Cynthia Hsu

Title(s)Assistant Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-2604-1340 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UC San DiegoMD/PhD2018
    Collapse Awards and Honors
    AASLD2023  - 2025Clinical, Translational, and Outcomes Research Award
    UC San Diego2023  - 2024Physician Scientist Training Program Pilot Project Award
    Southern California Research Center for ALPD and Cirrhosis2023  - 2023Pilot Project Award
    American Gastroenterological Association2023  - 2025Fellowship-to-faculty Transition Award (declined due to concurrent award)

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Role of gut microbial ethanol production in alcohol use disorder and alcohol-associated liver disease
    NIH K99AA031328Sep 20, 2023 - Aug 31, 2025
    Role: Principal Investigator
    The role of gut microbial ethanol production in alcohol use disorder and alcohol-associated liver disease
    American Association for the Study of Liver Diseases CTORA23-208366Jul 1, 2023 - Jun 30, 2025
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research. Nat Metab. 2024 Feb 21. Hsu CL, Loomba R. PMID: 38383845.
      View in: PubMed   Mentions:    Fields:    
    2. Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis. Hepatology. 2024 Feb 20. Yamazaki T, Kouno T, Hsu CL, Hartmann P, Mayo S, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Schnabl B, AlcHepNet Investigators. PMID: 38377466.
      View in: PubMed   Mentions:    Fields:    
    3. The gut-liver axis and gut microbiota in health and liver disease. Nat Rev Microbiol. 2023 Nov; 21(11):719-733. Hsu CL, Schnabl B. PMID: 37316582; PMCID: PMC10794111.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    4. MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex. Life Sci Alliance. 2023 Aug; 6(8). Branch MR, Hsu CL, Ohnishi K, Shen WC, Lee E, Meisenhelder J, Winborn B, Sopher BL, Taylor JP, Hunter T, La Spada AR. PMID: 37221017; PMCID: PMC10205607.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Alcohol, the gut microbiome, and liver disease. J Gastroenterol Hepatol. 2023 Aug; 38(8):1205-1210. Jew MH, Hsu CL. PMID: 37096652.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Differences in Bacterial Translocation and Liver Injury in Ethanol Versus Diet-Induced Liver Disease. Dig Dis Sci. 2023 07; 68(7):3059-3069. Hsu CL, Wang Y, Duan Y, Chu H, Hartmann P, Llorente C, Zhou R, Schnabl B. PMID: 36807831; PMCID: PMC10313731.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    7. Any alcohol use in NAFLD patients is associated with significant changes to the intestinal virome. Hepatology. 2023 Jun 01; 77(6):2073-2083. Hsu CL, Lang S, Demir M, Fouts DE, Stärkel P, Schnabl B. PMID: 36631002; PMCID: PMC10192041.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Intestinal virome in patients with alcohol use disorder and after abstinence. Hepatol Commun. 2022 08; 6(8):2058-2069. Hsu CL, Zhang X, Jiang L, Lang S, Hartmann P, Pride D, Fouts DE, Stärkel P, Schnabl B. PMID: 35368152; PMCID: PMC9315129.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. Intestinal virome and therapeutic potential of bacteriophages in liver disease. J Hepatol. 2021 12; 75(6):1465-1475. Hsu CL, Duan Y, Fouts DE, Schnabl B. PMID: 34437908; PMCID: PMC8929164.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    10. Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease. Gut. 2019 10; 68(10):1884-1892. Caussy C, Ajmera VH, Puri P, Hsu CL, Bassirian S, Mgdsyan M, Singh S, Faulkner C, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Sanyal AJ, Loomba R. PMID: 30567742; PMCID: PMC8328048.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    11. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Aliment Pharmacol Ther. 2019 01; 49(2):183-193. Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R. PMID: 30506692; PMCID: PMC6319963.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    12. Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants. Clin Gastroenterol Hepatol. 2019 03; 17(4):630-637.e8. Hsu C, Caussy C, Imajo K, Chen J, Singh S, Kaulback K, Le MD, Hooker J, Tu X, Bettencourt R, Yin M, Sirlin CB, Ehman RL, Nakajima A, Loomba R. PMID: 29908362; PMCID: PMC6294709.
      View in: PubMed   Mentions: 133     Fields:    Translation:Humans
    13. Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2018 09; 68(3):918-932. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, Loomba R, Genetics of NAFLD in Twins Consortium. PMID: 29572891; PMCID: PMC6151296.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    14. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018 03 05; 9(1):942. Hsu CL, Lee EX, Gordon KL, Paz EA, Shen WC, Ohnishi K, Meisenhelder J, Hunter T, La Spada AR. PMID: 29507340; PMCID: PMC5838220.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    15. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Sci Transl Med. 2017 Dec 06; 9(419). Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, Ross CA, Masliah E, Evans RM, La Spada AR. PMID: 29212711; PMCID: PMC5748332.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    16. Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy. Cell Metab. 2014 Oct 07; 20(4):626-38. Dubinsky AN, Dastidar SG, Hsu CL, Zahra R, Djakovic SN, Duarte S, Esau CC, Spencer B, Ashe TD, Fischer KM, MacKenna DA, Sopher BL, Masliah E, Gaasterland T, Chau BN, Pereira de Almeida L, Morrison BE, La Spada AR. PMID: 25295787; PMCID: PMC4245205.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    17. Cdc42 GTPase and Rac1 GTPase act downstream of p120 catenin and require GTP exchange during gastrulation of zebrafish mesoderm. Dev Dyn. 2012 Oct; 241(10):1545-61. Hsu CL, Muerdter CP, Knickerbocker AD, Walsh RM, Zepeda-Rivera MA, Depner KH, Sangesland M, Cisneros TB, Kim JY, Sanchez-Vazquez P, Cherezova L, Regan RD, Bahrami NM, Gray EA, Chan AY, Chen T, Rao MY, Hille MB. PMID: 22911626.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    18. Rare copy number variants are an important cause of epileptic encephalopathies. Ann Neurol. 2011 Dec; 70(6):974-85. Mefford HC, Yendle SC, Hsu C, Cook J, Geraghty E, McMahon JM, Eeg-Olofsson O, Sadleir LG, Gill D, Ben-Zeev B, Lerman-Sagie T, Mackay M, Freeman JL, Andermann E, Pelakanos JT, Andrews I, Wallace G, Eichler EE, Berkovic SF, Scheffer IE. PMID: 22190369; PMCID: PMC3245646.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
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