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Organic anion transporters in remote sensing and organ crosstalk. Pharmacol Ther. 2024 Nov; 263:108723.
Granados JC, Nigam SK. PMID: 39284369.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3. Nutrients. 2024 Jul 12; 16(14).
Falah K, Zhang P, Nigam AK, Maity K, Chang G, Granados JC, Momper JD, Nigam SK. PMID: 39064685; PMCID: PMC11280313.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning. Pharmaceutics. 2024 Apr 26; 16(5).
Nigam AK, Momper JD, Ojha AA, Nigam SK. PMID: 38794254; PMCID: PMC11125978.
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PubMed Mentions:
-
Remote effects of kidney drug transporter OAT1 on gut microbiome composition and urate homeostasis. JCI Insight. 2023 Nov 08; 8(21).
Ermakov VS, Granados JC, Nigam SK. PMID: 37937647; PMCID: PMC10721261.
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PubMed Mentions:
4 Fields:
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Role of the Microbiome in Gut-Heart-Kidney Cross Talk. Circ Res. 2023 04 14; 132(8):1064-1083.
Glorieux G, Nigam SK, Vanholder R, Verbeke F. PMID: 37053274.
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PubMed Mentions:
18 Fields:
Translation:
Humans
-
Loss of the Kidney Urate Transporter, Urat1, Leads to Disrupted Redox Homeostasis in Mice. Antioxidants (Basel). 2023 Mar 22; 12(3).
Jamshidi N, Nigam KB, Nigam SK. PMID: 36979028; PMCID: PMC10045411.
View in:
PubMed Mentions:
1
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Regulation of Human Endogenous Metabolites by Drug Transporters and Drug Metabolizing Enzymes: An Analysis of Targeted SNP-Metabolite Associations. Metabolites. 2023 Jan 24; 13(2).
Granados JC, Watrous JD, Long T, Rosenthal SB, Cheng S, Jain M, Nigam SK. PMID: 36837791; PMCID: PMC9958903.
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PubMed Mentions:
3
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The kidney drug transporter OAT1 regulates gut microbiome-dependent host metabolism. JCI Insight. 2023 01 24; 8(2).
Granados JC, Ermakov V, Maity K, Vera DR, Chang G, Nigam SK. PMID: 36692015; PMCID: PMC9977316.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Drug transporters OAT1 and OAT3 have specific effects on multiple organs and gut microbiome as revealed by contextualized metabolic network reconstructions. Sci Rep. 2022 10 31; 12(1):18308.
Jamshidi N, Nigam SK. PMID: 36316339; PMCID: PMC9622871.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
OAT, OATP, and MRP Drug Transporters and the Remote Sensing and Signaling Theory. Annu Rev Pharmacol Toxicol. 2023 Jan 20; 63:637-660.
Nigam SK, Granados JC. PMID: 36206988.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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AHR is a master regulator of diverse pathways in endogenous metabolism. Sci Rep. 2022 10 05; 12(1):16625.
Granados JC, Falah K, Koo I, Morgan EW, Perdew GH, Patterson AD, Jamshidi N, Nigam SK. PMID: 36198709; PMCID: PMC9534852.
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PubMed Mentions:
15 Fields:
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Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma. Cancers (Basel). 2022 Sep 29; 14(19).
Whisenant TC, Nigam SK. PMID: 36230695; PMCID: PMC9563088.
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PubMed Mentions:
7
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Blockade of Organic Anion Transport in Humans After Treatment With the Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine. Clin Pharmacol Ther. 2022 09; 112(3):653-664.
Granados JC, Bhatnagar V, Nigam SK. PMID: 35490380; PMCID: PMC9398954.
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PubMed Mentions:
12 Fields:
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A Biological Basis for Pharmacokinetics: The Remote Sensing and Signaling Theory. Clin Pharmacol Ther. 2022 09; 112(3):456-460.
Nigam SK, Granados JC. PMID: 35598078; PMCID: PMC9398931.
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PubMed Mentions:
4 Fields:
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What If Not All Metabolites from the Uremic Toxin Generating Pathways Are Toxic? A Hypothesis. Toxins (Basel). 2022 03 17; 14(3).
Vanholder R, Nigam SK, Burtey S, Glorieux G. PMID: 35324718; PMCID: PMC8953523.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo. Int J Mol Sci. 2021 Dec 14; 22(24).
Zhang P, Azad P, Engelhart DC, Haddad GG, Nigam SK. PMID: 34948211; PMCID: PMC8706193.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Altered pro-inflammatory and anti-inflammatory plasma cytokines levels in children with Down's syndrome: A meta-analysis. J Family Med Prim Care. 2021 Oct; 10(10):3568-3574.
Nigam N, Singh PK, Raizada N, Singh BP, Tripathi S, Agrawal M, Gupta H, Singh S, Fatima G, Nigam SK, Saxena SK. PMID: 34934648; PMCID: PMC8653489.
View in:
PubMed Mentions:
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Molecular Properties of Drugs Handled by Kidney OATs and Liver OATPs Revealed by Chemoinformatics and Machine Learning: Implications for Kidney and Liver Disease. Pharmaceutics. 2021 Oct 18; 13(10).
Nigam AK, Ojha AA, Li JG, Shi D, Bhatnagar V, Nigam KB, Abagyan R, Nigam SK. PMID: 34684013; PMCID: PMC8538396.
View in:
PubMed Mentions:
9
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Renal and non-renal response of ABC and SLC transporters in chronic kidney disease. Expert Opin Drug Metab Toxicol. 2021 May; 17(5):515-542.
Torres AM, Dnyanmote AV, Granados JC, Nigam SK. PMID: 33749483.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Uremic Toxins in Organ Crosstalk. Front Med (Lausanne). 2021; 8:592602.
Lowenstein J, Nigam SK. PMID: 33937275; PMCID: PMC8085272.
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PubMed Mentions:
20
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A key role for the transporter OAT1 in systemic lipid metabolism. J Biol Chem. 2021 Jan-Jun; 296:100603.
Granados JC, Nigam AK, Bush KT, Jamshidi N, Nigam SK. PMID: 33785360; PMCID: PMC8102404.
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PubMed Mentions:
12 Fields:
Translation:
Animals
-
Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3. J Biol Chem. 2021 Jan-Jun; 296:100575.
