Alex Clark

Title(s)Assistant Project Scientist, Medicine
SchoolVc-health Sciences-schools
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs. Antiviral Res. 2023 11; 219:105718. McMillan RE, Lo MK, Zhang XQ, Beadle JR, Valiaeva N, Garretson AF, Clark AE, Freshman JE, Murphy J, Montgomery JM, Spiropoulou CF, Schooley RT, Hostetler KY, Carlin AF. PMID: 37758067; PMCID: PMC10790242.
      View in: PubMed   Mentions:    Fields:    
    2. Validating Tools to Detect and Inactivate Monkeypox Virus in Human Milk. Breastfeed Med. 2023 10; 18(10):785-789. Clark AE, Furst A, Sejane K, Stellwagen L, Proost M, Pride D, Smith DM, Carlin AF, Bode L. PMID: 37733262; PMCID: PMC10616931.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. 1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity. J Med Chem. 2023 04 27; 66(8):5802-5819. Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. PMID: 37040439; PMCID: PMC10108740.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment. Open Forum Infect Dis. 2023 Apr; 10(4):ofad154. Carlin AF, Clark AE, Garretson AF, Bray W, Porrachia M, Santos AT, Rana TM, Chaillon A, Smith DM. PMID: 37096144; PMCID: PMC10122487.
      View in: PubMed   Mentions: 1  
    5. Identification of global inhibitors of cellular glycosylation. Nat Commun. 2023 02 20; 14(1):948. Sørensen DM, Büll C, Madsen TD, Lira-Navarrete E, Clausen TM, Clark AE, Garretson AF, Karlsson R, Pijnenborg JFA, Yin X, Miller RL, Chanda SK, Boltje TJ, Schjoldager KT, Vakhrushev SY, Halim A, Esko JD, Carlin AF, Hurtado-Guerrero R, Weigert R, Clausen H, Narimatsu Y. PMID: 36804936; PMCID: PMC9941569.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    6. Protease-Responsive Potential-Tunable AIEgens for Cell Selective Imaging of TMPRSS2 and Accurate Inhibitor Screening. Anal Chem. 2023 02 21; 95(7):3789-3798. Cheng Y, Clark AE, Yim W, Borum RM, Chang YC, Jin Z, He T, Carlin AF, Jokerst JV. PMID: 36753444; PMCID: PMC10614162.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment. Clin Infect Dis. 2023 02 08; 76(3):e530-e532. Carlin AF, Clark AE, Chaillon A, Garretson AF, Bray W, Porrachia M, Santos AT, Rana TM, Smith DM. PMID: 35723411; PMCID: PMC9278181.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    8. The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense. bioRxiv. 2023 Jan 27. Leibel SL, McVicar RN, Murad R, Kwong EM, Clark AE, Alvarado A, Grimmig BA, Nuryyev R, Young RE, Lee JC, Peng W, Zhu YP, Griffis E, Nowell CJ, Liu K, James B, Alarcon S, Malhotra A, Gearing LJ, Hertzog PJ, Galapate CM, Galenkamp KMO, Commisso C, Smith DM, Sun X, Carlin AF, Croker BA, Snyder EY. PMID: 36747824; PMCID: PMC9900938.
      View in: PubMed   Mentions:
    9. PCIF1-mediated deposition of 5'-cap N6,2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023 Jan 31; 120(5):e2210361120. Wang L, Wang S, Wu L, Li W, Bray W, Clark AE, Gonzalez GM, Wang Y, Carlin AF, Rana TM. PMID: 36689652; PMCID: PMC9945940.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    10. In Vitro Diagnostic Assay to Detect SARS-CoV-2-Neutralizing Antibody in Patient Sera Using Engineered ACE-2 Mini-Protein. Viruses. 2022 12 18; 14(12). Pereira de Jesus BA, Gomes AA, Clark AE, Rodrigues TA, Ledgerwood-Lee M, Van Zant W, Brickner H, Wang M, Blum DL, Cassera MB, Carlin AF, Aronoff-Spencer ES, da Silva GF, Magalhães MLB, Ray P. PMID: 36560827; PMCID: PMC9780992.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika. J Chem Inf Model. 2022 12 26; 62(24):6825-6843. Mottin M, de Paula Sousa BK, de Moraes Roso Mesquita NC, de Oliveira KIZ, Noske GD, Sartori GR, de Oliveira Albuquerque A, Urbina F, Puhl AC, Moreira-Filho JT, Souza GE, Guido RVC, Muratov E, Neves BJ, Martins da Silva JH, Clark AE, Siqueira-Neto JL, Perryman AL, Oliva G, Ekins S, Andrade CH. PMID: 36239304; PMCID: PMC9923514.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus. Nat Commun. 2022 09 12; 13(1):5341. Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF. PMID: 36097162; PMCID: PMC9465152.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. A Self-Immolative Fluorescent Probe for Selective Detection of SARS-CoV-2 Main Protease. Anal Chem. 2022 08 30; 94(34):11728-11733. Xu M, Zhou J, Cheng Y, Jin Z, Clark AE, He T, Yim W, Li Y, Chang YC, Wu Z, Fajtová P, O'Donoghue AJ, Carlin AF, Todd MD, Jokerst JV. PMID: 35973073; PMCID: PMC9396966.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies. Commun Biol. 2022 08 05; 5(1):789. Li R, Mor M, Ma B, Clark AE, Alter J, Werbner M, Lee JC, Leibel SL, Carlin AF, Dessau M, Gal-Tanamy M, Croker BA, Xiang Y, Freund NT. PMID: 35931732; PMCID: PMC9355996.
      View in: PubMed   Mentions: Translation:HumansCells
    15. Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells. ACS Nano. 2022 08 23; 16(8):12305-12317. Cheng Y, Clark AE, Zhou J, He T, Li Y, Borum RM, Creyer MN, Xu M, Jin Z, Zhou J, Yim W, Wu Z, Fajtová P, O'Donoghue AJ, Carlin AF, Jokerst JV. PMID: 35878004; PMCID: PMC9344892.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Structure-selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern. PLoS Pathog. 2022 07; 18(7):e1010686. Almanza G, Clark AE, Kouznetsova V, Olmedillas E, Castro A, Tsigelny IF, Wu Y, Gao GF, Leibel SL, Bray W, Ollmann Saphire E, Carlin AF, Zanetti M. PMID: 35862442; PMCID: PMC9302722.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    17. Virologic and Immunologic Characterization of COVID-19 Recrudescence after Nirmatrelvir/Ritonavir Treatment. Res Sq. 2022 May 18. Carlin AF, Clark AE, Chaillon A, Garretson AF, Bray W, Porrachi M, Santos AT, Smith DM. PMID: 35611335; PMCID: PMC9128786.
      View in: PubMed   Mentions:
    18. Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions. Res Sq. 2022 Mar 17. Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Croker BA, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Clark AE, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. PMID: 35313591; PMCID: PMC8936114.
      View in: PubMed   Mentions:
    19. A Dual-Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain-like Proteases of SARS-CoV-2-Infected Cells for Accurate Detection and Rapid Inhibitor Screening. Angew Chem Int Ed Engl. 2022 02 21; 61(9):e202113617. Cheng Y, Borum RM, Clark AE, Jin Z, Moore C, Fajtová P, O'Donoghue AJ, Carlin AF, Jokerst JV. PMID: 34889013; PMCID: PMC8854376.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    20. Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma. Cancer Res. 2022 02 01; 82(3):377-390. Sen A, Prager BC, Zhong C, Park D, Zhu Z, Gimple RC, Wu Q, Bernatchez JA, Beck S, Clark AE, Siqueira-Neto JL, Rich JN, McVicker G. PMID: 34903607; PMCID: PMC9122831.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    21. Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring Programs. mSystems. 2021 Dec 21; 6(6):e0113621. Salido RA, Cantú VJ, Clark AE, Leibel SL, Foroughishafiei A, Saha A, Hakim A, Nouri A, Lastrella AL, Castro-Martínez A, Plascencia A, Kapadia BK, Xia B, Ruiz CA, Marotz CA, Maunder D, Lawrence ES, Smoot EW, Eisner E, Crescini ES, Kohn L, Franco Vargas L, Chacón M, Betty M, Machnicki M, Wu MY, Baer NA, Belda-Ferre P, De Hoff P, Seaver P, Ostrander RT, Tsai R, Sathe S, Aigner S, Morgan SC, Ngo TT, Barber T, Cheung W, Carlin AF, Yeo GW, Laurent LC, Fielding-Miller R, Knight R. PMID: 34726486; PMCID: PMC8562474.
      View in: PubMed   Mentions: 10     Fields:    
    22. Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus. ACS Infect Dis. 2021 11 12; 7(11):3096-3110. Ortega-Rivera OA, Shukla S, Shin MD, Chen A, Beiss V, Moreno-Gonzalez MA, Zheng Y, Clark AE, Carlin AF, Pokorski JK, Steinmetz NF. PMID: 34672530.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    23. Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 02 24; 65(4):2866-2879. Huff S, Kummetha IR, Tiwari SK, Huante MB, Clark AE, Wang S, Bray W, Smith D, Carlin AF, Endsley M, Rana TM. PMID: 34570513; PMCID: PMC8491550.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    24. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity. Sci Adv. 2021 08; 7(34). Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. PMID: 34407940; PMCID: PMC8373124.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    25. Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0115521. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 34310217; PMCID: PMC8448143.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    26. Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence. bioRxiv. 2021 Jul 19. Salido RA, Cantú VJ, Clark AE, Leibel SL, Foroughishafiei A, Saha A, Hakim A, Nouri A, Lastrella AL, Castro-Martínez A, Plascencia A, Kapadia B, Xia B, Ruiz C, Marotz CA, Maunder D, Lawrence ES, Smoot EW, Eisner E, Crescini ES, Kohn L, Vargas LF, Chacón M, Betty M, Machnicki M, Wu MY, Baer NA, Belda-Ferre P, Hoff P, Seaver P, Ostrander RT, Tsai R, Sathe S, Aigner S, Morgan SC, Ngo TT, Barber T, Cheung W, Carlin AF, Yeo GW, Laurent LC, Fielding-Miller R, Knight R. PMID: 34312621; PMCID: PMC8312891.
