Loading...

Stephen Spector

Title(s)Professor, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0672
La Jolla CA 92093
Phone858-534-7055
Emailsaspector@ucsd.edu
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Tufts University School of Medicine, Boston, MAMD05/1975Medicine
    University of California, San Francisco, San Francisco, CA06/1977Pediatric Residency
    University of California, San Francisco, San Francisco, CA06/1978Fellow, Neonatogy and Pediatric Infectious Diseases
    University of California, San Diego, La Jolla, CA06/1979NIH Fellow, Pediatric Infectious Diseases
    Collapse Awards and Honors
    Tufts University School of Medicine1972NIH Research Fellow in Immunology
    UCSD1978  - 1979NIH Fellow in Infectious Diseases
    NIAID1995  - 2006Chair, Executive Committe Pediatric AIDS Clinical Trials Group
    2000  - presBest Doctors in America
    Soth Africa Embassy2006Honored by South African Embassy to U.S. for contributions to halting HIV/AIDS epidemic
    NIAID2006Honored by PACTG for exceptional contributions and leadership
    American Association of Physicians 2009Elected to American Association of Physicians
    UCSD.Rady Children's Hospital2010Recipient of Rady Children’s Hospital San Diego Research Award
    Children's Hospital of Philadelphia2010Gertrude and Herman Silver Award in Recognition of work on behalf of children, adolescents and famil

    Collapse Overview 
    Collapse Overview
    Dr. Spector, a world leader in HIV research for more than 25 years, is Distinguished Professor of Pediatrics, the Chief of the Division of Pediatric Infectious Diseases and Director of the UCSD Mother-Child-Adolescent HIV Program. His research has used molecular and Immunologic approaches to study host-virus interactions of human cytomegalovirus (CMV) and human immunodeficiency virus type-1 (HIV-1) with a particular emphasis developing novel approaches for the detection, treatment and eradication of persistent viruses. Current CMV related research is examining the role of CMV in endothelial cell inflammation and the development of cardiovascular diseases. The laboratory has been involved with HIV/AIDS research since the beginning of the epidemic. Current research examines HIV pathogenesis with a particular emphasis on host-virus interactions, and the associations of host genetic variants on HIV diseases progression and HIV-related diseases including CNS impairment in children and adults. The laboratory’s interest in the identification of host factors that affect HIV pathogenesis led us to the novel finding that during permissive infection, HIV down-regulates autophagy to promote its own replication, and the induction of autophagy (using mTOR inhibitors as well as vitamin D3) inhibits HIV replication. The laboratory has also identified specific host genetic variants that are associated with mother-to-child transmission, HIV disease progression, and antiretroviral pharmacokinetics and adverse effects. This research has led to our examining the association of host factors that control HIV replication with the goal of identifying novel strategies to eradicate HIV from those infected.

    Collapse Research 
    Collapse Research Activities and Funding
    Nanopeptide Targeting of HIV-CNS Reservoirs without Reactivation
    NIH/NINDS R01NS104015May 1, 2017 - Feb 28, 2022
    Role: Principal Investigator
    Role of CMV in Heart Disease of HIV-Infected Women and Perinatally Infected Youth
    NIH/NHLBI R56HL125028Sep 12, 2014 - Aug 31, 2015
    Role: Principal Investigator
    Modulating Autophagy to Eradicate HIV-1 from CNS Reservoirs
    NIH/NINDS R01NS084912May 1, 2013 - Apr 30, 2018
    Role: Principal Investigator
    Host Genetic Factors Associated with CNS Disease of HIV-Infected Children
    NIH/NINDS R01NS077874Aug 1, 2011 - Mar 31, 2016
    Role: Principal Investigator
    Vitamin D Inhibition of HIV and M. Tuberculosis Coinfection in Macrophages
    NIH/NIAID R21AI084573Jul 21, 2009 - Jun 30, 2011
    Role: Principal Investigator
    HIV CENTERS FOR UNDEREPRESENTED POPULATIONS IN RESEARCH CTU (HIV CURE CTU)
    NIH/NIAID UM1AI069536Jan 1, 2007 - Nov 30, 2020
    Role: Principal Investigator
    University of California, San Diego Clinical Trial Unit
    NIH/NIAID U01AI069536Jan 1, 2007 - Nov 30, 2013
    Role: Principal Investigator
    San Diego EXPORT Comprehensive NCMHD Research Center
    NIH P60MD000220Sep 30, 2002 - Apr 30, 2013
    Role: Co-Investigator
    San Diego Export: An University Community Partnership E*
    NIH P60MD000263Sep 30, 2002 - Aug 31, 2008
    Role: Co-Investigator
    ADOLESCENT MEDICINE TRIALS UNIT (AMTU)
    NIH/NICHD U01HD040464Apr 16, 2001 - Feb 28, 2007
    Role: Principal Investigator
    Center for AIDS Research
    NIH/NIAID P30AI036214Apr 1, 1997 - May 31, 2012
    Role: Co-Investigator
    Pediatric ACTG Coordinating and Operations Center
    NIH/NIAID U01AI041089Mar 1, 1997 - Feb 28, 2007
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Jan 27, 1997 - Nov 30, 2010
    Role: Co-Investigator
    FACTORS IN PEDIATRIC AIDS TRANSMISSION AND PATHOGENESIS
    NIH/NIAID R01AI039004Sep 30, 1995 - Feb 28, 2006
    Role: Principal Investigator
    MOLECULAR INTERACTION OF HIV HCMV
    NIH/NIAID R01AI028270Apr 1, 1989 - Mar 31, 1994
    Role: Principal Investigator
    Pediatric AIDS Clinical Trials Group
    NIH/NIAID U01AI027563Sep 30, 1988 - Feb 28, 2007
    Role: Principal Investigator
    SAN DIEGO AIDS CLINICAL TRIAL UNIT
    NIH/NIAID U01AI027670Jun 30, 1986 - Mar 31, 1992
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Raltegravir (RAL) in Neonates: Dosing, Pharmacokinetics (PK), and Safety in HIV-1-Exposed Neonates at Risk of Infection (IMPAACT P1110). J Acquir Immune Defic Syndr. 2020 May 01; 84(1):70-77. Clarke DF, Acosta EP, Cababasay M, Wang J, Chain A, Teppler H, Popson S, Graham B, Smith B, Hazra R, Calabrese K, Bryson Y, Spector SA, Lommerse J, Mirochnick M. PMID: 31913995.
      View in: PubMed   Mentions:    Fields:    
    2. Live Respiratory Syncytial Virus Attenuated by M2-2 Deletion and Stabilized Temperature Sensitivity Mutation 1030s Is a Promising Vaccine Candidate in Children. J Infect Dis. 2020 Feb 03; 221(4):534-543. McFarland EJ, Karron RA, Muresan P, Cunningham CK, Libous J, Perlowski C, Thumar B, Gnanashanmugam D, Moye J, Schappell E, Barr E, Rexroad V, Fearn L, Spector SA, Aziz M, Cielo M, Beneri C, Wiznia A, Luongo C, Collins P, Buchholz UJ. PMID: 31758177.
