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David Smith

Title(s)Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0679
La Jolla CA 92093
Phone858-642-1620
ORCID ORCID Icon0000-0003-3603-1733 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego School of Medicine, La Jolla, CAM.A.S. Clinical Research2005Infectious Diseases
    University of California, San Diego School of Medicine, La Jolla, CAFellow2003Infectious Diseases
    University of California, San Diego School of Medicine, La Jolla, CAChief Resident2000Internal Medicine
    University of California, San Diego School of Medicine, La Jolla, CAIntern and Resident1999Internal Medicine
    East Tennessee State University College of Medicine, Johnson City, TNM.D.1996Medicine
    University of Tennessee at Chattanooga, Chattanooga, TNB.S. summa cum laude1992Biology
    Collapse Awards and Honors
    East Tennessee State University1995AOA
    East Tennessee State University1996Dean Scholarship Award
    San Diego LGBT Center2001Men’s Volunteer of the Year
    San Diego LGBT Center2005Transgender Community Award
    San Diego Metropolitan Magazine200840 under 40
    County of San Diego2009Dr. Truax Award for HIV Service
    National Institute for Drug Abuse2012Avant Garde Award for HIV
    American College of Physicians2014Fellow
    American Society of Clinical Investigation2015Fellow
    Infectious Disease Society of America2018Fellow

    Collapse Overview 
    Collapse Overview
    Davey Smith, MD, MAS, is an infectious disease specialist and translational research virologist. In his translational research, he uses basic science techniques to answer clinically relevant questions. Dr. Smith's primary research involves both figuring out how to stop the transmission of HIV and curing HIV, and he has published over 200 scientific publications in these areas. In 2010, Dr. Smith was named HIV Researcher of the Year by the HIV Medical Association, and he became the co-director and principal investigator of the San Diego Center for AIDS Research (CFAR) in 2016.

    Since the outbreak of SARS-CoV-2 in 2019, Dr. Smith has been actively engaged in the international effort to find safe and effective treatments. In particular, he is the international protocol chair for the ACTIV-2 treatment study, which is a part of the US government’s Operation Warp Speed. This study is designed to find effective therapies for persons with early COVID-19.

    Dr. Smith graduated from East Tennessee State University School of Medicine in 1996. He completed his internship, residency and chief residency in Internal Medicine at UC San Diego and stayed to complete his fellowship in Infectious Diseases. He joined the UC San Diego faculty in 2003, and was promoted to full professor in 2012. In 2017, he was promoted to Head of the Division of Infectious Diseases and Global Public Health at UC San Diego. In 2020, he was appointed the Florence Seeley Riford Chair in AIDS Research at UC San Diego. He has been elected as a fellow to the American Society of Clinical Investigation, American College of Physicians, and Infectious Diseases Society of America.

    Collapse Research 
    Collapse Research Activities and Funding
    Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/
    NIH/NIAID UM1AI068636May 18, 2020 - Nov 30, 2020
    Role: Co-Investigator
    Pooled Testing for SARS-CoV-2 to Screen HIV Providers to Protect HIV Patients
    University of California Office of the President UCOP R00RG2455May 1, 2020 - Oct 31, 2020
    Role: PI
    Role Description: The goal is to develop a cost effective daily screening approach to detect SARS-CoV-2 among asymptomatic care research personnel and protect the staff and participants who volunteer for research studies from getting infected from an asymptomatic SARS-CoV-2 positive individual.
    Dynamics and Sources of SARS-CoV-2 shedding to Limit SARS-CoV-2 Transmission
    University of California Office of the President UCOP R00RG2725May 1, 2020 - Oct 31, 2020
    Role: Co-Investigator
    Role Description: The goal is to determine the biological source and dynamics of SARS-CoV-2 viral shedding in key body fluids in symptomatic and asymptomatic participants with confirmed SARS-CoV-2 infection
    Opioid Impacts on T Cell Pathways and Epigenetics to Modulate HIV Integration, Latency and Reservoirs.
    NIH/NIDA R61DA047039Sep 30, 2018 - Jun 30, 2021
    Role: Principal Investigator
    Revealing Reservoirs during Rebound (R3)
    NIH/NIAID P01AI131385Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Perturbing the HIV Reservoir with Immune Stimulation
    NIH/NIAID R01AI118422Feb 1, 2016 - Jan 31, 2021
    Role: Principal Investigator
    Characterizing proviral populations in brain tissues
    NIH/NIDA R33DA041007Sep 15, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Characterizing proviral populations in brain tissues
    NIH/NIDA R21DA041007Sep 15, 2015 - Jul 31, 2018
    Role: Principal Investigator
    High-throughput Deep Sequencing Assay to Reliably Measure the HIV Reservoir during Antiretroviral Therapy
    NIH/NIAID R01AI120009Jul 1, 2015 - Dec 31, 2019
    Role: Principal Investigator
    Combined Testing to Identify Virologic Failure and HIV-1 Drug Resistance
    NIH/NIBIB R03EB015365Sep 30, 2014 - Aug 31, 2016
    Role: Principal Investigator
    Molecular Epidemiology for HIV Prevention for Drug Users and Other Risk Groups
    NIH/NIDA DP1DA034978Aug 1, 2012 - Jul 31, 2017
    Role: Principal Investigator
    Mentoring Translational Research in HIV
    NIH/NIAID K24AI100665May 1, 2012 - Apr 30, 2022
    Role: Principal Investigator
    Effects of Host and Viral Aging on Neurocognition
    NIH/NIMH R01MH097520Mar 5, 2012 - Dec 31, 2016
    Role: Principal Investigator
    Pooled Nucleic Acid Testing to Identify Antiretroviral Treatment Failure in India
    NIH/NIAID R21AI080353Apr 1, 2011 - Sep 30, 2013
    Role: Principal Investigator
    Interplay of B cells and HIV Leading to Broad Neutralizing Antibody Responses
    NIH U19AI090970Sep 1, 2010 - Aug 31, 2015
    Role: Co-Investigator
    A Multi-Site Investigation into the Effect of HIV Clade on Neurocognition
    NIH/NIMH R01MH083552Sep 8, 2008 - Aug 31, 2014
    Role: Principal Investigator
    Detection and Characterization of HIV-1 Intraclade Dual Infection
    NIH/NIAID R21AI077304Mar 1, 2008 - Feb 28, 2011
    Role: Principal Investigator
    Compartmentalization of HIV within the genital tract
    NIH/NIAID K23AI055276Jul 1, 2003 - Apr 30, 2008
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH/NIMH P30MH062512Apr 24, 2001 - Nov 30, 2005
    Role: Co-Investigator
    Center for AIDS Research
    NIH/NIAID P30AI036214Apr 1, 1997 - May 31, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. High Prevalence of HIV-1 Drug Resistance and Dynamics of Transmission Among High-Risk Populations in Port-au-Prince, Haiti. J Acquir Immune Defic Syndr. 2020 Dec 01; 85(4):416-422. Jean Louis F, Domercant JW, Ignacio C, Gianella S, Galbaud G, Leonard M, Smith DM, Chaillon A. PMID: 33136738.
      View in: PubMed   Mentions:    Fields:    
    2. "[It] is now my responsibility to fulfill that wish:" Clinical and rapid autopsy staff members' experiences and perceptions of HIV reservoir research at the end of life. PLoS One. 2020; 15(11):e0242420. Perry KE, Taylor J, Patel H, Javadi SS, Mathur K, Kaytes A, Concha-Garcia S, Little S, Smith D, Gianella S, Dubé K. PMID: 33206710.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Comparative Circulation Dynamics of the Five Main HIV Types in China. J Virol. 2020 Nov 09; 94(23). Vrancken B, Zhao B, Li X, Han X, Liu H, Zhao J, Zhong P, Lin Y, Zai J, Liu M, Smith DM, Dellicour S, Chaillon A. PMID: 32938762.
      View in: PubMed   Mentions:    Fields:    
    4. Grindr Users Take More Risks, but Are More Open to Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis: Could This Dating App Provide a Platform for HIV Prevention Outreach? Clin Infect Dis. 2020 Oct 23; 71(7):e135-e140. Hoenigl M, Little SJ, Grelotti D, Skaathun B, Wagner GA, Weibel N, Stockman JK, Smith DM. PMID: 31677383.
