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Human fetal tissue is critical for biomedical research. Stem Cell Reports. 2023 12 12; 18(12):2300-2312.
Brumbaugh J, Aguado BA, Lysaght T, Goldstein LSB. PMID: 37977142; PMCID: PMC10724055.
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PubMed Mentions: Fields:
Translation:
Humans
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Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease. Mol Brain. 2023 Nov 03; 16(1):75.
Valdes P, Henry KW, Fitzgerald MQ, Muralidharan K, Caldwell AB, Ramachandran S, Goldstein LSB, Mobley WC, Galasko DR, Subramaniam S. PMID: 37924159; PMCID: PMC10623777.
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Translation:
HumansCells
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Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons and Glia for the Elucidation of Pathogenic Mechanisms in Alzheimer's Disease. Methods Mol Biol. 2023; 2561:105-133.
Young JE, Goldstein LSB. PMID: 36399267.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Brain organoids, consciousness, ethics and moral status. Semin Cell Dev Biol. 2023 07 30; 144:97-102.
Jeziorski J, Brandt R, Evans JH, Campana W, Kalichman M, Thompson E, Goldstein L, Koch C, Muotri AR. PMID: 35339359.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons. J Neurosci. 2021 12 08; 41(49):10034-10053.
Chaves RS, Tran M, Holder AR, Balcer AM, Dickey AM, Roberts EA, Bober BG, Gutierrez E, Head BP, Groisman A, Goldstein LSB, Almenar-Queralt A, Shah SB. PMID: 34663629; PMCID: PMC8660048.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Evidence generation and reproducibility in cell and gene therapy research: A call to action. Mol Ther Methods Clin Dev. 2021 Sep 10; 22:11-14.
Abou-El-Enein M, Angelis A, Appelbaum FR, Andrews NC, Bates SE, Bierman AS, Brenner MK, Cavazzana M, Caligiuri MA, Clevers H, Cooke E, Daley GQ, Dzau VJ, Ellis LM, Fineberg HV, Goldstein LSB, Gottschalk S, Hamburg MA, Ingber DE, Kohn DB, Krainer AR, Maus MV, Marks P, Mummery CL, Pettigrew RI, Rutter JL, Teichmann SA, Terzic A, Urnov FD, Williams DA, Wolchok JD, Lawler M, Turtle CJ, Bauer G, Ioannidis JPA. PMID: 34377737; PMCID: PMC8322039.
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PubMed Mentions:
6
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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. 2021 09 02; 28(9):1533-1548.e6.
Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. PMID: 33910058; PMCID: PMC8423435.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Stem cells on the ballot. Science. 2021 01 15; 371(6526):215.
Goldstein LSB, Klein RN. PMID: 33446531.
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Translation:
HumansAnimalsCells
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Balancing Scientific Advice with Political Realities during the Campaign to Pass California's Ballot Proposition 14. Cell Stem Cell. 2021 01 07; 28(1):12-16.
Goldstein LSB. PMID: 33417866.
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PubMed Mentions: Fields:
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Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization. Mol Biol Cell. 2021 02 01; 32(3):247-259.
Langness VF, van der Kant R, Das U, Wang L, Chaves RDS, Goldstein LSB. PMID: 33296223; PMCID: PMC8098827.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention? Prog Mol Biol Transl Sci. 2021; 177:109-122.
Goldstein LSB, Das U. PMID: 33453937.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Amyloid-β-independent regulators of tau pathology in Alzheimer disease. Nat Rev Neurosci. 2020 01; 21(1):21-35.
van der Kant R, Goldstein LSB, Ossenkoppele R. PMID: 31780819.
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PubMed Mentions:
202 Fields:
Translation:
HumansAnimalsCells
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Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells. Nat Genet. 2019 12; 51(12):1691-1701.
Almenar-Queralt A, Merkurjev D, Kim HS, Navarro M, Ma Q, Chaves RS, Allegue C, Driscoll SP, Chen AG, Kohlnhofer B, Fong LK, Woodruff G, Mackintosh C, Bohaciakova D, Hruska-Plochan M, Tadokoro T, Young JE, El Hajj N, Dittrich M, Marsala M, Goldstein LSB, Garcia-Bassets I. PMID: 31740836; PMCID: PMC7061033.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons. Cell Stem Cell. 2019 03 07; 24(3):363-375.e9.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB. PMID: 30686764; PMCID: PMC6414424.
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PubMed Mentions:
139 Fields:
Translation:
AnimalsCells
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Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes. J Biol Chem. 2018 07 20; 293(29):11341-11357.
Fong LK, Yang MM, Dos Santos Chaves R, Reyna SM, Langness VF, Woodruff G, Roberts EA, Young JE, Goldstein LSB. PMID: 29858247; PMCID: PMC6065173.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein. Stem Cell Reports. 2018 03 13; 10(3):1046-1058.
Young JE, Fong LK, Frankowski H, Petsko GA, Small SA, Goldstein LSB. PMID: 29503090; PMCID: PMC5919412.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Stem Cell Reports. 2017 04 11; 8(4):1086-1100.
Panopoulos AD, D'Antonio M, Benaglio P, Williams R, Hashem SI, Schuldt BM, DeBoever C, Arias AD, Garcia M, Nelson BC, Harismendy O, Jakubosky DA, Donovan MKR, Greenwald WW, Farnam K, Cook M, Borja V, Miller CA, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Aguirre A, McGarry TJ, Matsui H, Li H, Reyna J, Rao F, O'Connor DT, Yeo GW, Evans SM, Chi NC, Jepsen K, Nariai N, Müller FJ, Goldstein LSB, Izpisua Belmonte JC, Adler E, Loring JF, Berggren WT, D'Antonio-Chronowska A, Smith EN, Frazer KA. PMID: 28410642; PMCID: PMC5390244.
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PubMed Mentions:
79 Fields:
Translation:
HumansCells
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High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 04 11; 8(4):1101-1111.
D'Antonio M, Woodruff G, Nathanson JL, D'Antonio-Chronowska A, Arias A, Matsui H, Williams R, Herrera C, Reyna SM, Yeo GW, Goldstein LSB, Panopoulos AD, Frazer KA. PMID: 28410643; PMCID: PMC5390243.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations. Cell Rep. 2016 10 11; 17(3):759-773.
Woodruff G, Reyna SM, Dunlap M, Van Der Kant R, Callender JA, Young JE, Roberts EA, Goldstein LS. PMID: 27732852; PMCID: PMC5796664.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Mechanical Ventilation Antioxidant Trial. Am J Crit Care. 2015 Sep; 24(5):440-5.
Howe KP, Clochesy JM, Goldstein LS, Owen H. PMID: 26330437.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells. Cell Stem Cell. 2015 Apr 02; 16(4):373-85.
Young JE, Boulanger-Weill J, Williams DA, Woodruff G, Buen F, Revilla AC, Herrera C, Israel MA, Yuan SH, Edland SD, Goldstein LS. PMID: 25772071; PMCID: PMC4388804.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP. PLoS One. 2015; 10(2):e0118379.
Weissmiller AM, Natera-Naranjo O, Reyna SM, Pearn ML, Zhao X, Nguyen P, Cheng S, Goldstein LS, Tanzi RE, Wagner SL, Mobley WC, Wu C. PMID: 25710492; PMCID: PMC4339551.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Cellular functions of the amyloid precursor protein from development to dementia. Dev Cell. 2015 Feb 23; 32(4):502-15.
van der Kant R, Goldstein LS. PMID: 25710536.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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Probing the secrets of Alzheimer's disease using human-induced pluripotent stem cell technology. Neurotherapeutics. 2015 Jan; 12(1):121-5.
Goldstein LS, Reyna S, Woodruff G. PMID: 25534395; PMCID: PMC4322074.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers. JAMA Neurol. 2014 Dec; 71(12):1481-9.
Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH. PMID: 25285942; PMCID: PMC4374637.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. Mol Biol Cell. 2015 Jan 15; 26(2):205-17.
Niederst ED, Reyna SM, Goldstein LS. PMID: 25392299; PMCID: PMC4294669.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Characterizing the composition of molecular motors on moving axonal cargo using "cargo mapping" analysis. J Vis Exp. 2014 Oct 30; (92):e52029.
Neumann S, Campbell GE, Szpankowski L, Goldstein LS, Encalada SE. PMID: 25406537; PMCID: PMC4353387.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. Neuron. 2014 Aug 20; 83(4):789-96.
Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH. PMID: 25123310; PMCID: PMC4144679.
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PubMed Mentions:
172 Fields:
Translation:
HumansAnimalsCells
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UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014 Feb 26; 34(9):3320-39.
Almenar-Queralt A, Falzone TL, Shen Z, Lillo C, Killian RL, Arreola AS, Niederst ED, Ng KS, Kim SN, Briggs SP, Williams DS, Goldstein LS. PMID: 24573290; PMCID: PMC3935090.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. J Cell Sci. 2014 Apr 01; 127(Pt 7):1537-49.
Otero MG, Alloatti M, Cromberg LE, Almenar-Queralt A, Encalada SE, Pozo Devoto VM, Bruno L, Goldstein LS, Falzone TL. PMID: 24522182.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys. 2014; 43:141-69.
Encalada SE, Goldstein LS. PMID: 24702007.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep. 2013 Nov 27; 5(4):974-85.
Woodruff G, Young JE, Martinez FJ, Buen F, Gore A, Kinaga J, Li Z, Yuan SH, Zhang K, Goldstein LS. PMID: 24239350; PMCID: PMC3867011.
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PubMed Mentions:
100 Fields:
Translation:
HumansCells
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Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013 Dec 06; 288(49):35222-36.
Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS. PMID: 24145027; PMCID: PMC3853272.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One. 2013; 8(6):e68324.
Duncan JE, Lytle NK, Zuniga A, Goldstein LS. PMID: 23840848; PMCID: PMC3694009.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Hum Mol Genet. 2013 Oct 01; 22(19):3828-43.
Gunawardena S, Yang G, Goldstein LS. PMID: 23710041; PMCID: PMC3766177.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. EMBO J. 2013 May 29; 32(11):1489-95.
Bianco P, Barker R, Brüstle O, Cattaneo E, Clevers H, Daley GQ, De Luca M, Goldstein L, Lindvall O, Mummery C, Robey PG, Sattler de Sousa E Brito C, Smith A. PMID: 23644381; PMCID: PMC3671253.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Position statement on the provision and procurement of human eggs for stem cell research. Cell Stem Cell. 2013 Mar 07; 12(3):285-91.
Haimes E, Skene L, Ballantyne AJ, Caulfield T, Goldstein LS, Hyun I, Kimmelman J, Robert JS, Roxland BE, Scott CT, Solbakk JH, Sugarman J, Taylor PL, Testa G, ISSCR. PMID: 23472870.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver. Semin Liver Dis. 2012 Nov; 32(4):298-306.
Ordonez MP, Goldstein LS. PMID: 23397530.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic. 2013 Mar; 14(3):295-308.
Weaver C, Leidel C, Szpankowski L, Farley NM, Shubeita GT, Goldstein LS. PMID: 23279138.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell. 2013 Mar 07; 12(3):316-28.
Goff DJ, Court Recart A, Sadarangani A, Chun HJ, Barrett CL, Krajewska M, Leu H, Low-Marchelli J, Ma W, Shih AY, Wei J, Zhai D, Geron I, Pu M, Bao L, Chuang R, Balaian L, Gotlib J, Minden M, Martinelli G, Rusert J, Dao KH, Shazand K, Wentworth P, Smith KM, Jamieson CA, Morris SR, Messer K, Goldstein LS, Hudson TJ, Marra M, Frazer KA, Pellecchia M, Reed JC, Jamieson CH. PMID: 23333150; PMCID: PMC3968867.
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PubMed Mentions:
108 Fields:
Translation:
HumansCells
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ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):1041-6.
Jiang Q, Crews LA, Barrett CL, Chun HJ, Court AC, Isquith JM, Zipeto MA, Goff DJ, Minden M, Sadarangani A, Rusert JM, Dao KH, Morris SR, Goldstein LS, Marra MA, Frazer KA, Jamieson CH. PMID: 23275297; PMCID: PMC3549099.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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New frontiers in human cell biology and medicine: can pluripotent stem cells deliver? J Cell Biol. 2012 Nov 12; 199(4):577-81.
Goldstein LS. PMID: 23148231; PMCID: PMC3494862.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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US election: Know your representatives. Nature. 2012 Sep 27; 489(7417):494-5.
Goldstein L. PMID: 23018948.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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An October call to arms: we are research! Mol Biol Cell. 2012 Sep; 23(17):3279-80.
Goldstein LS. PMID: 22936697; PMCID: PMC3431937.
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PubMed Mentions:
1 Fields:
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Alzheimer's disease in a dish: promises and challenges of human stem cell models. Hum Mol Genet. 2012 Oct 15; 21(R1):R82-9.
Young JE, Goldstein LS. PMID: 22865875; PMCID: PMC3459645.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet. 2012 Nov 01; 21(21):4587-601.
Rodrigues EM, Weissmiller AM, Goldstein LS. PMID: 22843498; PMCID: PMC3471392.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8582-7.
Szpankowski L, Encalada SE, Goldstein LS. PMID: 22582169; PMCID: PMC3365224.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Axonal transport and neurodegenerative disease: can we see the elephant? Prog Neurobiol. 2012 Dec; 99(3):186-90.
Goldstein LS. PMID: 22484448; PMCID: PMC3867006.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet. 2012 Jun 15; 21(12):2651-62.
Ordonez MP, Roberts EA, Kidwell CU, Yuan SH, Plaisted WC, Goldstein LS. PMID: 22437840; PMCID: PMC3363339.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell. 2012 May; 23(9):1700-14.
Reis GF, Yang G, Szpankowski L, Weaver C, Shah SB, Robinson JT, Hays TS, Danuser G, Goldstein LS. PMID: 22398725; PMCID: PMC3338437.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 2012 Jan 25; 482(7384):216-20.
Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS. PMID: 22278060; PMCID: PMC3338985.
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PubMed Mentions:
611 Fields:
Translation:
HumansCells
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Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One. 2012; 7(1):e29755.
Killian RL, Flippin JD, Herrera CM, Almenar-Queralt A, Goldstein LS. PMID: 22272245; PMCID: PMC3260181.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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In the trenches: lessons for scientists from California's Proposition 71 campaign. Mol Biol Cell. 2011 Nov; 22(21):3943-4.
Goldstein LS. PMID: 22039069; PMCID: PMC3204056.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A. 2011 Nov; 17(21-22):2583-92.
DeQuach JA, Yuan SH, Goldstein LS, Christman KL. PMID: 21883047; PMCID: PMC3204197.
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PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
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A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell. 2011 Nov; 22(21):4038-46.
Henthorn KS, Roux MS, Herrera C, Goldstein LS. PMID: 21880894; PMCID: PMC3204066.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges. Genome Med. 2011 Jul 27; 3(7):49.
Israel MA, Goldstein LS. PMID: 21867573; PMCID: PMC3221547.
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PubMed Mentions:
11 Fields:
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Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011 Mar 03; 471(7336):63-7.
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. PMID: 21368825; PMCID: PMC3074107.
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PubMed Mentions:
589 Fields:
Translation:
HumansCells
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Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One. 2011 Mar 02; 6(3):e17540.
Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, Carson CT. PMID: 21407814; PMCID: PMC3047583.
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PubMed Mentions:
199 Fields:
Translation:
HumansAnimalsCells
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Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell. 2011 Feb 18; 144(4):551-65.
Encalada SE, Szpankowski L, Xia CH, Goldstein LS. PMID: 21335237; PMCID: PMC3576050.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):3005-10.
Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. PMID: 21278334; PMCID: PMC3041068.
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PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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Unconventional allies: interdisciplinary approaches to science policy and funding. Trends Cell Biol. 2010 Dec; 20(12):695-8.
Goldstein LS. PMID: 21106464.
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PubMed Mentions:
1 Fields:
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Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet. 2010 Nov 15; 19(22):4399-408.
Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. PMID: 20817925; PMCID: PMC2957317.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell. 2010 Jul 02; 7(1):43-9.
Taylor PL, Barker RA, Blume KG, Cattaneo E, Colman A, Deng H, Edgar H, Fox IJ, Gerstle C, Goldstein LS, High KA, Lyall A, Parkman R, Pitossi FJ, Prentice ED, Rooke HM, Sipp DA, Srivastava A, Stayn S, Steinberg GK, Wagers AJ, Weissman IL. PMID: 20621049.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev. 2010 Jun 01; 24(11):1106-18.
Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA, Goldstein LS, Abujarour R, Ding S, Guan KL. PMID: 20516196; PMCID: PMC2878649.
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PubMed Mentions:
401 Fields:
Translation:
HumansAnimalsCells
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Why scientific details are important when novel technologies encounter law, politics, and ethics. J Law Med Ethics. 2010; 38(2):204-11.
Goldstein L. PMID: 20579243.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 2009 Dec 11; 284(50):34628-39.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. PMID: 19801628; PMCID: PMC2787325.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis. 2009 Oct; 36(1):11-25.
Shah SB, Nolan R, Davis E, Stokin GB, Niesman I, Canto I, Glabe C, Goldstein LS. PMID: 19497367.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci. 2009 May 06; 29(18):5758-67.
Falzone TL, Stokin GB, Lillo C, Rodrigues EM, Westerman EL, Williams DS, Goldstein LS. PMID: 19420244; PMCID: PMC3849468.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci. 2008 Dec 10; 28(50):13662-72.
Her LS, Goldstein LS. PMID: 19074039; PMCID: PMC6671757.
View in:
PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet. 2008 Nov 15; 17(22):3474-86.
Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. PMID: 18694898; PMCID: PMC2722897.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7594-9.
Yamanaka K, Boillee S, Roberts EA, Garcia ML, McAlonis-Downes M, Mikse OR, Cleveland DW, Goldstein LS. PMID: 18492803; PMCID: PMC2396671.
View in:
PubMed Mentions:
139 Fields:
Translation:
AnimalsCells
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Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell. 2007 Jun; 18(6):2081-9.
Haghnia M, Cavalli V, Shah SB, Schimmelpfeng K, Brusch R, Yang G, Herrera C, Pilling A, Goldstein LS. PMID: 17360970; PMCID: PMC1877108.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Ethics. The ISSCR guidelines for human embryonic stem cell research. Science. 2007 Feb 02; 315(5812):603-4.
Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N, Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO, Weissman IL, Wilmut I, Yu J, Zoloth L. PMID: 17272706.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci. 2006 Nov; 47(11):5039-46.
Jimeno D, Feiner L, Lillo C, Teofilo K, Goldstein LS, Pierce EA, Williams DS. PMID: 17065525; PMCID: PMC1904505.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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The genetics of axonal transport and axonal transport disorders. PLoS Genet. 2006 Sep 29; 2(9):e124.
Duncan JE, Goldstein LS. PMID: 17009871; PMCID: PMC1584265.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimals
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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 2006 Jul 06; 51(1):29-42.
Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC. PMID: 16815330.
View in:
PubMed Mentions:
270 Fields:
Translation:
HumansAnimalsCells
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Linking molecular motors to Alzheimer's disease. J Physiol Paris. 2006 Mar-May; 99(2-3):193-200.
Stokin GB, Goldstein LS. PMID: 16459060.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Axonal transport and Alzheimer's disease. Annu Rev Biochem. 2006; 75:607-27.
Stokin GB, Goldstein LS. PMID: 16756504.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res. 2006 Feb; 82(2):351-3.
Jimeno D, Lillo C, Roberts EA, Goldstein LS, Williams DS. PMID: 16337628.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Sunday Driver links axonal transport to damage signaling. J Cell Biol. 2005 Feb 28; 168(5):775-87.
Cavalli V, Kujala P, Klumperman J, Goldstein LS. PMID: 15738268; PMCID: PMC2171809.
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PubMed Mentions:
145 Fields:
Translation:
AnimalsCells
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Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science. 2005 Feb 25; 307(5713):1282-8.
Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. PMID: 15731448.
View in:
PubMed Mentions:
504 Fields:
Translation:
HumansAnimalsCells
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Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol. 2005 Jan; 62(1):46-51.
Gunawardena S, Goldstein LS. PMID: 15642849.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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A standardized kinesin nomenclature. J Cell Biol. 2004 Oct 11; 167(1):19-22.
Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L. PMID: 15479732; PMCID: PMC2041940.
View in:
PubMed Mentions:
310 Fields:
Translation:
HumansAnimals
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Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction. Curr Opin Cell Biol. 2004 Aug; 16(4):443-50.
Guzik BW, Goldstein LS. PMID: 15261678.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J Neurobiol. 2004 Feb 05; 58(2):258-71.
Gunawardena S, Goldstein LS. PMID: 14704957.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Do disorders of movement cause movement disorders and dementia? Neuron. 2003 Oct 09; 40(2):415-25.
Goldstein LS. PMID: 14556718.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 03; 302(5642):113-7.
Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. PMID: 14526083.
View in:
PubMed Mentions:
406 Fields:
Translation:
HumansAnimalsCells
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Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 2003 Sep 25; 40(1):25-40.
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. PMID: 14527431.
View in:
PubMed Mentions:
254 Fields:
Translation:
HumansAnimals
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Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol. 2003 Apr 14; 161(1):55-66.
Xia CH, Roberts EA, Her LS, Liu X, Williams DS, Cleveland DW, Goldstein LS. PMID: 12682084; PMCID: PMC2172877.
View in:
PubMed Mentions:
138 Fields:
Translation:
AnimalsCells
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Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5286-91.
Lin F, Hiesberger T, Cordes K, Sinclair AM, Goldstein LS, Somlo S, Igarashi P. PMID: 12672950; PMCID: PMC154337.
View in:
PubMed Mentions:
279 Fields:
Translation:
AnimalsCells
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JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell. 2003 Apr; 4(4):521-33.
Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M. PMID: 12689591.
View in:
PubMed Mentions:
162 Fields:
Translation:
AnimalsCells
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Loss of heterozygosity analysis of mouse pulmonary adenomas induced by coal tar. Environ Mol Mutagen. 2003; 41(4):300-8.
Benavides F, Conti CJ, LaCava M, Flores M, Glasscock E, Sternik G, Gimenez-Conti IB, Johnston DA, Dunsford HA, Goldstein LS, Rodriguez LV. PMID: 12717785.
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PubMed Mentions: Fields:
Translation:
Animals
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A genetic screen for suppressors and enhancers of the Drosophila cdk1-cyclin B identifies maternal factors that regulate microtubule and microfilament stability. Genetics. 2002 Nov; 162(3):1179-95.
Ji JY, Haghnia M, Trusty C, Goldstein LS, Schubiger G. PMID: 12454065; PMCID: PMC1462342.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Principles of cargo attachment to cytoplasmic motor proteins. Curr Opin Cell Biol. 2002 Feb; 14(1):63-8.
Kamal A, Goldstein LS. PMID: 11792546.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature. 2001 Dec 06; 414(6864):643-8.
Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS. PMID: 11740561.
View in:
PubMed Mentions:
205 Fields:
Translation:
AnimalsCells
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Molecular motors: from one motor many tails to one motor many tales. Trends Cell Biol. 2001 Dec; 11(12):477-82.
Goldstein LS. PMID: 11719052.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron. 2001 Nov 08; 32(3):389-401.
Gunawardena S, Goldstein LS. PMID: 11709151.
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PubMed Mentions:
180 Fields:
Translation:
HumansAnimalsCells
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Polarized fluorescence microscopy of individual and many kinesin motors bound to axonemal microtubules. Biophys J. 2001 Nov; 81(5):2851-63.
Peterman EJ, Sosa H, Goldstein LS, Moerner WE. PMID: 11606296; PMCID: PMC1301750.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Linkers, packages and pathways: new concepts in axonal transport. Curr Opin Neurobiol. 2001 Oct; 11(5):550-7.
Almenar-Queralt A, Goldstein LS. PMID: 11595487.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Functional analysis of mouse kinesin motor Kif3C. Mol Cell Biol. 2001 Aug; 21(16):5306-11.
Yang Z, Roberts EA, Goldstein LS. PMID: 11463814; PMCID: PMC87254.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
-
Kinesin molecular motors: transport pathways, receptors, and human disease. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):6999-7003.
Goldstein LS. PMID: 11416178; PMCID: PMC34613.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy. Nat Struct Biol. 2001 Jun; 8(6):540-4.
Sosa H, Peterman EJ, Moerner WE, Goldstein LS. PMID: 11373624.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Functional analysis of mouse C-terminal kinesin motor KifC2. Mol Cell Biol. 2001 Apr; 21(7):2463-6.
Yang Z, Roberts EA, Goldstein LS. PMID: 11259594; PMCID: PMC86878.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
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Transduction. When worlds collide--trafficking in JNK. Science. 2001 Mar 16; 291(5511):2102-3.
Goldstein LS. PMID: 11256408.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Mol Cell Biol. 2001 Feb; 21(3):765-70.
Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. PMID: 11154264; PMCID: PMC86668.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Cytoskeleton. Curr Opin Cell Biol. 2001 Feb; 13(1):17-8.
Goldstein LS, Theriot JA. PMID: 11163128.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 2000 Nov 10; 103(4):583-94.
Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS. PMID: 11106729.
View in:
PubMed Mentions:
130 Fields:
Translation:
AnimalsCells
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Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron. 2000 Nov; 28(2):449-59.
Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. PMID: 11144355.
View in:
PubMed Mentions:
187 Fields:
Translation:
AnimalsCells
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Connecting vesicle transport to the cytoskeleton. Curr Opin Cell Biol. 2000 Aug; 12(4):503-8.
Kamal A, Goldstein LS. PMID: 10873823.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Flying through the drosophila cytoskeletal genome. J Cell Biol. 2000 Jul 24; 150(2):F63-8.
Goldstein LS, Gunawardena S. PMID: 10908588; PMCID: PMC2180230.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors. Cell. 2000 Jul 21; 102(2):175-87.
Marszalek JR, Liu X, Roberts EA, Chui D, Marth JD, Williams DS, Goldstein LS. PMID: 10943838.
View in:
PubMed Mentions:
195 Fields:
Translation:
HumansAnimalsCells
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CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. J Cell Biol. 2000 Jul 10; 150(1):1-11.
Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. PMID: 10893249; PMCID: PMC2185570.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Does motor protein intelligence contribute to neuronal polarity? Neuron. 2000 May; 26(2):281-2.
Shah JV, Goldstein LS. PMID: 10839344.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Drosophila beta spectrin functions independently of alpha spectrin to polarize the Na,K ATPase in epithelial cells. J Cell Biol. 2000 May 01; 149(3):647-56.
Dubreuil RR, Wang P, Dahl S, Lee J, Goldstein LS. PMID: 10791978; PMCID: PMC2174857.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Comparative genomics of the eukaryotes. Science. 2000 Mar 24; 287(5461):2204-15.
Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W, Cherry JM, Henikoff S, Skupski MP, Misra S, Ashburner M, Birney E, Boguski MS, Brody T, Brokstein P, Celniker SE, Chervitz SA, Coates D, Cravchik A, Gabrielian A, Galle RF, Gelbart WM, George RA, Goldstein LS, Gong F, Guan P, Harris NL, Hay BA, Hoskins RA, Li J, Li Z, Hynes RO, Jones SJ, Kuehl PM, Lemaitre B, Littleton JT, Morrison DK, Mungall C, O'Farrell PH, Pickeral OK, Shue C, Vosshall LB, Zhang J, Zhao Q, Zheng XH, Lewis S. PMID: 10731134; PMCID: PMC2754258.
View in:
PubMed Mentions:
492 Fields:
Translation:
HumansAnimalsCells
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Understanding the functions of kinesin-II. Biochim Biophys Acta. 2000 Mar 17; 1496(1):142-50.
Marszalek JR, Goldstein LS. PMID: 10722883.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu Rev Neurosci. 2000; 23:39-71.
Goldstein LS, Yang Z. PMID: 10845058.
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PubMed Mentions:
175 Fields:
Translation:
HumansAnimalsCells
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Cloning and expression of kinesins from the thermophilic fungus Thermomyces lanuginosus. Protein Sci. 1999 Dec; 8(12):2705-10.
Sakowicz R, Farlow S, Goldstein LS. PMID: 10631986; PMCID: PMC2144245.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. J Cell Biol. 1999 Nov 01; 147(3):507-18.
Ray K, Perez SE, Yang Z, Xu J, Ritchings BW, Steller H, Goldstein LS. PMID: 10545496; PMCID: PMC2151187.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. J Cell Biol. 1999 Sep 20; 146(6):1277-88.
Rahman A, Kamal A, Roberts EA, Goldstein LS. PMID: 10491391; PMCID: PMC2156125.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Adociasulfates 1-6, Inhibitors of Kinesin Motor Proteins from the Sponge Haliclona (aka Adocia) sp. J Org Chem. 1999 Jul 23; 64(15):5565-5570.
Blackburn CL, Hopmann C, Sakowicz R, Berdelis MS, Goldstein LS, Faulkner DJ. PMID: 11674622.
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PubMed Mentions:
7 Fields:
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Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. J Cell Biol. 1999 Jul 12; 146(1):165-80.
Bowman AB, Patel-King RS, Benashski SE, McCaffery JM, Goldstein LS, King SM. PMID: 10402468; PMCID: PMC2199740.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol. 1999 May 03; 145(3):469-79.
Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS. PMID: 10225949; PMCID: PMC2185086.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9):5043-8.
Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS. PMID: 10220415; PMCID: PMC21813.
View in:
PubMed Mentions:
217 Fields:
Translation:
AnimalsCells
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The road less traveled: emerging principles of kinesin motor utilization. Annu Rev Cell Dev Biol. 1999; 15:141-83.
Goldstein LS, Philp AV. PMID: 10611960.
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PubMed Mentions:
88 Fields:
Translation:
HumansAnimals
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Chromosomal localization reveals three kinesin heavy chain genes in mouse. Genomics. 1998 Sep 01; 52(2):209-13.
Xia Ch, Rahman A, Yang Z, Goldstein LS. PMID: 9782088.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. J Biol Chem. 1998 Jun 19; 273(25):15395-403.
Rahman A, Friedman DS, Goldstein LS. PMID: 9624122.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Kinesin light chains are essential for axonal transport in Drosophila. J Cell Biol. 1998 Apr 20; 141(2):443-54.
Gindhart JG, Desai CJ, Beushausen S, Zinn K, Goldstein LS. PMID: 9548722; PMCID: PMC2148443.
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PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
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A marine natural product inhibitor of kinesin motors. Science. 1998 Apr 10; 280(5361):292-5.
Sakowicz R, Berdelis MS, Ray K, Blackburn CL, Hopmann C, Faulkner DJ, Goldstein LS. PMID: 9535660.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Cruising along microtubule highways: how membranes move through the secretory pathway. J Cell Biol. 1998 Mar 23; 140(6):1277-80.
Bloom GS, Goldstein LS. PMID: 9508761; PMCID: PMC2132669.
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PubMed Mentions:
32 Fields:
Translation:
Cells
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Characterization of the KIF3C neural kinesin-like motor from mouse. Mol Biol Cell. 1998 Feb; 9(2):249-61.
Yang Z, Goldstein LS. PMID: 9450952; PMCID: PMC25248.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell. 1997 Oct 31; 91(3):357-66.
Wood KW, Sakowicz R, Goldstein LS, Cleveland DW. PMID: 9363944.
View in:
PubMed Mentions:
173 Fields:
Translation:
HumansAnimalsCells
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Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. Genomics. 1997 Oct 01; 45(1):123-31.
Yang Z, Hanlon DW, Marszalek JR, Goldstein LS. PMID: 9339368.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Probing the kinesin-microtubule interaction. J Biol Chem. 1997 Apr 04; 272(14):9481-8.
Tucker C, Goldstein LS. PMID: 9083088.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. J Cell Biol. 1997 Mar 10; 136(5):1081-90.
Pereira AJ, Dalby B, Stewart RJ, Doxsey SJ, Goldstein LS. PMID: 9060472; PMCID: PMC2132485.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron. 1997 Mar; 18(3):439-51.
Hanlon DW, Yang Z, Goldstein LS. PMID: 9115737.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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alpha-Spectrin is required for ovarian follicle monolayer integrity in Drosophila melanogaster. Development. 1997 Jan; 124(2):353-62.
Lee JK, Brandin E, Branton D, Goldstein LS. PMID: 9053311.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Armadillo repeats in the SpKAP115 subunit of kinesin-II. Trends Cell Biol. 1996 Nov; 6(11):415-6.
Gindhart JG, Goldstein LS. PMID: 15157510.
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PubMed Mentions:
9 Fields:
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Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein. J Cell Biol. 1996 Jul; 134(2):455-64.
Matthies HJ, McDonald HB, Goldstein LS, Theurkauf WE. PMID: 8707829; PMCID: PMC2120873.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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The muscle in kinesin. Nat Struct Biol. 1996 May; 3(5):404-7.
Sakowicz R, Goldstein LS. PMID: 8612068.
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PubMed Mentions: Fields:
Translation:
Cells
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Going mobile: microtubule motors and chromosome segregation. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):1735-42.
Barton NR, Goldstein LS. PMID: 8700828; PMCID: PMC39850.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell. 1996 Feb 23; 84(4):599-609.
Desai CJ, Gindhart JG, Goldstein LS, Zinn K. PMID: 8598046.
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PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Tetratrico peptide repeats are present in the kinesin light chain. Trends Biochem Sci. 1996 Feb; 21(2):52-3.
Gindhart JG, Goldstein LS. PMID: 8851660.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Motor activity and mitotic spindle localization of the Drosophila kinesin-like protein KLP61F. Mol Biol Cell. 1995 Nov; 6(11):1563-74.
Barton NR, Pereira AJ, Goldstein LS. PMID: 8589456; PMCID: PMC301311.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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DNA binding and meiotic chromosomal localization of the Drosophila nod kinesin-like protein. Cell. 1995 Apr 07; 81(1):129-38.
Afshar K, Barton NR, Hawley RS, Goldstein LS. PMID: 7720068.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Structural features involved in force generation in the kinesin superfamily. Biophys J. 1995 Apr; 68(4 Suppl):260S-265S; discussion 265S-266S.
Goldstein LS. PMID: 7787087; PMCID: PMC1281940.
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An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics. 1995 Feb; 139(2):757-66.
Dalby B, Pereira AJ, Goldstein LS. PMID: 7713430; PMCID: PMC1206379.
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18 Fields:
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AnimalsCells
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Drosophila development requires spectrin network formation. J Cell Biol. 1995 Jan; 128(1-2):71-9.
Deng H, Lee JK, Goldstein LS, Branton D. PMID: 7822424; PMCID: PMC2120337.
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15 Fields:
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HumansAnimalsCells
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Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport. J Cell Biol. 1994 Nov; 127(4):1041-8.
Pesavento PA, Stewart RJ, Goldstein LS. PMID: 7525600; PMCID: PMC2200055.
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27 Fields:
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AnimalsCells
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Sources of information about the fly: where to look it up. Methods Cell Biol. 1994; 44:3-12.
Goldstein LS. PMID: 7707959.
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Animals
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Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster. J Cell Biol. 1993 Dec; 123(6 Pt 2):1797-809.
Lee JK, Coyne RS, Dubreuil RR, Goldstein LS, Branton D. PMID: 8276898; PMCID: PMC2290878.
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59 Fields:
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AnimalsCells
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The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J Cell Biol. 1993 Nov; 123(3):665-79.
Heck MM, Pereira A, Pesavento P, Yannoni Y, Spradling AC, Goldstein LS. PMID: 8227131; PMCID: PMC2200134.
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120 Fields:
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AnimalsCells
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The Drosophila kinesin light chain. Primary structure and interaction with kinesin heavy chain. J Biol Chem. 1993 Jun 25; 268(18):13657-66.
Gauger AK, Goldstein LS. PMID: 8514798.
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43 Fields:
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AnimalsCells
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Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5209-13.
Stewart RJ, Thaler JP, Goldstein LS. PMID: 8506368; PMCID: PMC46685.
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49 Fields:
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AnimalsCells
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With apologies to scheherazade: tails of 1001 kinesin motors. Annu Rev Genet. 1993; 27:319-51.
Goldstein LS. PMID: 8122906.
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58 Fields:
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HumansAnimalsCells
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Functional redundancy in mitotic force generation. J Cell Biol. 1993 Jan; 120(1):1-3.
Goldstein LS. PMID: 8416980; PMCID: PMC2119490.
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18 Fields:
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AnimalsCells
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Cell biology. New cytoskeletal liaisons. Nature. 1992 Sep 17; 359(6392):193-4.
Goldstein LS, Vale RD. PMID: 1388245.
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PubMed Mentions:
6 Fields:
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AnimalsCells
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Evidence that the stalk of Drosophila kinesin heavy chain is an alpha-helical coiled coil. J Cell Biol. 1992 Feb; 116(4):957-65.
de Cuevas M, Tao T, Goldstein LS. PMID: 1734025; PMCID: PMC2289341.
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36 Fields:
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AnimalsCells
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Genetic analysis of a Drosophila microtubule-associated protein. J Cell Biol. 1992 Jan; 116(2):377-83.
Pereira A, Doshen J, Tanaka E, Goldstein LS. PMID: 1309812; PMCID: PMC2289276.
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PubMed Mentions:
15 Fields:
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AnimalsCells
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The kinesin superfamily: tails of functional redundancy. Trends Cell Biol. 1991 Oct; 1(4):93-8.
Goldstein LS. PMID: 14731795.
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40 Fields:
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Identification and partial characterization of six members of the kinesin superfamily in Drosophila. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8470-4.
Stewart RJ, Pesavento PA, Woerpel DN, Goldstein LS. PMID: 1924306; PMCID: PMC52530.
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43 Fields:
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AnimalsCells
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Motor proteins. A brave new world for dynein. Nature. 1991 Aug 15; 352(6336):569-70.
Goldstein LS, Vale RD. PMID: 1830924.
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2 Fields:
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AnimalsCells
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Structure, calmodulin-binding, and calcium-binding properties of recombinant alpha spectrin polypeptides. J Biol Chem. 1991 Apr 15; 266(11):7189-93.
Dubreuil RR, Brandin E, Reisberg JH, Goldstein LS, Branton D. PMID: 2016322.
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7 Fields:
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AnimalsCells
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Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis. Cell. 1991 Mar 22; 64(6):1093-102.
Saxton WM, Hicks J, Goldstein LS, Raff EC. PMID: 1825937.
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80 Fields:
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Animals
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The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor. Cell. 1990 Dec 21; 63(6):1159-65.
McDonald HB, Stewart RJ, Goldstein LS. PMID: 2261638.
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126 Fields:
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AnimalsCells
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Analysis of the primary sequence and microtubule-binding region of the Drosophila 205K MAP. J Cell Biol. 1990 Dec; 111(6 Pt 1):2563-72.
Irminger-Finger I, Laymon RA, Goldstein LS. PMID: 1703540; PMCID: PMC2116399.
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14 Fields:
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AnimalsCells
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Bead movement by single kinesin molecules studied with optical tweezers. Nature. 1990 Nov 22; 348(6299):348-52.
Block SM, Goldstein LS, Schnapp BJ. PMID: 2174512.
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270 Fields:
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Cells
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A kinesin-like protein required for distributive chromosome segregation in Drosophila. Cell. 1990 Sep 21; 62(6):1053-62.
Zhang P, Knowles BA, Goldstein LS, Hawley RS. PMID: 2144792.
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87 Fields:
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AnimalsCells
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Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science. 1990 Jul 06; 249(4964):42-7.
Yang JT, Saxton WM, Stewart RJ, Raff EC, Goldstein LS. PMID: 2142332.
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67 Fields:
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AnimalsCells
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Identification and characterization of a gene encoding a kinesin-like protein in Drosophila. Cell. 1990 Jun 15; 61(6):991-1000.
McDonald HB, Goldstein LS. PMID: 2140958.
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63 Fields:
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AnimalsCells
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One motor, many tails: an expanding repertoire of force-generating enzymes. Cell. 1990 Mar 23; 60(6):883-5.
Vale RD, Goldstein LS. PMID: 2138513.
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39 Fields:
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Animals
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The conditional inhibition of gene expression in cultured Drosophila cells by antisense RNA. Nucleic Acids Res. 1989 Dec 11; 17(23):9761-82.
Bunch TA, Goldstein LS. PMID: 2481266; PMCID: PMC335212.
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6 Fields:
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AnimalsCells
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The complete sequence of Drosophila alpha-spectrin: conservation of structural domains between alpha-spectrins and alpha-actinin. J Cell Biol. 1989 Nov; 109(5):2197-205.
Dubreuil RR, Byers TJ, Sillman AL, Bar-Zvi D, Goldstein LS, Branton D. PMID: 2808524; PMCID: PMC2115856.
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PubMed Mentions:
25 Fields:
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AnimalsCells
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Sequence similarity of the amino-terminal domain of Drosophila beta spectrin to alpha actinin and dystrophin. J Cell Biol. 1989 Oct; 109(4 Pt 1):1633-41.
Byers TJ, Husain-Chishti A, Dubreuil RR, Branton D, Goldstein LS. PMID: 2677025; PMCID: PMC2115807.
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53 Fields:
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AnimalsCells
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Identification of globular mechanochemical heads of kinesin. Nature. 1989 Mar 23; 338(6213):355-7.
Scholey JM, Heuser J, Yang JT, Goldstein LS. PMID: 2493586.
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65 Fields:
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AnimalsCells
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A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell. 1989 Mar 10; 56(5):879-89.
Yang JT, Laymon RA, Goldstein LS. PMID: 2522352.
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130 Fields:
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AnimalsCells
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Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. EMBO J. 1989 Mar; 8(3):913-22.
Kiehart DP, Lutz MS, Chan D, Ketchum AS, Laymon RA, Nguyen B, Goldstein LS. PMID: 2498088; PMCID: PMC400891.
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PubMed Mentions:
23 Fields:
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AnimalsCells
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Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin. Proc Natl Acad Sci U S A. 1988 Mar; 85(6):1864-8.
Yang JT, Saxton WM, Goldstein LS. PMID: 3126498; PMCID: PMC279881.
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26 Fields:
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AnimalsCells
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Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res. 1988 Feb 11; 16(3):1043-61.
Bunch TA, Grinblat Y, Goldstein LS. PMID: 3125519; PMCID: PMC334736.
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143 Fields:
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AnimalsCells
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Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. J Cell Biol. 1987 Nov; 105(5):2103-10.
Byers TJ, Dubreuil R, Branton D, Kiehart DP, Goldstein LS. PMID: 2824526; PMCID: PMC2114868.
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38 Fields:
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AnimalsCells
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Drosophilia spectrin. I. Characterization of the purified protein. J Cell Biol. 1987 Nov; 105(5):2095-102.
Dubreuil R, Byers TJ, Branton D, Goldstein LS, Kiehart DP. PMID: 3680372; PMCID: PMC2114846.
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48 Fields:
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AnimalsCells
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A microtubule-associated protein in Drosophila melanogaster: identification, characterization, and isolation of coding sequences. J Cell Biol. 1986 Jun; 102(6):2076-87.
Goldstein LS, Laymon RA, McIntosh JR. PMID: 3086324; PMCID: PMC2114242.
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29 Fields:
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AnimalsCells
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Kinetochore structure and its role in chromosome orientation during the first meiotic division in male D. melanogaster. Cell. 1981 Sep; 25(3):591-602.
Goldstein LS. PMID: 6793236.
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58 Fields:
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AnimalsCells
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Detecting mutations expressed during early development of cultured mammalian embryos. Genetics. 1979 May; 92(1 Pt 1 Suppl):s143-51.
Pedersen RA, Goldstein LS. PMID: 488698.
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Animals