Prabhleen Singh

Title(s)	Professor In Residence, Medicine
School	Vc-health Sciences-schools
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Research

Research Activities and Funding

Glomerular and Tubular Function in the Diabetic Kidney
NIH-NIDDK R01DK112042Apr 1, 2023 - Mar 31, 2027
Role: Co-Investigator

Glomerular and Tubular Function in the Recovering Kidney
NIH-NIDDK R01DK132690Jan 1, 2023 - Dec 31, 2027
Role: Co-Investigator

Renal Oxygenation and Mitochondrial Function in AKI
NIH R01DK107852Aug 18, 2016 - Mar 31, 2021
Role: Principal Investigator

“Role of AMP-Kinase in renal oxygenation in diabetic kidney”
American Diabetes Association 4-15-CKD-70Jul 1, 2015 - Jun 30, 2018
Role: Principal Investigator

Renal Oxygenation and Hemodynamics in Sepsis Associated Acute Kidney Injury
NIH R03DK101841Jul 1, 2015 - Jun 30, 2018
Role: Principal Investigator

Renal Oxygenation in the Pathophysiology of Kidney Disease
NIH I01BX002175Jan 1, 2015 - Mar 31, 2025
Role: Principal Investigator

Pathophysiology of Early Chronic Kidney Disease: Response to Ischemia-Reperfusion
NIH K08DK084305Jul 1, 2010 - Jun 30, 2016
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Energy Metabolism Dysregulation in Chronic Kidney Disease. Kidney360. 2023 08 01; 4(8):1080-1094. Li Y, Gu W, Hepokoski M, Pham H, Tham R, Kim YC, Simonson TS, Singh P. PMID: 37222594; PMCID: PMC10476685.

View in: PubMed Mentions: 1 Fields:
Nep Nephrology
Translation:Humans
Reprogramming of Energy Metabolism in Kidney Disease. Nephron. 2023; 147(1):61-64. Singh P. PMID: 36063803; PMCID: PMC9928604.

View in: PubMed Mentions: 4 Fields:
Nep Nephrology
Translation:Humans
Mitochondria as mediators of systemic inflammation and organ cross talk in acute kidney injury. Am J Physiol Renal Physiol. 2022 06 01; 322(6):F589-F596. Hepokoski M, Singh P. PMID: 35379000; PMCID: PMC9054254.

View in: PubMed Mentions: 6 Fields:
Nep Nephrology Phy Physiology
Translation:Humans Cells
Targeting Mitochondria and Metabolism in Acute Kidney Injury. J Clin Med. 2021 Sep 03; 10(17). Li Y, Hepokoski M, Gu W, Simonson T, Singh P. PMID: 34501442; PMCID: PMC8432487.

View in: PubMed Mentions: 10
Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury. Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L821-L831. Hepokoski M, Wang J, Li K, Li Y, Gupta P, Mai T, Moshensky A, Alotaibi M, Crotty Alexander LE, Malhotra A, Singh P. PMID: 33565357; PMCID: PMC8174821.

View in: PubMed Mentions: 21 Fields:
Cel Cell Biology Mol Molecular Biology Phy Physiology Pul Pulmonary Medicine
Translation:Animals Cells
Evolution of altered tubular metabolism and mitochondrial function in sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020 08 01; 319(2):F229-F244. Li Y, Nourbakhsh N, Pham H, Tham R, Zuckerman JE, Singh P. PMID: 32538150; PMCID: PMC7473900.

View in: PubMed Mentions: 20 Fields:
Nep Nephrology Phy Physiology
Translation:Animals Cells
Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease. JCI Insight. 2020 04 09; 5(7). Bush KT, Singh P, Nigam SK. PMID: 32271169; PMCID: PMC7205256.

View in: PubMed Mentions: 29 Fields:
Med Medicine (General)
Translation:Animals
Ventilator-Induced Kidney Injury: Are Novel Biomarkers the Key to Prevention? Nephron. 2018; 140(2):90-93. Hepokoski ML, Malhotra A, Singh P, Crotty Alexander LE. PMID: 29996132; PMCID: PMC6165693.

View in: PubMed Mentions: 13 Fields:
Nep Nephrology
Translation:Humans
Mice overexpressing chromogranin A display hypergranulogenic adrenal glands with attenuated ATP levels contributing to the hypertensive phenotype. J Hypertens. 2018 05; 36(5):1115-1128. Mir SA, Li Y, Story JD, Bal S, Awdishu L, Street AA, Mehta RL, Singh P, Vaingankar SM. PMID: 29389743; PMCID: PMC6462411.

View in: PubMed Mentions: 1 Fields:
Vas Vascular Diseases
Translation:Animals Cells
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice. Am J Physiol Regul Integr Comp Physiol. 2018 06 01; 314(6):R834-R847. Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC. PMID: 29384700; PMCID: PMC6032308.

View in: PubMed Mentions: 96 Fields:
Phy Physiology
Translation:Humans Animals
Renal hemodynamic effects of glucagon-like peptide-1 agonist are mediated by nitric oxide but not prostaglandin. Am J Physiol Renal Physiol. 2017 Oct 01; 313(4):F854-F858. Thomson SC, Kashkouli A, Liu ZZ, Singh P. PMID: 28724607; PMCID: PMC5668591.

View in: PubMed Mentions: 5 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Renal Oxygenation in the Pathophysiology of Chronic Kidney Disease. Front Physiol. 2017; 8:385. Liu ZZ, Bullen A, Li Y, Singh P. PMID: 28701959; PMCID: PMC5487476.

View in: PubMed Mentions: 13
Renal Oxygenation and Hemodynamics in Kidney Injury. Nephron. 2017; 137(4):260-263. Bullen A, Liu ZZ, Hepokoski M, Li Y, Singh P. PMID: 28614837; PMCID: PMC5732093.

View in: PubMed Mentions: 18 Fields:
Nep Nephrology
Translation:Humans
Hypoxia-inducible factor-1α activation improves renal oxygenation and mitochondrial function in early chronic kidney disease. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F282-F290. Thomas JL, Pham H, Li Y, Hall E, Perkins GA, Ali SS, Patel HH, Singh P. PMID: 28331062; PMCID: PMC5582905.

View in: PubMed Mentions: 18 Fields:
Nep Nephrology Phy Physiology
Translation:Animals Cells
Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney. Am J Physiol Renal Physiol. 2017 04 01; 312(4):F654-F660. Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P. PMID: 28365585; PMCID: PMC5407070.

View in: PubMed Mentions: 29 Fields:
Nep Nephrology Phy Physiology
Translation:Animals Cells
Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease. Am J Physiol Renal Physiol. 2015 Sep 01; 309(5):F414-28. Li H, Satriano J, Thomas JL, Miyamoto S, Sharma K, Pastor-Soler NM, Hallows KR, Singh P. PMID: 26136559; PMCID: PMC4556888.

View in: PubMed Mentions: 33 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Role of renal oxygenation and mitochondrial function in the pathophysiology of acute kidney injury. Nephron Clin Pract. 2014; 127(1-4):149-52. Nourbakhsh N, Singh P. PMID: 25343840; PMCID: PMC5540439.

View in: PubMed Mentions: 24 Fields:
Nep Nephrology
Translation:Humans Animals Cells
Glomerular and tubular function in the diabetic kidney. Adv Chronic Kidney Dis. 2014 May; 21(3):297-303. Blantz RC, Singh P. PMID: 24780458.

View in: PubMed Mentions: 15 Fields:
Nep Nephrology
Translation:Humans
Salt sensitivity of tubuloglomerular feedback in the early remnant kidney. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F172-80. Singh P, Thomson SC. PMID: 24259514; PMCID: PMC3920016.

View in: PubMed Mentions: 5 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease. Clin Exp Pharmacol Physiol. 2013 Feb; 40(2):138-47. Singh P, Ricksten SE, Bragadottir G, Redfors B, Nordquist L. PMID: 23360244; PMCID: PMC3710120.

View in: PubMed Mentions: 62 Fields:
Pha Pharmacology Phy Physiology
Translation:Humans Animals
Podocytes express IL-6 and lipocalin 2/ neutrophil gelatinase-associated lipocalin in lipopolysaccharide-induced acute glomerular injury. Nephron Exp Nephrol. 2012; 121(3-4):e86-96. Lee SJ, Borsting E, Declèves AE, Singh P, Cunard R. PMID: 23234871; PMCID: PMC4012854.

View in: PubMed Mentions: 15 Fields:
Nep Nephrology
Translation:Animals Cells
Glucagon-like peptide-1 receptor stimulation increases GFR and suppresses proximal reabsorption in the rat. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F137-44. Thomson SC, Kashkouli A, Singh P. PMID: 23019232; PMCID: PMC3543628.

View in: PubMed Mentions: 33 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A(1) receptors. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F405-11. Blantz RC, Singh P, Deng A, Thomson SC, Vallon V. PMID: 22622464; PMCID: PMC3433865.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Aberrant tubuloglomerular feedback and HIF-1α confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 2012 Mar; 23(3):483-93. Singh P, Blantz RC, Rosenberger C, Gabbai FB, Schoeb TR, Thomson SC. PMID: 22266667; PMCID: PMC3294306.

View in: PubMed Mentions: 19 Fields:
Nep Nephrology
Translation:Animals Cells
Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 2012 Jan 01; 302(1):R75-83. Thomson SC, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. PMID: 21940401; PMCID: PMC3349378.

View in: PubMed Mentions: 131 Fields:
Phy Physiology
Translation:Animals
Analysis of the prerenal contributions to acute kidney injury. Contrib Nephrol. 2011; 174:4-11. Blantz RC, Singh P. PMID: 21921604.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology
Translation:Humans Cells
The role of tubuloglomerular feedback in the pathogenesis of acute kidney injury. Contrib Nephrol. 2011; 174:12-21. Singh P, Okusa MD. PMID: 21921605.

View in: PubMed Mentions: 25 Fields:
Nep Nephrology
Translation:Humans Animals
Renal protection in chronic kidney disease: hypoxia-inducible factor activation vs. angiotensin II blockade. Am J Physiol Renal Physiol. 2010 Dec; 299(6):F1365-73. Deng A, Arndt MA, Satriano J, Singh P, Rieg T, Thomson S, Tang T, Blantz RC. PMID: 20881034; PMCID: PMC3006314.

View in: PubMed Mentions: 40 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Chronic kidney disease: an inherent risk factor for acute kidney injury? Clin J Am Soc Nephrol. 2010 Sep; 5(9):1690-5. Singh P, Rifkin DE, Blantz RC. PMID: 20688882.

View in: PubMed Mentions: 53 Fields:
Nep Nephrology
Translation:Humans Animals
Renal homeostasis and tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 2010 Jan; 19(1):59-64. Singh P, Thomson SC. PMID: 19864948.

View in: PubMed Mentions: 13 Fields:
Nep Nephrology Vas Vascular Diseases
Translation:Humans Animals
Unexpected effect of angiotensin AT1 receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy. Am J Physiol Renal Physiol. 2009 May; 296(5):F1158-65. Singh P, Deng A, Blantz RC, Thomson SC. PMID: 19211684; PMCID: PMC2681370.

View in: PubMed Mentions: 16 Fields:
Nep Nephrology Phy Physiology
Translation:Animals
Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney Int. 2009 Jan; 75(2):197-204. Deng A, Tang T, Singh P, Wang C, Satriano J, Thomson SC, Blantz RC. PMID: 18818681; PMCID: PMC3151651.

View in: PubMed Mentions: 28 Fields:
Nep Nephrology
Translation:Animals
L-arginine-induced glomerular hyperfiltration response: the roles of insulin and ANG II. Am J Physiol Regul Integr Comp Physiol. 2008 May; 294(5):R1744-51. Ruiz M, Singh P, Thomson SC, Munger K, Blantz RC, Gabbai FB. PMID: 18353876.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Animals
The balance of angiotensin II and nitric oxide in kidney diseases. Curr Opin Nephrol Hypertens. 2008 Jan; 17(1):51-6. Singh P, Deng A, Weir MR, Blantz RC. PMID: 18090670.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology Vas Vascular Diseases
Translation:Humans Animals
Clinically immature arteriovenous hemodialysis fistulas: effect of US on salvage. Radiology. 2008 Jan; 246(1):299-305. Singh P, Robbin ML, Lockhart ME, Allon M. PMID: 17991787.

View in: PubMed Mentions: 26 Fields:
Rad Radiology
Translation:Humans