      View in: PubMed   Mentions: 3     Fields:    
    5. Quantifying Public Interest in Police Reforms by Mining Internet Search Data Following George Floyd's Death. J Med Internet Res. 2020 10 21; 22(10):e22574. Ayers JW, Althouse BM, Poliak A, Leas EC, Nobles AL, Dredze M, Smith D. PMID: 33084578.
      View in: PubMed   Mentions:    Fields:    
    6. Dynamics and Dispersal of Local HIV Epidemics Within San Diego and Across The San Diego-Tijuana Border. Clin Infect Dis. 2020 Oct 20. Vrancken B, Mehta SR, Ávila-Ríos S, García-Morales C, Tapia-Trejo D, Reyes-Terán G, Navarro-Álvarez S, Little SJ, Hoenigl M, Pines HA, Patterson T, Strathdee SA, Smith DM, Dellicour S, Chaillon A. PMID: 33079188.
      View in: PubMed   Mentions:    Fields:    
    7. In vitro anthelmintic activity of Psidium guajava hydroalcoholic extract against gastro-intestinal sheep nematodes. An Acad Bras Cienc. 2020; 92(suppl 2):e20190074. Silva LP, Debiage RR, Bronzel-JÚnior JL, Silva RMGD, -Peixoto ECTM. PMID: 33084758.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. EMBO J. 2020 11 02; 39(21):e106057. Wang S, Li W, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM. PMID: 32944968.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. AI-guided discovery of the invariant host response to viral pandemics. bioRxiv. 2020 Sep 22. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Crotty Alexander LE, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 32995790.
      View in: PubMed   Mentions:
    10. Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity. Cell. 2020 11 12; 183(4):996-1012.e19. Rydyznski Moderbacher C, Ramirez SI, Dan JM, Grifoni A, Hastie KM, Weiskopf D, Belanger S, Abbott RK, Kim C, Choi J, Kato Y, Crotty EG, Kim C, Rawlings SA, Mateus J, Tse LPV, Frazier A, Baric R, Peters B, Greenbaum J, Ollmann Saphire E, Smith DM, Sette A, Crotty S. PMID: 33010815.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCellsPHPublic Health
    11. No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract. Open Forum Infect Dis. 2020 Aug; 7(8):ofaa325. Rawlings SA, Ignacio C, Porrachia M, Du P, Smith DM, Chaillon A. PMID: 32875005.
      View in: PubMed   Mentions:
    12. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science. 2020 10 02; 370(6512):89-94. Mateus J, Grifoni A, Tarke A, Sidney J, Ramirez SI, Dan JM, Burger ZC, Rawlings SA, Smith DM, Phillips E, Mallal S, Lammers M, Rubiro P, Quiambao L, Sutherland A, Yu ED, da Silva Antunes R, Greenbaum J, Frazier A, Markmann AJ, Premkumar L, de Silva A, Peters B, Crotty S, Sette A, Weiskopf D. PMID: 32753554.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCellsPHPublic Health
    13. Methamphetamine and cardiac disease among people with HIV infection. HIV Med. 2020 Nov; 21(10):635-641. Martin T, Gianella S, Franklin D, Hsue P, Smith DM. PMID: 32741089.
      View in: PubMed   Mentions:    Fields:    
    14. Internet Searches About Infectious Diseases Training During the COVID-19 Pandemic. Open Forum Infect Dis. 2020. Birabaharan M, Smith DM, Wooten D. View Publication.
    15. Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019. J Infect Dis. 2020 06 29; 222(2):206-213. Burbelo PD, Riedo FX, Morishima C, Rawlings S, Smith D, Das S, Strich JR, Chertow DS, Davey RT, Cohen JI. PMID: 32427334.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsPHPublic Health
    16. Perceptions of Next-of-Kin/Loved Ones About Last Gift Rapid Research Autopsy Study Enrolling People with HIV/AIDS at the End of Life: A Qualitative Interview Study. AIDS Res Hum Retroviruses. 2020 12; 36(12):1033-1046. Dubé K, Patel H, Concha-Garcia S, Perry KE, Mathur K, Javadi SS, Taylor J, Kaytes A, Brown B, Sauceda JA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449624.
      View in: PubMed   Mentions: 2     Fields:    
    17. "My Death Will Not [Be] in Vain": Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life. AIDS Res Hum Retroviruses. 2020 Dec; 36(12):1071-1082. Perry KE, Dubé K, Concha-Garcia S, Patel H, Kaytes A, Taylor J, Javadi SS, Mathur K, Lo M, Brown B, Sauceda JA, Wohl DA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449625.
      View in: PubMed   Mentions: 2     Fields:    
    18. Do Sexual Minorities Face Greater Risk for Sexual Harassment, Ever and at School, in Adolescence?: Findings From a 2019 Cross-Sectional Study of U.S. Adults. J Interpers Violence. 2020 Jun 22; 886260520926315. Smith DM, Johns NE, Raj A. PMID: 32571176.
      View in: PubMed   Mentions:    Fields:    
    19. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science. 2020 08 21; 369(6506):956-963. Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. PMID: 32540903.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    20. Performing rapid autopsy for the interrogation of HIV reservoirs. AIDS. 2020 06 01; 34(7):1089-1092. Rawlings SA, Layman L, Smith D, Scott B, Ignacio C, Porrachia M, Concha-Garcia S, Hendrickx S, Kaytes A, Taylor J, Gianella S. PMID: 32287073.
      View in: PubMed   Mentions: 1     Fields:    
    21. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell. 2020 06 25; 181(7):1489-1501.e15. Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR, Rawlings SA, Sutherland A, Premkumar L, Jadi RS, Marrama D, de Silva AM, Frazier A, Carlin AF, Greenbaum JA, Peters B, Krammer F, Smith DM, Crotty S, Sette A. PMID: 32473127.
      View in: PubMed   Mentions: 282     Fields:    Translation:HumansCellsPHPublic Health
    22. Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events. AIDS. 2020 05 01; 34(6):849-857. Gianella S, Moser C, Vitomirov A, McKhann A, Layman L, Scott B, Caballero G, Lada S, Bosch RJ, Hoenigl M, Lurain N, Landay A, Lederman MM, Hunt PW, Smith D. PMID: 32271250.
      View in: PubMed   Mentions: 1     Fields:    
    23. HIV persists throughout deep tissues with repopulation from multiple anatomical sources. J Clin Invest. 2020 04 01; 130(4):1699-1712. Chaillon A, Gianella S, Dellicour S, Rawlings SA, Schlub TE, De Oliveira MF, Ignacio C, Porrachia M, Vrancken B, Smith DM. PMID: 31910162.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    24. Tracing the transmission dynamics of HIV-1 CRF55_01B. Sci Rep. 2020 03 20; 10(1):5098. Zai J, Liu H, Lu Z, Chaillon A, Smith D, Li Y, Li X. PMID: 32198405.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    25. HIV Prevention Method Preferences Within Sexual Partnerships Reported by HIV-Negative MSM and TW in Tijuana, Mexico. AIDS Behav. 2020 Mar; 24(3):839-846. Pines HA, Patrick R, Smith DM, Harvey-Vera A, Blumenthal JS, Rangel G, Semple SJ, Patterson TL. PMID: 30945030.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    26. Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet. Clin Infect Dis. 2020 02 14; 70(5):925-932. Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M. PMID: 30953067.
      View in: PubMed   Mentions: 3     Fields:    
    27. Response to: Is Burnout Infectious? Understanding Drivers of Burnout and Job Satisfaction Among Academic Infectious Diseases Physicians. Open Forum Infect Dis. 2019 Oct; 6(10):ofz378. Wooten D, Smith D. PMID: 31660342.