      View in: PubMed   Mentions:
    27. A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology. Nat Med. 2021 09; 27(9):1600-1606. Wang L, Sievert D, Clark AE, Lee S, Federman H, Gastfriend BD, Shusta EV, Palecek SP, Carlin AF, Gleeson JG. PMID: 34244682; PMCID: PMC8601037.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    28. Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs. bioRxiv. 2021 Jun 07. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 32869033; PMCID: PMC7457622.
      View in: PubMed   Mentions: 1  
    29. Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. PLoS Pathog. 2021 05; 17(5):e1009519. Park SH, Siddiqi H, Castro DV, De Angelis AA, Oom AL, Stoneham CA, Lewinski MK, Clark AE, Croker BA, Carlin AF, Guatelli J, Opella SJ. PMID: 34003853; PMCID: PMC8184013.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    30. A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS Chem Biol. 2021 04 16; 16(4):642-650. Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Kocurek KI, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Yoon MC, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Hook V, Frueh F, Hurst BL, Wang H, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. PMID: 33787221.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    31. The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26. Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697; PMCID: PMC8010724.
      View in: PubMed   Mentions: 2  
    32. A Human 3D neural assembloid model for SARS-CoV-2 infection. Res Sq. 2021 Feb 12. Wang L, Sievert D, Gleeson J, Clark AE, Carlin AF, Federman H, Gastfriend BD, Shusta E, Palecek SP. PMID: 33594354; PMCID: PMC7885926.
      View in: PubMed   Mentions:
    33. Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors. PLoS Pathog. 2021 02; 17(2):e1009165. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Lee JC, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Ben-Shalom N, Navon M, Rafael D, Sharim H, Kiner E, Griffis ER, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dessau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33571304; PMCID: PMC7877634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    34. A Human 3D neural assembloid model for SARS-CoV-2 infection. bioRxiv. 2021 Feb 09. Wang L, Sievert D, Clark AE, Federman H, Gastfriend BD, Shusta E, Palecek SP, Carlin AF, Gleeson J. PMID: 33594369; PMCID: PMC7885921.
      View in: PubMed   Mentions:
    35. Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose. J Virol. 2021 03 01; 95(5). Clark AE, Zhu Z, Krach F, Rich JN, Yeo GW, Spector DH. PMID: 33328307; PMCID: PMC8092816.
      View in: PubMed   Mentions: 3     Fields:    
    36. A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells. bioRxiv. 2020 Oct 30. Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Frueh F, Hurst BL, Wang H, Kocurek KI, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. PMID: 33140046; PMCID: PMC7605553.
      View in: PubMed   Mentions: 1  
    37. Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors. bioRxiv. 2020 Oct 06. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Shalom NB, Navon M, Rafael D, Sharim H, Kiner E, Griffis E, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dassau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33052341; PMCID: PMC7553166.
      View in: PubMed   Mentions:
    38. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038; PMCID: PMC9628766.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    39. Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells. Viruses. 2019 04 20; 11(4). Bernatchez JA, Coste M, Beck S, Wells GA, Luna LA, Clark AE, Zhu Z, Hecht D, Rich JN, Sohl CD, Purse BW, Siqueira-Neto JL. PMID: 31010044; PMCID: PMC6521205.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    40. Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus. Antimicrob Agents Chemother. 2018 10; 62(10). Bernatchez JA, Yang Z, Coste M, Li J, Beck S, Liu Y, Clark AE, Zhu Z, Luna LA, Sohl CD, Purse BW, Li R, Siqueira-Neto JL. PMID: 30061280; PMCID: PMC6153842.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    41. Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms. J Virol. 2018 03 15; 92(6). Clark AE, Sabalza M, Gordts PLSM, Spector DH. PMID: 29237845; PMCID: PMC5827393.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nat Struct Mol Biol. 2016 12; 23(12):1101-1110. Batra R, Stark TJ, Clark AE, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, Ares M, Spector DH, Yeo GW. PMID: 27775709; PMCID: PMC5140759.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    43. Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types. J Virol. 2016 02 01; 90(3):1259-77. Belzile JP, Sabalza M, Craig M, Clark AE, Morello CS, Spector DH. PMID: 26559848; PMCID: PMC4719619.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    44. Studies on the Contribution of Human Cytomegalovirus UL21a and UL97 to Viral Growth and Inactivation of the Anaphase-Promoting Complex/Cyclosome (APC/C) E3 Ubiquitin Ligase Reveal a Unique Cellular Mechanism for Downmodulation of the APC/C Subunits APC1, APC4, and APC5. J Virol. 2015 07; 89(13):6928-39. Clark AE, Spector DH. PMID: 25903336; PMCID: PMC4468507.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
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