      View in: PubMed   Mentions: 1     Fields:    
    3. TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function. mBio. 2019 11 12; 10(6). Campbell GR, To RK, Spector SA. PMID: 31719184.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Birth Prevalence of Congenital Cytomegalovirus Infection in HIV-Exposed Uninfected Children in the Era of Combination Antiretroviral Therapy. J Pediatr. 2020 Jan; 216:82-87.e2. Purswani MU, Russell JS, Dietrich M, Malee K, Spector SA, Williams PL, Frederick T, Burchett S, Redmond S, Hoffman HJ, Torre P, Lee S, Rice ML, Yao TJ. PMID: 31668479.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis. PLoS Med. 2019 09; 16(9):e1002907. Aibana O, Huang CC, Aboud S, Arnedo-Pena A, Becerra MC, Bellido-Blasco JB, Bhosale R, Calderon R, Chiang S, Contreras C, Davaasambuu G, Fawzi WW, Franke MF, Galea JT, Garcia-Ferrer D, Gil-Fortuño M, Gomila-Sard B, Gupta A, Gupte N, Hussain R, Iborra-Millet J, Iqbal NT, Juan-Cerdán JV, Kinikar A, Lecca L, Mave V, Meseguer-Ferrer N, Montepiedra G, Mugusi FM, Owolabi OA, Parsonnet J, Roach-Poblete F, Romeu-García MA, Spector SA, Sudfeld CR, Tenforde MW, Togun TO, Yataco R, Zhang Z, Murray MB. PMID: 31509529.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Establishing Dosing Recommendations for Efavirenz in HIV/TB-Coinfected Children Younger Than 3 Years. J Acquir Immune Defic Syndr. 2019 08 01; 81(4):473-480. Bwakura Dangarembizi M, Samson P, Capparelli EV, Moore CB, Jean-Philippe P, Spector SA, Chakhtoura N, Benns A, Zimmer B, Purdue L, Jackson C, Wallis C, Libous JL, Chadwick EG. PMID: 31241542.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    7. Markers of Bone Mineral Metabolism and Cardiac Structure and Function in Perinatally HIV-Infected and HIV-Exposed but Uninfected Children and Adolescents. J Acquir Immune Defic Syndr. 2019 06 01; 81(2):238-246. Margossian R, Williams PL, Yu W, Jacobson DL, Geffner ME, DiMeglio LA, Van Dyke RB, Spector SA, Schuster GU, Stephensen CB, Miller TL, Lipshultz SE. PMID: 30865170.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. Cell Death Dis. 2019 05 29; 10(6):419. Zhang G, Luk BT, Wei X, Campbell GR, Fang RH, Zhang L, Spector SA. PMID: 31142734.
      View in: PubMed   Mentions:    Fields:    
    9. Vaccine Strain Varicella Infection in an Infant With Previously Undiagnosed Perinatal Human Immunodeficiency Type-1 Infection. Pediatr Infect Dis J. 2019 04; 38(4):413-415. Farnaes L, Coufal NG, Spector SA. PMID: 30882735.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease. Open Forum Infect Dis. 2019 May; 6(5):ofz113. Garg A, Gianella S, Nakazawa M, Trout R, Spector SA. PMID: 31139667.
      View in: PubMed   Mentions:
    11. DIABLO/SMAC mimetics selectively kill HIV-1-infected resting memory CD4+ T cells: a potential role in a cure strategy for HIV-1 infection. Autophagy. 2019 04; 15(4):744-746. Campbell GR, Spector SA. PMID: 30653393.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Human immunodeficiency virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia. Glia. 2019 05; 67(5):802-824. Rawat P, Teodorof-Diedrich C, Spector SA. PMID: 30582668.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Human Immunodeficiency Virus Type 1 gp120 and Tat Induce Mitochondrial Fragmentation and Incomplete Mitophagy in Human Neurons. J Virol. 2018 11 15; 92(22). Teodorof-Diedrich C, Spector SA. PMID: 30158296.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells. Cell Host Microbe. 2018 11 14; 24(5):689-702.e7. Campbell GR, Bruckman RS, Chu YL, Trout RN, Spector SA. PMID: 30344003.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. T-Cell-Mimicking Nanoparticles Can Neutralize HIV Infectivity. Adv Mater. 2018 Nov; 30(45):e1802233. Wei X, Zhang G, Ran D, Krishnan N, Fang RH, Gao W, Spector SA, Zhang L. PMID: 30252965.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Induction of a Na+/K+-ATPase-dependent form of autophagy triggers preferential cell death of human immunodeficiency virus type-1-infected macrophages. Autophagy. 2018; 14(8):1359-1375. Zhang G, Luk BT, Hamidy M, Zhang L, Spector SA. PMID: 29962265.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate With Deletion of RNA Synthesis Regulatory Protein M2-2 is Highly Immunogenic in Children. J Infect Dis. 2018 04 11; 217(9):1347-1355. McFarland EJ, Karron RA, Muresan P, Cunningham CK, Valentine ME, Perlowski C, Thumar B, Gnanashanmugam D, Siberry GK, Schappell E, Barr E, Rexroad V, Yogev R, Spector SA, Aziz M, Patel N, Cielo M, Luongo C, Collins PL, Buchholz UJ. PMID: 29509911.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children. J Infect Dis. 2018 04 11; 217(9):1338-1346. Buchholz UJ, Cunningham CK, Muresan P, Gnanashanmugam D, Sato P, Siberry GK, Rexroad V, Valentine M, Perlowski C, Schappell E, Thumar B, Luongo C, Barr E, Aziz M, Yogev R, Spector SA, Collins PL, McFarland EJ, Karron RA. PMID: 29509929.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    19. Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. J Biol Chem. 2018 04 20; 293(16):5808-5820. Campbell GR, Bruckman RS, Herns SD, Joshi S, Durden DL, Spector SA. PMID: 29475942.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. A Phase II/III Trial of Lopinavir/Ritonavir Dosed According to the WHO Pediatric Weight Band Dosing Guidelines. Pediatr Infect Dis J. 2018 02; 37(2):e29-e35. Pinto JA, Capparelli EV, Warshaw M, Zimmer B, Cressey TR, Spector SA, Qin M, Smith B, Siberry GK, Mirochnick M. PMID: 29088027.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    21. Comparison of the QuantiFERON TB Gold In-tube Assay With Tuberculin Skin Test for the Diagnosis of Latent Tuberculosis Infection Among HIV-infected and Uninfected Children. Pediatr Infect Dis J. 2017 Dec; 36(12):e317-e321. Dehority W, Viani RM, Araneta MRG, Lopez G, Spector SA. PMID: 29140946.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Associations of Low Vitamin D and Elevated Parathyroid Hormone Concentrations With Bone Mineral Density in Perinatally HIV-Infected Children. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):33-42. Jacobson DL, Stephensen CB, Miller TL, Patel K, Chen JS, Van Dyke RB, Mirza A, Schuster GU, Hazra R, Ellis A, Brummel SS, Geffner ME, Silio M, Spector SA, DiMeglio LA. PMID: 28797019.