      View in: PubMed   Mentions:
    28. Pooled nucleic acid testing strategy for monitoring HIV-1 treatment in resource limited settings. J Clin Virol. 2019 08; 117:56-60. J B, Tr D, S G, E E, A P, D C, Kg M, P B, S S, Ss S, N K, Dm S, S S. PMID: 31212189.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    29. Mechanism of Action of Methotrexate Against Zika Virus. Viruses. 2019 04 10; 11(4). Beck S, Zhu Z, Oliveira MF, Smith DM, Rich JN, Bernatchez JA, Siqueira-Neto JL. PMID: 30974762.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    30. Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015. Open Forum Infect Dis. 2019 Apr; 6(4):ofz160. Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK. PMID: 31041355.
      View in: PubMed   Mentions:
    31. HIV-1 drug resistance before initiation or re-initiation of first-line ART in eight regions of Mexico: a sub-nationally representative survey. J Antimicrob Chemother. 2019 04 01; 74(4):1044-1055. Ávila-Ríos S, García-Morales C, Valenzuela-Lara M, Chaillon A, Tapia-Trejo D, Pérez-García M, López-Sánchez DM, Maza-Sánchez L, Del Arenal-Sánchez SJ, Paz-Juárez HE, Quiroz-Morales VS, Mehta SR, Smith DM, León-Juárez EA, Magis-Rodríguez C, Reyes-Terán G. PMID: 30597094.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    32. Herd Immunity Likely Protected the Men Who Have Sex With Men in the Recent Hepatitis A Outbreak in San Diego, California. Clin Infect Dis. 2019 03 19; 68(7):1228-1230. Smith D, Huynh C, Moore AJ, Frick A, Anderson C, Porrachia M, Scott B, Stous S, Schooley R, Little S, Santos AT. PMID: 30052941.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    33. Challenges in Quantifying Cytosine Methylation in the HIV Provirus. mBio. 2019 01 22; 10(1). LaMere SA, Chaillon A, Huynh C, Smith DM, Gianella S. PMID: 30670613.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    34. A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PLoS Negl Trop Dis. 2018 12; 12(12):e0007053. Carlin AF, Wen J, Vizcarra EA, McCauley M, Chaillon A, Akrami K, Kim C, Ngono AE, Lara-Marquez ML, Smith DM, Glass CK, Schooley RT, Benner C, Shresta S. PMID: 30596671.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    35. Baseline Genotype Testing to Assess Drug Resistance Before Beginning HIV Treatment-Reply. JAMA. 2018 11 27; 320(20):2154. Saag MS, Günthard HF, Smith DM. PMID: 30480722.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    36. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    37. Growth of HIV-1 Molecular Transmission Clusters in New York City. J Infect Dis. 2018 11 05; 218(12):1943-1953. Wertheim JO, Murrell B, Mehta SR, Forgione LA, Kosakovsky Pond SL, Smith DM, Torian LV. PMID: 30010850.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    38. Influenza Vaccination Can Broadly Activate the HIV Reservoir During Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2018 11 01; 79(3):e104-e107. Christensen-Quick A, Chaillon A, Yek C, Zanini F, Jordan P, Ignacio C, Caballero G, Gianella S, Smith D. PMID: 30085954.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    39. Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics. 2018 10 20; 19(1):83. Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D. PMID: 30342507.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    40. Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2018 07 24; 320(4):379-396. Saag MS, Benson CA, Gandhi RT, Hoy JF, Landovitz RJ, Mugavero MJ, Sax PE, Smith DM, Thompson MA, Buchbinder SP, Del Rio C, Eron JJ, Fätkenheuer G, Günthard HF, Molina JM, Jacobsen DM, Volberding PA. PMID: 30043070.
      View in: PubMed   Mentions: 115     Fields:    Translation:Humans
    41. Willingness to participate in HIV research at the end of life (EOL). PLoS One. 2018; 13(7):e0199670. Prakash K, Gianella S, Dubé K, Taylor J, Lee G, Smith DM. PMID: 30036365.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy. PLoS Pathog. 2018 05; 14(5):e1007071. Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR, Jones KA. PMID: 29791506.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    43. Erratum to: Factors Associated with Mood Disorder Diagnosis Among a Population Based Cohort of Men and Women Living With and Without HIV in British Columbia Between 1998 and 2012. AIDS Behav. 2018 05; 22(5):1541. Closson K, Osborne C, Smith DM, Kesselring S, Eyawo O, Card K, Sereda P, Jabbari S, Franco-Villalobos C, Ahmed T, Gabler K, Patterson T, Hull M, Montaner JSG, Hogg RS. PMID: 28741132.
      View in: PubMed   Mentions:    Fields:    
    44. Factors Associated with Mood Disorder Diagnosis Among a Population Based Cohort of Men and Women Living With and Without HIV in British Columbia Between 1998 and 2012. AIDS Behav. 2018 05; 22(5):1530-1540. Closson K, Osborne C, Smith DM, Kesselring S, Eyawo O, Card K, Sereda P, Jabbari S, Franco-Villalobos C, Ahmed T, Gabler K, Patterson T, Hull M, Montaner JSG, Hogg RS. PMID: 28612214.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. The Importance of Human Immunodeficiency Virus Research for Transgender and Gender-Nonbinary Individuals. Clin Infect Dis. 2018 04 17; 66(9):1460-1466. Gianella S, Sonya Haw J, Blumenthal J, Sullivan B, Smith D. PMID: 29126186.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    46. Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors. AIDS. 2018 02 20; 32(4):443-450. Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith DM, Little SJ, Lauffenburger DA, Richman DD, Alter G. PMID: 29239894.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    47. Occult HBV infection in HIV-infected adults and evaluation of pooled NAT for HBV. J Viral Hepat. 2018 06; 25(6):718-723. Dinesha TR, Boobalan J, Sivamalar S, Subashini D, Solomon SS, Murugavel KG, Balakrishnan P, Smith DM, Saravanan S. PMID: 29316078.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    48. Impact of Public Safety Policies on Human Immunodeficiency Virus Transmission Dynamics in Tijuana, Mexico. Clin Infect Dis. 2018 02 10; 66(5):758-764. Mehta SR, Chaillon A, Gaines TL, Gonzalez-Zuniga PE, Stockman JK, Almanza-Reyes H, Chavez JR, Vera A, Wagner KD, Patterson TL, Scott B, Smith DM, Strathdee SA. PMID: 29045592.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    49. Mortality among people living with HIV/AIDS with non-small-cell lung cancer in the modern HAART Era. AIDS Care. 2018 07; 30(7):936-942. Smith DM, Salters KA, Eyawo O, Franco-Villalobos C, Jabbari S, Wiseman SM, Press N, Montaner JSG, Man SFP, Hull M, Hogg RS. PMID: 29411625.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol. 2018 02 01; 92(3). Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM. PMID: 29142136.
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    51. HIV, Hepatitis B Virus, and Hepatitis C Virus Prevalence Among High-Risk Populations in South India. AIDS Res Hum Retroviruses. 2018 04; 34(4):327-328. Dinesha TR, Boobalan J, Sivamalar S, Solomon SS, Poongulali S, Pradeep A, Murugavel KG, Balakrishnan P, Smith DM, Saravanan S. PMID: 29161880.
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    52. Suicide Risk Behaviors Among Sexual Minority Adolescents in the United States, 2015. JAMA. 2017 12 19; 318(23):2349-2351. Caputi TL, Smith D, Ayers JW. PMID: 29260214.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. HIV Prevalence and Risk Behaviors in Male to Female (MTF) Transgender Persons in Tijuana, Mexico. AIDS Behav. 2017 Dec; 21(12):3271-3278. Salas-Espinoza KJ, Menchaca-Diaz R, Patterson TL, Urada LA, Smith D, Strathdee SA, Pitpitan EV. PMID: 29032411.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    54. HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity. 2017 11 21; 47(5):990-1003.e9. Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, Wrin T, Algate P, Chan-Hui PY, Karita E, Ward AB, Wilson IA, Burton DR, Smith D, Pond SLK, Poignard P. PMID: 29166592.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    55. No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol. 2017 11 01; 91(21). Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S. PMID: 28794047.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    56. Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection. Antimicrob Agents Chemother. 2017 10; 61(10). Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. PMID: 28807909.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansCells
    57. Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol. 2017 09 01; 91(17). Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. PMID: 28615205.
