Fred Gage

Title(s)Adjunct Professor, Neurobiology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Neuronal senescence and inflammation in Alzheimer's disease
    NIH RF1AG072502Apr 1, 2021 - Mar 31, 2024
    Role: Principal Investigator
    Combinatorial Actions of Genetic Variants and Gender Bias of Alzherimer's Disease
    NIH R01AG057706Sep 30, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Dynamics of activity-induced transcription in single dentate granule cells
    NIH R01MH114030Aug 1, 2017 - May 31, 2022
    Role: Principal Investigator
    Assessing cellular aging in old and rejuvenated neurons from Alzheimer patients
    NIH R01AG056306Jul 15, 2017 - Apr 30, 2022
    Role: Principal Investigator
    iPSC-based platform development for major psychiatric disorder modeling and discovery
    NIH U19MH106434Aug 17, 2016 - May 31, 2021
    Role: Co-Principal Investigator
    3/3-Schizophrenia Genetics and Brain Somatic Mosaicism
    NIH U01MH106882Apr 20, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Exploring Human-Induced Pluripotent Stem Cells for Alzheimer's Disease Research
    NIH RF1AG042985Sep 1, 2012 - Aug 31, 2014
    Role: Co-Principal Investigator
    Development and Analysis of hiPSCs for Studies on Addiction
    NIH R21DA032986Sep 30, 2011 - Jul 31, 2014
    Role: Co-Principal Investigator
    Single-Cell Approaches to Reveal How Jumping Genes Individualize Neural Circuits
    NIH R01MH095741Sep 20, 2011 - Jun 30, 2016
    Role: Principal Investigator
    DISTINCTIVE SPATIOTEMPORAL MAP OF TARGET ACTIVATION BY YOUNG NEURONS OF THE ADULT
    NIH R03TW008607Jan 1, 2011 - Jun 30, 2015
    Role: Co-Principal Investigator
    Functional Analysis of Adult Hippocampal Neurogenesis
    NIH R01MH090258Apr 2, 2010 - Jan 31, 2015
    Role: Principal Investigator
    L1 Retrotransposon and Neural Diversity
    NIH R01MH088485Aug 12, 2009 - Oct 30, 2013
    Role: Principal Investigator
    The Role of MeCP2 in L1 Neuronal Retrotransposition
    NIH R56MH082070Sep 30, 2008 - Sep 29, 2009
    Role: Principal Investigator
    Translational Research of AAV-IGF-1 Gene Therapy for ALS
    NIH U01NS048925Sep 15, 2005 - Feb 28, 2009
    Role: Principal Investigator
    Role of Astrocyte-Derived Wnts in Adult Neurogenesis
    NIH R01NS050217May 18, 2005 - Apr 30, 2010
    Role: Principal Investigator
    smRNA-Mediated Regulation of Adult Neural Stem Cell Fate
    NIH R01NS052842May 18, 2005 - Apr 30, 2009
    Role: Principal Investigator
    Neurophysiology of Adult Substantia Nigra Stem Cells
    NIH R03TW006130Jan 1, 2003 - Dec 31, 2005
    Role: Principal Investigator
    Gene Targeting and Regulation for Neurological Disease
    NIH R01AG021876Aug 15, 2002 - Jul 31, 2007
    Role: Principal Investigator
    Function of Stem Cell-Derived Neurons in the Aging Brain
    NIH R01AG020938Apr 1, 2002 - Mar 31, 2008
    Role: Principal Investigator
    Conference on Stem Cells: Origins, Fate and Functions
    NIH R13NS042933Jan 1, 2002 - Dec 31, 2002
    Role: Principal Investigator
    THERAPEUTIC POTENTIALS OF CNS STEM CELLS
    NIH R13NS039557Jul 1, 1999 - Jun 30, 2000
    Role: Principal Investigator
    NEURONAL PRECURSOR CELLS FOR TRANSPLANT AFTER CNS TRAUMA
    NIH/NINDS N01NS062348Sep 30, 1996 - Sep 29, 2002
    Role: Principal Investigator
    NEURONAL PRECURSOR CELLS FOR TRANSPLANTATION AFTER CNS
    NIH/NINDS N01NS062349Sep 30, 1996 - Sep 29, 2002
    Role: Co-Principal Investigator
    Training in the Neuroplasticity of Aging
    NIH T32AG000216Sep 30, 1992 - Apr 30, 2018
    Role: Co-Principal Investigator
    Gene Therapy for Alzheimer's Disease
    NIH P01AG010435Sep 30, 1991 - Mar 31, 2016
    Role: Co-Principal Investigator
    Cell Genesis in the Intact and Injured Substantia Nigra
    NIH R01AG008514Jul 1, 1989 - Jun 30, 2006
    Role: Principal Investigator
    GRAFTING GENETICALLY MODIFIED CELLS TO THE BRAIN
    NIH R37AG008514Jul 1, 1989 - Jun 30, 2001
    Role: Principal Investigator
    CHARACTERIZATION &UTILIZATION OF ADULT PROGENITOR CELLS
    NIH R01AG006088Jul 1, 1985 - Feb 28, 2002
    Role: Principal Investigator
    EMBRYONIC NERVE CELL TRANSPLANTATION IN BRAINS OF AGED
    NIH R01AG003766Apr 1, 1983 - Jun 30, 1985
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Neural Organoids and the Quest to Understand and Treat Psychiatric Disease. Biol Psychiatry. 2023 04 01; 93(7):588-589. Arlotta P, Gage FH. PMID: 36889858.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. Mol Psychiatry. 2023 Mar 29. Niemsiri V, Rosenthal SB, Nievergelt CM, Maihofer AX, Marchetto MC, Santos R, Shekhtman T, Alliey-Rodriguez N, Anand A, Balaraman Y, Berrettini WH, Bertram H, Burdick KE, Calabrese JR, Calkin CV, Conroy C, Coryell WH, DeModena A, Eyler LT, Feeder S, Fisher C, Frazier N, Frye MA, Gao K, Garnham J, Gershon ES, Goes FS, Goto T, Harrington GJ, Jakobsen P, Kamali M, Kelly M, Leckband SG, Lohoff FW, McCarthy MJ, McInnis MG, Craig D, Millett CE, Mondimore F, Morken G, Nurnberger JI, Donovan CO, ?edegaard KJ, Ryan K, Schinagle M, Shilling PD, Slaney C, Stapp EK, Stautland A, Tarwater B, Zandi PP, Alda M, Fisch KM, Gage FH, Kelsoe JR. PMID: 36991131.
      View in: PubMed   Mentions:    Fields:    
    3. Adult neurogenesis in the hippocampus. Hippocampus. 2023 Apr; 33(4):269-270. Kempermann G, Song H, Gage FH. PMID: 36912499.
      View in: PubMed   Mentions:    Fields:    
    4. Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells. Hippocampus. 2023 04; 33(4):412-423. Parylak SL, Qiu F, Linker SB, Gallina IS, Lim CK, Preciado D, McDonald AH, Zhou X, Gage FH. PMID: 36811254.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy. Neurosci Lett. 2023 02 16; 797:137080. Perez-Garcia G, Bicak M, Haure-Mirande JV, Perez GM, Otero-Pagan A, Gama Sosa MA, De Gasperi R, Sano M, Barlow C, Gage FH, Readhead B, Ehrlich ME, Gandy S, Elder GA. PMID: 36657633; PMCID: PMC9974759.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Transplantation Strategies to Enhance Maturity and Cellular Complexity in Brain Organoids. Biol Psychiatry. 2023 04 01; 93(7):616-621. Wang M, Gage FH, Schafer ST. PMID: 36739209.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nat Commun. 2022 12 26; 13(1):7945. Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, Kuzum D. PMID: 36572698; PMCID: PMC9792589.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Novel correlative analysis identifies multiple genomic variations impacting ASD with macrocephaly. Hum Mol Genet. 2022 Dec 15. Fu C, Ngo J, Zhang S, Lu L, Miron A, Schafer S, Gage FH, Jin F, Schumacher FR, Wynshaw-Boris A. PMID: 36519762.
      View in: PubMed   Mentions:    Fields:    
    9. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. Cell Stem Cell. 2022 12 01; 29(12):1637-1652.e6. Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH. PMID: 36459967; PMCID: PMC10093780.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. NPJ Parkinsons Dis. 2022 Oct 18; 8(1):134. van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, Winner B, Winkler J, Gage FH, Bardy C. PMID: 36258029; PMCID: PMC9579158.
      View in: PubMed   Mentions: 1  
    11. Human-specific regulation of neural maturation identified by cross-primate transcriptomics. Curr Biol. 2022 Nov 21; 32(22):4797-4807.e5. Linker SB, Narvaiza I, Hsu JY, Wang M, Qiu F, Mendes APD, Oefner R, Kottilil K, Sharma A, Randolph-Moore L, Mejia E, Santos R, Marchetto MC, Gage FH. PMID: 36228612.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. A nomenclature consensus for nervous system organoids and assembloids. Nature. 2022 09; 609(7929):907-910. Pa?ca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Muotri AR, Park IH, Reiner O, Song H, Studer L, Temple S, Testa G, Treutlein B, Vaccarino FM. PMID: 36171373.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metab. 2022 09 06; 34(9):1248-1263.e6. Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, Mertens J. PMID: 35987203; PMCID: PMC9458870.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients. NPJ Parkinsons Dis. 2022 Aug 10; 8(1):103. Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, Qiu F, Schafer S, Mansour AA, Mangan KP, Stern T, Ofer P, Stern Y, Diniz Mendes AP, Djamus J, Moore LR, Nayak R, Laufer SH, Aicher A, Rhee A, Wong TL, Nguyen T, Linker SB, Winner B, Freitas BC, Jones E, Sagi I, Bardy C, Brice A, Winkler J, Marchetto MC, Gage FH. PMID: 35948563; PMCID: PMC9365794.
      View in: PubMed   Mentions: 1  
    15. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science. 2022 07 29; 377(6605):511-517. Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA, Brain Somatic Mosaicism Network§, Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. PMID: 35901164; PMCID: PMC9420557.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Methods for culturing adult CNS neurons reveal a CNS conditioning effect. Cell Rep Methods. 2022 Jul 18; 2(7):100255. van Niekerk EA, Kawaguchi R, Marques de Freria C, Groeniger K, Marchetto MC, Dupraz S, Bradke F, Geschwind DH, Gage FH, Tuszynski MH. PMID: 35880023; PMCID: PMC9308166.
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    17. Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders. Front Neurosci. 2022; 16:884707. Bermperidis T, Schafer S, Gage FH, Sejnowski T, Torres EB. PMID: 35720720; PMCID: PMC9201694.
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    18. Oleic acid regulates hippocampal neurogenesis as a TLX ligand. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2203038119. Shi Y, Evans RM, Gage FH. PMID: 35344400; PMCID: PMC9169763.
