E. PMID: 15081627.
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    189. The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology. 2004 Feb; 29(2):221-8. Barr AM, Lehmann-Masten V, Paulus M, Gainetdinov RR, Caron MG, Geyer MA. PMID: 14603268.
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    194. Assessment of murine startle reactivity, prepulse inhibition, and habituation. Curr Protoc Neurosci. 2003 Nov; Chapter 8:Unit 8.17. Geyer MA, Dulawa SC. PMID: 18428584.
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    197. Cognition in schizophrenia: from basic science to clinical treatment. Psychopharmacology (Berl). 2003 Sep; 169(3-4):213-4. Harvey PD, Geyer MA, Robbins TW, Krystal JH. PMID: 12955286.
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    199. Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice. Psychopharmacology (Berl). 2003 Nov; 170(2):178-87. Risbrough VB, Hauger RL, Pelleymounter MA, Geyer MA. PMID: 12845406.
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    200. The acoustic startle reflex and its modulation: effects of age and gender in humans. Biol Psychol. 2003 Jul; 63(3):311-23. Ludewig K, Ludewig S, Seitz A, Obrist M, Geyer MA, Vollenweider FX. PMID: 12853174.
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    201. Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology. 2003 May; 44(6):729-37. Abel KM, Allin MP, Hemsley DR, Geyer MA. PMID: 12681371.
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    202. Lamotrigine prevents ketamine but not amphetamine-induced deficits in prepulse inhibition in mice. Psychopharmacology (Berl). 2003 Sep; 169(3-4):240-6. Brody SA, Geyer MA, Large CH. PMID: 12698229.
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    203. The relationship of age to prepulse inhibition and habituation of the acoustic startle response. Biol Psychol. 2003 Mar; 62(3):175-95. Ellwanger J, Geyer MA, Braff DL. PMID: 12633977.
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    204. RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology. 2003 Mar; 44(4):473-81. Powell SB, Paulus MP, Hartman DS, Godel T, Geyer MA. PMID: 12646284.
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    205. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biol Psychiatry. 2003 Feb 15; 53(4):352-9. Ralph-Williams RJ, Paulus MP, Zhuang X, Hen R, Geyer MA. PMID: 12586455.
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    206. Neural correlates of tactile prepulse inhibition: a functional MRI study in normal and schizophrenic subjects. Psychiatry Res. 2003 Feb 15; 122(2):99-113. Kumari V, Gray JA, Geyer MA, ffytche D, Soni W, Mitterschiffthaler MT, Vythelingum GN, Simmons A, Williams SC, Sharma T. PMID: 12714174.
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    207. Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice. Neuropsychopharmacology. 2003 Jan; 28(1):108-18. Ralph-Williams RJ, Lehmann-Masten V, Geyer MA. PMID: 12496946.
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    208. Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice. J Neurosci. 2002 Nov 01; 22(21):9604-11. Ralph-Williams RJ, Lehmann-Masten V, Otero-Corchon V, Low MJ, Geyer MA. PMID: 12417685.
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    209. GABA-A and 5-HT1A receptor agonists block expression of fear-potentiated startle in mice. Neuropsychopharmacology. 2003 Apr; 28(4):654-63. Risbrough VB, Brodkin JD, Geyer MA. PMID: 12655310.
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    210. Isolation rearing-induced deficits in prepulse inhibition and locomotor habituation are not potentiated by water deprivation. Physiol Behav. 2002 Sep; 77(1):55-64. Powell SB, Swerdlow NR, Pitcher LK, Geyer MA. PMID: 12213502.
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    211. Prestimulus effects on startle magnitude: sensory or motor? Behav Neurosci. 2002 Aug; 116(4):672-81. Swerdlow NR, Shoemaker JM, Stephany N, Wasserman L, Ro HJ, Geyer MA. PMID: 12148934.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    212. Developmental markers of psychiatric disorders as identified by sensorimotor gating. Neurotox Res. 2002 Aug-Sep; 4(5-6):489-502. Powell SB, Geyer MA. PMID: 12754162.
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    213. Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype? Am J Psychiatry. 2002 May; 159(5):869-71. Cadenhead KS, Light GA, Geyer MA, McDowell JE, Braff DL. PMID: 11986147.
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    214. Stability of the acoustic startle reflex, prepulse inhibition, and habituation in schizophrenia. Schizophr Res. 2002 May 01; 55(1-2):129-37. Ludewig K, Geyer MA, Etzensberger M, Vollenweider FX. PMID: 11955972.
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    215. Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats. Pharmacol Biochem Behav. 2002 Apr; 71(4):569-80. Martinez-Price DL, Geyer MA. PMID: 11888548.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    216. Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone. Biol Psychiatry. 2002 Apr 01; 51(7):583-90. Dirks A, Groenink L, Schipholt MI, van der Gugten J, Hijzen TH, Geyer MA, Olivier B. PMID: 11950460.
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    217. Acute psychological and neurophysiological effects of MDMA in humans. J Psychoactive Drugs. 2002 Apr-Jun; 34(2):171-84. Vollenweider FX, Liechti ME, Gamma A, Greer G, Geyer M. PMID: 12691207.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    218. Dopamine agonist effects on startle and sensorimotor gating in normal male subjects: time course studies. Psychopharmacology (Berl). 2002 May; 161(2):189-201. Swerdlow NR, Eastvold A, Karban B, Ploum Y, Stephany N, Geyer MA, Cadenhead K, Auerbach PP. PMID: 11981599.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    219. "Typical" but not "atypical" antipsychotic effects on startle gating deficits in prepubertal rats. Psychopharmacology (Berl). 2002 Apr; 161(1):38-46. Martinez ZA, Platten A, Pollack E, Shoemaker J, Ro H, Pitcher L, Geyer MA, Swerdlow NR. PMID: 11967629.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    220. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl). 2001 Jul; 156(2-3):117-54. Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR. PMID: 11549216.
      View in: PubMed   Mentions: 428     Fields:    Translation:HumansAnimals
    221. Effects of LU-111995 in three models of disrupted prepulse inhibition in rats. J Pharmacol Exp Ther. 1999 Aug; 290(2):716-24. Geyer MA, Swerdlow NR, Lehmann-Masten V, Teschendorf HJ, Traut M, Gross G. PMID: 10411583.
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