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Ronald Ellis

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address200 W. Arbor Drive #8231
San Diego CA 92103
Phone619-543-5079
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    Collapse Overview 
    Collapse Overview
    Dr. Ellis’s clinical work and research are focused on the neurological manifestations of HIV infection and their pathogenesis and treatment, particularly dementia, neurocognitive disorders and sensory polyneuropathy. He is Associate Director of the NIMH-funded P03 HIV Neurobehavioral Research Programs (HNRP) and PI of its Neuromedical Core, which is comprised of two interacting subunits, a Clinical Research Support Unit (CRSU) and a Laboratory, Pharmacology and Biomarker Unit (LPBU). He also serves as an investigator in the multicenter CNS HIV AntiRetroviral Therapy Effects Research (CHARTER) study and the Translational Methamphetamine AIDS Research Center (TMARC). TMARC comprises an integrated program of human clinical, neuroimaging, laboratory and animal model investigations being conducted at UCSD, The Sanford-Burnham Institute, and the Scripps Institute.


    Collapse Research 
    Collapse Research Activities and Funding
    Effect of Cannabis Administration and Endocannabinoids on HIV Neuropathic Pain
    NIH/NIDA R01DA043430Feb 1, 2017 - Dec 31, 2020
    Role: Principal Investigator
    Phase II trial of tesamorelin for cognition in aging HIV-infected persons
    NIH/NIA R01AG048650Sep 30, 2015 - May 31, 2020
    Role: Principal Investigator
    Building research capacity in aging HIV-infected persons
    NIH/NIA R03AG044910Sep 30, 2013 - Jul 31, 2015
    Role: Principal Investigator
    Intrahost HIV population dynamics in CNS and other tissues
    NIH/NIMH R01MH101012May 1, 2013 - Jan 31, 2016
    Role: Principal Investigator
    HIV Clade on Cognitive and Neurological Disorders Brazil
    NIH/NIMH R21MH076651Jan 25, 2006 - Dec 31, 2009
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH/NIMH P30MH062512Apr 24, 2001 - Feb 28, 2021
    Role: Co-Investigator
    NEUROAIDS: EFFECTS OF METHAMPHETAMINE AND HCV
    NIH/NIDA P01DA012065Jul 1, 1999 - Apr 30, 2011
    Role: Co-Investigator
    HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART
    NIH/NIMH R01MH058076Sep 30, 1997 - Jul 31, 2012
    Role: Principal Investigator
    CEREBRAL LATERALITY IN AGING ALCOHOLICS
    NIH/NIAAA F31AA005260Mar 1, 1987
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

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    Collapse Clinical Trials
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. de Almeida SM, Oliveira MF, Chaillon A, Rotta I, Ribeiro CE, de Pereira AP, Smith D, Letendre S, Ellis RJ. Transient and asymptomatic meningitis in human immunodeficiency virus-1 subtype C: a case study of genetic compartmentalization and biomarker dynamics. J Neurovirol. 2018 Sep 07. PMID: 30194587.
      View in: PubMed
    2. Chow FC, Makanjuola A, Wu K, Berzins B, Kim KA, Ogunniyi A, Ellis R, Robertson K, Tassiopolous K, Taiwo B. Physical activity is associated with lower odds of cognitive impairment in women but not men living with HIV infection. J Infect Dis. 2018 Aug 18. PMID: 30137500.
      View in: PubMed
    3. Basova L, Najera JA, Bortell N, Wang D, Moya R, Lindsey A, Semenova S, Ellis RJ, Marcondes MCG. Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection. PLoS One. 2018; 13(6):e0199861. PMID: 29944719.
      View in: PubMed
    4. Soontornniyomkij V, Umlauf A, Soontornniyomkij B, Gouaux B, Ellis RJ, Levine AJ, Moore DJ, Letendre SL. Association of antiretroviral therapy with brain aging changes among HIV-infected adults. AIDS. 2018 Jun 14. PMID: 29912063.
      View in: PubMed
    5. Oppenheim H, Paolillo EW, Moore RC, Ellis RJ, Letendre SL, Jeste DV, Grant I, Moore DJ. Neurocognitive functioning predicts frailty index in HIV. Neurology. 2018 Jun 06. PMID: 29875216.
      View in: PubMed
    6. de Almeida SM, Tang B, Ribeiro CE, Rotta I, Vaida F, Piovesan M, Batistela Fernandes MS, Letendre S, Potter M, Ellis RJ. Neprilysin in the Cerebrospinal Fluid and Serum of Patients Infected With HIV1-Subtypes C and B. J Acquir Immune Defic Syndr. 2018 Jun 01; 78(2):248-256. PMID: 29481488.
      View in: PubMed
    7. Chow FC, Wilson MR, Wu K, Ellis RJ, Bosch RJ, Linas BP. Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort. AIDS. 2018 Jun 01; 32(9):1125-1135. PMID: 29746317.
      View in: PubMed
    8. Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living with HIV. Clin Infect Dis. 2018 May 18. PMID: 29788039.
      View in: PubMed
    9. McGehrin K, Konersman C, Ellis R. Clinical Reasoning: A 22-year-old postpartum woman with new-onset seizures and headache. Neurology. 2018 May 01; 90(18):e1631-e1635. PMID: 29712815.
      View in: PubMed
    10. Dufour CA, Marquine MJ, Fazeli PL, Umlauf A, Henry BL, Zlatar Z, Montoya JL, Ellis RJ, Grant I, Moore DJ. A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults. AIDS Behav. 2018 May; 22(5):1562-1572. PMID: 27990580.
      View in: PubMed
    11. Mukerji SS, Misra V, Lorenz DR, Uno H, Morgello S, Franklin D, Ellis RJ, Letendre S, Gabuzda D. Impact of Antiretroviral Regimens on CSF Viral Escape in a Prospective Multicohort Study of ART-Experienced HIV-1 Infected Adults in the United States. Clin Infect Dis. 2018 Apr 03. PMID: 29617912.
      View in: PubMed
    12. Anderson AM, Croteau D, Ellis RJ, Rosario D, Potter M, Guillemin GJ, Brew BJ, Woods SP, Letendre SL. HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau. J Neuroimmunol. 2018 Jun 15; 319:13-18. PMID: 29685284.
      View in: PubMed
    13. de Almeida SM, de Pereira AP, Pedroso MLA, Ribeiro CE, Rotta I, Tang B, Umlauf A, Franklin D, Saloner RG, Batista MGR, Letendre S, Heaton RK, Ellis RJ, Cherner M. Neurocognitive impairment with hepatitis C and HIV co-infection in Southern Brazil. J Neurovirol. 2018 Mar 07. PMID: 29516346.
      View in: PubMed
    14. de Almeida SM, Ribeiro CE, Rotta I, Piovesan M, Tang B, Vaida F, Raboni SM, Letendre S, Potter M, Batistela Fernandes MS, Ellis RJ. Biomarkers of neuronal injury and amyloid metabolism in the cerebrospinal fluid of patients infected with HIV-1 subtypes B and C. J Neurovirol. 2018 Feb; 24(1):28-40. PMID: 29063514.
      View in: PubMed
    15. Marquine MJ, Heaton A, Johnson N, Rivera-Mindt M, Cherner M, Bloss C, Hulgan T, Umlauf A, Moore DJ, Fazeli P, Morgello S, Franklin D, Letendre S, Ellis R, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Simpson D, McCutchan JA, Grant I, Heaton RK. Differences in Neurocognitive Impairment Among HIV-Infected Latinos in the United States. J Int Neuropsychol Soc. 2018 Feb; 24(2):163-175. PMID: 28874213.
      View in: PubMed
    16. Yuen T, Brouillette MJ, Fellows LK, Ellis RJ, Letendre S, Heaton R, Mayo N. Personalized Risk Index for Neurocognitive Decline Among People With Well-Controlled HIV Infection. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):48-54. PMID: 28797021.
      View in: PubMed
    17. Coban H, Robertson K, Smurzynski M, Krishnan S, Wu K, Bosch RJ, Collier AC, Ellis RJ. Impact of aging on neurocognitive performance in previously antiretroviral-naive HIV-infected individuals on their first suppressive regimen. AIDS. 2017 Jul 17; 31(11):1565-1571. PMID: 28471765.
      View in: PubMed
    18. Johs NA, Wu K, Tassiopoulos K, Koletar SL, Kalayjian RC, Ellis RJ, Taiwo B, Palella FJ, Erlandson KM. Disability Among Middle-Aged and Older Persons With Human Immunodeficiency Virus Infection. Clin Infect Dis. 2017 Jul 01; 65(1):83-91. PMID: 28369402.
      View in: PubMed
    19. Yek C, Massanella M, Peling T, Lednovich K, Nair SV, Worlock A, Vargas M, Gianella S, Ellis RJ, Strain MC, Busch MP, Nugent CT, Richman DD. Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types. J Clin Microbiol. 2017 Aug; 55(8):2544-2553. PMID: 28592548.
      View in: PubMed
    20. Jia P, Zhao Z, Hulgan T, Bush WS, Samuels DC, Bloss CS, Heaton RK, Ellis RJ, Schork N, Marra CM, Collier AC, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, McCutchan JA, Barnholtz-Sloan JS, Franklin DR, Rosario D, Letendre SL, Grant I, Kallianpur AR. Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):413-426. PMID: 28447399.
      View in: PubMed
    21. Bryant AK, Moore DJ, Burdo TH, Lakritz JR, Gouaux B, Soontornniyomkij V, Achim CL, Masliah E, Grant I, Levine AJ, Ellis RJ. Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection. AIDS. 2017 Apr 24; 31(7):973-979. PMID: 28244955.
      View in: PubMed
    22. Patton SM, Wang Q, Hulgan T, Connor JR, Jia P, Zhao Z, Letendre SL, Ellis RJ, Bush WS, Samuels DC, Franklin DR, Kaur H, Iudicello J, Grant I, Kallianpur AR. Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults. Fluids Barriers CNS. 2017 Apr 21; 14(1):11. PMID: 28427421.
      View in: PubMed
    23. Mehta SR, Pérez-Santiago J, Hulgan T, Day TR, Barnholtz-Sloan J, Gittleman H, Letendre S, Ellis R, Heaton R, Patton S, Suben JD, Franklin D, Rosario D, Clifford DB, Collier AC, Marra CM, Gelman BB, McArthur J, McCutchan A, Morgello S, Simpson D, Connor J, Grant I, Kallianpur A. Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment. J Neuroinflammation. 2017 Mar 31; 14(1):72. PMID: 28359324.
      View in: PubMed
    24. Montoya JL, Iudicello J, Oppenheim HA, Fazeli PL, Potter M, Ma Q, Mills PJ, Ellis RJ, Grant I, Letendre SL, Moore DJ. Coagulation imbalance and neurocognitive functioning in older HIV-positive adults on suppressive antiretroviral therapy. AIDS. 2017 Mar 27; 31(6):787-795. PMID: 28099190.
      View in: PubMed
    25. Erlandson KM, Wu K, Koletar SL, Kalayjian RC, Ellis RJ, Taiwo B, Palella FJ, Tassiopoulos K. Association Between Frailty and Components of the Frailty Phenotype With Modifiable Risk Factors and Antiretroviral Therapy. J Infect Dis. 2017 03 15; 215(6):933-937. PMID: 28453849.
      View in: PubMed
    26. Sakoda ME, Fazeli PL, Ellis RJ, Jeste DV, Grant I, Letendre SL, Moore DJ. Higher Cystatin C Levels Are Associated With Neurocognitive Impairment in Older HIV+ Adults. J Acquir Immune Defic Syndr. 2017 Mar 01; 74(3):243-249. PMID: 27861242.
      View in: PubMed
    27. Keltner JR, Connolly CG, Vaida F, Jenkinson M, Fennema-Notestine C, Archibald S, Akkari C, Schlein A, Lee J, Wang D, Kim S, Li H, Rennels A, Miller DJ, Kesidis G, Franklin DR, Sanders C, Corkran S, Grant I, Brown GG, Atkinson JH, Ellis RJ. HIV Distal Neuropathic Pain Is Associated with Smaller Ventral Posterior Cingulate Cortex. Pain Med. 2017 03 01; 18(3):428-440. PMID: 27497320.
      View in: PubMed
    28. de Almeida SM, Kamat R, Cherner M, Umlauf A, Ribeiro CE, de Pereira AP, Franklin D, Heaton RK, Ellis RJ. Improving Detection of HIV-Associated Cognitive Impairment: Comparison of the International HIV Dementia Scale and a Brief Screening Battery. J Acquir Immune Defic Syndr. 2017 03 01; 74(3):332-338. PMID: 27828876.
      View in: PubMed
    29. de Almeida SM, Rotta I, Ribeiro CE, Oliveira MF, Chaillon A, de Pereira AP, Cunha AP, Zonta M, Bents JF, Raboni SM, Smith D, Letendre S, Ellis RJ. Dynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization-case study. J Neurovirol. 2017 Jun; 23(3):460-473. PMID: 28247269.
      View in: PubMed
    30. Montoya JL, Iudicello J, Fazeli PL, Hong S, Potter M, Ellis RJ, Grant I, Letendre SL, Moore DJ. Elevated Markers of Vascular Remodeling and Arterial Stiffness Are Associated With Neurocognitive Function in Older HIV+ Adults on Suppressive Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2017 Feb 01; 74(2):134-141. PMID: 27828873.
      View in: PubMed
    31. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 Jan; 13(1):e1006112. PMID: 28046096.
      View in: PubMed
    32. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 Jan 02; 31(1):1-4. PMID: 27755112.
      View in: PubMed
    33. de Almeida SM, Rotta I, Ribeiro CE, Smith D, Wang R, Judicello J, Potter M, Vaida F, Letendre S, Ellis RJ. Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection. J Neuroimmunol. 2016 Dec 15; 301:41-48. PMID: 27836178.
      View in: PubMed
    34. Bharti AR, McCutchan A, Deutsch R, Smith DM, Ellis RJ, Cherner M, Woods SP, Heaton RK, Grant I, Letendre SL. Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults. Clin Infect Dis. 2016 Dec 15; 63(12):1655-1660. PMID: 27794019.
      View in: PubMed
    35. Anderson AM, Muñoz-Moreno JA, McClernon DR, Ellis RJ, Cookson D, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Franklin DR, Heaton RK, Grant I, Letendre SL. Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy. J Infect Dis. 2017 Jan 01; 215(1):105-113. PMID: 27789723.
      View in: PubMed
    36. Keegan MR, Chittiprol S, Letendre SL, Winston A, Fuchs D, Boasso A, Iudicello J, Ellis RJ. Tryptophan Metabolism and Its Relationship with Depression and Cognitive Impairment Among HIV-infected Individuals. Int J Tryptophan Res. 2016; 9:79-88. PMID: 27812290.
      View in: PubMed
    37. Samuels DC, Kallianpur AR, Ellis RJ, Bush WS, Letendre S, Franklin D, Grant I, Hulgan T. European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection. Pathog Immun. 2016 Fall-Winter; 1(2):330-351. PMID: 28317034.
      View in: PubMed
    38. Obermeit LC, Beltran J, Casaletto KB, Franklin DR, Letendre S, Ellis R, Fennema-Notestine C, Vaida F, Collier AC, Marra CM, Clifford D, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Grant I, Heaton RK. Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining "symptomatic" versus "asymptomatic" HAND. J Neurovirol. 2017 02; 23(1):67-78. PMID: 27557777.
      View in: PubMed
    39. Gianella S, Kosakovsky Pond SL, Oliveira MF, Scheffler K, Strain MC, De la Torre A, Letendre S, Smith DM, Ellis RJ. Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy. Virus Evol. 2016 Jul; 2(2):vew020. PMID: 27774305.
      View in: PubMed
    40. de Almeida SM, Barbosa FJ, Kamat R, de Pereira AP, Raboni SM, Rotta I, Ribeiro CE, Cherner M, Ellis RJ, Atkinson JH. Suicide risk and prevalence of major depressive disorder (MDD) among individuals infected with HIV-1 subtype C versus B in Southern Brazil. J Neurovirol. 2016 12; 22(6):789-798. PMID: 27431676.
      View in: PubMed
    41. de Almeida SM, Rotta I, Jiang Y, Li X, Raboni SM, Ribeiro CE, Smith D, Potter M, Vaida F, Letendre S, Ellis RJ. Biomarkers of chemotaxis and inflammation in cerebrospinal fluid and serum in individuals with HIV-1 subtype C versus B. J Neurovirol. 2016 12; 22(6):715-724. PMID: 27400932.
      View in: PubMed
    42. Ellis R, Letendre SL. Update and New Directions in Therapeutics for Neurological Complications of HIV Infections. Neurotherapeutics. 2016 07; 13(3):471-6. PMID: 27383150; PMCID: PMC4965416 [Available on 07/01/17].
      View in: PubMed, PubMed Central
    43. Marquine MJ, Montoya JL, Umlauf A, Fazeli PL, Gouaux B, Heaton RK, Ellis RJ, Letendre SL, Grant I, Moore DJ. The Veterans Aging Cohort Study (VACS) Index and Neurocognitive Change: A Longitudinal Study. Clin Infect Dis. 2016 Sep 01; 63(5):694-702. PMID: 27199461; PMCID: PMC4981756 [Available on 09/01/17].
      View in: PubMed, PubMed Central
    44. Bharti AR, Woods SP, Ellis RJ, Cherner M, Rosario D, Potter M, Heaton RK, Everall IP, Masliah E, Grant I, Letendre SL. Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. HIV AIDS (Auckl). 2016; 8:93-9. PMID: 27199571; PMCID: PMC4857802.
      View in: PubMed, PubMed Central
    45. Cooley SA, Paul RH, Fennema-Notestine C, Morgan EE, Vaida F, Deng Q, Chen JA, Letendre S, Ellis R, Clifford DB, Marra CM, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Morgello S, Grant I, Ances BM. Apolipoprotein E e4 genotype status is not associated with neuroimaging outcomes in a large cohort of HIV+ individuals. J Neurovirol. 2016 10; 22(5):607-614. PMID: 27021072.
      View in: PubMed
    46. Hoenigl M, de Oliveira MF, Pérez-Santiago J, Zhang Y, Morris S, McCutchan AJ, Finkelman M, Marcotte TD, Ellis RJ, Gianella S. (1?3)-ß-D-Glucan Levels Correlate With Neurocognitive Functioning in HIV-Infected Persons on Suppressive Antiretroviral Therapy: A Cohort Study. Medicine (Baltimore). 2016 Mar; 95(11):e3162. PMID: 26986173; PMCID: PMC4839954.
      View in: PubMed, PubMed Central
    47. de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. Corrigendum: Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2016 Jan 19; 6:19387. PMID: 26783252.
      View in: PubMed
    48. Hammond ER, Crum RM, Treisman GJ, Mehta SH, Clifford DB, Ellis RJ, Gelman BB, Grant I, Letendre SL, Marra CM, Morgello S, Simpson DM, Mcarthur JC. Persistent CSF but not plasma HIV RNA is associated with increased risk of new-onset moderate-to-severe depressive symptoms; a prospective cohort study. J Neurovirol. 2016 08; 22(4):479-87. PMID: 26727907.
      View in: PubMed
    49. Kallianpur AR, Wang Q, Jia P, Hulgan T, Zhao Z, Letendre SL, Ellis RJ, Heaton RK, Franklin DR, Barnholtz-Sloan J, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I. Anemia and Red Blood Cell Indices Predict HIV-Associated Neurocognitive Impairment in the Highly Active Antiretroviral Therapy Era. J Infect Dis. 2016 Apr 01; 213(7):1065-73. PMID: 26690344; PMCID: PMC4779306 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    50. Bryant AK, Fazeli PL, Letendre SL, Ellis RJ, Potter M, Burdo TH, Singh KK, Jeste DV, Grant I, Moore DJ. Complement Component 3 Is Associated with Metabolic Comorbidities in Older HIV-Positive Adults. AIDS Res Hum Retroviruses. 2016 Mar; 32(3):271-8. PMID: 26499082; PMCID: PMC4779974 [Available on 03/01/17].
      View in: PubMed, PubMed Central
    51. de Oliveira MF, Murrell B, Murrel B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2015 Nov 25; 5:17094. PMID: 26603568; PMCID: PMC4658529.
      View in: PubMed, PubMed Central
    52. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy AN, Ellis RJ, Letendre S, Grant I, Masliah E. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 Feb; 86:154-69. PMID: 26611103; PMCID: PMC4713337.
      View in: PubMed, PubMed Central
    53. de Oliveira MF, Gianella S, Letendre S, Scheffler K, Kosakovsky Pond SL, Smith DM, Strain M, Ellis RJ. Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR. PLoS One. 2015; 10(10):e0139510. PMID: 26431315.
      View in: PubMed
    54. Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TR, Ramirez-Gaona M, Suben JD, Murrell B, Massanella M, Cherner M, Smith DM, Ellis RJ, Letendre SL, Mehta SR. Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection. J Neurovirol. 2016 Apr; 22(2):191-200. PMID: 26428514; PMCID: PMC4862614 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    55. Andreae MH, Carter GM, Shaparin N, Suslov K, Ellis RJ, Ware MA, Abrams DI, Prasad H, Wilsey B, Indyk D, Johnson M, Sacks HS. Inhaled Cannabis for Chronic Neuropathic Pain: A Meta-analysis of Individual Patient Data. J Pain. 2015 Dec; 16(12):1221-1232. PMID: 26362106.
      View in: PubMed
    56. Hulgan T, Samuels DC, Bush W, Ellis RJ, Letendre SL, Heaton RK, Franklin DR, Straub P, Murdock DG, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Grant I, Kallianpur AR. Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection. Clin Infect Dis. 2015 Nov 01; 61(9):1476-84. PMID: 26129753; PMCID: PMC4599391 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    57. Lalazar G, Mizrahi M, Turgeman I, Adar T, Ben Ya'acov A, Shabat Y, Nimer A, Hemed N, Zolotarovya L, Lichtenstein Y, Lisovoder N, Samira S, Shalit I, Ellis R, Ilan Y. Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial. J Clin Immunol. 2015 May; 35(4):399-407. PMID: 25876706.
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    58. Malvar J, Vaida F, Sanders CF, Atkinson JH, Bohannon W, Keltner J, Robinson-Papp J, Simpson DM, Marra CM, Clifford DB, Gelman B, Fan J, Grant I, Ellis RJ. Predictors of new-onset distal neuropathic pain in HIV-infected individuals in the era of combination antiretroviral therapy. Pain. 2015 Apr; 156(4):731-9. PMID: 25659067.
      View in: PubMed
    59. Ipser JC, Brown GG, Bischoff-Grethe A, Connolly CG, Ellis RJ, Heaton RK, Grant I. HIV infection is associated with attenuated frontostriatal intrinsic connectivity: a preliminary study. J Int Neuropsychol Soc. 2015 Mar; 21(3):203-13. PMID: 25824201; PMCID: PMC4400233.
      View in: PubMed, PubMed Central
    60. Sattler FR, He J, Letendre S, Wilson C, Sanders C, Heaton R, Ellis R, Franklin D, Aldrovandi G, Marra CM, Clifford D, Morgello S, Grant I, McCutchan JA. Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation. J Acquir Immune Defic Syndr. 2015 Mar 01; 68(3):281-8. PMID: 25469522.
      View in: PubMed
    61. Schrier RD, Hong S, Crescini M, Ellis R, Pérez-Santiago J, Spina C, Letendre S. Cerebrospinal fluid (CSF) CD8+ T-cells that express interferon-gamma contribute to HIV associated neurocognitive disorders (HAND). PLoS One. 2015; 10(2):e0116526. PMID: 25719800.
      View in: PubMed
    62. Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I. Reply to Haddow et al. Clin Infect Dis. 2015 May 01; 60(9):1442-3. PMID: 25645217; PMCID: PMC4415055.
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    63. Bryant AK, Ellis RJ, Umlauf A, Gouaux B, Soontornniyomkij V, Letendre SL, Achim CL, Masliah E, Grant I, Moore DJ. Antiretroviral therapy reduces neurodegeneration in HIV infection. AIDS. 2015 Jan 28; 29(3):323-30. PMID: 25686681; PMCID: PMC4353640.
      View in: PubMed, PubMed Central
    64. Kamat R, Cattie JE, Marcotte TD, Woods SP, Franklin DR, Corkran SH, Ellis RJ, Grant I, Heaton RK. Incident major depressive episodes increase the severity and risk of apathy in HIV infection. J Affect Disord. 2015 Apr 01; 175:475-80. PMID: 25679203; PMCID: PMC4386921.
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