Srinivasan Ramachandran

Title(s)	RSCH DATA ANL 3, Bioengineering
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease. Alzheimers Res Ther. 2025 Jan 04; 17(1):5. Valdes P, Caldwell AB, Liu Q, Fitzgerald MQ, Ramachandran S, Karch CM, Dominantly Inherited Alzheimer Network (DIAN), Galasko DR, Yuan SH, Wagner SL, Subramaniam S. PMID: 39754192; PMCID: PMC11699654.

View in: PubMed Mentions: Fields:
Neu Neurology
Translation:Humans Cells
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease. Mol Brain. 2023 Nov 03; 16(1):75. Valdes P, Henry KW, Fitzgerald MQ, Muralidharan K, Caldwell AB, Ramachandran S, Goldstein LSB, Mobley WC, Galasko DR, Subramaniam S. PMID: 37924159; PMCID: PMC10623777.

View in: PubMed Mentions: Fields:
Bra Brain Mol Molecular Biology
Translation:Humans Cells
Endotype Characterization Reveals Mechanistic Differences Across Brain Regions in Sporadic Alzheimer's Disease. J Alzheimers Dis Rep. 2023; 7(1):957-972. Patel AO, Caldwell AB, Ramachandran S, Subramaniam S. PMID: 37849634; PMCID: PMC10578327.

View in: PubMed Mentions: 2
MetGENE: gene-centric metabolomics information retrieval tool. Gigascience. 2022 12 28; 12. Srinivasan S, Maurya MR, Ramachandran S, Fahy E, Subramaniam S. PMID: 37983749; PMCID: PMC10659118.

View in: PubMed Mentions: 1 Fields:
Com Computational Biology Gen Genetics
Transcriptomic profiling of sporadic Alzheimer's disease patients. Mol Brain. 2022 10 12; 15(1):83. Caldwell AB, Anantharaman BG, Ramachandran S, Nguyen P, Liu Q, Trinh I, Galasko DR, Desplats PA, Wagner SL, Subramaniam S. PMID: 36224601; PMCID: PMC9559068.

View in: PubMed Mentions: 11 Fields:
Bra Brain Mol Molecular Biology
Translation:Humans Cells
ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease. Exp Mol Med. 2022 06; 54(6):777-787. Azad P, Caldwell AB, Ramachandran S, Spann NJ, Akbari A, Villafuerte FC, Bermudez D, Zhao H, Poulsen O, Zhou D, Bafna V, Subramaniam S, Haddad GG. PMID: 35672450; PMCID: PMC9256584.

View in: PubMed Mentions: 9 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Humans Cells
Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress. Front Cell Dev Biol. 2021; 9:702974. Raghunandan S, Ramachandran S, Ke E, Miao Y, Lal R, Chen ZB, Subramaniam S. PMID: 34595164; PMCID: PMC8476872.

View in: PubMed Mentions: 5
Direct DNA Methylation Profiling with an Electric Biosensor. ACS Nano. 2020 06 23; 14(6):6743-6751. Ban DK, Liu Y, Wang Z, Ramachandran S, Sarkar N, Shi Z, Liu W, Karkisaval AG, Martinez-Loran E, Zhang F, Glinsky G, Bandaru PR, Fan C, Lal R. PMID: 32407064.

View in: PubMed Mentions: 5 Fields:
Nan Nanotechnology
Translation:Humans Cells
Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics. Nanomedicine. 2016 11; 12(8):2331-2340. Gillman AL, Lee J, Ramachandran S, Capone R, Gonzalez T, Wrasidlo W, Masliah E, Lal R. PMID: 27335341; PMCID: PMC5116404.

View in: PubMed Mentions: Fields:
Bio Biotechnology Nan Nanotechnology
Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies. Biochemistry. 2015 Dec 22; 54(50):7320-5. Patel N, Ramachandran S, Azimov R, Kagan BL, Lal R. PMID: 26575330; PMCID: PMC4690196.

View in: PubMed Mentions: 23 Fields:
Bio Biochemistry
Role of the fast kinetics of pyroglutamate-modified amyloid-β oligomers in membrane binding and membrane permeability. Biochemistry. 2014 Jul 22; 53(28):4704-14. Lee J, Gillman AL, Jang H, Ramachandran S, Kagan BL, Nussinov R, Teran Arce F. PMID: 24950761; PMCID: PMC4215883.

View in: PubMed Mentions: 21 Fields:
Bio Biochemistry
Translation:Humans Cells
Activity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) pores. J Phys Chem B. 2014 Jul 03; 118(26):7335-44. Gillman AL, Jang H, Lee J, Ramachandran S, Kagan BL, Nussinov R, Teran Arce F. PMID: 24922585; PMCID: PMC4096221.

View in: PubMed Mentions: 20 Fields:
Che Chemistry
Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. Sci Rep. 2014 Mar 21; 4:4424. Ramachandran S, Arce FT, Patel NR, Quist AP, Cohen DA, Lal R. PMID: 24651823; PMCID: PMC3961736.

View in: PubMed Mentions: 3 Fields:
Sci Science
Translation:Animals Cells
High performance, LED powered, waveguide based total internal reflection microscopy. Sci Rep. 2013; 3:2133. Ramachandran S, Cohen DA, Quist AP, Lal R. PMID: 23823601; PMCID: PMC3701166.

View in: PubMed Mentions: 15 Fields:
Sci Science
Translation:Animals Cells
Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations. Biochemistry. 2012 Apr 10; 51(14):3031-8. Connelly L, Jang H, Arce FT, Ramachandran S, Kagan BL, Nussinov R, Lal R. PMID: 22413858; PMCID: PMC7512688.

View in: PubMed Mentions: 20 Fields:
Bio Biochemistry
Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology. J Phys Chem B. 2012 Feb 09; 116(5):1728-35. Connelly L, Jang H, Arce FT, Capone R, Kotler SA, Ramachandran S, Kagan BL, Nussinov R, Lal R. PMID: 22217000; PMCID: PMC4342054.

View in: PubMed Mentions: 34 Fields:
Che Chemistry
DNA zipper-based tweezers. Langmuir. 2012 Jan 10; 28(1):534-40. Landon PB, Ramachandran S, Gillman A, Gidron T, Yoon D, Lal R. PMID: 21875130.

View in: PubMed Mentions: 5 Fields:
Che Chemistry
Translation:Cells
Potential role of atomic force microscopy in systems biology. Wiley Interdiscip Rev Syst Biol Med. 2011 Nov-Dec; 3(6):702-16. Ramachandran S, Teran Arce F, Lal R. PMID: 21766465; PMCID: PMC4353599.

View in: PubMed Mentions: 1 Fields:
Com Computational Biology Med Medical Informatics
Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation. Soft Matter. 2011 May 09; 7(11):5267-5273. Arce FT, Jang H, Ramachandran S, Landon PB, Nussinov R, Lal R. PMID: 21918653; PMCID: PMC3170770.

View in: PubMed Mentions: 14 Fields:
Bio Biochemistry Che Chemistry
Multidimensional atomic force microscopy: a versatile novel technology for nanopharmacology research. AAPS J. 2010 Dec; 12(4):716-28. Lal R, Ramachandran S, Arnsdorf MF. PMID: 20957528; PMCID: PMC2976997.

View in: PubMed Mentions: 9 Fields:
Dru Drug Therapy Pha Pharmacology
Scope of atomic force microscopy in the advancement of nanomedicine. Indian J Exp Biol. 2010 Oct; 48(10):1020-36. Ramachandran S, Lal R. PMID: 21299045.

View in: PubMed Mentions: 1 Fields:
Bio Biology
Translation:Humans Animals