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Changes in Cardiovascular Disease Risk Factors With Immediate Versus Deferred Antiretroviral Therapy Initiation Among HIV-Positive Participants in the START (Strategic Timing of Antiretroviral Treatment) Trial. J Am Heart Assoc. 2017 May 22; 6(5). Baker JV, Sharma S, Achhra AC, Bernardino JI, Bogner JR, Duprez D, Emery S, Gazzard B, Gordin J, Grandits G, Phillips AN, Schwarze S, Soliman EZ, Spector SA, Tambussi G, Lundgren J. PMID: 28533305.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infection. AIDS. 2017 05 15; 31(8):1129-1136. Bolton Moore C, Capparelli EV, Samson P, Bwakura-Dangarembizi M, Jean-Philippe P, Worrell C, Heckman B, Purdue L, Spector SA, Benns A, Borkowsky W, Loftis A, Hawkins E, Wallis C, Chadwick EG. PMID: 28323755.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Human Immunodeficiency Virus Type-1 Myeloid Derived Suppressor Cells Inhibit Cytomegalovirus Inflammation through Interleukin-27 and B7-H4. Sci Rep. 2017 03 24; 7:44485. Garg A, Trout R, Spector SA. PMID: 28338007.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. HIV cure strategists: ignore the central nervous system at your patients' peril. AIDS. 2017 01 02; 31(1):167-168. Spector SA, Rappaport J. PMID: 27898594.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children. Medicine (Baltimore). 2016 Sep; 95(36):e4733. Spector SA, Brummel SS, Nievergelt CM, Maihofer AX, Singh KK, Purswani MU, Williams PL, Hazra R, Van Dyke R, Seage GR. PMID: 27603370.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Brief Report: APOL1 Renal Risk Variants Are Associated With Chronic Kidney Disease in Children and Youth With Perinatal HIV Infection. J Acquir Immune Defic Syndr. 2016 09 01; 73(1):63-8. Purswani MU, Patel K, Winkler CA, Spector SA, Hazra R, Seage GR, Mofenson L, Karalius B, Scott GB, Van Dyke RB, Kopp JB. PMID: 27035887.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Development and characterization of a human microglia cell model of HIV-1 infection. J Neurovirol. 2017 02; 23(1):33-46. Rawat P, Spector SA. PMID: 27538994.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    30. Associations of Genetically Determined Continental Ancestry With CD4+ Count and Plasma HIV-1 RNA Beyond Self-Reported Race and Ethnicity. J Acquir Immune Defic Syndr. 2016 Apr 15; 71(5):544-50. Brummel SS, Singh KK, Maihofer AX, Farhad M, Qin M, Fenton T, Nievergelt CM, Spector SA. PMID: 26536313.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    31. Antiretroviral Drug Resistance Among Children and Youth in the United States With Perinatal HIV. Clin Infect Dis. 2016 07 01; 63(1):133-137. Van Dyke RB, Patel K, Kagan RM, Karalius B, Traite S, Meyer WA, Tassiopoulos KK, Seage GR, Seybolt LM, Burchett S, Hazra R, Lurie RH, Yogev R, Sanders MA, Malee K, Hunter S, Shearer W, Paul M, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Garvie P, Blood J, Burchett S, Karthas N, Kammerer B, Wiznia A, Burey M, Nozyce M, Dieudonne A, Bettica L, Adubato S, Chen J, Bulkley MG, Ivey L, Grant M, Knapp K, Allison K, Wilkins M, Acevedo-Flores M, Rios H, Olivera V, Silio M, Jones M, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Katai A, Dunn J, Paul S, Scott G, Bryan P, Willen E. PMID: 27056398.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    32. Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children. PLoS One. 2016; 11(3):e0151364. Singh KK, Qin M, Brummel SS, Angelidou K, Trout RN, Fenton T, Spector SA. PMID: 26983081.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    33. Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants. PLoS One. 2016; 11(2):e0148649. Gupta A, Montepiedra G, Gupte A, Zeldow B, Jubulis J, Detrick B, Violari A, Madhi S, Bobat R, Cotton M, Mitchell C, Spector S. PMID: 26872154.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    34. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. PMID: 26799652.
      View in: PubMed   Mentions: 1105     Fields:    Translation:HumansAnimals
    35. Prevalence and Persistence of Varicella Antibodies in Previously Immunized Children and Youth With Perinatal HIV-1 Infection. Clin Infect Dis. 2016 Jan 01; 62(1):106-114. Purswani MU, Karalius B, Yao TJ, Schmid DS, Burchett SK, Siberry GK, Patel K, Van Dyke RB, Yogev R, Lurie RH, Yogev R, Sanders MA, Malee K, Hunter S, Shearer W, Paul M, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Garvie P, Blood J, Burchett S, Karthas N, Kammerer B, Wiznia A, Burey M, Nozyce M, Dieudonne A, Bettica L, Adubato S, Chen J, Bulkley MG, Ivey L, Grant M, Knapp K, Allison K, Wilkins M, Acevedo-Flores M, Rios H, Olivera V, Silio M, Jones M, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Katai A, Dunn J, Paul S, Scott G, Bryan P, Willen E. PMID: 26385992.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration. PLoS Pathog. 2015 Jun; 11(6):e1005018. Campbell GR, Rawat P, Bruckman RS, Spector SA. PMID: 26115100.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    37. Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth. PLoS One. 2015; 10(3):e0118567. Curtis DJ, Muresan P, Nachman S, Fenton T, Richardson KM, Dominguez T, Flynn PM, Spector SA, Cunningham CK, Bloom A, Weinberg A. PMID: 25785995.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsCTClinical Trials
    38. Pharmacokinetics and 48-Week Safety and Efficacy of Raltegravir for Oral Suspension in Human Immunodeficiency Virus Type-1-Infected Children 4 Weeks to 2 Years of Age. J Pediatric Infect Dis Soc. 2015 Dec; 4(4):e76-83. Nachman S, Alvero C, Acosta EP, Teppler H, Homony B, Graham B, Fenton T, Xu X, Rizk ML, Spector SA, Frenkel LM, Worrell C, Handelsman E, Wiznia A. PMID: 26582887.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    39. Single high-dose vitamin D at birth corrects vitamin D deficiency in infants in Mexico. Int J Food Sci Nutr. 2015 May; 66(3):336-41. Moodley A, Spector SA. PMID: 25582182.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Infant peripheral blood repetitive element hypomethylation associated with antiretroviral therapy in utero. Epigenetics. 2015; 10(8):708-16. Marsit CJ, Brummel SS, Kacanek D, Seage GR, Spector SA, Armstrong DA, Lester BM, Rich K. PMID: 26067216.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    41. Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1. J Biol Chem. 2015 Feb 20; 290(8):5028-40. Campbell GR, Bruckman RS, Chu YL, Spector SA. PMID: 25540204.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsCTClinical Trials
