Omar Mesarwi

Title(s)Associate Professor Of Clinical, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Stanford, CAB.S.06/2002Biological sciences
    UT Southwestern School of Medicine, Dallas, TXM.D.06/2007Medicine
    UT Southwestern Medical Center, Dallas, TX06/2010Internal Medicine
    Johns Hopkins University, Baltimore, MD06/2014Pulmonary and Critical Care Medicine
    Johns Hopkins University, Baltimore, MD06/2016Sleep Medicine

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling. Arterioscler Thromb Vasc Biol. 2024 06; 44(6):1246-1264. Frias-Anaya E, Gallego-Gutierrez H, Gongol B, Weinsheimer S, Lai CC, Orecchioni M, Sriram A, Bui CM, Nelsen B, Hale P, Pham A, Shenkar R, DeBiasse D, Lightle R, Girard R, Li Y, Srinath A, Daneman R, Nudleman E, Sun H, Guma M, Dubrac A, Mesarwi OA, Ley K, Kim H, Awad IA, Ginsberg MH, Lopez-Ramirez MA. PMID: 38660801; PMCID: PMC11111348.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Intermittent Versus Sustained Hypoxemia from Sleep-disordered Breathing: Outcomes in Patients with Chronic Lung Disease and High Altitude. Sleep Med Clin. 2024 Jun; 19(2):327-337. Self AA, Mesarwi OA. PMID: 38692756.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Duration of intermittent hypoxia impacts metabolic outcomes and severity of murine NAFLD. Front Sleep. 2023; 2. Barnes LA, Xu Y, Sanchez-Azofra A, Moya EA, Zhang MP, Crotty Alexander LE, Malhotra A, Mesarwi O. PMID: 38077744; PMCID: PMC10704994.
      View in: PubMed   Mentions:
    4. Inflammation biomarkers in OSA, chronic obstructive pulmonary disease, and chronic obstructive pulmonary disease/OSA overlap syndrome. J Clin Sleep Med. 2023 08 01; 19(8):1447-1456. Sanchez-Azofra A, Gu W, Masso-Silva JA, Sanz-Rubio D, Marin-Oto M, Cubero P, Gil AV, Moya EA, Barnes LA, Mesarwi OA, Marin T, Simonson TS, Crotty Alexander LE, Marin JM, Malhotra A. PMID: 37082823; PMCID: PMC10394367.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. How far would you go to sleep better at high altitude? Sleep. 2023 02 08; 46(2). Moya EA, Mesarwi OA. PMID: 36413093; PMCID: PMC9905773.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Obstructive sleep apnea and pulmonary hypertension: the pendulum swings again. J Clin Sleep Med. 2023 02 01; 19(2):209-211. Yang JZ, Mokhlesi B, Mesarwi OA. PMID: 36533401; PMCID: PMC9892742.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease. Circ Res. 2022 11 11; 131(11):909-925. Lai CC, Nelsen B, Frias-Anaya E, Gallego-Gutierrez H, Orecchioni M, Herrera V, Ortiz E, Sun H, Mesarwi OA, Ley K, Gongol B, Lopez-Ramirez MA. PMID: 36285625; PMCID: PMC9669201.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    8. Isovolemic hemodilution in chronic mountain sickness acutely worsens nocturnal oxygenation and sleep apnea severity. J Clin Sleep Med. 2022 10 01; 18(10):2423-2432. Sanchez-Azofra A, Villafuerte FC, DeYoung PN, Gilbertson D, Gu W, Moya EA, Vizcardo-Galindo G, Figueroa-Mujíca R, Anza-Ramirez C, Macarlupú JL, Pham LV, Wagner P, Malhotra A, Simonson TS, Mesarwi OA. PMID: 35855526; PMCID: PMC9516589.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Time Domains of Hypoxia Responses and -Omics Insights. Front Physiol. 2022; 13:885295. Yu JJ, Non AL, Heinrich EC, Gu W, Alcock J, Moya EA, Lawrence ES, Tift MS, O'Brien KA, Storz JF, Signore AV, Khudyakov JI, Milsom WK, Wilson SM, Beall CM, Villafuerte FC, Stobdan T, Julian CG, Moore LG, Fuster MM, Stokes JA, Milner R, West JB, Zhang J, Shyy JY, Childebayeva A, Vázquez-Medina JP, Pham LV, Mesarwi OA, Hall JE, Cheviron ZA, Sieker J, Blood AB, Yuan JX, Scott GR, Rana BK, Ponganis PJ, Malhotra A, Powell FL, Simonson TS. PMID: 36035495; PMCID: PMC9400701.
      View in: PubMed   Mentions: 6  
    10. Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype. Sleep. 2022 06 13; 45(6). Zhen X, Moya EA, Gautane M, Zhao H, Lawrence ES, Gu W, Barnes LA, Yuan JX, Jain PP, Xiong M, Catalan Serra P, Pham LV, Malhotra A, Simonson TS, Mesarwi OA. PMID: 34893914; PMCID: PMC9189937.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    11. The Cardiovascular and Metabolic Effects of Chronic Hypoxia in Animal Models: A Mini-Review. Front Physiol. 2022; 13:873522. Barnes LA, Mesarwi OA, Sanchez-Azofra A. PMID: 35432002; PMCID: PMC9008331.
      View in: PubMed   Mentions: 11  
    12. Hepatocyte HIF-1 and Intermittent Hypoxia Independently Impact Liver Fibrosis in Murine Nonalcoholic Fatty Liver Disease. Am J Respir Cell Mol Biol. 2021 10; 65(4):390-402. Mesarwi OA, Moya EA, Zhen X, Gautane M, Zhao H, Wegbrans Giró P, Alshebli M, McCarley KE, Breen EC, Malhotra A. PMID: 34003729; PMCID: PMC8525205.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    13. Endotypes and phenotypes in obstructive sleep apnea. Curr Opin Pulm Med. 2020 11; 26(6):609-614. Malhotra A, Mesarwi O, Pepin JL, Owens RL. PMID: 32890019; PMCID: PMC7544644.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    14. Obstructive sleep apnea and pulmonary hypertension: a bidirectional relationship. J Clin Sleep Med. 2020 08 15; 16(8):1223-1224. Mesarwi O, Malhotra A. PMID: 32807290; PMCID: PMC7446089.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Obstructive sleep apnea and pulmonary hypertension: a bidirectional relationship. J Clin Sleep Med. 2020 Jun 26. Mesarwi O, Malhotra A. PMID: 32588818.
      View in: PubMed   Mentions:    Fields:    
    16. Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease. Am J Respir Crit Care Med. 2019 04 01; 199(7):830-841. Mesarwi OA, Loomba R, Malhotra A. PMID: 30422676; PMCID: PMC6835083.
      View in: PubMed   Mentions: 100     Fields:    Translation:Humans
    17. A Case of Daytime Sleepiness after Motor Vehicle Collision. Ann Am Thorac Soc. 2019 02; 16(2):265-267. Iizuka Y, Cassidy J, Mesarwi OA. PMID: 30707059.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Putting It Together: Sleep Apnea, the Integrated Stress Response, and Metabolic Dysfunction. Am J Respir Cell Mol Biol. 2017 10; 57(4):391-392. Mesarwi OA, Malhotra A. PMID: 28960107; PMCID: PMC5800894.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    19. Sleep apnea, metabolic disease, and the cutting edge of therapy. Metabolism. 2018 07; 84:94-98. Light M, McCowen K, Malhotra A, Mesarwi OA. PMID: 28966076; PMCID: PMC5874161.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    20. Hepatocyte Hypoxia Inducible Factor-1 Mediates the Development of Liver Fibrosis in a Mouse Model of Nonalcoholic Fatty Liver Disease. PLoS One. 2016; 11(12):e0168572. Mesarwi OA, Shin MK, Bevans-Fonti S, Schlesinger C, Shaw J, Polotsky VY. PMID: 28030556; PMCID: PMC5193414.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    21. Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea. Sleep. 2015 Oct 01; 38(10):1583-91. Mesarwi OA, Shin MK, Drager LF, Bevans-Fonti S, Jun JC, Putcha N, Torbenson MS, Pedrosa RP, Lorenzi-Filho G, Steele KE, Schweitzer MA, Magnuson TH, Lidor AO, Schwartz AR, Polotsky VY. PMID: 26085300; PMCID: PMC4576332.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    22. Metabolic dysfunction in obstructive sleep apnea: A critical examination of underlying mechanisms. Sleep Biol Rhythms. 2015 Jan; 13(1):2-17. Mesarwi OA, Sharma EV, Jun JC, Polotsky VY. PMID: 26412981; PMCID: PMC4583137.
      View in: PubMed   Mentions: 37  
    23. A patient with unusual electroencephalographic findings during rapid eye movement sleep. Ann Am Thorac Soc. 2014 Dec; 11(10):1660-4. Mesarwi OA, Ellenbogen JM, Polotsky VY. PMID: 25549034; PMCID: PMC5475426.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy. Am J Physiol Endocrinol Metab. 2014 Dec 01; 307(11):E1073-83. Jun JC, Shin MK, Devera R, Yao Q, Mesarwi O, Bevans-Fonti S, Polotsky VY. PMID: 25315697; PMCID: PMC4254988.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    25. Carotid body denervation prevents fasting hyperglycemia during chronic intermittent hypoxia. J Appl Physiol (1985). 2014 Oct 01; 117(7):765-76. Shin MK, Yao Q, Jun JC, Bevans-Fonti S, Yoo DY, Han W, Mesarwi O, Richardson R, Fu YY, Pasricha PJ, Schwartz AR, Shirahata M, Polotsky VY. PMID: 25103977; PMCID: PMC4187050.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    26. Sleep disorders and the development of insulin resistance and obesity. Endocrinol Metab Clin North Am. 2013 Sep; 42(3):617-34. Mesarwi O, Polak J, Jun J, Polotsky VY. PMID: 24011890; PMCID: PMC3767932.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    27. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Hum Mol Genet. 2004 Mar 15; 13(6):609-16. Li JZ, Vawter MP, Walsh DM, Tomita H, Evans SJ, Choudary PV, Lopez JF, Avelar A, Shokoohi V, Chung T, Mesarwi O, Jones EG, Watson SJ, Akil H, Bunney WE, Myers RM. PMID: 14734628.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
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