Loading...

James Brian Brewer

Title(s)Professor, Neurosciences
SchoolHealth Sciences
Address9500 Gilman Drive #0949
La Jolla CA 92093
Phone858-534-1237
vCardDownload vCard
    Other Positions
    Title(s)Professor, Neurosciences


    Collapse Biography 
    Collapse Education and Training
    Weizmann Institute of ScienceFulbright Scholar to Israel
    Stanford UniversityMD, PhD2000Medicine / Neuro.
    Missouri StateBS1992Biology/Psychology

    Collapse Overview 
    Collapse Overview
    Dr. Brewer is a neurologist and neuroscientist whose primary research interest is human memory. He has developed functional and structural magnetic resonance imaging (MRI) approaches to study memory processes in volunteers with healthy memory and in patients with memory impairment, such as cases caused by Alzheimer's disease (AD). Dr. Brewer has developed and applied advanced neuroimaging approaches for early detection of Alzheimer’s in the clinical setting and also as a measure of the efficacy of new drugs under development. He conducted studies that led to FDA and European regulatory clearance of a widely used tool for brain structure analysis that has been used to assess brain atrophy in over 80,000 clinical patients. Appointed in both Radiology and Neurosciences Departments, he directs the Imaging Core for the multi-institutional Alzheimer’s Disease Cooperative Study and the UCSD Shiley-Marcos Alzheimer’s Disease Research Center, overseeing the brain imaging of all enrolled subjects.
    Dr. Brewer received his medical and research degrees at Stanford Medical School, where he developed advanced structural and functional neuroimaging approaches for the study of human memory. He obtained neurology residency training at Johns Hopkins and then joined the faculty of UCSD, where he holds a joint appointment in the departments of Radiology and Neurosciences. He is director of the Shiley-Marcos Alzheimer’s Disease Research Center and directs the Imaging Core for multiple Alzheimer’s disease clinical trials.

    Dr. Brewer has developed and applied advanced neuroimaging approaches for early detection of Alzheimer’s in the clinical setting and also as a measure of the efficacy of new drugs under development. He conducted studies that led to FDA and international regulatory clearance of a widely used tool for brain structure analysis that has been used to assess brain atrophy in over 100,000 clinical patients.

    Collapse Research 
    Collapse Research Activities and Funding
    Multidisciplinary training in basic and translational Alzheimer's disease research
    NIH T32AG066596May 1, 2020 - Apr 30, 2025
    Role: Co-Principal Investigator
    UCSD Alzheimer's Disease Research Centers P30
    NIH P30AG062429May 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Study of Latinos Investigation of Neurocognitive Aging 2
    NIH R56AG048642Sep 1, 2015 - Apr 30, 2022
    Role: Co-Principal Investigator
    Longitudinal Cognitive ERP studies: Advancement for AD Clinical Trials
    NIH R01AG048252Sep 1, 2015 - Apr 30, 2021
    Role: Principal Investigator
    Sharing Clinical and Imaging Data from ADCS Clinical Trials through BIRN
    NIH R01AG034062Sep 1, 2011 - Aug 31, 2015
    Role: Principal Investigator
    Multimodal MRI Studies of Brain Structure and Function in PDD and AD
    NIH K02NS067427Dec 1, 2009 - Nov 30, 2015
    Role: Principal Investigator
    MRI Studies of MTL Structure and Function in MCI and AD
    NIH K23NS050305Dec 15, 2004 - Dec 31, 2009
    Role: Principal Investigator
    UCSD Alzheimer's Disease Research Center P50
    NIH P50AG005131Apr 1, 1997 - Aug 31, 1989
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 Jan 01; 78(1):102-113. Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. PMID: 33074286.
      View in: PubMed   Mentions: 1     Fields:    
    2. Noninvasive characterization of Alzheimer's disease by circulating, cell-free messenger RNA next-generation sequencing. Sci Adv. 2020 Dec; 6(50). Toden S, Zhuang J, Acosta AD, Karns AP, Salathia NS, Brewer JB, Wilcock DM, Aballi J, Nerenberg M, Quake SR, Ibarra A. PMID: 33298436.
      View in: PubMed   Mentions:    Fields:    
    3. Gene- and age-informed screening for preclinical Alzheimer's disease trials. Alzheimers Dement. 2020 Nov 23. Spencer BE, Digma LA, Jennings RG, Brewer JB. PMID: 33226723.
      View in: PubMed   Mentions:    Fields:    
    4. Assessment of genetic risk for improved clinical-neuropathological correlations. Acta Neuropathol Commun. 2020 09 10; 8(1):160. Spencer BE, Jennings RG, Fan CC, Brewer JB. PMID: 32912321.
      View in: PubMed   Mentions:    Fields:    
    5. Association of anticholinergic medications and AD biomarkers with incidence of MCI among cognitively normal older adults. Neurology. 2020 10 20; 95(16):e2295-e2304. Weigand AJ, Bondi MW, Thomas KR, Campbell NL, Galasko DR, Salmon DP, Sewell D, Brewer JB, Feldman HH, Delano-Wood L. PMID: 32878992.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial. JAMA Neurol. 2020 Sep 01; 77(9):1099-1109. Craft S, Raman R, Chow TW, Rafii MS, Sun CK, Rissman RA, Donohue MC, Brewer JB, Jenkins C, Harless K, Gessert D, Aisen PS. PMID: 32568367.
      View in: PubMed   Mentions: 6     Fields:    
    7. Community memory screening as a strategy for recruiting older adults into Alzheimer's disease research. Alzheimers Res Ther. 2020 06 30; 12(1):78. Peavy GM, Jenkins CW, Little EA, Gigliotti C, Calcetas A, Edland SD, Brewer JB, Galasko D, Salmon DP. PMID: 32605603.
      View in: PubMed   Mentions:    Fields:    
    8. Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau. Brain Commun. 2020; 2(1):fcaa025. Digma LA, Madsen JR, Rissman RA, Jacobs DM, Brewer JB, Banks SJ. PMID: 32337508.
      View in: PubMed   Mentions:
    9. Associations Between Microstructure, Amyloid, and Cognition in Amnestic Mild Cognitive Impairment and Dementia. J Alzheimers Dis. 2020; 73(1):347-357. Reas ET, Hagler DJ, Kuperman JM, Wierenga CE, Galasko D, White NS, Dale AM, Banks SJ, McEvoy LK, Brewer JB. PMID: 31796676.
      View in: PubMed   Mentions: 1     Fields:    
    10. Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139. Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    11. High-Throughput Mass Spectrometry Assay for Quantifying ß-Amyloid 40 and 42 in Cerebrospinal Fluid. Clin Chem. 2019 12; 65(12):1572-1580. Weber DM, Tran D, Goldman SM, Taylor SW, Ginns EI, Lagier RJ, Rissman RA, Brewer JB, Clarke NJ. PMID: 31628138.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Tau and atrophy: domain-specific relationships with cognition. Alzheimers Res Ther. 2019 07 27; 11(1):65. Digma LA, Madsen JR, Reas ET, Dale AM, Brewer JB, Banks SJ. PMID: 31351484.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial. JAMA Neurol. 2019 Jul 22. van Dyck CH, Nygaard HB, Chen K, Donohue MC, Raman R, Rissman RA, Brewer JB, Koeppe RA, Chow TW, Rafii MS, Gessert D, Choi J, Turner RS, Kaye JA, Gale SA, Reiman EM, Aisen PS, Strittmatter SM. PMID: 31329216.
      View in: PubMed   Mentions: 6     Fields:    
    14. Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial. JAMA Neurol. 2019 Jul 08. Schneider LS, Thomas RG, Hendrix S, Rissman RA, Brewer JB, Salmon DP, Oltersdorf T, Okuda T, Feldman HH. PMID: 31282954.
      View in: PubMed   Mentions: 3     Fields:    
    15. Distinct structural correlates of the dominant and nondominant languages in bilinguals with Alzheimer's disease (AD). Neuropsychologia. 2019 09; 132:107131. Smirnov DS, Stasenko A, Salmon DP, Galasko D, Brewer JB, Gollan TH. PMID: 31271821.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Combined Biomarker Prognosis of Mild Cognitive Impairment: An 11-Year Follow-Up Study in the Alzheimer's Disease Neuroimaging Initiative. J Alzheimers Dis. 2019; 68(4):1549-1559. Spencer BE, Jennings RG, Brewer JB. PMID: 30958366.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Trajectories of cognitive decline differ in hippocampal sclerosis and Alzheimer's disease. Neurobiol Aging. 2019 03; 75:169-177. Smirnov DS, Galasko D, Hansen LA, Edland SD, Brewer JB, Salmon DP. PMID: 30579145.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathol. 2019 02; 137(2):209-226. Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Schellenberg GD, Yaffe K, Sugrue LP, Dale AM, Posthuma D, Andreassen OA, Karch CM, Desikan RS. PMID: 30413934.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Microstructural brain changes track cognitive decline in mild cognitive impairment. Neuroimage Clin. 2018; 20:883-891. Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. PMID: 30290303.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial. JAMA Neurol. 2018 07 01; 75(7):834-841. Rafii MS, Tuszynski MH, Thomas RG, Barba D, Brewer JB, Rissman RA, Siffert J, Aisen PS. PMID: 29582053.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    21. Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults. Proc Natl Acad Sci U S A. 2018 04 03; 115(14):3686-3691. PMID: 29555771.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    22. Clinical-Neuropathological Correlations of Alzheimer's Disease and Related Dementias in Latino Volunteers. J Alzheimers Dis. 2018; 66(4):1539-1548. Soria JA, Huisa BN, Edland SD, Litvan I, Peavy GM, Salmon DP, Hansen LA, Galasko DR, Brewer JB, González HM, Rissman RA. PMID: 30412501.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 01; 135(1):85-93. Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS. PMID: 29177679.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    24. Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease. Alzheimers Res Ther. 2017 Aug 02; 9(1):55. PMID: 28764771.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. A phase 3 trial of IV immunoglobulin for Alzheimer disease. Neurology. 2017 May 02; 88(18):1768-1775. PMID: 28381506.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    26. NPTX2 and cognitive dysfunction in Alzheimer's Disease. Elife. 2017 03 23; 6. Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF. PMID: 28440221.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    27. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 03; 14(3):e1002258. PMID: 28323831.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    28. Abnormalities in hippocampal volume of glioma patients prior to radiotherapy. Acta Oncol. 2017 Mar; 56(3):427-430. PMID: 28156177.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. I know I've seen you before: Distinguishing recent-single-exposure-based familiarity from pre-existing familiarity. Brain Res. 2017 03 01; 1658:11-24. PMID: 28073651.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Cerebral Cortex Regions Selectively Vulnerable to Radiation Dose-Dependent Atrophy. Int J Radiat Oncol Biol Phys. 2017 04 01; 97(5):910-918. PMID: 28333012.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    31. PET Imaging of Tau Pathology and Relationship to Amyloid, Longitudinal MRI, and Cognitive Change in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI). J Alzheimers Dis. 2017; 60(2):439-450. PMID: 28946567.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    32. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):152-164. PMID: 27899424.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    33. Radiation Dose-Dependent Hippocampal Atrophy Detected With Longitudinal Volumetric Magnetic Resonance Imaging. Int J Radiat Oncol Biol Phys. 2017 02 01; 97(2):263-269. PMID: 28068234.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    34. Demonstration of safety of intravenous immunoglobulin in geriatric patients in a long-term, placebo-controlled study of Alzheimer's disease. Alzheimers Dement (N Y). 2016 Jun; 2(2):131-139. PMID: 29067300.
      View in: PubMed   Mentions:
    35. Dissociation of Down syndrome and Alzheimer's disease effects with imaging. Alzheimers Dement (N Y). 2016 Jun; 2(2):69-81. Matthews DC, Lukic AS, Andrews RD, Marendic B, Brewer J, Rissman RA, Mosconi L, Strother SC, Wernick MN, Mobley WC, Ness S, Schmidt ME, Rafii MS. PMID: 28642933.
      View in: PubMed   Mentions:
    36. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 06 01; 73(6):691-7. PMID: 27088644.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    37. Radiation sparing of cerebral cortex in brain tumor patients using quantitative neuroimaging. Radiother Oncol. 2016 Jan; 118(1):29-34. PMID: 26806266.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    38. Dose-Dependent Cortical Thinning After Partial Brain Irradiation in High-Grade Glioma. Int J Radiat Oncol Biol Phys. 2016 Feb 01; 94(2):297-304. PMID: 26853338.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    39. The down syndrome biomarker initiative (DSBI) pilot: proof of concept for deep phenotyping of Alzheimer's disease biomarkers in down syndrome. Front Behav Neurosci. 2015; 9:239. PMID: 26441570.
      View in: PubMed   Mentions:
    40. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Neurology. 2015 Oct 20; 85(16):1383-91. PMID: 26362286.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCTClinical Trials
    41. Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. PMID: 26194310.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    42. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 09; 131(23):2061-2069. PMID: 25862742.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    43. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry. 2015 Dec; 20(12):1588-95. PMID: 25687773.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    44. Mean signal and response time influences on multivoxel signals of contextual retrieval in the medial temporal lobe. Brain Behav. 2015 Feb; 5(2):e00302. PMID: 25646149.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease. Alzheimers Dement. 2014 Jul; 10(4):421-429.e3. PMID: 24985687.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    46. Prospective longitudinal MRI study of brain volumes and diffusion changes during the first year after moderate to severe traumatic brain injury. Neuroimage Clin. 2014; 5:128-40. PMID: 25068105.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    47. Elaboration versus suppression of cued memories: influence of memory recall instruction and success on parietal lobe, default network, and hippocampal activity. PLoS One. 2014; 9(2):e89037. PMID: 24586492.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. The role of clusterin in amyloid-ß-associated neurodegeneration. JAMA Neurol. 2014 Feb; 71(2):180-7. PMID: 24378367.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    49. Neuropsychiatric symptoms and regional neocortical atrophy in mild cognitive impairment and Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2014 Mar; 29(2):159-65. PMID: 24164929.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    50. Operationalizing hippocampal volume as an enrichment biomarker for amnestic mild cognitive impairment trials: effect of algorithm, test-retest variability, and cut point on trial cost, duration, and sample size. Neurobiol Aging. 2014 Apr; 35(4):808-18. PMID: 24211008.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    51. Heart fatty acid binding protein and Aß-associated Alzheimer's neurodegeneration. Mol Neurodegener. 2013 Oct 02; 8:39. PMID: 24088526.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    52. Imbalance of incidental encoding across tasks: an explanation for non-memory-related hippocampal activations? J Exp Psychol Gen. 2013 Nov; 142(4):1171-9. PMID: 23773160.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    53. An expanded role for neuroimaging in the evaluation of memory impairment. AJNR Am J Neuroradiol. 2013 Nov-Dec; 34(11):2075-82. PMID: 23764728.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    54. Effortful retrieval reduces hippocampal activity and impairs incidental encoding. Hippocampus. 2013 May; 23(5):367-79. PMID: 23378272.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    55. Erratum: search-related suppression of hippocampus and default network activity during associative memory retrieval. Front Hum Neurosci. 2013; 7:2. PMID: 23355818.
      View in: PubMed   Mentions:
    56. Parietal and frontal contributions to episodic encoding of location. Behav Brain Res. 2013 Apr 15; 243:16-20. PMID: 23295390.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    57. Retrieval search and strength evoke dissociable brain activity during episodic memory recall. J Cogn Neurosci. 2013 Feb; 25(2):219-33. PMID: 23190328.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    58. Apolipoprotein E epsilon4 does not modulate amyloid-ß-associated neurodegeneration in preclinical Alzheimer disease. AJNR Am J Neuroradiol. 2013 Mar; 34(3):505-10. PMID: 22976236.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    59. Biomarkers for the clinical evaluation of the cognitively impaired elderly: amyloid is not enough. Imaging Med. 2012 Jun; 4(3):343-357. PMID: 23420460.
      View in: PubMed   Mentions:
    60. Amyloid-ß--associated clinical decline occurs only in the presence of elevated P-tau. Arch Neurol. 2012 Jun; 69(6):709-13. PMID: 22529247.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    61. The path to memory is guided by strategy: distinct networks are engaged in associative encoding under visual and verbal strategy and influence memory performance in healthy and impaired individuals. J Cogn Neurosci. 2012 Jun; 24(6):1398-410. PMID: 22390467.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    62. CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner. Brain Imaging Behav. 2012 Mar; 6(1):16-26. Murphy EA, Roddey JC, McEvoy LK, Holland D, Hagler DJ, Dale AM, Brewer JB. PMID: 21892657.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    63. Interregional correlations in Parkinson disease and Parkinson-related dementia with resting functional MR imaging. Radiology. 2012 Apr; 263(1):226-34. PMID: 22371611.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    64. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. PMID: 22343285.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    65. Search-Related Suppression of Hippocampus and Default Network Activity during Associative Memory Retrieval. Front Hum Neurosci. 2011; 5:112. Reas ET, Gimbel SI, Hales JB, Brewer JB. PMID: 22046159.
      View in: PubMed   Mentions:
    66. Amyloid-ß associated volume loss occurs only in the presence of phospho-tau. Ann Neurol. 2011 Oct; 70(4):657-61. PMID: 22002658.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    67. Predicting MCI outcome with clinically available MRI and CSF biomarkers. Neurology. 2011 Oct 25; 77(17):1619-28. PMID: 21998317.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    68. Stability of resting fMRI interregional correlations analyzed in subject-native space: a one-year longitudinal study in healthy adults and premanifest Huntington's disease. Neuroimage. 2012 Feb 01; 59(3):2452-63. Seibert TM, Majid DS, Aron AR, Corey-Bloom J, Brewer JB. PMID: 21945695.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    69. Default network correlations analyzed on native surfaces. J Neurosci Methods. 2011 Jun 15; 198(2):301-11. Seibert TM, Brewer JB. PMID: 21514321.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    70. Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis. Radiology. 2011 Jun; 259(3):834-43. PMID: 21471273.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    71. Reaction time, memory strength, and fMRI activity during memory retrieval: Hippocampus and default network are differentially responsive during recollection and familiarity judgments. Cogn Neurosci. 2011 Mar; 2(1):19-23. Gimbel SI, Brewer JB. PMID: 21278912.
      View in: PubMed   Mentions: 7     Fields:    
    72. Early parietal response in episodic retrieval revealed with MEG. Hum Brain Mapp. 2011 Feb; 32(2):171-81. Seibert TM, Hagler DJ, Brewer JB. PMID: 20623759.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    73. The timing of associative memory formation: frontal lobe and anterior medial temporal lobe activity at associative binding predicts memory. J Neurophysiol. 2011 Apr; 105(4):1454-63. Hales JB, Brewer JB. PMID: 21248058.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    74. Parietal activity in episodic retrieval measured by fMRI and MEG. Neuroimage. 2011 Mar 15; 55(2):788-93. Seibert TM, Gimbel SI, Hagler DJ, Brewer JB. PMID: 21134473.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    75. Functional brain imaging in the clinical assessment of consciousness. PLoS Biol. 2010 Nov 30; 8(11):e1000548. Rafii MS, Brewer JB. PMID: 21151340.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    76. Quantitative structural MRI for early detection of Alzheimer's disease. Expert Rev Neurother. 2010 Nov; 10(11):1675-88. McEvoy LK, Brewer JB. PMID: 20977326.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    77. Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease. Radiology. 2010 Sep; 256(3):932-42. Karow DS, McEvoy LK, Fennema-Notestine C, Hagler DJ, Jennings RG, Brewer JB, Hoh CK, Dale AM. PMID: 20720076.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    78. Activity in the hippocampus and neocortical working memory regions predicts successful associative memory for temporally discontiguous events. Neuropsychologia. 2010 Sep; 48(11):3351-9. Hales JB, Brewer JB. PMID: 20667491.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    79. Six-month atrophy in MTL structures is associated with subsequent memory decline in elderly controls. Neuroimage. 2010 Dec; 53(4):1310-7. Murphy EA, Holland D, Donohue M, McEvoy LK, Hagler DJ, Dale AM, Brewer JB. PMID: 20633660.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    80. Neuroimaging enrichment strategy for secondary prevention trials in Alzheimer disease. Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):269-77. McEvoy LK, Edland SD, Holland D, Hagler DJ, Roddey JC, Fennema-Notestine C, Salmon DP, Koyama AK, Aisen PS, Brewer JB, Dale AM. PMID: 20683184.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    81. Going their separate ways: dissociation of hippocampal and dorsolateral prefrontal activation during episodic retrieval and post-retrieval processing. J Cogn Neurosci. 2010 Mar; 22(3):513-25. Israel SL, Seibert TM, Black ML, Brewer JB. PMID: 19301994.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    82. CSF biomarkers in prediction of cerebral and clinical change in mild cognitive impairment and Alzheimer's disease. J Neurosci. 2010 Feb 10; 30(6):2088-101. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM. PMID: 20147537.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    83. Early stages of figure-ground segregation during perception of the face-vase. J Cogn Neurosci. 2011 Apr; 23(4):880-95. Pitts MA, Martínez A, Brewer JB, Hillyard SA. PMID: 20146604.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    84. Brain atrophy in healthy aging is related to CSF levels of Aß1-42. Cereb Cortex. 2010 Sep; 20(9):2069-79. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Blennow K, Brewer JB, Dale AM. PMID: 20051356.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    85. Subregional neuroanatomical change as a biomarker for Alzheimer's disease. Proc Natl Acad Sci U S A. 2009 Dec 08; 106(49):20954-9. Holland D, Brewer JB, Hagler DJ, Fennema-Notestine C, Fenema-Notestine C, Dale AM. PMID: 19996185.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    86. One-year brain atrophy evident in healthy aging. J Neurosci. 2009 Dec 02; 29(48):15223-31. Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM. PMID: 19955375.
      View in: PubMed   Mentions: 175     Fields:    Translation:Humans
    87. Regional rates of neocortical atrophy from normal aging to early Alzheimer disease. Neurology. 2009 Aug 11; 73(6):457-65. McDonald CR, McEvoy LK, Gharapetian L, Fennema-Notestine C, Hagler DJ, Holland D, Koyama A, Brewer JB, Dale AM. PMID: 19667321.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    88. Dissociation of frontal and medial temporal lobe activity in maintenance and binding of sequentially presented paired associates. J Cogn Neurosci. 2009 Jul; 21(7):1244-54. Hales JB, Israel SL, Swann NC, Brewer JB. PMID: 18752401.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    89. High-throughput, fully automated volumetry for prediction of MMSE and CDR decline in mild cognitive impairment. Alzheimer Dis Assoc Disord. 2009 Apr-Jun; 23(2):139-45. Kovacevic S, Rafii MS, Brewer JB. PMID: 19474571.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    90. Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment. Radiology. 2009 Apr; 251(1):195-205. McEvoy LK, Fennema-Notestine C, Roddey JC, Hagler DJ, Holland D, Karow DS, Pung CJ, Brewer JB, Dale AM. PMID: 19201945.
      View in: PubMed   Mentions: 124     Fields:    Translation:Humans
    91. Fully-automated volumetric MRI with normative ranges: translation to clinical practice. Behav Neurol. 2009; 21(1):21-8. Brewer JB. PMID: 19847042.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    92. Applications of neuroimaging to disease-modification trials in Alzheimer's disease. Behav Neurol. 2009; 21(1):129-36. Fleisher AS, Donohue M, Chen K, Brewer JB, Aisen PS. PMID: 19847051.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    93. Fully-automated quantification of regional brain volumes for improved detection of focal atrophy in Alzheimer disease. AJNR Am J Neuroradiol. 2009 Mar; 30(3):578-80. Brewer JB, Magda S, Airriess C, Smith ME. PMID: 19112065.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    94. Item memory, source memory, and the medial temporal lobe: concordant findings from fMRI and memory-impaired patients. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9351-6. Gold JJ, Smith CN, Bayley PJ, Shrager Y, Brewer JB, Stark CE, Hopkins RO, Squire LR. PMID: 16751272.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    95. Imaging the medial temporal lobe: exploring new dimensions. Trends Cogn Sci. 2002 May 01; 6(5):217-223. Brewer JB, Moghekar A. PMID: 11983585.
      View in: PubMed   Mentions: 12     Fields:    
    96. Material-specific lateralization in the medial temporal lobe and prefrontal cortex during memory encoding. Brain. 2001 Sep; 124(Pt 9):1841-54. Golby AJ, Poldrack RA, Brewer JB, Spencer D, Desmond JE, Aron AP, Gabrieli JD. PMID: 11522586.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    97. Level of sustained entorhinal activity at study correlates with subsequent cued-recall performance: a functional magnetic resonance imaging study with high acquisition rate. Hippocampus. 1999; 9(1):35-44. Fernández G, Brewer JB, Zhao Z, Glover GH, Gabrieli JD. PMID: 10088898.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    98. Making memories: brain activity that predicts how well visual experience will be remembered. Science. 1998 Aug 21; 281(5380):1185-7. Brewer JB, Zhao Z, Desmond JE, Glover GH, Gabrieli JD. PMID: 9712581.
      View in: PubMed   Mentions: 237     Fields:    Translation:Humans
    99. Images of medial temporal lobe functions in human learning and memory. Neurobiol Learn Mem. 1998 Jul-Sep; 70(1-2):275-83. Gabrieli JD, Brewer JB, Poldrack RA. PMID: 9753602.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    100. Focusing in on the medial temporal lobe. Mol Psychiatry. 1997 Oct-Nov; 2(6):430-1, 427-8. Brewer JB, Gabrieli JD. PMID: 9399679.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    101. Separate neural bases of two fundamental memory processes in the human medial temporal lobe. Science. 1997 Apr 11; 276(5310):264-6. Gabrieli JD, Brewer JB, Desmond JE, Glover GH. PMID: 9092477.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    James's Networks
    Concepts (258)
    Derived automatically from this person's publications.
    _
    Co-Authors (104)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _