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    Atul Malhotra

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9300 Campus Point Drive #7381
    CA La Jolla 92037
    Phone858-657-6159
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Training in the Next Generation in Respiratory Science
      NIH T32HL134632Feb 1, 2017 - Jan 31, 2022
      Role: Principal Investigator
      Assessment of Upper Airway Mechanics Using Newer Electromyographic Techniques
      NIH K24HL132105Jun 1, 2016 - Feb 28, 2021
      Role: Principal Investigator
      Obstructive Sleep Apnea Increases Cardiovascular Risk in Type 2 Diabetes
      NIH R01HL110350Dec 1, 2011 - Jun 30, 2017
      Role: Principal Investigator
      Assessment of Upper Airway Mechanics Using Newer EMG Techniques
      NIH K24HL093218Jul 1, 2009 - Jun 30, 2014
      Role: Principal Investigator
      Mechanisms Underlying the Aging Predisposition to Obstructive Sleep Apnea
      NIH R01HL090897Jul 1, 2009 - Jun 30, 2013
      Role: Principal Investigator
      Mechanisms of Arousal in Sleep Apnea
      NIH P01HL095491Apr 1, 2009 - May 31, 2020
      Role: Co-Investigator
      Is Neuromyopathy Important in Obstructive Sleep Apnea?
      NIH R01HL085188Jul 1, 2006 - Mar 31, 2019
      Role: Principal Investigator
      Aging Influence on the Development of Sleep Apnea
      NIH K23AG024837Sep 30, 2004 - Jun 30, 2009
      Role: Principal Investigator
      Sleep Apnea and Obesity: Cardiovascular Risk Assessment
      NIH R01HL073146Sep 1, 2003 - Feb 28, 2010
      Role: Principal Investigator
      General Clinical Research Center
      NIH M01RR001032Dec 1, 1977 - Mar 31, 2010
      Role: Co-Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Sands SA, Mebrate Y, Edwards BA, Nemati S, Manisty CH, Desai AS, Wellman A, Willson K, Francis DP, Butler JP, Malhotra A. Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure. Am J Respir Crit Care Med. 2017 Jan 15; 195(2):237-246. PMID: 27559818.
        View in: PubMed
      2. Subramani Y, Singh M, Wong J, Kushida CA, Malhotra A, Chung F. Understanding Phenotypes of Obstructive Sleep Apnea: Applications in Anesthesia, Surgery, and Perioperative Medicine. Anesth Analg. 2016 Nov 17. PMID: 27861433.
        View in: PubMed
      3. Feliciano A, Vaz F, Torres VM, Valentim-Coelho C, Silva R, Prosinecki V, Alexandre BM, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. Evening-morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters. Biochim Biophys Acta. 2016 Nov 15. PMID: 27864139.
        View in: PubMed
      4. Li Y, Owens RL, Sands S, Orr J, Moraes W, DeYoung P, Smales E, Jen R, Malhotra A. The Effect of Donepezil on Arousal Threshold and Apnea-Hypopnea Index. A Randomized, Double-Blind, Cross-Over Study. Ann Am Thorac Soc. 2016 Nov; 13(11):2012-2018. PMID: 27442715.
        View in: PubMed
      5. Edwards BA, Sands SA, Owens RL, Eckert DJ, Landry S, White DP, Malhotra A, Wellman A. The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility. Sleep. 2016 Nov 1; 39(11):1973-1983. PMID: 27634790.
        View in: PubMed
      6. Orr JE, Malhotra A, Sands SA. Pathogenesis of central and complex sleep apnoea. Respirology. 2016 Oct 31. PMID: 27797160.
        View in: PubMed
      7. Beitler JR, Malhotra A, Thompson BT. Ventilator-induced Lung Injury. Clin Chest Med. 2016 Dec; 37(4):633-646. PMID: 27842744.
        View in: PubMed
      8. Orr JE, Smales C, Alexander TH, Stepnowsky C, Pillar G, Malhotra A, Sarmiento KF. Treatment of OSA with CPAP is Associated with Improvement in PTSD Symptoms among Veterans. J Clin Sleep Med. 2016 Sep 29. PMID: 27707436.
        View in: PubMed
      9. Owens RL, Gold KA, Gozal D, Peppard PE, Jun JC, Lippman SM, Malhotra A. Sleep and Breathing … and Cancer? Cancer Prev Res (Phila). 2016 Nov; 9(11):821-827. PMID: 27604751.
        View in: PubMed
      10. Strollo PJ, Malhotra A. Stimulating therapy for obstructive sleep apnoea. Thorax. 2016 Oct; 71(10):879-80. PMID: 27488564.
        View in: PubMed
      11. Chung F, Memtsoudis SG, Ramachandran SK, Nagappa M, Opperer M, Cozowicz C, Patrawala S, Lam D, Kumar A, Joshi GP, Fleetham J, Ayas N, Collop N, Doufas AG, Eikermann M, Englesakis M, Gali B, Gay P, Hernandez AV, Kaw R, Kezirian EJ, Malhotra A, Mokhlesi B, Parthasarathy S, Stierer T, Wappler F, Hillman DR, Auckley D. Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea. Anesth Analg. 2016 Aug; 123(2):452-73. PMID: 27442772.
        View in: PubMed
      12. Tran S, Deacon N, Minokadeh A, Malhotra A, Davis DP, Villanueva S, Sell RE. Frequency and survival pattern of in-hospital cardiac arrests: The impacts of etiology and timing. Resuscitation. 2016 Oct; 107:13-8. PMID: 27456394.
        View in: PubMed
      13. Scholten EL, Beitler JR, Prisk GK, Malhotra A. Treatment of Acute Respiratory Distress Syndrome with Prone Positioning. Chest. 2016 Jul 8. PMID: 27400909.
        View in: PubMed
      14. Malhotra A, Liang NC. Introduction: American Thoracic Society International Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S528-9. PMID: 27606083; PMCID: PMC4990682.
      15. Akrami K, Sweeney DA, Malhotra A. Antibiotic stewardship in the intensive care unit: tools for de-escalation from the American Thoracic Society Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S533-5. PMID: 27606085; PMCID: PMC4990674.
      16. Jaiswal SJ, Malhotra A, Owens RL. Sleep and critical illness: bridging the two pillars at the ATS 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S536-8. PMID: 27606086; PMCID: PMC4990683.
      17. Malhotra A, Jordan A. The importance of arousal in obstructive sleep apnea-updates from the American Thoracic Society 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S542-4. PMID: 27606088; PMCID: PMC4990689.
      18. Deacon N, Malhotra A. Potential protective mechanism of arousal in obstructive sleep apnea. J Thorac Dis. 2016 Jul; 8(Suppl 7):S545-6. PMID: 27606089; PMCID: PMC4990681.
      19. Hepokoski M, Owens RL, Malhotra A, Beitler JR. Mechanical ventilation in acute respiratory distress syndrome at ATS 2016: the search for a patient-specific strategy. J Thorac Dis. 2016 Jul; 8(Suppl 7):S550-2. PMID: 27606091; PMCID: PMC4990680.
      20. Anderson RJ, Malhotra A, Kim NH. Pulmonary hypertension: evolution of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. J Thorac Dis. 2016 Jul; 8(Suppl 7):S562-5. PMID: 27606095; PMCID: PMC4990675.
      21. Fiallo L, Malhotra A, LaBuzetta JN. A primer of neurologic emergencies: summary from the American Thoracic Society Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S576-8. PMID: 27606099; PMCID: PMC4990677.
      22. Lam MT, Grandner MA, Malhotra A. Lungs can tell time-a highlight from 2016 ATS session on clock genes, inflammation, immunology, and sleep. J Thorac Dis. 2016 Jul; 8(Suppl 7):S579-81. PMID: 27606100; PMCID: PMC4990684.
      23. Zaremba S, Shin CH, Hutter MM, Malviya SA, Grabitz SD, MacDonald T, Diaz-Gil D, Ramachandran SK, Hess D, Malhotra A, Eikermann M. Continuous Positive Airway Pressure Mitigates Opioid-induced Worsening of Sleep-disordered Breathing Early after Bariatric Surgery. Anesthesiology. 2016 Jul; 125(1):92-104. PMID: 27171827.
        View in: PubMed
      24. Truong KK, Lam MT, Grandner MA, Sassoon CS, Malhotra A. Timing Matters: Circadian Rhythm in Sepsis, Obstructive Lung Disease, Obstructive Sleep Apnea, and Cancer. Ann Am Thorac Soc. 2016 Jul; 13(7):1144-54. PMID: 27104378.
        View in: PubMed
      25. Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. Intensive Care Med. 2016 Sep; 42(9):1427-36. PMID: 27342819.
        View in: PubMed
      26. Beitler JR, Owens RL, Malhotra A. Unmasking a Role for Noninvasive Ventilation in Early Acute Respiratory Distress Syndrome. JAMA. 2016 Jun 14; 315(22):2401-3. PMID: 27179463.
        View in: PubMed
      27. Jen R, Li Y, Owens RL, Malhotra A. Sleep in Chronic Obstructive Pulmonary Disease: Evidence Gaps and Challenges. Can Respir J. 2016; 2016:7947198. PMID: 27445564.
        View in: PubMed
      28. Chung F, Memtsoudis S, Krishna Ramachandran S, Nagappa M, Opperer M, Cozowicz C, Patrawala S, Lam D, Kumar A, Joshi GP, Fleetham J, Ayas N, Collop N, Doufas A, Eikermann M, Englesakis M, Gali B, Gay P, Hernandes A, Kaw R, Kezirian E, Malhotra A, Mokhlesi B, Parthasarathy S, Stierer T, Wappler F, Hillman DR, Auckley D. Society of Anesthesia and Sleep Medicine Guideline on Preoperative Screening and Assessment of Patients With Obstructive Sleep Apnea. Anesth Analg. 2016 Jun 01. PMID: 27258078.
        View in: PubMed
      29. Ha D, Mazzone PJ, Ries AL, Malhotra A, Fuster M. The Utility of Exercise Testing in Patients with Lung Cancer. J Thorac Oncol. 2016 Sep; 11(9):1397-410. PMID: 27156441.
        View in: PubMed
      30. Malhotra A. Looking Back at My American Thoracic Society Presidency. Attracting and Retaining the Next Generation. Am J Respir Crit Care Med. 2016 May 1; 193(9):946-8. PMID: 27128705.
        View in: PubMed
      31. Woodell TB, Hughes-Austin JM, Tran TV, Malhotra A, Abdelmalek JA, Rifkin DE. Associations between cystatin C-based eGFR, ambulatory blood pressure parameters, and in-clinic versus ambulatory blood pressure agreement in older community-living adults. Blood Press Monit. 2016 Apr; 21(2):87-94. PMID: 26683379; NIHMSID: NIHMS736528 [Available on 04/01/17].
        View in: PubMed
      32. Sands SA, Owens RL, Malhotra A. New Approaches to Diagnosing Sleep-Disordered Breathing. Sleep Med Clin. 2016 Jun; 11(2):143-52. PMID: 27236052.
        View in: PubMed
      33. Berngard SC, Beitler JR, Malhotra A. Personalizing mechanical ventilation for acute respiratory distress syndrome. J Thorac Dis. 2016 Mar; 8(3):E172-4. PMID: 27076966.
        View in: PubMed
      34. Sweeney DA, Akrami K, Malhotra A. Improved Outcomes in Critically Ill Patients With AIDS: How Does This Trend Continue? Crit Care Med. 2016 Feb; 44(2):446-7. PMID: 26771791.
        View in: PubMed
      35. Schorr F, Kayamori F, Hirata RP, Danzi-Soares NJ, Gebrim EM, Moriya HT, Malhotra A, Lorenzi-Filho G, Genta PR. Different Craniofacial Characteristics Predict Upper Airway Collapsibility in Japanese-Brazilian and White Men. Chest. 2016 Mar; 149(3):737-46. PMID: 26291487.
        View in: PubMed
      36. Beitler JR, Majumdar R, Hubmayr RD, Malhotra A, Thompson BT, Owens RL, Loring SH, Talmor D. Volume Delivered During Recruitment Maneuver Predicts Lung Stress in Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Jan; 44(1):91-9. PMID: 26474111.
        View in: PubMed
      37. Deacon NL, Jen R, Li Y, Malhotra A. Treatment of Obstructive Sleep Apnea. Prospects for Personalized Combined Modality Therapy. Ann Am Thorac Soc. 2016 Jan; 13(1):101-8. PMID: 26569377.
        View in: PubMed
      38. Orr JE, Auger WR, DeYoung PN, Kim NH, Malhotra A, Owens RL. Usefulness of Low Cardiac Index to Predict Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension. Am J Cardiol. 2016 Mar 15; 117(6):1001-5. PMID: 26805659.
        View in: PubMed
      39. Beitler JR, Guérin C, Ayzac L, Mancebo J, Bates DM, Malhotra A, Talmor D. PEEP titration during prone positioning for acute respiratory distress syndrome. Crit Care. 2015; 19:436. PMID: 26686509.
        View in: PubMed
      40. Shin W, Jen R, Li Y, Malhotra A. Tailored treatment strategies for obstructive sleep apnea. Respir Investig. 2016 Jan; 54(1):2-7. PMID: 26718138.
        View in: PubMed
      41. Phillips B, Gozal D, Malhotra A. What Is the Future of Sleep Medicine in the United States? Am J Respir Crit Care Med. 2015 Oct 15; 192(8):915-7. PMID: 26308722.
        View in: PubMed
      42. Kohli P, Pinto-Plata V, Divo M, Malhotra A, Harris RS, Lazaar A, Flynn A, Tal-Singer R, Panettieri RA, Celli B. Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. J Cardiopulm Rehabil Prev. 2015 Sep-Oct; 35(5):348-55. PMID: 26309192.
        View in: PubMed
      43. Stanchina M, Robinson K, Corrao W, Donat W, Sands S, Malhotra A. Clinical Use of Loop Gain Measures to Determine Continuous Positive Airway Pressure Efficacy in Patients with Complex Sleep Apnea. A Pilot Study. Ann Am Thorac Soc. 2015 Sep; 12(9):1351-7. PMID: 26214564.
        View in: PubMed
      44. Crotty Alexander L, Fuster M, Montgrain P, Malhotra A. The Need for More E-Cigarette Data: A Call to Action. Am J Respir Crit Care Med. 2015 Aug 1; 192(3):275-6. PMID: 26230232.
        View in: PubMed
      45. Soler X, Gaio E, Powell FL, Ramsdell JW, Loredo JS, Malhotra A, Ries AL. High Prevalence of Obstructive Sleep Apnea in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2015 Aug; 12(8):1219-25. PMID: 25871443.
        View in: PubMed
      46. Rice MB, Malhotra A. The air we breathe and lung disease. J Thorac Dis. 2015 Aug; 7(8):E245-7. PMID: 26380790.
        View in: PubMed
      47. Donovan LM, Boeder S, Malhotra A, Patel SR. New developments in the use of positive airway pressure for obstructive sleep apnea. J Thorac Dis. 2015 Aug; 7(8):1323-42. PMID: 26380760.
        View in: PubMed
      48. Crotty Alexander LE, Vyas A, Schraufnagel DE, Malhotra A. Electronic cigarettes: the new face of nicotine delivery and addiction. J Thorac Dis. 2015 Aug; 7(8):E248-51. PMID: 26380791.
        View in: PubMed
      49. Ayas NT, Patil SP, Stanchina M, Malhotra A. Treatment of Central Sleep Apnea with Adaptive Servoventilation in Chronic Heart Failure. Am J Respir Crit Care Med. 2015 Jul 15; 192(2):132-3. PMID: 26082979.
        View in: PubMed
      50. Mukherjee S, Patel SR, Kales SN, Ayas NT, Strohl KP, Gozal D, Malhotra A. An Official American Thoracic Society Statement: The Importance of Healthy Sleep. Recommendations and Future Priorities. Am J Respir Crit Care Med. 2015 Jun 15; 191(12):1450-8. PMID: 26075423.
        View in: PubMed
      51. Altintas N, Mutlu LC, Akkoyun DC, Aydin M, Bilir B, Yilmaz A, Malhotra A. Effect of CPAP on New Endothelial Dysfunction Marker, Endocan, in People With Obstructive Sleep Apnea. Angiology. 2016 Apr; 67(4):364-74. PMID: 26076702.
        View in: PubMed
      52. Malhotra A, Patil S, Sands S, Ayas N. Central sleep apnoea in congestive heart failure. Lancet Respir Med. 2015 Jul; 3(7):507-8. PMID: 26074186.
        View in: PubMed
      53. Owens RL, Edwards BA, Eckert DJ, Jordan AS, Sands SA, Malhotra A, White DP, Loring SH, Butler JP, Wellman A. An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy. Sleep. 2015; 38(6):961-70. PMID: 25515107.
        View in: PubMed
      54. Smales ET, Edwards BA, Deyoung PN, McSharry DG, Wellman A, Velasquez A, Owens R, Orr JE, Malhotra A. Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold. Ann Am Thorac Soc. 2015 May; 12(5):758-64. PMID: 25719754.
        View in: PubMed
      55. Beitler JR, Thompson BT, Matthay MA, Talmor D, Liu KD, Zhuo H, Hayden D, Spragg RG, Malhotra A. Estimating dead-space fraction for secondary analyses of acute respiratory distress syndrome clinical trials. Crit Care Med. 2015 May; 43(5):1026-35. PMID: 25738857.
        View in: PubMed
      56. Li Y, Daniels LB, Strollo PJ, Malhotra A. Should All Congestive Heart Failure Patients Have a Routine Sleep Apnea Screening? Con. Can J Cardiol. 2015 Jul; 31(7):940-4. PMID: 26112304.
        View in: PubMed
      57. Malhotra A, Orr JE, Owens RL. On the cutting edge of obstructive sleep apnoea: where next? Lancet Respir Med. 2015 May; 3(5):397-403. PMID: 25887980.
        View in: PubMed
      58. Corey KE, Misdraji J, Gelrud L, King LY, Zheng H, Malhotra A, Chung RT. Obstructive Sleep Apnea Is Associated with Nonalcoholic Steatohepatitis and Advanced Liver Histology. Dig Dis Sci. 2015 Aug; 60(8):2523-8. PMID: 25840922.
        View in: PubMed
      59. Kim T, Lee CS, Lee SD, Kang SH, Han JW, Malhotra A, Kim KW, Yoon IY. Impacts of Comorbidities on the Association between Arterial Stiffness and Obstructive Sleep Apnea in the Elderly. Respiration. 2015; 89(4):304-11. PMID: 25790940.
        View in: PubMed
      60. Raisinghani A, Jen R, Wilson J, Malhotra A. Obstructive Sleep Apnea Effects on the Right Ventricle and Beyond. Can J Cardiol. 2015 Jul; 31(7):821-2. PMID: 26112298.
        View in: PubMed
      61. Djonlagic I, Guo M, Matteis P, Carusona A, Stickgold R, Malhotra A. First night of CPAP: impact on memory consolidation attention and subjective experience. Sleep Med. 2015 Jun; 16(6):697-702. PMID: 25953301.
        View in: PubMed
      62. Loring SH, Malhotra A. Driving pressure and respiratory mechanics in ARDS. N Engl J Med. 2015 Feb 19; 372(8):776-7. PMID: 25693019.
        View in: PubMed
      63. Jen R, Grandner MA, Malhotra A. Future of Sleep-Disordered Breathing Therapy Using a Mechanistic Approach. Can J Cardiol. 2015 Jul; 31(7):880-8. PMID: 26044800.
        View in: PubMed
      64. Feliciano A, Torres VM, Vaz F, Carvalho AS, Matthiesen R, Pinto P, Malhotra A, Bárbara C, Penque D. Overview of proteomics studies in obstructive sleep apnea. Sleep Med. 2015 Apr; 16(4):437-45. PMID: 25770042.
        View in: PubMed
      65. Darquenne C, Hicks CB, Malhotra A. Last Word on Viewpoint: The ongoing need for good physiological investigation: Obstructive sleep apnea in HIV patients as a paradigm. J Appl Physiol (1985). 2015 Jan 15; 118(2):251. PMID: 25593221.
        View in: PubMed
      66. Edwards BA, Eckert DJ, McSharry DG, Sands SA, Desai A, Kehlmann G, Bakker JP, Genta PR, Owens RL, White DP, Wellman A, Malhotra A. Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Dec 1; 190(11):1293-300. PMID: 25321848.
        View in: PubMed
      67. Beitler JR, Awad KM, Bakker JP, Edwards BA, DeYoung P, Djonlagic I, Forman DE, Quan SF, Malhotra A. Obstructive sleep apnea is associated with impaired exercise capacity: a cross-sectional study. J Clin Sleep Med. 2014; 10(11):1199-204. PMID: 25325602.
        View in: PubMed
      68. Malhotra A, Neilan TG, Sarmiento K. Obstructive sleep apnea and atrial fibrillation: is the link real? J Am Coll Cardiol. 2014 Nov 11; 64(19):2024-5. PMID: 25440098.
        View in: PubMed
      69. Terrill PI, Edwards BA, Nemati S, Butler JP, Owens RL, Eckert DJ, White DP, Malhotra A, Wellman A, Sands SA. Quantifying the ventilatory control contribution to sleep apnoea using polysomnography. Eur Respir J. 2015 Feb; 45(2):408-18. PMID: 25323235.
        View in: PubMed
      70. Sands SA, Eckert DJ, Jordan AS, Edwards BA, Owens RL, Butler JP, Schwab RJ, Loring SH, Malhotra A, White DP, Wellman A. Enhanced Upper-Airway Muscle Responsiveness Is a Distinct Feature of Overweight/Obese Individuals without Sleep Apnea. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):930-7. PMID: 25191791.
        View in: PubMed
      71. Genta PR, Schorr F, Eckert DJ, Gebrim E, Kayamori F, Moriya HT, Malhotra A, Lorenzi-Filho G. Upper airway collapsibility is associated with obesity and hyoid position. Sleep. 2014 Oct; 37(10):1673-8. PMID: 25197805.
        View in: PubMed
      72. Nemati S, Orr J, Malhotra A. Data-driven phenotyping : graphical models for model-based phenotyping of sleep apnea. IEEE Pulse. 2014 Sep-Oct; 5(5):45-8. PMID: 25437474.
        View in: PubMed
      73. Dudley KA, Malhotra A, Owens RL. Pulmonary Overlap Syndromes, with a focus on COPD and ILD. Sleep Med Clin. 2014 Sep; 9(3):365-379. PMID: 26664352.
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      74. Hubmayr RD, Malhotra A. Still Looking for Best PEEP. Anesthesiology. 2014 Sep; 121(3):445-6. PMID: 25050574.
        View in: PubMed
      75. Darquenne C, Hicks CB, Malhotra A. The ongoing need for good physiological investigation: obstructive sleep apnea in HIV patients as a paradigm. J Appl Physiol (1985). 2015 Jan 15; 118(2):244-6. PMID: 25150224.
        View in: PubMed
      76. Neilan TG, Bakker JP, Sharma B, Owens RL, Farhad H, Shah RV, Abbasi SA, Kohli P, Wilson J, DeMaria A, Jerosch-Herold M, Kwong RY, Malhotra A. T1 measurements for detection of expansion of the myocardial extracellular volume in chronic obstructive pulmonary disease. Can J Cardiol. 2014 Dec; 30(12):1668-75. PMID: 25442461.
        View in: PubMed
      77. Edwards BA, Sands SA, Owens RL, White DP, Genta PR, Butler JP, Malhotra A, Wellman A. Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea. J Physiol. 2014 Oct 15; 592(Pt 20):4523-35. PMID: 25085887.
        View in: PubMed
      78. Ayas NT, Hirsch AA, Laher I, Bradley TD, Malhotra A, Polotsky VY, Tasali E. New frontiers in obstructive sleep apnoea. Clin Sci (Lond). 2014 Aug; 127(4):209-16. PMID: 24780001.
        View in: PubMed
      79. Genta PR, Owens RL, Edwards BA, Sands SA, Eckert DJ, Butler JP, Loring SH, Malhotra A, Jackson AC, White DP, Wellman A. Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway. Respir Physiol Neurobiol. 2014 Sep 15; 201:55-9. PMID: 25020212.
        View in: PubMed
      80. Edwards BA, Wellman A, Sands SA, Owens RL, Eckert DJ, White DP, Malhotra A. Obstructive Sleep Apnea in Older Adults is a Distinctly Different Physiological Phenotype. Sleep. 2014; 37(7):1227-36. PMID: 25061251.
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      81. Batool-Anwar S, Kales SN, Patel SR, Varvarigou V, DeYoung PN, Malhotra A. Obstructive sleep apnea and psychomotor vigilance task performance. Nat Sci Sleep. 2014; 6:65-71. PMID: 24920941.
        View in: PubMed
      82. Ye L, Malhotra A, Kayser K, Willis DG, Horowitz JA, Aloia MS, Weaver TE. Spousal involvement and CPAP adherence: a dyadic perspective. Sleep Med Rev. 2015 Feb; 19:67-74. PMID: 24906222; NIHMSID: NIHMS593288.
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      83. Orr J, Javaheri S, Malhotra A. Comparative effectiveness research in complex sleep apnea. Sleep. 2014; 37(5):833-4. PMID: 24790259.
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      84. Malhotra A, Deacon N, Powell F, Katz ES. Adaptive responses using obstructive sleep apnea as the paradigm. Physiology (Bethesda). 2014 May; 29(3):153-5. PMID: 24789977.
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      85. Bakker JP, Edwards BA, Gautam SP, Montesi SB, Durán-Cantolla J, Barandiarán FA, Barbé F, Sánchez-de-la-Torre M, Malhotra A. Blood Pressure Improvement with Continuous Positive Airway Pressure is Independent of Obstructive Sleep Apnea Severity. J Clin Sleep Med. 2014; 10(4):365-9. PMID: 24733980.
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      86. Eckert DJ, Malhotra A, Wellman A, White DP. Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold. Sleep. 2014; 37(4):811-9. PMID: 24899767.
        View in: PubMed
      87. Bakker JP, Campana LM, Montesi SB, Balachandran J, Deyoung PN, Smales E, Patel SR, Malhotra A. A pilot study investigating the effects of continuous positive airway pressure treatment and weight-loss surgery on autonomic activity in obese obstructive sleep apnea patients. J Electrocardiol. 2014 May-Jun; 47(3):364-73. PMID: 24636793.
        View in: PubMed
      88. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Reply: arousal threshold in obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Feb 1; 189(3):373-4. PMID: 24484350.
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      89. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway. J Appl Physiol (1985). 2014 Apr; 116(8):1105-12. PMID: 24458746.
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      90. Beitler JR, Shaefi S, Montesi SB, Devlin A, Loring SH, Talmor D, Malhotra A. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Med. 2014 Mar; 40(3):332-41. PMID: 24435203.
        View in: PubMed
      91. Shah RV, Abbasi SA, Heydari B, Farhad H, Dodson JA, Bakker JP, John RM, Veves A, Malhotra A, Blankstein R, Jerosch-Herold M, Kwong RY, Neilan TG. Obesity and sleep apnea are independently associated with adverse left ventricular remodeling and clinical outcome in patients with atrial fibrillation and preserved ventricular function. Am Heart J. 2014 Apr; 167(4):620-6. PMID: 24655713.
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      92. Malhotra A. Hypoglossal-nerve stimulation for obstructive sleep apnea. N Engl J Med. 2014 Jan 9; 370(2):170-1. PMID: 24401056.
        View in: PubMed
      93. Neilan TG, Farhad H, Dodson JA, Shah RV, Abbasi SA, Bakker JP, Michaud GF, van der Geest R, Blankstein R, Steigner M, John RM, Jerosch-Herold M, Malhotra A, Kwong RY. Effect of sleep apnea and continuous positive airway pressure on cardiac structure and recurrence of atrial fibrillation. J Am Heart Assoc. 2013; 2(6):e000421. PMID: 24275628.
        View in: PubMed
      94. Deyoung PN, Bakker JP, Sands SA, Batool-Anwar S, Connolly JG, Butler JP, Malhotra A. Acoustic pharyngometry measurement of minimal cross-sectional airway area is a significant independent predictor of moderate-to-severe obstructive sleep apnea. J Clin Sleep Med. 2013; 9(11):1161-4. PMID: 24235897.
        View in: PubMed
      95. Montesi SB, Bakker JP, Macdonald M, Hueser L, Pittman S, White DP, Malhotra A. Air Leak during CPAP Titration as a Risk Factor for Central Apnea. J Clin Sleep Med. 2013; 9(11):1187-91. PMID: 24235901.
        View in: PubMed
      96. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):996-1004. PMID: 23721582.
        View in: PubMed
      97. Kezirian EJ, Goding GS, Malhotra A, O'Donoghue FJ, Zammit G, Wheatley JR, Catcheside PG, Smith PL, Schwartz AR, Walsh JH, Maddison KJ, Claman DM, Huntley T, Park SY, Campbell MC, Palme CE, Iber C, Eastwood PR, Hillman DR, Barnes M. Hypoglossal nerve stimulation improves obstructive sleep apnea: 12-month outcomes. J Sleep Res. 2014 Feb; 23(1):77-83. PMID: 24033656.
        View in: PubMed
      98. Schwab RJ, Badr SM, Epstein LJ, Gay PC, Gozal D, Kohler M, Lévy P, Malhotra A, Phillips BA, Rosen IM, Strohl KP, Strollo PJ, Weaver EM, Weaver TE. An official American Thoracic Society statement: continuous positive airway pressure adherence tracking systems. The optimal monitoring strategies and outcome measures in adults. Am J Respir Crit Care Med. 2013 Sep 1; 188(5):613-20. PMID: 23992588.
        View in: PubMed
      99. Shaw ND, Goodwin JL, Silva GE, Hall JE, Quan SF, Malhotra A. Obstructive sleep apnea (OSA) in preadolescent girls is associated with delayed breast development compared to girls without OSA. J Clin Sleep Med. 2013; 9(8):813-8. PMID: 23946712.
        View in: PubMed
      100. Stanchina ML, Welicky LM, Donat W, Lee D, Corrao W, Malhotra A. Impact of CPAP use and age on mortality in patients with combined COPD and obstructive sleep apnea: the overlap syndrome. J Clin Sleep Med. 2013; 9(8):767-72. PMID: 23946706.
        View in: PubMed
      101. Jordan AS, McSharry DG, Malhotra A. Adult obstructive sleep apnoea. Lancet. 2014 Feb 22; 383(9918):736-47. PMID: 23910433.
        View in: PubMed
      102. Edwards BA, Malhotra A, Sands SA. Adapting our approach to treatment-emergent central sleep apnea. Sleep. 2013 Aug; 36(8):1121-2. PMID: 23904668.
        View in: PubMed
      103. Kaczmarek E, Bakker JP, Clarke DN, Csizmadia E, Kocher O, Veves A, Tecilazich F, O'Donnell CP, Ferran C, Malhotra A. Molecular biomarkers of vascular dysfunction in obstructive sleep apnea. PLoS One. 2013; 8(7):e70559. PMID: 23923005.
        View in: PubMed
      104. Colrain IM, Black J, Siegel LC, Bogan RK, Becker PM, Farid-Moayer M, Goldberg R, Lankford DA, Goldberg AN, Malhotra A. A multicenter evaluation of oral pressure therapy for the treatment of obstructive sleep apnea. Sleep Med. 2013 Sep; 14(9):830-7. PMID: 23871259.
        View in: PubMed
      105. Ayas NT, Malhotra A, Parthsarathy S. To sleep, or not to sleep, that is the question. Crit Care Med. 2013 Jul; 41(7):1808-10. PMID: 23774343.
        View in: PubMed
      106. Nemati S, Edwards BA, Lee J, Pittman-Polletta B, Butler JP, Malhotra A. Respiration and heart rate complexity: effects of age and gender assessed by band-limited transfer entropy. Respir Physiol Neurobiol. 2013 Oct 1; 189(1):27-33. PMID: 23811194.
        View in: PubMed
      107. Beitler JR, Hubmayr RD, Malhotra A. CrossTalk opposing view: there is not added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol. 2013 Jun 1; 591(Pt 11):2767-9. PMID: 23729791.
        View in: PubMed
      108. Ginosar Y, Malhotra A, Schwartz E. High altitude, continuous positive airway pressure, and obstructive sleep apnea: subjective observations and objective data. High Alt Med Biol. 2013 Jun; 14(2):186-9. PMID: 23795742.
        View in: PubMed
      109. Chesson AL, Chervin RD, Benca RM, Greenough GP, O'Hearn DJ, Auckley DH, Littner M, Mullington JM, Malhotra A, Berry RB, Malhotra RK, Schulman DA. Organization and structure for sleep medicine programs at academic institutions: part 2-goals and strategies to optimize patient care, education, and discovery. Sleep. 2013 Jun; 36(6):803-11. PMID: 23729919.
        View in: PubMed
      110. Kohli P, Sarmiento K, Malhotra A. Update in sleep medicine 2012. Am J Respir Crit Care Med. 2013 May 15; 187(10):1056-60. PMID: 23675714.
        View in: PubMed
      111. Plataki M, Sands SA, Malhotra A. Clinical consequences of altered chemoreflex control. Respir Physiol Neurobiol. 2013 Nov 1; 189(2):354-63. PMID: 23681082.
        View in: PubMed
      112. Butler JP, Owens RL, Malhotra A, Wellman A. CrossTalk opposing view: the human upper airway during sleep does not behave like a Starling resistor. J Physiol. 2013 May 1; 591(Pt 9):2233-4. PMID: 23740880.
        View in: PubMed
      113. Butler JP, Owens RL, Malhotra A, Wellman A. Rebuttal from James P. Butler, Robert L. Owens, Atul Malhotra and Andrew Wellman. J Physiol. 2013 May 1; 591(Pt 9):2237. PMID: 23740882.
        View in: PubMed
      114. Chang SY, Dabbagh O, Gajic O, Patrawalla A, Elie MC, Talmor DS, Malhotra A, Adesanya A, Anderson HL, Blum JM, Park PK, Gong MN. Contemporary ventilator management in patients with and at risk of ALI/ARDS. Respir Care. 2013 Apr; 58(4):578-88. PMID: 22906363.
        View in: PubMed
      115. Edwards BA, Connolly JG, Campana LM, Sands SA, Trinder JA, White DP, Wellman A, Malhotra A. Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea. Sleep. 2013 Feb; 36(2):281-5. PMID: 23372276.
        View in: PubMed
      116. Wellman A, Edwards BA, Sands SA, Owens RL, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453.
        View in: PubMed
      117. Bakker JP, Montesi SB, Malhotra A. Obstructive sleep apnoea: new associations and approaches. Lancet Respir Med. 2013 Mar; 1(1):e15-6. PMID: 24321811.
        View in: PubMed
      118. Shaikh ZF, Jaye J, Ward N, Malhotra A, de Villa M, Polkey MI, Mullen MJ, Morrell MJ. Patent foramen ovale in severe obstructive sleep apnea: clinical features and effects of closure. Chest. 2013 Jan; 143(1):56-63. PMID: 22924163.
        View in: PubMed
      119. Sharma B, Neilan TG, Kwong RY, Mandry D, Owens RL, McSharry D, Bakker JP, Malhotra A. Evaluation of right ventricular remodeling using cardiac magnetic resonance imaging in co-existent chronic obstructive pulmonary disease and obstructive sleep apnea. COPD. 2013 Feb; 10(1):4-10. PMID: 23272670.
        View in: PubMed
      120. Zhang C, Berger M, Malhotra A, Kales SN. Portable diagnostic devices for identifying obstructive sleep apnea among commercial motor vehicle drivers: considerations and unanswered questions. Sleep. 2012 Nov; 35(11):1481-9. PMID: 23115397.
        View in: PubMed
      121. Montesi SB, Edwards BA, Malhotra A, Bakker JP. The effect of continuous positive airway pressure treatment on blood pressure: a systematic review and meta-analysis of randomized controlled trials. J Clin Sleep Med. 2012 Oct 15; 8(5):587-96. PMID: 23066375.
        View in: PubMed
      122. Hibbert K, Rice M, Malhotra A. Obesity and ARDS. Chest. 2012 Sep; 142(3):785-90. PMID: 22948584.
        View in: PubMed
      123. Montesi SB, Bajwa EK, Malhotra A. Biomarkers of sleep apnea. Chest. 2012 Jul; 142(1):239-45. PMID: 22796846.
        View in: PubMed
      124. Strohl KP, Butler JP, Malhotra A. Mechanical properties of the upper airway. Compr Physiol. 2012 Jul; 2(3):1853-72. PMID: 23723026.
        View in: PubMed
      125. Altintas N, Aslan E, Helvaci A, Malhotra A. Relationship between obstructive sleep apnea severity index and left ventricular function and volume. Ann Saudi Med. 2012 Jul-Aug; 32(4):384-90. PMID: 22705609.
        View in: PubMed
      126. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. Upper airway collapsibility and patterns of flow limitation at constant end-expiratory lung volume. J Appl Physiol (1985). 2012 Sep 1; 113(5):691-9. PMID: 22628372.
        View in: PubMed
      127. Owens RL, Campana LM, Hess L, Eckert DJ, Loring SH, Malhotra A. Sitting and supine esophageal pressures in overweight and obese subjects. Obesity (Silver Spring). 2012 Dec; 20(12):2354-60. PMID: 22695479.
        View in: PubMed
      128. Owens RL, Edwards BA, Malhotra A, Wellman A. Expiratory resistance increases end-expiratory lung volume during sleep. Am J Respir Crit Care Med. 2012 Apr 15; 185(8):e10-1. PMID: 22505761.
        View in: PubMed
      129. Bakker JP, Sharma B, Malhotra A. Obstructive sleep apnea: the elephant in the cardiovascular room. Chest. 2012 Mar; 141(3):580-1. PMID: 22396556.
        View in: PubMed
      130. Powell ED, Gay PC, Ojile JM, Litinski M, Malhotra A. A pilot study assessing adherence to auto-bilevel following a poor initial encounter with CPAP. J Clin Sleep Med. 2012 Feb 15; 8(1):43-7. PMID: 22334808.
        View in: PubMed
      131. Edwards BA, Sands SA, Eckert DJ, White DP, Butler JP, Owens RL, Malhotra A, Wellman A. Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea. J Physiol. 2012 Mar 1; 590(Pt 5):1199-211. PMID: 22219335.
        View in: PubMed
      132. Schwartz AR, Barnes M, Hillman D, Malhotra A, Kezirian E, Smith PL, Hoegh T, Parrish D, Eastwood PR. Acute upper airway responses to hypoglossal nerve stimulation during sleep in obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 15; 185(4):420-6. PMID: 22135343.
        View in: PubMed
      133. Varvarigou V, Dahabreh IJ, Malhotra A, Kales SN. A review of genetic association studies of obstructive sleep apnea: field synopsis and meta-analysis. Sleep. 2011 Nov; 34(11):1461-8. PMID: 22043116.
        View in: PubMed
      134. Eastwood PR, Barnes M, Walsh JH, Maddison KJ, Hee G, Schwartz AR, Smith PL, Malhotra A, McEvoy RD, Wheatley JR, O'Donoghue FJ, Rochford PD, Churchward T, Campbell MC, Palme CE, Robinson S, Goding GS, Eckert DJ, Jordan AS, Catcheside PG, Tyler L, Antic NA, Worsnop CJ, Kezirian EJ, Hillman DR. Treating obstructive sleep apnea with hypoglossal nerve stimulation. Sleep. 2011 Nov; 34(11):1479-86. PMID: 22043118.
        View in: PubMed
      135. Saboisky JP, Stashuk DW, Hamilton-Wright A, Carusona AL, Campana LM, Trinder J, Eckert DJ, Jordan AS, McSharry DG, White DP, Nandedkar S, David WS, Malhotra A. Neurogenic changes in the upper airway of patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 1; 185(3):322-9. PMID: 22016445.
        View in: PubMed
      136. Balachandran JS, Bakker JP, Rahangdale S, Yim-Yeh S, Mietus JE, Goldberger AL, Malhotra A. Effect of mild, asymptomatic obstructive sleep apnea on daytime heart rate variability and impedance cardiography measurements. Am J Cardiol. 2012 Jan 1; 109(1):140-5. PMID: 21945139.
        View in: PubMed
      137. Bertisch SM, Schomer A, Kelly EE, Baloa LA, Hueser LE, Pittman SD, Malhotra A. Device-guided paced respiration as an adjunctive therapy for hypertension in obstructive sleep apnea: a pilot feasibility study. Appl Psychophysiol Biofeedback. 2011 Sep; 36(3):173-9. PMID: 21523471.
        View in: PubMed
      138. Eckert DJ, Lo YL, Saboisky JP, Jordan AS, White DP, Malhotra A. Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea. J Appl Physiol (1985). 2011 Dec; 111(6):1644-53. PMID: 21885797.
        View in: PubMed
      139. Jordan AS, Eckert DJ, Wellman A, Trinder JA, Malhotra A, White DP. Termination of respiratory events with and without cortical arousal in obstructive sleep apnea. Am J Respir Crit Care Med. 2011 Nov 15; 184(10):1183-91. PMID: 21836132.
        View in: PubMed
      140. Eckert DJ, Owens RL, Kehlmann GB, Wellman A, Rahangdale S, Yim-Yeh S, White DP, Malhotra A. Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold. Clin Sci (Lond). 2011 Jun; 120(12):505-14. PMID: 21269278.
        View in: PubMed
      141. Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI, Frelinger AL, Michelson AD, Malhotra A. The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. J Clin Sleep Med. 2011 Apr 15; 7(2):172-8. PMID: 21509332.
        View in: PubMed
      142. Nemati S, Edwards BA, Sands SA, Berger PJ, Wellman A, Verghese GC, Malhotra A, Butler JP. Model-based characterization of ventilatory stability using spontaneous breathing. J Appl Physiol (1985). 2011 Jul; 111(1):55-67. PMID: 21474696.
        View in: PubMed
      143. Kohli P, Balachandran JS, Malhotra A. Obstructive sleep apnea and the risk for cardiovascular disease. Curr Atheroscler Rep. 2011 Apr; 13(2):138-46. PMID: 21253882.
        View in: PubMed
      144. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens RL, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459.
        View in: PubMed
      145. Owens RL, Wellman A, Malhotra A. Which OSA Patients Might Respond to Nasal Valves? J Clin Sleep Med. 2011 Feb 15; 7(1):23-4. PMID: 21344055.
        View in: PubMed
      146. Mostafiz W, Dalci O, Sutherland K, Malhotra A, Srinivasan V, Darendeliler MA, Cistulli PA. Influence of oral and craniofacial dimensions on mandibular advancement splint treatment outcome in patients with obstructive sleep apnea. Chest. 2011 Jun; 139(6):1331-9. PMID: 21292761.
        View in: PubMed
      147. Sharma B, Feinsilver S, Owens RL, Malhotra A, McSharry D, Karbowitz S. Obstructive airway disease and obstructive sleep apnea: effect of pulmonary function. Lung. 2011 Feb; 189(1):37-41. PMID: 21132554.
        View in: PubMed
      148. Owens RL, Malhotra A. Sleep-disordered breathing and COPD: the overlap syndrome. Respir Care. 2010 Oct; 55(10):1333-44; discussion 1344-6. PMID: 20875160.
        View in: PubMed
      149. Torelli F, Moscufo N, Garreffa G, Placidi F, Romigi A, Zannino S, Bozzali M, Fasano F, Giulietti G, Djonlagic I, Malhotra A, Marciani MG, Guttmann CR. Cognitive profile and brain morphological changes in obstructive sleep apnea. Neuroimage. 2011 Jan 15; 54(2):787-93. PMID: 20888921.
        View in: PubMed
      150. Yim-Yeh S, Rahangdale S, Nguyen AT, Jordan AS, Novack V, Veves A, Malhotra A. Obstructive sleep apnea and aging effects on macrovascular and microcirculatory function. Sleep. 2010 Sep; 33(9):1177-83. PMID: 20857864.
        View in: PubMed
      151. Malhotra A, Owens RL. What is central sleep apnea? Respir Care. 2010 Sep; 55(9):1168-78. PMID: 20799999.
        View in: PubMed
      152. Kezirian EJ, Malhotra A, Goldberg AN, White DP. Changes in obstructive sleep apnea severity, biomarkers, and quality of life after multilevel surgery. Laryngoscope. 2010 Jul; 120(7):1481-8. PMID: 20564750.
        View in: PubMed
      153. Gladysheva ES, Malhotra A, Owens RL. Influencing the decline of lung function in COPD: use of pharmacotherapy. Int J Chron Obstruct Pulmon Dis. 2010; 5:153-64. PMID: 20631815.
        View in: PubMed
      154. Yim-Yeh S, Rahangdale S, Nguyen AT, Stevenson KE, Novack V, Veves A, Malhotra A. Vascular dysfunction in obstructive sleep apnea and type 2 diabetes mellitus. Obesity (Silver Spring). 2011 Jan; 19(1):17-22. PMID: 20523303.
        View in: PubMed
      155. Jordan AS, White DP, Owens RL, Eckert DJ, Rahangdale S, Yim-Yeh S, Malhotra A. The effect of increased genioglossus activity and end-expiratory lung volume on pharyngeal collapse. J Appl Physiol (1985). 2010 Aug; 109(2):469-75. PMID: 20507968.
        View in: PubMed
      156. Sharma B, Owens R, Malhotra A. Sleep in congestive heart failure. Med Clin North Am. 2010 May; 94(3):447-64. PMID: 20451026.
        View in: PubMed
      157. Campana L, Eckert DJ, Patel SR, Malhotra A. Pathophysiology & genetics of obstructive sleep apnoea. Indian J Med Res. 2010 Feb; 131:176-87. PMID: 20308743.
        View in: PubMed
      158. Eastwood PR, Malhotra A, Palmer LJ, Kezirian EJ, Horner RL, Ip MS, Thurnheer R, Antic NA, Hillman DR. Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions. Respirology. 2010 May; 15(4):587-95. PMID: 20136736.
        View in: PubMed
      159. Owens RL, Malhotra A, Eckert DJ, White DP, Jordan AS. The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. J Appl Physiol (1985). 2010 Feb; 108(2):445-51. PMID: 19940097.
        View in: PubMed
      160. Owens RL, Harris RS, Malhotra A. Is the way to man's heart (and lung) through the abdomen? Crit Care. 2009; 13(6):199. PMID: 19909491.
        View in: PubMed
      161. Owens R, Wellman A, Malhotra A. The chicken-or-egg debate in OSA pathogenesis. Sleep. 2009 Oct; 32(10):1255-6. PMID: 19848354.
        View in: PubMed
      162. Saboisky JP, Chamberlin NL, Malhotra A. Potential therapeutic targets in obstructive sleep apnoea. Expert Opin Ther Targets. 2009 Jul; 13(7):795-809. PMID: 19530985.
        View in: PubMed
      163. Epstein LJ, Kristo D, Strollo PJ, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009 Jun 15; 5(3):263-76. PMID: 19960649.
        View in: PubMed
      164. Atkeson A, Yeh SY, Malhotra A, Jelic S. Endothelial function in obstructive sleep apnea. Prog Cardiovasc Dis. 2009 Mar-Apr; 51(5):351-62. PMID: 19249441.
        View in: PubMed
      165. Jordan AS, White DP, Lo YL, Wellman A, Eckert DJ, Yim-Yeh S, Eikermann M, Smith SA, Stevenson KE, Malhotra A. Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea. Sleep. 2009 Mar; 32(3):361-8. PMID: 19294956.
        View in: PubMed
      166. Malhotra A, Loscalzo J. Sleep and cardiovascular disease: an overview. Prog Cardiovasc Dis. 2009 Jan-Feb; 51(4):279-84. PMID: 19110129.
        View in: PubMed
      167. Eckert DJ, Malhotra A, Lo YL, White DP, Jordan AS. The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep. Chest. 2009 Apr; 135(4):957-64. PMID: 19118266.
        View in: PubMed
      168. Owens RL, Hess DR, Malhotra A, Venegas JG, Harris RS. Effect of the chest wall on pressure-volume curve analysis of acute respiratory distress syndrome lungs. Crit Care Med. 2008 Nov; 36(11):2980-5. PMID: 18824918.
        View in: PubMed
      169. Owens RL, Eckert DJ, Yeh SY, Malhotra A. Upper airway function in the pathogenesis of obstructive sleep apnea: a review of the current literature. Curr Opin Pulm Med. 2008 Nov; 14(6):519-24. PMID: 18812828.
        View in: PubMed
      170. Owens RL, Yim-Yeh S, Malhotra A. Carbon monoxide poisoning, or carbon monoxide protection? Chest. 2008 Nov; 134(5):895-6. PMID: 18988771.
        View in: PubMed
      171. Malhotra A, Bertisch S, Wellman A. Complex sleep apnea: it isn't really a disease. J Clin Sleep Med. 2008 Oct 15; 4(5):406-8. PMID: 18853695.
        View in: PubMed
      172. Yeh SY, Rahangdale S, Malhotra A. Metabolic syndrome, obstructive sleep apnea, and continuous positive airway pressure: a weighty issue. Chest. 2008 Oct; 134(4):675-6. PMID: 18842905.
        View in: PubMed
      173. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: role of loop gain. Respir Physiol Neurobiol. 2008 Jul 31; 162(2):144-51. PMID: 18577470.
        View in: PubMed
      174. Segal Y, Malhotra A, Pillar G. Upper airway length may be associated with the severity of obstructive sleep apnea syndrome. Sleep Breath. 2008 Nov; 12(4):311-6. PMID: 18516636.
        View in: PubMed
      175. Eckert DJ, Malhotra A. Pathophysiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008 Feb 15; 5(2):144-53. PMID: 18250206.
        View in: PubMed
      176. MacDonald M, Fang J, Pittman SD, White DP, Malhotra A. The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers. J Clin Sleep Med. 2008 Feb 15; 4(1):38-42. PMID: 18350960.
        View in: PubMed
      177. Eckert DJ, Saboisky JP, Jordan AS, Malhotra A. Upper airway myopathy is not important in the pathophysiology of obstructive sleep apnea. J Clin Sleep Med. 2007 Oct 15; 3(6):570-3. PMID: 17993036.
        View in: PubMed
      178. Malhotra A. Low-tidal-volume ventilation in the acute respiratory distress syndrome. N Engl J Med. 2007 Sep 13; 357(11):1113-20. PMID: 17855672.
        View in: PubMed
      179. Stanchina ML, Ellison K, Malhotra A, Anderson M, Kirk M, Benser ME, Tosi C, Carlisle C, Millman RP, Buxton A. The impact of cardiac resynchronization therapy on obstructive sleep apnea in heart failure patients: a pilot study. Chest. 2007 Aug; 132(2):433-9. PMID: 17573498.
        View in: PubMed
      180. Jordan AS, Wellman A, Heinzer RC, Lo YL, Schory K, Dover L, Gautam S, Malhotra A, White DP. Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax. 2007 Oct; 62(10):861-7. PMID: 17412778.
        View in: PubMed
      181. Huang Y, White DP, Malhotra A. Use of computational modeling to predict responses to upper airway surgery in obstructive sleep apnea. Laryngoscope. 2007 Apr; 117(4):648-53. PMID: 17415135.
        View in: PubMed
      182. Pittman SD, Pillar G, Berry RB, Malhotra A, MacDonald MM, White DP. Follow-up assessment of CPAP efficacy in patients with obstructive sleep apnea using an ambulatory device based on peripheral arterial tonometry. Sleep Breath. 2006 Sep; 10(3):123-31. PMID: 16586136.
        View in: PubMed
      183. Patel SR, Malhotra A, White DP, Gottlieb DJ, Hu FB. Association between reduced sleep and weight gain in women. Am J Epidemiol. 2006 Nov 15; 164(10):947-54. PMID: 16914506.
        View in: PubMed
      184. Patel SR, Malhotra A, Gottlieb DJ, White DP, Hu FB. Correlates of long sleep duration. Sleep. 2006 Jul; 29(7):881-9. PMID: 16895254.
        View in: PubMed
      185. Malhotra A, Patel S. Lung biopsy in ARDS: is it worth the risk? Crit Care. 2006; 10(4):160. PMID: 16941755.
        View in: PubMed
      186. Malhotra A, Huang Y, Fogel R, Lazic S, Pillar G, Jakab M, Kikinis R, White DP. Aging influences on pharyngeal anatomy and physiology: the predisposition to pharyngeal collapse. Am J Med. 2006 Jan; 119(1):72.e9-14. PMID: 16431197.
        View in: PubMed
      187. Huang Y, White DP, Malhotra A. The impact of anatomic manipulations on pharyngeal collapse: results from a computational model of the normal human upper airway. Chest. 2005 Sep; 128(3):1324-30. PMID: 16162725.
        View in: PubMed
      188. Bajwa EK, Ayas NT, Schulzer M, Mak E, Ryu JH, Malhotra A. Interferon-gamma1b therapy in idiopathic pulmonary fibrosis: a metaanalysis. Chest. 2005 Jul; 128(1):203-6. PMID: 16002936.
        View in: PubMed
      189. Jordan AS, Wellman A, Edwards JK, Schory K, Dover L, MacDonald M, Patel SR, Fogel RB, Malhotra A, White DP. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol (1985). 2005 Nov; 99(5):2020-7. PMID: 15994243.
        View in: PubMed
      190. Aloia MS, Stanchina M, Arnedt JT, Malhotra A, Millman RP. Treatment adherence and outcomes in flexible vs standard continuous positive airway pressure therapy. Chest. 2005 Jun; 127(6):2085-93. PMID: 15947324.
        View in: PubMed
      191. Ting L, Malhotra A. Disorders of sleep: an overview. Prim Care. 2005 Jun; 32(2):305-18, v. PMID: 15935187.
        View in: PubMed
      192. Heinzer RC, Stanchina ML, Malhotra A, Fogel RB, Patel SR, Jordan AS, Schory K, White DP. Lung volume and continuous positive airway pressure requirements in obstructive sleep apnea. Am J Respir Crit Care Med. 2005 Jul 1; 172(1):114-7. PMID: 15817803.
        View in: PubMed
      193. Fogel RB, Trinder J, White DP, Malhotra A, Raneri J, Schory K, Kleverlaan D, Pierce RJ. The effect of sleep onset on upper airway muscle activity in patients with sleep apnoea versus controls. J Physiol. 2005 Apr 15; 564(Pt 2):549-62. PMID: 15695240.
        View in: PubMed
      194. Bajwa EK, Malhotra A, Thompson BT. Methods of monitoring shock. Semin Respir Crit Care Med. 2004 Dec; 25(6):629-44. PMID: 16088506.
        View in: PubMed
      195. Wellman A, Jordan AS, Malhotra A, Fogel RB, Katz ES, Schory K, Edwards JK, White DP. Ventilatory control and airway anatomy in obstructive sleep apnea. Am J Respir Crit Care Med. 2004 Dec 1; 170(11):1225-32. PMID: 15317668.
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      196. Pittman SD, Ayas NT, MacDonald MM, Malhotra A, Fogel RB, White DP. Using a wrist-worn device based on peripheral arterial tonometry to diagnose obstructive sleep apnea: in-laboratory and ambulatory validation. Sleep. 2004 Aug 1; 27(5):923-33. PMID: 15453551.
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      197. Jordan AS, McEvoy RD, Edwards JK, Schory K, Yang CK, Catcheside PG, Fogel RB, Malhotra A, White DP. The influence of gender and upper airway resistance on the ventilatory response to arousal in obstructive sleep apnoea in humans. J Physiol. 2004 Aug 1; 558(Pt 3):993-1004. PMID: 15218069.
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      198. Ayas NT, Patel SR, Malhotra A, Schulzer M, Malhotra M, Jung D, Fleetham J, White DP. Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysis. Sleep. 2004 Mar 15; 27(2):249-53. PMID: 15124718.
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      199. Patel SR, Karmpaliotis D, Ayas NT, Mark EJ, Wain J, Thompson BT, Malhotra A. The role of open-lung biopsy in ARDS. Chest. 2004 Jan; 125(1):197-202. PMID: 14718441.
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      200. Carden K, Malhotra A. The debate about gender differences in obstructive sleep apnea. Sleep Med. 2003 Nov; 4(6):485-7. PMID: 14607341.
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      201. Malhotra A, Muse VV, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-2003. An 82-year-old man with dyspnea and pulmonary abnormalities. N Engl J Med. 2003 Apr 17; 348(16):1574-85. PMID: 12700378.
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      202. Fogel RB, Malhotra A, Dalagiorgou G, Robinson MK, Jakab M, Kikinis R, Pittman SD, White DP. Anatomic and physiologic predictors of apnea severity in morbidly obese subjects. Sleep. 2003 Mar 15; 26(2):150-5. PMID: 12683472.
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      203. Patel SR, White DP, Malhotra A, Stanchina ML, Ayas NT. Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis. Arch Intern Med. 2003 Mar 10; 163(5):565-71. PMID: 12622603.
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      204. Ayas NT, White DP, Manson JE, Stampfer MJ, Speizer FE, Malhotra A, Hu FB. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med. 2003 Jan 27; 163(2):205-9. PMID: 12546611.
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      205. Karmpaliotis D, Kosmidou I, Ingenito EP, Hong K, Malhotra A, Sunday ME, Haley KJ. Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L585-95. PMID: 12169578.
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      206. Malhotra A, White DP. Obstructive sleep apnoea. Lancet. 2002 Jul 20; 360(9328):237-45. PMID: 12133673.
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      207. Stanchina ML, Malhotra A, Fogel RB, Ayas N, Edwards JK, Schory K, White DP. Genioglossus muscle responsiveness to chemical and mechanical stimuli during non-rapid eye movement sleep. Am J Respir Crit Care Med. 2002 Apr 1; 165(7):945-9. PMID: 11934719.
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      208. Malhotra A, Ayas N, Kacmarek R. Prone positioning of patients in acute respiratory failure. N Engl J Med. 2002 Jan 24; 346(4):295-7. PMID: 11811184.
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      209. Malhotra A, Pillar G, Fogel RB, Edwards JK, Ayas N, Akahoshi T, Hess D, White DP. Pharyngeal pressure and flow effects on genioglossus activation in normal subjects. Am J Respir Crit Care Med. 2002 Jan 1; 165(1):71-7. PMID: 11779733.
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