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    58. Identification of putative unique immunogenic ZIKV and DENV1-4 peptides for diagnostic cellular based tests. Sci Rep. 2017 07 24; 7(1):6218. Oom AL, Smith D, Akrami K. PMID: 28740150.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    59. Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. AIDS. 2017 05 15; 31(8):1149-1158. Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 28244954.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    60. Molecular Features of the V1-V4 Coding Region of Sexually Transmitted Human Immunodeficiency Virus Type 1. J Infect Dis. 2017 05 15; 215(10):1506-1513. Choi JY, Pond SLK, Anderson CM, Richman DD, Smith DM. PMID: 28419276.
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    61. Short Communication: HIV-1 Transmission Networks Across South Korea. AIDS Res Hum Retroviruses. 2017 08; 33(8):827-831. Ahn MY, Wertheim JO, Kim WJ, Kim SW, Lee JS, Ann HW, Jeon Y, Ahn JY, Song JE, Oh DH, Kim YC, Kim EJ, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Smith DM, Choi JY. PMID: 28346838.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    62. Dynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization-case study. J Neurovirol. 2017 06; 23(3):460-473. de Almeida SM, Rotta I, Ribeiro CE, Oliveira MF, Chaillon A, de Pereira AP, Cunha AP, Zonta M, Bents JF, Raboni SM, Smith D, Letendre S, Ellis RJ. PMID: 28247269.
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    63. Lyophilized visually readable loop-mediated isothermal reverse transcriptase nucleic acid amplification test for detection Ebola Zaire RNA. J Virol Methods. 2017 06; 244:32-38. Carter C, Akrami K, Hall D, Smith D, Aronoff-Spencer E. PMID: 28242293.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    64. Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies. Retrovirology. 2017 Feb 21; 14(1):15. Chaillon A, Essat A, Frange P, Smith DM, Delaugerre C, Barin F, Ghosn J, Pialoux G, Robineau O, Rouzioux C, Goujard C, Meyer L, Chaix ML. PMID: 28222757.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    65. Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis. 2017 02 15; 64(4):428-434. Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S. PMID: 28174909.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    66. Now is the Time to Study the Timing of Influenza Vaccine. HIV Med. 2018 03; 19(3):e53. Glinka ER, Smith DM, Johns ST. PMID: 28116796.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    67. Partner services in adults with acute and early HIV infection. AIDS. 2017 01 14; 31(2):287-293. Green N, Hoenigl M, Chaillon A, Anderson CM, Kosakovsky Pond SL, Smith DM, Little SJ. PMID: 27831950.
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    68. Social and Genetic Networks of HIV-1 Transmission in New York City. PLoS Pathog. 2017 01; 13(1):e1006000. Wertheim JO, Kosakovsky Pond SL, Forgione LA, Mehta SR, Murrell B, Shah S, Smith DM, Scheffler K, Torian LV. PMID: 28068413.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCellsPHPublic Health
    69. Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 01; 13(1):e1006112. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. PMID: 28046096.
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    70. Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 01 02; 31(1):1-4. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. PMID: 27755112.
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    71. HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection. . 2017 01 01; 74(1):95-102. Chaillon A, Smith DM, Vanpouille C, Lisco A, Jordan P, Caballero G, Vargas M, Gianella S, Mehta SR. PMID: 27548440.
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    72. Etravirine and Rilpivirine Drug Resistance Among HIV-1 Subtype C Infected Children Failing Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimens in South India. AIDS Res Hum Retroviruses. 2017 06; 33(6):567-574. Saravanan S, Kausalya B, Gomathi S, Sivamalar S, Pachamuthu B, Selvamuthu P, Pradeep A, Sunil S, Mothi SN, Smith DM, Kantor R. PMID: 27869478.
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    73. Identification of Two New HIV-1 Circulating Recombinant Forms (CRF87_cpx and CRF88_BC) from Reported Unique Recombinant Forms in Asia. AIDS Res Hum Retroviruses. 2017 04; 33(4):353-358. Hu Y, Wan Z, Zhou YH, Smith D, Zheng YT, Zhang C. PMID: 27762598.
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    74. HIV-associated neurocognitive disorder is associated with HIV-1 dual infection. AIDS. 2016 11 13; 30(17):2591-2597. Wagner GA, Chaillon A, Liu S, Franklin DR, Caballero G, Kosakovsky Pond SL, Vaida F, Heaton RK, Letendre SL, Grant I, Richman DD, Smith DM. PMID: 27536983.
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    75. Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection. J Neuroimmunol. 2016 12 15; 301:41-48. de Almeida SM, Rotta I, Ribeiro CE, Smith D, Wang R, Judicello J, Potter M, Vaida F, Letendre S, Ellis RJ. PMID: 27836178.
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    76. A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine (Baltimore). 2016 Nov; 95(44):e5315. Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. PMID: 27858912.
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    77. Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults. Clin Infect Dis. 2016 Dec 15; 63(12):1655-1660. Bharti AR, McCutchan A, Deutsch R, Smith DM, Ellis RJ, Cherner M, Woods SP, Heaton RK, Grant I, Letendre SL. PMID: 27794019.
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    78. (1?3)-ß-d-Glucan: A Biomarker for Microbial Translocation in Individuals with Acute or Early HIV Infection? Front Immunol. 2016; 7:404. Hoenigl M, Pérez-Santiago J, Nakazawa M, de Oliveira MF, Zhang Y, Finkelman MA, Letendre S, Smith D, Gianella S. PMID: 27752257.
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    79. Standard vaccines increase HIV-1 transcription during antiretroviral therapy. AIDS. 2016 09 24; 30(15):2289-98. Yek C, Gianella S, Plana M, Castro P, Scheffler K, García F, Massanella M, Smith DM. PMID: 27427877.
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    80. Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment. Clin Infect Dis. 2016 Dec 01; 63(11):1517-1524. Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S. PMID: 27601222.
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    81. First description of two new HIV-1 recombinant forms CRF82_cpx and CRF83_cpx among drug users in Northern Myanmar. Virulence. 2017 07 04; 8(5):497-503. Chen X, Ye M, Duo L, Pang W, Smith D, Zhang C, Zheng YT. PMID: 27574950.
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    82. First Appearance of HIV-1 CRF07_BC and CRF08_BC Outside China. AIDS Res Hum Retroviruses. 2017 01; 33(1):74-76. Chen X, Ye M, Pang W, Smith DM, Zhang C, Zheng YT. PMID: 27392826.
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    83. Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions. J Infect. 2016 11; 73(5):476-484. Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ. PMID: 27521468.
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    84. Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy. Virus Evol. 2016 Jul; 2(2):vew020. Gianella S, Kosakovsky Pond SL, Oliveira MF, Scheffler K, Strain MC, De la Torre A, Letendre S, Smith DM, Ellis RJ. PMID: 27774305.
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    85. Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2016 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2016 Jul 12; 316(2):191-210. Günthard HF, Saag MS, Benson CA, del Rio C, Eron JJ, Gallant JE, Hoy JF, Mugavero MJ, Sax PE, Thompson MA, Gandhi RT, Landovitz RJ, Smith DM, Jacobsen DM, Volberding PA. PMID: 27404187.
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    86. Biomarkers of chemotaxis and inflammation in cerebrospinal fluid and serum in individuals with HIV-1 subtype C versus B. J Neurovirol. 2016 12; 22(6):715-724. de Almeida SM, Rotta I, Jiang Y, Li X, Raboni SM, Ribeiro CE, Smith D, Potter M, Vaida F, Letendre S, Ellis RJ. PMID: 27400932.
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    87. Rapid Sequencing of Complete env Genes from Primary HIV-1 Samples. Virus Evol. 2016 Jul; 2(2):vew018. Laird Smith M, Murrell B, Eren K, Ignacio C, Landais E, Weaver S, Phung P, Ludka C, Hepler L, Caballero G, Pollner T, Guo Y, Richman D, Poignard P, Paxinos EE, Kosakovsky Pond SL, Smith DM. PMID: 29492273.
