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    Dan Zhou

    TitleAssociate Project Scientist
    SchoolUniversity of California, San Diego
    DepartmentPediatrics
    Address9500 Gilman Drive #0735
    CA La Jolla 92093
    Phone858-822-6889
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Azad P, Zhao HW, Cabrales PJ, Ronen R, Zhou D, Poulsen O, Appenzeller O, Hsiao YH, Bafna V, Haddad GG. Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. J Exp Med. 2016 Nov 14; 213(12):2729-2744. PMID: 27821551.
        View in: PubMed
      2. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. PMID: 26240367.
        View in: PubMed
      3. Ronen R, Zhou D, Bafna V, Haddad GG. The genetic basis of chronic mountain sickness. Physiology (Bethesda). 2014 Nov; 29(6):403-12. PMID: 25362634.
        View in: PubMed
      4. Gersten M, Zhou D, Azad P, Haddad GG, Subramaniam S. Wnt Pathway Activation Increases Hypoxia Tolerance during Development. PLoS One. 2014; 9(8):e103292. PMID: 25093834.
        View in: PubMed
      5. Hartley I, Elkhoury FF, Heon Shin J, Xie B, Gu X, Gao Y, Zhou D, Haddad GG. Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures. PLoS One. 2013; 8(10):e77859. PMID: 24205000.
        View in: PubMed
      6. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 5; 93(3):452-62. PMID: 23954164.
        View in: PubMed
      7. Xie L, Ng C, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad GG, Bourne PE, Xie L. Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia. BMC Genomics. 2013; 14 Suppl 3:S9. PMID: 23819581.
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      8. Azad P, Zhou D, Zarndt R, Haddad GG. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. G3 (Bethesda). 2012 Oct; 2(10):1169-78. PMID: 23050227.
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      9. Perkins G, Hsiao YH, Yin S, Tjong J, Tran MT, Lau J, Xue J, Liu S, Ellisman MH, Zhou D. Ultrastructural modifications in the mitochondria of hypoxia-adapted Drosophila melanogaster. PLoS One. 2012; 7(9):e45344. PMID: 23028948.
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      10. Ali SS, Hsiao M, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. PLoS One. 2012; 7(5):e36801. PMID: 22574227.
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      11. Udpa N, Zhou D, Haddad GG, Bafna V. Tests of selection in pooled case-control data: an empirical study. Front Genet. 2011; 2:83. PMID: 22303377.
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      12. Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad GG. Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro. Am J Physiol Regul Integr Comp Physiol. 2011 Sep; 301(3):R727-45. PMID: 21677276.
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      13. Zhou D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer KA, Posakony JW, Subramaniam S, Bafna V, Haddad GG. Experimental selection of hypoxia-tolerant Drosophila melanogaster. Proc Natl Acad Sci U S A. 2011 Feb 8; 108(6):2349-54. PMID: 21262834.
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      14. Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad GG. Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. J Neurol Res. 2011; 1(5). PMID: 24348887.
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      15. Zhao HW, Zhou D, Haddad GG. Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. J Biol Chem. 2011 Feb 25; 286(8):6211-8. PMID: 21148307.
        View in: PubMed
      16. Zhao HW, Zhou D, Nizet V, Haddad GG. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010; 5(7):e11701. PMID: 20668515.
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      17. Xue J, Mraiche F, Zhou D, Karmazyn M, Oka T, Fliegel L, Haddad GG. Elevated myocardial Na+/H+ exchanger isoform 1 activity elicits gene expression that leads to cardiac hypertrophy. Physiol Genomics. 2010 Aug; 42(3):374-83. PMID: 20460605.
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      18. Zhou D, Visk DW, Haddad GG. Drosophila, a golden bug, for the dissection of the genetic basis of tolerance and susceptibility to hypoxia. Pediatr Res. 2009 Sep; 66(3):239-47. PMID: 19542900.
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      19. Azad P, Zhou D, Russo E, Haddad GG. Distinct mechanisms underlying tolerance to intermittent and constant hypoxia in Drosophila melanogaster. PLoS One. 2009; 4(4):e5371. PMID: 19401761.
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      20. Yao H, Felfly H, Wang J, Zhou D, Haddad GG. DIDS protects against neuronal injury by blocking Toll-like receptor 2 activated-mechanisms. J Neurochem. 2009 Feb; 108(3):835-46. PMID: 19077053.
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      21. Zhou D, Xue J, Lai JC, Schork NJ, White KP, Haddad GG. Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet. 2008 Oct; 4(10):e1000221. PMID: 18927626.
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      22. Zhou D, Wang J, Zapala MA, Xue J, Schork NJ, Haddad GG. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiol Genomics. 2008 Feb 19; 32(3):370-9. PMID: 18056785.
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      23. Sun X, Yao H, Zhou D, Gu X, Haddad GG. Modulation of hSlo BK current inactivation by fatty acid esters of CoA. J Neurochem. 2008 Mar; 104(5):1394-403. PMID: 18005338.
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      24. Xue J, Zhou D, Yao H, Haddad GG. Role of transporters and ion channels in neuronal injury under hypoxia. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R451-7. PMID: 17977915.
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      25. Zhou D, Xue J, Chen J, Morcillo P, Lambert JD, White KP, Haddad GG. Experimental selection for Drosophila survival in extremely low O(2) environment. PLoS One. 2007; 2(5):e490. PMID: 17534440.
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      26. Gu XQ, Siemen D, Parvez S, Cheng Y, Xue J, Zhou D, Sun X, Jonas EA, Haddad GG. Hypoxia increases BK channel activity in the inner mitochondrial membrane. Biochem Biophys Res Commun. 2007 Jun 22; 358(1):311-6. PMID: 17481584.
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      27. Xue J, Zhou D, Yao H, Gavrialov O, McConnell MJ, Gelb BD, Haddad GG. Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2406-16. PMID: 17289818.
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      28. Li G, Zhou D, Vicencio AG, Ryu J, Xue J, Kanaan A, Gavrialov O, Haddad GG. Effect of carbon dioxide on neonatal mouse lung: a genomic approach. J Appl Physiol (1985). 2006 Dec; 101(6):1556-64. PMID: 16888043.
        View in: PubMed
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