    42. Raltegravir pharmacokinetics in neonates following maternal dosing. J Acquir Immune Defic Syndr. 2014 Nov 01; 67(3):310-5. Clarke DF, Acosta EP, Rizk ML, Bryson YJ, Spector SA, Mofenson LM, Handelsman E, Teppler H, Welebob C, Persaud D, Cababasay MP, Wang J, Mirochnick M. PMID: 25162819.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    43. Interleukin 23 produced by myeloid dendritic cells contributes to T-cell dysfunction in HIV type 1 infection by inducing SOCS1 expression. J Infect Dis. 2015 Mar 01; 211(5):755-68. Garg A, Rawat P, Spector SA. PMID: 25234720.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    44. Associations of host genetic variants on CD4? lymphocyte count and plasma HIV-1 RNA in antiretroviral naïve children. Pediatr Infect Dis J. 2014 Sep; 33(9):946-52. Qin M, Brummel S, Singh KK, Fenton T, Spector SA. PMID: 24797997.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. Control lymphocyte subsets: can one country's values serve for another's? J Allergy Clin Immunol. 2014 Sep; 134(3):759-761.e8. Mandala WL, Ananworanich J, Apornpong T, Kerr SJ, MacLennan JM, Hanson C, Jaimulwong T, Gondwe EN, Rosenblatt HM, Bunupuradah T, Molyneux ME, Spector SA, Pancharoen C, Gelman RS, MacLennan CA, Shearer WT. PMID: 25171870.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    46. In-Country Migration and Risk Factors for HIV Acquisition among Pregnant Women in Tijuana, Mexico. J Int Assoc Provid AIDS Care. 2016 05; 15(3):228-31. Viani RM, Araneta MR, Spector SA. PMID: 24935694.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. Trends in hospitalizations among children and young adults with perinatally acquired HIV. Pediatr Infect Dis J. 2014 May; 33(5):488-94. Berry SA, Gebo KA, Rutstein RM, Althoff KN, Korthuis PT, Gaur AH, Spector SA, Warford R, Yehia BR, Agwu AL. PMID: 24378943.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    48. Pediatric treatment 2.0: ensuring a holistic response to caring for HIV-exposed and infected children. AIDS. 2013 Nov; 27 Suppl 2:S215-24. Essajee SM, Arpadi SM, Dziuban EJ, Gonzalez-Montero R, Heidari S, Jamieson DG, Kellerman SE, Koumans E, Ojoo A, Rivadeneira E, Spector SA, Walkowiak H. PMID: 24361631.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Vitamin D-related host genetic variants alter HIV disease progression in children. Pediatr Infect Dis J. 2013 Nov; 32(11):1230-6. Moodley A, Qin M, Singh KK, Spector SA. PMID: 23736144.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    50. Pharmacokinetics, safety, and 48-week efficacy of oral raltegravir in HIV-1-infected children aged 2 through 18 years. Clin Infect Dis. 2014 Feb; 58(3):413-22. Nachman S, Zheng N, Acosta EP, Teppler H, Homony B, Graham B, Fenton T, Xu X, Wenning L, Spector SA, Frenkel LM, Alvero C, Worrell C, Handelsman E, Wiznia A. PMID: 24145879.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsCTClinical Trials
    51. HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity. J Infect Dis. 2014 Feb 01; 209(3):441-51. Garg A, Spector SA. PMID: 23999600.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    52. Immunogenicity of Licensed Influenza A (H1N1) 2009 Monovalent Vaccines in HIV-Infected Children and Youth. J Pediatric Infect Dis Soc. 2013 Dec; 2(4):352-60. Pass RF, Nachman S, Flynn PM, Muresan P, Fenton T, Cunningham CK, Borkowsky W, McAuley JB, Spector SA, Petzold E, Levy W, Siberry GK, Handelsman E, Utech LJ, Weinberg A. PMID: 24363932.
      View in: PubMed   Mentions: 2     Fields:    
    53. Inhibition of human immunodeficiency virus type-1 through autophagy. Curr Opin Microbiol. 2013 Jun; 16(3):349-54. Campbell GR, Spector SA. PMID: 23747172.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    54. Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion. AIDS. 2013 Jun 01; 27(9):1397-401. Campbell GR, Pallack ZT, Spector SA. PMID: 23435299.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    55. Conformity of pediatric/adolescent HIV clinics to the patient-centered medical home care model. AIDS Patient Care STDS. 2013 May; 27(5):272-9. Yehia BR, Agwu AL, Schranz A, Korthuis PT, Gaur AH, Rutstein R, Sharp V, Spector SA, Berry SA, Gebo KA. PMID: 23651104.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    56. Genetic variants in toll-like receptor 2 (TLR2), TLR4, TLR9, and FC? receptor II are associated with antibody response to quadrivalent meningococcal conjugate vaccine in HIV-infected youth. Clin Vaccine Immunol. 2013 Jun; 20(6):900-6. Spector SA, Qin M, Lujan-Zilbermann J, Singh KK, Warshaw MG, Williams PL, Jean-Philippe P, Fenton T, Siberry GK. PMID: 23595505.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    57. Genetic variants in the host restriction factor APOBEC3G are associated with HIV-1-related disease progression and central nervous system impairment in children. J Acquir Immune Defic Syndr. 2013 Feb 01; 62(2):197-203. Singh KK, Wang Y, Gray KP, Farhad M, Brummel S, Fenton T, Trout R, Spector SA. PMID: 23138837.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    58. High proportions of regulatory B and T cells are associated with decreased cellular responses to pH1N1 influenza vaccine in HIV-infected children and youth (IMPAACT P1088). Hum Vaccin Immunother. 2013 May; 9(5):957-68. Weinberg A, Muresan P, Fenton T, Richardson K, Dominguez T, Bloom A, Petzold E, Anthony P, Cunningham CK, Spector SA, Nachman S, Siberry GK, Handelsman E, Flynn PM. PMID: 23370281.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    59. Identification of a candidate therapeutic autophagy-inducing peptide. Nature. 2013 Feb 14; 494(7436):201-6. Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D, Huerta C, Virgin HW, Helms JB, Eerland R, Tooze SA, Xavier R, Lenschow DJ, Yamamoto A, King D, Lichtarge O, Grishin NV, Spector SA, Kaloyanova DV, Levine B. PMID: 23364696.
