Ronald Ellis

Title(s)Professor In Residence, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Williams College, Williamstown, MABA05/1982Psychology
    UC San Diego, San Diego, CA11/2018Senior Faculty Mentor Training
    Boston University, Boston, MAMD, PhD06/1989Medicine, Behavioral Neuroscience
    Collapse Awards and Honors
    UC San Diego2020Health Sciences Faculty Excellence in Mentoring Award
    SD Metro Magazine2016San Diego’s Best Doctors
    UC San Diego2009Arnold P. Gold Foundation Leonard Tow Humanism in Medicine Award. UC San Diego School of Medicine
    UC San Diego1997  - 2001Neurosciences Junior Faculty Teaching Award

    Collapse Overview 
    Collapse Overview
    Dr. Ellis’s clinical work and research are focused on the neurological manifestations of HIV infection and their pathogenesis and treatment, particularly dementia, neurocognitive disorders and sensory polyneuropathy. He is Associate Director of the NIMH-funded P03 HIV Neurobehavioral Research Programs (HNRP) and PI of its NeuroAssessment Core, which comprises a Clinical Research Support Unit (CRSU) and a Laboratory, Pharmacology and Biomarker Unit (LPBU). He also serves as an investigator in the Translational Methamphetamine AIDS Research Center (TMARC) and the Center for Medicinal Cannabis Research (CMCR). TMARC comprises an integrated program of human clinical, neuroimaging, laboratory and animal model investigations being conducted at UCSD, The Sanford-Burnham Institute, and the Scripps Institute. Dr. Ellis is Chair of the Neurology Collaborative Science Group of the AIDS Clinical Trials Group (ACTG).

    Collapse Research 
    Collapse Research Activities and Funding
    Immunometabolicgene expression profiles associated with depressed mood and behavioral domains inpeople with HIV
    NIH R01MH128869Sep 15, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Biopsychosocial Phenotypes and Potential Mechanisms in CHARTER
    NIH R01MH125720Dec 8, 2020 - Oct 31, 2025
    Role: Co-Principal Investigator
    Effect of Cannabis Administration and Endocannabinoids on HIV Neuropathic Pain
    NIH R01DA043430Feb 1, 2017 - Dec 31, 2020
    Role: Principal Investigator
    Phase II trial of tesamorelin for cognition in aging HIV-infected persons
    NIH R01AG048650Sep 30, 2015 - May 31, 2021
    Role: Principal Investigator
    A Novel FMRI Biomarker of Asymptomatic HIV-Associated Neurocognitive Disorders
    NIH R01MH108466Jul 1, 2015 - Apr 30, 2020
    Role: Co-Investigator
    Building research capacity in aging HIV-infected persons
    NIH R03AG044910Sep 30, 2013 - Jul 31, 2015
    Role: Principal Investigator
    California NeuroAIDS Tissue Network
    NIH U24MH100928May 1, 2013 - Feb 28, 2023
    Role: Co-Investigator
    Intrahost HIV population dynamics in CNS and other tissues
    NIH R01MH101012May 1, 2013 - Jan 31, 2016
    Role: Principal Investigator
    HIV Clade on Cognitive and Neurological Disorders Brazil
    NIH R21MH076651Jan 25, 2006 - Dec 31, 2009
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH P30MH062512Apr 24, 2001 - Jan 31, 2026
    Role: Co-Investigator
    NEUROAIDS: EFFECTS OF METHAMPHETAMINE AND HCV
    NIH P01DA012065Jul 1, 1999 - Apr 30, 2011
    Role: Co-Investigator
    HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART
    NIH R01MH058076Sep 30, 1997 - Jul 31, 2012
    Role: Principal Investigator
    CEREBRAL LATERALITY IN AGING ALCOHOLICS
    NIH F31AA005260Mar 1, 1987
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Faculty Mentoring

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Impact of Cannabis Use on Cognition in People with HIV: Evidence of Function-Dependent Effects and Mechanisms from Clinical and Preclinical Studies. Curr HIV/AIDS Rep. 2024 Apr 11. Ayoub SM, Holloway BM, Miranda AH, Roberts BZ, Young JW, Minassian A, Ellis RJ. PMID: 38602558.
      View in: PubMed   Mentions:
    2. Neurocognition and its predictors in a linguistically and culturally diverse cohort of people with HIV. Clin Neuropsychol. 2024 Apr 08; 1-20. Breton J, Watson CW, Kamalyan L, Franklin D, Fazeli P, Umlauf A, Moore RC, Ellis R, Grant I, Heaton RK, Cherner M, Moore DJ, Marquine MJ. PMID: 38588669.
      View in: PubMed   Mentions:
    3. Longitudinal analysis of CSF HIV RNA in untreated people with HIV: Identification of CSF controllers. J Med Virol. 2024 Mar; 96(3):e29550. Trunfio M, Tang B, Okwuegbuna O, Iudicello JE, Bharti A, Moore DJ, Gelman BB, Morgello S, Patel PB, Rubin LH, Ances BM, Gianella S, Heaton RK, Ellis RJ, Letendre SL. PMID: 38511593.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Cognitive criteria in HIV: greater consensus is needed. Nat Rev Neurol. 2024 02; 20(2):127-128. Cysique LA, Brew BJ, Bruning J, Byrd D, Costello J, Daken K, Ellis RJ, Fazeli PL, Goodkin K, Gouse H, Heaton RK, Letendre S, Levin J, Aung HL, Mindt MR, Moore D, Mullens AB, de Almeida SM, Muñoz-Moreno JA, Power C, Robbins RN, Rule J, Rajasuriar R, Savin MJ, Taylor J, Trunfio M, Vance DE, Wong PL, Woods SP, Wright EJ, Rourke SB. PMID: 38228906.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Latent Profile Analysis of Cognitive Performance and Depressive Symptoms Among People with HIV. AIDS Patient Care STDS. 2024 Feb; 38(2):93-106. Kohli M, Ham L, Saloner R, Dung D, Iudicello J, Ellis RJ, Moore DJ. PMID: 38381950.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Polypharmacy is associated with slow gait speed and recurrent falls in older people with HIV. Clin Infect Dis. 2023 Dec 26. Kosana P, Wu K, Tassiopoulos K, Letendre S, Ma Q, Paul R, Ellis R, Erlandson KM, Farhadian SF. PMID: 38147306.
      View in: PubMed   Mentions:    Fields:    
    7. Elevated Plasma Protein Carbonyl Concentration Is Associated with More Abnormal White Matter in People with HIV. Viruses. 2023 Dec 12; 15(12). Riggs PK, Anderson AM, Tang B, Rubin LH, Morgello S, Marra CM, Gelman BB, Clifford DB, Franklin D, Heaton RK, Ellis RJ, Fennema-Notestine C, Letendre SL. PMID: 38140650; PMCID: PMC10747698.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Distinct effects of SSRIs and SNRIs on Soluble Biomarkers in Blood and Cerebrospinal Fluid of people with HIV. J Infect Dis. 2023 Dec 06. Trunfio M, Tang B, Iudicello JE, Ma Q, Franklin DR, Cookson D, Riggs PK, Cherner M, Moore DJ, Heaton RK, Letendre SL, Ellis RJ. PMID: 38059529.
      View in: PubMed   Mentions:    Fields:    
    9. Publisher Correction: Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management. Nat Rev Neurol. 2023 Dec; 19(12):787. Ellis RJ, Marquine MJ, Kaul M, Fields JA, Schlachetzki JCM. PMID: 37872259.
      View in: PubMed   Mentions:    Fields:    
    10. Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV. Mitochondrion. 2024 01; 74:101820. Volpe KE, Samuels DC, Elson JL, Steyn JS, Gebretsadik T, Ellis RJ, Heaton RK, Kallianpur AR, Letendre S, Hulgan T. PMID: 37989461; PMCID: PMC10872545.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Identifying and distinguishing cognitive profiles among virally suppressed people with HIV. Neuropsychology. 2024 Feb; 38(2):169-183. Sundermann EE, Dastgheyb R, Moore DJ, Buchholz AS, Bondi MW, Ellis RJ, Letendre SL, Heaton RK, Rubin LH. PMID: 37971860.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management. Nat Rev Neurol. 2023 11; 19(11):668-687. Ellis RJ, Marquine MJ, Kaul M, Fields JA, Schlachetzki JCM. PMID: 37816937.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Reply to Augello, P.A.; Wu, J. Comment on "Rogers et al. The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition. Viruses 2023, 15, 674". Viruses. 2023 09 05; 15(9). Rogers JM, Iudicello JE, Marcondes MCG, Morgan EE, Cherner M, Ellis RJ, Letendre SL, Heaton RK, Grant I. PMID: 37766283; PMCID: PMC10534708.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. Increasing Neuroinflammation Relates to Increasing Neurodegeneration in People with HIV. Viruses. 2023 Aug 30; 15(9). Tavasoli A, Gelman BB, Marra CM, Clifford DB, Iudicello JE, Rubin LH, Letendre SL, Tang B, Ellis RJ. PMID: 37766242; PMCID: PMC10536802.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Cannabis use may attenuate neurocognitive performance deficits resulting from methamphetamine use disorder. J Int Neuropsychol Soc. 2024 Jan; 30(1):84-93. Rogers JM, Grant I, Marcondes MCG, Morgan EE, Cherner M, Ellis RJ, Letendre SL, Heaton RK, Iudicello JE. PMID: 37553288; PMCID: PMC10841263.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. Longitudinal analysis and treatment of neuropsychiatric symptoms in post-acute sequelae of COVID-19. J Neurol. 2023 Oct; 270(10):4661-4672. Liu EN, Yang JH, Patel L, Arora J, Gooding A, Ellis R, Graves JS. PMID: 37493802; PMCID: PMC10910663.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Alzheimer-type cerebral amyloidosis in the context of HIV infection: implications for a proposed new treatment approach. Res Sq. 2023 Jun 16. Ellis RJ, Pal S, Achim CL, Sundermann E, Moore DJ, Soontornniyomkij V, Feldman H. PMID: 37398361; PMCID: PMC10312930.
      View in: PubMed   Mentions:
    18. MRP8/14 Is a Molecular Signature Triggered by Dopamine in HIV Latent Myeloid Targets That Increases HIV Transcription and Distinguishes HIV+ Methamphetamine Users with Detectable CSF Viral Load and Brain Pathology. Viruses. 2023 06 13; 15(6). Basova LV, Lindsey A, McGovern A, Rosander A, Delorme-Walker V, ElShamy WM, Pendyala VV, Gaskill PJ, Ellis RJ, Cherner M, Iudicello JE, Marcondes MCG. PMID: 37376663; PMCID: PMC10304659.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Alzheimer's Disease Pathology in Middle Aged and Older People with HIV: Comparisons with Non-HIV Controls on a Healthy Aging and Alzheimer's Disease Trajectory and Relationships with Cognitive Function. Viruses. 2023 06 04; 15(6). Sundermann EE, Campbell LM, Villers O, Bondi MW, Gouaux B, Salmon DP, Galasko D, Soontornniyomkij V, Ellis RJ, Moore DJ. PMID: 37376619; PMCID: PMC10305373.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Sex-specific associations between plasma interleukin-6 and depression in persons with and without HIV. Brain Behav Immun Health. 2023 Jul; 30:100644. Petersen KJ, Yu X, Masters MC, Lobo JD, Lu T, Letendre S, Ellis RJ, McCutchan JA, Sundermann E. PMID: 37347049; PMCID: PMC10279778.
      View in: PubMed   Mentions: 1  
    21. Cerebrospinal fluid CD14++CD16+ monocytes in HIV-1 subtype C compared with subtype B. J Neurovirol. 2023 06; 29(3):308-324. de Almeida SM, Beltrame MP, Tang B, Rotta I, Abramson I, Vaida F, Schrier R, Ellis RJ. PMID: 37219809; PMCID: PMC10769008.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Evaluation of Archival HIV DNA in Brain and Lymphoid Tissues. J Virol. 2023 06 29; 97(6):e0054323. Oliveira MF, Pankow A, Vollbrecht T, Kumar NM, Cabalero G, Ignacio C, Zhao M, Vitomirov A, Gouaux B, Nakawawa M, Murrell B, Ellis RJ, Gianella S. PMID: 37184401; PMCID: PMC10308944.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. A longitudinal study of cannabis use and risk for cognitive and functional decline among older adults with HIV. AIDS Behav. 2023 Oct; 27(10):3401-3413. Watson CW, Sundermann E, Helm J, Paolillo EW, Hong S, Ellis RJ, Letendre S, Marcotte TD, Heaton RK, Morgan EE, Grant I. PMID: 37155086; PMCID: PMC10766343.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    24. Emotional health and its association with neurocognition in Hispanic and non-Hispanic White people with HIV. J Int Neuropsychol Soc. 2024 Jan; 30(1):56-66. Guareña LA, Kamalyan L, Watson CW, Karcher K, Umlauf A, Morgan E, Moore D, Ellis R, Grant I, Cherner M, Moore RC, Zlatar ZZ, Heaton RK, Marquine MJ. PMID: 37078464; PMCID: PMC10766342.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Anemia and Erythrocyte Indices Are Associated With Neurocognitive Performance Across Multiple Ability Domains in Adults With HIV. J Acquir Immune Defic Syndr. 2023 04 15; 92(5):414-421. Okwuegbuna OK, Kaur H, Jennifer I, Bush WS, Bharti A, Umlauf A, Ellis RJ, Franklin DR, Heaton RK, McCutchan JA, Kallianpur AR, Letendre SL. PMID: 36580636; PMCID: PMC10006328.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Signatures of HIV and Major Depressive Disorder in the Plasma Microbiome. Microorganisms. 2023 Apr 14; 11(4). Taylor BC, Sheikh Andalibi M, Wandro S, Weldon KC, Sepich-Poore GD, Carpenter CS, Fraraccio S, Franklin D, Iudicello JE, Letendre S, Gianella S, Grant I, Ellis RJ, Heaton RK, Knight R, Swafford AD. PMID: 37110445; PMCID: PMC10146336.
      View in: PubMed   Mentions: 1  
    27. Subacute myoclonic measles encephalitis - An opportunistic HIV-associated infection. Front Cell Neurosci. 2023; 17:1113935. Ene L, Duiculescu D, Radoi R, Lazar M, Tardei G, Ungureanu E, Ruta S, Vinters HV, Letendre S, Grant I, Ellis RJ, Achim CL. PMID: 37082207; PMCID: PMC10110848.
      View in: PubMed   Mentions:
    28. Higher Levels of Cerebrospinal Fluid and Plasma Neurofilament Light in Human Immunodeficiency Virus-Associated Distal Sensory Polyneuropathy. Clin Infect Dis. 2023 03 21; 76(6):1103-1109. Ellis RJ, Chenna A, Lie Y, Curanovic D, Winslow J, Tang B, Marra CM, Rubin LH, Clifford DB, McCutchan JA, Gelman BB, Robinson-Papp J, Petropoulos CJ, Letendre SL. PMID: 36310512; PMCID: PMC10226757.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. CD3+CD56+ and CD3-CD56+ lymphocytes in the cerebrospinal fluid of persons with HIV-1 subtypes B and C. J Neuroimmunol. 2023 04 15; 377:578067. de Almeida SM, Beltrame MP, Tang B, Rotta I, Justus JLP, Schluga Y, da Rocha MT, Martins E, Liao A, Abramson I, Vaida F, Schrier R, Ellis RJ. PMID: 36965365; PMCID: PMC10817703.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. PKR-like ER kinase (PERK) Haplotypes Are Associated with Depressive Symptoms in People with HIV. J Neurol Psychol. 2023; 10(1). Haddadi S, Jordan-Sciutto KL, Akay-Espinoza C, Grelotti D, Letendre SL, Tang B, Ellis RJ. PMID: 37206541; PMCID: PMC10194542.
      View in: PubMed   Mentions:
    31. The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition. Viruses. 2023 03 03; 15(3). Rogers JM, Iudicello JE, Marcondes MCG, Morgan EE, Cherner M, Ellis RJ, Letendre SL, Heaton RK, Grant I. PMID: 36992383; PMCID: PMC10058939.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    32. Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study. Brain. 2023 03 01; 146(3):1121-1131. Heaton RK, Ellis RJ, Tang B, Marra CM, Rubin LH, Clifford DB, McCutchan JA, Gelman BB, Morgello S, Franklin DR, Letendre SL. PMID: 36477867; PMCID: PMC10169412.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Time of Day Influences Concentrations of Total Protein and Albumin in Cerebrospinal Fluid in HIV. Int J Mol Sci. 2023 Feb 01; 24(3). Kakarla V, Letendre SL, Ellis RJ. PMID: 36769155; PMCID: PMC9917345.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    34. Cannabis Use Is Associated With Decreased Antiretroviral Therapy Adherence Among Older Adults With HIV. Open Forum Infect Dis. 2023 Jan; 10(1):ofac699. Manuzak JA, Granche J, Tassiopoulos K, Rower JE, Knox JR, Williams DW, Ellis RJ, Goodkin K, Sharma A, Erlandson KM, AIDS Clinical Trials Group (ACTG) A5322 Study Team. PMID: 36726540; PMCID: PMC9879711.
      View in: PubMed   Mentions: 1  
    35. Astrocyte Activation is A Potential Mechanism Underlying Depressed Mood and Apathy in People with HIV. J Neurol Psychol. 2022; 9(1). Ellis RJ, Fan Y, Grelotti D, Tang B, Letendre S, He JJ. PMID: 37205974; PMCID: PMC10194432.
      View in: PubMed   Mentions: 2  
    36. Plasma biomarkers of vascular dysfunction uniquely relate to a vascular-risk profile of neurocognitive deficits in virally-suppressed adults with HIV. Brain Behav Immun Health. 2022 Dec; 26:100560. Saloner R, Sun-Suslow N, Morgan EE, Lobo J, Cherner M, Ellis RJ, Heaton RK, Grant I, Letendre SL, Iudicello JE, TMARC Group. PMID: 36439059; PMCID: PMC9685288.
      View in: PubMed   Mentions: 2  
    37. Distal neuropathic pain in HIV is associated with functional connectivity patterns in default mode and salience networks. Front Pain Res (Lausanne). 2022; 3:1004060. Hays Weeks CC, Simmons AN, Strigo IA, Timtim S, Ellis RJ, Keltner JR. PMID: 36313219; PMCID: PMC9596968.
      View in: PubMed   Mentions: 2  
    38. HIV peripheral neuropathy-related degeneration of white matter tracts to sensorimotor cortex. J Neurovirol. 2022 12; 28(4-6):505-513. Timtim SH, Simmons AN, Hays C, Strigo I, Sorg S, Ellis R, Keltner JR. PMID: 36207560; PMCID: PMC9797459.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    39. Cognitive and Physiologic Reserve Independently Relate to Superior Neurocognitive Abilities in Adults Aging With HIV. J Acquir Immune Defic Syndr. 2022 08 01; 90(4):440-448. Saloner R, Lobo JD, Paolillo EW, Campbell LM, Letendre SL, Cherner M, Grant I, Heaton RK, Ellis RJ, Moore DJ, CHARTER Study Group. PMID: 35364601; PMCID: PMC9246889.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Association of Plasma Eicosanoid Levels With Immune, Viral, and Cognitive Outcomes in People With HIV. Neurology. 2022 09 20; 99(12):e1251-e1264. Deme P, Moniruzzaman M, Moore D, Heaton R, Ellis R, Letendre S, Haughey N. PMID: 35851253; PMCID: PMC9576290.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Neuropathic pain correlates with worsening cognition in people with human immunodeficiency virus. Brain. 2022 06 30; 145(6):2206-2213. Ellis RJ, Sacktor N, Clifford DB, Marra CM, Collier AC, Gelman B, Robinson-Papp J, Letendre SL, Heaton RK, CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group. PMID: 35773234; PMCID: PMC9630658.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    42. Longitudinal evaluation of neurologic-post acute sequelae SARS-CoV-2 infection symptoms. Ann Clin Transl Neurol. 2022 07; 9(7):995-1010. Shanley JE, Valenciano AF, Timmons G, Miner AE, Kakarla V, Rempe T, Yang JH, Gooding A, Norman MA, Banks SJ, Ritter ML, Ellis RJ, Horton L, Graves JS. PMID: 35702954; PMCID: PMC9268882.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    43. Higher cerebrospinal fluid biomarkers of neuronal injury in HIV-associated neurocognitive impairment. J Neurovirol. 2022 06; 28(3):438-445. Ellis RJ, Chenna A, Petropoulos CJ, Lie Y, Curanovic D, Crescini M, Winslow J, Sundermann E, Tang B, Letendre SL. PMID: 35674935; PMCID: PMC9470698.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    44. Cingulate transcranial direct current stimulation in adults with HIV. PLoS One. 2022; 17(6):e0269491. Jiang X, Dahmani S, Bronshteyn M, Yang FN, Ryan JP, Gallagher RC, Damera SR, Kumar PN, Moore DJ, Ellis RJ, Turkeltaub PE. PMID: 35658059; PMCID: PMC9165807.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Toward Composite Pain Biomarkers of Neuropathic Pain-Focus on Peripheral Neuropathic Pain. Front Pain Res (Lausanne). 2022; 3:869215. Diaz MM, Caylor J, Strigo I, Lerman I, Henry B, Lopez E, Wallace MS, Ellis RJ, Simmons AN, Keltner JR. PMID: 35634449; PMCID: PMC9130475.
      View in: PubMed   Mentions: 6  
    46. Association Between VACS Index and Health-Related Quality of Life in Persons with HIV: Moderating Role of Fruit and Vegetable Consumption. Int J Behav Med. 2023 Jun; 30(3):356-365. Campbell LM, Montoya JL, Fazeli PL, Marquine MJ, Ellis RJ, Jeste DV, Moore DJ, Moore RC. PMID: 35534722; PMCID: PMC9643666.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    47. Ethnic/Racial Disparities in Longitudinal Neurocognitive Decline in People With HIV. J Acquir Immune Defic Syndr. 2022 05 01; 90(1):97-105. Wei-Ming Watson C, Kamalyan L, Tang B, Hussain MA, Cherner M, Rivera Mindt M, Byrd DA, Franklin DR, Collier AC, Clifford DB, Gelman B, Morgello S, McCutchan JA, Ellis RJ, Grant I, Heaton RK, Marquine MJ, CHARTER Group. PMID: 35081558; PMCID: PMC8986565.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. Higher Cerebrospinal Fluid Soluble Urokinase-type Plasminogen Activator Receptor, But Not Interferon γ-inducible Protein 10, Correlate With Higher Working Memory Deficits. J Acquir Immune Defic Syndr. 2022 05 01; 90(1):106-114. De Almeida SM, Rotta I, Tang B, Umlauf A, Vaida F, Cherner M, Franklin D, Letendre S, Ellis RJ, HNRC Group. PMID: 35090158; PMCID: PMC8986587.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    49. Higher Comorbidity Burden Predicts Worsening Neurocognitive Trajectories in People with Human Immunodeficiency Virus. Clin Infect Dis. 2022 04 28; 74(8):1323-1328. Ellis RJ, Paolillo E, Saloner R, Heaton RK. PMID: 34329400; PMCID: PMC9049252.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. Soluble CD14 is subtype-dependent in serum but not in cerebrospinal fluid in people with HIV. J Neuroimmunol. 2022 05 15; 366:577845. de Almeida SM, Tang B, Vaida F, Letendre S, Ellis RJ, HNRC Group. PMID: 35313166; PMCID: PMC10373575.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    51. Peripheral inflammation and depressed mood independently predict neurocognitive worsening over 12 years. Brain Behav Immun Health. 2022 May; 21:100437. Ellis RJ, Heaton RK, Tang B, Collier AC, Marra CM, Gelman BB, Morgello S, Clifford DB, Sacktor N, Cookson D, Letendre S. PMID: 35308084; PMCID: PMC8928134.
      View in: PubMed   Mentions: 1  
    52. Main lymphocyte subpopulations in cerebrospinal fluid and peripheral blood in HIV-1 subtypes C and B. J Neurovirol. 2022 04; 28(2):291-304. de Almeida SM, Beltrame MP, Tang B, Rotta I, Schluga Y, Justus JLP, da Rocha MT, Abramson I, Vaida F, Schrier R, Ellis RJ. PMID: 35190973.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    53. Higher buccal mitochondrial DNA and mitochondrial common deletion number are associated with markers of neurodegeneration and inflammation in cerebrospinal fluid. J Neurovirol. 2022 04; 28(2):281-290. Solanky D, Fields JA, Iudicello JE, Ellis RJ, Franklin D, Clifford DB, Gelman BB, Marra CM, Morgello S, Rubin LH, Grant I, Heaton RK, Letendre SL, Mehta SR. PMID: 35157246; PMCID: PMC9352370.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. CSF markers of AD-related pathology relate specifically to memory impairment in older people with HIV: a pilot study. J Neurovirol. 2022 02; 28(1):162-167. Lobo JD, Moore DJ, Bondi MW, Soontornniyomkij V, Soontornniyomkij B, Gouaux B, Achim CL, Ellis RJ, Sundermann EE. PMID: 35103880; PMCID: PMC9081235.
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    63. Association of painful human immunodeficiency virus distal sensory polyneuropathy with aberrant expectation of pain relief: functional magnetic resonance imaging evidence. Brain Commun. 2021; 3(4):fcab260. Strigo IA, Keltner JR, Ellis RJ, Simmons AN. PMID: 34859214; PMCID: PMC8633742.
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    357. The effects of hepatitis C, HIV, and methamphetamine dependence on neuropsychological performance: biological correlates of disease. AIDS. 2005 Oct; 19 Suppl 3:S72-8. Letendre SL, Cherner M, Ellis RJ, Marquie-Beck J, Gragg B, Marcotte T, Heaton RK, McCutchan JA, Grant I, HNRC Group. PMID: 16251831.
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    358. Dynamics of monocyte chemoattractant protein type one (MCP-1) and HIV viral load in human cerebrospinal fluid and plasma. J Neuroimmunol. 2005 Dec; 169(1-2):144-52. Monteiro de Almeida S, Letendre S, Zimmerman J, Lazzaretto D, McCutchan A, Ellis R. PMID: 16182380.
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    359. A battery approach for measuring neuropsychological change. Arch Clin Neuropsychol. 2006 Jan; 21(1):83-9. Woods SP, Childers M, Ellis RJ, Guaman S, Grant I, Heaton RK, HIV Neurobehavioral Research Center (HNRC) Group. PMID: 16169705.
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    360. Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors. J Neurovirol. 2005 Aug; 11(4):356-64. Schweinsburg BC, Taylor MJ, Alhassoon OM, Gonzalez R, Brown GG, Ellis RJ, Letendre S, Videen JS, McCutchan JA, Patterson TL, Grant I, HNRC Group. PMID: 16206458.
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    361. Effects of methamphetamine dependence and HIV infection on cerebral morphology. Am J Psychiatry. 2005 Aug; 162(8):1461-72. Jernigan TL, Gamst AC, Archibald SL, Fennema-Notestine C, Mindt MR, Marcotte TD, Marcotte TL, Heaton RK, Ellis RJ, Grant I. PMID: 16055767.
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    362. Lopinavir concentrations in cerebrospinal fluid exceed the 50% inhibitory concentration for HIV. AIDS. 2005 Jun 10; 19(9):949-52. Capparelli EV, Holland D, Okamoto C, Gragg B, Durelle J, Marquie-Beck J, van den Brande G, Ellis R, Letendre S, HNRC Group. PMID: 15905676.
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    363. Population pharmacokinetics of abacavir in plasma and cerebrospinal fluid. Antimicrob Agents Chemother. 2005 Jun; 49(6):2504-6. Capparelli EV, Letendre SL, Ellis RJ, Patel P, Holland D, McCutchan JA. PMID: 15917556; PMCID: PMC1140502.
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    364. Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol. 2005 Feb; 79(3):1772-88. Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. PMID: 15650202; PMCID: PMC544082.
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    365. CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults. J Neuroimmunol. 2004 Dec; 157(1-2):185-92. Singh KK, Ellis RJ, Marquie-Beck J, Letendre S, Heaton RK, Grant I, Spector SA. PMID: 15579296.
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    366. The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid. J Neuroimmunol. 2004 Dec; 157(1-2):193-6. Letendre S, Marquie-Beck J, Singh KK, de Almeida S, Zimmerman J, Spector SA, Grant I, Ellis R, HNRC Group. PMID: 15579297.
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    367. Regional patterns of brain metabolites in AIDS dementia complex. Neuroimage. 2004 Nov; 23(3):928-35. Yiannoutsos CT, Ernst T, Chang L, Lee PL, Richards T, Marra CM, Meyerhoff DJ, Jarvik JG, Kolson D, Schifitto G, Ellis RJ, Swindells S, Simpson DM, Miller EN, Gonzalez RG, Navia BA. PMID: 15528093.
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    368. A multimodal assessment of driving performance in HIV infection. Neurology. 2004 Oct 26; 63(8):1417-22. Marcotte TD, Wolfson T, Rosenthal TJ, Heaton RK, Gonzalez R, Ellis RJ, Grant I, HIV Neurobehavioral Research Center Group. PMID: 15505158.
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    369. Altered P-glycoprotein expression in AIDS patients with HIV encephalitis. J Neuropathol Exp Neurol. 2004 Oct; 63(10):1038-47. Langford D, Grigorian A, Hurford R, Adame A, Ellis RJ, Hansen L, Masliah E. PMID: 15535131.
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    370. Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders. Ann Neurol. 2004 Sep; 56(3):416-23. Letendre SL, McCutchan JA, Childers ME, Woods SP, Lazzaretto D, Heaton RK, Grant I, Ellis RJ, HNRC Group. PMID: 15349869.
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    371. Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss. Arch Neurol. 2004 Mar; 61(3):369-76. Archibald SL, Masliah E, Fennema-Notestine C, Marcotte TD, Ellis RJ, McCutchan JA, Heaton RK, Grant I, Mallory M, Miller A, Jernigan TL. PMID: 15023814.
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    372. Effects of HIV-1 infection and aging on neurobehavioral functioning: preliminary findings. AIDS. 2004 Jan 01; 18 Suppl 1:S27-34. Cherner M, Ellis RJ, Lazzaretto D, Young C, Mindt MR, Atkinson JH, Grant I, Heaton RK, HIV Neurobehavioral Research Center Group. PMID: 15075495.
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    373. Patterns of selective neuronal damage in methamphetamine-user AIDS patients. J Acquir Immune Defic Syndr. 2003 Dec 15; 34(5):467-74. Langford D, Adame A, Grigorian A, Grant I, McCutchan JA, Ellis RJ, Marcotte TD, Masliah E, HIV Neurobehavioral Research Center Group. PMID: 14657756.
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    374. Increased human immunodeficiency virus loads in active methamphetamine users are explained by reduced effectiveness of antiretroviral therapy. J Infect Dis. 2003 Dec 15; 188(12):1820-6. Ellis RJ, Childers ME, Cherner M, Lazzaretto D, Letendre S, Grant I, HIV Neurobehavioral Research Center Group. PMID: 14673760.
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    375. Prediction of incident neurocognitive impairment by plasma HIV RNA and CD4 levels early after HIV seroconversion. Arch Neurol. 2003 Oct; 60(10):1406-12. Marcotte TD, Deutsch R, McCutchan JA, Moore DJ, Letendre S, Ellis RJ, Wallace MR, Heaton RK, Grant I, San Diego HIV Neurobehavioral Research Center (HNRC) Group. PMID: 14568811.
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    376. Human immunodeficiency virus-1 RNA levels in cerebrospinal fluid exhibit a set point in clinically stable patients not receiving antiretroviral therapy. J Infect Dis. 2003 Jun 01; 187(11):1818-21. Ellis RJ, Childers ME, Zimmerman JD, Frost SD, Deutsch R, McCutchan JA, HIV Neurobehavioral Research Center Group. PMID: 12751041.
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    377. Molecular chaperones: Plugging the transport gap. Nature. 2003 Feb 20; 421(6925):801-2. Ellis RJ. PMID: 12594497.
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    378. Computerized reaction time battery versus a traditional neuropsychological battery: detecting HIV-related impairments. J Int Neuropsychol Soc. 2003 Jan; 9(1):64-71. Gonzalez R, Heaton RK, Moore DJ, Letendre S, Ellis RJ, Wolfson T, Marcotte T, Cherner M, Rippeth J, Grant I, HIV Neurobehavioral Research Center Group. PMID: 12570359.
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    379. Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology. 2002 May 14; 58(9):1439; author reply 1439-40. Espey MG, Basile AS, Heaton RK, Ellis RJ. PMID: 12011305.
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    380. Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy. AIDS. 2002 May 03; 16(7):1019-29. Langford TD, Letendre SL, Marcotte TD, Ellis RJ, McCutchan JA, Grant I, Mallory ME, Hansen LA, Archibald S, Jernigan T, Masliah E, HNRC Group. PMID: 11953468; PMCID: PMC3548569.
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    381. Medicine: danger--misfolding proteins. Nature. 2002 Apr 04; 416(6880):483-4. Ellis RJ, Pinheiro TJ. PMID: 11932723.
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    382. Indinavir population pharmacokinetics in plasma and cerebrospinal fluid. The HIV Neurobehavioral Research Center Group. Antimicrob Agents Chemother. 2000 Aug; 44(8):2173-5. Letendre SL, Capparelli EV, Ellis RJ, McCutchan JA. PMID: 10898694; PMCID: PMC90032.
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    383. Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology. 2000 Feb 22; 54(4):927-36. Ellis RJ, Gamst AC, Capparelli E, Spector SA, Hsia K, Wolfson T, Abramson I, Grant I, McCutchan JA. PMID: 10690988.
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    384. The impact of HIV-related neuropsychological dysfunction on driving behavior. The HNRC Group. J Int Neuropsychol Soc. 1999 Nov; 5(7):579-92. Marcotte TD, Heaton RK, Wolfson T, Taylor MJ, Alhassoon O, Arfaa K, Ellis RJ, Grant I. PMID: 10645701.
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    385. Cerebrospinal fluid tau protein is not elevated in HIV-associated neurologic disease in humans. HIV Neurobehavioral Research Center Group (HNRC). Neurosci Lett. 1998 Sep 18; 254(1):1-4. Ellis RJ, Seubert P, Motter R, Galasko D, Deutsch R, Heaton RK, Heyes MP, McCutchan JA, Atkinson JH, Grant I. PMID: 9780077.
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    386. Pulmonary embolus masquerading as pneumonia in a patient with Hodgkin's disease and nephrotic syndrome. South Med J. 1998 Mar; 91(3):283-6. Ellis RJ, Cosby RL, Lees JA. PMID: 9521373.
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    387. Diagnostic validity of the dementia questionnaire for Alzheimer disease. Arch Neurol. 1998 Mar; 55(3):360-5. Ellis RJ, Jan K, Kawas C, Koller WC, Lyons KE, Jeste DV, Hansen LA, Thal LJ. PMID: 9520010.
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    388. Progressive cerebral volume loss in human immunodeficiency virus infection: a longitudinal volumetric magnetic resonance imaging study. HIV Neurobehavioral Research Center Group. Arch Neurol. 1998 Feb; 55(2):161-8. Stout JC, Ellis RJ, Jernigan TL, Archibald SL, Abramson I, Wolfson T, McCutchan JA, Wallace MR, Atkinson JH, Grant I. PMID: 9482357.
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    389. Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol. 1997 Dec; 42(6):963-72. Masliah E, Heaton RK, Marcotte TD, Ellis RJ, Wiley CA, Mallory M, Achim CL, McCutchan JA, Nelson JA, Atkinson JH, Grant I. PMID: 9403489.
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    390. Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group. Ann Neurol. 1997 Nov; 42(5):679-88. Ellis RJ, Hsia K, Spector SA, Nelson JA, Heaton RK, Wallace MR, Abramson I, Atkinson JH, Grant I, McCutchan JA. PMID: 9392566.
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    391. Types of cerebrovascular lesions associated with severe cerebral amyloid angiopathy in Alzheimer's disease. Ann N Y Acad Sci. 1997 Sep 26; 826:493-7. Olichney JM, Ellis RJ, Katzman R, Sabbagh MN, Hansen L. PMID: 9329731.
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    392. Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group. Arch Neurol. 1997 Apr; 54(4):416-24. Ellis RJ, Deutsch R, Heaton RK, Marcotte TD, McCutchan JA, Nelson JA, Abramson I, Thal LJ, Atkinson JH, Wallace MR, Grant I. PMID: 9109743.
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    393. Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV. Neurology. 1996 Jun; 46(6):1592-6. Ellis RJ, Olichney JM, Thal LJ, Mirra SS, Morris JC, Beekly D, Heyman A. PMID: 8649554.
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    394. Extrapyramidal motor signs in clinically diagnosed Alzheimer disease. Alzheimer Dis Assoc Disord. 1996; 10(2):103-14. Ellis RJ, Caligiuri M, Galasko D, Thal LJ. PMID: 8727172.
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    395. The HNRC 500--neuropsychology of HIV infection at different disease stages. HIV Neurobehavioral Research Center. J Int Neuropsychol Soc. 1995 May; 1(3):231-51. Heaton RK, Grant I, Butters N, White DA, Kirson D, Atkinson JH, McCutchan JA, Taylor MJ, Kelly MD, Ellis RJ, et al. PMID: 9375218.
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    396. Aseptic meningitis as a complication of intravenous immunoglobulin therapy for myasthenia gravis. Muscle Nerve. 1994 Jun; 17(6):683-4. Ellis RJ, Swendson MR, Bajorek J. PMID: 8196714.
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