Ronald Thomas

Title(s)Professor, Herbert Wertheim School of Public Health & Human Longevity Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Dr. Thomas is a Biostatistician with research interests in the following areas: Clinical Trials Design, Analysis of Longitudinal Clinical Trial Data, Visualization software, Clinical Trials Data Capture Software and Discrete Math Algorithms.

    Collapse Research 
    Collapse Research Activities and Funding
    Alzheimer's Disease Cooperative Study
    NIH U19AG010483Jul 1, 1997 - Feb 28, 2021
    Role: Co-Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with early Alzheimer's Disease. Alzheimers Res Ther. 2024 07 05; 16(1):151. Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas RG, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. PMID: 38970127; PMCID: PMC11225352.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    2. Increased [18F]Fluorodeoxyglucose Uptake in the Left Pallidum in Military Veterans with Blast-Related Mild Traumatic Brain Injury: Potential as an Imaging Biomarker and Mediation with Executive Dysfunction and Cognitive Impairment. J Neurotrauma. 2024 07; 41(13-14):1578-1596. Terry G, Pagulayan KF, Muzi M, Mayer C, Murray DR, Schindler AG, Richards TL, McEvoy C, Crabtree A, McNamara C, Means G, Muench P, Powell JR, Mihalik JP, Thomas RG, Raskind MA, Peskind ER, Meabon JS. PMID: 38661540; PMCID: PMC11339557.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Longitudinal Sleep Patterns and Cognitive Impairment in Older Adults. JAMA Netw Open. 2023 12 01; 6(12):e2346006. Keil SA, Schindler AG, Wang MX, Piantino J, Silbert LC, Elliott JE, Werhane ML, Thomas RG, Willis S, Lim MM, Iliff JJ. PMID: 38048131; PMCID: PMC10696486.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. A randomized controlled clinical trial of prazosin for alcohol use disorder in active duty soldiers: Predictive effects of elevated cardiovascular parameters. Alcohol Clin Exp Res (Hoboken). 2023 02; 47(2):348-360. Raskind MA, Williams T, Holmes H, Hart K, Crews L, Poupore EL, Thomas RG, Darnell J, Daniels C, Goke K, Hendrickson R, Terry G, Mayer C, Simpson T, Saxon A, Rasmussen D, Peskind ER. PMID: 36809662.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial. Alzheimers Dement. 2023 05; 19(5):1938-1946. Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, Protas H, Thomas RG, Chen K, Su Y, Boker C, Mastroeni D, Alvarez S, Quiroz YT, Langbaum JB, Sink KM, Lopera F, Tariot PN, API ADAD Colombia Trial Group. PMID: 36373344; PMCID: PMC10262848.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. T2 Protect AD: Achieving a rapid recruitment timeline in a multisite clinical trial for individuals with mild to moderate Alzheimer's disease. Alzheimers Dement (N Y). 2022; 8(1):e12265. Shadyab AH, LaCroix AZ, Matthews G, Bennett D, Shadyab AA, Tan D, Thomas RG, Mason J, Lopez A, Askew B, Donahue L, Kaplita S, Qureshi IA, Huisa B, Feldman HH, Alzheimer's Disease Cooperative Study T2 Protect AD Study Group. PMID: 35310528; PMCID: PMC8919121.
      View in: PubMed   Mentions: 2  
    7. Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial. Alzheimers Dement. 2022 11; 18(11):2272-2282. Vila-Castelar C, Tariot PN, Sink KM, Clayton D, Langbaum JB, Thomas RG, Chen Y, Su Y, Chen K, Hu N, Giraldo-Chica M, Tobón C, Acosta-Baena N, Luna E, Londoño M, Ospina P, Tirado V, Muñoz C, Henao E, Bocanegra Y, Alvarez S, Rios-Romenets S, Ghisays V, Goradia D, Lee W, Luo J, Malek-Ahmadi MH, Protas HD, Lopera F, Reiman EM, Quiroz YT, API ADAD Colombia Trial Group. PMID: 35103388; PMCID: PMC9339586.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    8. Markers of Cerebrovascular Injury, Inflammation, and Plasma Lipids Are Associated with Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Cognitively Normal Persons. J Alzheimers Dis. 2022; 86(2):813-826. Jansson D, Wang M, Thomas RG, Erickson MA, Peskind ER, Li G, Iliff J. PMID: 35124650; PMCID: PMC10010435.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Impact of potential modifications to Alzheimer's disease clinical trials in response to disruption by COVID-19: a simulation study. Alzheimers Res Ther. 2021 12 20; 13(1):201. Schneider LS, Qiu Y, Thomas RG, Evans C, Jacobs DM, Jin S, Kaye JA, LaCroix AZ, Messer K, Salmon DP, Sano M, Schafer K, Feldman HH. PMID: 34930444; PMCID: PMC8686345.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    10. Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial. Alzheimers Dement. 2021 11; 17(11):1808-1817. Shadyab AH, LaCroix AZ, Feldman HH, van Dyck CH, Okonkwo OC, Tam SP, Fairchild JK, Welsh-Bohmer KA, Matthews G, Bennett D, Shadyab AA, Schafer KA, Morrison RH, Kipperman SA, Mason J, Tan D, Thomas RG, Cotman CW, Baker LD, ADCS EXERT Study Group. PMID: 34297895; PMCID: PMC9292825.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer's disease-causing Presenilin-1 E280A mutation carriers. Neuroimage Clin. 2021; 31:102749. Ghisays V, Lopera F, Goradia DD, Protas HD, Malek-Ahmadi MH, Chen Y, Devadas V, Luo J, Lee W, Baena A, Bocanegra Y, Guzmán-Vélez E, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Hu N, Clayton D, Thomas RG, Alvarez S, Espinosa A, Acosta-Baena N, Giraldo MM, Rios-Romenets S, Langbaum JB, Chen K, Su Y, Tariot PN, Quiroz YT, Reiman EM, API ADAD Colombia Trial Group. PMID: 34252876; PMCID: PMC8278433.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    12. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nat Med. 2021 Jul; 27(7):1187-1196. Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Cruchaga C, Goate AA, Perrin RJ, Xiong C, Li Y, Morris JC, Snider BJ, Mummery C, Surti GM, Hannequin D, Wallon D, Berman SB, Lah JJ, Jimenez-Velazquez IZ, Roberson ED, van Dyck CH, Honig LS, Sánchez-Valle R, Brooks WS, Gauthier S, Galasko DR, Masters CL, Brosch JR, Hsiung GR, Jayadev S, Formaglio M, Masellis M, Clarnette R, Pariente J, Dubois B, Pasquier F, Jack CR, Koeppe R, Snyder PJ, Aisen PS, Thomas RG, Berry SM, Wendelberger BA, Andersen SW, Holdridge KC, Mintun MA, Yaari R, Sims JR, Baudler M, Delmar P, Doody RS, Fontoura P, Giacobino C, Kerchner GA, Bateman RJ, Dominantly Inherited Alzheimer Network–Trials Unit. PMID: 34155411; PMCID: PMC8988051.
      View in: PubMed   Mentions: 126     Fields:    Translation:Humans
    13. Rasagiline effects on glucose metabolism, cognition, and tau in Alzheimer's dementia. Alzheimers Dement (N Y). 2021; 7(1):e12106. Matthews DC, Ritter A, Thomas RG, Andrews RD, Lukic AS, Revta C, Kinney JW, Tousi B, Leverenz JB, Fillit H, Zhong K, Feldman HH, Cummings J. PMID: 33614888; PMCID: PMC7882538.
      View in: PubMed   Mentions: 19  
    14. Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS-Cog-Exec. Alzheimers Dement (N Y). 2020; 6(1):e12059. Jacobs DM, Thomas RG, Salmon DP, Jin S, Feldman HH, Cotman CW, Baker LD, Alzheimer's Disease Cooperative Study EXERT Study Group, Alzheimer's Disease Neuroimaging Initiative. PMID: 32995469; PMCID: PMC7507362.
      View in: PubMed   Mentions: 8  
    15. Optimizing Aggregated N-Of-1 Trial Designs for Predictive Biomarker Validation: Statistical Methods and Theoretical Findings. Front Digit Health. 2020; 2:13. Hendrickson RC, Thomas RG, Schork NJ, Raskind MA. PMID: 34713026; PMCID: PMC8521797.
      View in: PubMed   Mentions: 3  
    16. The Alzheimer's Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer's disease. Alzheimers Res Ther. 2020 05 27; 12(1):66. Langbaum JB, Ellison NN, Caputo A, Thomas RG, Langlois C, Riviere ME, Graf A, Lopez Lopez C, Reiman EM, Tariot PN, Hendrix SB. PMID: 32460855; PMCID: PMC7254761.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial. Alzheimers Dement. 2020 07; 16(7):1023-1030. Rios-Romenets S, Lopera F, Sink KM, Hu N, Lian Q, Guthrie H, Smith J, Cho W, Mackey H, Langbaum JB, Thomas RG, Giraldo-Chica M, Tobon C, Acosta-Baena N, Muñoz C, Ospina P, Tirado V, Henao E, Bocanegra Y, Chen K, Su Y, Goradia D, Thiyyagura P, VanGilder PS, Luo J, Ghisays V, Lee W, Malek-Ahmadi MH, Protas HD, Chen Y, Quiroz YT, Reiman EM, Tariot PN, the API ADAD Colombia Trial Group. PMID: 32418361; PMCID: PMC7819133.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    18. Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial. JAMA Neurol. 2019 Nov 01; 76(11):1330-1339. Schneider LS, Thomas RG, Hendrix S, Rissman RA, Brewer JB, Salmon DP, Oltersdorf T, Okuda T, Feldman HH, Alzheimer’s Disease Cooperative Study TCAD Study Group. PMID: 31282954; PMCID: PMC6618817.
      View in: PubMed   Mentions: 11     Fields:    
    19. Low-dose ladostigil for mild cognitive impairment: A phase 2 placebo-controlled clinical trial. Neurology. 2019 10 08; 93(15):e1474-e1484. Schneider LS, Geffen Y, Rabinowitz J, Thomas RG, Schmidt R, Ropele S, Weinstock M, Ladostigil Study Group. PMID: 31492718; PMCID: PMC7010322.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCTClinical Trials
    20. The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease. Alzheimers Dement (N Y). 2019; 5:216-227. Lopez Lopez C, Tariot PN, Caputo A, Langbaum JB, Liu F, Riviere ME, Langlois C, Rouzade-Dominguez ML, Zalesak M, Hendrix S, Thomas RG, Viglietta V, Lenz R, Ryan JM, Graf A, Reiman EM. PMID: 31211217; PMCID: PMC6562315.
      View in: PubMed   Mentions: 44  
    21. A randomized clinical trial to evaluate home-based assessment of people over 75 years old. Alzheimers Dement. 2019 05; 15(5):615-624. Sano M, Zhu CW, Kaye J, Mundt JC, Hayes TL, Ferris S, Thomas RG, Sun CK, Jiang Y, Donohue MC, Schneider LS, Egelko S, Aisen PS, Feldman HH, Alzheimer Disease Cooperative Study Investigators. PMID: 30872114.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Memantine and Acetylcholinesterase Inhibitor Use in Alzheimer's Disease Clinical Trials: Potential for Confounding by Indication. J Alzheimers Dis. 2019; 67(2):707-713. Huisa BN, Thomas RG, Jin S, Oltersdorf T, Taylor C, Feldman HH. PMID: 30636733.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial. JAMA Neurol. 2018 07 01; 75(7):834-841. Rafii MS, Tuszynski MH, Thomas RG, Barba D, Brewer JB, Rissman RA, Siffert J, Aisen PS, AAV2-NGF Study Team. PMID: 29582053; PMCID: PMC5885277.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    24. The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort. Alzheimers Dement (N Y). 2018; 4:150-160. Tariot PN, Lopera F, Langbaum JB, Thomas RG, Hendrix S, Schneider LS, Rios-Romenets S, Giraldo M, Acosta N, Tobon C, Ramos C, Espinosa A, Cho W, Ward M, Clayton D, Friesenhahn M, Mackey H, Honigberg L, Sanabria Bohorquez S, Chen K, Walsh T, Langlois C, Reiman EM, Alzheimer's Prevention Initiative. PMID: 29955659; PMCID: PMC6021543.
      View in: PubMed   Mentions: 69  
    25. A phase 3 trial of IV immunoglobulin for Alzheimer disease. Neurology. 2017 May 02; 88(18):1768-1775. Relkin NR, Thomas RG, Rissman RA, Brewer JB, Rafii MS, van Dyck CH, Jack CR, Sano M, Knopman DS, Raman R, Szabo P, Gelmont DM, Fritsch S, Aisen PS, Alzheimer's Disease Cooperative Study. PMID: 28381506; PMCID: PMC5409846.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCTClinical Trials
    26. Randomized controlled trials in mild cognitive impairment: Sources of variability. Neurology. 2017 May 02; 88(18):1751-1758. Petersen RC, Thomas RG, Aisen PS, Mohs RC, Carrillo MC, Albert MS, Alzheimer's Disease Neuroimaging Initiative (ADNI) and Foundation for NIH (FNIH) Biomarkers Consorti. PMID: 28381516; PMCID: PMC5409843.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    27. Demonstration of safety of intravenous immunoglobulin in geriatric patients in a long-term, placebo-controlled study of Alzheimer's disease. Alzheimers Dement (N Y). 2016 Jun; 2(2):131-139. Gelmont D, Thomas RG, Britt J, Dyck-Jones JA, Doralt J, Fritsch S, Brewer JB, Rissman RA, Aisen P. PMID: 29067300; PMCID: PMC5644268.
      View in: PubMed   Mentions: 1  
    28. Longitudinal decline in mild-to-moderate Alzheimer's disease: Analyses of placebo data from clinical trials. Alzheimers Dement. 2016 05; 12(5):598-603. Thomas RG, Albert M, Petersen RC, Aisen PS. PMID: 26917500.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Neurology. 2015 Oct 20; 85(16):1383-91. Turner RS, Thomas RG, Craft S, van Dyck CH, Mintzer J, Reynolds BA, Brewer JB, Rissman RA, Raman R, Aisen PS, Alzheimer's Disease Cooperative Study. PMID: 26362286; PMCID: PMC4626244.
      View in: PubMed   Mentions: 261     Fields:    Translation:HumansCTClinical Trials
    30. Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimers Res Ther. 2015; 7(1):36. Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS, Alzheimer’s Disease Cooperative Study. PMID: 26064192; PMCID: PMC4461930.
      View in: PubMed   Mentions: 16     Fields:    
    31. Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials. Alzheimers Dement. 2015 Sep; 11(9):1069-79. Donohue MC, Moghadam SH, Roe AD, Sun CK, Edland SD, Thomas RG, Petersen RC, Sano M, Galasko D, Aisen PS, Rissman RA. PMID: 25301682; PMCID: PMC4387108.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    32. The preclinical Alzheimer cognitive composite: measuring amyloid-related decline. JAMA Neurol. 2014 Aug; 71(8):961-70. Donohue MC, Sperling RA, Salmon DP, Rentz DM, Raman R, Thomas RG, Weiner M, Aisen PS, Australian Imaging, Biomarkers, and Lifestyle Flagship Study of Ageing, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Cooperative Study. PMID: 24886908; PMCID: PMC4439182.
      View in: PubMed   Mentions: 395     Fields:    Translation:Humans
    33. Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease. Neurology. 2014 Apr 29; 82(17):1536-42. Galasko D, Bell J, Mancuso JY, Kupiec JW, Sabbagh MN, van Dyck C, Thomas RG, Aisen PS, Alzheimer's Disease Cooperative Study. PMID: 24696507; PMCID: PMC4011464.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCTClinical Trials
    34. Estimating long-term multivariate progression from short-term data. Alzheimers Dement. 2014 Oct; 10(5 Suppl):S400-10. Donohue MC, Jacqmin-Gadda H, Le Goff M, Thomas RG, Raman R, Gamst AC, Beckett LA, Jack CR, Weiner MW, Dartigues JF, Aisen PS, Alzheimer's Disease Neuroimaging Initiative. PMID: 24656849; PMCID: PMC4169767.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    35. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med. 2014 Jan 23; 370(4):311-21. Doody RS, Thomas RG, Farlow M, Iwatsubo T, Vellas B, Joffe S, Kieburtz K, Raman R, Sun X, Aisen PS, Siemers E, Liu-Seifert H, Mohs R, Alzheimer's Disease Cooperative Study Steering Committee, Solanezumab Study Group. PMID: 24450890.
      View in: PubMed   Mentions: 709     Fields:    Translation:HumansCTClinical Trials
    36. A phase 3 trial of semagacestat for treatment of Alzheimer's disease. N Engl J Med. 2013 Jul 25; 369(4):341-50. Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, Kieburtz K, He F, Sun X, Thomas RG, Aisen PS, Alzheimer's Disease Cooperative Study Steering Committee, Siemers E, Sethuraman G, Mohs R, Semagacestat Study Group. PMID: 23883379.
      View in: PubMed   Mentions: 482     Fields:    Translation:HumansCTClinical Trials
    37. Age and apolipoprotein E genotype influence rate of cognitive decline in nondemented elderly. Neuropsychology. 2013 Jul; 27(4):391-401. Salmon DP, Ferris SH, Thomas RG, Sano M, Cummings JL, Sperling RA, Petersen RC, Aisen PS. PMID: 23876113; PMCID: PMC3831285.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    38. Establishing the psychometric underpinning of cognition measures for clinical trials of Alzheimer's disease and its precursors: a new approach. Alzheimers Dement. 2013 Feb; 9(1 Suppl):S56-60. Posner HB, Cano S, Carrillo MC, Selnes O, Stern Y, Thomas RG, Zajicek J, Hobart J, Alzheimer's Disease Neuroimaging Initiative. PMID: 23391006.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Arch Neurol. 2012 Jul; 69(7):836-41. Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P, Alzheimer’s Disease Cooperative Study. PMID: 22431837; PMCID: PMC3661272.
      View in: PubMed   Mentions: 164     Fields:    Translation:Humans
    40. Incidence of new-onset seizures in mild to moderate Alzheimer disease. Arch Neurol. 2012 Mar; 69(3):368-72. Irizarry MC, Jin S, He F, Emond JA, Raman R, Thomas RG, Sano M, Quinn JF, Tariot PN, Galasko DR, Ishihara LS, Weil JG, Aisen PS. PMID: 22410444; PMCID: PMC3622046.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    41. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiative, Pediatric Imaging, Neurocognition, and Genetics Study, Weiner M, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, et al. PMID: 22343285; PMCID: PMC3309762.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    42. Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease. Arch Gen Psychiatry. 2011 Aug; 68(8):853-61. Tariot PN, Schneider LS, Cummings J, Thomas RG, Raman R, Jakimovich LJ, Loy R, Bartocci B, Fleisher A, Ismail MS, Porsteinsson A, Weiner M, Jack CR, Thal L, Aisen PS, Alzheimer's Disease Cooperative Study Group. PMID: 21810649; PMCID: PMC7003728.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    43. Dietary self-monitoring and its impact on weight loss in overweight children. Int J Pediatr Obes. 2011 Aug; 6(3-4):197-205. Mockus DS, Macera CA, Wingard DL, Peddecord M, Thomas RG, Wilfley DE. PMID: 21722068; PMCID: PMC3788598.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    44. Adding delayed recall to the Alzheimer Disease Assessment Scale is useful in studies of mild cognitive impairment but not Alzheimer disease. Alzheimer Dis Assoc Disord. 2011 Apr-Jun; 25(2):122-7. Sano M, Raman R, Emond J, Thomas RG, Petersen R, Schneider LS, Aisen PS. PMID: 20921876; PMCID: PMC3526369.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    45. Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial. JAMA. 2010 Nov 03; 304(17):1903-11. Quinn JF, Raman R, Thomas RG, Yurko-Mauro K, Nelson EB, Van Dyck C, Galvin JE, Emond J, Jack CR, Weiner M, Shinto L, Aisen PS. PMID: 21045096; PMCID: PMC3259852.
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    46. Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans. Alzheimers Dement. 2010 May; 6(3):239-46. Aisen PS, Petersen RC, Donohue MC, Gamst A, Raman R, Thomas RG, Walter S, Trojanowski JQ, Shaw LM, Beckett LA, Jack CR, Jagust W, Toga AW, Saykin AJ, Morris JC, Green RC, Weiner MW, Alzheimer's Disease Neuroimaging Initiative. PMID: 20451872; PMCID: PMC2867843.
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    47. MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population. Alzheimer Dis Assoc Disord. 2009 Oct-Dec; 23(4):333-6. Raman R, Thomas RG, Weiner MW, Jack CR, Ernstrom K, Aisen PS, Tariot PN, Quinn JF. PMID: 19571733; PMCID: PMC2804922.
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    48. Plasma urate and progression of mild cognitive impairment. Neurodegener Dis. 2009; 6(1-2):23-8. Irizarry MC, Raman R, Schwarzschild MA, Becerra LM, Thomas RG, Peterson RC, Ascherio A, Aisen PS. PMID: 19066433; PMCID: PMC2745303.
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    49. High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial. JAMA. 2008 Oct 15; 300(15):1774-83. Aisen PS, Schneider LS, Sano M, Diaz-Arrastia R, van Dyck CH, Weiner MF, Bottiglieri T, Jin S, Stokes KT, Thomas RG, Thal LJ, Alzheimer Disease Cooperative Study. PMID: 18854539; PMCID: PMC2684821.
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    50. Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study. Lancet Neurol. 2008 Sep; 7(9):787-95. Meyer BC, Raman R, Hemmen T, Obler R, Zivin JA, Rao R, Thomas RG, Lyden PD. PMID: 18676180; PMCID: PMC2744128.
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    51. Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study. Lancet. 2008 Jul 19; 372(9634):207-15. Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, Seely L, Hung D, dimebon investigators. PMID: 18640457.
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    52. A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimers Dement. 2008 May; 4(3):156-63. Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, Hyman B, Kuller L, Schenk D, Snyder S, Thomas RG, Tuszynski MH, Vellas B, Wurtman RJ, Snyder PJ, Frank RA, Albert M, Doody R, Ferris S, Kaye J, Koo E, Morrison-Bogorad M, Reisberg B, Salmon DP, Gilman S, Mohs R, Aisen PS, Breitner JC, Cummings JL, Kawas C, Phelps C, Poirier J, Sabbagh M, Touchon J, Khachaturian AS, Bain LJ. PMID: 18631960; PMCID: PMC2544623.
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    53. Ametropia, preschoolers' cognitive abilities, and effects of spectacle correction. Arch Ophthalmol. 2008 Feb; 126(2):252-8; quiz 161. Roch-Levecq AC, Brody BL, Thomas RG, Brown SI. PMID: 18268218.
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    54. Potential outcome measures and trial design issues for multiple system atrophy. Mov Disord. 2007 Dec; 22(16):2371-7. May S, Gilman S, Sowell BB, Thomas RG, Stern MB, Colcher A, Tanner CM, Huang N, Novak P, Reich SG, Jankovic J, Ondo WG, Low PA, Sandroni P, Lipp A, Marshall FJ, Wooten F, Shults CW, North American Multiple System Atrophy Study Group. PMID: 17914727.
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    55. ADCS Prevention Instrument Project: pharmacoeconomics: assessing health-related resource use among healthy elderly. Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S191-202. Sano M, Zhu CW, Whitehouse PJ, Edland S, Jin S, Ernstrom K, Thomas RG, Thal LJ, Ferris SH, Alzheimer Disease Cooperative Study Group. PMID: 17135812; PMCID: PMC3229195.
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    56. Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers. Clin Cancer Res. 2005 Aug 01; 11(15):5451-61. Krajewska M, Kim H, Kim C, Kang H, Welsh K, Matsuzawa S, Tsukamoto M, Thomas RG, Assa-Munt N, Piao Z, Suzuki K, Perucho M, Krajewski S, Reed JC. PMID: 16061861.
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    57. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005 Jun 09; 352(23):2379-88. Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ, Alzheimer's Disease Cooperative Study Group. PMID: 15829527.
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    58. Self-management of age-related macular degeneration at the 6-month follow-up: a randomized controlled trial. Arch Ophthalmol. 2005 Jan; 123(1):46-53. Brody BL, Roch-Levecq AC, Thomas RG, Kaplan RM, Brown SI. PMID: 15642811.
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    59. Reliability of monitoring the clinical dementia rating in multicenter clinical trials. Alzheimer Dis Assoc Disord. 2004 Oct-Dec; 18(4):219-22. Schafer KA, Tractenberg RE, Sano M, Mackell JA, Thomas RG, Gamst A, Thal LJ, Morris JC, Alzheimer's Disease Cooperative Study. PMID: 15592134; PMCID: PMC4367865.
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    60. A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease. J Int Neuropsychol Soc. 2004 Sep; 10(5):689-97. Hamilton JM, Salmon DP, Galasko D, Delis DC, Hansen LA, Masliah E, Thomas RG, Thal LJ. PMID: 15327716.
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    61. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol. 2004 Jan; 61(1):59-66. Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 14732621.
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    62. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA. 2003 Jun 04; 289(21):2819-26. Aisen PS, Schafer KA, Grundman M, Pfeiffer E, Sano M, Davis KL, Farlow MR, Jin S, Thomas RG, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 12783912.
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    63. Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled study. Am J Psychiatry. 2003 Feb; 160(2):371-3. Raskind MA, Peskind ER, Kanter ED, Petrie EC, Radant A, Thompson CE, Dobie DJ, Hoff D, Rein RJ, Straits-Tröster K, Thomas RG, McFall MM. PMID: 12562588.
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    64. Estrogen levels do not correlate with improvement in cognition. Arch Neurol. 2003 Feb; 60(2):209-12. Thal LJ, Thomas RG, Mulnard R, Sano M, Grundman M, Schneider L. PMID: 12580705.
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    65. Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment. J Mol Neurosci. 2003; 20(3):241-8. Grundman M, Jack CR, Petersen RC, Kim HT, Taylor C, Datvian M, Weiner MF, DeCarli C, DeKosky ST, van Dyck C, Darvesh S, Yaffe K, Kaye J, Ferris SH, Thomas RG, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 14501003.
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    66. A randomized trial of the effect of a plant-based dietary pattern on additional breast cancer events and survival: the Women's Healthy Eating and Living (WHEL) Study. Control Clin Trials. 2002 Dec; 23(6):728-56. Pierce JP, Faerber S, Wright FA, Rock CL, Newman V, Flatt SW, Kealey S, Jones VE, Caan BJ, Gold EB, Haan M, Hollenbach KA, Jones L, Marshall JR, Ritenbaugh C, Stefanick ML, Thomson C, Wasserman L, Natarajan L, Thomas RG, Gilpin EA, Women's Healthy Eating and Living (WHEL) study group. PMID: 12505249.
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    67. Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype. J Int Neuropsychol Soc. 2002 Nov; 8(7):943-55. Lange KL, Bondi MW, Salmon DP, Galasko D, Delis DC, Thomas RG, Thal LJ. PMID: 12405546; PMCID: PMC1621042.
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    68. Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):23-7. Grundman M, Sencakova D, Jack CR, Petersen RC, Kim HT, Schultz A, Weiner MF, DeCarli C, DeKosky ST, van Dyck C, Thomas RG, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 12212787.
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    69. A phase I study of AIT-082 in healthy elderly volunteers. J Mol Neurosci. 2002 Jun; 18(3):283-93. Grundman M, Farlow M, Peavy G, Kim HT, Capparelli E, Schultz AN, Salmon DP, Ferris SH, Mobs R, Thomas RG, Schafer K, Campbell K, Hake AM, Schoos B, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 12059047.
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    70. Assessing Alzheimer's disease patients with the Cohen-Mansfield Agitation Inventory: scoring and clinical implications. J Psychiatr Res. 2002 Jan-Feb; 36(1):19-25. Weiner MF, Tractenberg RE, Jin S, Gamst A, Thomas RG, Koss E, Thal LJ. PMID: 11755457.
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    71. Investigating emergent symptomatology as an outcome measure in a behavioral study of Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2002; 14(3):303-10. Tractenberg RE, Gamst A, Thomas RG, Patterson M, Schneider LS, Thal LJ. PMID: 12154155; PMCID: PMC4371727.
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