Granados JC, Richelle A, Gutierrez JM, Zhang P, Zhang X, Bhatnagar V, Lewis NE, Nigam SK. PMID: 33757768; PMCID: PMC8102410.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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MTHFR C677T, Prothrombin G20210A, and Factor V Leiden (G1691A) Polymorphism and Beta-Thalassemia Risk: A Meta-Analysis. Cureus. 2020 Sep 30; 12(9):e10743.
Nigam N, Singh PK, Agrawal M, Nigam S, Gupta H, Saxena S. PMID: 33150118; PMCID: PMC7603879.
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PubMed Mentions:
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The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology. Clin Pharmacol Ther. 2020 07; 108(1):40-53.
Nigam SK, Bush KT, Bhatnagar V, Poloyac SM, Momper JD. PMID: 32119114; PMCID: PMC7292762.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease. JCI Insight. 2020 04 09; 5(7).
Bush KT, Singh P, Nigam SK. PMID: 32271169; PMCID: PMC7205256.
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PubMed Mentions:
31 Fields:
Translation:
Animals
-
Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Int J Mol Sci. 2020 Mar 15; 21(6).
Engelhart DC, Azad P, Ali S, Granados JC, Haddad GG, Nigam SK. PMID: 32183456; PMCID: PMC7139749.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs. Int J Mol Sci. 2020 Mar 05; 21(5).
Engelhart DC, Granados JC, Shi D, Saier Jr MH, Baker ME, Abagyan R, Nigam SK. PMID: 32150922; PMCID: PMC7084758.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning. J Biol Chem. 2020 02 14; 295(7):1829-1842.
Nigam AK, Li JG, Lall K, Shi D, Bush KT, Bhatnagar V, Abagyan R, Nigam SK. PMID: 31896576; PMCID: PMC7029110.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis. Sci Rep. 2019 08 15; 9(1):11879.
Rosenthal SB, Bush KT, Nigam SK. PMID: 31417100; PMCID: PMC6695406.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling. Nat Rev Nephrol. 2019 05; 15(5):301-316.
Nigam SK, Bush KT. PMID: 30728454; PMCID: PMC6619437.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation. Clin J Am Soc Nephrol. 2019 04 05; 14(4):540-548.
Momper JD, Yang J, Gockenbach M, Vaida F, Nigam SK. PMID: 30885911; PMCID: PMC6450358.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Temporal transcriptomic analysis of metabolic genes in maternal organs and placenta during murine pregnancy. Biol Reprod. 2018 12 01; 99(6):1255-1265.
Paquette A, Baloni P, Holloman AB, Nigam S, Bammler T, Mao Q, Price ND. PMID: 29939228; PMCID: PMC6692859.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development. Am J Med Genet A. 2019 01; 179(1):71-77.
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P. PMID: 30422383.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The systems biology of uric acid transporters: the role of remote sensing and signaling. Curr Opin Nephrol Hypertens. 2018 07; 27(4):305-313.
Nigam SK, Bhatnagar V. PMID: 29847376; PMCID: PMC6275126.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication. Expert Opin Drug Metab Toxicol. 2018 Jun; 14(6):561-570.
Momper JD, Nigam SK. PMID: 29746174; PMCID: PMC6277044.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin. Am J Physiol Renal Physiol. 2018 08 01; 315(2):F386-F394.
Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolic I, Vallon V. PMID: 29412698; PMCID: PMC6139528.
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PubMed Mentions:
20 Fields:
Translation:
Animals
-
The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease. Annu Rev Pharmacol Toxicol. 2018 01 06; 58:663-687.
Nigam SK. PMID: 29309257; PMCID: PMC6225997.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut-liver-kidney axis. J Biol Chem. 2017 09 22; 292(38):15789-15803.
Bush KT, Wu W, Lun C, Nigam SK. PMID: 28765282; PMCID: PMC5612110.
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PubMed Mentions:
47 Fields:
Translation:
Animals
-
Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes. Sci Rep. 2017 07 10; 7(1):4939.
Wu W, Bush KT, Nigam SK. PMID: 28694431; PMCID: PMC5504054.
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PubMed Mentions:
94 Fields:
Translation:
Animals
-
Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach. J Pharmacol Exp Ther. 2016 10; 359(1):215-29.
Liu HC, Goldenberg A, Chen Y, Lun C, Wu W, Bush KT, Balac N, Rodriguez P, Abagyan R, Nigam SK. PMID: 27488918; PMCID: PMC5034704.
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PubMed Mentions:
33 Fields:
Translation:
Cells
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An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network. J Biol Chem. 2016 09 09; 291(37):19474-86.
Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK. PMID: 27440044; PMCID: PMC5016685.
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PubMed Mentions:
23 Fields:
Translation:
Animals
-
Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2. PLoS One. 2016; 11(4):e0152969.
He X, Garza D, Nigam SK, Chang G. PMID: 27046168; PMCID: PMC4821612.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling. Clin Kidney J. 2016 Jun; 9(3):444-53.
Bhatnagar V, Richard EL, Wu W, Nievergelt CM, Lipkowitz MS, Jeff J, Maihofer AX, Nigam SK. PMID: 27274832; PMCID: PMC4886906.
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PubMed Mentions:
59
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Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers. Drug Metab Dispos. 2016 07; 44(7):1050-60.
Martovetsky G, Bush KT, Nigam SK. PMID: 27044799; PMCID: PMC4931883.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 2015 Nov 10; 4.
Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. PMID: 26554899; PMCID: PMC4631902.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. PLoS One. 2015; 10(11):e0140569.
Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Wu W, Nigam SK. PMID: 26536134; PMCID: PMC4633038.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters. Clin J Am Soc Nephrol. 2015 Nov 06; 10(11):2039-49.
Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. PMID: 26490509; PMCID: PMC4633783.
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PubMed Mentions:
100 Fields:
Translation:
HumansCells
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Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors. Drug Metab Dispos. 2015 Dec; 43(12):1855-63.
Wu W, Bush KT, Liu HC, Zhu C, Abagyan R, Nigam SK. PMID: 26358290; PMCID: PMC4658493.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clin Pharmacol Ther. 2015 Sep; 98(3):266-87.
Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN, Pediatric Transporter Working Group. PMID: 26088472; PMCID: PMC4731327.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimals
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Transcriptome-based reconstructions from the murine knockout suggest involvement of the urate transporter, URAT1 (slc22a12), in novel metabolic pathways. Biochem Biophys Rep. 2015 Sep 01; 3:51-61.
Eraly SA, Liu HC, Jamshidi N, Nigam SK. PMID: 26251846; PMCID: PMC4522937.
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PubMed Mentions:
7
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The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells. FASEB J. 2015 May; 29(5):1859-68.
Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. PMID: 25630970; PMCID: PMC4771066.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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The organic anion transporter (OAT) family: a systems biology perspective. Physiol Rev. 2015 Jan; 95(1):83-123.
Nigam SK, Bush KT, Martovetsky G, Ahn SY, Liu HC, Richard E, Bhatnagar V, Wu W. PMID: 25540139; PMCID: PMC4281586.
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PubMed Mentions:
191 Fields:
Translation:
Humans
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What do drug transporters really do? Nat Rev Drug Discov. 2015 Jan; 14(1):29-44.
Nigam SK. PMID: 25475361; PMCID: PMC4750486.
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PubMed Mentions:
220 Fields:
Translation:
HumansAnimals
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Cellular and developmental strategies aimed at kidney tissue engineering. Nephron Exp Nephrol. 2014; 126(2):101.
Martovetsky G, Nigam SK. PMID: 24854650.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Relevance of ureteric bud development and branching to tissue engineering, regeneration and repair in acute and chronic kidney disease. Curr Opin Organ Transplant. 2014 Apr; 19(2):153-61.
Bush KT, Martovetsky G, Nigam SK. PMID: 24503495.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis. Pediatr Nephrol. 2014 Apr; 29(4):727-35.
Nigam SK, Bush KT. PMID: 24488503.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Concise review: can the intrinsic power of branching morphogenesis be used for engineering epithelial tissues and organs? Stem Cells Transl Med. 2013 Dec; 2(12):993-1000.
Nigam SK. PMID: 24191267; PMCID: PMC3841094.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol. 2013 Nov; 24(11):1901-12.
Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK. PMID: 23949796; PMCID: PMC3810086.
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PubMed Mentions:
285 Fields:
Translation:
Humans
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Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters. Mol Pharmacol. 2013 Dec; 84(6):808-23.
Martovetsky G, Tee JB, Nigam SK. PMID: 24038112; PMCID: PMC3834141.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways. Drug Metab Dispos. 2013 Oct; 41(10):1825-34.
Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. PMID: 23920220; PMCID: PMC3781372.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling. Biol Open. 2013; 2(9):952-9.
Tee JB, Choi Y, Dnyanmote A, Decambre M, Ito C, Bush KT, Nigam SK. PMID: 24143282; PMCID: PMC3773342.
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PubMed Mentions:
4 Fields:
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How much do we know about drug handling by SLC and ABC drug transporters in children? Clin Pharmacol Ther. 2013 Jul; 94(1):27-9.
Nigam SK, Bhatnagar V. PMID: 23778708.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue. Neurosci Lett. 2013 Feb 08; 534:133-8.
Nagle MA, Wu W, Eraly SA, Nigam SK. PMID: 23196129; PMCID: PMC3591490.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland. J Biol Chem. 2012 Dec 07; 287(50):42064-70.
Bush KT, Crawford BE, Garner OB, Nigam KB, Esko JD, Nigam SK. PMID: 23060443; PMCID: PMC3516752.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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The storytelling brain. Commentary on "On social attribution: implications of recent cognitive neuroscience research for race, law, and politics". Sci Eng Ethics. 2012 Sep; 18(3):567-71.
Nigam SK. PMID: 22843032.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule. PLoS One. 2012; 7(7):e40796.
Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. PMID: 22808265; PMCID: PMC3396597.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol. 2012 May 15; 302(10):F1293-9.
Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. PMID: 22338083; PMCID: PMC3362066.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Dev Biol. 2012 Apr 01; 364(1):11-21.
Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. PMID: 22290330; PMCID: PMC3310225.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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In vitro culture of embryonic kidney rudiments and isolated ureteric buds. Methods Mol Biol. 2012; 886:13-21.
Zhang X, Bush KT, Nigam SK. PMID: 22639247.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport. Cell Biochem Biophys. 2011 Nov; 61(2):251-9.
Tsigelny IF, Kovalskyy D, Kouznetsova VL, Balinskyi O, Sharikov Y, Bhatnagar V, Nigam SK. PMID: 21499753.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. J Biol Chem. 2011 Sep 09; 286(36):31522-31.
Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK. PMID: 21757732; PMCID: PMC3173137.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury. J Biol Chem. 2011 Jul 29; 286(30):26391-5.
Torres AM, Dnyanmote AV, Bush KT, Wu W, Nigam SK. PMID: 21652719; PMCID: PMC3143602.
View in:
PubMed Mentions:
31 Fields:
Translation:
Animals
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Growth factor-dependent branching of the ureteric bud is modulated by selective 6-O sulfation of heparan sulfate. Dev Biol. 2011 Aug 01; 356(1):19-27.
Shah MM, Sakurai H, Gallegos TF, Sweeney DE, Bush KT, Esko JD, Nigam SK. PMID: 21600196; PMCID: PMC3130836.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Dev Biol. 2011 Jul 15; 355(2):394-403.
Garner OB, Bush KT, Nigam KB, Yamaguchi Y, Xu D, Esko JD, Nigam SK. PMID: 21586278; PMCID: PMC3118867.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1). Bioorg Med Chem. 2011 Jun 01; 19(11):3320-40.
Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK. PMID: 21571536; PMCID: PMC3310230.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). J Proteome Res. 2011 Jun 03; 10(6):2842-51.
Wikoff WR, Nagle MA, Kouznetsova VL, Tsigelny IF, Nigam SK. PMID: 21476605; PMCID: PMC3201759.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
-
Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Mol Pharmacol. 2011 Jul; 80(1):147-54.
Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. PMID: 21493727; PMCID: PMC3127534.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
-
Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis. Mol Pharmacol. 2011 May; 79(5):795-805.
Wu W, Dnyanmote AV, Nigam SK. PMID: 21325265; PMCID: PMC3082935.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
-
Branching morphogenesis: from individual molecules to a systems biology approach: commentary on "Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney" by Perälä et al. Differentiation. 2011 Feb; 81(2):79-80.
Sweeney DE, Gallegos TF, Dnyanmote AV, Zhang X, Nigam SK. PMID: 21168258.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling. J Biol Chem. 2011 Jan 07; 286(1):243-51.
Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, Nigam SK. PMID: 20921221; PMCID: PMC3012981.
View in:
PubMed Mentions:
41 Fields:
Translation:
Animals
-
Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct. Dev Biol. 2010 Nov 15; 347(2):337-47.
Tee JB, Choi Y, Shah MM, Dnyanmote A, Sweeney DE, Gallegos TF, Johkura K, Ito C, Bush KT, Nigam SK. PMID: 20816800; PMCID: PMC2981800.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney. Tissue Eng Part A. 2010 Aug; 16(8):2441-55.
Rosines E, Johkura K, Zhang X, Schmidt HJ, Decambre M, Bush KT, Nigam SK. PMID: 20214453; PMCID: PMC2947461.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice. PLoS One. 2010 May 18; 5(5):e10691.
Crawford BE, Garner OB, Bishop JR, Zhang DY, Bush KT, Nigam SK, Esko JD. PMID: 20502530; PMCID: PMC2872662.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Hs2st mediated kidney mesenchyme induction regulates early ureteric bud branching. Dev Biol. 2010 Mar 15; 339(2):354-65.
Shah MM, Sakurai H, Sweeney DE, Gallegos TF, Bush KT, Esko JD, Nigam SK. PMID: 20059993; PMCID: PMC2834281.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct. Development. 2009 Dec; 136(24):4213-24.
Choi Y, Tee JB, Gallegos TF, Shah MM, Oishi H, Sakurai H, Kitamura S, Wu W, Bush KT, Nigam SK. PMID: 19934016; PMCID: PMC2781055.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Interaction of organic cations with organic anion transporters. J Biol Chem. 2009 Nov 06; 284(45):31422-30.
Ahn SY, Eraly SA, Tsigelny I, Nigam SK. PMID: 19737926; PMCID: PMC2781538.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1330-41.
Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK. PMID: 19726549; PMCID: PMC2781331.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nat Med. 2009 Sep; 15(9):1046-54.
Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. PMID: 19718039; PMCID: PMC2895985.
View in:
PubMed Mentions:
108 Fields:
Translation:
AnimalsCells
-
Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Mol Pharmacol. 2009 Sep; 76(3):481-90.
Ahn SY, Nigam SK. PMID: 19515966; PMCID: PMC2730381.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
-
Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. Am J Physiol Renal Physiol. 2009 Jul; 297(1):F210-7.
Wu W, Kitamura S, Truong DM, Rieg T, Vallon V, Sakurai H, Bush KT, Vera DR, Ross RS, Nigam SK. PMID: 19439520; PMCID: PMC2711709.
View in:
PubMed Mentions:
40 Fields:
Translation:
Animals
-
Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiol Genomics. 2009 Jul 09; 38(2):116-24.
Wu W, Baker ME, Eraly SA, Bush KT, Nigam SK. PMID: 19417012; PMCID: PMC2712220.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Analysis of metagene portraits reveals distinct transitions during kidney organogenesis. Sci Signal. 2008 Dec 09; 1(49):ra16.
Tsigelny IF, Kouznetsova VL, Sweeney DE, Wu W, Bush KT, Nigam SK. PMID: 19066399; PMCID: PMC3016920.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
How does the ureteric bud branch? J Am Soc Nephrol. 2009 Jul; 20(7):1465-9.
Nigam SK, Shah MM. PMID: 19056872.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
-
Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function. J Bioinform Comput Biol. 2008 Oct; 6(5):885-904.
Tsigelny IF, Greenberg J, Kouznetsova V, Nigam SK. PMID: 18942157; PMCID: PMC2676871.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology. Organogenesis. 2008 Jul; 4(3):137-43.
Nigam SK, Wu W, Bush KT. PMID: 19279725; PMCID: PMC2634587.
View in:
PubMed Mentions:
6 Fields:
-
Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol. 2008 Sep; 19(9):1732-40.
Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. PMID: 18508962; PMCID: PMC2518443.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics. 2008 Apr 22; 33(2):180-92.
Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. PMID: 18270321; PMCID: PMC3016923.
View in:
PubMed Mentions:
93 Fields:
Translation:
Animals
-
MAPAS: a tool for predicting membrane-contacting protein surfaces. Nat Methods. 2008 Feb; 5(2):119.
Sharikov Y, Walker RC, Greenberg J, Kouznetsova V, Nigam SK, Miller MA, Masliah E, Tsigelny IF. PMID: 18235431.
View in:
PubMed Mentions:
11 Fields:
Translation:
Cells
-
Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F867-73.
Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK. PMID: 18216144.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
-
Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. J Biol Chem. 2008 Mar 28; 283(13):8654-63.
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. PMID: 18174163; PMCID: PMC2417182.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
-
Staged in vitro reconstitution and implantation of engineered rat kidney tissue. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20938-43.
Rosines E, Sampogna RV, Johkura K, Vaughn DA, Choi Y, Sakurai H, Shah MM, Nigam SK. PMID: 18087037; PMCID: PMC2409245.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct. J Am Soc Nephrol. 2007 Dec; 18(12):3147-55.
Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK. PMID: 18003772.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissues. Biomaterials. 2007 Nov; 28(32):4806-17.
Rosines E, Schmidt HJ, Nigam SK. PMID: 17706761; PMCID: PMC2700261.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues. Nat Clin Pract Nephrol. 2007 Aug; 3(8):443-8.
Nigam SK, Bush KT, Bhatnagar V. PMID: 17653123.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
-
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem. 2007 Aug 17; 282(33):23841-53.
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. PMID: 17553798; PMCID: PMC3812435.
View in:
PubMed Mentions:
48 Fields:
Translation:
Cells
-
The developmental nephrome: systems biology in the developing kidney. Curr Opin Nephrol Hypertens. 2007 Jan; 16(1):3-9.
Monte JC, Sakurai H, Bush KT, Nigam SK. PMID: 17143064.
View in:
PubMed Mentions:
14 Fields:
Translation:
Animals
-
Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development. Differentiation. 2006 Dec; 74(9-10):638-47.
Meyer TN, Schwesinger C, Sampogna RV, Vaughn DA, Stuart RO, Steer DL, Bush KT, Nigam SK. PMID: 17177859.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
-
Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochem Biophys Res Commun. 2006 Dec 29; 351(4):872-6.
Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, Nigam SK. PMID: 17094945; PMCID: PMC1810587.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system. Dev Biol. 2006 Oct 15; 298(2):571-84.
Bush KT, Vaughn DA, Li X, Rosenfeld MG, Rose DW, Mendoza SA, Nigam SK. PMID: 16934795.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Benign vascular tumors of female genital tract. Int J Gynecol Cancer. 2006 May-Jun; 16(3):1195-200.
Gupta R, Singh S, Nigam S, Khurana N. PMID: 16803506.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). J Hum Genet. 2006; 51(6):575-580.
Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. PMID: 16648942.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev Biol. 2006 Jul 15; 295(2):473-85.
Maeshima A, Vaughn DA, Choi Y, Nigam SK. PMID: 16643884.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney Int. 2006 Mar; 69(5):837-45.
Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. PMID: 16518343; PMCID: PMC2825705.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem. 2006 Feb 24; 281(8):5072-83.
Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. PMID: 16354673.
View in:
PubMed Mentions:
104 Fields:
Translation:
AnimalsCells
-
Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney. J Am Soc Nephrol. 2006 Jan; 17(1):188-98.
Maeshima A, Sakurai H, Nigam SK. PMID: 16338966.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
-
Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)]. Kidney Int. 2005 Oct; 68(4):1491-9.
Xu G, Bhatnagar V, Wen G, Hamilton BA, Eraly SA, Nigam SK. PMID: 16164626.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Heregulin induces glial cell line-derived neurotrophic growth factor-independent, non-branching growth and differentiation of ureteric bud epithelia. J Biol Chem. 2005 Dec 23; 280(51):42181-7.
Sakurai H, Bush KT, Nigam SK. PMID: 16183643.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Implications of gene networks for understanding resilience and vulnerability in the kidney branching program. Physiology (Bethesda). 2004 Dec; 19:339-47.
Sampogna RV, Nigam SK. PMID: 15546851.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
-
Unilateral gestational macromastia--a rare disorder. Malays J Pathol. 2004 Dec; 26(2):125-8.
Sharma K, Nigam S, Khurana N, Chaturvedi KU. PMID: 16329566.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney. Dev Biol. 2004 Nov 01; 275(1):44-67.
Meyer TN, Schwesinger C, Bush KT, Stuart RO, Rose DW, Shah MM, Vaughn DA, Steer DL, Nigam SK. PMID: 15464572.
View in:
PubMed Mentions:
53 Fields:
Translation:
Animals
-
Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa. Biochem Biophys Res Commun. 2004 Oct 15; 323(2):429-36.
Monte JC, Nagle MA, Eraly SA, Nigam SK. PMID: 15369770.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
-
Tunicamycin preserves intercellular junctions, cytoarchitecture, and cell-substratum interactions in ATP-depleted epithelial cells. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):223-31.
George SK, Meyer TN, Abdeen O, Bush KT, Nigam SK. PMID: 15313195.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney. Dev Biol. 2004 Aug 15; 272(2):310-27.
Steer DL, Shah MM, Bush KT, Stuart RO, Sampogna RV, Meyer TN, Schwesinger C, Bai X, Esko JD, Nigam SK. PMID: 15282150.
View in:
PubMed Mentions:
33 Fields:
Translation:
Animals
-
Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiol Genomics. 2004 Jun 17; 18(1):12-24.
Eraly SA, Monte JC, Nigam SK. PMID: 15054140.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
-
Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis. Am J Physiol Renal Physiol. 2004 Oct; 287(4):F602-11.
Chen D, Roberts R, Pohl M, Nigam S, Kreidberg J, Wang Z, Heino J, Ivaska J, Coffa S, Harris RC, Pozzi A, Zent R. PMID: 15187002.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
-
Branching morphogenesis and kidney disease. Development. 2004 Apr; 131(7):1449-62.
Shah MM, Sampogna RV, Sakurai H, Bush KT, Nigam SK. PMID: 15023929.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
-
The molecular pharmacology of organic anion transporters: from DNA to FDA? Mol Pharmacol. 2004 Mar; 65(3):479-87.
Eraly SA, Bush KT, Sampogna RV, Bhatnagar V, Nigam SK. PMID: 14978224.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
-
TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud. Dev Biol. 2004 Feb 15; 266(2):285-98.
Bush KT, Sakurai H, Steer DL, Leonard MO, Sampogna RV, Meyer TN, Schwesinger C, Qiao J, Nigam SK. PMID: 14738877.
View in:
PubMed Mentions:
54 Fields:
Translation:
Animals
-
Complex dynamics of chaperone-protein interactions under cellular stress. Cell Biochem Biophys. 2004; 40(3):263-76.
Tsigelny IF, Nigam SK. PMID: 15211027.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Developmental approaches to kidney tissue engineering. Am J Physiol Renal Physiol. 2004 Jan; 286(1):F1-7.
Steer DL, Nigam SK. PMID: 14656756.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
-
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. Am J Physiol Renal Physiol. 2004 May; 286(5):F972-8.
Sykes D, Sweet DH, Lowes S, Nigam SK, Pritchard JB, Miller DS. PMID: 15075193.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Changes in gene expression patterns in the ureteric bud and metanephric mesenchyme in models of kidney development. Kidney Int. 2003 Dec; 64(6):1997-2008.
Stuart RO, Bush KT, Nigam SK. PMID: 14633122.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
-
From the ureteric bud to the penome. Kidney Int. 2003 Dec; 64(6):2320-2.
Nigam SK. PMID: 14633158.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20; 426(6964):247-54.
Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. PMID: 14628042.
View in:
PubMed Mentions:
288 Fields:
Translation:
AnimalsCells
-
Novel aspects of renal organic anion transporters. Curr Opin Nephrol Hypertens. 2003 Sep; 12(5):551-8.
Eraly SA, Blantz RC, Bhatnagar V, Nigam SK. PMID: 12920404.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
-
Biochemical processing of E-cadherin under cellular stress. Biochem Biophys Res Commun. 2003 Jul 25; 307(2):215-23.
Keller SH, Nigam SK. PMID: 12859942.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis. Biochem Biophys Res Commun. 2003 Jul 04; 306(3):623-8.
Li Z, Stuart RO, Eraly SA, Gittes G, Beier DR, Nigam SK. PMID: 12810064.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochem Biophys Res Commun. 2003 Jan 10; 300(2):333-42.
Eraly SA, Hamilton BA, Nigam SK. PMID: 12504088.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
A strategy for in vitro propagation of rat nephrons. Kidney Int. 2002 Dec; 62(6):1958-65.
Steer DL, Bush KT, Meyer TN, Schwesinger C, Nigam SK. PMID: 12427120.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochem Biophys Res Commun. 2002 Oct 11; 297(5):1159-66.
Eraly SA, Nigam SK. PMID: 12372408.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem. 2002 Jul 26; 277(30):26934-43.
Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. PMID: 12011098.
View in:
PubMed Mentions:
101 Fields:
Translation:
Animals
-
Toward an etiological classification of developmental disorders of the kidney and upper urinary tract. Kidney Int. 2002 Jan; 61(1):10-9.
Pohl M, Bhatnagar V, Mendoza SA, Nigam SK. PMID: 11786080.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
-
Characterization of Aspergillus fumigatus protein disulfide isomerase family gene. Gene. 2001 Dec 27; 281(1-2):143-50.
Nigam S, Sarma PV, Ghosh PC, Sarma PU. PMID: 11750136.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis. Mech Dev. 2001 Dec; 109(2):123-35.
Qiao J, Bush KT, Steer DL, Stuart RO, Sakurai H, Wachsman W, Nigam SK. PMID: 11731227.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis. Am J Physiol Renal Physiol. 2001 Dec; 281(6):F1148-56.
Stuart RO, Pavlova A, Beier D, Li Z, Krijanovski Y, Nigam SK. PMID: 11704567.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12509-14.
Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. PMID: 11606725; PMCID: PMC60084.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis. Development. 2001 Sep; 128(17):3283-93.
Sakurai H, Bush KT, Nigam SK. PMID: 11546745.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene. J Biol Chem. 2001 Nov 16; 276(46):42753-60.
Shankaranarayanan P, Chaitidis P, Kühn H, Nigam S. PMID: 11509556.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
The organic anion transporter family: from physiology to ontogeny and the clinic. Am J Physiol Renal Physiol. 2001 Aug; 281(2):F197-205.
Sweet DH, Bush KT, Nigam SK. PMID: 11457711.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
Expanding role of G proteins in tight junction regulation: Galpha(s) stimulates TJ assembly. Biochem Biophys Res Commun. 2001 Jul 13; 285(2):250-6.
Saha C, Nigam SK, Denker BM. PMID: 11444833.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Changes in global gene expression patterns during development and maturation of the rat kidney. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5649-54.
Stuart RO, Bush KT, Nigam SK. PMID: 11331749; PMCID: PMC33267.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity. J Biol Chem. 2001 Jun 22; 276(25):22048-55.
Meyer TN, Schwesinger C, Ye J, Denker BM, Nigam SK. PMID: 11294856.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
-
Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Mol Cell Biol. 2001 Feb; 21(3):765-70.
Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. PMID: 11154264; PMCID: PMC86668.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Nongestational pure ovarian choriocarcinoma with contralateral teratoma. Gynecol Oncol. 2001 Feb; 80(2):262-6.
Goswami D, Sharma K, Zutshi V, Tempe A, Nigam S. PMID: 11161870.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Matrix metalloproteinases and their inhibitors regulate in vitro ureteric bud branching morphogenesis. Am J Physiol Renal Physiol. 2000 Nov; 279(5):F891-900.
Pohl M, Sakurai H, Bush KT, Nigam SK. PMID: 11053050.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Genesis and reversal of the ischemic phenotype in epithelial cells. J Clin Invest. 2000 Sep; 106(5):621-6.
Bush KT, Keller SH, Nigam SK. PMID: 10974012; PMCID: PMC381296.
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PubMed Mentions:
17 Fields:
Translation:
Cells
-
A role for Timeless in epithelial morphogenesis during kidney development. Proc Natl Acad Sci U S A. 2000 Aug 29; 97(18):10038-43.
Li Z, Stuart RO, Qiao J, Pavlova A, Bush KT, Pohl M, Sakurai H, Nigam SK. PMID: 10963667; PMCID: PMC27664.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells. Dev Biol. 2000 Aug 15; 224(2):312-25.
Pohl M, Sakurai H, Stuart RO, Nigam SK. PMID: 10926769.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Selective degradation of E-cadherin and dissolution of E-cadherin-catenin complexes in epithelial ischemia. Am J Physiol Renal Physiol. 2000 May; 278(5):F847-52.
Bush KT, Tsukamoto T, Nigam SK. PMID: 10807598.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr; 278(4):F635-43.
Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK. PMID: 10751225.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Branching morphogenesis during kidney development. Annu Rev Physiol. 2000; 62:595-620.
Pohl M, Stuart RO, Sakurai H, Nigam SK. PMID: 10845104.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable. Am J Physiol Renal Physiol. 2000 Jan; 278(1):F1-F12.
Lieberthal W, Nigam SK. PMID: 10644651.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Evolution of gene expression patterns in a model of branching morphogenesis. Am J Physiol. 1999 10; 277(4):F650-63.
Pavlova A, Stuart RO, Pohl M, Nigam SK. PMID: 10516290.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
A role for intracellular calcium in tight junction reassembly after ATP depletion-repletion. Am J Physiol. 1999 10; 277(4):F524-32.
Ye J, Tsukamoto T, Sun A, Nigam SK. PMID: 10516276.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Cell-cell dissociation upon epithelial cell scattering requires a step mediated by the proteasome. J Biol Chem. 1999 Aug 27; 274(35):24579-84.
Tsukamoto T, Nigam SK. PMID: 10455122.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Pretreatment with inducers of ER molecular chaperones protects epithelial cells subjected to ATP depletion. Am J Physiol. 1999 08; 277(2):F211-8.
Bush KT, George SK, Zhang PL, Nigam SK. PMID: 10444575.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney. Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13):7330-5.
Qiao J, Sakurai H, Nigam SK. PMID: 10377414; PMCID: PMC22085.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
-
Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. Am J Physiol. 1999 05; 276(5):F737-50.
Tsukamoto T, Nigam SK. PMID: 10330056.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
-
Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells. Am J Physiol. 1999 04; 276(4):F581-8.
O'Rourke DA, Sakurai H, Spokes K, Kjelsberg C, Takahashi M, Nigam S, Cantley L. PMID: 10198418.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Less degradation, more shock, please. Gastroenterology. 1999 Apr; 116(4):994-5.
Bush KT, Nigam SK. PMID: 10092324.
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PubMed Mentions: Fields:
Translation:
Animals
-
Oxylipin formation in fungi: biotransformation of arachidonic acid to 3-hydroxy-5,8-tetradecadienoic acid by Mucor genevensis. Biochem Biophys Res Commun. 1998 Dec 30; 253(3):703-6.
Pohl CH, Botha A, Kock JL, Coetzee DJ, Botes PJ, Schewe T, Nigam S. PMID: 9918790.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsPHPublic Health
-
Folding of secretory and membrane proteins. N Engl J Med. 1998 Dec 03; 339(23):1688-95.
Kuznetsov G, Nigam SK. PMID: 9834307.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Acute renal failure. I. Relative importance of proximal vs. distal tubular injury. Am J Physiol. 1998 11; 275(5):F623-31.
Lieberthal W, Nigam SK. PMID: 9815122.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimals
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The actin cytoskeleton and integrin expression in the recovery of cell adhesion after oxidant stress to a proximal tubule cell line (JTC-12). J Am Soc Nephrol. 1998 Oct; 9(10):1787-97.
Nigam S, Weston CE, Liu CH, Simon EE. PMID: 9773779.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions. J Biol Chem. 1998 Aug 21; 273(34):21629-33.
Saha C, Nigam SK, Denker BM. PMID: 9705295.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
In vitro branching tubulogenesis: implications for developmental and cystic disorders, nephron number, renal repair, and nephron engineering. Kidney Int. 1998 Jul; 54(1):14-26.
Sakurai H, Nigam SK. PMID: 9648059.
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PubMed Mentions:
25 Fields:
Translation:
Animals
-
Molecular structure and assembly of the tight junction. Am J Physiol. 1998 01; 274(1):F1-9.
Denker BM, Nigam SK. PMID: 9458817.
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PubMed Mentions:
118 Fields:
Translation:
HumansAnimalsCells
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EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney. Am J Physiol. 1997 Sep; 273(3 Pt 2):F463-72.
Sakurai H, Tsukamoto T, Kjelsberg CA, Cantley LG, Nigam SK. PMID: 9321921.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
-
Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly. J Biol Chem. 1997 Jun 27; 272(26):16133-9.
Tsukamoto T, Nigam SK. PMID: 9195909.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
-
An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6279-84.
Sakurai H, Barros EJ, Tsukamoto T, Barasch J, Nigam SK. PMID: 9177208; PMCID: PMC21040.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance. J Biol Chem. 1997 Apr 04; 272(14):9086-92.
Bush KT, Goldberg AL, Nigam SK. PMID: 9083035.
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PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
-
Distribution and developmentally regulated expression of murine polycystin. Am J Physiol. 1997 Apr; 272(4 Pt 2):F451-9.
Geng L, Segal Y, Pavlova A, Barros EJ, Löhning C, Lu W, Nigam SK, Frischauf AM, Reeders ST, Zhou J. PMID: 9140045.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
-
Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. J Biol Chem. 1997 Mar 07; 272(10):6471-8.
Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. PMID: 9045672.
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PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
-
Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands. Am J Physiol. 1997 Feb; 272(2 Pt 2):F222-8.
Kjelsberg C, Sakurai H, Spokes K, Birchmeier C, Drummond I, Nigam S, Cantley LG. PMID: 9124399.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Multiple molecular chaperones complex with misfolded large oligomeric glycoproteins in the endoplasmic reticulum. J Biol Chem. 1997 Jan 31; 272(5):3057-63.
Kuznetsov G, Chen LB, Nigam SK. PMID: 9006956.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Transforming growth factor-beta selectively inhibits branching morphogenesis but not tubulogenesis. Am J Physiol. 1997 Jan; 272(1 Pt 2):F139-46.
Sakurai H, Nigam SK. PMID: 9039060.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis. J Biol Chem. 1996 Oct 18; 271(42):25750-3.
Denker BM, Saha C, Khawaja S, Nigam SK. PMID: 8824202.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8584-9.
Kuznetsov G, Bush KT, Zhang PL, Nigam SK. PMID: 8710914; PMCID: PMC38716.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Selective amplification of protein-coding regions of large sets of genes using statistically designed primer sets. Nat Biotechnol. 1996 Jul; 14(7):857-61.
López-Nieto CE, Nigam SK. PMID: 9631010.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores. J Biol Chem. 1996 Jun 07; 271(23):13636-41.
Stuart RO, Sun A, Bush KT, Nigam SK. PMID: 8662885.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney. J Biol Chem. 1995 Dec 08; 270(49):29365-71.
You G, Lee WS, Barros EJ, Kanai Y, Huo TL, Khawaja S, Wells RG, Nigam SK, Hediger MA. PMID: 7493971.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Epithelial tubulogenesis through branching morphogenesis: relevance to collecting system development. J Am Soc Nephrol. 1995 Oct; 6(4):1151-9.
Stuart RO, Barros EJ, Ribeiro E, Nigam SK. PMID: 8589281.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Development of the tubular nephron. Semin Nephrol. 1995 Jul; 15(4):315-26.
Stuart RO, Nigam SK. PMID: 7569411.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Regulated assembly of tight junctions by protein kinase C. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):6072-6.
Stuart RO, Nigam SK. PMID: 7597083; PMCID: PMC41644.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
-
HGF-mediated chemotaxis and tubulogenesis require activation of the phosphatidylinositol 3-kinase. Am J Physiol. 1995 Jun; 268(6 Pt 2):F1211-7.
Derman MP, Cunha MJ, Barros EJ, Nigam SK, Cantley LG. PMID: 7611461.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Differential tubulogenic and branching morphogenetic activities of growth factors: implications for epithelial tissue development. Proc Natl Acad Sci U S A. 1995 May 09; 92(10):4412-6.
Barros EJ, Santos OF, Matsumoto K, Nakamura T, Nigam SK. PMID: 7753820; PMCID: PMC41954.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Determinants of branching tubulogenesis. Curr Opin Nephrol Hypertens. 1995 May; 4(3):209-14.
Nigam SK. PMID: 7648213.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. J Cell Biol. 1994 Dec; 127(6 Pt 2):1783-7.
Rosen EM, Nigam SK, Goldberg ID. PMID: 7806559; PMCID: PMC2120304.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum. Biochem J. 1994 Nov 01; 303 ( Pt 3):705-8.
Bush KT, Hendrickson BA, Nigam SK. PMID: 7526846; PMCID: PMC1137603.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Triterpenoid saponins from Madhuca butyracea. Phytochemistry. 1994 Oct; 37(3):827-9.
Li XC, Liu YQ, Wang DZ, Yang CR, Nigam SK, Misra G. PMID: 7765693.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Characterization of integrins in cultured human renal cortical tubule epithelial cells. Am J Physiol. 1994 Oct; 267(4 Pt 2):F612-23.
Simon EE, Liu CH, Das M, Nigam S, Broekelmann TJ, McDonald JA. PMID: 7943359.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Epithelial inositol 1,4,5-trisphosphate receptors. Multiplicity of localization, solubility, and isoforms. J Biol Chem. 1994 Sep 23; 269(38):23694-9.
Bush KT, Stuart RO, Li SH, Moura LA, Sharp AH, Ross CA, Nigam SK. PMID: 8089140.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Several endoplasmic reticulum stress proteins, including ERp72, interact with thyroglobulin during its maturation. J Biol Chem. 1994 Sep 16; 269(37):22990-5.
Kuznetsov G, Chen LB, Nigam SK. PMID: 7916014.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells. Am J Physiol. 1994 Aug; 267(2 Pt 2):F271-80.
Cantley LG, Barros EJ, Gandhi M, Rauchman M, Nigam SK. PMID: 8067388.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
Critical role for intracellular calcium in tight junction biogenesis. J Cell Physiol. 1994 Jun; 159(3):423-33.
Stuart RO, Sun A, Panichas M, Hebert SC, Brenner BM, Nigam SK. PMID: 8188760.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Involvement of hepatocyte growth factor in kidney development. Dev Biol. 1994 Jun; 163(2):525-9.
Santos OF, Barros EJ, Yang XM, Matsumoto K, Nakamura T, Park M, Nigam SK. PMID: 8200486.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily. J Biol Chem. 1994 Jan 21; 269(3):1744-9.
Nigam SK, Goldberg AL, Ho S, Rohde MF, Bush KT. PMID: 8294423.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
-
Characterization and crystallization of recombinant human neurotrophin-4. J Biol Chem. 1994 Jan 07; 269(1):755-9.
Fandl JP, Tobkes NJ, McDonald NQ, Hendrickson WA, Ryan TE, Nigam S, Acheson A, Cudny H, Panayotatos N. PMID: 8276879.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-beta. Dev Biol. 1993 Dec; 160(2):293-302.
Santos OF, Nigam SK. PMID: 8253265.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
-
Modulation of HGF-induced tubulogenesis and branching by multiple phosphorylation mechanisms. Dev Biol. 1993 Oct; 159(2):535-48.
Santos OF, Moura LA, Rosen EM, Nigam SK. PMID: 8405677.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse. Am J Physiol. 1993 Sep; 265(3 Pt 2):F416-24.
Rauchman MI, Nigam SK, Delpire E, Gullans SR. PMID: 8214101.
View in:
PubMed Mentions:
116 Fields:
Translation:
AnimalsCells
-
Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J. 1993 Sep 01; 294 ( Pt 2):511-5.
Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ. PMID: 8373365; PMCID: PMC1134484.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Evidence for the presence of specific high affinity cytosolic binding sites for platelet-activating factor in human neutrophils. Biochem Biophys Res Commun. 1993 Jan 15; 190(1):162-6.
Svetlov S, Nigam S. PMID: 8380690.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Enhancement by staurosporine of platelet-activating factor formation in N-formyl peptide-challenged human neutrophils is mediated by intracellular platelet-activating factor binding sites. Biochem Biophys Res Commun. 1992 Dec 15; 189(2):771-6.
Müller S, Nigam S. PMID: 1335246.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Toward an understanding of epithelial morphogenesis in health and disease. Curr Opin Nephrol Hypertens. 1992 Dec; 1(2):187-91.
Nigam SK, Brenner BM. PMID: 1345616.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Triterpenoidal saponins from Madhuca butyracea. Phytochemistry. 1992 Sep; 31(9):3169-72.
Nigam SK, Li XC, Wang DZ, Misra G, Yang CR. PMID: 1368412.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Changes in intracellular calcium during the development of epithelial polarity and junctions. Proc Natl Acad Sci U S A. 1992 Jul 01; 89(13):6162-6.
Nigam SK, Rodriguez-Boulan E, Silver RB. PMID: 1631104; PMCID: PMC402142.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells. Biochem Biophys Res Commun. 1991 Dec 16; 181(2):548-53.
Nigam SK, Denisenko N, Rodriguez-Boulan E, Citi S. PMID: 1755836.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
In Vitro Production of Essential Oil from Proliferating Shoots of Rosmarinus officinalis1. Planta Med. 1991 Apr; 57(2):122-4.
Jain M, Banerji R, Nigam SK, Scheffer JJ, Chaturvedi HC. PMID: 17226137.
View in:
PubMed Mentions: Fields:
-
Lipoxins trigger the release but not the oxygenation of arachidonic acid in human neutrophils: dissociation between lipid remodeling and adhesion. Adv Prostaglandin Thromboxane Leukot Res. 1991; 21B:553-6.
Fiore S, Nigam S, Serhan CN. PMID: 1825377.
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PubMed Mentions: Fields:
Translation:
HumansCells
-
Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid from human neutrophils. Biochem Biophys Res Commun. 1990 Sep 28; 171(3):944-8.
Nigam S, Nodes S, Cichon G, Corey EJ, Pace-Asciak CR. PMID: 2171511.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Subcellular distribution of calcium-binding proteins and a calcium-ATPase in canine pancreas. J Cell Biol. 1990 Jul; 111(1):197-200.
Nigam SK, Towers T. PMID: 2142161; PMCID: PMC2116152.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Lipoxin A4 and lipoxin B4 stimulate the release but not the oxygenation of arachidonic acid in human neutrophils: dissociation between lipid remodeling and adhesion. J Cell Physiol. 1990 Jun; 143(3):512-23.
Nigam S, Fiore S, Luscinskas FW, Serhan CN. PMID: 2162850.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Subcellular distribution of small GTP binding proteins in pancreas: identification of small GTP binding proteins in the rough endoplasmic reticulum. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1296-9.
Nigam SK. PMID: 2106133; PMCID: PMC53461.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Cyclic AMP-dependent protein kinase in canine pancreatic rough endoplasmic reticulum. J Biol Chem. 1989 Oct 05; 264(28):16927-32.
Nigam SK, Blobel G. PMID: 2550466.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Identification of a G protein in rough endoplasmic reticulum of canine pancreas. J Biol Chem. 1988 Nov 05; 263(31):16352-7.
Audigier Y, Nigam SK, Blobel G. PMID: 3141406.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells