Loading...

Ronald Ellis

Title(s)Professor In Residence, Neurosciences
SchoolHealth Sciences
Phone619-543-5079
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Williams College, Williamstown, MABA05/1982Psychology
    UC San Diego, San Diego, CA11/2018Senior Faculty Mentor Training
    Boston University, Boston, MAMD, PhD06/1989Medicine, Behavioral Neuroscience
    Collapse Awards and Honors
    UC San Diego2009Arnold P. Gold Foundation Leonard Tow Humanism in Medicine Award. UC San Diego School of Medicine
    UC San Diego1997  - 2001Neurosciences Junior Faculty Teaching Award

    Collapse Overview 
    Collapse Overview
    Dr. Ellis’s clinical work and research are focused on the neurological manifestations of HIV infection and their pathogenesis and treatment, particularly dementia, neurocognitive disorders and sensory polyneuropathy. He is Associate Director of the NIMH-funded P03 HIV Neurobehavioral Research Programs (HNRP) and PI of its NeuroAssessment Core, which comprises a Clinical Research Support Unit (CRSU) and a Laboratory, Pharmacology and Biomarker Unit (LPBU). He also serves as an investigator in the Translational Methamphetamine AIDS Research Center (TMARC) and the Center for Medicinal Cannabis Research (CMCR). TMARC comprises an integrated program of human clinical, neuroimaging, laboratory and animal model investigations being conducted at UCSD, The Sanford-Burnham Institute, and the Scripps Institute. Dr. Ellis is Chair of the Neurology Collaborative Science Group of the AIDS Clinical Trials Group (ACTG).

    Collapse Research 
    Collapse Research Activities and Funding
    Effect of Cannabis Administration and Endocannabinoids on HIV Neuropathic Pain
    NIH/NIDA R01DA043430Feb 1, 2017 - Dec 31, 2020
    Role: Principal Investigator
    Phase II trial of tesamorelin for cognition in aging HIV-infected persons
    NIH/NIA R01AG048650Sep 30, 2015 - May 31, 2020
    Role: Principal Investigator
    A Novel FMRI Biomarker of Asymptomatic HIV-Associated Neurocognitive Disorders
    NIH R01MH108466Jul 1, 2015 - Apr 30, 2020
    Role: Co-Investigator
    Building research capacity in aging HIV-infected persons
    NIH/NIA R03AG044910Sep 30, 2013 - Jul 31, 2015
    Role: Principal Investigator
    California NeuroAIDS Tissue Network
    NIH/NIMH U24MH100928May 1, 2013 - Feb 28, 2023
    Role: Co-Investigator
    Intrahost HIV population dynamics in CNS and other tissues
    NIH/NIMH R01MH101012May 1, 2013 - Jan 31, 2016
    Role: Principal Investigator
    HIV Clade on Cognitive and Neurological Disorders Brazil
    NIH/NIMH R21MH076651Jan 25, 2006 - Dec 31, 2009
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH/NIMH P30MH062512Apr 24, 2001 - Feb 28, 2021
    Role: Co-Investigator
    NEUROAIDS: EFFECTS OF METHAMPHETAMINE AND HCV
    NIH/NIDA P01DA012065Jul 1, 1999 - Apr 30, 2011
    Role: Co-Investigator
    HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART
    NIH/NIMH R01MH058076Sep 30, 1997 - Jul 31, 2012
    Role: Principal Investigator
    CEREBRAL LATERALITY IN AGING ALCOHOLICS
    NIH/NIAAA F31AA005260Mar 1, 1987
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Websites
    Collapse Faculty Mentoring
    Collapse Featured Presentations
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Saloner R, Heaton RK, Campbell LM, Chen A, Franklin D, Ellis RJ, Collier AC, Marra C, Clifford DB, Gelman B, Sacktor N, Morgello S, Mccutchan JA, Letendre S, Grant I, Fennema-Notestine C. Effects of comorbidity burden and Age on brain integrity in HIV. AIDS. 2019 Mar 11. PMID: 30870195.
      View in: PubMed
    2. Pérez-Valero I, Ellis R, Heaton R, Deutsch R, Franklin D, Clifford DB, Collier A, Gelman B, Marra C, McCutchan JA, Navis A, Sacktor N, Simpson D, Grant I, Letendre S. Cerebrospinal fluid viral escape in aviremic HIV-infected patients receiving antiretroviral therapy: prevalence, risk factors and neurocognitive effects. AIDS. 2019 Mar 01; 33(3):475-481. PMID: 30702516.
      View in: PubMed
    3. Jumare J, El-Kamary SS, Magder L, Hungerford L, Umlauf A, Franklin D, Ghate M, Abimiku A, Charurat M, Letendre S, Ellis RJ, Mehendale S, Blattner WA, Royal W, Marcotte TD, Heaton RK, Grant I, McCutchan JA. Brief Report: Body Mass Index and Cognitive Function Among HIV-1-Infected Individuals in China, India, and Nigeria. J Acquir Immune Defic Syndr. 2019 Feb 01; 80(2):e30-e35. PMID: 30422905.
      View in: PubMed
    4. Chow FC, Makanjuola A, Wu K, Berzins B, Kim KA, Ogunniyi A, Ellis RJ, Robertson K, Tassiopoulos K, Taiwo BO. Physical Activity Is Associated With Lower Odds of Cognitive Impairment in Women but Not Men Living With Human Immunodeficiency Virus Infection. J Infect Dis. 2019 Jan 07; 219(2):264-274. PMID: 30137500.
      View in: PubMed
    5. Sakabumi DZ, Moore RC, Tang B, Delaney PA, Keltner JR, Ellis RJ. Chronic Distal Sensory Polyneuropathy is a Major Contributor to Balance Disturbances in Persons Living with HIV. J Acquir Immune Defic Syndr. 2019 Jan 03. PMID: 30649035.
      View in: PubMed
    6. Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus. Clin Infect Dis. 2019 Jan 01; 68(1):131-138. PMID: 29788039.
      View in: PubMed
    7. Montoya JL, Campbell LM, Paolillo EW, Ellis RJ, Letendre SL, Jeste DV, Moore DJ. Inflammation Relates to Poorer Complex Motor Performance Among Adults Living With HIV on Suppressive Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2019 Jan 01; 80(1):15-23. PMID: 30365450.
      View in: PubMed
    8. Tierney SM, Woods SP, Sheppard D, Ellis RJ. Extrapyramidal motor signs in older adults with HIV disease: frequency, 1-year course, and associations with activities of daily living and quality of life. J Neurovirol. 2018 Dec 10. PMID: 30535869.
      View in: PubMed
    9. Hulgan T, Kallianpur AR, Guo Y, Barnholtz-Sloan JS, Gittleman H, Brown TT, Ellis R, Letendre S, Heaton RK, Samuels DC. Peripheral blood mitochondrial DNA copy number obtained from genome-wide genotype data is associated with neurocognitive impairment in persons with chronic HIV infection. J Acquir Immune Defic Syndr. 2018 Nov 29. PMID: 30531306.
      View in: PubMed
    10. Sundermann EE, Heaton RK, Pasipanodya E, Moore RC, Paolillo EW, Rubin LH, Ellis R, Moore DJ. Sex differences in HIV-associated cognitive impairment. AIDS. 2018 Nov 28; 32(18):2719-2726. PMID: 30407251.
      View in: PubMed
    11. Anderson AM, Nguyen ML, Potter M, Rosario D, Kempinska K, Ellis RJ, Diccianni M, Letendre SL. Comparison of bead array and glass nanoreactor multi-analyte platforms for the evaluation of CNS and peripheral inflammatory markers during HIV infection. J Immunol Methods. 2019 Feb; 465:7-12. PMID: 30468733.
      View in: PubMed
    12. Rubtsova AA, Marquine MJ, Depp C, Holstad M, Ellis RJ, Letendre S, Jeste DV, Moore DJ. Psychosocial Correlates of Frailty Among HIV-Infected and HIV-Uninfected Adults. Behav Med. 2018 Nov 15; 1-11. PMID: 30431403.
      View in: PubMed
    13. MacDuffie KE, Brown GG, McKenna BS, Liu TT, Meloy MJ, Tawa B, Archibald S, Fennema-Notestine C, Atkinson JH, Ellis RJ, Letendre SL, Hesselink JR, Cherner M, Grant I. Effects of HIV Infection, methamphetamine dependence and age on cortical thickness, area and volume. Neuroimage Clin. 2018; 20:1044-1052. PMID: 30342393.
      View in: PubMed
    14. Alakkas A, Ellis RJ, Watson CW, Umlauf A, Heaton RK, Letendre S, Collier A, Marra C, Clifford DB, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Kallianpur A, Gianella S, Marcotte T, Grant I, Fennema-Notestine C. White matter damage, neuroinflammation, and neuronal integrity in HAND. J Neurovirol. 2018 Oct 05. PMID: 30291567.
      View in: PubMed
    15. Mukerji SS, Misra V, Lorenz DR, Uno H, Morgello S, Franklin D, Ellis RJ, Letendre S, Gabuzda D. Impact of Antiretroviral Regimens on Cerebrospinal Fluid Viral Escape in a Prospective Multicohort Study of Antiretroviral Therapy-Experienced Human Immunodeficiency Virus-1-Infected Adults in the United States. Clin Infect Dis. 2018 Sep 28; 67(8):1182-1190. PMID: 29617912.
      View in: PubMed
    16. Soontornniyomkij V, Umlauf A, Soontornniyomkij B, Gouaux B, Ellis RJ, Levine AJ, Moore DJ, Letendre SL. Association of antiretroviral therapy with brain aging changes among HIV-infected adults. AIDS. 2018 Sep 10; 32(14):2005-2015. PMID: 29912063.
      View in: PubMed
    17. de Almeida SM, Oliveira MF, Chaillon A, Rotta I, Ribeiro CE, de Pereira AP, Smith D, Letendre S, Ellis RJ. Transient and asymptomatic meningitis in human immunodeficiency virus-1 subtype C: a case study of genetic compartmentalization and biomarker dynamics. J Neurovirol. 2018 Dec; 24(6):786-796. PMID: 30194587.
      View in: PubMed
    18. Basova L, Najera JA, Bortell N, Wang D, Moya R, Lindsey A, Semenova S, Ellis RJ, Marcondes MCG. Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection. PLoS One. 2018; 13(6):e0199861. PMID: 29944719.
      View in: PubMed
    19. Oppenheim H, Paolillo EW, Moore RC, Ellis RJ, Letendre SL, Jeste DV, Grant I, Moore DJ. Neurocognitive functioning predicts frailty index in HIV. Neurology. 2018 Jul 10; 91(2):e162-e170. PMID: 29875216.
      View in: PubMed
    20. Chow FC, Wilson MR, Wu K, Ellis RJ, Bosch RJ, Linas BP. Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort. AIDS. 2018 Jun 01; 32(9):1125-1135. PMID: 29746317.
      View in: PubMed
    21. de Almeida SM, Tang B, Ribeiro CE, Rotta I, Vaida F, Piovesan M, Batistela Fernandes MS, Letendre S, Potter M, Ellis RJ. Neprilysin in the Cerebrospinal Fluid and Serum of Patients Infected With HIV1-Subtypes C and B. J Acquir Immune Defic Syndr. 2018 Jun 01; 78(2):248-256. PMID: 29481488.
      View in: PubMed
    22. McGehrin K, Konersman C, Ellis R. Clinical Reasoning: A 22-year-old postpartum woman with new-onset seizures and headache. Neurology. 2018 May 01; 90(18):e1631-e1635. PMID: 29712815.
      View in: PubMed
    23. Dufour CA, Marquine MJ, Fazeli PL, Umlauf A, Henry BL, Zlatar Z, Montoya JL, Ellis RJ, Grant I, Moore DJ. A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults. AIDS Behav. 2018 May; 22(5):1562-1572. PMID: 27990580.
      View in: PubMed
    24. Anderson AM, Croteau D, Ellis RJ, Rosario D, Potter M, Guillemin GJ, Brew BJ, Woods SP, Letendre SL. HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau. J Neuroimmunol. 2018 Jun 15; 319:13-18. PMID: 29685284.
      View in: PubMed
    25. de Almeida SM, de Pereira AP, Pedroso MLA, Ribeiro CE, Rotta I, Tang B, Umlauf A, Franklin D, Saloner RG, Batista MGR, Letendre S, Heaton RK, Ellis RJ, Cherner M. Neurocognitive impairment with hepatitis C and HIV co-infection in Southern Brazil. J Neurovirol. 2018 Jun; 24(3):339-349. PMID: 29516346.
      View in: PubMed
    26. de Almeida SM, Ribeiro CE, Rotta I, Piovesan M, Tang B, Vaida F, Raboni SM, Letendre S, Potter M, Batistela Fernandes MS, Ellis RJ. Biomarkers of neuronal injury and amyloid metabolism in the cerebrospinal fluid of patients infected with HIV-1 subtypes B and C. J Neurovirol. 2018 Feb; 24(1):28-40. PMID: 29063514.
      View in: PubMed
    27. Marquine MJ, Heaton A, Johnson N, Rivera-Mindt M, Cherner M, Bloss C, Hulgan T, Umlauf A, Moore DJ, Fazeli P, Morgello S, Franklin D, Letendre S, Ellis R, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Simpson D, McCutchan JA, Grant I, Heaton RK. Differences in Neurocognitive Impairment Among HIV-Infected Latinos in the United States. J Int Neuropsychol Soc. 2018 Feb; 24(2):163-175. PMID: 28874213.
      View in: PubMed
    28. Yuen T, Brouillette MJ, Fellows LK, Ellis RJ, Letendre S, Heaton R, Mayo N. Personalized Risk Index for Neurocognitive Decline Among People With Well-Controlled HIV Infection. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):48-54. PMID: 28797021.
      View in: PubMed
    29. Coban H, Robertson K, Smurzynski M, Krishnan S, Wu K, Bosch RJ, Collier AC, Ellis RJ. Impact of aging on neurocognitive performance in previously antiretroviral-naive HIV-infected individuals on their first suppressive regimen. AIDS. 2017 07 17; 31(11):1565-1571. PMID: 28471765.
      View in: PubMed
    30. Johs NA, Wu K, Tassiopoulos K, Koletar SL, Kalayjian RC, Ellis RJ, Taiwo B, Palella FJ, Erlandson KM. Disability Among Middle-Aged and Older Persons With Human Immunodeficiency Virus Infection. Clin Infect Dis. 2017 Jul 01; 65(1):83-91. PMID: 28369402.
      View in: PubMed
    31. Yek C, Massanella M, Peling T, Lednovich K, Nair SV, Worlock A, Vargas M, Gianella S, Ellis RJ, Strain MC, Busch MP, Nugent CT, Richman DD. Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types. J Clin Microbiol. 2017 08; 55(8):2544-2553. PMID: 28592548.
      View in: PubMed
    32. Jia P, Zhao Z, Hulgan T, Bush WS, Samuels DC, Bloss CS, Heaton RK, Ellis RJ, Schork N, Marra CM, Collier AC, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, McCutchan JA, Barnholtz-Sloan JS, Franklin DR, Rosario D, Letendre SL, Grant I, Kallianpur AR. Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):413-426. PMID: 28447399.
      View in: PubMed
    33. Bryant AK, Moore DJ, Burdo TH, Lakritz JR, Gouaux B, Soontornniyomkij V, Achim CL, Masliah E, Grant I, Levine AJ, Ellis RJ. Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection. AIDS. 2017 04 24; 31(7):973-979. PMID: 28244955.
      View in: PubMed
    34. Patton SM, Wang Q, Hulgan T, Connor JR, Jia P, Zhao Z, Letendre SL, Ellis RJ, Bush WS, Samuels DC, Franklin DR, Kaur H, Iudicello J, Grant I, Kallianpur AR. Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults. Fluids Barriers CNS. 2017 Apr 21; 14(1):11. PMID: 28427421.
      View in: PubMed
    35. Mehta SR, Pérez-Santiago J, Hulgan T, Day TR, Barnholtz-Sloan J, Gittleman H, Letendre S, Ellis R, Heaton R, Patton S, Suben JD, Franklin D, Rosario D, Clifford DB, Collier AC, Marra CM, Gelman BB, McArthur J, McCutchan A, Morgello S, Simpson D, Connor J, Grant I, Kallianpur A. Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment. J Neuroinflammation. 2017 03 31; 14(1):72. PMID: 28359324.
      View in: PubMed
    36. Montoya JL, Iudicello J, Oppenheim HA, Fazeli PL, Potter M, Ma Q, Mills PJ, Ellis RJ, Grant I, Letendre SL, Moore DJ. Coagulation imbalance and neurocognitive functioning in older HIV-positive adults on suppressive antiretroviral therapy. AIDS. 2017 03 27; 31(6):787-795. PMID: 28099190.
      View in: PubMed
    37. Erlandson KM, Wu K, Koletar SL, Kalayjian RC, Ellis RJ, Taiwo B, Palella FJ, Tassiopoulos K. Association Between Frailty and Components of the Frailty Phenotype With Modifiable Risk Factors and Antiretroviral Therapy. J Infect Dis. 2017 03 15; 215(6):933-937. PMID: 28453849.
      View in: PubMed
    38. Sakoda ME, Fazeli PL, Ellis RJ, Jeste DV, Grant I, Letendre SL, Moore DJ. Higher Cystatin C Levels Are Associated With Neurocognitive Impairment in Older HIV+ Adults. J Acquir Immune Defic Syndr. 2017 Mar 01; 74(3):243-249. PMID: 27861242.
      View in: PubMed
    39. Keltner JR, Connolly CG, Vaida F, Jenkinson M, Fennema-Notestine C, Archibald S, Akkari C, Schlein A, Lee J, Wang D, Kim S, Li H, Rennels A, Miller DJ, Kesidis G, Franklin DR, Sanders C, Corkran S, Grant I, Brown GG, Atkinson JH, Ellis RJ. HIV Distal Neuropathic Pain Is Associated with Smaller Ventral Posterior Cingulate Cortex. Pain Med. 2017 03 01; 18(3):428-440. PMID: 27497320.
      View in: PubMed
    40. de Almeida SM, Kamat R, Cherner M, Umlauf A, Ribeiro CE, de Pereira AP, Franklin D, Heaton RK, Ellis RJ. Improving Detection of HIV-Associated Cognitive Impairment: Comparison of the International HIV Dementia Scale and a Brief Screening Battery. J Acquir Immune Defic Syndr. 2017 03 01; 74(3):332-338. PMID: 27828876.
      View in: PubMed
    41. de Almeida SM, Rotta I, Ribeiro CE, Oliveira MF, Chaillon A, de Pereira AP, Cunha AP, Zonta M, Bents JF, Raboni SM, Smith D, Letendre S, Ellis RJ. Dynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization-case study. J Neurovirol. 2017 06; 23(3):460-473. PMID: 28247269.
      View in: PubMed
    42. Montoya JL, Iudicello J, Fazeli PL, Hong S, Potter M, Ellis RJ, Grant I, Letendre SL, Moore DJ. Elevated Markers of Vascular Remodeling and Arterial Stiffness Are Associated With Neurocognitive Function in Older HIV+ Adults on Suppressive Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2017 Feb 01; 74(2):134-141. PMID: 27828873.
      View in: PubMed
    43. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 01; 13(1):e1006112. PMID: 28046096.
      View in: PubMed
    44. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 01 02; 31(1):1-4. PMID: 27755112.
      View in: PubMed
    45. de Almeida SM, Rotta I, Ribeiro CE, Smith D, Wang R, Judicello J, Potter M, Vaida F, Letendre S, Ellis RJ. Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection. J Neuroimmunol. 2016 12 15; 301:41-48. PMID: 27836178.
      View in: PubMed
    46. Bharti AR, McCutchan A, Deutsch R, Smith DM, Ellis RJ, Cherner M, Woods SP, Heaton RK, Grant I, Letendre SL. Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults. Clin Infect Dis. 2016 Dec 15; 63(12):1655-1660. PMID: 27794019.
      View in: PubMed
    47. Anderson AM, Muñoz-Moreno JA, McClernon DR, Ellis RJ, Cookson D, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Franklin DR, Heaton RK, Grant I, Letendre SL. Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy. J Infect Dis. 2017 Jan 01; 215(1):105-113. PMID: 27789723.
      View in: PubMed
    48. Keegan MR, Chittiprol S, Letendre SL, Winston A, Fuchs D, Boasso A, Iudicello J, Ellis RJ. Tryptophan Metabolism and Its Relationship with Depression and Cognitive Impairment Among HIV-infected Individuals. Int J Tryptophan Res. 2016; 9:79-88. PMID: 27812290.
      View in: PubMed
    49. Samuels DC, Kallianpur AR, Ellis RJ, Bush WS, Letendre S, Franklin D, Grant I, Hulgan T. European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection. Pathog Immun. 2016 Fall-Winter; 1(2):330-351. PMID: 28317034.
      View in: PubMed
    50. Obermeit LC, Beltran J, Casaletto KB, Franklin DR, Letendre S, Ellis R, Fennema-Notestine C, Vaida F, Collier AC, Marra CM, Clifford D, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Grant I, Heaton RK. Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining "symptomatic" versus "asymptomatic" HAND. J Neurovirol. 2017 02; 23(1):67-78. PMID: 27557777.
      View in: PubMed
    51. Gianella S, Kosakovsky Pond SL, Oliveira MF, Scheffler K, Strain MC, De la Torre A, Letendre S, Smith DM, Ellis RJ. Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy. Virus Evol. 2016 Jul; 2(2):vew020. PMID: 27774305.
      View in: PubMed
    52. de Almeida SM, Barbosa FJ, Kamat R, de Pereira AP, Raboni SM, Rotta I, Ribeiro CE, Cherner M, Ellis RJ, Atkinson JH. Suicide risk and prevalence of major depressive disorder (MDD) among individuals infected with HIV-1 subtype C versus B in Southern Brazil. J Neurovirol. 2016 12; 22(6):789-798. PMID: 27431676.
      View in: PubMed
    53. de Almeida SM, Rotta I, Jiang Y, Li X, Raboni SM, Ribeiro CE, Smith D, Potter M, Vaida F, Letendre S, Ellis RJ. Biomarkers of chemotaxis and inflammation in cerebrospinal fluid and serum in individuals with HIV-1 subtype C versus B. J Neurovirol. 2016 12; 22(6):715-724. PMID: 27400932.
      View in: PubMed
    54. Ellis R, Letendre SL. Update and New Directions in Therapeutics for Neurological Complications of HIV Infections. Neurotherapeutics. 2016 07; 13(3):471-6. PMID: 27383150; PMCID: PMC4965416 [Available on 07/01/17].
      View in: PubMed, PubMed Central
    55. Marquine MJ, Montoya JL, Umlauf A, Fazeli PL, Gouaux B, Heaton RK, Ellis RJ, Letendre SL, Grant I, Moore DJ. The Veterans Aging Cohort Study (VACS) Index and Neurocognitive Change: A Longitudinal Study. Clin Infect Dis. 2016 Sep 01; 63(5):694-702. PMID: 27199461; PMCID: PMC4981756 [Available on 09/01/17].
      View in: PubMed, PubMed Central
    56. Bharti AR, Woods SP, Ellis RJ, Cherner M, Rosario D, Potter M, Heaton RK, Everall IP, Masliah E, Grant I, Letendre SL. Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. HIV AIDS (Auckl). 2016; 8:93-9. PMID: 27199571; PMCID: PMC4857802.
      View in: PubMed, PubMed Central
    57. Cooley SA, Paul RH, Fennema-Notestine C, Morgan EE, Vaida F, Deng Q, Chen JA, Letendre S, Ellis R, Clifford DB, Marra CM, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Morgello S, Grant I, Ances BM. Apolipoprotein E e4 genotype status is not associated with neuroimaging outcomes in a large cohort of HIV+ individuals. J Neurovirol. 2016 10; 22(5):607-614. PMID: 27021072.
      View in: PubMed
    58. Hoenigl M, de Oliveira MF, Pérez-Santiago J, Zhang Y, Morris S, McCutchan AJ, Finkelman M, Marcotte TD, Ellis RJ, Gianella S. (1?3)-ß-D-Glucan Levels Correlate With Neurocognitive Functioning in HIV-Infected Persons on Suppressive Antiretroviral Therapy: A Cohort Study. Medicine (Baltimore). 2016 Mar; 95(11):e3162. PMID: 26986173.
      View in: PubMed
    59. de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. Corrigendum: Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2016 Jan 19; 6:19387. PMID: 26783252.
      View in: PubMed
    60. Hammond ER, Crum RM, Treisman GJ, Mehta SH, Clifford DB, Ellis RJ, Gelman BB, Grant I, Letendre SL, Marra CM, Morgello S, Simpson DM, Mcarthur JC. Persistent CSF but not plasma HIV RNA is associated with increased risk of new-onset moderate-to-severe depressive symptoms; a prospective cohort study. J Neurovirol. 2016 08; 22(4):479-87. PMID: 26727907.
      View in: PubMed
    61. Kallianpur AR, Wang Q, Jia P, Hulgan T, Zhao Z, Letendre SL, Ellis RJ, Heaton RK, Franklin DR, Barnholtz-Sloan J, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I. Anemia and Red Blood Cell Indices Predict HIV-Associated Neurocognitive Impairment in the Highly Active Antiretroviral Therapy Era. J Infect Dis. 2016 Apr 01; 213(7):1065-73. PMID: 26690344; PMCID: PMC4779306 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    62. Bryant AK, Fazeli PL, Letendre SL, Ellis RJ, Potter M, Burdo TH, Singh KK, Jeste DV, Grant I, Moore DJ. Complement Component 3 Is Associated with Metabolic Comorbidities in Older HIV-Positive Adults. AIDS Res Hum Retroviruses. 2016 Mar; 32(3):271-8. PMID: 26499082; PMCID: PMC4779974 [Available on 03/01/17].
      View in: PubMed, PubMed Central
    63. de Oliveira MF, Murrell B, Murrel B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S. Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART. Sci Rep. 2015 Nov 25; 5:17094. PMID: 26603568; PMCID: PMC4658529.
      View in: PubMed, PubMed Central
    64. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy AN, Ellis RJ, Letendre S, Grant I, Masliah E. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 Feb; 86:154-69. PMID: 26611103; PMCID: PMC4713337.
      View in: PubMed, PubMed Central
    65. de Oliveira MF, Gianella S, Letendre S, Scheffler K, Kosakovsky Pond SL, Smith DM, Strain M, Ellis RJ. Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR. PLoS One. 2015; 10(10):e0139510. PMID: 26431315.
      View in: PubMed
    66. Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TR, Ramirez-Gaona M, Suben JD, Murrell B, Massanella M, Cherner M, Smith DM, Ellis RJ, Letendre SL, Mehta SR. Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection. J Neurovirol. 2016 Apr; 22(2):191-200. PMID: 26428514; PMCID: PMC4862614 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    67. Andreae MH, Carter GM, Shaparin N, Suslov K, Ellis RJ, Ware MA, Abrams DI, Prasad H, Wilsey B, Indyk D, Johnson M, Sacks HS. Inhaled Cannabis for Chronic Neuropathic Pain: A Meta-analysis of Individual Patient Data. J Pain. 2015 Dec; 16(12):1221-1232. PMID: 26362106.
      View in: PubMed
    68. Hulgan T, Samuels DC, Bush W, Ellis RJ, Letendre SL, Heaton RK, Franklin DR, Straub P, Murdock DG, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Grant I, Kallianpur AR. Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection. Clin Infect Dis. 2015 Nov 01; 61(9):1476-84. PMID: 26129753; PMCID: PMC4599391 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    69. Lalazar G, Mizrahi M, Turgeman I, Adar T, Ben Ya'acov A, Shabat Y, Nimer A, Hemed N, Zolotarovya L, Lichtenstein Y, Lisovoder N, Samira S, Shalit I, Ellis R, Ilan Y. Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial. J Clin Immunol. 2015 May; 35(4):399-407. PMID: 25876706.
      View in: PubMed
    70. Malvar J, Vaida F, Sanders CF, Atkinson JH, Bohannon W, Keltner J, Robinson-Papp J, Simpson DM, Marra CM, Clifford DB, Gelman B, Fan J, Grant I, Ellis RJ. Predictors of new-onset distal neuropathic pain in HIV-infected individuals in the era of combination antiretroviral therapy. Pain. 2015 Apr; 156(4):731-9. PMID: 25659067.
      View in: PubMed
    71. Ipser JC, Brown GG, Bischoff-Grethe A, Connolly CG, Ellis RJ, Heaton RK, Grant I. HIV infection is associated with attenuated frontostriatal intrinsic connectivity: a preliminary study. J Int Neuropsychol Soc. 2015 Mar; 21(3):203-13. PMID: 25824201; PMCID: PMC4400233.
      View in: PubMed, PubMed Central
    72. Sattler FR, He J, Letendre S, Wilson C, Sanders C, Heaton R, Ellis R, Franklin D, Aldrovandi G, Marra CM, Clifford D, Morgello S, Grant I, McCutchan JA. Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation. J Acquir Immune Defic Syndr. 2015 Mar 01; 68(3):281-8. PMID: 25469522.
      View in: PubMed
    73. Schrier RD, Hong S, Crescini M, Ellis R, Pérez-Santiago J, Spina C, Letendre S. Cerebrospinal fluid (CSF) CD8+ T-cells that express interferon-gamma contribute to HIV associated neurocognitive disorders (HAND). PLoS One. 2015; 10(2):e0116526. PMID: 25719800.
      View in: PubMed
    74. Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I. Reply to Haddow et al. Clin Infect Dis. 2015 May 01; 60(9):1442-3. PMID: 25645217; PMCID: PMC4415055.
      View in: PubMed, PubMed Central
    75. Bryant AK, Ellis RJ, Umlauf A, Gouaux B, Soontornniyomkij V, Letendre SL, Achim CL, Masliah E, Grant I, Moore DJ. Antiretroviral therapy reduces neurodegeneration in HIV infection. AIDS. 2015 Jan 28; 29(3):323-30. PMID: 25686681; PMCID: PMC4353640.
      View in: PubMed, PubMed Central
    76. Kamat R, Cattie JE, Marcotte TD, Woods SP, Franklin DR, Corkran SH, Ellis RJ, Grant I, Heaton RK. Incident major depressive episodes increase the severity and risk of apathy in HIV infection. J Affect Disord. 2015 Apr 01; 175:475-80. PMID: 25679203; PMCID: PMC4386921.
      View in: PubMed, PubMed Central
    77. Heaton RK, Franklin DR, Deutsch R, Letendre S, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst AC, Fennema-Notestine C, Smith DM, Grant I. Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study. Clin Infect Dis. 2015 Feb 01; 60(3):473-80. PMID: 25362201; PMCID: PMC4303775.
      View in: PubMed, PubMed Central
    78. Connolly CG, Bischoff-Grethe A, Jordan SJ, Woods SP, Ellis RJ, Paulus MP, Grant I. Altered functional response to risky choice in HIV infection. PLoS One. 2014; 9(10):e111583. PMID: 25347679; PMCID: PMC4210250.
      View in: PubMed, PubMed Central
    79. Kamat R, Brown GG, Bolden K, Fennema-Notestein C, Archibald S, Marcotte TD, Letendre SL, Ellis RJ, Woods SP, Grant I, Heaton RK. Apathy is associated with white matter abnormalities in anterior, medial brain regions in persons with HIV infection. J Clin Exp Neuropsychol. 2014; 36(8):854-66. PMID: 25275424; PMCID: PMC4303236.
      View in: PubMed, PubMed Central
    80. Ene L, Franklin DR, Burlacu R, Luca AE, Blaglosov AG, Ellis RJ, Alexander TJ, Umlauf A, Grant I, Duiculescu DC, Achim CL, Marcotte TD. Neurocognitive functioning in a Romanian cohort of young adults with parenterally-acquired HIV-infection during childhood. J Neurovirol. 2014 Oct; 20(5):496-504. PMID: 25185868; PMCID: PMC4324616.
      View in: PubMed, PubMed Central
    81. Kallianpur AR, Jia P, Ellis RJ, Zhao Z, Bloss C, Wen W, Marra CM, Hulgan T, Simpson DM, Morgello S, McArthur JC, Clifford DB, Collier AC, Gelman BB, McCutchan JA, Franklin D, Samuels DC, Rosario D, Holzinger E, Murdock DG, Letendre S, Grant I. Genetic variation in iron metabolism is associated with neuropathic pain and pain severity in HIV-infected patients on antiretroviral therapy. PLoS One. 2014; 9(8):e103123. PMID: 25144566; PMCID: PMC4140681.
      View in: PubMed, PubMed Central
    82. Rotta I, Raboni SM, Ribeiro CE, Riedel M, Winhescki Mda G, Smith DM, Ellis RJ, de Almeida SM. Cerebrospinal fluid can be used for HIV genotyping when it fails in blood. Arq Neuropsiquiatr. 2014 Jul; 72(7):506-9. PMID: 25054982; PMCID: PMC4139176.
      View in: PubMed, PubMed Central
    83. Almeida SM, Marquie-Beck J, Bhatt A, Letendre S, McCutchan A, Ellis R. Portable lactate analyzer for measuring lactate in cerebrospinal fluid (CSF) and plasma - method-comparison evaluations. Arq Neuropsiquiatr. 2014 Jul; 72(7):500-5. PMID: 25054981; PMCID: PMC4259897.
      View in: PubMed, PubMed Central
    84. Hammond ER, Crum RM, Treisman GJ, Mehta SH, Marra CM, Clifford DB, Morgello S, Simpson DM, Gelman BB, Ellis RJ, Grant I, Letendre SL, McArthur JC. The cerebrospinal fluid HIV risk score for assessing central nervous system activity in persons with HIV. Am J Epidemiol. 2014 Aug 01; 180(3):297-307. PMID: 24966216.
      View in: PubMed
    85. Andrade RM, Torriani FJ, Ellis RJ. Acute HIV infection presenting as fulminant meningoencephalitis with massive CSF viral replication. Neurol Clin Pract. 2014 Jun; 4(3):256-259. PMID: 25110623.
      View in: PubMed
    86. Soontornniyomkij V, Umlauf A, Chung SA, Cochran ML, Soontornniyomkij B, Gouaux B, Toperoff W, Moore DJ, Masliah E, Ellis RJ, Grant I, Achim CL. HIV protease inhibitor exposure predicts cerebral small vessel disease. AIDS. 2014 Jun 01; 28(9):1297-306. PMID: 24637542; PMCID: PMC4071161.
      View in: PubMed, PubMed Central
    87. Adiga R, Ozdemir AY, Carides A, Wasilewski M, Yen W, Chitturi P, Ellis R, Langford D. Changes in PINCH levels in the CSF of HIV+ individuals correlate with hpTau and CD4 count. J Neurovirol. 2014 Aug; 20(4):371-9. PMID: 24817145; PMCID: PMC4104596.
      View in: PubMed, PubMed Central
    88. Grant I, Franklin DR, Deutsch R, Woods SP, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Heaton RK. Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology. 2014 Jun 10; 82(23):2055-62. PMID: 24814848; PMCID: PMC4118496.
      View in: PubMed, PubMed Central
    89. Ferrara M, Umlauf A, Sanders C, Meyer JM, Allen McCutchan J, Duarte N, Hampton Atkinson J, Grant I, Ellis RJ. The concomitant use of second-generation antipsychotics and long-term antiretroviral therapy may be associated with increased cardiovascular risk. Psychiatry Res. 2014 Aug 15; 218(1-2):201-8. PMID: 24794030; PMCID: PMC4082695.
      View in: PubMed, PubMed Central
    90. Cañizares S, Cherner M, Ellis RJ. HIV and aging: effects on the central nervous system. Semin Neurol. 2014 Feb; 34(1):27-34. PMID: 24715486; PMCID: PMC4296735.
      View in: PubMed, PubMed Central
    91. Keltner JR, Fennema-Notestine C, Vaida F, Wang D, Franklin DR, Dworkin RH, Sanders C, McCutchan JA, Archibald SL, Miller DJ, Kesidis G, Cushman C, Kim SM, Abramson I, Taylor MJ, Theilmann RJ, Julaton MD, Notestine RJ, Corkran S, Cherner M, Duarte NA, Alexander T, Robinson-Papp J, Gelman BB, Simpson DM, Collier AC, Marra CM, Morgello S, Brown G, Grant I, Atkinson JH, Jernigan TL, Ellis RJ. HIV-associated distal neuropathic pain is associated with smaller total cerebral cortical gray matter. J Neurovirol. 2014 Jun; 20(3):209-18. PMID: 24549970; PMCID: PMC4040150.
      View in: PubMed, PubMed Central
    92. Marquine MJ, Umlauf A, Rooney AS, Fazeli PL, Gouaux BD, Paul Woods S, Letendre SL, Ellis RJ, Grant I, Moore DJ. The veterans aging cohort study index is associated with concurrent risk for neurocognitive impairment. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):190-7. PMID: 24442225; PMCID: PMC3907119.
      View in: PubMed, PubMed Central
    93. Ellis RJ, Letendre S, Vaida F, Haubrich R, Heaton RK, Sacktor N, Clifford DB, Best BM, May S, Umlauf A, Cherner M, Sanders C, Ballard C, Simpson DM, Jay C, McCutchan JA. Randomized trial of central nervous system-targeted antiretrovirals for HIV-associated neurocognitive disorder. Clin Infect Dis. 2014 Apr; 58(7):1015-22. PMID: 24352352.
      View in: PubMed
    94. Chen H, Clifford DB, Deng L, Wu K, Lee AJ, Bosch RJ, Riddler SA, Ellis RJ, Evans SR. Peripheral neuropathy in ART-experienced patients: prevalence and risk factors. J Neurovirol. 2013 Dec; 19(6):557-64. PMID: 24297499; PMCID: PMC3965352.
      View in: PubMed, PubMed Central
    95. Fields J, Dumaop W, Adame A, Ellis RJ, Letendre S, Grant I, Masliah E. Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders. J Neuroimmune Pharmacol. 2013 Dec; 8(5):1197-209. PMID: 24292993; PMCID: PMC3973444.
      View in: PubMed, PubMed Central
    96. de Almeida SM, Ribeiro CE, de Pereira AP, Badiee J, Cherner M, Smith D, Maich I, Raboni SM, Rotta I, Barbosa FJ, Heaton RK, Umlauf A, Ellis RJ. Neurocognitive impairment in HIV-1 clade C- versus B-infected individuals in Southern Brazil. J Neurovirol. 2013 Dec; 19(6):550-6. PMID: 24277437.
      View in: PubMed
    97. Marquine MJ, Iudicello JE, Morgan EE, Brown GG, Letendre SL, Ellis RJ, Deutsch R, Woods SP, Grant I, Heaton RK. "Frontal systems" behaviors in comorbid human immunodeficiency virus infection and methamphetamine dependency. Psychiatry Res. 2014 Jan 30; 215(1):208-16. PMID: 24290100; PMCID: PMC3967865.
      View in: PubMed, PubMed Central
    98. Dufour CA, Marquine MJ, Fazeli PL, Henry BL, Ellis RJ, Grant I, Moore DJ. Physical exercise is associated with less neurocognitive impairment among HIV-infected adults. J Neurovirol. 2013 Oct; 19(5):410-7. PMID: 23934585; PMCID: PMC3795938.
      View in: PubMed, PubMed Central
    99. Fennema-Notestine C, Ellis RJ, Archibald SL, Jernigan TL, Letendre SL, Notestine RJ, Taylor MJ, Theilmann RJ, Julaton MD, Croteau DJ, Wolfson T, Heaton RK, Gamst AC, Franklin DR, Clifford DB, Collier AC, Gelman BB, Marra C, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Grant I. Increases in brain white matter abnormalities and subcortical gray matter are linked to CD4 recovery in HIV infection. J Neurovirol. 2013 Aug; 19(4):393-401. PMID: 23838849; PMCID: PMC3776609.
      View in: PubMed, PubMed Central
    100. Blackstone K, Iudicello JE, Morgan EE, Weber E, Moore DJ, Franklin DR, Ellis RJ, Grant I, Woods SP. Human immunodeficiency virus infection heightens concurrent risk of functional dependence in persons with long-term methamphetamine use. J Addict Med. 2013 Jul-Aug; 7(4):255-63. PMID: 23648641; PMCID: PMC3737384.
      View in: PubMed, PubMed Central
    101. Burdo TH, Weiffenbach A, Woods SP, Letendre S, Ellis RJ, Williams KC. Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection. AIDS. 2013 Jun 01; 27(9):1387-95. PMID: 23435298; PMCID: PMC3844286.
      View in: PubMed, PubMed Central
    102. Desplats P, Dumaop W, Smith D, Adame A, Everall I, Letendre S, Ellis R, Cherner M, Grant I, Masliah E. Molecular and pathologic insights from latent HIV-1 infection in the human brain. Neurology. 2013 Apr 09; 80(15):1415-23. PMID: 23486877; PMCID: PMC3662272.
      View in: PubMed, PubMed Central
    103. Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, Robertson K, Royal W, Sacktor N, Sithinamsuwan P, Smith DM, Valcour V, Wigdahl B, Wood C. Global NeuroAIDS roundtable. J Neurovirol. 2013 Feb; 19(1):1-9. PMID: 23354550; PMCID: PMC3713197.
      View in: PubMed, PubMed Central
    104. Fields J, Dumaop W, Rockenstein E, Mante M, Spencer B, Grant I, Ellis R, Letendre S, Patrick C, Adame A, Masliah E. Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer. J Neurovirol. 2013 Feb; 19(1):89-101. PMID: 23341224; PMCID: PMC3567331.
      View in: PubMed, PubMed Central
    105. Nguyen A, Rossi S, Croteau D, Best BM, Clifford D, Collier AC, Gelman B, Marra C, McArthur J, McCutchan JA, Morgello S, Simpson D, Ellis RJ, Grant I, Capparelli E, Letendre S. Etravirine in CSF is highly protein bound. J Antimicrob Chemother. 2013 May; 68(5):1161-8. PMID: 23335197; PMCID: PMC3625433.
      View in: PubMed, PubMed Central
    106. Sakamoto M, Marcotte TD, Umlauf A, Franklin D, Heaton RK, Ellis RJ, Letendre S, Alexander T, McCutchan JA, Morgan EE, Woods SP, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson D, Grant I. Concurrent classification accuracy of the HIV dementia scale for HIV-associated neurocognitive disorders in the CHARTER Cohort. J Acquir Immune Defic Syndr. 2013 Jan 01; 62(1):36-42. PMID: 23111573; PMCID: PMC3529802.
      View in: PubMed, PubMed Central
    107. Rodriguez-Penney AT, Iudicello JE, Riggs PK, Doyle K, Ellis RJ, Letendre SL, Grant I, Woods SP. Co-morbidities in persons infected with HIV: increased burden with older age and negative effects on health-related quality of life. AIDS Patient Care STDS. 2013 Jan; 27(1):5-16. PMID: 23305257; PMCID: PMC3545369.
      View in: PubMed, PubMed Central
    108. Weber E, Morgan EE, Iudicello JE, Blackstone K, Grant I, Ellis RJ, Letendre SL, Little S, Morris S, Smith DM, Moore DJ, Woods SP. Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection. J Neurovirol. 2013 Feb; 19(1):65-74. PMID: 23250704.
      View in: PubMed
    109. Kamat R, Morgan E, Marcotte TD, Badiee J, Maich I, Cherner M, de Almeida S, de Pereira AP, Ribeiro CE, Barbosa F, Atkinson JH, Ellis R. Implications of apathy and depression for everyday functioning in HIV/AIDS in Brazil. J Affect Disord. 2013 Sep 25; 150(3):1069-75. PMID: 23245465.
      View in: PubMed
    110. Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S. Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration. J Antimicrob Chemother. 2013 Mar; 68(3):684-9. PMID: 23143899; PMCID: PMC3566670.
      View in: PubMed, PubMed Central
    111. Morgan EE, Iudicello JE, Weber E, Duarte NA, Riggs PK, Delano-Wood L, Ellis R, Grant I, Woods SP. Synergistic effects of HIV infection and older age on daily functioning. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):341-8. PMID: 22878422.
      View in: PubMed
    112. Moore DJ, Posada C, Parikh M, Arce M, Vaida F, Riggs PK, Gouaux B, Ellis RJ, Letendre SL, Grant I, Atkinson JH. HIV-infected individuals with co-occurring bipolar disorder evidence poor antiretroviral and psychiatric medication adherence. AIDS Behav. 2012 Nov; 16(8):2257-66. PMID: 22041931; PMCID: PMC3351543.
      View in: PubMed, PubMed Central
    113. Holzinger ER, Hulgan T, Ellis RJ, Samuels DC, Ritchie MD, Haas DW, Kallianpur AR, Bloss CS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Franklin DR, Rosario D, Selph D, Letendre S, Grant I. Mitochondrial DNA variation and HIV-associated sensory neuropathy in CHARTER. J Neurovirol. 2012 Dec; 18(6):511-20. PMID: 23073667.
      View in: PubMed
    114. Hightower GK, Wong JK, Letendre SL, Umlauf AA, Ellis RJ, Ignacio CC, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment. Virology. 2012 Nov 25; 433(2):498-505. PMID: 22999095.
      View in: PubMed
    115. Evans SR, Lee AJ, Ellis RJ, Chen H, Wu K, Bosch RJ, Clifford DB. HIV peripheral neuropathy progression: protection with glucose-lowering drugs? J Neurovirol. 2012 Oct; 18(5):428-33. PMID: 22806348; PMCID: PMC3485691.
      View in: PubMed, PubMed Central
    116. Keltner JR, Vaida F, Ellis RJ, Moeller-Bertram T, Fitzsimmons C, Duarte NA, Robinson-Papp J, Dworkin RH, Clifford DB, McArthur JC, Simpson DM, Collier AC, Marra CM, Atkinson JH, Grant I. Health-related quality of life 'well-being' in HIV distal neuropathic pain is more strongly associated with depression severity than with pain intensity. Psychosomatics. 2012 Jul-Aug; 53(4):380-6. PMID: 22748751.
      View in: PubMed
    117. Kamat R, Woods SP, Marcotte TD, Ellis RJ, Grant I. Implications of apathy for everyday functioning outcomes in persons living with HIV infection. Arch Clin Neuropsychol. 2012 Aug; 27(5):520-31. PMID: 22705481; PMCID: PMC3399510.
      View in: PubMed, PubMed Central
    118. Moore DJ, Blackstone K, Woods SP, Ellis RJ, Atkinson JH, Heaton RK, Grant I. Methamphetamine use and neuropsychiatric factors are associated with antiretroviral non-adherence. AIDS Care. 2012; 24(12):1504-13. PMID: 22530794; PMCID: PMC3466384.
      View in: PubMed, PubMed Central
    119. Croteau D, Best BM, Letendre S, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S, Grant I. Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration. AIDS. 2012 Apr 24; 26(7):890-3. PMID: 22313954; PMCID: PMC3454507.
      View in: PubMed, PubMed Central
    120. Royal W, Cherner M, Carr J, Habib AG, Akomolafe A, Abimiku A, Charurat M, Farley J, Oluyemisi A, Mamadu I, Johnson J, Ellis R, McCutchan JA, McCutchen JA, Grant I, Blattner WA. Clinical features and preliminary studies of virological correlates of neurocognitive impairment among HIV-infected individuals in Nigeria. J Neurovirol. 2012 Jun; 18(3):191-9. PMID: 22528480; PMCID: PMC3717366.
      View in: PubMed, PubMed Central
    121. Choi JY, Hightower GK, Wong JK, Heaton R, Woods S, Grant I, Marcotte TD, Ellis RJ, Letendre SL, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Richman DD, Smith DM. Genetic features of cerebrospinal fluid-derived subtype B HIV-1 tat. J Neurovirol. 2012 Apr; 18(2):81-90. PMID: 22528397.
      View in: PubMed
    122. Best BM, Letendre SL, Koopmans P, Rossi SS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Capparelli EV, Ellis RJ, Grant I. Low cerebrospinal fluid concentrations of the nucleotide HIV reverse transcriptase inhibitor, tenofovir. J Acquir Immune Defic Syndr. 2012 Apr 01; 59(4):376-81. PMID: 22217676.
      View in: PubMed
    123. Pottiez G, Jagadish T, Yu F, Letendre S, Ellis R, Duarte NA, Grant I, Gendelman HE, Fox HS, Ciborowski P. Plasma proteomic profiling in HIV-1 infected methamphetamine abusers. PLoS One. 2012; 7(2):e31031. PMID: 22359561; PMCID: PMC3281056.
      View in: PubMed, PubMed Central
    124. Croteau D, Letendre S, Best BM, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Way L, Capparelli E, Grant I. Therapeutic amprenavir concentrations in cerebrospinal fluid. Antimicrob Agents Chemother. 2012 Apr; 56(4):1985-9. PMID: 22290964; PMCID: PMC3318381.
      View in: PubMed, PubMed Central
    125. Riggs PK, Vaida F, Rossi SS, Sorkin LS, Gouaux B, Grant I, Ellis RJ. A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. Brain Res. 2012 Jan 11; 1431:46-52. PMID: 22133305.
      View in: PubMed
    126. Bharti AR, Letendre SL, Wolfson T, Clifford D, Collier AC, Gelman B, McArthur J, Marra C, McCutchan A, Morgello S, Simpson D, Ellis RJ, Grant I. Clinical variables identify seronegative HCV co-infection in HIV-infected individuals. J Clin Virol. 2011 Dec; 52(4):328-32. PMID: 21924674.
      View in: PubMed
    127. Ellis RJ, Badiee J, Vaida F, Letendre S, Heaton RK, Clifford D, Collier AC, Gelman B, McArthur J, Morgello S, McCutchan JA, Grant I. CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy. AIDS. 2011 Sep 10; 25(14):1747-51. PMID: 21750419.
      View in: PubMed
    128. de Almeida SM, Shumaker SD, LeBlanc SK, Delaney P, Marquie-Beck J, Ueland S, Alexander T, Ellis RJ. Incidence of post-dural puncture headache in research volunteers. Headache. 2011 Nov-Dec; 51(10):1503-10. PMID: 21797856; PMCID: PMC3217171.
      View in: PubMed, PubMed Central
    129. Scott JC, Woods SP, Vigil O, Heaton RK, Grant I, Ellis RJ, Marcotte TD. Script generation of activities of daily living in HIV-associated neurocognitive disorders. J Int Neuropsychol Soc. 2011 Jul; 17(4):740-5. PMID: 22882813; PMCID: PMC3419482.
      View in: PubMed, PubMed Central
    130. Scott JC, Woods SP, Vigil O, Heaton RK, Schweinsburg BC, Ellis RJ, Grant I, Marcotte TD. A neuropsychological investigation of multitasking in HIV infection: implications for everyday functioning. Neuropsychology. 2011 Jul; 25(4):511-9. PMID: 21401259; PMCID: PMC3125422.
      View in: PubMed, PubMed Central
    131. Burdo TH, Lentz MR, Autissier P, Krishnan A, Halpern E, Letendre S, Rosenberg ES, Ellis RJ, Williams KC. Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy. J Infect Dis. 2011 Jul 01; 204(1):154-63. PMID: 21628670; PMCID: PMC3105035.
      View in: PubMed, PubMed Central
    132. Paulino AD, Ubhi K, Rockenstein E, Adame A, Crews L, Letendre S, Ellis R, Everall IP, Grant I, Masliah E. Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling. J Neurovirol. 2011 Aug; 17(4):327-40. PMID: 21660601; PMCID: PMC3919659.
      View in: PubMed, PubMed Central
    133. Jernigan TL, Archibald SL, Fennema-Notestine C, Taylor MJ, Theilmann RJ, Julaton MD, Notestine RJ, Wolfson T, Letendre SL, Ellis RJ, Heaton RK, Gamst AC, Franklin DR, Clifford DB, Collier AC, Gelman BB, Marra C, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Grant I. Clinical factors related to brain structure in HIV: the CHARTER study. J Neurovirol. 2011 Jun; 17(3):248-57. PMID: 21544705; PMCID: PMC3702821.
      View in: PubMed, PubMed Central
    134. Evans SR, Ellis RJ, Chen H, Yeh TM, Lee AJ, Schifitto G, Wu K, Bosch RJ, McArthur JC, Simpson DM, Clifford DB. Peripheral neuropathy in HIV: prevalence and risk factors. AIDS. 2011 Apr 24; 25(7):919-28. PMID: 21330902; PMCID: PMC3196556.
      View in: PubMed, PubMed Central
    135. Gupta S, Bousman CA, Chana G, Cherner M, Heaton RK, Deutsch R, Ellis RJ, Grant I, Everall IP. Dopamine receptor D3 genetic polymorphism (rs6280TC) is associated with rates of cognitive impairment in methamphetamine-dependent men with HIV: preliminary findings. J Neurovirol. 2011 Jun; 17(3):239-47. PMID: 21491142; PMCID: PMC3151555.
      View in: PubMed, PubMed Central
    136. Ances BM, Vaida F, Cherner M, Yeh MJ, Liang CL, Gardner C, Grant I, Ellis RJ, Buxton RB. HIV and chronic methamphetamine dependence affect cerebral blood flow. J Neuroimmune Pharmacol. 2011 Sep; 6(3):409-19. PMID: 21431471; PMCID: PMC3251315.
      View in: PubMed, PubMed Central
    137. Cysique LA, Franklin D, Abramson I, Ellis RJ, Letendre S, Collier A, Clifford D, Gelman B, McArthur J, Morgello S, Simpson D, McCutchan JA, Grant I, Heaton RK. Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change. J Clin Exp Neuropsychol. 2011 Jun; 33(5):505-22. PMID: 21391011.
      View in: PubMed
    138. de Almeida SM, Boritza K, Cogo LL, Pessa L, França J, Rota I, Muro M, Ribeiro C, Raboni SM, Vidal LR, Nogueira MB, Ellis R. Quantification of cerebrospinal fluid lactic acid in the differential diagnosis between HIV chronic meningitis and opportunistic meningitis. Clin Chem Lab Med. 2011 May; 49(5):891-6. PMID: 21345043.
      View in: PubMed
    139. Smurzynski M, Wu K, Letendre S, Robertson K, Bosch RJ, Clifford DB, Evans S, Collier AC, Taylor M, Ellis R. Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS. 2011 Jan 28; 25(3):357-65. PMID: 21124201; PMCID: PMC3022370.
      View in: PubMed, PubMed Central
    140. Letendre SL, Zheng JC, Kaul M, Yiannoutsos CT, Ellis RJ, Taylor MJ, Marquie-Beck J, Navia B. Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals. J Neurovirol. 2011 Feb; 17(1):63-9. PMID: 21246320; PMCID: PMC3032187.
      View in: PubMed, PubMed Central
    141. Banerjee S, McCutchan JA, Ances BM, Deutsch R, Riggs PK, Way L, Ellis RJ. Hypertriglyceridemia in combination antiretroviral-treated HIV-positive individuals: potential impact on HIV sensory polyneuropathy. AIDS. 2011 Jan 14; 25(2):F1-6. PMID: 21150557; PMCID: PMC3729045.
      View in: PubMed, PubMed Central
    142. Lin K, Taylor MJ, Heaton R, Franklin D, Jernigan T, Fennema-Notestine C, McCutchan A, Atkinson JH, Ellis RJ, McArthur J, Morgello S, Simpson D, Collier AC, Marra C, Gelman B, Clifford D, Grant I. Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals. J Clin Exp Neuropsychol. 2011 Mar; 33(3):326-34. PMID: 21229435.
      View in: PubMed
    143. Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S, Corkran SH, Duarte NA, Clifford DB, Woods SP, Collier AC, Marra CM, Morgello S, Mindt MR, Taylor MJ, Marcotte TD, Atkinson JH, Wolfson T, Gelman BB, McArthur JC, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I. HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol. 2011 Feb; 17(1):3-16. PMID: 21174240.
      View in: PubMed
    144. Moore DJ, Letendre SL, Morris S, Umlauf A, Deutsch R, Smith DM, Little S, Rooney A, Franklin DR, Gouaux B, Leblanc S, Rosario D, Fennema-Notestine C, Heaton RK, Ellis RJ, Atkinson JH, Grant I. Neurocognitive functioning in acute or early HIV infection. J Neurovirol. 2011 Feb; 17(1):50-7. PMID: 21165782.
      View in: PubMed
    145. Raboni SM, Almeida SM, Rotta I, Ribeiro CE, Rosario D, Vidal LR, Nogueira MB, Riedel M, Winhescki Mda G, Ferreira KA, Ellis R. Molecular epidemiology of HIV-1 clades in Southern Brazil. Mem Inst Oswaldo Cruz. 2010 Dec; 105(8):1044-9. PMID: 21225203; PMCID: PMC3867634.
      View in: PubMed, PubMed Central
    146. Best BM, Koopmans PP, Letendre SL, Capparelli EV, Rossi SS, Clifford DB, Collier AC, Gelman BB, Mbeo G, McCutchan JA, Simpson DM, Haubrich R, Ellis R, Grant I. Efavirenz concentrations in CSF exceed IC50 for wild-type HIV. J Antimicrob Chemother. 2011 Feb; 66(2):354-7. PMID: 21098541; PMCID: PMC3019085.
      View in: PubMed, PubMed Central
    147. Ances B, Vaida F, Ellis R, Buxton R. Test-retest stability of calibrated BOLD-fMRI in HIV- and HIV+ subjects. Neuroimage. 2011 Feb 01; 54(3):2156-62. PMID: 20932922; PMCID: PMC3229916.
      View in: PubMed, PubMed Central
    148. Croteau D, Letendre S, Best BM, Ellis RJ, Breidinger S, Clifford D, Collier A, Gelman B, Marra C, Mbeo G, McCutchan A, Morgello S, Simpson D, Way L, Vaida F, Ueland S, Capparelli E, Grant I. Total raltegravir concentrations in cerebrospinal fluid exceed the 50-percent inhibitory concentration for wild-type HIV-1. Antimicrob Agents Chemother. 2010 Dec; 54(12):5156-60. PMID: 20876368; PMCID: PMC2981289.
      View in: PubMed, PubMed Central
    149. Kanmogne GD, Kuate CT, Cysique LA, Fonsah JY, Eta S, Doh R, Njamnshi DM, Nchindap E, Franklin DR, Ellis RJ, McCutchan JA, Binam F, Mbanya D, Heaton RK, Njamnshi AK. HIV-associated neurocognitive disorders in sub-Saharan Africa: a pilot study in Cameroon. BMC Neurol. 2010 Jul 13; 10:60. PMID: 20626870; PMCID: PMC2912842.
      View in: PubMed, PubMed Central
    150. Ellis RJ, Rosario D, Clifford DB, McArthur JC, Simpson D, Alexander T, Gelman BB, Vaida F, Collier A, Marra CM, Ances B, Atkinson JH, Dworkin RH, Morgello S, Grant I. Continued high prevalence and adverse clinical impact of human immunodeficiency virus-associated sensory neuropathy in the era of combination antiretroviral therapy: the CHARTER Study. Arch Neurol. 2010 May; 67(5):552-8. PMID: 20457954.
      View in: PubMed
    151. Letendre SL, Ellis RJ, Ances BM, McCutchan JA. Neurologic complications of HIV disease and their treatment. Top HIV Med. 2010 Apr-May; 18(2):45-55. PMID: 20516524.
      View in: PubMed
    152. de Almeida SM, Bhatt A, Riggs PK, Durelle J, Lazzaretto D, Marquie-Beck J, McCutchan A, Letendre S, Ellis R. Cerebrospinal fluid human immunodeficiency virus viral load in patients with neurosyphilis. J Neurovirol. 2010 Feb; 16(1):6-12. PMID: 20132081; PMCID: PMC3076453.
      View in: PubMed, PubMed Central
    153. Ances BM, Vaida F, Yeh MJ, Liang CL, Buxton RB, Letendre S, McCutchan JA, Ellis RJ. HIV infection and aging independently affect brain function as measured by functional magnetic resonance imaging. J Infect Dis. 2010 Feb 01; 201(3):336-40. PMID: 20047503; PMCID: PMC2804778.
      View in: PubMed, PubMed Central
    154. Zhao Y, Navia BA, Marra CM, Singer EJ, Chang L, Berger J, Ellis RJ, Kolson DL, Simpson D, Miller EN, Lipton SA, Evans SR, Schifitto G. Memantine for AIDS dementia complex: open-label report of ACTG 301. HIV Clin Trials. 2010 Jan-Feb; 11(1):59-67. PMID: 20400412; PMCID: PMC2981797.
      View in: PubMed, PubMed Central
    155. Ances BM, Vaida F, Rosario D, Marquie-Beck J, Ellis RJ, Simpson DM, Clifford DB, McArthur JC, Grant I, McCutchan JA. Role of metabolic syndrome components in HIV-associated sensory neuropathy. AIDS. 2009 Nov 13; 23(17):2317-22. PMID: 19823068; PMCID: PMC2896813.
      View in: PubMed, PubMed Central
    156. Ellis R. HIV and antiretroviral therapy: impact on the central nervous system. Prog Neurobiol. 2010 Jun; 91(2):185-7. PMID: 19857545; PMCID: PMC2860030.
      View in: PubMed, PubMed Central
    157. Hightower GK, Letendre SL, Cherner M, Gibson SA, Ellis RJ, Wolfson TJ, Gamst AC, Ignacio CC, Heaton RK, Grant I, Richman DD, Smith DM. Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance. Virology. 2009 Nov 25; 394(2):243-8. PMID: 19762060; PMCID: PMC3046809.
      View in: PubMed, PubMed Central
    158. Marra CM, Zhao Y, Clifford DB, Letendre S, Evans S, Henry K, Ellis RJ, Rodriguez B, Coombs RW, Schifitto G, McArthur JC, Robertson K. Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance. AIDS. 2009 Jul 17; 23(11):1359-66. PMID: 19424052; PMCID: PMC2706549.
      View in: PubMed, PubMed Central
    159. Harrington PR, Schnell G, Letendre SL, Ritola K, Robertson K, Hall C, Burch CL, Jabara CB, Moore DT, Ellis RJ, Price RW, Swanstrom R. Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course. AIDS. 2009 May 15; 23(8):907-15. PMID: 19414991; PMCID: PMC3089803.
      View in: PubMed, PubMed Central
    160. Ellis RJ, Calero P, Stockin MD. HIV infection and the central nervous system: a primer. Neuropsychol Rev. 2009 Jun; 19(2):144-51. PMID: 19415500; PMCID: PMC2690832.
      View in: PubMed, PubMed Central
    161. Ances BM, Bhatt A, Vaida F, Rosario D, Alexander T, Marquie-Beck J, Ellis RJ, Letendre S, Grant I, McCutchan JA. Role of metabolic syndrome components in human immunodeficiency virus-associated stroke. J Neurovirol. 2009 May; 15(3):249-56. PMID: 19562611; PMCID: PMC2891579.
      View in: PubMed, PubMed Central
    162. Pendyala G, Trauger SA, Kalisiak E, Ellis RJ, Siuzdak G, Fox HS. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys. J Proteome Res. 2009 May; 8(5):2253-60. PMID: 19281240; PMCID: PMC2682714.
      View in: PubMed, PubMed Central
    163. Gongvatana A, Schweinsburg BC, Taylor MJ, Theilmann RJ, Letendre SL, Alhassoon OM, Jacobus J, Woods SP, Jernigan TL, Ellis RJ, Frank LR, Grant I. White matter tract injury and cognitive impairment in human immunodeficiency virus-infected individuals. J Neurovirol. 2009 Apr; 15(2):187-95. PMID: 19306228.
      View in: PubMed
    164. Letendre SL, Ellis RJ, Everall I, Ances B, Bharti A, McCutchan JA. Neurologic complications of HIV disease and their treatment. Top HIV Med. 2009 Apr-May; 17(2):46-56. PMID: 19401607; PMCID: PMC3065886.
      View in: PubMed, PubMed Central
    165. Best BM, Letendre SL, Brigid E, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Ellis R, Capparelli EV, Grant I. Low atazanavir concentrations in cerebrospinal fluid. AIDS. 2009 Jan 02; 23(1):83-7. PMID: 19050389.
      View in: PubMed
    166. Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ. Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 2009 Mar 01; 385(1):204-8. PMID: 19100592; PMCID: PMC2794037.
      View in: PubMed, PubMed Central
    167. Childers ME, Woods SP, Letendre S, McCutchan JA, Rosario D, Grant I, Mindt MR, Ellis RJ. Cognitive functioning during highly active antiretroviral therapy interruption in human immunodeficiency virus type 1 infection. J Neurovirol. 2008 Nov; 14(6):550-7. PMID: 19016380; PMCID: PMC4692591.
      View in: PubMed, PubMed Central
    168. Ellis RJ, Marquie-Beck J, Delaney P, Alexander T, Clifford DB, McArthur JC, Simpson DM, Ake C, Collier AC, Gelman BB, McCutchan JA, Morgello S, Grant I. Human immunodeficiency virus protease inhibitors and risk for peripheral neuropathy. Ann Neurol. 2008 Nov; 64(5):566-72. PMID: 19067367.
      View in: PubMed
    169. Gopukumar K, Rao SL, Satishchandra P, Dasgupta J, Ellis RJ, Subbakrishna DK, Mariamma P, Kamat A, Desai A, Ravi V, Rao BS, Satish KS, Kumar M. Cognitive changes in asymptomatic drug-naïve human immunodeficiency virus type 1 clade C infection. J Neurovirol. 2008 Nov; 14(6):480-5. PMID: 19021075.
      View in: PubMed
    170. Burdo TH, Ellis RJ, Fox HS. Osteopontin is increased in HIV-associated dementia. J Infect Dis. 2008 Sep 01; 198(5):715-22. PMID: 18616394; PMCID: PMC2587027.
      View in: PubMed, PubMed Central
    171. Ellis RJ, Toperoff W, Vaida F, van den Brande G, Gonzales J, Gouaux B, Bentley H, Atkinson JH. Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Neuropsychopharmacology. 2009 Feb; 34(3):672-80. PMID: 18688212; PMCID: PMC3066045.
      View in: PubMed, PubMed Central
    172. Letendre S, McCutchan JA, Ellis RJ. Highlights of the 15th Conference on Retroviruses and Opportunistic Infections. Neurologic complications of HIV disease and their treatment. Top HIV Med. 2008 Apr-May; 16(1):15-22. PMID: 18441379.
      View in: PubMed
    173. Ances BM, Letendre SL, Alexander T, Ellis RJ. Role of psychiatric medications as adjunct therapy in the treatment of HIV associated neurocognitive disorders. Int Rev Psychiatry. 2008 Feb; 20(1):89-93. PMID: 18240065.
      View in: PubMed
    174. Letendre S, Marquie-Beck J, Capparelli E, Best B, Clifford D, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S, Simpson D, Grant I, Ellis RJ. Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol. 2008 Jan; 65(1):65-70. PMID: 18195140.
      View in: PubMed
    175. Atkinson JH, Heaton RK, Patterson TL, Wolfson T, Deutsch R, Brown SJ, Summers J, Sciolla A, Gutierrez R, Ellis RJ, Abramson I, Hesselink JR, McCutchan JA, Grant I. Two-year prospective study of major depressive disorder in HIV-infected men. J Affect Disord. 2008 Jun; 108(3):225-34. PMID: 18045694; PMCID: PMC2494949.
      View in: PubMed, PubMed Central
    176. Evans SR, Yeh TM, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Schifitto G. Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090. HIV Clin Trials. 2007 Nov-Dec; 8(6):437-46. PMID: 18042509.
      View in: PubMed
    177. Schifitto G, Navia BA, Yiannoutsos CT, Marra CM, Chang L, Ernst T, Jarvik JG, Miller EN, Singer EJ, Ellis RJ, Kolson DL, Simpson D, Nath A, Berger J, Shriver SL, Millar LL, Colquhoun D, Lenkinski R, Gonzalez RG, Lipton SA. Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS. 2007 Sep 12; 21(14):1877-86. PMID: 17721095.
      View in: PubMed
    178. Letendre S, Paulino AD, Rockenstein E, Adame A, Crews L, Cherner M, Heaton R, Ellis R, Everall IP, Grant I, Masliah E. Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV. J Infect Dis. 2007 Aug 01; 196(3):361-70. PMID: 17597450.
      View in: PubMed
    179. Gupta JD, Satishchandra P, Gopukumar K, Wilkie F, Waldrop-Valverde D, Ellis R, Ownby R, Subbakrishna DK, Desai A, Kamat A, Ravi V, Rao BS, Satish KS, Kumar M. Neuropsychological deficits in human immunodeficiency virus type 1 clade C-seropositive adults from South India. J Neurovirol. 2007 Jun; 13(3):195-202. PMID: 17613709.
      View in: PubMed
    180. McCutchan JA, Wu JW, Robertson K, Koletar SL, Ellis RJ, Cohn S, Taylor M, Woods S, Heaton R, Currier J, Williams PL. HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS. 2007 May 31; 21(9):1109-17. PMID: 17502721.
      View in: PubMed
    181. Morgan EE, Woods SP, Scott JC, Childers M, Beck JM, Ellis RJ, Grant I, Heaton RK. Predictive validity of demographically adjusted normative standards for the HIV Dementia Scale. J Clin Exp Neuropsychol. 2008 Jan; 30(1):83-90. PMID: 17852582.
      View in: PubMed
    182. Letendre S, Ances B, Gibson S, Ellis RJ. Neurologic complications of HIV disease and their treatment. Top HIV Med. 2007 Apr-May; 15(2):32-9. PMID: 17485785.
      View in: PubMed
    183. Ellis RJ, Joseph J, de Almeida SM. NeuroAIDS in Brazil. J Neurovirol. 2007 Apr; 13(2):89-96. PMID: 17505977.
      View in: PubMed
    184. Ellis RJ. Evidence-based treatment for HIV-associated dementia and cognitive impairment: why so little? PLoS Clin Trials. 2007 Mar 30; 2(3):e15. PMID: 17401455; PMCID: PMC1845157.
      View in: PubMed, PubMed Central
    185. Ances BM, Ellis RJ. Dementia and neurocognitive disorders due to HIV-1 infection. Semin Neurol. 2007 Feb; 27(1):86-92. PMID: 17226745.
      View in: PubMed
    186. May S, Letendre S, Haubrich R, McCutchan JA, Heaton R, Capparelli E, Ellis R. Meeting practical challenges of a trial involving a multitude of treatment regimens: an example of a multi-center randomized controlled clinical trial in neuroAIDS. J Neuroimmune Pharmacol. 2007 Mar; 2(1):97-104. PMID: 18040832.
      View in: PubMed
    187. Ellis RJ. Clinical trials in HIV CNS disease and treatment management. J Neuroimmune Pharmacol. 2007 Mar; 2(1):20-5. PMID: 18040822.
      View in: PubMed
    188. Letendre SL, Marquie-Beck J, Ellis RJ, Woods SP, Best B, Clifford DB, Collier AC, Gelman BB, Marra C, McArthur JC, McCutchan JA, Morgello S, Simpson D, Alexander TJ, Durelle J, Heaton R, Grant I. The role of cohort studies in drug development: clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the central nervous system. J Neuroimmune Pharmacol. 2007 Mar; 2(1):120-7. PMID: 18040835.
      View in: PubMed
    189. Cherner M, Cysique L, Heaton RK, Marcotte TD, Ellis RJ, Masliah E, Grant I. Neuropathologic confirmation of definitional criteria for human immunodeficiency virus-associated neurocognitive disorders. J Neurovirol. 2007; 13(1):23-8. PMID: 17454445.
      View in: PubMed
    190. Ellis R, Langford D, Masliah E. HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci. 2007 Jan; 8(1):33-44. PMID: 17180161.
      View in: PubMed
    191. Paul RH, Yiannoutsos CT, Miller EN, Chang L, Marra CM, Schifitto G, Ernst T, Singer E, Richards T, Jarvik GJ, Price R, Meyerhoff DJ, Kolson D, Ellis RJ, Gonzalez G, Lenkinski RE, Cohen RA, Navia BA. Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. J Neuropsychiatry Clin Neurosci. 2007; 19(3):283-92. PMID: 17827413.
      View in: PubMed
    192. Ances BM, Letendre S, Buzzell M, Marquie-Beck J, Lazaretto D, Marcotte TD, Grant I, Ellis RJ. Valproic acid does not affect markers of human immunodeficiency virus disease progression. J Neurovirol. 2006 Oct; 12(5):403-6. PMID: 17065134.
      View in: PubMed
    193. Letendre SL, Woods SP, Ellis RJ, Atkinson JH, Masliah E, van den Brande G, Durelle J, Grant I, Everall I. Lithium improves HIV-associated neurocognitive impairment. AIDS. 2006 Sep 11; 20(14):1885-8. PMID: 16954730.
      View in: PubMed
    194. Monteiro de Almeida S, Letendre S, Zimmerman J, Kolakowski S, Lazzaretto D, McCutchan JA, Ellis R. Relationship of CSF leukocytosis to compartmentalized changes in MCP-1/CCL2 in the CSF of HIV-infected patients undergoing interruption of antiretroviral therapy. J Neuroimmunol. 2006 Oct; 179(1-2):180-5. PMID: 16901548.
      View in: PubMed
    195. de Almeida SM, Letendre S, Ellis R. Human immunodeficiency virus and the central nervous system. Braz J Infect Dis. 2006 Feb; 10(1):41-50. PMID: 16767315.
      View in: PubMed
    196. Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain. 2006 Jul; 129(Pt 7):1872-83. PMID: 16735456.
      View in: PubMed
    197. Rossi S, Yaksh T, Bentley H, van den Brande G, Grant I, Ellis R. Characterization of interference with 6 commercial delta9-tetrahydrocannabinol immunoassays by efavirenz (glucuronide) in urine. Clin Chem. 2006 May; 52(5):896-7. PMID: 16638958.
      View in: PubMed
    198. Moore DJ, Masliah E, Rippeth JD, Gonzalez R, Carey CL, Cherner M, Ellis RJ, Achim CL, Marcotte TD, Heaton RK, Grant I. Cortical and subcortical neurodegeneration is associated with HIV neurocognitive impairment. AIDS. 2006 Apr 04; 20(6):879-87. PMID: 16549972.
      View in: PubMed
    199. Langford D, Marquie-Beck J, de Almeida S, Lazzaretto D, Letendre S, Grant I, McCutchan JA, Masliah E, Ellis RJ. Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patients. J Neurovirol. 2006 Apr; 12(2):100-7. PMID: 16798671.
      View in: PubMed
    200. Letendre S, Ellis RJ. Neurologic complications of HIV disease and their treatments. Top HIV Med. 2006 Mar-Apr; 14(1):21-6. PMID: 16641524.
      View in: PubMed
    201. Ellis RJ, Evans SR, Clifford DB, Moo LR, McArthur JC, Collier AC, Benson C, Bosch R, Simpson D, Yiannoutsos CT, Yang Y, Robertson K. Clinical validation of the NeuroScreen. J Neurovirol. 2005 Dec; 11(6):503-11. PMID: 16338744.
      View in: PubMed
    202. Letendre SL, Cherner M, Ellis RJ, Marquie-Beck J, Gragg B, Marcotte T, Heaton RK, McCutchan JA, Grant I. The effects of hepatitis C, HIV, and methamphetamine dependence on neuropsychological performance: biological correlates of disease. AIDS. 2005 Oct; 19 Suppl 3:S72-8. PMID: 16251831.
      View in: PubMed
    203. Monteiro de Almeida S, Letendre S, Zimmerman J, Lazzaretto D, McCutchan A, Ellis R. Dynamics of monocyte chemoattractant protein type one (MCP-1) and HIV viral load in human cerebrospinal fluid and plasma. J Neuroimmunol. 2005 Dec; 169(1-2):144-52. PMID: 16182380.
      View in: PubMed
    204. Woods SP, Childers M, Ellis RJ, Guaman S, Grant I, Heaton RK. A battery approach for measuring neuropsychological change. Arch Clin Neuropsychol. 2006 Jan; 21(1):83-9. PMID: 16169705.
      View in: PubMed
    205. Schweinsburg BC, Taylor MJ, Alhassoon OM, Gonzalez R, Brown GG, Ellis RJ, Letendre S, Videen JS, McCutchan JA, Patterson TL, Grant I. Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors. J Neurovirol. 2005 Aug; 11(4):356-64. PMID: 16206458.
      View in: PubMed
    206. Jernigan TL, Gamst AC, Archibald SL, Fennema-Notestine C, Mindt MR, Marcotte TD, Marcotte TL, Heaton RK, Ellis RJ, Grant I. Effects of methamphetamine dependence and HIV infection on cerebral morphology. Am J Psychiatry. 2005 Aug; 162(8):1461-72. PMID: 16055767.
      View in: PubMed
    207. Capparelli EV, Holland D, Okamoto C, Gragg B, Durelle J, Marquie-Beck J, van den Brande G, Ellis R, Letendre S. Lopinavir concentrations in cerebrospinal fluid exceed the 50% inhibitory concentration for HIV. AIDS. 2005 Jun 10; 19(9):949-52. PMID: 15905676.
      View in: PubMed
    208. Capparelli EV, Letendre SL, Ellis RJ, Patel P, Holland D, McCutchan JA. Population pharmacokinetics of abacavir in plasma and cerebrospinal fluid. Antimicrob Agents Chemother. 2005 Jun; 49(6):2504-6. PMID: 15917556; PMCID: PMC1140502.
      View in: PubMed, PubMed Central
    209. Letendre S, Marquie-Beck J, Singh KK, de Almeida S, Zimmerman J, Spector SA, Grant I, Ellis R. The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid. J Neuroimmunol. 2004 Dec; 157(1-2):193-6. PMID: 15579297.
      View in: PubMed
    210. Singh KK, Ellis RJ, Marquie-Beck J, Letendre S, Heaton RK, Grant I, Spector SA. CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults. J Neuroimmunol. 2004 Dec; 157(1-2):185-92. PMID: 15579296.
      View in: PubMed
    211. Yiannoutsos CT, Ernst T, Chang L, Lee PL, Richards T, Marra CM, Meyerhoff DJ, Jarvik JG, Kolson D, Schifitto G, Ellis RJ, Swindells S, Simpson DM, Miller EN, Gonzalez RG, Navia BA. Regional patterns of brain metabolites in AIDS dementia complex. Neuroimage. 2004 Nov; 23(3):928-35. PMID: 15528093.
      View in: PubMed
    212. Langford D, Grigorian A, Hurford R, Adame A, Ellis RJ, Hansen L, Masliah E. Altered P-glycoprotein expression in AIDS patients with HIV encephalitis. J Neuropathol Exp Neurol. 2004 Oct; 63(10):1038-47. PMID: 15535131.
      View in: PubMed
    213. Letendre SL, McCutchan JA, Childers ME, Woods SP, Lazzaretto D, Heaton RK, Grant I, Ellis RJ. Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders. Ann Neurol. 2004 Sep; 56(3):416-23. PMID: 15349869.
      View in: PubMed
    214. Archibald SL, Masliah E, Fennema-Notestine C, Marcotte TD, Ellis RJ, McCutchan JA, Heaton RK, Grant I, Mallory M, Miller A, Jernigan TL. Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss. Arch Neurol. 2004 Mar; 61(3):369-76. PMID: 15023814.
      View in: PubMed
    215. Cherner M, Ellis RJ, Lazzaretto D, Young C, Mindt MR, Atkinson JH, Grant I, Heaton RK. Effects of HIV-1 infection and aging on neurobehavioral functioning: preliminary findings. AIDS. 2004 Jan 01; 18 Suppl 1:S27-34. PMID: 15075495.
      View in: PubMed
    216. Langford D, Adame A, Grigorian A, Grant I, McCutchan JA, Ellis RJ, Marcotte TD, Masliah E. Patterns of selective neuronal damage in methamphetamine-user AIDS patients. J Acquir Immune Defic Syndr. 2003 Dec 15; 34(5):467-74. PMID: 14657756.
      View in: PubMed
    217. Ellis RJ, Childers ME, Cherner M, Lazzaretto D, Letendre S, Grant I. Increased human immunodeficiency virus loads in active methamphetamine users are explained by reduced effectiveness of antiretroviral therapy. J Infect Dis. 2003 Dec 15; 188(12):1820-6. PMID: 14673760.
      View in: PubMed
    218. Marcotte TD, Deutsch R, McCutchan JA, Moore DJ, Letendre S, Ellis RJ, Wallace MR, Heaton RK, Grant I. Prediction of incident neurocognitive impairment by plasma HIV RNA and CD4 levels early after HIV seroconversion. Arch Neurol. 2003 Oct; 60(10):1406-12. PMID: 14568811.
      View in: PubMed
    219. Ellis RJ, Childers ME, Zimmerman JD, Frost SD, Deutsch R, McCutchan JA. Human immunodeficiency virus-1 RNA levels in cerebrospinal fluid exhibit a set point in clinically stable patients not receiving antiretroviral therapy. J Infect Dis. 2003 Jun 01; 187(11):1818-21. PMID: 12751041.
      View in: PubMed
    220. Gonzalez R, Heaton RK, Moore DJ, Letendre S, Ellis RJ, Wolfson T, Marcotte T, Cherner M, Rippeth J, Grant I. Computerized reaction time battery versus a traditional neuropsychological battery: detecting HIV-related impairments. J Int Neuropsychol Soc. 2003 Jan; 9(1):64-71. PMID: 12570359.
      View in: PubMed
    221. Ellis RJ, Moore DJ, Childers ME, Letendre S, McCutchan JA, Wolfson T, Spector SA, Hsia K, Heaton RK, Grant I. Progression to neuropsychological impairment in human immunodeficiency virus infection predicted by elevated cerebrospinal fluid levels of human immunodeficiency virus RNA. Arch Neurol. 2002 Jun; 59(6):923-8. PMID: 12056927.
      View in: PubMed
    222. Espey MG, Basile AS, Heaton RK, Ellis RJ. Increased glutamate in CSF and plasma of patients with HIV dementia. Neurology. 2002 May 14; 58(9):1439; author reply 1439-40. PMID: 12011305.
      View in: PubMed
    223. Langford TD, Letendre SL, Marcotte TD, Ellis RJ, McCutchan JA, Grant I, Mallory ME, Hansen LA, Archibald S, Jernigan T, Masliah E. Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy. AIDS. 2002 May 03; 16(7):1019-29. PMID: 11953468; PMCID: PMC3548569.
      View in: PubMed, PubMed Central
    224. Ellis RJ, Gamst AC, Capparelli E, Spector SA, Hsia K, Wolfson T, Abramson I, Grant I, McCutchan JA. Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology. 2000 Feb 22; 54(4):927-36. PMID: 10690988.
      View in: PubMed
    225. Ellis RJ, Seubert P, Motter R, Galasko D, Deutsch R, Heaton RK, Heyes MP, McCutchan JA, Atkinson JH, Grant I. Cerebrospinal fluid tau protein is not elevated in HIV-associated neurologic disease in humans. HIV Neurobehavioral Research Center Group (HNRC). Neurosci Lett. 1998 Sep 18; 254(1):1-4. PMID: 9780077.
      View in: PubMed
    226. Ellis RJ, Jan K, Kawas C, Koller WC, Lyons KE, Jeste DV, Hansen LA, Thal LJ. Diagnostic validity of the dementia questionnaire for Alzheimer disease. Arch Neurol. 1998 Mar; 55(3):360-5. PMID: 9520010.
      View in: PubMed
    227. Ellis RJ, Deutsch R, Heaton RK, Marcotte TD, McCutchan JA, Nelson JA, Abramson I, Thal LJ, Atkinson JH, Wallace MR, Grant I. Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group. Arch Neurol. 1997 Apr; 54(4):416-24. PMID: 9109743.
      View in: PubMed
    Ronald's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (565) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (88) people
    _
    Similar People
    People who share similar concepts with this person.
    See all (60) people
    _
    Same Department
    Search Department
    ↑