      View in: PubMed   Mentions: 207     Fields:    Translation:HumansAnimalsCells
    60. Parallel rapid HIV testing in pregnant women at Tijuana General Hospital, Baja California, Mexico. AIDS Res Hum Retroviruses. 2013 Mar; 29(3):429-34. Viani RM, Araneta MR, Spector SA. PMID: 23050550.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    61. Toll-like receptor 8 ligands activate a vitamin D mediated autophagic response that inhibits human immunodeficiency virus type 1. PLoS Pathog. 2012; 8(11):e1003017. Campbell GR, Spector SA. PMID: 23166493.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCellsCTClinical Trials
    62. Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1. Autophagy. 2012 Oct; 8(10):1523-5. Campbell GR, Spector SA. PMID: 22892387.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    63. Nevirapine exposure with WHO pediatric weight band dosing: enhanced therapeutic concentrations predicted based on extensive international pharmacokinetic experience. Antimicrob Agents Chemother. 2012 Oct; 56(10):5374-80. Nikanjam M, Kabamba D, Cressey TR, Burger D, Aweeka FT, Acosta EP, Spector SA, Capparelli EV. PMID: 22869579.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    64. The influence of HLA on HIV-associated neurocognitive impairment in Anhui, China. PLoS One. 2012; 7(5):e32303. Schrier RD, Gupta S, Riggs P, Cysique LA, Letendre S, Jin H, Spector SA, Singh KK, Wolfson T, Wu Z, Hong KX, Yu X, Shi C, Heaton RK. PMID: 22693541.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    65. Immunogenicity and safety of 1 vs 2 doses of quadrivalent meningococcal conjugate vaccine in youth infected with human immunodeficiency virus. J Pediatr. 2012 Oct; 161(4):676-81.e2. Lujan-Zilbermann J, Warshaw MG, Williams PL, Spector SA, Decker MD, Abzug MJ, Heckman B, Manzella A, Kabat B, Jean-Philippe P, Nachman S, Siberry GK. PMID: 22622049.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    66. Safety and immunogenicity of 2009 pandemic H1N1 influenza vaccination in perinatally HIV-1-infected children, adolescents, and young adults. J Infect Dis. 2012 Aug 01; 206(3):421-30. Flynn PM, Nachman S, Muresan P, Fenton T, Spector SA, Cunningham CK, Pass R, Yogev R, Burchett S, Heckman B, Bloom A, Utech LJ, Anthony P, Petzold E, Levy W, Siberry GK, Ebiasah R, Miller J, Handelsman E, Weinberg A. PMID: 22615311.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    67. Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy. PLoS Pathog. 2012; 8(5):e1002689. Campbell GR, Spector SA. PMID: 22589721.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    68. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. PMID: 22966490.
      View in: PubMed   Mentions: 1430     Fields:    Translation:HumansAnimals
    69. Production of interferon a by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy. J Infect Dis. 2012 Apr 15; 205(8):1258-67. Zhou D, Kang KH, Spector SA. PMID: 22396599.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    70. Antiretroviral therapy does not block the secretion of the human immunodeficiency virus tat protein. Infect Disord Drug Targets. 2012 Feb; 12(1):81-6. Mediouni S, Darque A, Baillat G, Ravaux I, Dhiver C, Tissot-Dupont H, Mokhtari M, Moreau H, Tamalet C, Brunet C, Paul P, Dignat-George F, Stein A, Brouqui P, Spector SA, Campbell GR, Loret EP. PMID: 22280310.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    71. Safety and immunogenicity of quadrivalent meningococcal conjugate vaccine in 2- to 10-year-old human immunodeficiency virus-infected children. Pediatr Infect Dis J. 2012 Jan; 31(1):47-52. Siberry GK, Warshaw MG, Williams PL, Spector SA, Decker MD, Jean-Philippe P, Yogev R, Heckman BE, Manzella A, Roa J, Nachman S, Lujan-Zilbermann J. PMID: 21987006.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    72. Metabolic abnormalities and viral replication are associated with biomarkers of vascular dysfunction in HIV-infected children. HIV Med. 2012 May; 13(5):264-75. Miller TI, Borkowsky W, DiMeglio LA, Dooley L, Geffner ME, Hazra R, McFarland EJ, Mendez AJ, Patel K, Siberry GK, Van Dyke RB, Worrell CJ, Jacobson DL, Shearer W, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Patton D, Burchett S, Karthas N, Kammerer B, Yogev R, Malee K, Hunter S, Cagwin E, Wiznia A, Burey M, Nozyce M, Chen J, Gobs E, Grant M, Knapp K, Allison K, Garvie P, Acevedo-Flores M, Rios H, Olivera V, Silio M, Borne C, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Barr E, Chambers C, Watson D, Messenger N, Belanger R, Dieudonne A, Bettica L, Adubato S, Scott G, Himic L, Willen E. PMID: 22136114.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    73. Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care site. J Adolesc Health. 2012 May; 50(5):471-7. Agwu AL, Siberry GK, Ellen J, Fleishman JA, Rutstein R, Gaur AH, Korthuis PT, Warford R, Spector SA, Gebo KA. PMID: 22525110.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    74. CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruption. J Acquir Immune Defic Syndr. 2011 Jul 01; 57(3):223-9. Siberry GK, Patel K, Van Dyke RB, Hazra R, Burchett SK, Spector SA, Paul ME, Read JS, Wiznia A, Seage GR. PMID: 21423022.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    75. Clinical Outcomes and Hospitalizations among Children Perinatally Infected with HIV-1 in Baja California, Mexico. J Int Assoc Physicians AIDS Care (Chic). 2011 Jul-Aug; 10(4):223-8. Viani RM, Araneta MR, Lopez G, Chacón-Cruz E, Spector SA. PMID: 21690301.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    76. Antiretroviral treatment of US children with perinatally acquired HIV infection: temporal changes in therapy between 1991 and 2009 and predictors of immunologic and virologic outcomes. J Acquir Immune Defic Syndr. 2011 Jun 01; 57(2):165-73. Van Dyke RB, Patel K, Siberry GK, Burchett SK, Spector SA, Chernoff MC, Read JS, Mofenson LM, Seage GR. PMID: 21407086.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    77. Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis. J Infect Dis. 2011 Jun 01; 203(11):1647-57. Zhou D, Masliah E, Spector SA. PMID: 21592995.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    78. HLA alleles are associated with altered risk for disease progression and central nervous system impairment of HIV-infected children. J Acquir Immune Defic Syndr. 2011 May 01; 57(1):32-9. Singh KK, Gray PK, Wang Y, Fenton T, Trout RN, Spector SA. PMID: 21283014.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    79. Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection. J Biol Chem. 2011 May 27; 286(21):18890-902. Campbell GR, Spector SA. PMID: 21454634.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    80. Incidence of and risk factors for community acquired pneumonia in US HIV-infected children, 2000-2005. AIDS. 2011 Mar 13; 25(5):717-20. Steenhoff AP, Josephs JS, Rutstein RM, Gebo KA, Siberry GK, Gaur AH, Warford R, Korthuis PT, Spector SA, Shah SS. PMID: 21252630.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    81. Vitamin D and HIV: letting the sun shine in. Top Antivir Med. 2011 Feb-Mar; 19(1):6-10. Spector SA. PMID: 21852710.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    82. Psychological factors, beliefs about medication, and adherence of youth with human immunodeficiency virus in a multisite directly observed therapy pilot study. J Adolesc Health. 2011 Jun; 48(6):637-40. Garvie PA, Flynn PM, Belzer M, Britto P, Hu C, Graham B, Neely M, McSherry GD, Spector SA, Gaur AH. PMID: 21575827.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    83. Differential induction of rat neuronal excitotoxic cell death by human immunodeficiency virus type 1 clade B and C tat proteins. AIDS Res Hum Retroviruses. 2011 Jun; 27(6):647-54. Campbell GR, Watkins JD, Loret EP, Spector SA. PMID: 20977378.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    84. Substance use in HIV-Infected women during pregnancy: self-report versus meconium analysis. AIDS Behav. 2010 Dec; 14(6):1269-78. Tassiopoulos K, Read JS, Brogly S, Rich K, Lester B, Spector SA, Yogev R, Seage GR. PMID: 20532607.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansPHPublic Health
    85. Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy. Pediatr Infect Dis J. 2010 Dec; 29(12):1118-22. Cervia JS, Chantry CJ, Hughes MD, Alvero C, Meyer WA, Hodge J, Borum P, Moye J, Spector SA. PMID: 20631646.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    86. Directly observed therapy (DOT) for nonadherent HIV-infected youth: lessons learned, challenges ahead. AIDS Res Hum Retroviruses. 2010 Sep; 26(9):947-53. Gaur AH, Belzer M, Britto P, Garvie PA, Hu C, Graham B, Neely M, McSherry G, Spector SA, Flynn PM. PMID: 20707731.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    87. CYP2C19 genetic variants affect nelfinavir pharmacokinetics and virologic response in HIV-1-infected children receiving highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2010 Jul; 54(3):285-9. Saitoh A, Capparelli E, Aweeka F, Sarles E, Singh KK, Kovacs A, Burchett SK, Wiznia A, Nachman S, Fenton T, Spector SA. PMID: 19890215.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    88. APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors. AIDS. 2010 Jun 19; 24(10):1471-9. Spector SA, Singh KK, Gupta S, Cystique LA, Jin H, Letendre S, Schrier R, Wu Z, Hong KX, Yu X, Shi C, Heaton RK. PMID: 20442634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    89. Phase I/II, open-label trial of safety and immunogenicity of meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine in human immunodeficiency virus-infected adolescents. Pediatr Infect Dis J. 2010 May; 29(5):391-6. Siberry GK, Williams PL, Lujan-Zilbermann J, Warshaw MG, Spector SA, Decker MD, Heckman BE, Demske EF, Read JS, Jean-Philippe P, Kabat W, Nachman S. PMID: 20431379.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    90. Differential induction of interleukin-10 in monocytes by HIV-1 clade B and clade C Tat proteins. J Biol Chem. 2010 Jun 11; 285(24):18319-25. Wong JK, Campbell GR, Spector SA. PMID: 20378550.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    91. Mother-to-child HIV transmission in a cohort of pregnant women diagnosed by rapid HIV testing at Tijuana General Hospital, Baja California, Mexico. J Int Assoc Physicians AIDS Care (Chic). 2010 Mar-Apr; 9(2):82-6. Viani RM, Ruiz-Calderon J, Lopez G, Chacón-Cruz E, Spector SA. PMID: 20335496.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    92. Human metapneumovirus associated with central nervous system infection in children. Pediatr Infect Dis J. 2009 Dec; 28(12):1057-60. Arnold JC, Singh KK, Milder E, Spector SA, Sawyer MH, Gavali S, Glaser C. PMID: 19755929.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    93. HIV-1 clade B Tat, but not clade C Tat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells. J Biol Chem. 2010 Jan 15; 285(3):1681-91. Campbell GR, Loret EP, Spector SA. PMID: 19917610.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    94. Vitamin D earns more than a passing grade. J Infect Dis. 2009 Oct 01; 200(7):1015-7. Spector SA. PMID: 19673648.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    95. Host genetic determinants of human immunodeficiency virus infection and disease progression in children. Pediatr Res. 2009 May; 65(5 Pt 2):55R-63R. Singh KK, Spector SA. PMID: 19190524.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    96. Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals. J Acquir Immune Defic Syndr. 2008 Nov 01; 49(3):259-65. Singh KK, Hughes MD, Chen J, Phiri K, Rousseau C, Kuhn L, Coutsoudis A, Jackson JB, Guay LA, Musoke P, Mmiro F, Semba RD, Spector SA. PMID: 18845960.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    97. CCL2 increases X4-tropic HIV-1 entry into resting CD4+ T cells. J Biol Chem. 2008 Nov 07; 283(45):30745-53. Campbell GR, Spector SA. PMID: 18784079.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    98. Analyses of HIV-1 drug-resistance profiles among infected adolescents experiencing delayed antiretroviral treatment switch after initial nonsuppressive highly active antiretroviral therapy. AIDS Patient Care STDS. 2008 Jul; 22(7):545-52. Agwu A, Lindsey JC, Ferguson K, Zhang H, Spector S, Rudy BJ, Ray SC, Douglas SD, Flynn PM, Persaud D. PMID: 18479228.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    99. An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children. J Allergy Clin Immunol. 2008 Jul; 122(1):173-80, 180.e1-2. Singh KK, Lieser A, Ruan PK, Fenton T, Spector SA. PMID: 18602571.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    100. Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells. Antimicrob Agents Chemother. 2008 Aug; 52(8):2825-30. Saitoh A, Haas RH, Naviaux RK, Salva NG, Wong JK, Spector SA. PMID: 18541728.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    101. Autophagy: an overlooked mechanism of HIV-1 pathogenesis and neuroAIDS? Autophagy. 2008 Jul; 4(5):704-6. Spector SA, Zhou D. PMID: 18424919.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    102. Human immunodeficiency virus type-1 infection inhibits autophagy. AIDS. 2008 Mar 30; 22(6):695-9. Zhou D, Spector SA. PMID: 18356598.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    103. Clinical outcomes after an unstructured treatment interruption in children and adolescents with perinatally acquired HIV infection. Pediatrics. 2008 Mar; 121(3):e513-21. Saitoh A, Foca M, Viani RM, Heffernan-Vacca S, Vaida F, Lujan-Zilbermann J, Emmanuel PJ, Deville JG, Spector SA. PMID: 18310171.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    104. Undiagnosed respiratory viruses in children. Pediatrics. 2008 Mar; 121(3):e631-7. Arnold JC, Singh KK, Spector SA, Sawyer MH. PMID: 18310182.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    105. Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors. Futur HIV Ther. 2008 Jan 01; 2(1):69-81. Saitoh A, Spector SA. PMID: 21197270.
      View in: PubMed   Mentions:
    106. CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS. 2007 Oct 18; 21(16):2191-9. Saitoh A, Sarles E, Capparelli E, Aweeka F, Kovacs A, Burchett SK, Wiznia A, Nachman S, Fenton T, Spector SA. PMID: 18090046.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    107. Long-term observation of adolescents initiating HAART therapy: three-year follow-up. AIDS Res Hum Retroviruses. 2007 Oct; 23(10):1208-14. Flynn PM, Rudy BJ, Lindsey JC, Douglas SD, Lathey J, Spector SA, Martinez J, Silio M, Belzer M, Friedman L, D'Angelo L, Smith E, Hodge J, Hughes MD. PMID: 17961106.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    108. Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction. Blood. 2008 Jan 01; 111(1):175-82. Bolovan-Fritts CA, Spector SA. PMID: 17895402.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    109. Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy. Antimicrob Agents Chemother. 2007 Dec; 51(12):4236-42. Saitoh A, Fenton T, Alvero C, Fletcher CV, Spector SA. PMID: 17893156.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    110. Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021. Pediatrics. 2007 Aug; 120(2):e416-23. McKinney RE, Rodman J, Hu C, Britto P, Hughes M, Smith ME, Serchuck LK, Kraimer J, Ortiz AA, Flynn P, Yogev R, Spector S, Draper L, Tran P, Scites M, Dickover R, Weinberg A, Cunningham C, Abrams E, Blum MR, Chittick GE, Reynolds L, Rathore M. PMID: 17646352.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsCTClinical Trials
    111. Efavirenz pharmacokinetics in HIV-1-infected children are associated with CYP2B6-G516T polymorphism. J Acquir Immune Defic Syndr. 2007 Jul 01; 45(3):280-5. Saitoh A, Fletcher CV, Brundage R, Alvero C, Fenton T, Hsia K, Spector SA. PMID: 17356468.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCellsCTClinical Trials
    112. High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage. Blood. 2007 Sep 15; 110(6):1857-63. Bolovan-Fritts CA, Trout RN, Spector SA. PMID: 17519388.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    113. Human immunodeficiency virus type 1 subtype C Tat fails to induce intracellular calcium flux and induces reduced tumor necrosis factor production from monocytes. J Virol. 2007 Jun; 81(11):5919-28. Campbell GR, Watkins JD, Singh KK, Loret EP, Spector SA. PMID: 17376903.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    114. Prevalence of primary HIV-1 drug resistance among recently infected adolescents: a multicenter adolescent medicine trials network for HIV/AIDS interventions study. J Infect Dis. 2006 Dec 01; 194(11):1505-9. Viani RM, Peralta L, Aldrovandi G, Kapogiannis BG, Mitchell R, Spector SA, Lie YS, Weidler JM, Bates MP, Liu N, Wilson CM. PMID: 17083034.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    115. Mitochondrial dysfunction: prevention of HIV-1 mother-to-infant transmission outweighs fear. AIDS. 2006 Aug 22; 20(13):1777-8. Spector SA, Saitoh A. PMID: 16931943.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    116. Human bocavirus: prevalence and clinical spectrum at a children's hospital. Clin Infect Dis. 2006 Aug 01; 43(3):283-8. Arnold JC, Singh KK, Spector SA, Sawyer MH. PMID: 16804840.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCellsPHPublic Health
    117. Association of CD4+ T-lymphocyte counts and new thymic emigrants in HIV-infected children during successful highly active antiretroviral therapy. J Allergy Clin Immunol. 2006 Apr; 117(4):909-15. Saitoh A, Singh KK, Sandall S, Powell CA, Fenton T, Fletcher CV, Hsia K, Spector SA. PMID: 16630951.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    118. Impact of pregnancy on abacavir pharmacokinetics. AIDS. 2006 Feb 28; 20(4):553-60. Best BM, Mirochnick M, Capparelli EV, Stek A, Burchett SK, Holland DT, Read JS, Smith E, Hu C, Spector SA, Connor JD. PMID: 16470119.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    119. Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States. AIDS. 2006 Feb 14; 20(3):475-8. Singh KK, Hughes MD, Chen J, Spector SA. PMID: 16439891.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    120. Perinatal HIV counseling and rapid testing in Tijuana, Baja California, Mexico: seroprevalence and correlates of HIV infection. J Acquir Immune Defic Syndr. 2006 Jan 01; 41(1):87-92. Viani RM, Araneta MR, Ruiz-Calderon J, Hubbard P, Lopez G, Chacón-Cruz E, Spector SA. PMID: 16340479.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    121. The C terminus of HIV-1 Tat modulates the extent of CD178-mediated apoptosis of T cells. J Biol Chem. 2005 Nov 18; 280(46):38376-82. Campbell GR, Watkins JD, Esquieu D, Pasquier E, Loret EP, Spector SA. PMID: 16155003.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    122. Hospital and outpatient health services utilization among HIV-infected children in care 2000-2001. Med Care. 2005 Sep; 43(9 Suppl):III31-9. Rutstein RM, Gebo KA, Siberry GK, Flynn PM, Spector SA, Sharp VL, Fleishman JA. PMID: 16116307.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    123. Immunologic function and virologic suppression among children with perinatally acquired HIV Infection on highly active antiretroviral therapy. Med Care. 2005 Sep; 43(9 Suppl):III15-22. Rutstein RM, Gebo KA, Flynn PM, Fleishman JA, Sharp VL, Siberry GK, Spector SA. PMID: 16116305.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsCTClinical Trials
    124. Myelomeningocele in an infant with intrauterine exposure to efavirenz. J Perinatol. 2005 Aug; 25(8):555-6. Saitoh A, Hull AD, Franklin P, Spector SA. PMID: 16047034.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    125. Migration and risk factors for HIV acquisition in pregnant women in Baja California, Mexico. MedGenMed. 2005 Jun 22; 7(2):69. Viani RM, Araneta MR, Ruiz-Calderon J, Hubbard P, Lopez G, Chacón-Cruz E, Spector SA. PMID: 16369447.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    126. Genetic polymorphisms in CX3CR1 predict HIV-1 disease progression in children independently of CD4+ lymphocyte count and HIV-1 RNA load. J Infect Dis. 2005 Jun 01; 191(11):1971-80. Singh KK, Hughes MD, Chen J, Spector SA. PMID: 15871132.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    127. An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. AIDS. 2005 Mar 04; 19(4):371-80. Saitoh A, Singh KK, Powell CA, Fenton T, Fletcher CV, Brundage R, Starr S, Spector SA. PMID: 15750390.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    128. The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid. J Neuroimmunol. 2004 Dec; 157(1-2):193-6. Letendre S, Marquie-Beck J, Singh KK, de Almeida S, Zimmerman J, Spector SA, Grant I, Ellis R. PMID: 15579297.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    129. Human cytomegalovirus-specific CD4+-T-cell cytokine response induces fractalkine in endothelial cells. J Virol. 2004 Dec; 78(23):13173-81. Bolovan-Fritts CA, Trout RN, Spector SA. PMID: 15542669.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    130. CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults. J Neuroimmunol. 2004 Dec; 157(1-2):185-92. Singh KK, Ellis RJ, Marquie-Beck J, Letendre S, Heaton RK, Grant I, Spector SA. PMID: 15579296.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    131. Treatment of infants coinfected with HIV-1 and cytomegalovirus with combination antiretrovirals and ganciclovir. J Allergy Clin Immunol. 2004 Oct; 114(4):983-5. Saitoh A, Viani RM, Schrier RD, Spector SA. PMID: 15480350.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    132. Decrease in hospitalization and mortality rates among children with perinatally acquired HIV type 1 infection receiving highly active antiretroviral therapy. Clin Infect Dis. 2004 Sep 01; 39(5):725-31. Viani RM, Araneta MR, Deville JG, Spector SA. PMID: 15356789.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    133. Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy. J Infect Dis. 2004 Jul 15; 190(2):271-9. Flynn PM, Rudy BJ, Douglas SD, Lathey J, Spector SA, Martinez J, Silio M, Belzer M, Friedman L, D'Angelo L, McNamara J, Hodge J, Hughes MD, Lindsey JC. PMID: 15216461.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCellsCTClinical Trials
    134. Longitudinal analysis of lymphocyte ratios and HIV-1 intracellular DNA levels in children. J Infect Dis. 2004 Apr 01; 189(7):1216-20. Saitoh A, Powell CA, Fenton T, Douglas SD, Starr SE, Fletcher CV, Spector SA. PMID: 15031790.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    135. Impaired lymphoid chemokine-mediated migration due to a block on the chemokine receptor switch in human cytomegalovirus-infected dendritic cells. J Virol. 2004 Mar; 78(6):3046-54. Moutaftsi M, Brennan P, Spector SA, Tabi Z. PMID: 14990723.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    136. Intrapatient variability of efavirenz concentrations as a predictor of virologic response to antiretroviral therapy. Antimicrob Agents Chemother. 2004 Mar; 48(3):979-84. Brundage RC, Yong FH, Fenton T, Spector SA, Starr SE, Fletcher CV. PMID: 14982792.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    137. Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States. J Acquir Immune Defic Syndr. 2004 Mar 01; 35(3):309-13. Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA. PMID: 15076247.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    138. Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior. J Infect Dis. 2004 Feb 15; 189(4):593-601. Wu H, Lathey J, Ruan P, Douglas SD, Spector SA, Lindsey J, Hughes MD, Rudy BJ, Flynn PM. PMID: 14767811.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    139. Lack of protective effects of interleukin-4 -589-C/T polymorphism against HIV-1-related disease progression and central nervous system impairment, in children. J Infect Dis. 2004 Feb 15; 189(4):587-92. Singh KK, Hughes MD, Chen J, Spector SA. PMID: 14767810.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    140. Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents. Lancet. 2003 Dec 20; 362(9401):2045-51. Soh CH, Oleske JM, Brady MT, Spector SA, Borkowsky W, Burchett SK, Foca MD, Handelsman E, Jiménez E, Dankner WM, Hughes MD. PMID: 14697803.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    141. Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection. J Infect Dis. 2003 Nov 15; 188(10):1461-72. Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA. PMID: 14624371.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    142. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol. 2003 Nov; 112(5):973-80. Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara DW, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, Graham BL, Spector SA. PMID: 14610491.
      View in: PubMed   Mentions: 217     Fields:    Translation:HumansCells
    143. Comparison of molecular tests for detection and quantification of cell-associated cytomegalovirus DNA. J Clin Microbiol. 2003 Aug; 41(8):3509-13. Caliendo AM, Yen-Lieberman B, Baptista J, Andersen J, Crumpacker C, Schuurman R, Spector SA, Bremer J, Lurain NS. PMID: 12904347.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    144. HIV prevalence during pregnancy in Tijuana, Baja California, Mexico. AIDS. 2003 May 02; 17(7):1113-4. Viani RM, Calderon JR, Van Pratt C, Lopez G, Spector SA. PMID: 12700474.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    145. Population pharmacokinetics and pharmacodynamics of zidovudine in HIV-infected infants and children. J Clin Pharmacol. 2003 Feb; 43(2):133-40. Capparelli EV, Englund JA, Connor JD, Spector SA, McKinney RE, Palumbo P, Baker CJ. PMID: 12616665.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    146. HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells. J Hematother Stem Cell Res. 2002 Oct; 11(5):829-47. Williams MA, Trout R, Spector SA. PMID: 12427289.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    147. Protease inhibitors and decreased birth weight in HIV-infected pregnant women with impaired glucose tolerance. J Perinatol. 2002 Jul-Aug; 22(5):370-3. Chmait R, Franklin P, Spector SA, Hull AD. PMID: 12082471.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    148. Efavirenz liquid formulation in human immunodeficiency virus-infected children. Pediatr Infect Dis J. 2002 Jul; 21(7):659-63. Starr SE, Fletcher CV, Spector SA, Brundage RC, Yong FH, Douglas SD, Flynn PM, Kline MW. PMID: 12237599.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsCTClinical Trials
    149. Detection of replication-competent human immunodeficiency virus type 1 (HIV-1) in cultures from patients with levels of HIV-1 RNA in plasma suppressed to less than 500 or 50 copies per milliliter. J Clin Microbiol. 2002 Jun; 40(6):2089-94. Demeter LM, Bosch RJ, Coombs RW, Fiscus S, Bremer J, Johnson VA, Erice A, Jackson JB, Spector SA, Squires KM, Fischl MA, Hughes MD, Hammer SM. PMID: 12037070.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    150. Progression to neuropsychological impairment in human immunodeficiency virus infection predicted by elevated cerebrospinal fluid levels of human immunodeficiency virus RNA. Arch Neurol. 2002 Jun; 59(6):923-8. Ellis RJ, Moore DJ, Childers ME, Letendre S, McCutchan JA, Wolfson T, Spector SA, Hsia K, Heaton RK, Grant I. PMID: 12056927.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    151. Persistence of human immunodeficiency virus (HIV) type 1 DNA in peripheral blood despite prolonged suppression of plasma HIV-1 RNA in children. J Infect Dis. 2002 May 15; 185(10):1409-16. Saitoh A, Hsia K, Fenton T, Powell CA, Christopherson C, Fletcher CV, Starr SE, Spector SA. PMID: 11992275.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    152. Mother-to-infant transmission of HIV-1: the placenta fights back. J Clin Invest. 2001 Feb; 107(3):267-9. Spector SA. PMID: 11160148.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    153. Factors impacting on drug choices. Issues for developing countries. Ann N Y Acad Sci. 2000 Nov; 918:346-50. Spector SA. PMID: 11131721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    154. Patterns of plasma human immunodeficiency virus type 1 RNA response to highly active antiretroviral therapy in infected children. J Infect Dis. 2000 Dec; 182(6):1769-73. Spector SA, Hsia K, Yong FH, Cabral S, Fenton T, Fletcher CV, McNamara J, Mofenson LM, Starr SE. PMID: 11069252.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    155. Cytomegalovirus (CMV) DNA load is an independent predictor of CMV disease and survival in advanced AIDS. J Virol. 1999 Aug; 73(8):7027-30. Spector SA, Hsia K, Crager M, Pilcher M, Cabral S, Stempien MJ. PMID: 10400803.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    156. Plasma cytomegalovirus (CMV) DNA load predicts CMV disease and survival in AIDS patients. J Clin Invest. 1998 Jan 15; 101(2):497-502. Spector SA, Wong R, Hsia K, Pilcher M, Stempien MJ. PMID: 9435323.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCellsCTClinical Trials
    Stephen's Networks
    Concepts (615)
    Derived automatically from this person's publications.
    _
    Co-Authors (69)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _