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Michael Madani

TitleProfessor Of Clinical
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9300 Campus Point Drive #7892
La Jolla CA 92037
Phone858-246-0611
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    Dr. Michael Madani is a cardiothoracic surgeon who specializes in pulmonary thromboendarterectomy (PTE), heart and lung transplants, heart valve surgery, cardiac bypass, and surgery for treatment of heart failure. He was named 2006 Physician of the Year at the UC San Diego Medical Center in recognition of his dedication to his patients and the high rate of successful outcomes of his surgeries.

    Dr. Madani received his advanced fellowship training in cardiovascular and thoracic surgery here at UC San Diego. He is certified by both the American Board of Surgery and the American Board of Thoracic Surgery.

    Dr. Madani is Professor and Chief of Cardiovascular & Thoracic Surgery and Director of the Sulpizio Cardiovascular Center - Surgery. He directs the Heart Failure Mechanical Assist Device and Heart Transplantation Program at UC San Diego. He is also Clinical Chief of the Division of Cardiothoracic Surgery and Director of the Surgical Intensive Care Unit at the Veterans Affairs Medical Center in La Jolla.

    Under his leadership, the VA Division of Cardiothoracic Surgery has the highest success rate for cardiothoracic surgery of all VA medical centers in the United States. In 2004, Dr. Madani received the Health Care Provider of the Year Award by the California Veterans of Foreign Wars and was later nominated for the 2004 National Award.

    In the Heart Failure Mechanical Assist Device and Heart Transplantation Program at UC San Diego, Dr. Madani is part of a team of top experts in heart failure, electrophysiology, cardiac imaging and cardiothoracic surgery who care for patients who have advanced heart failure. Dr. Madani is an expert in the mechanical devices that can be implanted to assist the heart in patients who suffer from heart failure, as well as in heart and lung transplantation.

    Dr. Madani and Dr. Stuart Jamieson, Endowed Chair and Distinguished Professor of Surgery, are the two most experienced surgeons in the world in PTE. Their PTE program at UC San Diego is known throughout the world for its experience and its high rate of successful outcomes.

    Dr. Madani is also a specialist in off-pump coronary artery bypass surgery, which is a surgery performed without the use of a heart-lung machine. Known as “beating heart” bypass surgery, this procedure is associated with better surgical success and a shorter recovery time for high-risk patients.

    Dr. Madani contributes his surgical expertise and his time to programs that provide access to heart surgery for children and adults in other nations. In 2001, 2003, and 2004, he served as Invited Surgeon in the Variety Children’s Lifeline program at Roberto del Rio Children’s Hospital in Santiago, Chile. This year, he travels to Mexico and to Cambodia to perform heart surgeries and to train local surgeons in the latest techniques for safe and successful surgical procedures on the heart.

    In his research at UC San Diego, Dr. Madani collaborates with other researchers in Surgery/Cardiothoracic Surgery and in the Division of Cardiology in the UC San Diego Department of Medicine. He recently reported the results of a study of the use of Doppler tissue imaging (DTI) after operation with and without cardiopulmonary bypass, and outcomes of pulmonary endarterectomy for treating extreme thromboembolic pulmonary hypertension. He is a co-investigator in a study of a drug treatment for patients who have chronic thromboembolic pulmonary hypertension. He is also an investigator in a United States multicenter study devoted to establishing and maintaining a data registry on acute myocardial infarction with profound cardiogenic shock supported with ventricular assist devices.

    Dr. Madani speaks both English and Persian.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mahmud E, Madani MM, Kim NH, Poch D, Ang L, Behnamfar O, Patel MP, Auger WR. Chronic Thromboembolic Pulmonary Hypertension: Evolving Therapeutic Approaches for Operable and Inoperable Disease. J Am Coll Cardiol. 2018 May 29; 71(21):2468-2486. PMID: 29793636.
      View in: PubMed
    2. Madani M, Ogo T, Simonneau G. The changing landscape of chronic thromboembolic pulmonary hypertension management. Eur Respir Rev. 2017 Dec 31; 26(146). PMID: 29263176.
      View in: PubMed
    3. Ghofrani HA, Simonneau G, D'Armini AM, Fedullo P, Howard LS, Jaïs X, Jenkins DP, Jing ZC, Madani MM, Martin N, Mayer E, Papadakis K, Richard D, Kim NH. Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study. Lancet Respir Med. 2017 10; 5(10):785-794. PMID: 28919201.
      View in: PubMed
    4. Jenkins D, Madani M, Fadel E, D'Armini AM, Mayer E. Pulmonary endarterectomy in the management of chronic thromboembolic pulmonary hypertension. Eur Respir Rev. 2017 Jan; 26(143). PMID: 28298388.
      View in: PubMed
    5. Madani MM. Surgical Treatment of Chronic Thromboembolic Pulmonary Hypertension: Pulmonary Thromboendarterectomy. Methodist Debakey Cardiovasc J. 2016 Oct-Dec; 12(4):213-218. PMID: 28289496.
      View in: PubMed
    6. Wong DJ, Sampat U, Gibson MA, Auger WR, Madani MM, Daniels LB, Raisinghani AB, DeMaria AN, Blanchard DG. Tricuspid annular plane systolic excursion in chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy. Echocardiography. 2016 Dec; 33(12):1805-1809. PMID: 27600256.
      View in: PubMed
    7. Madani M, Mayer E, Fadel E, Jenkins DP. Pulmonary Endarterectomy. Patient Selection, Technical Challenges, and Outcomes. Ann Am Thorac Soc. 2016 Jul; 13 Suppl 3:S240-7. PMID: 27571005.
      View in: PubMed
    8. Jenkins DP, Biederman A, D'Armini AM, Dartevelle PG, Gan HL, Klepetko W, Lindner J, Mayer E, Madani MM. Operability assessment in CTEPH: Lessons from the CHEST-1 study. J Thorac Cardiovasc Surg. 2016 Sep; 152(3):669-674.e3. PMID: 27083940.
      View in: PubMed
    9. Bates DM, Fernandes TM, Duwe BV, King BO, Banks DA, Test VJ, Fedullo PF, Kim NH, Madani MM, Jamieson SW, Auger WR, Kerr KM. Efficacy of a Low-Tidal Volume Ventilation Strategy to Prevent Reperfusion Lung Injury after Pulmonary Thromboendarterectomy. Ann Am Thorac Soc. 2015 Oct; 12(10):1520-7. PMID: 26241077.
      View in: PubMed
    10. Lee NS, Blanchard DG, Knowlton KU, McDivit AM, Pretorius V, Madani MM, Fedullo PF, Kerr KM, Kim NH, Poch DS, Auger WR, Daniels LB. Prevalence of coronary artery-pulmonary artery collaterals in patients with chronic thromboembolic pulmonary hypertension. Pulm Circ. 2015 Jun; 5(2):313-21. PMID: 26064456; PMCID: PMC4449242.
    11. Grover GN, Garcia J, Nguyen MM, Zanotelli M, Madani MM, Christman KL. Binding of Anticell Adhesive Oxime-Crosslinked PEG Hydrogels to Cardiac Tissues. Adv Healthc Mater. 2015 Jun 24; 4(9):1327-31. PMID: 25963916.
      View in: PubMed
    12. Marston N, Brown JP, Olson N, Auger WR, Madani MM, Wong D, Raisinghani AB, DeMaria AN, Blanchard DG. Right ventricular strain before and after pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension. Echocardiography. 2015 Jul; 32(7):1115-21. PMID: 25327878.
      View in: PubMed
    13. Cronin B, Maus T, Pretorius V, Nguyen L, Johnson D, Ovando J, Auger W, Madani M, Jamieson S, Banks D, Minhaj M, Esper SA, Welsby IJ. Case 13--2014: Management of pulmonary hemorrhage after pulmonary endarterectomy with venovenous extracorporeal membrane oxygenation without systemic anticoagulation. J Cardiothorac Vasc Anesth. 2014 Dec; 28(6):1667-76. PMID: 25440651.
      View in: PubMed
    14. Kim NH, Delcroix M, Jenkins DP, Channick R, Dartevelle P, Jansa P, Lang I, Madani MM, Ogino H, Pengo V, Mayer E. [Chronic thromboembolic pulmonary hypertension]. Turk Kardiyol Dern Ars. 2014 Oct; 42 Suppl 1:119-29. PMID: 25697039.
      View in: PubMed
    15. Fernandes TM, Auger WR, Fedullo PF, Kim NH, Poch DS, Madani MM, Pretorius VG, Jamieson SW, Kerr KM. Baseline body mass index does not significantly affect outcomes after pulmonary thromboendarterectomy. Ann Thorac Surg. 2014 Nov; 98(5):1776-81. PMID: 25240778; PMCID: PMC4254364.
    16. Marston NA, Auger WR, Madani MM, Kimura BJ, Strachan GM, Raisinghani AB, DeMaria AN, Blanchard DG. Assessment of left atrial volume before and after pulmonary thromboendarterectomy in chronic thromboembolic pulmonary hypertension. Cardiovasc Ultrasound. 2014 Aug 11; 12:32. PMID: 25109313; PMCID: PMC4131478.
    17. Lang IM, Madani M. Update on chronic thromboembolic pulmonary hypertension. Circulation. 2014 Aug 05; 130(6):508-18. PMID: 25092279.
      View in: PubMed
    18. Hoeper MM, Madani MM, Nakanishi N, Meyer B, Cebotari S, Rubin LJ. Chronic thromboembolic pulmonary hypertension. Lancet Respir Med. 2014 Jul; 2(7):573-82. PMID: 24898750.
      View in: PubMed
    19. Nguyen L, Banks D, Manecke G, Shurter J, Schilling JM, Patel HH, Madani MM, Roth DM. Plasma vasopressin levels in patients with right-sided heart dysfunction and chronic thromboembolic pulmonary hypertension (CTEPH). J Cardiothorac Vasc Anesth. 2014 Jun; 28(3):601-7. PMID: 24746335.
      View in: PubMed
    20. Kim NH, Delcroix M, Jenkins DP, Channick R, Dartevelle P, Jansa P, Lang I, Madani MM, Ogino H, Pengo V, Mayer E. Chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D92-9. PMID: 24355646.
      View in: PubMed
    21. Xie Y, Burke BM, Kopelnik A, Auger W, Daniels LB, Madani MM, Poch DS, Kim NH, Blanchard DG. Echocardiographic estimation of pulmonary vascular resistance in chronic thromboembolic pulmonary hypertension: utility of right heart Doppler measurements. Echocardiography. 2014; 31(1):29-33. PMID: 23822605.
      View in: PubMed
    22. Kimura BJ, Parise CM, Monet Strachan G, Auger W, Madani MM, Daniels LB, Blanchard DG. Diminished aortic excursion in chronic thromboembolic pulmonary hypertension. Echocardiography. 2013 Nov; 30(10):1126-9. PMID: 23710685.
      View in: PubMed
    23. Jenkins DP, Madani M, Mayer E, Kerr K, Kim N, Klepetko W, Morsolini M, Dartevelle P. Surgical treatment of chronic thromboembolic pulmonary hypertension. Eur Respir J. 2013 Mar; 41(3):735-42. PMID: 23143539.
      View in: PubMed
    24. Mulpuru SK, Feld GK, Madani M, Sawhney NS. A novel, minimally-invasive surgical approach for ablation of ventricular tachycardia originating near the proximal left anterior descending coronary artery. Circ Arrhythm Electrophysiol. 2012 Oct; 5(5):e95-7. PMID: 23074330.
      View in: PubMed
    25. Madani MM, Auger WR, Pretorius V, Sakakibara N, Kerr KM, Kim NH, Fedullo PF, Jamieson SW. Pulmonary endarterectomy: recent changes in a single institution's experience of more than 2,700 patients. Ann Thorac Surg. 2012 Jul; 94(1):97-103; discussion 103. PMID: 22626752.
      View in: PubMed
    26. Madani MM. A clinical commentary on the article "patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair". J Cardiovasc Transl Res. 2011 Oct; 4(5):557-8. PMID: 21877257.
      View in: PubMed
    27. Kerr KM, Auger WR, Marsh JJ, Devendra G, Spragg RG, Kim NH, Channick RN, Jamieson SW, Madani MM, Manecke GR, Roth DM, Shragg GP, Fedullo PF. Efficacy of methylprednisolone in preventing lung injury following pulmonary thromboendarterectomy. Chest. 2012 Jan; 141(1):27-35. PMID: 21835900; PMCID: PMC3251267.
    28. Seif-Naraghi SB, Horn D, Schup-Magoffin PA, Madani MM, Christman KL. Patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair. J Cardiovasc Transl Res. 2011 Oct; 4(5):545-56. PMID: 21695575; PMCID: PMC3280922.
    29. Olson N, Brown JP, Kahn AM, Auger WR, Madani MM, Waltman TJ, Blanchard DG. Left ventricular strain and strain rate by 2D speckle tracking in chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy. Cardiovasc Ultrasound. 2010 Sep 27; 8:43. PMID: 20875129; PMCID: PMC2955577.
    30. Anderson M, Smedira N, Samuels L, Madani M, Naka Y, Acker M, Hout M, Benali K. Use of the AB5000 ventricular assist device in cardiogenic shock after acute myocardial infarction. Ann Thorac Surg. 2010 Sep; 90(3):706-12. PMID: 20732481.
      View in: PubMed
    31. Madani MM, Wittine LM, Auger WR, Fedullo PF, Kerr KM, Kim NH, Test VJ, Kriett JM, Jamieson SW. Chronic thromboembolic pulmonary hypertension in pediatric patients. J Thorac Cardiovasc Surg. 2011 Mar; 141(3):624-30. PMID: 20800245.
      View in: PubMed
    32. Grossfeld P, Greenberg M, Saw S, Cheng G, Stanzi A, Mathewson J, Pises N, Lyda L, Vuthy S, Elias W, Moriarty S, Levy S, Walter D, Panzarella P, Grossfeld S, Kriett J, Madani M. Successful surgical closure of an arterial duct in 18 children in a third world country. Cardiol Young. 2010 Aug; 20(4):367-72. PMID: 20482943.
      View in: PubMed
    33. Jamieson SW, Madani M. Chronic thromboembolic pulmonary hypertension. Ann Vasc Dis. 2009; 2(3):133-5. PMID: 23555372; PMCID: PMC3595741.
    34. Firth AL, Yao W, Ogawa A, Madani MM, Lin GY, Yuan JX. Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Cell Physiol. 2010 May; 298(5):C1217-25. PMID: 20181931; PMCID: PMC2867379.
    35. Nguyen L, Banks D, Madani M, Bulatao J. Case 6--2009. Anesthetic implications of partial left-heart bypass for repair of the descending thoracic aorta. J Cardiothorac Vasc Anesth. 2009 Dec; 23(6):893-900. PMID: 19944354.
      View in: PubMed
    36. Potenza B, Deligencia M, Estigoy B, Faraday E, Snyder A, Angle N, Schwartz A, Chang L, Hackett J, Minokadeh A, Madani M, MacAulay K, Ramamoorthy S, Blaner L, James C, Bansal V, Torriani F, Coimbra R. Lessons learned from the institution of the Surgical Care Improvement Project at a teaching medical center. Am J Surg. 2009 Dec; 198(6):881-8. PMID: 19969146.
      View in: PubMed
    37. Robbins PK, Pye GW, Sutherland-Smith M, Papendick R, Greenberg M, Levy D, Madani M. Successful transabdominal subxiphoid pericardiostomy to relieve chronic pericardial effusion in a Sumatran orangutan (Pongo abelli). J Zoo Wildl Med. 2009 Sep; 40(3):564-7. PMID: 19746874.
      View in: PubMed
    38. Ogawa A, Firth AL, Yao W, Madani MM, Kerr KM, Auger WR, Jamieson SW, Thistlethwaite PA, Yuan JX. Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L666-76. PMID: 19633069; PMCID: PMC2770792.
    39. Yao W, Firth AL, Sacks RS, Ogawa A, Auger WR, Fedullo PF, Madani MM, Lin GY, Sakakibara N, Thistlethwaite PA, Jamieson SW, Rubin LJ, Yuan JX. Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L870-8. PMID: 19286928; PMCID: PMC2692803.
    40. Blanchard DG, Malouf PJ, Gurudevan SV, Auger WR, Madani MM, Thistlethwaite P, Waltman TJ, Daniels LB, Raisinghani AB, DeMaria AN. Utility of right ventricular Tei index in the noninvasive evaluation of chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy. JACC Cardiovasc Imaging. 2009 Feb; 2(2):143-9. PMID: 19356547.
      View in: PubMed
    41. Jamieson SW, Madani M. Invited commentary. Ann Thorac Surg. 2008 Oct; 86(4):1267. PMID: 18805173.
      View in: PubMed
    42. Thistlethwaite PA, Kaneko K, Madani MM, Jamieson SW. Technique and outcomes of pulmonary endarterectomy surgery. Ann Thorac Cardiovasc Surg. 2008 Oct; 14(5):274-82. PMID: 18989242.
      View in: PubMed
    43. Davis BA, Manecke GR, Madani MM. New cardiac mass during cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2008 Oct; 22(5):786-7. PMID: 18922444.
      View in: PubMed
    44. Gurudevan SV, Malouf PJ, Kahn AM, Auger WR, Waltman TJ, Madani M, Demaria AN, Blanchard DG. Noninvasive assessment of pulmonary vascular resistance using Doppler tissue imaging of the tricuspid annulus. J Am Soc Echocardiogr. 2007 Oct; 20(10):1167-71. PMID: 17566699.
      View in: PubMed
    45. Gurudevan SV, Malouf PJ, Auger WR, Waltman TJ, Madani M, Raisinghani AB, DeMaria AN, Blanchard DG. Abnormal left ventricular diastolic filling in chronic thromboembolic pulmonary hypertension: true diastolic dysfunction or left ventricular underfilling? J Am Coll Cardiol. 2007 Mar 27; 49(12):1334-9. PMID: 17394966.
      View in: PubMed
    46. Solum AM, Romero SC, Ledford S, Parker R, Madani MM, Coletta JM. Left atrial hemangioma presenting as cardiac tamponade. Tex Heart Inst J. 2007; 34(1):126-7. PMID: 17420811; PMCID: PMC1847930.
    47. Thistlethwaite PA, Madani MM, Kemp AD, Hartley M, Auger WR, Jamieson SW. Venovenous extracorporeal life support after pulmonary endarterectomy: indications, techniques, and outcomes. Ann Thorac Surg. 2006 Dec; 82(6):2139-45. PMID: 17126125.
      View in: PubMed
    48. Harris B, Manecke GR, Niemann J, Madani M, Jamieson S. Deep hypothermia and the vascular response to thiopental. J Cardiothorac Vasc Anesth. 2006 Oct; 20(5):678-83. PMID: 17023288.
      View in: PubMed
    49. Malouf PJ, Madani M, Gurudevan S, Waltman TJ, Raisinghani AB, DeMaria AN, Blanchard DG. Assessment of diastolic function with Doppler tissue imaging after cardiac surgery: effect of the "postoperative septum" in on-pump and off-pump procedures. J Am Soc Echocardiogr. 2006 Apr; 19(4):464-7. PMID: 16581488.
      View in: PubMed
    50. Thistlethwaite PA, Kemp A, Du L, Madani MM, Jamieson SW. Outcomes of pulmonary endarterectomy for treatment of extreme thromboembolic pulmonary hypertension. J Thorac Cardiovasc Surg. 2006 Feb; 131(2):307-13. PMID: 16434258.
      View in: PubMed
    51. Lee CC, Adamson D, Madani M, Manecke GR. Transesophageal echocardiography and the intraoperative diagnosis of a right pulmonary artery aneurysm. J Cardiothorac Vasc Anesth. 2006 Aug; 20(4):562-4. PMID: 16884989.
      View in: PubMed
    52. Madani MM, Jamieson SW. Technical advances of pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Semin Thorac Cardiovasc Surg. 2006; 18(3):243-9. PMID: 17185187.
      View in: PubMed
    53. Thistlethwaite PA, Madani M, Jamieson SW. Outcomes of pulmonary endarterectomy surgery. Semin Thorac Cardiovasc Surg. 2006; 18(3):257-64. PMID: 17185189.
      View in: PubMed
    54. Thistlethwaite PA, Madani M, Jamieson SW. Pulmonary thromboendarterectomy surgery. Cardiol Clin. 2004 Aug; 22(3):467-78, vii. PMID: 15302365.
      View in: PubMed
    55. Madani MM. Mitral Valve Repair in the Treatment of Heart Failure. Curr Treat Options Cardiovasc Med. 2004 Aug; 6(4):305-311. PMID: 15212725.
      View in: PubMed
    56. Jamieson SW, Madani MM. The choice of valve protheses. J Am Coll Cardiol. 2004 Jul 21; 44(2):389-90. PMID: 15261936.
      View in: PubMed
    57. Hutfless R, Kazanegra R, Madani M, Bhalla MA, Tulua-Tata A, Chen A, Clopton P, James C, Chiu A, Maisel AS. Utility of B-type natriuretic peptide in predicting postoperative complications and outcomes in patients undergoing heart surgery. J Am Coll Cardiol. 2004 May 19; 43(10):1873-9. PMID: 15145114.
      View in: PubMed
    58. Cavendish JJ, Penny WF, Madani MM, Keramati S, Ben-Yehuda O, Blanchard DG, Mahmud E, Perricone A, Tsimikas S. Severe ostial saphenous vein graft disease leading to acute coronary syndromes following proximal aorto-saphenous anastomoses with the symmetry bypass connector device: is it a suture device or a "stent"? J Am Coll Cardiol. 2004 Jan 07; 43(1):133-9. PMID: 14715195.
      View in: PubMed
    59. Thistlethwaite PA, Mo M, Madani MM, Deutsch R, Blanchard D, Kapelanski DP, Jamieson SW. Operative classification of thromboembolic disease determines outcome after pulmonary endarterectomy. J Thorac Cardiovasc Surg. 2002 Dec; 124(6):1203-11. PMID: 12447188.
      View in: PubMed
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