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    88. The dynamics of the HIV epidemic among men who have sex with men (MSM) from 2005 to 2012 in Shenzhen, China. Sci Rep. 2016 06 29; 6:28703. Zhao J, Chen L, Chaillon A, Zheng C, Cai W, Yang Z, Li G, Gan Y, Wang X, Hu Y, Zhong P, Zhang C, Smith DM. PMID: 27352965.
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    89. A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics. Sci Rep. 2016 06 24; 6:28707. Chaillon A, Hoenigl M, Mehta SR, Weibel N, Little SJ, Smith DM. PMID: 27337983.
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    90. Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART. . 2016 06 01; 72(2):133-7. Dan JM, Massanella M, Smith DM, Spina CA, Schrier R, Daar ES, Dube MP, Morris SR, Gianella S. PMID: 26818740.
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    91. The Veterans Aging Cohort Study (VACS) Index and Neurocognitive Change: A Longitudinal Study. Clin Infect Dis. 2016 Sep 01; 63(5):694-702. Marquine MJ, Montoya JL, Umlauf A, Fazeli PL, Gouaux B, Heaton RK, Ellis RJ, Letendre SL, Grant I, Moore DJ. PMID: 27199461.
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    92. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clin Infect Dis. 2016 07 01; 63(1):101-107. Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. PMID: 27174704.
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    93. Characteristics of Resting-State Functional Connectivity in HIV-Associated Neurocognitive Disorder. PLoS One. 2016; 11(4):e0153493. Ann HW, Jun S, Shin NY, Han S, Ahn JY, Ahn MY, Jeon YD, Jung IY, Kim MH, Jeong WY, Ku NS, Kim JM, Smith DM, Choi JY. PMID: 27104345.
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    94. Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men. . 2016 Apr 15; 71(5):551-7. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Smith DM, Little SJ. PMID: 26536321.
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    95. Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection. J Virol. 2016 Apr; 90(8):3944-3952. Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM. PMID: 26842469.
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    96. Molecular epidemiology identifies HIV transmission networks associated with younger age and heterosexual exposure among Korean individuals. J Med Virol. 2016 10; 88(10):1832-5. Chin BS, Chaillon A, Mehta SR, Wertheim JO, Kim G, Shin HS, Smith DM. PMID: 26990771.
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    97. Mitochondrial injury and cognitive function in HIV infection and methamphetamine use. AIDS. 2016 Mar 27; 30(6):839-48. Var SR, Day TR, Vitomirov A, Smith DM, Soontornniyomkij V, Moore DJ, Achim CL, Mehta SR, Pérez-Santiago J. PMID: 26807965.
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    98. Shedding of Hepatitis C Virus in Semen of Human Immunodeficiency Virus-Infected Men. Open Forum Infect Dis. 2016 Mar; 3(2):ofw057. Turner SS, Gianella S, Yip MJ, van Seggelen WO, Gillies RD, Foster AL, Barbati ZR, Smith DM, Fierer DS. PMID: 27186582.
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    99. Neurobehavioral Disturbances During Acute and Early HIV Infection. Cogn Behav Neurol. 2016 Mar; 29(1):1-10. Kamat R, Doyle KL, Iudicello JE, Morgan EE, Morris S, Smith DM, Little SJ, Grant I, Woods SP. PMID: 27008244.
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    100. Validation of the GeneXpert® CT/NG Assay for use with Male Pharyngeal and Rectal Swabs. Austin J HIV AIDS Res. 2016; 3(1). Geiger R, Smith DM, Little SJ, Mehta SR. PMID: 27536736.
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    101. Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening. Emerg Infect Dis. 2016 Mar; 22(3):532-4. Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ. PMID: 26890854.
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    102. Prevalence of Transmitted HIV Drug Resistance Among Recently Infected Persons in San Diego, CA 1996-2013. . 2016 Feb 01; 71(2):228-36. Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. PMID: 26413846.
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    103. Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series. Open Forum Infect Dis. 2016 Jan; 3(1):ofw014. Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM. PMID: 26925432.
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    104. Timing Matters - Influenza Vaccination to HIV-Infected Patients. HIV Med. 2016 09; 17(8):601-4. Glinka ER, Smith DM, Johns ST. PMID: 26810556.
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    105. Corrigendum: Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2016 Jan 19; 6:19387. de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. PMID: 26783252.
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    106. Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection. AIDS. 2016 Jan; 30(2):193-201. Vanpouille C, Introini A, Morris SR, Margolis L, Daar ES, Dube MP, Little SJ, Smith DM, Lisco A, Gianella S. PMID: 26558730.
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    107. RETRACTED: Investigation of the GeneXpert® CT/NG assay for use with male pharyngeal and rectal swabs. Int J STD AIDS. 2016 Jan 01; 956462416665059. Geiger R, Smith DM, Little SJ, Mehta SR. PMID: 27510643.
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    108. A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines. Cancer Lett. 2016 Feb 28; 371(2):285-91. Shi Y, Wang J, Wang Y, Wang A, Guo H, Wei F, Mehta SR, Espitia S, Smith DM, Liu L, Zhang Y, Chen D. PMID: 26706415.
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    109. Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2015 Nov 25; 5:17094. de Oliveira MF, Murrell B, Murrel B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. PMID: 26603568.
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    110. Pooled Nucleic Acid Testing to Detect Antiretroviral Treatment Failure in HIV-Infected Patients in Mozambique. . 2015 Nov 01; 70(3):256-61. Tilghman M, Tsai D, Buene TP, Tomas M, Amade S, Gehlbach D, Chang S, Ignacio C, Caballero G, Espitia S, May S, Noormahomed EV, Smith DM. PMID: 26135327.
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    111. No evidence of posttreatment control after early initiation of antiretroviral therapy. AIDS. 2015 Oct 23; 29(16):2093-7. Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 26544575.
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    112. Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR. PLoS One. 2015; 10(10):e0139510. de Oliveira MF, Gianella S, Letendre S, Scheffler K, Kosakovsky Pond SL, Smith DM, Strain M, Ellis RJ. PMID: 26431315.
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    113. Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection. J Neurovirol. 2016 Apr; 22(2):191-200. Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TR, Ramirez-Gaona M, Suben JD, Murrell B, Massanella M, Cherner M, Smith DM, Ellis RJ, Letendre SL, Mehta SR. PMID: 26428514.
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    114. HIV migration between blood plasma and cellular subsets before and after HIV therapy. J Med Virol. 2016 Apr; 88(4):606-13. Choi JY, Chaillon A, Oh JO, Ahn JY, Ann HW, Jung IY, Ahn MY, Jeon YD, Ku NS, Smith DM, Kim JM. PMID: 26348372.
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    115. Repeat HIV-testing is associated with an increase in behavioral risk among men who have sex with men: a cohort study. BMC Med. 2015 Sep 11; 13:218. Hoenigl M, Anderson CM, Green N, Mehta SR, Smith DM, Little SJ. PMID: 26444673.
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    116. Subtype associations with HIV-associated neurocognitive disorder in China. J Neurovirol. 2016 Apr; 22(2):246-50. Day TR, Smith DM, Heaton RK, Franklin D, Tilghman MW, Letendre S, Jin H, Wu Z, Shi C, Yu X, Pérez-Santiago J. PMID: 26306690.
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    117. Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Sci Rep. 2015 Aug 24; 5:13179. Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. PMID: 26299251.
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    118. What Can We Learn From Measles? No New HIV Infections. Top Antivir Med. 2015 Aug-Sep; 23(3):108-10. Smith DM. PMID: 26518393.
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    119. The need for treatment interruption studies and biomarker identification in the search for an HIV cure. AIDS. 2015 Jul 31; 29(12):1429-32. Li JZ, Smith DM, Mellors JW. PMID: 25870989.
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    120. HIV Transmission Networks in the San Diego-Tijuana Border Region. EBioMedicine. 2015 Oct; 2(10):1456-63. Mehta SR, Wertheim JO, Brouwer KC, Wagner KD, Chaillon A, Strathdee S, Patterson TL, Rangel MG, Vargas M, Murrell B, Garfein R, Little SJ, Smith DM. PMID: 26629540.
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    121. Seminal Shedding of CMV and HIV Transmission among Men Who Have Sex with Men. Int J Environ Res Public Health. 2015 Jul 07; 12(7):7585-92. Gianella S, Scheffler K, Mehta SR, Little SJ, Freitas L, Morris SR, Smith DM. PMID: 26198239.
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    122. Targeting HIV Prevention Based on Molecular Epidemiology Among Deeply Sampled Subnetworks of Men Who Have Sex With Men. Clin Infect Dis. 2015 Nov 01; 61(9):1462-8. Wang X, Wu Y, Mao L, Xia W, Zhang W, Dai L, Mehta SR, Wertheim JO, Dong X, Zhang T, Wu H, Smith DM. PMID: 26129754.
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    123. Genital Cytomegalovirus Replication Predicts Syphilis Acquisition among HIV-1 Infected Men Who Have Sex with Men. PLoS One. 2015; 10(6):e0130410. Gianella S, Smith DM, Daar ES, Dube MP, Lisco A, Vanpouille C, Margolis L, Haubrich RH, Morris SR. PMID: 26061824.
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    124. Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis. PLoS Med. 2015 Jun; 12(6):e1001845. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Kee PN, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. PMID: 26030872.
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    125. Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection. Mucosal Immunol. 2016 Jan; 9(1):24-37. Dillon SM, Lee EJ, Kotter CV, Austin GL, Gianella S, Siewe B, Smith DM, Landay AL, McManus MC, Robertson CE, Frank DN, McCarter MD, Wilson CC. PMID: 25921339.
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    126. Differences in Evolution of HIV-1 Subtype C Reverse Transcriptase Between Children and Adults Likely Explained by Maturity of Cytotoxic T-Lymphocyte Responses. AIDS Res Hum Retroviruses. 2015 Jun; 31(6):655-7. Saravanan S, Gomathi S, Kausalya B, Boobalan J, Murugavel KG, Balakrishnan P, Mothi SN, Solomon SS, Kumarasamy N, Selvamuthu P, Solomon S, Smith DM. PMID: 25839730.
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    127. Short Communication: Increase of HIV-1 K103N Transmitted Drug Resistance and Its Association with Efavirenz Use in South Korea. AIDS Res Hum Retroviruses. 2015 Jun; 31(6):603-7. Chin BS, Shin HS, Kim G, Wagner GA, Gianella S, Smith DM. PMID: 25826122.
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    128. Development and validation of the San Diego Early Test Score to predict acute and early HIV infection risk in men who have sex with men. Clin Infect Dis. 2015 Aug 01; 61(3):468-75. Hoenigl M, Weibel N, Mehta SR, Anderson CM, Jenks J, Green N, Gianella S, Smith DM, Little SJ. PMID: 25904374.
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    129. Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis. PLoS Med. 2015 Apr; 12(4):e1001810. Rhee SY, Blanco JL, Jordan MR, Taylor J, Lemey P, Varghese V, Hamers RL, Bertagnolio S, Rinke de Wit TF, Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bessong PO, Brooks JI, Boucher CA, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Li Y, Lutsar I, Morris L, Ndembi N, Ng KP, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rolland M, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Tee KK, Truong HM, van de Vijver DA, Vidal N, Yang C, Yang R, Yebra G, Ioannidis JP, Vandamme AM, Shafer RW. PMID: 25849352.
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    130. The Sordid Affair Between Human Herpesvirus and HIV. J Infect Dis. 2015 Sep 15; 212(6):845-52. Gianella S, Massanella M, Wertheim JO, Smith DM. PMID: 25748324.
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    131. Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection. Mol Biol Evol. 2015 May; 32(5):1342-53. Smith MD, Wertheim JO, Weaver S, Murrell B, Scheffler K, Kosakovsky Pond SL. PMID: 25697341.
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    133. Reply to Haddow et al. Clin Infect Dis. 2015 May 01; 60(9):1442-3. Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I. PMID: 25645217.
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    134. Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals. JAMA Intern Med. 2015 Jan; 175(1):88-99. Okulicz JF, Le TD, Agan BK, Camargo JF, Landrum ML, Wright E, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. PMID: 25419650.
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    135. Hepatitis B virus compartmentalization in the cerebrospinal fluid of HIV-infected patients. Clin Microbiol Infect. 2015 Apr; 21(4):387.e5-8. Ene L, Duiculescu D, Tardei G, Ruta S, Smith DM, Mehta S, Letendre S, Achim CL. PMID: 25658525.
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    136. Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure. J Clin Virol. 2015 Jan; 62:48-53. Fisher RG, Smith DM, Murrell B, Slabbert R, Kirby BM, Edson C, Cotton MF, Haubrich RH, Kosakovsky Pond SL, Van Zyl GU. PMID: 25542470.
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    137. HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing. Virology. 2015 Jan 01; 474:34-40. Carter CC, Wagner GA, Hightower GK, Caballero G, Phung P, Richman DD, Pond SL, Smith DM. PMID: 25463602.
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    138. Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study. Clin Infect Dis. 2015 Feb 01; 60(3):473-80. Heaton RK, Franklin DR, Deutsch R, Letendre S, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst AC, Fennema-Notestine C, Smith DM, Grant I. PMID: 25362201.
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    139. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. PLoS Comput Biol. 2014 Sep; 10(9):e1003842. Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. PMID: 25254639.
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    140. Pre-exposure prophylaxis accessibility research and evaluation (PrEPARE Study). AIDS Behav. 2014 Sep; 18(9):1722-5. King HL, Keller SB, Giancola MA, Rodriguez DA, Chau JJ, Young JA, Little SJ, Smith DM. PMID: 25017425.
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    141. Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence. PLoS One. 2014; 9(7):e102555. Desplats P, Dumaop W, Cronin P, Gianella S, Woods S, Letendre S, Smith D, Masliah E, Grant I. PMID: 25054922.
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    142. Cerebrospinal fluid can be used for HIV genotyping when it fails in blood. Arq Neuropsiquiatr. 2014 Jul; 72(7):506-9. Rotta I, Raboni SM, Ribeiro CE, Riedel M, Winhescki Mda G, Smith DM, Ellis RJ, de Almeida SM. PMID: 25054982.
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    143. Evolutionary origins of human herpes simplex viruses 1 and 2. Mol Biol Evol. 2014 Sep; 31(9):2356-64. Wertheim JO, Smith MD, Smith DM, Scheffler K, Kosakovsky Pond SL. PMID: 24916030.
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    144. Using HIV networks to inform real time prevention interventions. PLoS One. 2014; 9(6):e98443. Little SJ, Kosakovsky Pond SL, Anderson CM, Young JA, Wertheim JO, Mehta SR, May S, Smith DM. PMID: 24901437.
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    145. Antigen-presenting phagocytic cells ingest malaria parasites and increase HIV replication in a tumor necrosis factor a-dependent manner. J Infect Dis. 2014 Nov 15; 210(10):1562-72. Orlov M, Vaida F, Williamson K, Deng Q, Smith DM, Duffy PE, Schooley RT. PMID: 24903666.
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    146. Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients. AIDS Res Hum Retroviruses. 2014 Aug; 30(8):827-9. Jeong SJ, Kim MH, Song JE, Ahn JY, Kim SB, Ann HW, Kim JK, Choi H, Ku NS, Han SH, Kim JM, Smith DM, Kim HS, Choi JY. PMID: 24724838.
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    147. Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology. 2014 Jun 10; 82(23):2055-62. Grant I, Franklin DR, Deutsch R, Woods SP, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Heaton RK. PMID: 24814848.
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    148. Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. J Virol. 2014 Jul; 88(14):7818-27. Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM. PMID: 24789781.
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    149. Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection. AIDS. 2014 Mar 27; 28(6):841-9. Karris MY, Kao YT, Patel D, Dawson M, Woods SP, Vaida F, Spina C, Richman D, Little S, Smith DM. PMID: 24401640.
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    150. Mathematical modeling of HIV prevention measures including pre-exposure prophylaxis on HIV incidence in South Korea. PLoS One. 2014; 9(3):e90080. Kim SB, Yoon M, Ku NS, Kim MH, Song JE, Ahn JY, Jeong SJ, Kim C, Kwon HD, Lee J, Smith DM, Choi JY. PMID: 24662776.
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    151. HIV-associated neurocognitive disorder in HIV-infected Koreans: the Korean NeuroAIDS Project. HIV Med. 2014 Sep; 15(8):470-7. Ku NS, Lee Y, Ahn JY, Song JE, Kim MH, Kim SB, Jeong SJ, Hong KW, Kim E, Han SH, Song JY, Cheong HJ, Song YG, Kim WJ, Kim JM, Smith DM, Choi JY. PMID: 24580888.
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    152. Community HIV-1 drug resistance is associated with transmitted drug resistance. HIV Med. 2014 Jul; 15(6):339-46. Tilghman MW, Pérez-Santiago J, Osorio G, Little SJ, Richman DD, Mathews WC, Haubrich RH, Smith DM. PMID: 24417811.
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    153. An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. Mucosal Immunol. 2014 Jul; 7(4):983-94. Dillon SM, Lee EJ, Kotter CV, Austin GL, Dong Z, Hecht DK, Gianella S, Siewe B, Smith DM, Landay AL, Robertson CE, Frank DN, Wilson CC. PMID: 24399150.
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    154. Strengthening research capacity through the medical education partnership initiative: the Mozambique experience. Hum Resour Health. 2013 Dec 05; 11:62. Noormahomed EV, Mocumbi AO, Preziosi M, Damasceno A, Bickler S, Smith DM, Funzamo C, Aronoff-Spencer E, Badaró R, Mabila F, Bila D, Nguenha A, Do Rosário V, Benson CA, Schooley RT, Patel S, Ferrão LJ, Carrilho C. PMID: 24304706.
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    155. HIV migration between blood and cerebrospinal fluid or semen over time. J Infect Dis. 2014 May 15; 209(10):1642-52. Chaillon A, Gianella S, Wertheim JO, Richman DD, Mehta SR, Smith DM. PMID: 24302756.
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    156. Neurocognitive impairment in HIV-1 clade C- versus B-infected individuals in Southern Brazil. J Neurovirol. 2013 Dec; 19(6):550-6. de Almeida SM, Ribeiro CE, de Pereira AP, Badiee J, Cherner M, Smith D, Maich I, Raboni SM, Rotta I, Barbosa FJ, Heaton RK, Umlauf A, Ellis RJ. PMID: 24277437.
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    157. Real-world impact of neurocognitive deficits in acute and early HIV infection. J Neurovirol. 2013 Dec; 19(6):565-73. Doyle KL, Morgan EE, Morris S, Smith DM, Little S, Iudicello JE, Blackstone K, Moore DJ, Grant I, Letendre SL, Woods SP. PMID: 24277439.
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    158. Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States. J Infect Dis. 2014 Apr 01; 209(7):1032-8. Wagner GA, Pacold ME, Kosakovsky Pond SL, Caballero G, Chaillon A, Rudolph AE, Morris SR, Little SJ, Richman DD, Smith DM. PMID: 24273040.
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    159. Pooled nucleic acid testing to identify antiretroviral treatment failure during HIV infection in Seoul, South Korea. Scand J Infect Dis. 2014 Feb; 46(2):136-40. Kim SB, Kim HW, Kim HS, Ann HW, Kim JK, Choi H, Kim MH, Song JE, Ahn JY, Ku NS, Oh DH, Kim YC, Jeong SJ, Han SH, Kim JM, Smith DM, Choi JY. PMID: 24228824.
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    160. Antibody response to Achromobacter xylosoxidans during HIV infection is associated with lower CD4 levels and increased lymphocyte activation. Clin Vaccine Immunol. 2014 Jan; 21(1):46-50. Tatro ET, Purnajo I, Richman DD, Smith DM, Gianella S. PMID: 24173027.
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    162. Genetic attributes of blood-derived subtype-C HIV-1 tat and env in India and neurocognitive function. J Med Virol. 2014 Jan; 86(1):88-96. Tilghman MW, Bhattacharya J, Deshpande S, Ghate M, Espitia S, Grant I, Marcotte TD, Smith D, Mehendale S. PMID: 24150902.
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    163. Novel codon insert in HIV type 1 clade B reverse transcriptase associated with low-level viremia during antiretroviral therapy. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):165-9. Chaillon A, Gianella S, Vazquez H, Ignacio C, Zweig AC, Richman DD, Smith DM. PMID: 24020934.
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    164. Dual-mixed HIV-1 coreceptor tropism and HIV-associated neurocognitive deficits. J Neurovirol. 2013 Oct; 19(5):488-94. Morris SR, Woods SP, Deutsch R, Little SJ, Wagner G, Morgan EE, Heaton RK, Letendre SL, Grant I, Smith DM. PMID: 24078557.
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    166. Virologic correlates of anti-CMV IgG levels in HIV-1-infected men. J Infect Dis. 2014 Feb 01; 209(3):452-6. Gianella S, Morris SR, Tatro E, Vargas MV, Haubrich RH, Daar ES, Dube MP, Richman DD, Little SJ, Smith DM. PMID: 23964106.
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    167. Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. AIDS. 2013 Jul 31; 27(12):1921-31. Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM. PMID: 24180001.
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    168. HIV-1 clade B pol evolution following primary infection. PLoS One. 2013; 8(6):e68188. Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL. PMID: 23840830.
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    169. Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine. J Infect Dis. 2013 Jun 15; 207 Suppl 2:S70-7. Tang MW, Rhee SY, Bertagnolio S, Ford N, Holmes S, Sigaloff KC, Hamers RL, de Wit TF, Fleury HJ, Kanki PJ, Ruxrungtham K, Hawkins CA, Wallis CL, Stevens W, van Zyl GU, Manosuthi W, Hosseinipour MC, Ngo-Giang-Huong N, Belec L, Peeters M, Aghokeng A, Bunupuradah T, Burda S, Cane P, Cappelli G, Charpentier C, Dagnra AY, Deshpande AK, El-Katib Z, Eshleman SH, Fokam J, Gody JC, Katzenstein D, Koyalta DD, Kumwenda JJ, Lallemant M, Lynen L, Marconi VC, Margot NA, Moussa S, Ndung'u T, Nyambi PN, Orrell C, Schapiro JM, Schuurman R, Sirivichayakul S, Smith D, Zolfo M, Jordan MR, Shafer RW. PMID: 23687292.
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    170. High prevalence of hepatitis delta virus among patients with chronic hepatitis B virus infection and HIV-1 in an intermediate hepatitis B virus endemic region. J Int Assoc Provid AIDS Care. 2014 Jan-Feb; 13(1):85-90. Saravanan S, Madhavan V, Velu V, Murugavel KG, Waldrop G, Solomon SS, Balakrishnan P, Kumarasamy N, Smith DM, Mayer KH, Solomon S, Thyagarajan SP. PMID: 23722085.
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    171. Reply to Mounzer and DiNubile. J Infect Dis. 2013 Aug 15; 208(4):711-2. Morris SR, Smith DM, Little SJ, Gianella S. PMID: 23667136.
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    172. Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection. J Infect Dis. 2013 Jul 15; 208(2):271-4. Wagner GA, Pacold ME, Vigil E, Caballero G, Morris SR, Kosakovsky Pond SL, Little SJ, Richman DD, Gianella S, Smith DM. PMID: 23599311.
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    177. Cytokines in CSF correlate with HIV-associated neurocognitive disorders in the post-HAART era in China. J Neurovirol. 2013 Apr; 19(2):144-9. Yuan L, Qiao L, Wei F, Yin J, Liu L, Ji Y, Smith D, Li N, Chen D. PMID: 23389619.
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    178. Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. N Engl J Med. 2013 Jan 17; 368(3):218-30. Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. PMID: 23323898.
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    179. Phylogenetic relatedness of HIV-1 donor and recipient populations. J Infect Dis. 2013 Apr; 207(7):1181-2. Wertheim JO, Scheffler K, Choi JY, Smith DM, Kosakovsky Pond SL. PMID: 23315327.
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    180. Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract. AIDS. 2013 Jan 02; 27(1):39-47. Gianella S, Morris SR, Anderson C, Spina CA, Vargas MV, Young JA, Richman DD, Little SJ, Smith DM. PMID: 22739399.
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    181. Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. J Infect Dis. 2013 Mar 15; 207(6):898-902. Gianella S, Anderson CM, Vargas MV, Richman DD, Little SJ, Morris SR, Smith DM. PMID: 23275608.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    182. Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection. Clin Infect Dis. 2013 Apr; 56(7):1038-43. Fierer DS, Dieterich DT, Fiel MI, Branch AD, Marks KM, Fusco DN, Hsu R, Smith DM, Fierer J. PMID: 23264364.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    183. Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection. J Neurovirol. 2013 Feb; 19(1):65-74. Weber E, Morgan EE, Iudicello JE, Blackstone K, Grant I, Ellis RJ, Letendre SL, Little S, Morris S, Smith DM, Moore DJ, Woods SP. PMID: 23250704.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    184. Darunavir is a good third-line antiretroviral agent for HIV type 1-infected patients failing second-line protease inhibitor-based regimens in South India. AIDS Res Hum Retroviruses. 2013 Mar; 29(3):630-2. Saravanan S, Madhavan V, Balakrishnan P, Smith DM, Solomon SS, Sivamalar S, Poongulali S, Kumarasamy N, Schooley RT, Solomon S, Kantor R. PMID: 23045961.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    185. Role of seminal shedding of herpesviruses in HIV Type 1 Transmission. J Infect Dis. 2013 Jan 15; 207(2):257-61. Gianella S, Morris SR, Vargas MV, Young JA, Callahan B, Richman DD, Little SJ, Smith DM. PMID: 23148284.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    186. P. falciparum enhances HIV replication in an experimental malaria challenge system. PLoS One. 2012; 7(6):e39000. Orlov M, Vaida F, Finney OC, Smith DM, Talley AK, Wang R, Kappe SH, Deng Q, Schooley RT, Duffy PE. PMID: 22745697.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    187. Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry. EMBO J. 2011 Jul 08; 30(15):3065-77. Deriziotis P, André R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH, Collinge J, Goldberg AL, Tabrizi SJ. PMID: 21743439.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    188. ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell. 2011 Feb 18; 144(4):526-38. Smith DM, Fraga H, Reis C, Kafri G, Goldberg AL. PMID: 21335235.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    189. Differences in tuberculin reactivity as determined in a veterans administration employee health screening program. Clin Vaccine Immunol. 2009 Apr; 16(4):541-3. Mehta SR, MacGruder C, Looney D, Johns S, Smith DM. PMID: 19225075.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    190. A public health model for the molecular surveillance of HIV transmission in San Diego, California. AIDS. 2009 Jan 14; 23(2):225-32. Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. PMID: 19098493.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCellsPHPublic Health
    191. Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 2009 Mar 01; 385(1):204-8. Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ. PMID: 19100592.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    192. Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men. AIDS. 2008 Aug 20; 22(13):1667-71. Butler DM, Smith DM, Cachay ER, Hightower GK, Nugent CT, Richman DD, Little SJ. PMID: 18670228.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCellsPHPublic Health
    193. Running with scissors: using antiretroviral therapy without monitoring viral load. Clin Infect Dis. 2008 May 15; 46(10):1598-600. Smith DM, Schooley RT. PMID: 18419496.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    194. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. AIDS. 2008 Apr 23; 22(7):835-9. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. PMID: 18427201.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    195. Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. J Virol. 2008 Jun; 82(11):5510-8. Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. PMID: 18353964.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    196. Active duty military personnel presenting for care at a Gay Men's Health Clinic. J Homosex. 2008; 54(3):277-9. Smith DM. PMID: 18825864.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    197. Active methamphetamine use is associated with transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors in individuals with HIV infection of unknown duration. Open AIDS J. 2007; 1:5-10. Cachay ER, Moini N, Kosakovsky Pond SL, Pesano R, Lie YS, Aiem H, Butler DM, Letendre S, Mathews WC, Smith DM. PMID: 18923691.
      View in: PubMed   Mentions:
    198. Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis. 2007 Aug 01; 196(3):356-60. Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. PMID: 17597449.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    199. Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. J Infect Dis. 2007 May 01; 195(9):1270-7. Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. PMID: 17396995.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    200. Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1. J Virol. 2007 May; 81(9):4776-86. Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC. PMID: 17329339.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    201. Physicians' attitudes toward homosexuality and HIV: survey of a California Medical Society- revisited (PATHH-II). J Homosex. 2007; 52(3-4):1-9. Smith DM, Mathews WC. PMID: 17594969.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    202. Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection. Clin Infect Dis. 2007 Feb 01; 44(3):456-8. Smith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, Richman D, Little S. PMID: 17205459.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    203. Characteristics of recently HIV-infected men who use the Internet to find male sex partners and sexual practices with those partners. . 2006 Dec 15; 43(5):582-7. Smith DM, Drumright LN, Frost SD, Cheng WS, Espitia S, Daar ES, Little SJ, Gorbach PM. PMID: 17019370.
      View in: PubMed   Mentions:
    204. Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 2006 Nov 10; 355(1):1-5. Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. PMID: 16962152.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    205. Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain. 2006 Jul; 129(Pt 7):1872-83. Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. PMID: 16735456.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    206. Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J Infect Dis. 2006 Jul 01; 194(1):29-37. Goicoechea M, Smith DM, Liu L, May S, Tenorio AR, Ignacio CC, Landay A, Haubrich R. PMID: 16741879.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    207. The controversies of nevirapine for preventing mother-to-child HIV transmission. AIDS. 2006 Jan 09; 20(2):281-3. Smith DM. PMID: 16511423.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    208. Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18514-9. Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. PMID: 16339909.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansCells
    209. HIV drug resistance acquired through superinfection. AIDS. 2005 Aug 12; 19(12):1251-6. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. PMID: 16052079.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    210. Naturally occurring proteasome inhibitors from mate tea (Ilex paraguayensis) serve as models for topical proteasome inhibitors. J Invest Dermatol. 2005 Aug; 125(2):207-12. Arbiser JL, Li XC, Hossain CF, Nagle DG, Smith DM, Miller P, Govindarajan B, DiCarlo J, Landis-Piwowar KR, Dou QP. PMID: 16098028.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    211. HIV treatment decisions and transmitted drug resistance. Clin Infect Dis. 2005 Jul 15; 41(2):233-5. Little SJ, Smith DM. PMID: 15983921.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    212. Semen-specific genetic characteristics of human immunodeficiency virus type 1 env. J Virol. 2005 Feb; 79(3):1734-42. Pillai SK, Good B, Pond SK, Wong JK, Strain MC, Richman DD, Smith DM. PMID: 15650198.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    213. Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol. 2005 Feb; 79(3):1772-88. Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. PMID: 15650202.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    214. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. J Virol. 2005 Jan; 79(2):860-8. Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. PMID: 15613314.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    215. Incidence of HIV superinfection following primary infection. JAMA. 2004 Sep 08; 292(10):1177-8. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Daar ES, Richman DD, Little SJ. PMID: 15353529.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    216. The prostate as a reservoir for HIV-1. AIDS. 2004 Jul 23; 18(11):1600-2. Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. PMID: 15238781.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    217. Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS. 2003 May 02; 17(7):F11-6. Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Brown AJ, Petropoulos CJ, Richman DD, Wong JK. PMID: 12700477.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    218. Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4819-24. Strain MC, Günthard HF, Havlir DV, Ignacio CC, Smith DM, Leigh-Brown AJ, Macaranas TR, Lam RY, Daly OA, Fischer M, Opravil M, Levine H, Bacheler L, Spina CA, Richman DD, Wong JK. PMID: 12684537.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    219. Fatal Saccharomyces cerevisiae aortic graft infection. J Clin Microbiol. 2002 Jul; 40(7):2691-2. Smith D, Metzgar D, Wills C, Fierer J. PMID: 12089311.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    220. Continue antiretroviral therapy during virologic failure? Clin Infect Dis. 2002 Feb 15; 34(4):553-6. Smith D, Wong J. PMID: 11797186.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    221. Viral pneumonia as a serious complication of etanercept therapy. Ann Intern Med. 2002 Jan 15; 136(2):174. Smith D, Letendre S. PMID: 11790076.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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