Erik Kistler

Title(s)	Professor Of Clinical, Anesthesiology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Biography

Education and Training

Massachusetts General Hospital		Critical Care - fellowship
UCSD		Anesthesiology - residency
Harbor UCLA		Surgery - internship
The George Washington School of Medicine & Health Sciences	MD	Medicine
The Scripps Research Institute		Immunology - post-doctoral fellowship
UC San Diego	PhD	Bioengineering
UC Santa Barbara	MS	Electrical Engineering
UC Santa Barbara	BS	Electrical/Computer Engineering
UC Santa Barbara	BA	Music

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Enteral administration of the protease inhibitor gabexate mesilate preserves vascular function in experimental trauma/hemorrhagic shock. Sci Rep. 2023 06 22; 13(1):10148. J D Moreira N, Dos Santos F, Li JB, Aletti F, Irigoyen MCC, Kistler EB. PMID: 37349360; PMCID: PMC10287748.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Animals
A fully integrated wearable ultrasound system to monitor deep tissues in moving subjects. Nat Biotechnol. 2024 Mar; 42(3):448-457. Lin M, Zhang Z, Gao X, Bian Y, Wu RS, Park G, Lou Z, Zhang Z, Xu X, Chen X, Kang A, Yang X, Yue W, Yin L, Wang C, Qi B, Zhou S, Hu H, Huang H, Li M, Gu Y, Mu J, Yang A, Yaghi A, Chen Y, Lei Y, Lu C, Wang R, Wang J, Xiang S, Kistler EB, Vasconcelos N, Xu S. PMID: 37217752.

View in: PubMed Mentions: 5 Fields:
Bio Biotechnology
Translation:Humans
Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis. Front Mol Biosci. 2022; 9:1051471. Dos Santos F, Li JB, Juocys N, Mazor R, Beretta L, Coufal NG, Lam MTY, Odish MF, Irigoyen MC, O'Donoghue AJ, Aletti F, Kistler EB. PMID: 36710882; PMCID: PMC9874325.

View in: PubMed Mentions:
Enteral gabexate mesilate improves volume requirements and autonomic cardiovascular function after experimental trauma/hemorrhagic shock in the absence of blood reperfusion. Am J Transl Res. 2022; 14(10):7391-7402. Dos Santos F, Li JB, Moreira NJ, Mazor R, Aletti F, Kistler EB. PMID: 36398214; PMCID: PMC9641450.

View in: PubMed Mentions: 1
Association of Serum Amylase Levels With Mortality in Critically Ill Patients With Coronavirus Disease 2019. Pancreas. 2022 08 01; 51(7):e97-e99. Kowalczyk M, Gabriel RA, Malhotra A, Kistler EB. PMID: 36395414; PMCID: PMC9722323.

View in: PubMed Mentions: Fields:
Gas Gastroenterology
Translation:Humans
Efficacy of Tranexamic Acid in Blood Versus Crystalloid-Resuscitated Trauma/Hemorrhagic Shock. J Surg Res. 2022 11; 279:89-96. Dos Santos F, Li JB, Mazor R, Aletti F, Kistler EB. PMID: 35752157.

View in: PubMed Mentions: Fields:
Gen General Surgery
Translation:Animals
Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays. Nat Biomed Eng. 2021 07; 5(7):749-758. Wang C, Qi B, Lin M, Zhang Z, Makihata M, Liu B, Zhou S, Huang YH, Hu H, Gu Y, Chen Y, Lei Y, Lee T, Chien S, Jang KI, Kistler EB, Xu S. PMID: 34272524.

View in: PubMed Mentions: 26 Fields:
Bio Biomedical Engineering
Translation:Humans
Involvement of Toll-Like Receptor 4 in Decreased Vasopressor Response Following Trauma/Hemorrhagic Shock. Crit Care Explor. 2021 Jul; 3(7):e0469. Mazor R, Dos Santos F, Li JB, Aletti F, Schmid-Schonbein G, Kistler EB. PMID: 34250499; PMCID: PMC8263324.

View in: PubMed Mentions: 3
Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin. Sci Rep. 2021 01 28; 11(1):2509. Muller CR, Courelli V, Lucas A, Williams AT, Li JB, Dos Santos F, Cuddington CT, Moses SR, Palmer AF, Kistler EB, Cabrales P. PMID: 33510204; PMCID: PMC7843604.

View in: PubMed Mentions: 13 Fields:
Sci Science
Translation:Humans Animals
Continuous enteral protease inhibition as a novel treatment for experimental trauma/hemorrhagic shock. Eur J Trauma Emerg Surg. 2022 Jun; 48(3):1579-1588. Aletti F, DeLano FA, Maffioli E, Mu H, Schmid-Schönbein GW, Tedeschi G, Kistler EB. PMID: 33483765.

View in: PubMed Mentions: 4 Fields:
Eme Emergency Medicine Tra Traumatology
Translation:Humans Animals
Resuscitation After Hemorrhagic Shock in the Microcirculation: Targeting Optimal Oxygen Delivery in the Design of Artificial Blood Substitutes. Front Med (Lausanne). 2020; 7:585638. Munoz C, Aletti F, Govender K, Cabrales P, Kistler EB. PMID: 33195342; PMCID: PMC7652927.

View in: PubMed Mentions: 2
Gut Ischemia Reperfusion Injury Induces Lung Inflammation via Mesenteric Lymph-Mediated Neutrophil Activation. Front Immunol. 2020; 11:586685. Ma Y, Zabell T, Creasy A, Yang X, Chatterjee V, Villalba N, Kistler EB, Wu MH, Yuan SY. PMID: 33042165; PMCID: PMC7517702.

View in: PubMed Mentions: 13 Fields:
All Allergy and Immunology
Translation:Animals
High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma. Molecules. 2020 Sep 06; 25(18). Maffioli E, Jiang Z, Nonnis S, Negri A, Romeo V, Lietz CB, Hook V, Ristagno G, Baselli G, Kistler EB, Aletti F, O'Donoghue AJ, Tedeschi G. PMID: 32899982; PMCID: PMC7571063.

View in: PubMed Mentions: 3 Fields:
Bio Biology
Translation:Animals Cells
A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock. Crit Care. 2019 12 19; 23(1):414. Braga D, Barcella M, Herpain A, Aletti F, Kistler EB, Bollen Pinto B, Bendjelid K, Barlassina C. PMID: 31856860; PMCID: PMC6921511.

View in: PubMed Mentions: 16 Fields:
Cri Critical Care
Translation:Humans Cells
Enteral Tranexamic Acid Decreases Proteolytic Activity in the Heart in Acute Experimental Hemorrhagic Shock. J Cardiovasc Pharmacol Ther. 2019 09; 24(5):484-493. Aletti F, Santamaria M, Chin K, Mazor R, Kistler EB. PMID: 31035788.

View in: PubMed Mentions: Fields:
Car Cardiology Pha Pharmacology Vas Vascular Diseases
Translation:Animals Cells
Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice. Sci Transl Med. 2018 08 22; 10(455). Mazor R, Friedmann-Morvinski D, Alsaigh T, Kleifeld O, Kistler EB, Rousso-Noori L, Huang C, Li JB, Verma IM, Schmid-Schönbein GW. PMID: 30135249; PMCID: PMC9678493.

View in: PubMed Mentions: 27 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Proteolysis in septic shock patients: plasma peptidomic patterns are associated with mortality. Br J Anaesth. 2018 Nov; 121(5):1065-1074. Bauzá-Martinez J, Aletti F, Pinto BB, Ribas V, Odena MA, Díaz R, Romay E, Ferrer R, Kistler EB, Tedeschi G, Schmid-Schönbein GW, Herpain A, Bendjelid K, de Oliveira E. PMID: 30336851.

View in: PubMed Mentions: 19 Fields:
Ane Anesthesiology
Translation:Humans Cells
Enteral tranexamic acid attenuates vasopressor resistance and changes in α1-adrenergic receptor expression in hemorrhagic shock. J Trauma Acute Care Surg. 2017 08; 83(2):263-270. Santamaria MH, Aletti F, Li JB, Tan A, Chang M, Leon J, Schmid-Schönbein GW, Kistler EB. PMID: 28422915; PMCID: PMC5522343.

View in: PubMed Mentions: 4 Fields:
Gen General Surgery Tra Traumatology
Translation:Animals
Preliminary profiling of blood transcriptome in a rat model of hemorrhagic shock. Exp Biol Med (Maywood). 2017 08; 242(14):1462-1470. Braga D, Barcella M, D'Avila F, Lupoli S, Tagliaferri F, Santamaria MH, DeLano FA, Baselli G, Schmid-Schönbein GW, Kistler EB, Aletti F, Barlassina C. PMID: 28661205; PMCID: PMC5544169.

View in: PubMed Mentions: 3 Fields:
Bio Biology Med Medicine (General)Phy Physiology
Translation:Animals Cells
Severity of Acute Kidney Injury in the Post-Lung Transplant Patient Is Associated With Higher Healthcare Resources and Cost. J Cardiothorac Vasc Anesth. 2017 Aug; 31(4):1361-1369. Nguyen AP, Gabriel RA, Golts E, Kistler EB, Schmidt U. PMID: 28455097.

View in: PubMed Mentions: 7 Fields:
Ane Anesthesiology Car Cardiology Pul Pulmonary Medicine
Translation:Humans
Autodigestion: Proteolytic Degradation and Multiple Organ Failure in Shock. Shock. 2016 May; 45(5):483-9. Altshuler AE, Kistler EB, Schmid-Schönbein GW. PMID: 26717111; PMCID: PMC4833612.

View in: PubMed Mentions: 10 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Humans Animals
Peptidomic Analysis of Rat Plasma: Proteolysis in Hemorrhagic Shock. Shock. 2016 May; 45(5):540-54. Aletti F, Maffioli E, Negri A, Santamaria MH, DeLano FA, Kistler EB, Schmid-Schönbein GW, Tedeschi G. PMID: 26863123; PMCID: PMC4833562.

View in: PubMed Mentions: 10 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals Cells
Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin. EuPA Open Proteom. 2016 Sep; 12:1-3. Maffioli E, Aletti F, Santagata F, Negri A, Santamaria MH, De Lano FA, Kistler EB, Schmid-Schönbein GW, Tedeschi G. PMID: 29900112; PMCID: PMC5988501.

View in: PubMed Mentions: 1
Heparin Interaction with the Primed Polymorphonuclear Leukocyte CD11b Induces Apoptosis and Prevents Cell Activation. J Immunol Res. 2015; 2015:751014. Cohen-Mazor M, Mazor R, Kristal B, Kistler EB, Ziv I, Chezar J, Sela S. PMID: 26819958; PMCID: PMC4706932.

View in: PubMed Mentions: 3 Fields:
All Allergy and Immunology
Translation:Humans Cells
In vivo analysis of intestinal permeability following hemorrhagic shock. World J Crit Care Med. 2015 Nov 04; 4(4):287-95. Alsaigh T, Chang M, Richter M, Mazor R, Kistler EB. PMID: 26557479; PMCID: PMC4631874.

View in: PubMed Mentions: 8
Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies. J Funct Biomater. 2014 Oct 27; 5(4):232-45. Tsai AG, Salazar Vázquez BY, Cabrales P, Kistler EB, Tartakovsky DM, Subramaniam S, Acharya SA, Intaglietta M. PMID: 25350267; PMCID: PMC4285404.

View in: PubMed Mentions: 2
Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells. J Biol Chem. 2013 Jan 04; 288(1):598-607. Mazor R, Alsaigh T, Shaked H, Altshuler AE, Pocock ES, Kistler EB, Karin M, Schmid-Schönbein GW. PMID: 23155052; PMCID: PMC3537058.

View in: PubMed Mentions: 36 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Impaired small-bowel barrier integrity in the presence of lumenal pancreatic digestive enzymes leads to circulatory shock. Shock. 2012 Aug; 38(3):262-7. Kistler EB, Alsaigh T, Chang M, Schmid-Schönbein GW. PMID: 22576000; PMCID: PMC3422435.

View in: PubMed Mentions: 17 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals
Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine. PLoS One. 2012; 7(6):e40087. Chang M, Alsaigh T, Kistler EB, Schmid-Schönbein GW. PMID: 22768227; PMCID: PMC3387149.

View in: PubMed Mentions: 46 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Disruption of the mucosal barrier during gut ischemia allows entry of digestive enzymes into the intestinal wall. Shock. 2012 Mar; 37(3):297-305. Chang M, Kistler EB, Schmid-Schönbein GW. PMID: 22089198; PMCID: PMC3288241.

View in: PubMed Mentions: 34 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals
An elementary analysis of physiologic shock and multi-organ failure: the autodigestion hypothesis. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:3114-5. Schmid-Schonbein GW, DeLano FA, Penn AH, Kistler E. PMID: 23366584.

View in: PubMed Mentions: 4 Fields:
Bio Biomedical Engineering
Translation:Humans
The Autodigestion Hypothesis in Shock and Multi-Organ Failure: Degrading Protease Activity. Bol Soc Port Hemorreol Microcirc. 2011 Jul; 26(3):6-15. Schmid-Schönbein GW, Penn A, Kistler E. PMID: 25284955; PMCID: PMC4180238.

View in: PubMed Mentions: 1
Limitations of volumetric indices obtained by trans-thoracic thermodilution. Minerva Anestesiol. 2010 Nov; 76(11):945-9. Bigatello LM, Kistler EB, Noto A. PMID: 21102390.

View in: PubMed Mentions: 6 Fields:
Ane Anesthesiology
Translation:Humans
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock. Shock. 2002 Mar; 17(3):205-9. Mitsuoka H, Kistler EB, Schmid-Schönbein GW. PMID: 11900339.

View in: PubMed Mentions: 19 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Humans Animals Cells
Pancreatic enzymes and microvascular cell activation in multiorgan failure. Microcirculation. 2001 Feb; 8(1):5-14. Schmid-Schönbein GW, Hugli TE, Kistler EB, Sofianos A, Mitsuoka H. PMID: 11296853.

View in: PubMed Mentions: 3 Fields:
Vas Vascular Diseases
Translation:Humans Animals
Plasma activation during splanchnic arterial occlusion shock. Shock. 2000 Jul; 14(1):30-4. Kistler EB, Lefer AM, Hugli TE, Schmid-Schönbein GW. PMID: 10909890.

View in: PubMed Mentions: 13 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals Cells
The pancreas as a source of cardiovascular cell activating factors. Microcirculation. 2000 Jun; 7(3):183-92. Kistler EB, Hugli TE, Schmid-Schönbein GW. PMID: 10901497.

View in: PubMed Mentions: 18 Fields:
Vas Vascular Diseases
Translation:Animals Cells
Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1772-7. Mitsuoka H, Kistler EB, Schmid-Schonbein GW. PMID: 10677533; PMCID: PMC26511.

View in: PubMed Mentions: 35 Fields:
Sci Science
Translation:Animals Cells