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The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 Dec 09; 14(1):8169.
Tapryal N, Chakraborty A, Saha K, Islam A, Pan L, Hosoki K, Sayed IM, Duran JM, Alcantara J, Castillo V, Tindle C, Sarker AH, Wakamiya M, Cardenas VJ, Sharma G, Crotty Alexander LE, Sur S, Sahoo D, Ghosh G, Das S, Ghosh P, Boldogh I, Hazra TK. PMID: 38071370; PMCID: PMC10710473.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Implementing Holistic Review Practices in a Pulmonary and Critical Care Fellowship. ATS Sch. 2023 Dec; 4(4):528-537.
Bailey J, Desai B, Wang A, Sunwoo B, Kerr K, Mandel J, Crouch DR, Crotty Alexander LE. PMID: 38196677; PMCID: PMC10773494.
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PubMed Mentions:
3
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Duration of intermittent hypoxia impacts metabolic outcomes and severity of murine NAFLD. Front Sleep. 2023; 2.
Barnes LA, Xu Y, Sanchez-Azofra A, Moya EA, Zhang MP, Crotty Alexander LE, Malhotra A, Mesarwi O. PMID: 38077744; PMCID: PMC10704994.
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PubMed Mentions:
-
Inflammation biomarkers in OSA, chronic obstructive pulmonary disease, and chronic obstructive pulmonary disease/OSA overlap syndrome. J Clin Sleep Med. 2023 08 01; 19(8):1447-1456.
Sanchez-Azofra A, Gu W, Masso-Silva JA, Sanz-Rubio D, Marin-Oto M, Cubero P, Gil AV, Moya EA, Barnes LA, Mesarwi OA, Marin T, Simonson TS, Crotty Alexander LE, Marin JM, Malhotra A. PMID: 37082823; PMCID: PMC10394367.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers. Respir Res. 2023 May 18; 24(1):134.
Perez MF, Yurieva M, Poddutoori S, Mortensen EM, Crotty Alexander LE, Williams A. PMID: 37208747; PMCID: PMC10196320.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients. Cell Rep Med. 2023 02 21; 4(2):100935.
Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 36758547; PMCID: PMC9874047.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The E-cigarette or Vaping Product Use-Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2023 01; 20(1):1-17.
Rebuli ME, Rose JJ, Noël A, Croft DP, Benowitz NL, Cohen AH, Goniewicz ML, Larsen BT, Leigh N, McGraw MD, Melzer AC, Penn AL, Rahman I, Upson D, Crotty Alexander LE, Ewart G, Jaspers I, Jordt SE, Kligerman S, Loughlin CE, McConnell R, Neptune ER, Nguyen TB, Pinkerton KE, Witek TJ. PMID: 36584985; PMCID: PMC9819258.
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PubMed Mentions:
16 Fields:
Translation:
HumansPHPublic Health
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A Problem for Generations: Impact of E-Cigarette Type on Immune Homeostasis. Am J Respir Crit Care Med. 2022 11 15; 206(10):1195-1197.
Sullivan L, Crotty Alexander LE. PMID: 35816433; PMCID: PMC9746835.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulin. Front Immunol. 2022; 13:993720.
Masso-Silva JA, Sakoulas G, Olay J, Groysberg V, Geriak M, Nizet V, Crotty Alexander LE, Meier A. PMID: 36341409; PMCID: PMC9632428.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Learning Outcomes in a Live Virtual versus In-Person Curriculum for Medical and Pharmacy Students. ATS Sch. 2022 Oct; 3(3):399-412.
Nilaad SD, Lin E, Bailey J, Truong C, Gaboyan S, Mittal A, Best BM, Guluma K, Iglewicz A, Lander L, Evans S, Goldberg C, Crotty Alexander LE. PMID: 36312802; PMCID: PMC9585697.
View in:
PubMed Mentions:
5
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Electronic Cigarettes: A Pro-Con Review of the Current Literature. J Allergy Clin Immunol Pract. 2022 11; 10(11):2843-2851.
Giovacchini CX, Crotty Alexander LE, Que LG. PMID: 35872217.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansPHPublic Health
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Electronic cigarette use and perceptions during COVID-19. Respir Med. 2022 Aug-Sep; 200:106925.
Merz W, Magraner J, Gunge D, Advani I, Crotty Alexander LE, Oren E. PMID: 35797927; PMCID: PMC9250168.
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PubMed Mentions:
4 Fields:
Translation:
HumansCellsPHPublic Health
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Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association. Circ Res. 2022 07 22; 131(3):e70-e82.
Wold LE, Tarran R, Crotty Alexander LE, Hamburg NM, Kheradmand F, St Helen G, Wu JC, American Heart Association Council on Basic Cardiovascular Sciences; Council on Arteriosclerosis, Th. PMID: 35726609.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Daily E-cigarette Use and the Surge in JUUL Sales: 2017-2019. Pediatrics. 2022 Jun 01; 149(6).
Pierce JP, Zhang J, Crotty Alexander LE, Leas EC, Kealey S, White MM, Strong DR, Trinidad DR, McMenamin SB, Chen R, Benmarhnia T, Messer K. PMID: 35634883; PMCID: PMC9647987.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Correction to: Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 May 30; 74(10):1889-1890.
Masso-Silva JA, Moshensky A, Lam MTY, Odish M, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott R, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 35416961; PMCID: PMC9327099.
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PubMed Mentions:
5 Fields:
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Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. Elife. 2022 04 12; 11.
Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. PMID: 35411847; PMCID: PMC9005188.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Impulsivity-Related Personality Traits as Predictors of E-Cigarette Use among Young Adults over Time. Subst Use Misuse. 2022; 57(7):1007-1013.
Mittal A, Du A, Merz W, Myers MG, Crotty Alexander LE, Doran N. PMID: 35382679; PMCID: PMC9214665.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Obesity alters pathology and treatment response in inflammatory disease. Nature. 2022 04; 604(7905):337-342.
Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Crotty Alexander LE, Suh JM, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee IK, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A. PMID: 35355021; PMCID: PMC9165753.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Dual use of e-cigarettes with conventional tobacco is associated with increased sleep latency in cross-sectional Study. Sci Rep. 2022 02 15; 12(1):2536.
Advani I, Gunge D, Boddu S, Mehta S, Park K, Perera S, Pham J, Nilaad S, Olay J, Ma L, Masso-Silva J, Sun X, Jain S, Malhotra A, Crotty Alexander LE. PMID: 35169234; PMCID: PMC8847556.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 02 11; 74(3):479-489.
Masso-Silva JA, Moshensky A, Lam MTY, Odish MF, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott RK, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 33988226; PMCID: PMC8241438.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Beware, vaping e-cigarettes around children is adversely impacting their lung health. Thorax. 2022 07; 77(7):638-639.
Fuentes AL, Crotty Alexander LE. PMID: 35012999.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Just When We Thought Nothing Could Be Worse Than Smoking Tobacco, Vaping e-Hookah Proves Us Wrong. Chest. 2022 01; 161(1):13-15.
Masso-Silva JA, Crotty Alexander LE. PMID: 35000699.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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A census of the lung: CellCards from LungMAP. Dev Cell. 2022 01 10; 57(1):112-145.e2.
Sun X, Perl AK, Li R, Bell SM, Sajti E, Kalinichenko VV, Kalin TV, Misra RS, Deshmukh H, Clair G, Kyle J, Crotty Alexander LE, Masso-Silva JA, Kitzmiller JA, Wikenheiser-Brokamp KA, Deutsch G, Guo M, Du Y, Morley MP, Valdez MJ, Yu HV, Jin K, Bardes EE, Zepp JA, Neithamer T, Basil MC, Zacharias WJ, Verheyden J, Young R, Bandyopadhyay G, Lin S, Ansong C, Adkins J, Salomonis N, Aronow BJ, Xu Y, Pryhuber G, Whitsett J, Morrisey EE, NHLBI LungMAP Consortium. PMID: 34936882; PMCID: PMC9202574.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Deleterious Association of Inhalant Use on Sleep Quality during the COVID-19 Pandemic. Int J Environ Res Public Health. 2021 12 15; 18(24).
Gunge D, Marganski J, Advani I, Boddu S, Chen YJE, Mehta S, Merz W, Fuentes AL, Malhotra A, Banks SJ, Crotty Alexander LE. PMID: 34948812; PMCID: PMC8703610.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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E-liquids and vaping devices: public policy regarding their effects on young people and health. Med J Aust. 2022 01 17; 216(1):23-24.
Advani IN, Perez M, Crotty Alexander LE. PMID: 34863086; PMCID: PMC8862754.
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PubMed Mentions: Fields:
Translation:
Humans
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The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 02; 149(2):488-516.e9.
Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P, PrecISE Study Team. PMID: 34848210; PMCID: PMC8821377.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Vaping and Lung Inflammation and Injury. Annu Rev Physiol. 2022 02 10; 84:611-629.
Park JA, Crotty Alexander LE, Christiani DC. PMID: 34724436; PMCID: PMC10228557.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Assessing the potential impact of age and inhalant use on sleep in adolescents. J Clin Sleep Med. 2021 11 01; 17(11):2233-2239.
Malhotra CK, Gunge D, Advani I, Boddu S, Nilaad S, Crotty Alexander LE. PMID: 34027889; PMCID: PMC8636377.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Inflammatory phenotype modulation in the respiratory tract and systemic circulation of e-cigarette users: a pilot study. Am J Physiol Lung Cell Mol Physiol. 2021 12 01; 321(6):L1134-L1146.
Sayed IM, Masso-Silva JA, Mittal A, Patel A, Lin E, Moshensky A, Shin J, Bojanowski CM, Das S, Akuthota P, Crotty Alexander LE. PMID: 34704852; PMCID: PMC8715026.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Mental Health Symptoms Among US Medical School Applicants During the COVID-19 Pandemic. Prim Care Companion CNS Disord. 2021 09 30; 23(5).
Light MP, Gunge D, LaBuzetta JN, Advani I, Crotty Alexander LE, Kamdar BB. PMID: 34592797; PMCID: PMC9011921.
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PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19. bioRxiv. 2021 Aug 24.
Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 34462742; PMCID: PMC8404884.
View in:
PubMed Mentions:
3
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Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity. Sci Adv. 2021 08; 7(34).
Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. PMID: 34407940; PMCID: PMC8373124.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19. Elife. 2021 08 13; 10.
Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar GD, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 34463615; PMCID: PMC8463074.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Vaping-induced metabolomic signatures in the circulation of mice are driven by device type, e-liquid, exposure duration and sex. ERJ Open Res. 2021 Jul; 7(3).
Moshensky A, Du M, Shin J, Advani I, Gunge D, Mathew D, Alkolla R, Du A, Javier C, Ma L, Tran A, Nguyen N, Olay J, Nilaad S, Ding J, Najhawan M, Watrous JD, Bojanowksi CM, Jain M, Christiani DC, Crotty Alexander LE. PMID: 34262972; PMCID: PMC8273396.
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PubMed Mentions:
4
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Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2. Front Physiol. 2021; 12:649604.
Masso-Silva JA, Moshensky A, Shin J, Olay J, Nilaad S, Advani I, Bojanowski CM, Crotty S, Li WT, Ongkeko WM, Singla S, Crotty Alexander LE. PMID: 34122126; PMCID: PMC8194307.
View in:
PubMed Mentions:
11
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Compositional Differences in the Oral Microbiome of E-cigarette Users. Front Microbiol. 2021; 12:599664.
Chopyk J, Bojanowski CM, Shin J, Moshensky A, Fuentes AL, Bonde SS, Chuki D, Pride DT, Crotty Alexander LE. PMID: 34135868; PMCID: PMC8200533.
View in:
PubMed Mentions:
15
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Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19. bioRxiv. 2021 May 05.
Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 33106807; PMCID: PMC7587781.
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PubMed Mentions:
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An International Virtual COVID-19 Critical Care Training Forum for Healthcare Workers. ATS Sch. 2021 Jun; 2(2):278-286.
Cypro A, McGuire WC, Rolfsen M, Jones N, Shah NG, Cribbs SK, Kaul V, Bojanowski CM, Pedraza I, Lynch L, Guzman L, Larsson E, Crotty Alexander LE. PMID: 34409421; PMCID: PMC8362763.
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PubMed Mentions:
3
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Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury. Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L821-L831.
Hepokoski M, Wang J, Li K, Li Y, Gupta P, Mai T, Moshensky A, Alotaibi M, Crotty Alexander LE, Malhotra A, Singh P. PMID: 33565357; PMCID: PMC8174821.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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E-cigarettes compromise the gut barrier and trigger inflammation. iScience. 2021 Feb 19; 24(2):102035.
Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S. PMID: 33537654; PMCID: PMC7841355.
View in:
PubMed Mentions:
31
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Cigarette Smoke and Nicotine-Containing Electronic-Cigarette Vapor Downregulate Lung WWOX Expression, Which Is Associated with Increased Severity of Murine Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2021 01; 64(1):89-99.
Zeng Z, Chen W, Moshensky A, Shakir Z, Khan R, Crotty Alexander LE, Ware LB, Aldaz CM, Jacobson JR, Dudek SM, Natarajan V, Machado RF, Singla S. PMID: 33058734; PMCID: PMC7780991.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Development of a National Academic Boot Camp to Improve Fellowship Readiness. ATS Sch. 2020 Dec 22; 2(1):49-65.
Drake MG, Shah NG, Lee M, Brady A, Connors GR, Clark BJ, Kritek PA, McCallister JW, Burkart KM, Pedraza I, Jamieson D, Ingram JL, Lynch L, Makani SS, Siegel-Gasiewski J, Larsson EM, Zemanick ET, Liptzin DR, Good R, Crotty Alexander LE. PMID: 33870323; PMCID: PMC8043273.
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PubMed Mentions:
2
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E-cigarettes and health risks: more to the flavor than just the name. Am J Physiol Lung Cell Mol Physiol. 2021 04 01; 320(4):L600-L614.
Ween MP, Moshensky A, Thredgold L, Bastian NA, Hamon R, Badiei A, Nguyen PT, Herewane K, Jersmann H, Bojanowski CM, Shin J, Reynolds PN, Crotty Alexander LE, Hodge SJ. PMID: 33295836; PMCID: PMC8424560.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Critical Care Education in a Pandemic through Tele-ICU. ATS Sch. 2020 Dec 03; 2(1):29-33.
Leverone NA, Ramnath VR, Munce D, Raphelson JR, Ma J, Akuthota P, Tomaszewski C, Sell RE, Crotty Alexander LE, Akrami KM, Malhotra A. PMID: 33870321; PMCID: PMC8043279.
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PubMed Mentions:
3
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E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. Chem Biol Interact. 2021 Jan 05; 333:109308.
Alasmari F, Crotty Alexander LE, Hammad AM, Horton A, Alhaddad H, Schiefer IT, Shin J, Moshensky A, Sari Y. PMID: 33242460; PMCID: PMC7752837.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Bleomycin-induced lung injury treated with venovenous extracorporeal membrane oxygenation (ECMO) and ultra-protective ventilator settings. BMJ Case Rep. 2020 Nov 23; 13(11).
Odish MF, McGuire WC, Thistlethwaite P, Crotty Alexander LE. PMID: 33229479; PMCID: PMC7684647.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Vaping disrupts ventilation-perfusion matching in asymptomatic users. J Appl Physiol (1985). 2021 02 01; 130(2):308-317.
Kizhakke Puliyakote AS, Elliott AR, Sá RC, Anderson KM, Crotty Alexander LE, Hopkins SR. PMID: 33180648; PMCID: PMC7948111.
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PubMed Mentions:
6 Fields:
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Vaping and e-cigarette use. Mysterious lung manifestations and an epidemic. Curr Opin Immunol. 2020 10; 66:143-150.
Casey AM, Muise ED, Crotty Alexander LE. PMID: 33186869; PMCID: PMC7755270.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Effects of 3-Month Exposure to E-Cigarette Aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice. Toxics. 2020 Oct 29; 8(4).
Alhaddad H, Wong W, Sari AT, Crotty Alexander LE, Sari Y. PMID: 33137879; PMCID: PMC7712012.
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PubMed Mentions:
7
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Vaping-related lung injury. Virchows Arch. 2021 Jan; 478(1):81-88.
Smith ML, Gotway MB, Crotty Alexander LE, Hariri LP. PMID: 33106908; PMCID: PMC7590536.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Cigarette Smoke Exposure Promotes Virulence of Pseudomonas aeruginosa and Induces Resistance to Neutrophil Killing. Infect Immun. 2020 10 19; 88(11).
Chien J, Hwang JH, Nilaad S, Masso-Silva JA, Jeong Ahn S, McEachern EK, Moshensky A, Byun MK, Crotty Alexander LE. PMID: 32868344; PMCID: PMC7573448.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Effects of e-cigarettes and vaping devices on cardiac and pulmonary physiology. J Physiol. 2020 11; 598(22):5039-5062.
Tsai M, Byun MK, Shin J, Crotty Alexander LE. PMID: 32975834; PMCID: PMC10506663.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimals
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E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report. Am J Respir Crit Care Med. 2020 09 15; 202(6):795-802.
Crotty Alexander LE, Ware LB, Calfee CS, Callahan SJ, Eissenberg T, Farver C, Goniewicz ML, Jaspers I, Kheradmand F, King TE, Meyer NJ, Mikheev VB, Shields PG, Shihadeh A, Strongin R, Tarran R. PMID: 32243764; PMCID: PMC7491408.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Response. Chest. 2020 08; 158(2):836-837.
Chapman DG, Larcombe AN, Bozier J, Chivers EK, Crotty Alexander LE, Ween MP. PMID: 32768076.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Reply: E-Cigarette, or Vaping, Product Use-associated Lung Injury: A Response to Perez and Crotty Alexander. Ann Am Thorac Soc. 2020 07; 17(7):908.
Perez MF, Crotty Alexander LE. PMID: 32320261; PMCID: PMC7328184.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Is Increased Sleep Responsible for Reductions in Myocardial Infarction During the COVID-19 Pandemic? Am J Cardiol. 2020 09 15; 131:128-130.
Advani I, Gunge D, Banks S, Mehta S, Park K, Patel M, Malhotra A, Crotty Alexander LE. PMID: 32703526; PMCID: PMC7305870.
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PubMed Mentions:
10 Fields:
Translation:
HumansCellsPHPublic Health
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Why Is Vaping Going Up in Flames? Ann Am Thorac Soc. 2020 05; 17(5):545-549.
Perez MF, Crotty Alexander LE. PMID: 31944819; PMCID: PMC7263393.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Reply to Letter to the Editor: "Comment on 'E-cigarette use increases susceptibility to bacterial infection by impairment of human neutrophil chemotaxis, phagocytosis, and NET formation'". Am J Physiol Cell Physiol. 2020 03 01; 318(3):C706.
Crotty Alexander LE, Meier A. PMID: 32150454.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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The Evolving Landscape of e-Cigarettes: A Systematic Review of Recent Evidence. Chest. 2020 05; 157(5):1362-1390.
Bozier J, Chivers EK, Chapman DG, Larcombe AN, Bastian NA, Masso-Silva JA, Byun MK, McDonald CF, Crotty Alexander LE, Ween MP. PMID: 32006591.
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PubMed Mentions:
64 Fields:
Translation:
HumansPHPublic Health
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Use of Electronic Cigarettes with Conventional Tobacco Is Associated with Decreased Sleep Quality in Women. Am J Respir Crit Care Med. 2019 12 01; 200(11):1431-1434.
Boddu SA, Bojanowski CM, Lam MT, Advani IN, Scholten EL, Sun X, Montgrain P, Malhotra A, Jain S, Alexander LEC. PMID: 31314572; PMCID: PMC6884046.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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E-cigarette use increases susceptibility to bacterial infection by impairment of human neutrophil chemotaxis, phagocytosis, and NET formation. Am J Physiol Cell Physiol. 2020 01 01; 318(1):C205-C214.
Corriden R, Moshensky A, Bojanowski CM, Meier A, Chien J, Nelson RK, Crotty Alexander LE. PMID: 31664858; PMCID: PMC6985828.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Design and Implementation of a Peer-Reviewed Medical Education Video Competition: The Best of American Thoracic Society Video Lecture Series. J Grad Med Educ. 2019 Oct; 11(5):592-596.
Seam N, Richards JB, Kritek PA, Khemasuwan D, McCallister JW, Santhosh L, Prasad B, Bhargava S, Clay AS, Crotty Alexander LE. PMID: 31636831; PMCID: PMC6795340.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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ATS Health Alert-Vaping-associated Pulmonary Illness (VAPI). Am J Respir Crit Care Med. 2019 10 01; 200(7):P15-P16.
Carlos WG, Crotty Alexander LE, Gross JE, Dela Cruz CS, Keller JM, Pasnick S, Jamil S. PMID: 31532698.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Vaping-associated Pulmonary Illness (VAPI). Am J Respir Crit Care Med. 2019 10 01; 200(7):P13-P14.
Carlos WG, Crotty Alexander LE, Gross JE, Dela Cruz CS, Keller JM, Pasnick S, Jamil S. PMID: 31532695.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Effects of Chronic Inhalation of Electronic Cigarette Vapor Containing Nicotine on Neurotransmitters in the Frontal Cortex and Striatum of C57BL/6 Mice. Front Pharmacol. 2019; 10:885.
Alasmari F, Crotty Alexander LE, Hammad AM, Bojanowski CM, Moshensky A, Sari Y. PMID: 31456684; PMCID: PMC6699083.
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PubMed Mentions:
17
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Human Eosinophils Express a Distinct Gene Expression Program in Response to IL-3 Compared with Common β-Chain Cytokines IL-5 and GM-CSF. J Immunol. 2019 07 15; 203(2):329-337.
Nelson RK, Brickner H, Panwar B, Ramírez-Suástegui C, Herrera-de la Mata S, Liu N, Diaz D, Alexander LEC, Ay F, Vijayanand P, Seumois G, Akuthota P. PMID: 31175163; PMCID: PMC6616007.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Recommendations for the Appropriate Structure, Communication, and Investigation of Tobacco Harm Reduction Claims. An Official American Thoracic Society Policy Statement. Am J Respir Crit Care Med. 2018 10 15; 198(8):e90-e105.
Leone FT, Carlsen KH, Chooljian D, Crotty Alexander LE, Detterbeck FC, Eakin MN, Evers-Casey S, Farber HJ, Folan P, Kathuria H, Latzka K, McDermott S, McGrath-Morrow S, Moazed F, Munzer A, Neptune E, Pakhale S, Sachs DPL, Samet J, Sufian B, Upson D. PMID: 30320525; PMCID: PMC6943880.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Ventilator-Induced Kidney Injury: Are Novel Biomarkers the Key to Prevention? Nephron. 2018; 140(2):90-93.
Hepokoski ML, Malhotra A, Singh P, Crotty Alexander LE. PMID: 29996132; PMCID: PMC6165693.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Otolaryngology in Critical Care. Ann Am Thorac Soc. 2018 06; 15(6):643-654.
Joshua J, Scholten E, Schaerer D, Mafee MF, Alexander TH, Crotty Alexander LE. PMID: 29565639; PMCID: PMC6207134.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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A computerized exposure system for animal models to optimize nicotine delivery into the brain through inhalation of electronic cigarette vapors or cigarette smoke. Saudi Pharm J. 2018 Jul; 26(5):622-628.
Alasmari F, Crotty Alexander LE, Drummond CA, Sari Y. PMID: 29989025; PMCID: PMC6035328.
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PubMed Mentions:
12
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Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice. Am J Physiol Regul Integr Comp Physiol. 2018 06 01; 314(6):R834-R847.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC. PMID: 29384700; PMCID: PMC6032308.
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PubMed Mentions:
101 Fields:
Translation:
HumansAnimals
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Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice. Prog Neuropsychopharmacol Biol Psychiatry. 2017 07 03; 77:1-8.
Alasmari F, Crotty Alexander LE, Nelson JA, Schiefer IT, Breen E, Drummond CA, Sari Y. PMID: 28347687; PMCID: PMC5466499.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma. Clin Immunol. 2017 03; 176:94-99.
Dewitz C, McEachern E, Shin S, Akong K, Nagle DG, Broide DH, Akuthota P, Crotty Alexander LE. PMID: 28093362.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Hypothesis: may e-cigarette smoking boost the allergic epidemic? Clin Transl Allergy. 2016; 6:40.
Bousquet J, Bachert C, Alexander LC, Leone FT. PMID: 27891215; PMCID: PMC5111212.
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PubMed Mentions:
7
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Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney. Am J Physiol Renal Physiol. 2017 04 01; 312(4):F654-F660.
Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P. PMID: 28365585; PMCID: PMC5407070.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Cigarette smoking causes epigenetic changes associated with cardiorenal fibrosis. Physiol Genomics. 2016 12 01; 48(12):950-960.
Drummond CA, Crotty Alexander LE, Haller ST, Fan X, Xie JX, Kennedy DJ, Liu J, Yan Y, Hernandez DA, Mathew DP, Cooper CJ, Shapiro JI, Tian J. PMID: 27789733; PMCID: PMC5206391.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Spontaneous Pneumothorax Complicating Chronic Hepatic Hydrothorax: Successful Treatment by Small Bore Chest Tube. J Bronchology Interv Pulmonol. 2016 Oct; 23(4):e43-e45.
Hepokoski M, Makani SS, Lerner AD, Crotty Alexander LE. PMID: 27764014.
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PubMed Mentions: Fields:
Translation:
Humans
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HIF2α-arginase axis is essential for the development of pulmonary hypertension. Proc Natl Acad Sci U S A. 2016 08 02; 113(31):8801-6.
Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. PMID: 27432976; PMCID: PMC4978263.
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PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Global state of tobacco use: summary from the American Thoracic Society International Conference 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S582-5.
Shin S, Crotty Alexander LE. PMID: 27606101; PMCID: PMC4990678.
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PubMed Mentions:
4
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Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016 06; 94(6):667-79.
Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, Das S, Moshensky A, Bapat S, Pride DT, Ongkeko WM, Crotty Alexander LE. PMID: 26804311.
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PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. Oral Oncol. 2016 Jan; 52:58-65.
Yu V, Rahimy M, Korrapati A, Xuan Y, Zou AE, Krishnan AR, Tsui T, Aguilera JA, Advani S, Crotty Alexander LE, Brumund KT, Wang-Rodriguez J, Ongkeko WM. PMID: 26547127; PMCID: PMC4891196.
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PubMed Mentions:
108 Fields:
Translation:
HumansCells
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Inflammatory Diseases of the Lung Induced by Conventional Cigarette Smoke: A Review. Chest. 2015 Nov; 148(5):1307-1322.
Crotty Alexander LE, Shin S, Hwang JH. PMID: 26135024.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Electronic cigarettes: the new face of nicotine delivery and addiction. J Thorac Dis. 2015 Aug; 7(8):E248-51.
Crotty Alexander LE, Vyas A, Schraufnagel DE, Malhotra A. PMID: 26380791; PMCID: PMC4561260.
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PubMed Mentions:
14
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The Need for More E-Cigarette Data: A Call to Action. Am J Respir Crit Care Med. 2015 Aug 01; 192(3):275-6.
Crotty Alexander L, Fuster M, Montgrain P, Malhotra A. PMID: 26230232.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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The Civil Liberty of Smoking Cigarettes. Chest. 2015 Jul; 148(1):6-8.
Crotty Alexander LE, Malhotra A. PMID: 26149548.
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PubMed Mentions:
2 Fields:
Translation:
HumansCellsPHPublic Health
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Analysis of the effects of cigarette smoke on staphylococcal virulence phenotypes. Infect Immun. 2015 Jun; 83(6):2443-52.
McEachern EK, Hwang JH, Sladewski KM, Nicatia S, Dewitz C, Mathew DP, Nizet V, Crotty Alexander LE. PMID: 25824841; PMCID: PMC4432760.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. J Mol Med (Berl). 2014 Dec; 92(12):1305-17.
Vega VL, Crotty Alexander LE, Charles W, Hwang JH, Nizet V, De Maio A. PMID: 25163764.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection. PLoS One. 2013; 8(12):e84481.
Crotty Alexander LE, Marsh BJ, Timmer AM, Lin AE, Zainabadi K, Czopik A, Guarente L, Nizet V. PMID: 24386389; PMCID: PMC3873454.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Epidermal deletion of HIF-2α stimulates wound closure. J Invest Dermatol. 2014 Mar; 134(3):801-808.
Cowburn AS, Alexander LEC, Southwood M, Nizet V, Chilvers ER, Johnson RS. PMID: 24037341; PMCID: PMC3877686.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model. Clin Immunol. 2013 Apr; 147(1):27-37.
Baek KJ, Cho JY, Rosenthal P, Alexander LEC, Nizet V, Broide DH. PMID: 23499929; PMCID: PMC3812068.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. J Mol Med (Berl). 2013 May; 91(5):637-44.
Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H, Johnson RS, Broide DH, Nizet V. PMID: 23250618; PMCID: PMC3646920.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Rescuing of deficient killing and phagocytic activities of macrophages derived from non-obese diabetic mice by treatment with geldanamycin or heat shock: potential clinical implications. Cell Stress Chaperones. 2011 Sep; 16(5):573-81.
Vega VL, Charles W, Crotty Alexander LE, Alexander LE. PMID: 21626279; PMCID: PMC3156255.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One. 2010 Jan 05; 5(1):e8557.
Cogen AL, Yamasaki K, Muto J, Sanchez KM, Crotty Alexander L, Tanios J, Lai Y, Kim JE, Nizet V, Gallo RL. PMID: 20052280; PMCID: PMC2796718.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl). 2010 Apr; 88(4):371-81.
Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. PMID: 19960175; PMCID: PMC2843839.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition. J Biol Chem. 2005 Jan 21; 280(3):1882-92.
Laugel B, Boulter JM, Lissin N, Vuidepot A, Li Y, Gostick E, Crotty LE, Douek DC, Hemelaar J, Price DA, Jakobsen BK, Sewell AK. PMID: 15531581.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors. Clin Cancer Res. 2003 Sep 15; 9(11):4247-54.
Heimberger AB, Crotty LE, Archer GE, Hess KR, Wikstrand CJ, Friedman AH, Friedman HS, Bigner DD, Sampson JH. PMID: 14519652.
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PubMed Mentions:
114 Fields:
Translation:
AnimalsCells
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Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood. 2003 Apr 01; 101(7):2711-20.
Brenchley JM, Karandikar NJ, Betts MR, Ambrozak DR, Hill BJ, Crotty LE, Casazza JP, Kuruppu J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA. PMID: 12433688.
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PubMed Mentions:
476 Fields:
Translation:
HumansCells
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Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma. Neurosurgery. 2002 Jan; 50(1):158-64; discussion 164-6.
Heimberger AB, Archer GE, Crotty LE, McLendon RE, Friedman AH, Friedman HS, Bigner DD, Sampson JH. PMID: 11844246.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system. Cancer Immunol Immunother. 2002 Feb; 50(12):639-52.
Wikstrand CJ, Cole VR, Crotty LE, Sampson JH, Bigner DD. PMID: 11862416; PMCID: PMC11034303.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCellsPHPublic Health
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Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7503-8.
Sampson JH, Crotty LE, Lee S, Archer GE, Ashley DM, Wikstrand CJ, Hale LP, Small C, Dranoff G, Friedman AH, Friedman HS, Bigner DD. PMID: 10852962; PMCID: PMC16575.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma. J Neuroimmunol. 2000 Feb 01; 103(1):16-25.
Heimberger AB, Crotty LE, Archer GE, McLendon RE, Friedman A, Dranoff G, Bigner DD, Sampson JH. PMID: 10674985.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCellsPHPublic Health