      View in: PubMed   Mentions:    Fields:    
    19. Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients. Transl Psychiatry. 2021 11 30; 11(1):608. Heard KJ, Shokhirev MN, Becronis C, Fredlender C, Zahid N, Le AT, Ji Y, Skime M, Nelson T, Hall-Flavin D, Weinshilboum R, Gage FH, Vadodaria KC. PMID: 34848679; PMCID: PMC8632962.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Adult neurogenesis in neurological diseases. Science. 2021 Nov 26; 374(6571):1049-1050. Gage FH. PMID: 34822282.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. The San Diego Nathan Shock Center: tackling the heterogeneity of aging. Geroscience. 2021 10; 43(5):2139-2148. Shadel GS, Adams PD, Berggren WT, Diedrich JK, Diffenderfer KE, Gage FH, Hah N, Hansen M, Hetzer MW, Molina AJA, Manor U, Marek K, O'Keefe DD, Pinto AFM, Sacco A, Sharpee TO, Shokriev MN, Zambetti S. PMID: 34370163; PMCID: PMC8599742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. The role of retrotransposable elements in ageing and age-associated diseases. Nature. 2021 08; 596(7870):43-53. Gorbunova V, Seluanov A, Mita P, McKerrow W, Fenyö D, Boeke JD, Linker SB, Gage FH, Kreiling JA, Petrashen AP, Woodham TA, Taylor JR, Helfand SL, Sedivy JM. PMID: 34349292; PMCID: PMC8600649.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    23. AAV ablates neurogenesis in the adult murine hippocampus. Elife. 2021 07 14; 10. Johnston S, Parylak SL, Kim S, Mac N, Lim C, Gallina I, Bloyd C, Newberry A, Saavedra CD, Novak O, Gonçalves JT, Gage FH, Shtrahman M. PMID: 34259630; PMCID: PMC8331179.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    24. The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 06 08; 118(23). Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF. PMID: 34083437; PMCID: PMC8201764.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho. Mol Psychiatry. 2021 11; 26(11):6365-6379. Dias GP, Murphy T, Stangl D, Ahmet S, Morisse B, Nix A, Aimone LJ, Aimone JB, Kuro-O M, Gage FH, Thuret S. PMID: 34031536; PMCID: PMC8760057.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    26. To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly. Proc Natl Acad Sci U S A. 2021 05 11; 118(19). Schafer ST, Gage FH. PMID: 33883269; PMCID: PMC8126768.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    27. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. 2021 09 02; 28(9):1533-1548.e6. Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. PMID: 33910058; PMCID: PMC8423435.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    28. Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. Science. 2021 04 02; 372(6537):91-94. Reid DA, Reed PJ, Schlachetzki JCM, Nitulescu II, Chou G, Tsui EC, Jones JR, Chandran S, Lu AT, McClain CA, Ooi JH, Wang TW, Lana AJ, Linker SB, Ricciardulli AS, Lau S, Schafer ST, Horvath S, Dixon JR, Hah N, Glass CK, Gage FH. PMID: 33795458; PMCID: PMC9179101.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    29. Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. Mol Psychiatry. 2021 07; 26(7):2753-2763. Nakatsuka N, Heard KJ, Faill?taz A, Momotenko D, V?r?s J, Gage FH, Vadodaria KC. PMID: 33767349; PMCID: PMC9997689.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    30. Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies. Mol Psychiatry. 2021 07; 26(7):3383-3394. Mishra HK, Ying NM, Luis A, Wei H, Nguyen M, Nakhla T, Vandenburgh S, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Frye MA, Gage FH, Gershon ES, McInnis MG, Nievergelt CM, Nurnberger JI, Shilling PD, Oedegaard KJ, Zandi PP, Pharmacogenomics of Bipolar Disorder Study, Kelsoe JR, Welsh DK, McCarthy MJ. PMID: 33674753; PMCID: PMC8418615.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    31. Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. Stem Cell Reports. 2021 04 13; 16(4):825-835. Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, Gage FH. PMID: 33667413; PMCID: PMC8072028.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    32. The When and Where: Molecular and Cellular Convergence in Autism. Biol Psychiatry. 2021 03 01; 89(5):419-420. Schafer ST, Gage FH. PMID: 33541523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. Proc Natl Acad Sci U S A. 2021 02 09; 118(6). Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, Magner E, Liu X, Sun J, Wang M, Baker K, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Pandey A, Pandya L, Cummings T, Banerjee D, Huang P, Yerramothu P, Tolstonog GV, Held U, Erwin JA, Paquola ACM, Herdy JR, Ogura Y, Terasaki H, Oshika T, Darwish S, Singh RK, Mozaffari S, Bhattarai D, Kim KB, Hardin JW, Bennett CL, Hinton DR, Hanson TE, Röver C, Parang K, Kerur N, Liu J, Werner BC, Sutton SS, Sadda SR, Schumann GG, Gelfand BD, Gage FH, Ambati J. PMID: 33526699; PMCID: PMC8017980.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    34. Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients. Mol Psychiatry. 2021 06; 26(6):2440-2456. Santos R, Linker SB, Stern S, Mendes APD, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Kim Y, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH. PMID: 33398088; PMCID: PMC9129103.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    35. Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis. EMBO J. 2021 02 01; 40(3):e105819. Bedrosian TA, Houtman J, Eguiguren JS, Ghassemzadeh S, Rund N, Novaresi NM, Hu L, Parylak SL, Denli AM, Randolph-Moore L, Namba T, Gage FH, Toda T. PMID: 33300615; PMCID: PMC7849303.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    36. Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31438-31447. Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J. PMID: 33229564; PMCID: PMC7733786.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    37. Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus. Genome Res. 2020 11; 30(11):1643-1654. Linker SB, Randolph-Moore L, Kottilil K, Qiu F, Jaeger BN, Barron J, Gage FH. PMID: 33122305; PMCID: PMC7605253.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    38. Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis. Mol Psychiatry. 2021 07; 26(7):3558-3571. Figueiredo T, Mendes APD, Moreira DP, Goulart E, Oliveira D, Kobayashi GS, Stern S, Kok F, Marchetto MC, Santos R, Gage FH, Zatz M. PMID: 32839513.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination. J Biol Chem. 2020 08 21; 295(34):12233-12246. Kerman BE, Genoud S, Kurt Vatandaslar B, Denli AM, Georges Ghosh S, Xu X, Yeo GW, Aimone JB, Gage FH. PMID: 32647008; PMCID: PMC7443494.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    40. Cellular complexity in brain organoids: Current progress and unsolved issues. Semin Cell Dev Biol. 2021 03; 111:32-39. Mansour AA, Schafer ST, Gage FH. PMID: 32499191.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    41. Modeling Brain Disorders Using Induced Pluripotent Stem Cells. Cold Spring Harb Perspect Biol. 2020 06 01; 12(6). Vadodaria KC, Jones JR, Linker S, Gage FH. PMID: 31767646; PMCID: PMC7263088.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    42. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):10055-10066. Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MCN, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR, Gleeson JG. PMID: 32312822; PMCID: PMC7211998.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    43. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Cell Rep Med. 2020 04 21; 1(1):100002. Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming GL, Gage FH, Diamond DJ, Wussow F, Shi Y. PMID: 33205055; PMCID: PMC7659592.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    44. Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods. 2020 03; 17(3):353. Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Belmonte JCI. PMID: 32034376.
      View in: PubMed   Mentions:    Fields:    
    45. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4392-4399. Shen W, Wang QW, Liu YN, Marchetto MC, Linker S, Lu SY, Chen Y, Liu C, Guo C, Xing Z, Shi W, Kelsoe JR, Alda M, Wang H, Zhong Y, Sui SF, Zhao M, Yang Y, Mi S, Cao L, Gage FH, Yao J. PMID: 32041882; PMCID: PMC7049155.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    46. A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients. Biol Psychiatry. 2020 07 15; 88(2):150-158. Stern S, Sarkar A, Galor D, Stern T, Mei A, Stern Y, Mendes APD, Randolph-Moore L, Rouleau G, Bang AG, Santos R, Alda M, Marchetto MC, Gage FH. PMID: 32278494.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability. Cell Stem Cell. 2020 02 06; 26(2):221-233.e6. Wang M, Wei PC, Lim CK, Gallina IS, Marshall S, Marchetto MC, Alt FW, Gage FH. PMID: 32004479; PMCID: PMC7175642.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    48. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038; PMCID: PMC9628766.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    49. Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. Science. 2019 11 29; 366(6469):1134-1139. Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. PMID: 31727856; PMCID: PMC7028213.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansCells
    50. Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder. Biol Psychiatry. 2020 07 15; 88(2):139-149. Stern S, Sarkar A, Stern T, Mei A, Mendes APD, Stern Y, Goldberg G, Galor D, Nguyen T, Randolph-Moore L, Kim Y, Rouleau G, Bang A, Alda M, Santos R, Marchetto MC, Gage FH. PMID: 31732108; PMCID: PMC7108962.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    51. Dynamical Electrical Complexity Is Reduced during Neuronal Differentiation in Autism Spectrum Disorder. Stem Cell Reports. 2019 09 10; 13(3):474-484. Amatya DN, Linker SB, Mendes APD, Santos R, Erikson G, Shokhirev MN, Zhou Y, Sharpee T, Gage FH, Marchetto MC, Kim Y. PMID: 31474529; PMCID: PMC6739708.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    52. An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack KNa Currents. J Neurosci. 2019 09 11; 39(37):7438-7449. Quraishi IH, Stern S, Mangan KP, Zhang Y, Ali SR, Mercier MR, Marchetto MC, McLachlan MJ, Jones EM, Gage FH, Kaczmarek LK. PMID: 31350261; PMCID: PMC6759030.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    53. Prediction of Response to Drug Therapy in Psychiatric Disorders. Focus (Am Psychiatr Publ). 2019 Jul; 17(3):294-307. Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. PMID: 32015721; PMCID: PMC6996058.
      View in: PubMed   Mentions: 1  
    54. Corrigendum: Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Front Mol Neurosci. 2019; 12:150. van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C. PMID: 31244603; PMCID: PMC6580186.
      View in: PubMed   Mentions: 2  
    55. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 2019 Jun 06; 24(6):1006. Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B. PMID: 31173705.
      View in: PubMed   Mentions: 11     Fields:    
    56. Adult neurogenesis in mammals. Science. 2019 May 31; 364(6443):827-828. Gage FH. PMID: 31147506.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    57. Modeling neuropsychiatric disorders using human induced pluripotent stem cells. Protein Cell. 2020 01; 11(1):45-59. Wang M, Zhang L, Gage FH. PMID: 31134525; PMCID: PMC6949328.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    58. Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons. Elife. 2019 05 17; 8. Herdy J, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola A, Lee H, Mertens J, Gage FH. PMID: 31099332; PMCID: PMC6524968.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    59. Nerve cells from the brain invade prostate tumours. Nature. 2019 05; 569(7758):637-638. Schafer ST, Gage FH. PMID: 31138915.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    60. Entrainment of Circadian Rhythms to Temperature Reveals Amplitude Deficits in Fibroblasts from Patients with Bipolar Disorder and Possible Links to Calcium Channels. Mol Neuropsychiatry. 2019 Apr; 5(2):115-124. Nudell V, Wei H, Nievergelt C, Maihofer AX, Shilling P, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Covault JM, Frye MA, Gage F, Gershon E, McInnis MG, Nurnberger JI, Oedegaard KJ, Shekhtman T, Zandi PP, Kelsoe JR, McCarthy MJ. PMID: 31192224; PMCID: PMC6528084.
      View in: PubMed   Mentions: 4  
    61. Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons. Mol Psychiatry. 2019 06; 24(6):808-818. Vadodaria KC, Ji Y, Skime M, Paquola AC, Nelson T, Hall-Flavin D, Heard KJ, Fredlender C, Deng Y, Elkins J, Dani K, Le AT, Marchetto MC, Weinshilboum R, Gage FH. PMID: 30903001; PMCID: PMC7409972.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    62. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019 03; 567(7749):535-539. Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. PMID: 30867594; PMCID: PMC6557285.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    63. Microglia, complement and schizophrenia. Nat Neurosci. 2019 03; 22(3):333-334. Wang M, Zhang L, Gage FH. PMID: 30796420.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    64. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 2019 02 07; 8. Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH. PMID: 30730291; PMCID: PMC6366899.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    65. Mitochondria, Metabolism, and Redox Mechanisms in Psychiatric Disorders. Antioxid Redox Signal. 2019 08 01; 31(4):275-317. Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. PMID: 30585734; PMCID: PMC6602118.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    66. Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons. Mol Psychiatry. 2019 06; 24(6):795-807. Vadodaria KC, Ji Y, Skime M, Paquola A, Nelson T, Hall-Flavin D, Fredlender C, Heard KJ, Deng Y, Le AT, Dave S, Fung L, Li X, Marchetto MC, Weinshilboum R, Gage FH. PMID: 30700803.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    67. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 2019 Jan 16; 101(2):349. Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. PMID: 30653936; PMCID: PMC6377243.
      View in: PubMed   Mentions: 7     Fields:    
    68. BrainImageR: spatiotemporal gene set analysis referencing the human brain. Bioinformatics. 2019 01 15; 35(2):343-345. Linker SB, Hsu JY, Pfaff A, Amatya D, Ko SM, Voter S, Wong Q, Gage FH. PMID: 30010719; PMCID: PMC6657270.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    69. Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat Neurosci. 2019 02; 22(2):243-255. Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH. PMID: 30617258; PMCID: PMC6402576.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    70. Centrifugal Inputs to the Main Olfactory Bulb Revealed Through Whole Brain Circuit-Mapping. Front Neuroanat. 2018; 12:115. Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. PMID: 30666191; PMCID: PMC6330333.
      View in: PubMed   Mentions: 22  
    71. Limits to human neurogenesis-really? Mol Psychiatry. 2020 10; 25(10):2207-2209. Lucassen PJ, Toni N, Kempermann G, Frisen J, Gage FH, Swaab DF. PMID: 30617274; PMCID: PMC7515796.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    72. Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology. 2019 02; 44(3):620-628. McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, Calabrese JR, Calkin CV, Claasen A, Conroy C, Coryell WH, Craig DW, D'Arcangelo N, Demodena A, Djurovic S, Feeder S, Fisher C, Frazier N, Frye MA, Gage FH, Gao K, Garnham J, Gershon ES, Glazer K, Goes F, Goto T, Harrington G, Jakobsen P, Kamali M, Karberg E, Kelly M, Leckband SG, Lohoff F, McInnis MG, Mondimore F, Morken G, Nurnberger JI, Obral S, Oedegaard KJ, Ortiz A, Ritchey M, Ryan K, Schinagle M, Schoeyen H, Schwebel C, Shaw M, Shekhtman T, Slaney C, Stapp E, Szelinger S, Tarwater B, Zandi PP, Kelsoe JR. PMID: 30487653; PMCID: PMC6333516.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    73. Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector. Front Mol Neurosci. 2018; 11:415. Suh H, Zhou QG, Fernandez-Carasa I, Clemenson GD, Pons-Espinal M, Ro EJ, Marti M, Raya A, Gage FH, Consiglio A. PMID: 30498432; PMCID: PMC6249367.
      View in: PubMed   Mentions: 3  
    74. Adult Hippocampal Neurogenesis: A Coming-of-Age Story. J Neurosci. 2018 12 05; 38(49):10401-10410. Kuhn HG, Toda T, Gage FH. PMID: 30381404; PMCID: PMC6284110.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    75. Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases. Annu Rev Genet. 2018 11 23; 52:271-293. Mertens J, Reid D, Lau S, Kim Y, Gage FH. PMID: 30208291; PMCID: PMC6415910.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    76. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science. 2018 09 07; 361(6406). Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, Kim DY, van Praag H, Spiegelman BM, Gage FH, Tanzi RE. PMID: 30190379; PMCID: PMC6149542.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansAnimals
    77. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 2018 09 05; 99(5):925-940.e7. Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. PMID: 30189209; PMCID: PMC6240334.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    78. Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Front Mol Neurosci. 2018; 11:261. van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C. PMID: 30147644; PMCID: PMC6096303.
      View in: PubMed   Mentions: 19  
    79. A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. Nat Commun. 2018 08 06; 9(1):3084. Jaeger BN, Linker SB, Parylak SL, Barron JJ, Gallina IS, Saavedra CD, Fitzpatrick C, Lim CK, Schafer ST, Lacar B, Jessberger S, Gage FH. PMID: 30082781; PMCID: PMC6079101.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    80. Erratum: An in vivo model of functional and vascularized human brain organoids. Nat Biotechnol. 2018 08 06; 36(8):772. Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH. PMID: 30080830.
      View in: PubMed   Mentions: 6     Fields:    
    81. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 2018 Jul 05; 23(1):123-131.e6. Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B. PMID: 29979986.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    82. Author Correction: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2018 Jul; 21(7):1016. Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 29703932.
      View in: PubMed   Mentions: 2     Fields:    
    83. Author Correction: CRISPR interference-based specific and efficient gene inactivation in the brain. Nat Neurosci. 2018 Jun; 21(6):894. Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. PMID: 29545585.
      View in: PubMed   Mentions: 6     Fields:    
    84. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Rep. 2018 05 29; 23(9):2550-2558. Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH. PMID: 29847787; PMCID: PMC6478017.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    85. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Sci Transl Med. 2018 05 09; 10(440). Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud AN, Marsala S, Kafka J, Miyanohara A, Kato T, Tadokoro T, Hefferan MP, Kamizato K, Yoshizumi T, Juhas S, Juhasova J, Ho CS, Kheradmand T, Chen P, Bohaciakova D, Hruska-Plochan M, Todd AJ, Driscoll SP, Glenn TD, Pfaff SL, Klima J, Ciacci J, Curtis E, Gage FH, Bui J, Yamada K, Muotri AR, Marsala M. PMID: 29743351.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    86. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell Stem Cell. 2018 05 03; 22(5):684-697.e9. Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH. PMID: 29727680; PMCID: PMC6345574.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    87. Prediction of response to drug therapy in psychiatric disorders. Open Biol. 2018 05; 8(5). Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. PMID: 29794033; PMCID: PMC5990649.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    88. The role of adult hippocampal neurogenesis in brain health and disease. Mol Psychiatry. 2019 01; 24(1):67-87. Toda T, Parylak SL, Linker SB, Gage FH. PMID: 29679070; PMCID: PMC6195869.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansCells
    89. Human Adult Neurogenesis: Evidence and Remaining Questions. Cell Stem Cell. 2018 Jul 05; 23(1):25-30. Kempermann G, Gage FH, Aigner L, Song H, Curtis MA, Thuret S, Kuhn HG, Jessberger S, Frankland PW, Cameron HA, Gould E, Hen R, Abrous DN, Toni N, Schinder AF, Zhao X, Lucassen PJ, Frisén J. PMID: 29681514; PMCID: PMC6035081.
      View in: PubMed   Mentions: 278     Fields:    Translation:HumansCells
    90. An in vivo model of functional and vascularized human brain organoids. Nat Biotechnol. 2018 06; 36(5):432-441. Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, Johnston S, Parylak SL, Jin X, Gage FH. PMID: 29658944; PMCID: PMC6331203.
      View in: PubMed   Mentions: 376     Fields:    Translation:HumansAnimalsCells
    91. Early life experience drives structural variation of neural genomes in mice. Science. 2018 03 23; 359(6382):1395-1399. Bedrosian TA, Quayle C, Novaresi N, Gage FH. PMID: 29567711.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    92. CRISPR interference-based specific and efficient gene inactivation in the brain. Nat Neurosci. 2018 03; 21(3):447-454. Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. PMID: 29403034.
      View in: PubMed   Mentions: 72     Fields:    Translation:Animals
    93. Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. Genome Med. 2018 01 04; 10(1):1. Vadodaria KC, Amatya DN, Marchetto MC, Gage FH. PMID: 29301565; PMCID: PMC5755287.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    94. MicroRNAs in Post-traumatic Stress Disorder. Curr Top Behav Neurosci. 2018; 38:23-46. Snijders C, de Nijs L, Baker DG, Hauger RL, van den Hove D, Kenis G, Nievergelt CM, Boks MP, Vermetten E, Gage FH, Rutten BPF. PMID: 29063484.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    95. Review: adult neurogenesis contributes to hippocampal plasticity. Cell Tissue Res. 2018 Sep; 373(3):693-709. Toda T, Gage FH. PMID: 29185071.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    96. Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation. Mol Aspects Med. 2018 06; 61:50-62. Jaeger BN, Parylak SL, Gage FH. PMID: 29117513.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    97. Corrigendum: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2017 Sep 28; 20(10):1427. Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 28949329.
      View in: PubMed   Mentions:    Fields:    
    98. An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis. Mol Psychiatry. 2018 07; 23(7):1674-1684. Shahsavani M, Pronk RJ, Falk R, Lam M, Moslem M, Linker SB, Salma J, Day K, Schuster J, Anderlid BM, Dahl N, Gage FH, Falk A. PMID: 28924182.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    99. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell. 2017 Nov 02; 21(5):618-634.e7. Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer MW, Gage FH. PMID: 28919367.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    100. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Rep. 2017 09 05; 20(10):2525. Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ. PMID: 28877483; PMCID: PMC5599129.
      View in: PubMed   Mentions: 5     Fields:    
    101. Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons. Cell Tissue Res. 2018 01; 371(1):161-170. Vadodaria KC, Stern S, Marchetto MC, Gage FH. PMID: 28812143.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    102. Examining non-LTR retrotransposons in the context of the evolving primate brain. BMC Biol. 2017 08 11; 15(1):68. Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH. PMID: 28800766; PMCID: PMC5554003.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    103. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5635-E5644. Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W. PMID: 28630288; PMCID: PMC5514719.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    104. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 06 06; 8(6):1757-1769. Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH. PMID: 28591655; PMCID: PMC5470172.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    105. An environment-dependent transcriptional network specifies human microglia identity. Science. 2017 06 23; 356(6344). Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. PMID: 28546318; PMCID: PMC5858585.
      View in: PubMed   Mentions: 402     Fields:    Translation:HumansAnimalsCells
    106. Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. Nat Commun. 2017 05 02; 8:15157. Ishii S, Torii M, Son AI, Rajendraprasad M, Morozov YM, Kawasawa YI, Salzberg AC, Fujimoto M, Brennand K, Nakai A, Mezger V, Gage FH, Rakic P, Hashimoto-Torii K. PMID: 28462912; PMCID: PMC5418582.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    107. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science. 2017 04 28; 356(6336). McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, Mills RE, Paquola ACM, Rodin RE, Rosenbluh C, Sestan N, Sherman MA, Shin JH, Song S, Straub RE, Thorpe J, Weinberger DR, Urban AE, Zhou B, Gage FH, Lehner T, Senthil G, Walsh CA, Chess A, Courchesne E, Gleeson JG, Kidd JM, Park PJ, Pevsner J, Vaccarino FM, Brain Somatic Mosaicism Network. PMID: 28450582; PMCID: PMC5558435.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    108. Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2017 04 15; 31(8):845. Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 28512238; PMCID: PMC5435895.
      View in: PubMed   Mentions:    Fields:    
    109. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat Commun. 2017 03 17; 8:15047. Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. PMID: 28303884; PMCID: PMC5357833.
      View in: PubMed   Mentions: 1     Fields:    
    110. Conserved expression of transposon-derived non-coding transcripts in primate stem cells. BMC Genomics. 2017 02 28; 18(1):214. Ramsay L, Marchetto MC, Caron M, Chen SH, Busche S, Kwan T, Pastinen T, Gage FH, Bourque G. PMID: 28245871; PMCID: PMC5331655.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    111. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Mol Psychiatry. 2018 06; 23(6):1453-1465. Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. PMID: 28242870; PMCID: PMC5573640.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    112. Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges. Front Cell Neurosci. 2017; 11:30. Kim Y, Santos R, Gage FH, Marchetto MC. PMID: 28261061; PMCID: PMC5306135.
      View in: PubMed   Mentions: 25  
    113. Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology. J Neurosci. 2017 02 15; 37(7):1675-1684. Adamowicz DH, Roy S, Salmon DP, Galasko DR, Hansen LA, Masliah E, Gage FH. PMID: 28039370; PMCID: PMC5320602.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    114. Insights into the role of somatic mosaicism in the brain. Curr Opin Syst Biol. 2017 Feb; 1:90-94. Paquola ACM, Erwin JA, Gage FH. PMID: 29226270; PMCID: PMC5718369.
      View in: PubMed   Mentions: 19  
    115. A role for miR-19 in the migration of adult-born neurons and schizophrenia. Neurogenesis (Austin). 2016; 3(1):e1251873. Han J, Gage FH. PMID: 28405585; PMCID: PMC5384614.
      View in: PubMed   Mentions: 6  
    116. Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior. Cell. 2016 Nov 03; 167(4):897-914. Gonçalves JT, Schafer ST, Gage FH. PMID: 27814520.
      View in: PubMed   Mentions: 397     Fields:    Translation:HumansAnimalsCells
    117. Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology. Mol Psychiatry. 2016 11; 21(11):1573-1588. Bardy C, van den Hurk M, Kakaradov B, Erwin JA, Jaeger BN, Hernandez RV, Eames T, Paucar AA, Gorris M, Marchand C, Jappelli R, Barron J, Bryant AK, Kellogg M, Lasken RS, Rutten BP, Steinbusch HW, Yeo GW, Gage FH. PMID: 27698428; PMCID: PMC5071135.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    118. Generating human serotonergic neurons in vitro: Methodological advances. Bioessays. 2016 11; 38(11):1123-1129. Vadodaria KC, Marchetto MC, Mertens J, Gage FH. PMID: 27716980.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    119. L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci. 2016 12; 19(12):1583-1591. Erwin JA, Paquola AC, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FI, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. PMID: 27618310; PMCID: PMC5127747.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    120. Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):E5501-10. Du H, Deng W, Aimone JB, Ge M, Parylak S, Walch K, Zhang W, Cook J, Song H, Wang L, Gage FH, Mu Y. PMID: 27573822; PMCID: PMC5027420.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    121. A human neurodevelopmental model for Williams syndrome. Nature. 2016 08 18; 536(7616):338-43. Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR. PMID: 27509850; PMCID: PMC4995142.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    122. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. 2016 08 11; 536(7615):205-9. Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, Denman L, Harshman L, Baker C, Raja A, Penewit K, Janke N, Tang WJ, Ventura M, Banci L, Antonacci F, Akey JM, Amemiya CT, Gage FH, Reymond A, Eichler EE. PMID: 27487209; PMCID: PMC4988886.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    123. Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency. Epigenomics. 2016 08; 8(8):1131-49. van den Hurk M, Kenis G, Bardy C, van den Hove DL, Gage FH, Steinbusch HW, Rutten BP. PMID: 27419933; PMCID: PMC5514980.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    124. Diverse Representations of Olfactory Information in Centrifugal Feedback Projections. J Neurosci. 2016 07 13; 36(28):7535-45. Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. PMID: 27413162; PMCID: PMC4945671.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    125. Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain. Neuron. 2016 07 06; 91(1):79-89. Han J, Kim HJ, Schafer ST, Paquola A, Clemenson GD, Toda T, Oh J, Pankonin AR, Lee BS, Johnston ST, Sarkar A, Denli AM, Gage FH. PMID: 27387650.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    126. Aging and Rejuvenation: Insights from Rusty Gage, Leonard Guarente, and Amy Wagers. Trends Mol Med. 2016 08; 22(8):633-634. Gage FH, Guarente LP, Wagers AJ. PMID: 27396512.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    127. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry. 2017 06; 22(6):820-835. Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR. PMID: 27378147; PMCID: PMC5215991.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansCells
    128. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat Commun. 2016 06 14; 7:12020. Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. PMID: 27295945; PMCID: PMC4911670.
      View in: PubMed   Mentions: 4     Fields:    
    129. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. Elife. 2016 06 10; 5. Zheng X, Boyer L, Jin M, Mertens J, Kim Y, Ma L, Ma L, Hamm M, Gage FH, Hunter T. PMID: 27282387; PMCID: PMC4963198.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansCells
    130. Environment-driven somatic mosaicism in brain disorders. Genome Med. 2016 05 23; 8(1):58. Bedrosian TA, Linker S, Gage FH. PMID: 27215330; PMCID: PMC4877941.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    131. What is memory? The present state of the engram. BMC Biol. 2016 05 19; 14:40. Poo MM, Pignatelli M, Ryan TJ, Tonegawa S, Bonhoeffer T, Martin KC, Rudenko A, Tsai LH, Tsien RW, Fishell G, Mullins C, Gonçalves JT, Shtrahman M, Johnston ST, Gage FH, Dan Y, Long J, Buzsáki G, Stevens C. PMID: 27197636; PMCID: PMC4874022.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    132. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience. Nat Rev Neurosci. 2016 07; 17(7):424-37. Mertens J, Marchetto MC, Bardy C, Gage FH. PMID: 27194476; PMCID: PMC6276815.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    133. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2016 05 15; 30(10):1155-71. Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 27198230; PMCID: PMC4888837.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    134. The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample. BMC Psychiatry. 2016 May 05; 16:129. Oedegaard KJ, Alda M, Anand A, Andreassen OA, Balaraman Y, Berrettini WH, Bhattacharjee A, Brennand KJ, Burdick KE, Calabrese JR, Calkin CV, Claasen A, Coryell WH, Craig D, DeModena A, Frye M, Gage FH, Gao K, Garnham J, Gershon E, Jakobsen P, Leckband SG, McCarthy MJ, McInnis MG, Maihofer AX, Mertens J, Morken G, Nievergelt CM, Nurnberger J, Pham S, Schoeyen H, Shekhtman T, Shilling PD, Szelinger S, Tarwater B, Yao J, Zandi PP, Kelsoe JR. PMID: 27150464; PMCID: PMC4857276.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    135. In vivo imaging of dendritic pruning in dentate granule cells. Nat Neurosci. 2016 06; 19(6):788-91. Gonçalves JT, Bloyd CW, Shtrahman M, Johnston ST, Schafer ST, Parylak SL, Tran T, Chang T, Gage FH. PMID: 27135217; PMCID: PMC4941946.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    136. GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model. Ann Neurol. 2016 May; 79(5):826-840. Mishra HK, Prots I, Havlicek S, Kohl Z, Perez-Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, Schuierer G, Behrens J, Lampert A, Engel FB, Gage FH, Winkler J, Winner B. PMID: 26971897; PMCID: PMC5084783.
      View in: PubMed   Mentions: 24     Fields:    
    137. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Rep. 2016 05 03; 15(5):1024-1036. Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ. PMID: 27117414; PMCID: PMC4856588.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    138. Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat Commun. 2016 04 19; 7:11022. Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJE, Parylak SL, Paquola ACM, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. PMID: 27090946; PMCID: PMC4838832.
      View in: PubMed   Mentions: 164     Fields:    Translation:AnimalsCells
    139. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity. J Neurosci. 2016 Apr 13; 36(15):4259-75. Harrison BJ, Venkat G, Lamb JL, Hutson TH, Drury C, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill CE, Rouchka EC, Moon LD, Petruska JC. PMID: 27076424; PMCID: PMC4829650.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    140. α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathol. 2016 07; 132(1):59-75. Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. PMID: 27059609; PMCID: PMC4912450.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    141. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 2016 Apr 07; 18(4):467-80. Otani T, Marchetto MC, Gage FH, Simons BD, Livesey FJ. PMID: 27049876; PMCID: PMC4826446.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    142. Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration. Elife. 2016 03 23; 5. Zheng X, Boyer L, Jin M, Kim Y, Fan W, Bardy C, Berggren T, Evans RM, Gage FH, Hunter T. PMID: 27008180; PMCID: PMC4846388.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    143. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nat Protoc. 2016 Mar; 11(3):499-524. Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. PMID: 26890679; PMCID: PMC4941947.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansCells
    144. A Mechanism for Somatic Brain Mosaicism. Cell. 2016 Feb 11; 164(4):593-5. Weissman IL, Gage FH. PMID: 26871622.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    145. Training the next generation of biomedical investigators in glycosciences. J Clin Invest. 2016 Feb; 126(2):405-8. Agre P, Bertozzi C, Bissell M, Campbell KP, Cummings RD, Desai UR, Estes M, Flotte T, Fogleman G, Gage F, Ginsburg D, Gordon JI, Hart G, Hascall V, Kiessling L, Kornfeld S, Lowe J, Magnani J, Mahal LK, Medzhitov R, Roberts RJ, Sackstein R, Sarkar R, Schnaar R, Schwartz N, Varki A, Walt D, Weissman I. PMID: 26829621; PMCID: PMC4731185.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    146. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):751-6. Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. PMID: 26733678; PMCID: PMC4725523.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    147. The different moods of human serotonergic neurons. Mol Psychiatry. 2016 Jan; 21(1):3. Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. PMID: 26678308.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    148. Synaptic activity: An emerging player in schizophrenia. Brain Res. 2017 02 01; 1656:68-75. Sarkar A, Marchetto MC, Gage FH. PMID: 26723567.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    149. Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke. Brain. 2016 Jan; 139(Pt 1):259-75. Duricki DA, Hutson TH, Kathe C, Soleman S, Gonzalez-Carter D, Petruska JC, Shine HD, Chen Q, Wood TC, Bernanos M, Cash D, Williams SC, Gage FH, Moon LD. PMID: 26614754; PMCID: PMC4785394.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    150. Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2016 Feb 11; 530(7589):242. Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Oedegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM, Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. PMID: 26605530.
      View in: PubMed   Mentions: 3     Fields:    
    151. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. 2015 Dec 08; 5(6):933-945. Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. PMID: 26610635; PMCID: PMC4881284.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    152. Paradox of pattern separation and adult neurogenesis: A dual role for new neurons balancing memory resolution and robustness. Neurobiol Learn Mem. 2016 Mar; 129:60-8. Johnston ST, Shtrahman M, Parylak S, Gonçalves JT, Gage FH. PMID: 26549627; PMCID: PMC4792723.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    153. REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. J Neurosci. 2015 Nov 04; 35(44):14872-84. Kim HJ, Denli AM, Wright R, Baul TD, Clemenson GD, Morcos AS, Zhao C, Schafer ST, Gage FH, Kagalwala MN. PMID: 26538656; PMCID: PMC4635134.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    154. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. 2015 Nov 05; 527(7576):95-9. Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Alba M, Nievergelt CM, Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. PMID: 26524527; PMCID: PMC4742055.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansCells
    155. Generation of functional human serotonergic neurons from fibroblasts. Mol Psychiatry. 2016 Jan; 21(1):49-61. Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. PMID: 26503761.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    156. Primate-specific ORF0 contributes to retrotransposon-mediated diversity. Cell. 2015 Oct 22; 163(3):583-93. Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. PMID: 26496605.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    157. Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain. Elife. 2015 Oct 16; 4:e07871. Mu Y, Zhao C, Toni N, Yao J, Gage FH. PMID: 26473971; PMCID: PMC4608052.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    158. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. Cell Stem Cell. 2015 Dec 03; 17(6):705-718. Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. PMID: 26456686; PMCID: PMC5929130.
      View in: PubMed   Mentions: 290     Fields:    Translation:HumansCells
    159. Purification and Injection of Retroviral Vectors. Cold Spring Harb Protoc. 2015 Oct 01; 2015(10):925-31. Tashiro A, Zhao C, Suh H, Gage FH. PMID: 26430255.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    160. Preparation and Use of Retroviral Vectors for Labeling, Imaging, and Genetically Manipulating Cells. Cold Spring Harb Protoc. 2015 Oct 01; 2015(10):883-8. Tashiro A, Zhao C, Suh H, Gage FH. PMID: 26430260.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    161. Imaging Newborn Granule Cells in Fixed Sections. Cold Spring Harb Protoc. 2015 Oct 01; 2015(10):932-3. Tashiro A, Zhao C, Suh H, Gage FH. PMID: 26430256.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    162. Analysis of Spine Motility of Newborn Granule Cells in Acute Brain Slices. Cold Spring Harb Protoc. 2015 Oct 01; 2015(10):934-6. Tashiro A, Zhao C, Suh H, Gage FH. PMID: 26430257.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    163. Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest. Cell. 2015 Sep 24; 163(1):68-83. Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J. PMID: 26365491; PMCID: PMC4848043.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansAnimalsCells
    164. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nat Neurosci. 2015 Sep; 18(9):1226-9. Jovicic A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. PMID: 26308983; PMCID: PMC4552077.
      View in: PubMed   Mentions: 317     Fields:    Translation:HumansAnimalsCells
    165. Neurogenesis in the Adult Hippocampus. Cold Spring Harb Perspect Biol. 2015 Sep 01; 7(9):a018812. Kempermann G, Song H, Gage FH. PMID: 26330519; PMCID: PMC4563705.
      View in: PubMed   Mentions: 337     Fields:    Translation:HumansCells
    166. Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs. Cell Rep. 2015 Sep 01; 12(9):1385-90. Firth AL, Menon T, Parker GS, Qualls SJ, Lewis BM, Ke E, Dargitz CT, Wright R, Khanna A, Gage FH, Verma IM. PMID: 26299960; PMCID: PMC4559351.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    167. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. J Comp Neurol. 2015 Jul 01; 523(10):1588. Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. PMID: 26109421.
      View in: PubMed   Mentions: 5     Fields:    
    168. MIR137: big impacts from small changes. Nat Neurosci. 2015 Jul; 18(7):931-3. Han J, Sarkar A, Gage FH. PMID: 26108719.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    169. In vitro myelin formation using embryonic stem cells. Development. 2015 Jun 15; 142(12):2213-25. Kerman BE, Kim HJ, Padmanabhan K, Mei A, Georges S, Joens MS, Fitzpatrick JA, Jappelli R, Chandross KJ, August P, Gage FH. PMID: 26015546; PMCID: PMC4483765.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    170. Alzheimer's disease: distinct stages in neurogenic decline? Biol Psychiatry. 2015 Apr 15; 77(8):680-2. Adamowicz DH, Mertens J, Gage FH. PMID: 25835286.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    171. Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):E2725-34. Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, Gage FH. PMID: 25870293; PMCID: PMC4443325.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansCells
    172. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. Cell Metab. 2015 Apr 07; 21(4):628-36. Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM. PMID: 25863252; PMCID: PMC4393848.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    173. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2015 Apr 14; 112(15):E1936-45. Amador-Arjona A, Cimadamore F, Huang CT, Wright R, Lewis S, Gage FH, Terskikh AV. PMID: 25825708; PMCID: PMC4403144.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    174. The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. J Neurosci. 2015 Mar 25; 35(12):4983-98. Schafer ST, Han J, Pena M, von Bohlen Und Halbach O, Peters J, Gage FH. PMID: 25810528; PMCID: PMC4389597.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    175. The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory. Front Syst Neurosci. 2015; 9:34. Deng W, Gage FH. PMID: 25798094; PMCID: PMC4351587.
      View in: PubMed   Mentions: 10  
    176. Improving and accelerating drug development for nervous system disorders. Neuron. 2014 Nov 05; 84(3):546-53. Pankevich DE, Altevogt BM, Dunlop J, Gage FH, Hyman SE. PMID: 25442933; PMCID: PMC4254615.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    177. Enrichment rescues contextual discrimination deficit associated with immediate shock. Hippocampus. 2015 Mar; 25(3):385-92. Clemenson GD, Lee SW, Deng W, Barrera VR, Iwamoto KS, Fanselow MS, Gage FH. PMID: 25330953; PMCID: PMC4398310.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    178. Regulation and function of adult neurogenesis: from genes to cognition. Physiol Rev. 2014 Oct; 94(4):991-1026. Aimone JB, Li Y, Lee SW, Clemenson GD, Deng W, Gage FH. PMID: 25287858; PMCID: PMC4280160.
      View in: PubMed   Mentions: 252     Fields:    Translation:HumansAnimalsCells
    179. Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons. Stem Cell Reports. 2014 Oct 14; 3(4):531-8. Hook V, Brennand KJ, Kim Y, Toneff T, Funkelstein L, Lee KC, Ziegler M, Gage FH. PMID: 25358781; PMCID: PMC4223699.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    180. Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse. Mol Psychiatry. 2014 Nov; 19(11):1235-42. Kim SH, Steele JW, Lee SW, Clemenson GD, Carter TA, Treuner K, Gadient R, Wedel P, Glabe C, Barlow C, Ehrlich ME, Gage FH, Gandy S. PMID: 25113378; PMCID: PMC4217144.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    181. Adult neurogenesis: bridging the gap between mice and humans. Trends Cell Biol. 2014 Oct; 24(10):558-63. Jessberger S, Gage FH. PMID: 25124338.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    182. QnAs with Fred Gage. Proc Natl Acad Sci U S A. 2014 Sep 09; 111(36):12958-9. Gage F, Nair P. PMID: 25049423; PMCID: PMC4246929.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    183. Mobile DNA elements in the generation of diversity and complexity in the brain. Nat Rev Neurosci. 2014 Aug; 15(8):497-506. Erwin JA, Marchetto MC, Gage FH. PMID: 25005482; PMCID: PMC4443810.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    184. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 2014 Jul 02; 83(1):69-86. Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. PMID: 24991955; PMCID: PMC4277209.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    185. How to make a hippocampal dentate gyrus granule neuron. Development. 2014 Jun; 141(12):2366-75. Yu DX, Marchetto MC, Gage FH. PMID: 24917496.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    186. Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories. Hippocampus. 2014 Aug; 24(8):905-11. Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. PMID: 24825389; PMCID: PMC4312906.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    187. Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. Hum Mol Genet. 2014 Sep 15; 23(R1):R27-34. Winner B, Marchetto MC, Winkler J, Gage FH. PMID: 24821704.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    188. Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Struct Funct. 2015 Jul; 220(4):2027-42. Krzisch M, Temprana SG, Mongiat LA, Armida J, Schmutz V, Virtanen MA, Kocher-Braissant J, Kraftsik R, Vutskits L, Conzelmann KK, Bergami M, Gage FH, Schinder AF, Toni N. PMID: 24748560; PMCID: PMC4481333.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    189. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. J Comp Neurol. 2014 Aug 15; 522(12):2756-66. Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. PMID: 24610721; PMCID: PMC4065223.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    190. Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. Neuron. 2014 May 07; 82(3):560-72. Hashimoto-Torii K, Torii M, Fujimoto M, Nakai A, El Fatimy R, Mezger V, Ju MJ, Ishii S, Chao SH, Brennand KJ, Gage FH, Rakic P. PMID: 24726381; PMCID: PMC4051437.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    191. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Mol Psychiatry. 2015 Mar; 20(3):361-8. Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR, Gage FH. PMID: 24686136; PMCID: PMC4182344.
      View in: PubMed   Mentions: 218     Fields:    Translation:HumansAnimalsCells
    192. Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):E1723-30. Firth AL, Dargitz CT, Qualls SJ, Menon T, Wright R, Singer O, Gage FH, Khanna A, Verma IM. PMID: 24706852; PMCID: PMC4035971.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    193. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain. 2014 May; 137(Pt 5):1496-513. Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, Winner B, Masliah E. PMID: 24662516; PMCID: PMC3999721.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    194. Role of BRCA1 in brain development. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):E1240-8. Pao GM, Zhu Q, Perez-Garcia CG, Chou SJ, Suh H, Gage FH, O'Leary DD, Verma IM. PMID: 24639535; PMCID: PMC3977248.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    195. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21. Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. PMID: 24584051; PMCID: PMC4113004.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    196. Enhancing induced pluripotent stem cell models of schizophrenia. JAMA Psychiatry. 2014 Mar; 71(3):334-5. Wright R, Réthelyi JM, Gage FH. PMID: 24382673.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    197. SnapShot: adult hippocampal neurogenesis. Cell. 2014 Feb 27; 156(5):1114-1114.e1. Vadodaria KC, Gage FH. PMID: 24581504.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    198. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. 2014 Mar 11; 2(3):295-310. Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH. PMID: 24672753; PMCID: PMC3964286.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    199. Increasing the resolution of the adult neurogenesis picture. F1000Prime Rep. 2014; 6:8. Lacar B, Parylak SL, Vadodaria KC, Sarkar A, Gage FH. PMID: 24592320; PMCID: PMC3914506.
      View in: PubMed   Mentions: 9  
    200. Mother's milk programs offspring's cognition. Nat Neurosci. 2014 Jan; 17(1):8-9. Parylak SL, Deng W, Gage FH. PMID: 24369371.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    201. Your brain under the microscope: the promise of stem cells. Cerebrum. 2014 Jan; 2014:1. Marchetto MC, Gage FH. PMID: 25009691; PMCID: PMC4087191.
      View in: PubMed   Mentions: 5  
    202. Temporally selective contextual encoding in the dentate gyrus of the hippocampus. Nat Commun. 2014; 5:3181. Rangel LM, Alexander AS, Aimone JB, Wiles J, Gage FH, Chiba AA, Quinn LK. PMID: 24518986; PMCID: PMC3929785.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    203. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. Hum Mol Genet. 2014 May 15; 23(10):2527-41. Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B. PMID: 24381312; PMCID: PMC3990156.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    204. The role of transposable elements in health and diseases of the central nervous system. J Neurosci. 2013 Nov 06; 33(45):17577-86. Reilly MT, Faulkner GJ, Dubnau J, Ponomarev I, Gage FH. PMID: 24198348; PMCID: PMC3818539.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    205. Mosaic copy number variation in human neurons. Science. 2013 Nov 01; 342(6158):632-7. McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. PMID: 24179226; PMCID: PMC3975283.
      View in: PubMed   Mentions: 268     Fields:    Translation:HumansCells
    206. Neural stem cells: generating and regenerating the brain. Neuron. 2013 Oct 30; 80(3):588-601. Gage FH, Temple S. PMID: 24183012.
      View in: PubMed   Mentions: 219     Fields:    Translation:HumansAnimalsCells
    207. BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories. Cell Rep. 2013 Nov 14; 5(3):759-68. Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. PMID: 24209752; PMCID: PMC3898274.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    208. Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov; 140(22):4633-44. Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Šestan N, Gage FH, Lein ES. PMID: 24154525; PMCID: PMC3817946.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    209. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 2013 Nov 28; 503(7477):525-529. Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. PMID: 24153179; PMCID: PMC4064720.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    210. A regenerative approach to the treatment of multiple sclerosis. Nature. 2013 Oct 17; 502(7471):327-332. Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. PMID: 24107995; PMCID: PMC4431622.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    211. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Biol Psychiatry. 2014 Jun 15; 75(12):929-35. Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR. PMID: 24041506.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    212. P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury. PLoS One. 2013; 8(7):e69286. Sung TC, Chen Z, Thuret S, Vilar M, Gage FH, Riek R, Lee KF. PMID: 23935974; PMCID: PMC3720591.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    213. Therapeutic translation of iPSCs for treating neurological disease. Cell Stem Cell. 2013 Jun 06; 12(6):678-88. Yu DX, Marchetto MC, Gage FH. PMID: 23746977.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    214. Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Sci Transl Med. 2013 Jun 05; 5(188):188lr2. Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. PMID: 23740898.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    215. FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell. 2013 Jun; 12(3):518-22. Vilchez D, Boyer L, Lutz M, Merkwirth C, Morantte I, Tse C, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. PMID: 23551888; PMCID: PMC4864013.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    216. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Res. 2013 Sep; 11(2):743-57. Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. PMID: 23759711; PMCID: PMC3979966.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    217. A hypothesis for temporal coding of young and mature granule cells. Front Neurosci. 2013; 7:75. Rangel LM, Quinn LK, Chiba AA, Gage FH, Aimone JB. PMID: 23717259; PMCID: PMC3653099.
      View in: PubMed   Mentions: 17  
    218. Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2013 May 28; 110(22):9106-11. Li Y, Stam FJ, Aimone JB, Goulding M, Callaway EM, Gage FH. PMID: 23671081; PMCID: PMC3670356.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    219. Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiol Dis. 2013 Oct; 58:38-48. Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM, Bartus RT. PMID: 23631873.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    220. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nat Med. 2013 Apr; 19(4):473-80. Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, Zhang D, Gage FH, Ranscht B, Zhang YW, Lipton SA, Hong W, Xu H. PMID: 23524343; PMCID: PMC3911880.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    221. Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice. Elife. 2013 Mar 20; 2:e00312. Deng W, Mayford M, Gage FH. PMID: 23538967; PMCID: PMC3602954.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    222. Dynamic association of NUP98 with the human genome. PLoS Genet. 2013; 9(2):e1003308. Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer MW. PMID: 23468646; PMCID: PMC3585015.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    223. Paired related homeobox protein 1 is a regulator of stemness in adult neural stem/progenitor cells. J Neurosci. 2013 Feb 27; 33(9):4066-75. Shimozaki K, Clemenson GD, Gage FH. PMID: 23447615; PMCID: PMC6619329.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    224. Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods. 2013 Jan; 10(1):77-83. Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Izpisua Belmonte JC. PMID: 23202434; PMCID: PMC3531579.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    225. Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. J Neurosci. 2012 Nov 21; 32(47):16906-16. Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH. PMID: 23175842; PMCID: PMC4962062.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    226. Induced pluripotent stem cells: the new patient? Nat Rev Mol Cell Biol. 2012 Nov; 13(11):713-26. Bellin M, Marchetto MC, Gage FH, Mummery CL. PMID: 23034453.
      View in: PubMed   Mentions: 211     Fields:    Translation:HumansAnimalsCells
    227. An exploratory study of combination buspirone and melatonin SR in major depressive disorder (MDD): a possible role for neurogenesis in drug discovery. J Psychiatr Res. 2012 Dec; 46(12):1553-63. Fava M, Targum SD, Nierenberg AA, Bleicher LS, Carter TA, Wedel PC, Hen R, Gage FH, Barlow C. PMID: 22998742.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    228. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 2012 Sep 13; 489(7415):304-8. Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A. PMID: 22972301; PMCID: PMC5215918.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansCells
    229. Dopaminergic differentiation of human pluripotent cells. Curr Protoc Stem Cell Biol. 2012 Aug; Chapter 1:Unit1H.6. Boyer LF, Campbell B, Larkin S, Mu Y, Gage FH. PMID: 22872424.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    230. Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med. 2012 Aug 01; 4(145):145ra104. Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. PMID: 22855461.
      View in: PubMed   Mentions: 242     Fields:    Translation:HumansCells
    231. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12556-61. Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC. PMID: 22814375; PMCID: PMC3412010.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    232. Modeling brain disease in a dish: really? Cell Stem Cell. 2012 Jun 14; 10(6):642-645. Marchetto MC, Gage FH. PMID: 22704498.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    233. Electroconvulsive seizure promotes spine maturation in newborn dentate granule cells in adult rat. Dev Neurobiol. 2012 Jun; 72(6):937-42. Zhao C, Warner-Schmidt J, Duman RS, Gage FH. PMID: 21976455; PMCID: PMC3623264.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    234. Neural stem cells: mechanisms and modeling. Protein Cell. 2012 Apr; 3(4):251-61. Yao J, Mu Y, Gage FH. PMID: 22549585; PMCID: PMC4875476.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    235. Modeling psychiatric disorders at the cellular and network levels. Mol Psychiatry. 2012 Dec; 17(12):1239-53. Brennand KJ, Simone A, Tran N, Gage FH. PMID: 22472874; PMCID: PMC3465628.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    236. Local generation of glia is a major astrocyte source in postnatal cortex. Nature. 2012 Mar 28; 484(7394):376-80. Ge WP, Miyawaki A, Gage FH, Jan YN, Jan LY. PMID: 22456708; PMCID: PMC3777276.
      View in: PubMed   Mentions: 218     Fields:    Translation:AnimalsCells
    237. Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. J Neurosci. 2012 Mar 07; 32(10):3376-87. Bracko O, Singer T, Aigner S, Knobloch M, Winner B, Ray J, Clemenson GD, Suh H, Couillard-Despres S, Aigner L, Gage FH, Jessberger S. PMID: 22399759; PMCID: PMC3338187.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    238. What makes each brain unique. Sci Am. 2012 Mar; 306(3):26-31. Gage FH, Muotri AR. PMID: 22375319.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    239. Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network. Proc Natl Acad Sci U S A. 2012 Mar 13; 109(11):4290-5. Li Y, Aimone JB, Xu X, Callaway EM, Gage FH. PMID: 22371596; PMCID: PMC3306704.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    240. Enhanced functional recovery in MRL/MpJ mice after spinal cord dorsal hemisection. PLoS One. 2012; 7(2):e30904. Thuret S, Thallmair M, Horky LL, Gage FH. PMID: 22348029; PMCID: PMC3278405.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    241. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 2012 Jan 25; 482(7384):216-20. Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS. PMID: 22278060; PMCID: PMC3338985.
      View in: PubMed   Mentions: 579     Fields:    Translation:HumansCells
    242. ISSCR: beginning the next chapter. Cell Stem Cell. 2012 Jan 06; 10(1):29-31. Gage FH. PMID: 22226353.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    243. The enemy within: intronic miR-26b represses its host gene, ctdsp2, to regulate neurogenesis. Genes Dev. 2012 Jan 01; 26(1):6-10. Han J, Denli AM, Gage FH. PMID: 22215805; PMCID: PMC3258967.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    244. Monosynaptic inputs to new neurons in the dentate gyrus. Nat Commun. 2012; 3:1107. Vivar C, Potter MC, Choi J, Lee JY, Stringer TP, Callaway EM, Gage FH, Suh H, van Praag H. PMID: 23033083; PMCID: PMC4603575.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    245. Transplantation in the future. Prog Brain Res. 2012; 201:7-13. Gage FH. PMID: 23186707.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    246. Transplantation in the future. Prog Brain Res. 2012; 200:7-13. Gage FH. PMID: 23195412.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    247. Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats. Eur J Neurosci. 2012 Jan; 35(2):221-32. Boyce VS, Park J, Gage FH, Mendell LM. PMID: 22211901; PMCID: PMC3509221.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    248. Adult hippocampal neurogenesis and its role in Alzheimer's disease. Mol Neurodegener. 2011 Dec 22; 6:85. Mu Y, Gage FH. PMID: 22192775; PMCID: PMC3261815.
      View in: PubMed   Mentions: 366     Fields:    Translation:HumansAnimalsCells
    249. SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. J Biol Chem. 2012 Feb 17; 287(8):5969-78. Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH. PMID: 22194602; PMCID: PMC3285364.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    250. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20382-7. Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. PMID: 22159035; PMCID: PMC3251057.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    251. Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia. Stem Cells. 2011 Dec; 29(12):1915-22. Brennand KJ, Gage FH. PMID: 22009633; PMCID: PMC3381343.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    252. New neurons in an aged brain. Behav Brain Res. 2012 Feb 14; 227(2):497-507. Lee SW, Clemenson GD, Gage FH. PMID: 22024433; PMCID: PMC3264739.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    253. Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb. EMBO Mol Med. 2011 Dec; 3(12):742-54. Kuwabara T, Kagalwala MN, Onuma Y, Ito Y, Warashina M, Terashima K, Sanosaka T, Nakashima K, Gage FH, Asashima M. PMID: 21984534; PMCID: PMC3377118.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    254. Modeling psychiatric disorders through reprogramming. Dis Model Mech. 2012 Jan; 5(1):26-32. Brennand KJ, Gage FH. PMID: 21954066; PMCID: PMC3255540.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    255. BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature. 2011 Sep 07; 477(7363):179-84. Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH, Verma IM. PMID: 21901007; PMCID: PMC3240576.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansAnimalsCells
    256. Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises. Hum Mol Genet. 2011 Oct 15; 20(R2):R109-15. Marchetto MC, Brennand KJ, Boyer LF, Gage FH. PMID: 21828073; PMCID: PMC4447776.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    257. Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons. Stem Cells. 2011 Aug; 29(8):1231-40. Shen B, Xiang Z, Miller B, Louie G, Wang W, Noel JP, Gage FH, Wang L. PMID: 21681861; PMCID: PMC3209808.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    258. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Mol Ther. 2011 Oct; 19(10):1905-12. Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK. PMID: 21772256; PMCID: PMC3188742.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    259. Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines. Stem Cells. 2011 Jul; 29(7):1158-64. Woods NB, Parker AS, Moraghebi R, Lutz MK, Firth AL, Brennand KJ, Berggren WT, Raya A, Izpisúa Belmonte JC, Gage FH, Verma IM. PMID: 21544903; PMCID: PMC3254148.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    260. Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron. 2011 May 26; 70(4):589-96. Aimone JB, Deng W, Gage FH. PMID: 21609818; PMCID: PMC3240575.
      View in: PubMed   Mentions: 292     Fields:    Translation:HumansAnimals
    261. Modelling schizophrenia using human induced pluripotent stem cells. Nature. 2011 May 12; 473(7346):221-5. Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH. PMID: 21490598; PMCID: PMC3392969.
      View in: PubMed   Mentions: 639     Fields:    Translation:HumansCells
    262. Dopaminergic modulation of cortical inputs during maturation of adult-born dentate granule cells. J Neurosci. 2011 Mar 16; 31(11):4113-23. Mu Y, Zhao C, Gage FH. PMID: 21411652; PMCID: PMC3073019.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    263. Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One. 2011 Mar 02; 6(3):e17540. Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, Carson CT. PMID: 21407814; PMCID: PMC3047583.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansAnimalsCells
    264. Neurodegenerative disease and adult neurogenesis. Eur J Neurosci. 2011 Mar; 33(6):1139-51. Winner B, Kohl Z, Gage FH. PMID: 21395858.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansAnimalsCells
    265. Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis. Eur J Neurosci. 2011 Mar; 33(6):1160-9. Aimone JB, Gage FH. PMID: 21395860.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    266. In vivo demonstration that alpha-synuclein oligomers are toxic. Proc Natl Acad Sci U S A. 2011 Mar 08; 108(10):4194-9. Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R. PMID: 21325059; PMCID: PMC3053976.
      View in: PubMed   Mentions: 596     Fields:    Translation:AnimalsCells
    267. Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):3005-10. Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. PMID: 21278334; PMCID: PMC3041068.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    268. Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis. 2011 Mar; 41(3):706-16. Winner B, Melrose HL, Zhao C, Hinkle KM, Yue M, Kent C, Braithwaite AT, Ogholikhan S, Aigner R, Winkler J, Farrer MJ, Gage FH. PMID: 21168496; PMCID: PMC3059106.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    269. High-efficient generation of induced pluripotent stem cells from human astrocytes. PLoS One. 2010 Dec 09; 5(12):e15526. Ruiz S, Brennand K, Panopoulos AD, Herrerías A, Gage FH, Izpisua-Belmonte JC. PMID: 21170306; PMCID: PMC3000364.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    270. L1 retrotransposition in neurons is modulated by MeCP2. Nature. 2010 Nov 18; 468(7322):443-6. Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH. PMID: 21085180; PMCID: PMC3059197.
      View in: PubMed   Mentions: 315     Fields:    Translation:HumansAnimalsCells
    271. PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors. Exp Neurol. 2011 Jan; 227(1):210-7. Meng X, Arocena M, Penninger J, Gage FH, Zhao M, Song B. PMID: 21092738; PMCID: PMC3821524.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    272. A distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis. J Comp Neurol. 2010 Nov 15; 518(22):4479-90. Mathews EA, Morgenstern NA, Piatti VC, Zhao C, Jessberger S, Schinder AF, Gage FH. PMID: 20886617; PMCID: PMC2997649.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    273. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 2010 Nov 12; 143(4):527-39. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. PMID: 21074045; PMCID: PMC3003590.
      View in: PubMed   Mentions: 660     Fields:    Translation:HumansCells
    274. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci. 2010 Nov; 13(11):1338-44. Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. PMID: 20975758; PMCID: PMC3324277.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    275. Put them out to pasture? What are old granule cells good for, anyway...? Hippocampus. 2010 Oct; 20(10):1124-5. Aimone JB, Deng W, Gage FH. PMID: 20848611.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    276. Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats. Eur J Neurosci. 2010 Sep; 32(6):997-1005. Petruska JC, Kitay B, Boyce VS, Kaspar BK, Pearse DD, Gage FH, Mendell LM. PMID: 20849530; PMCID: PMC2943849.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    277. Puma is required for p53-induced depletion of adult stem cells. Nat Cell Biol. 2010 Oct; 12(10):993-8. Liu D, Ou L, Clemenson GD, Chao C, Lutske ME, Zambetti GP, Gage FH, Xu Y. PMID: 20818388; PMCID: PMC3025300.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    278. Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14863-8. Valdez G, Tapia JC, Kang H, Clemenson GD, Gage FH, Lichtman JW, Sanes JR. PMID: 20679195; PMCID: PMC2930485.
      View in: PubMed   Mentions: 256     Fields:    Translation:AnimalsCells
    279. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell. 2010 Jul 02; 7(1):78-89. Mira H, Andreu Z, Suh H, Lie DC, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, Marqués-Torrejón MA, Nakashima K, Colak D, Götz M, Fariñas I, Gage FH. PMID: 20621052.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansAnimalsCells
    280. Signaling in adult neurogenesis. Curr Opin Neurobiol. 2010 Aug; 20(4):416-23. Mu Y, Lee SW, Gage FH. PMID: 20471243; PMCID: PMC2942965.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    281. Adult neurogenesis: integrating theories and separating functions. Trends Cogn Sci. 2010 Jul; 14(7):325-37. Aimone JB, Deng W, Gage FH. PMID: 20471301; PMCID: PMC2904863.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    282. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends Neurosci. 2010 Aug; 33(8):345-54. Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH. PMID: 20471112; PMCID: PMC2916067.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    283. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum Mol Genet. 2010 Apr 15; 19(R1):R71-6. Marchetto MC, Winner B, Gage FH. PMID: 20418487; PMCID: PMC2875052.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    284. Spatial learning sculpts the dendritic arbor of adult-born hippocampal neurons. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7963-8. Tronel S, Fabre A, Charrier V, Oliet SH, Gage FH, Abrous DN. PMID: 20375283; PMCID: PMC2867872.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    285. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci. 2010 May; 11(5):339-50. Deng W, Aimone JB, Gage FH. PMID: 20354534; PMCID: PMC2886712.
      View in: PubMed   Mentions: 899     Fields:    Translation:HumansAnimalsCells
    286. Mechanisms underlying inflammation in neurodegeneration. Cell. 2010 Mar 19; 140(6):918-34. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. PMID: 20303880; PMCID: PMC2873093.
      View in: PubMed   Mentions: 1392     Fields:    Translation:HumansAnimals
    287. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. Keio J Med. 2010; 59(3):79-83. Gage FH. PMID: 20881448.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    288. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol. 2010 Jan; 12(1):31-40; sup pp 1-9. Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y. PMID: 20010817; PMCID: PMC2880892.
      View in: PubMed   Mentions: 148     Fields:    Translation:AnimalsCells
    289. Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Front Neurosci. 2009; 3:55. Overall RW, Kempermann G, Peirce J, Lu L, Goldowitz D, Gage FH, Goodwin S, Smit AB, Airey DC, Rosen GD, Schalkwyk LC, Sutter TR, Nowakowski RS, Whatley S, Williams RW. PMID: 20582282; PMCID: PMC2858614.
      View in: PubMed   Mentions: 52  
    290. [Epigenetic mechanisms regulating neural cell fate determination]. No To Hattatsu. 2009 Nov; 41(6):411-4. Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K. PMID: 19928537.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    291. Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain. J Neurosci. 2009 Oct 28; 29(43):13532-42. Deng W, Saxe MD, Gallina IS, Gage FH. PMID: 19864566; PMCID: PMC2787190.
      View in: PubMed   Mentions: 239     Fields:    Translation:AnimalsCells
    292. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus. 2009 Oct; 19(10):1002-7. Muotri AR, Zhao C, Marchetto MC, Gage FH. PMID: 19771587; PMCID: PMC2758700.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    293. Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends Neurosci. 2009 Nov; 32(11):575-82. Jessberger S, Gage FH, Eisch AJ, Lagace DC. PMID: 19782409; PMCID: PMC2767479.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    294. Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One. 2009 Sep 18; 4(9):e7076. Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. PMID: 19763270; PMCID: PMC2741600.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansAnimalsCells
    295. Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell. 2009 Sep 04; 5(3):310-9. Tamaki SJ, Jacobs Y, Dohse M, Capela A, Cooper JD, Reitsma M, He D, Tushinski R, Belichenko PV, Salehi A, Mobley W, Gage FH, Huhn S, Tsukamoto AS, Weissman IL, Uchida N. PMID: 19733542.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    296. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat Neurosci. 2009 Sep; 12(9):1097-105. Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH. PMID: 19701198; PMCID: PMC2764260.
      View in: PubMed   Mentions: 297     Fields:    Translation:AnimalsCells
    297. L1 retrotransposition in human neural progenitor cells. Nature. 2009 Aug 27; 460(7259):1127-31. Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH. PMID: 19657334; PMCID: PMC2909034.
      View in: PubMed   Mentions: 417     Fields:    Translation:HumansCells
    298. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science. 2009 Jul 10; 325(5937):210-3. Clelland CD, Choi M, Romberg C, Clemenson GD, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH, Bussey TJ. PMID: 19590004; PMCID: PMC2997634.
      View in: PubMed   Mentions: 724     Fields:    Translation:AnimalsCells
    299. Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. Hippocampus. 2009 Jul; 19(7):658-69. Thuret S, Toni N, Aigner S, Yeo GW, Gage FH. PMID: 19140178.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    300. Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. J Neurotrauma. 2009 Jul; 26(7):941-53. Fortun J, Puzis R, Pearse DD, Gage FH, Bunge MB. PMID: 19275471.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    301. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J Neurosci. 2009 Jun 24; 29(25):7966-77. Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC. PMID: 19553437; PMCID: PMC2776747.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
    302. Alpha9 integrin promotes neurite outgrowth on tenascin-C and enhances sensory axon regeneration. J Neurosci. 2009 Apr 29; 29(17):5546-57. Andrews MR, Czvitkovich S, Dassie E, Vogelaar CF, Faissner A, Blits B, Gage FH, ffrench-Constant C, Fawcett JW. PMID: 19403822; PMCID: PMC6665849.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    303. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 2009 Apr 03; 137(1):47-59. Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. PMID: 19345186; PMCID: PMC2754279.
      View in: PubMed   Mentions: 426     Fields:    Translation:AnimalsCells
    304. miR-9 and TLX: chasing tails in neural stem cells. Nat Struct Mol Biol. 2009 Apr; 16(4):346-7. Denli AM, Cao X, Gage FH. PMID: 19343066.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    305. Notch keeps ependymal cells in line. Nat Neurosci. 2009 Mar; 12(3):243-5. Zhao C, Suh H, Gage FH. PMID: 19238183.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    306. Computational influence of adult neurogenesis on memory encoding. Neuron. 2009 Jan 29; 61(2):187-202. Aimone JB, Wiles J, Gage FH. PMID: 19186162; PMCID: PMC2670434.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    307. Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn Mem. 2009 Feb; 16(2):147-54. Jessberger S, Clark RE, Broadbent NJ, Clemenson GD, Consiglio A, Lie DC, Squire LR, Gage FH. PMID: 19181621; PMCID: PMC2661246.
      View in: PubMed   Mentions: 310     Fields:    Translation:AnimalsCells
    308. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. J Neurosci. 2009 Jan 28; 29(4):1115-25. Rose JB, Crews L, Rockenstein E, Adame A, Mante M, Hersh LB, Gage FH, Spencer B, Potkar R, Marr RA, Masliah E. PMID: 19176820; PMCID: PMC2768399.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    309. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat Struct Mol Biol. 2009 Feb; 16(2):130-7. Yeo GW, Coufal NG, Liang TY, Peng GE, Fu XD, Gage FH. PMID: 19136955; PMCID: PMC2735254.
      View in: PubMed   Mentions: 329     Fields:    Translation:HumansCells
    310. Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use. Trends Pharmacol Sci. 2009 Feb; 30(2):61-5. Jessberger S, Gage FH. PMID: 19135265; PMCID: PMC2752320.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    311. Development of a novel mouse glioma model using lentiviral vectors. Nat Med. 2009 Jan; 15(1):110-6. Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH, Verma IM. PMID: 19122659; PMCID: PMC2671237.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    312. Development of neural circuits in the adult hippocampus. Curr Top Dev Biol. 2009; 87:149-74. Li Y, Mu Y, Gage FH. PMID: 19427519.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    313. Signaling in adult neurogenesis. Annu Rev Cell Dev Biol. 2009; 25:253-75. Suh H, Deng W, Gage FH. PMID: 19575663.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansAnimalsCells
    314. Genomic anatomy of the hippocampus. Neuron. 2008 Dec 26; 60(6):1010-21. Thompson CL, Pathak SD, Jeromin A, Ng LL, MacPherson CR, Mortrud MT, Cusick A, Riley ZL, Sunkin SM, Bernard A, Puchalski RB, Gage FH, Jones AR, Bajic VB, Hawrylycz MJ, Lein ES. PMID: 19109908.
      View in: PubMed   Mentions: 165     Fields:    Translation:Animals
    315. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 2008 Dec 04; 3(6):649-57. Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH. PMID: 19041781.
      View in: PubMed   Mentions: 238     Fields:    Translation:HumansAnimalsCells
    316. Stem-cell-associated structural and functional plasticity in the aging hippocampus. Psychol Aging. 2008 Dec; 23(4):684-91. Jessberger S, Gage FH. PMID: 19140640; PMCID: PMC2771615.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    317. YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev. 2008 Dec 01; 22(23):3320-34. Cao X, Pfaff SL, Gage FH. PMID: 19015275; PMCID: PMC2600760.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansAnimalsCells
    318. Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice. BMC Neurosci. 2008 Nov 12; 9:109. Spencer B, Marr RA, Rockenstein E, Crews L, Adame A, Potkar R, Patrick C, Gage FH, Verma IM, Masliah E. PMID: 19014502; PMCID: PMC2596170.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    319. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):18012-7. Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K. PMID: 19004774; PMCID: PMC2584744.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    320. Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. PLoS Biol. 2008 Nov 11; 6(11):e272. Jessberger S, Aigner S, Clemenson GD, Toni N, Lie DC, Karalay O, Overall R, Kempermann G, Gage FH. PMID: 18998770; PMCID: PMC2581629.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    321. Experts provide insights into emerging field of brain and spine repair. Interview by Bridget M. Kuehn. JAMA. 2008 Sep 03; 300(9):1013-4. Gage FH, Selzer ME. PMID: 18768407.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    322. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. J Biol Chem. 2008 Oct 10; 283(41):27644-27652. Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X. PMID: 18689796; PMCID: PMC2562066.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    323. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nat Neurosci. 2008 Aug; 11(8):901-7. Toni N, Laplagne DA, Zhao C, Lombardi G, Ribak CE, Gage FH, Schinder AF. PMID: 18622400; PMCID: PMC2572641.
      View in: PubMed   Mentions: 330     Fields:    Translation:HumansAnimalsCells
    324. Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nat Neurosci. 2008 Aug; 11(8):888-93. Jessberger S, Toni N, Clemenson GD, Ray J, Gage FH. PMID: 18587391; PMCID: PMC2795354.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    325. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Hum Mol Genet. 2008 Apr 15; 17(R1):R67-75. Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. PMID: 18632700.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    326. Mechanisms and functional implications of adult neurogenesis. Cell. 2008 Feb 22; 132(4):645-60. Zhao C, Deng W, Gage FH. PMID: 18295581.
      View in: PubMed   Mentions: 1317     Fields:    Translation:HumansAnimalsCells
    327. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature. 2008 Feb 21; 451(7181):1004-7. Zhang CL, Zou Y, He W, Gage FH, Evans RM. PMID: 18235445.
      View in: PubMed   Mentions: 252     Fields:    Translation:AnimalsCells
    328. Identification of small molecules from human embryonic stem cells using metabolomics. Stem Cells Dev. 2007 Dec; 16(6):869-82. Cezar GG, Quam JA, Smith AM, Rosa GJ, Piekarczyk MS, Brown JF, Gage FH, Muotri AR. PMID: 18042039.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    329. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell. 2007 Nov; 1(5):515-28. Suh H, Consiglio A, Ray J, Sawai T, D'Amour KA, Gage FH. PMID: 18371391; PMCID: PMC2185820.
      View in: PubMed   Mentions: 369     Fields:    Translation:AnimalsCells
    330. The necessary junk: new functions for transposable elements. Hum Mol Genet. 2007 Oct 15; 16 Spec No. 2:R159-67. Muotri AR, Marchetto MC, Coufal NG, Gage FH. PMID: 17911158.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    331. Mouse erythrocyte tropomodulin in the brain reported by lacZ knocked-in downstream from the E1 promoter. Gene Expr Patterns. 2007 Dec; 8(1):36-46. Yao W, Nathanson J, Lian I, Gage FH, Sung LA. PMID: 17920339.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    332. Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling. J Neurosci. 2007 Aug 29; 27(35):9400-7. Jessberger S, Zhao C, Toni N, Clemenson GD, Li Y, Gage FH. PMID: 17728453; PMCID: PMC6673128.
      View in: PubMed   Mentions: 158     Fields:    Translation:AnimalsCells
    333. Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput Biol. 2007 Oct; 3(10):1951-67. Yeo GW, Xu X, Liang TY, Muotri AR, Carson CT, Coufal NG, Gage FH. PMID: 17967047; PMCID: PMC2041973.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    334. The glycans of stem cells. Curr Opin Chem Biol. 2007 Aug; 11(4):373-80. Lanctot PM, Gage FH, Varki AP. PMID: 17681848; PMCID: PMC2697851.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    335. A novel model for an older remodeler: the BAF swap in neurogenesis. Neuron. 2007 Jul 19; 55(2):171-3. Aigner S, Denli AM, Gage FH. PMID: 17640518.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    336. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J Neurosci. 2007 May 30; 27(22):5967-75. Jessberger S, Nakashima K, Clemenson GD, Mejia E, Mathews E, Ure K, Ogawa S, Sinton CM, Gage FH, Hsieh J. PMID: 17537967; PMCID: PMC6672253.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    337. Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice. J Neurosci. 2007 May 30; 27(22):5869-78. van Praag H, Lucero MJ, Yeo GW, Stecker K, Heivand N, Zhao C, Yip E, Afanador M, Schroeter H, Hammerstone J, Gage FH. PMID: 17537957; PMCID: PMC6672256.
      View in: PubMed   Mentions: 114     Fields:    Translation:Animals
    338. Similar GABAergic inputs in dentate granule cells born during embryonic and adult neurogenesis. Eur J Neurosci. 2007 May; 25(10):2973-81. Laplagne DA, Kamienkowski JE, Espósito MS, Piatti VC, Zhao C, Gage FH, Schinder AF. PMID: 17509085.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    339. Synapse formation on neurons born in the adult hippocampus. Nat Neurosci. 2007 Jun; 10(6):727-34. Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, van Praag H, Martone ME, Ellisman MH, Gage FH. PMID: 17486101.
      View in: PubMed   Mentions: 265     Fields:    Translation:AnimalsCells
    340. LINE-1 retrotransposition in human embryonic stem cells. Hum Mol Genet. 2007 Jul 01; 16(13):1569-77. Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. PMID: 17468180.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    341. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol Dis. 2007 Jul; 27(1):77-89. Smrt RD, Eaves-Egenes J, Barkho BZ, Santistevan NJ, Zhao C, Aimone JB, Gage FH, Zhao X. PMID: 17532643; PMCID: PMC2789309.
      View in: PubMed   Mentions: 123     Fields:    Translation:AnimalsCells
    342. Neprilysin protects neurons against Abeta peptide toxicity. Brain Res. 2007 Jun 04; 1152:191-200. El-Amouri SS, Zhu H, Yu J, Gage FH, Verma IM, Kindy MS. PMID: 17459354; PMCID: PMC2020816.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    343. Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. J Neurosci. 2007 Mar 21; 27(12):3252-9. Tashiro A, Makino H, Gage FH. PMID: 17376985; PMCID: PMC6672473.
      View in: PubMed   Mentions: 220     Fields:    Translation:AnimalsCells
    344. An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5638-43. Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM, Sloan R, Gage FH, Brown TR, Small SA. PMID: 17374720; PMCID: PMC1838482.
      View in: PubMed   Mentions: 516     Fields:    Translation:HumansAnimalsCells
    345. A functional study of miR-124 in the developing neural tube. Genes Dev. 2007 Mar 01; 21(5):531-6. Cao X, Pfaff SL, Gage FH. PMID: 17344415; PMCID: PMC1820895.
      View in: PubMed   Mentions: 168     Fields:    Translation:AnimalsCells
    346. Cortical area size dictates performance at modality-specific behaviors. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):4153-8. Leingärtner A, Thuret S, Kroll TT, Chou SJ, Leasure JL, Gage FH, O'Leary DD. PMID: 17360492; PMCID: PMC1820724.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    347. Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta. J Comp Neurol. 2007 Feb 20; 500(6):1064-75. Suzuki S, Gerhold LM, Böttner M, Rau SW, Dela Cruz C, Yang E, Zhu H, Yu J, Cashion AB, Kindy MS, Merchenthaler I, Gage FH, Wise PM. PMID: 17183542.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    348. Is neurogenesis reparative after status epilepticus? Epilepsia. 2007; 48 Suppl 8:69-71. Parent JM, Jessberger S, Gage FH, Gong C. PMID: 18330005.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    349. Spontaneous fusion and nonclonal growth of adult neural stem cells. Stem Cells. 2007 Apr; 25(4):871-4. Jessberger S, Clemenson GD, Gage FH. PMID: 17185607.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    350. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19546-51. Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. PMID: 17164329; PMCID: PMC1748262.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    351. Integration of new neurons into functional neural networks. J Neurosci. 2006 Nov 22; 26(47):12237-41. Ramirez-Amaya V, Marrone DF, Gage FH, Worley PF, Barnes CA. PMID: 17122048; PMCID: PMC6675440.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    352. Ex vivo and in vivo gene delivery to the brain. Curr Protoc Hum Genet. 2006 Nov; Chapter 13:Unit 13.3. Suhonen J, Ray J, Blömer U, Gage FH, Kaspar B. PMID: 18428389.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    353. Functional convergence of neurons generated in the developing and adult hippocampus. PLoS Biol. 2006 Nov; 4(12):e409. Laplagne DA, Espósito MS, Piatti VC, Morgenstern NA, Zhao C, van Praag H, Gage FH, Schinder AF. PMID: 17121455; PMCID: PMC1637132.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    354. Stem cells: the good, bad and barely in control. Nat Med. 2006 Nov; 12(11):1237-8. Carson CT, Aigner S, Gage FH. PMID: 17088886.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    355. Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol. 2006 Oct 01; 498(4):525-38. Horky LL, Galimi F, Gage FH, Horner PJ. PMID: 16874803; PMCID: PMC2553041.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    356. NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature. 2006 Aug 24; 442(7105):929-33. Tashiro A, Sandler VM, Toni N, Zhao C, Gage FH. PMID: 16906136.
      View in: PubMed   Mentions: 297     Fields:    Translation:AnimalsCells
    357. New regulators in adult neurogenesis and their potential role for repair. Trends Mol Med. 2006 Sep; 12(9):400-5. Jagasia R, Song H, Gage FH, Lie DC. PMID: 16890023.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    358. Therapeutic interventions after spinal cord injury. Nat Rev Neurosci. 2006 Aug; 7(8):628-43. Thuret S, Moon LD, Gage FH. PMID: 16858391.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimals
    359. Functional and morphological effects of NG2 proteoglycan deletion on hippocampal neurogenesis. Exp Neurol. 2006 Nov; 202(1):167-78. Thallmair M, Ray J, Stallcup WB, Gage FH. PMID: 16814771.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    360. Generation of neuronal variability and complexity. Nature. 2006 Jun 29; 441(7097):1087-93. Muotri AR, Gage FH. PMID: 16810244.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    361. Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10294-10299. Suzuki A, Raya Á, Kawakami Y, Morita M, Matsui T, Nakashima K, Gage FH, Rodríguez-Esteban C, Izpisúa Belmonte JC. PMID: 16801560; PMCID: PMC1502451.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    362. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006 Jun; 15(3):407-21. Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K, Gage FH, Zhao X. PMID: 16846377; PMCID: PMC2777811.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    363. Potential role for adult neurogenesis in the encoding of time in new memories. Nat Neurosci. 2006 Jun; 9(6):723-7. Aimone JB, Wiles J, Gage FH. PMID: 16732202.
      View in: PubMed   Mentions: 275     Fields:    Translation:HumansAnimalsCells
    364. Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15; 20(10):1308-20. Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM. PMID: 16702404; PMCID: PMC1472905.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    365. Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification. Nat Clin Pract Cardiovasc Med. 2006 Mar; 3 Suppl 1:S114-22. Suzuki A, Raya A, Kawakami Y, Morita M, Matsui T, Nakashima K, Gage FH, Rodríguez-Esteban C, Izpisúa Belmonte JC. PMID: 16501617.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    366. Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3902-7. Jacobs S, Lie DC, DeCicco KL, Shi Y, DeLuca LM, Gage FH, Evans RM. PMID: 16505366; PMCID: PMC1450163.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    367. Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. J Neurosci. 2006 Feb 22; 26(8):2157-66. Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, Gage FH, Edgerton VR, Tuszynski MH. PMID: 16495442; PMCID: PMC6674802.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    368. Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells. Mol Cell Neurosci. 2006 Mar; 31(3):560-73. Ray J, Gage FH. PMID: 16426857.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    369. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angew Chem Int Ed Engl. 2006 Jan 16; 45(4):591-3. Warashina M, Min KH, Kuwabara T, Huynh A, Gage FH, Schultz PG, Ding S. PMID: 16323231.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    370. Unconventional translation of mammalian LINE-1 retrotransposons. Genes Dev. 2006 Jan 15; 20(2):210-24. Alisch RS, Garcia-Perez JL, Muotri AR, Gage FH, Moran JV. PMID: 16418485; PMCID: PMC1356112.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    371. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2006 Jan 17; 103(3):780-5. Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. PMID: 16407118; PMCID: PMC1325968.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    372. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J Neurosci. 2006 Jan 04; 26(1):3-11. Zhao C, Teng EM, Summers RG, Ming GL, Gage FH. PMID: 16399667; PMCID: PMC6674324.
      View in: PubMed   Mentions: 567     Fields:    Translation:HumansAnimalsCells
    373. Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus. Eur J Neurosci. 2006 Jan; 23(1):83-93. Battista D, Ferrari CC, Gage FH, Pitossi FJ. PMID: 16420418.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    374. Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo. Nat Protoc. 2006; 1(6):3049-55. Tashiro A, Zhao C, Gage FH. PMID: 17406567.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    375. Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci. 2006; 29:77-103. Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. PMID: 16776580.
      View in: PubMed   Mentions: 205     Fields:    Translation:HumansAnimalsCells
    376. Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation. Restor Neurol Neurosci. 2006; 24(3):147-61. Moon LD, Leasure JL, Gage FH, Bunge MB. PMID: 16873970.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    377. In vivo evidence for radial migration of neurons by long-distance somal translocation in the developing ferret visual cortex. Cereb Cortex. 2006 Nov; 16(11):1571-83. Borrell V, Kaspar BK, Gage FH, Callaway EM. PMID: 16357334.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    378. Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18644-8. Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH. PMID: 16352714; PMCID: PMC1317971.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    379. Wnt signalling regulates adult hippocampal neurogenesis. Nature. 2005 Oct 27; 437(7063):1370-5. Lie DC, Colamarino SA, Song HJ, Désiré L, Mira H, Consiglio A, Lein ES, Jessberger S, Lansford H, Dearie AR, Gage FH. PMID: 16251967.
      View in: PubMed   Mentions: 650     Fields:    Translation:AnimalsCells
    380. Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol. 2005 Dec; 17(6):664-71. Hsieh J, Gage FH. PMID: 16226449.
      View in: PubMed   Mentions: 85     Fields:    Translation:Cells
    381. Neuronal and glial cell biology. Curr Opin Neurobiol. 2005 Oct; 15(5):497-9. Gage FH, McAllister AK. PMID: 16143511.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    382. Regulatable acetylcholine-producing fibroblasts enhance cognitive performance. Mol Ther. 2006 Jan; 13(1):175-82. Pizzo DP, Coufal NG, Lortie MJ, Gage FH, Thal LJ. PMID: 16185935.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    383. Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci. 2005 Sep 21; 25(38):8680-5. van Praag H, Shubert T, Zhao C, Gage FH. PMID: 16177036; PMCID: PMC1360197.
      View in: PubMed   Mentions: 801     Fields:    Translation:AnimalsCells
    384. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):14069-74. Cummings BJ, Uchida N, Tamaki SJ, Salazar DL, Hooshmand M, Summers R, Gage FH, Anderson AJ. PMID: 16172374; PMCID: PMC1216836.
      View in: PubMed   Mentions: 285     Fields:    Translation:HumansAnimalsCells
    385. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nat Neurosci. 2005 Oct; 8(10):1343-9. Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, Gage FH, Verma IM, Masliah E. PMID: 16136043.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansAnimalsCells
    386. Targeted expression of IGF-1 in the central nervous system fails to protect mice from experimental autoimmune encephalomyelitis. J Neuroimmunol. 2005 Nov; 168(1-2):40-5. Genoud S, Maricic I, Kumar V, Gage FH. PMID: 16120466.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    387. Proliferation, migration, neuronal differentiation, and long-term survival of new cells in the adult zebrafish brain. J Comp Neurol. 2005 Aug 01; 488(3):290-319. Zupanc GK, Hinsch K, Gage FH. PMID: 15952170.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    388. A small gem with great powers: geminin keeps neural progenitors thriving. Dev Cell. 2005 Aug; 9(2):171-2. Aigner S, Gage FH. PMID: 16054024.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    389. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature. 2005 Jun 16; 435(7044):903-10. Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. PMID: 15959507.
      View in: PubMed   Mentions: 467     Fields:    Translation:HumansAnimalsCells
    390. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19; 46(4):569-79. Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. PMID: 15944126.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    391. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Ann Neurol. 2005 May; 57(5):773-6. Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. PMID: 15852369; PMCID: PMC1351126.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    392. Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis. Ann Neurol. 2005 May; 57(5):649-55. Kaspar BK, Frost LM, Christian L, Umapathi P, Gage FH. PMID: 15852403.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    393. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. J Comp Neurol. 2005 Apr 25; 485(1):1-10. Lein ES, Callaway EM, Albright TD, Gage FH. PMID: 15776443.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    394. Quantitative analysis of gene expression in living adult neural stem cells by gene trapping. Nat Methods. 2005 May; 2(5):363-70. Scheel JR, Ray J, Gage FH, Barlow C. PMID: 15846364.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    395. DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proc Natl Acad Sci U S A. 2005 Apr 19; 102(16):5844-9. Lilley CE, Carson CT, Muotri AR, Gage FH, Weitzman MD. PMID: 15824307; PMCID: PMC556126.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    396. Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. Neuron. 2005 Apr 07; 46(1):37-49. Myers CP, Lewcock JW, Hanson MG, Gosgnach S, Aimone JB, Gage FH, Lee KF, Landmesser LT, Pfaff SL. PMID: 15820692.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    397. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med. 2005 Feb; 11(2):228-32. Martin MJ, Muotri A, Gage F, Varki A. PMID: 15685172.
      View in: PubMed   Mentions: 279     Fields:    Translation:HumansAnimalsCells
    398. The NRSE smRNA specifies the fate of adult hippocampal neural stem cells. Nucleic Acids Symp Ser (Oxf). 2005; (49):87-8. Kuwabara T, Hsieh J, Nakashima K, Warashina M, Taira K, Gage FH. PMID: 17150646.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    399. An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model. Gene Ther. 2004 Dec; 11(23):1713-23. Hashimoto M, Rockenstein E, Mante M, Crews L, Bar-On P, Gage FH, Marr R, Masliah E. PMID: 15483670.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    400. A role for bone marrow-derived cells in the vasculature of noninjured CNS. Blood. 2005 Mar 15; 105(6):2400-2. Galimi F, Summers RG, van Praag H, Verma IM, Gage FH. PMID: 15572598.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    401. Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology. J Neurosci. 2004 Nov 24; 24(47):10642-51. Shihabuddin LS, Numan S, Huff MR, Dodge JC, Clarke J, Macauley SL, Yang W, Taksir TV, Parsons G, Passini MA, Gage FH, Stewart GR. PMID: 15564580; PMCID: PMC6730128.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    402. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16659-64. Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. PMID: 15537713; PMCID: PMC527137.
      View in: PubMed   Mentions: 299     Fields:    Translation:AnimalsCells
    403. Microfabricated platform for studying stem cell fates. Biotechnol Bioeng. 2004 Nov 05; 88(3):399-415. Chin VI, Taupin P, Sanga S, Scheel J, Gage FH, Bhatia SN. PMID: 15486946.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    404. Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A. 2004 Oct 12; 101(41):14835-40. Consiglio A, Gritti A, Dolcetta D, Follenzi A, Bordignon C, Gage FH, Vescovi AL, Naldini L. PMID: 15466696; PMCID: PMC522006.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    405. Epigenetic control of neural stem cell fate. Curr Opin Genet Dev. 2004 Oct; 14(5):461-9. Hsieh J, Gage FH. PMID: 15380235.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    406. A hypothesis about the role of adult neurogenesis in hippocampal function. Physiology (Bethesda). 2004 Oct; 19:253-61. Schinder AF, Gage FH. PMID: 15381753.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    407. Optimizing donor heart outcome after prolonged storage with endothelial function analysis and continuous perfusion. Ann Thorac Surg. 2004 Oct; 78(4):1362-70;; discussion 1362-70. Poston RS, Gu J, Prastein D, Gage F, Hoffman JW, Kwon M, Azimzadeh A, Pierson RN, Griffith BP. PMID: 15464500.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    408. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 2004 Jul 15; 430(6997):350-6. Wurmser AE, Nakashima K, Summers RG, Toni N, D'Amour KA, Lie DC, Gage FH. PMID: 15254537.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    409. Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector. Brain Res Mol Brain Res. 2004 Jul 05; 126(1):1-13. Pizzo DP, Paban V, Coufal NG, Gage FH, Thal LJ. PMID: 15207910.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    410. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. J Neurosci. 2004 Jun 16; 24(24):5459-66. Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK. PMID: 15201317; PMCID: PMC6729318.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    411. Structural plasticity of the adult brain. Dialogues Clin Neurosci. 2004 Jun; 6(2):135-41. Gage FH. PMID: 22034393; PMCID: PMC3181802.
      View in: PubMed   Mentions: 6     Fields:    
    412. Unbiased characterization of high-density oligonucleotide microarrays using probe-level statistics. J Neurosci Methods. 2004 May 30; 135(1-2):27-33. Aimone JB, Gage FH. PMID: 15020086.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    413. Neuroscience. Cellular interactions in the stem cell niche. Science. 2004 May 28; 304(5675):1253-5. Wurmser AE, Palmer TD, Gage FH. PMID: 15166350.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    414. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. J Neurosci. 2004 Apr 14; 24(15):3879-89. Lein ES, Zhao X, Gage FH. PMID: 15084669; PMCID: PMC6729356.
      View in: PubMed   Mentions: 133     Fields:    Translation:Animals
    415. Functional significance of adult neurogenesis. Curr Opin Neurobiol. 2004 Apr; 14(2):186-91. Kempermann G, Wiskott L, Gage FH. PMID: 15082323.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    416. Novel neuronal phenotypes from neural progenitor cells. J Neurosci. 2004 Mar 24; 24(12):2886-97. Markakis EA, Palmer TD, Randolph-Moore L, Rakic P, Gage FH. PMID: 15044527; PMCID: PMC3242437.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    417. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell. 2004 Mar 19; 116(6):779-93. Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH. PMID: 15035981.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansAnimalsCells
    418. IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J Cell Biol. 2004 Jan 05; 164(1):111-22. Hsieh J, Aimone JB, Kaspar BK, Kuwabara T, Nakashima K, Gage FH. PMID: 14709544; PMCID: PMC2171962.
      View in: PubMed   Mentions: 137     Fields:    Translation:AnimalsCells
    419. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature. 2004 Jan 01; 427(6969):78-83. Shi Y, Chichung Lie D, Taupin P, Nakashima K, Ray J, Yu RT, Gage FH, Evans RM. PMID: 14702088.
      View in: PubMed   Mentions: 193     Fields:    Translation:AnimalsCells
    420. Embryonic stem cells: staying plastic on plastic. Nat Med. 2004 Jan; 10(1):23-4. Nakashima K, Colamarino S, Gage FH. PMID: 14702626.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    421. Neurogenesis and neuroadaptation. Neuromolecular Med. 2004; 5(1):1-9. Schaffer DV, Gage FH. PMID: 15001808.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    422. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annu Rev Pharmacol Toxicol. 2004; 44:399-421. Lie DC, Song H, Colamarino SA, Ming GL, Gage FH. PMID: 14744252.
      View in: PubMed   Mentions: 197     Fields:    Translation:HumansAnimalsCells
    423. Neprilysin regulates amyloid Beta peptide levels. J Mol Neurosci. 2004; 22(1-2):5-11. Marr RA, Guan H, Rockenstein E, Kindy M, Gage FH, Verma I, Masliah E, Hersh LB. PMID: 14742905.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    424. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience. 2004; 124(1):71-9. Farmer J, Zhao X, van Praag H, Wodtke K, Gage FH, Christie BR. PMID: 14960340.
      View in: PubMed   Mentions: 266     Fields:    Translation:AnimalsCells
    425. Vibrating in the background. Nat Genet. 2003 Nov; 35(3):205-7. Muotri AR, Gage FH. PMID: 14593403.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    426. Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running. Behav Neurosci. 2003 Oct; 117(5):1006-16. Rhodes JS, van Praag H, Jeffrey S, Girard I, Mitchell GS, Garland T, Gage FH. PMID: 14570550.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    427. Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats. Exp Neurol. 2003 Oct; 183(2):653-64. Dziewczapolski G, Lie DC, Ray J, Gage FH, Shults CW. PMID: 14552907.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    428. Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. J Neurosci. 2003 Sep 24; 23(25):8706-12. Arvanian VL, Horner PJ, Gage FH, Mendell LM. PMID: 14507970; PMCID: PMC6740423.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    429. IGF-I has a direct proliferative effect in adult hippocampal progenitor cells. Mol Cell Neurosci. 2003 Sep; 24(1):23-40. Aberg MA, Aberg ND, Palmer TD, Alborn AM, Carlsson-Skwirut C, Bang P, Rosengren LE, Olsson T, Gage FH, Eriksson PS. PMID: 14550766.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    430. Brain, repair yourself. Sci Am. 2003 Sep; 289(3):46-53. Gage FH. PMID: 12951827.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    431. Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells. Proc Natl Acad Sci U S A. 2003 Sep 30; 100 Suppl 1:11866-72. D'Amour KA, Gage FH. PMID: 12923297; PMCID: PMC304100.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    432. Stem cells at the dawn of the 21st century. Proc Natl Acad Sci U S A. 2003 Sep 30; 100 Suppl 1:11817-8. Gage FH, Verma IM. PMID: 12915737; PMCID: PMC304091.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    433. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science. 2003 Aug 08; 301(5634):839-42. Kaspar BK, Lladó J, Sherkat N, Rothstein JD, Gage FH. PMID: 12907804.
      View in: PubMed   Mentions: 301     Fields:    Translation:AnimalsCells
    434. Acetylcholine-secreting cells improve age-induced memory deficits. Mol Ther. 2003 Jul; 8(1):51-61. Dickinson-Anson H, Winkler J, Fisher LJ, Song HJ, Poo Mm, Gage FH. PMID: 12842428.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    435. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. J Neurosci. 2003 Jun 15; 23(12):5031-40. South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, Woolf CJ, Heinemann SF, Inturrisi CE. PMID: 12832526; PMCID: PMC6741202.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    436. An inbred 129SvEv GFPCre transgenic mouse that deletes loxP-flanked genes in all tissues. Nucleic Acids Res. 2003 May 15; 31(10):e57. Scheel JR, Garrett LJ, Allen DM, Carter TA, Randolph-Moore L, Gambello MJ, Gage FH, Wynshaw-Boris A, Barlow C. PMID: 12736323; PMCID: PMC156060.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    437. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6777-82. Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. PMID: 12748381; PMCID: PMC164523.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    438. Stem cells. Setting standards for human embryonic stem cells. Science. 2003 May 09; 300(5621):913-6. Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. PMID: 12738841.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    439. Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. Eur J Neurosci. 2003 May; 17(10):2042-6. Brown J, Cooper-Kuhn CM, Kempermann G, Van Praag H, Winkler J, Gage FH, Kuhn HG. PMID: 12786970.
      View in: PubMed   Mentions: 254     Fields:    Translation:AnimalsCells
    440. Expression of cytokines by multipotent neural progenitor cells. Cytokine. 2003 May; 22(3-4):101-6. Klassen HJ, Imfeld KL, Kirov II, Tai L, Gage FH, Young MJ, Berman MA. PMID: 12849709.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    441. The immunological properties of adult hippocampal progenitor cells. Vision Res. 2003 Apr; 43(8):947-56. Klassen H, Imfeld KL, Ray J, Young MJ, Gage FH, Berman MA. PMID: 12668064.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    442. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. J Neurosci. 2003 Mar 15; 23(6):1992-6. Marr RA, Rockenstein E, Mukherjee A, Kindy MS, Hersh LB, Gage FH, Verma IM, Masliah E. PMID: 12657655; PMCID: PMC6742010.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    443. Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J Neurosci. 2003 Jan 15; 23(2):539-49. Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee KF. PMID: 12533614; PMCID: PMC6741871.
      View in: PubMed   Mentions: 89     Fields: