Tsering Stobdan

Title(s)	Associate Project Scientist, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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A Boolean approach for novel hypoxia-related gene discovery. PLoS One. 2022; 17(8):e0273524. Stobdan T, Sahoo D, Haddad GG. PMID: 36006949; PMCID: PMC9409593.

View in: PubMed Mentions: Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Time Domains of Hypoxia Responses and -Omics Insights. Front Physiol. 2022; 13:885295. Yu JJ, Non AL, Heinrich EC, Gu W, Alcock J, Moya EA, Lawrence ES, Tift MS, O'Brien KA, Storz JF, Signore AV, Khudyakov JI, Milsom WK, Wilson SM, Beall CM, Villafuerte FC, Stobdan T, Julian CG, Moore LG, Fuster MM, Stokes JA, Milner R, West JB, Zhang J, Shyy JY, Childebayeva A, Vázquez-Medina JP, Pham LV, Mesarwi OA, Hall JE, Cheviron ZA, Sieker J, Blood AB, Yuan JX, Scott GR, Rana BK, Ponganis PJ, Malhotra A, Powell FL, Simonson TS. PMID: 36035495; PMCID: PMC9400701.

View in: PubMed Mentions: 4
Heterozygous Tropomodulin 3 mice have improved lung vascularization after chronic hypoxia. Hum Mol Genet. 2022 03 31; 31(7):1130-1140. Stobdan T, Jain PP, Xiong M, Bafna V, Yuan JX, Haddad GG. PMID: 34718575; PMCID: PMC8976430.

View in: PubMed Mentions: Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
Multiple mechanisms drive genomic adaptation to extreme O2 levels in Drosophila melanogaster. Nat Commun. 2021 02 12; 12(1):997. Iranmehr A, Stobdan T, Zhou D, Zhao H, Kryazhimskiy S, Bafna V, Haddad GG. PMID: 33579965; PMCID: PMC7881140.

View in: PubMed Mentions: 3 Fields:
Bio Biology Sci Science
Translation:Animals
Genetic interactions regulate hypoxia tolerance conferred by activating Notch in excitatory amino acid transporter 1-positive glial cells in Drosophila melanogaster. G3 (Bethesda). 2021 02 09; 11(2). Zhou D, Stobdan T, Visk D, Xue J, Haddad GG. PMID: 33576765; PMCID: PMC8022968.

View in: PubMed Mentions: 1 Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
Commentary: Novel Insight into the Genetic Basis of High Altitude Pulmonary Hypertension in Kyrgyz Highlanders. J Lung Health Dis. 2019; 3(2):29-30. Stobdan T, Haddad GG. PMID: 31304480; PMCID: PMC6625522.

View in: PubMed Mentions: 1
High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. PLoS One. 2019; 14(3):e0213474. Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG. PMID: 30861021; PMCID: PMC6413938.

View in: PubMed Mentions: 14 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals
Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlanders. Eur J Hum Genet. 2019 01; 27(1):150-159. Iranmehr A, Stobdan T, Zhou D, Poulsen O, Strohl KP, Aldashev A, Telenti A, Wong EHM, Kirkness EF, Venter JC, Bafna V, Haddad GG. PMID: 30254217; PMCID: PMC6303266.

View in: PubMed Mentions: 7 Fields:
Gen Genetics
Translation:Humans
Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia. J Mol Med (Berl). 2018 09; 96(9):975-982. Stobdan T, Zhou D, Williams AT, Cabrales P, Haddad GG. PMID: 30069745; PMCID: PMC6374051.

View in: PubMed Mentions: 5 Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
The 2018 Lake Louise Acute Mountain Sickness Score. High Alt Med Biol. 2018 03; 19(1):4-6. Roach RC, Hackett PH, Oelz O, Bärtsch P, Luks AM, MacInnis MJ, Baillie JK, Lake Louise AMS Score Consensus Committee. PMID: 29583031; PMCID: PMC6191821.

View in: PubMed Mentions: 112 Fields:
Bio Biology Med Medicine (General)
Translation:Humans
New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude. Mol Biol Evol. 2017 Dec 01; 34(12):3154-3168. Stobdan T, Akbari A, Azad P, Zhou D, Poulsen O, Appenzeller O, Gonzales GF, Telenti A, Wong EHM, Saini S, Kirkness EF, Venter JC, Bafna V, Haddad GG. PMID: 29029226; PMCID: PMC5850797.

View in: PubMed Mentions: 19 Fields:
Mol Molecular Biology
Translation:Humans Animals
High-altitude adaptation in humans: from genomics to integrative physiology. J Mol Med (Berl). 2017 Dec; 95(12):1269-1282. Azad P, Stobdan T, Zhou D, Hartley I, Akbari A, Bafna V, Haddad GG. PMID: 28951950; PMCID: PMC8936998.

View in: PubMed Mentions: 41 Fields:
Gen Genetics Mol Molecular Biology
Translation:Humans
Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. PMID: 26240367; PMCID: PMC4547246.

View in: PubMed Mentions: 26 Fields:
Sci Science
Translation:Humans Animals
Prevalence of hypertension at high altitude: cross-sectional survey in Ladakh, Northern India 2007-2011. BMJ Open. 2015 Apr 20; 5(4):e007026. Norboo T, Stobdan T, Tsering N, Angchuk N, Tsering P, Ahmed I, Chorol T, Kumar Sharma V, Reddy P, Singh SB, Kimura Y, Sakamoto R, Fukutomi E, Ishikawa M, Suwa K, Kosaka Y, Nose M, Yamaguchi T, Tsukihara T, Matsubayashi K, Otsuka K, Okumiya K. PMID: 25897026; PMCID: PMC4410116.

View in: PubMed Mentions: 19 Fields:
Med Medicine (General)
Translation:Humans PHPublic Health
Interactions between the genes of vasodilatation pathways influence blood pressure and nitric oxide level in hypertension. Am J Hypertens. 2015 Feb; 28(2):239-47. Kumar R, Kohli S, Mishra A, Garg R, Alam P, Stobdan T, Nejatizadeh A, Gupta M, Tyagi S, Pasha MA. PMID: 25159081.

View in: PubMed Mentions: 8 Fields:
Vas Vascular Diseases
Translation:Humans
Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biol. 2014 Feb 20; 15(2):R36. Udpa N, Ronen R, Zhou D, Liang J, Stobdan T, Appenzeller O, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Claydon VE, Hainsworth R, Gamboa JL, Zibenigus M, Zenebe G, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. PMID: 24555826; PMCID: PMC4054780.

View in: PubMed Mentions: 40 Fields:
Gen Genetics
Translation:Humans Animals Cells
Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 05; 93(3):452-62. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. PMID: 23954164; PMCID: PMC3769925.

View in: PubMed Mentions: 60 Fields:
Gen Genetics
Translation:Humans Animals Cells
Association of GNB3 C825T polymorphism with plasma electrolyte balance and susceptibility to hypertension. Genet Mol Biol. 2011 Oct; 34(4):553-6. Nejatizadeh A, Kumar R, Stobdan T, Pasha MQ. PMID: 22215956; PMCID: PMC3229107.

View in: PubMed Mentions: 6
Polymorphisms of renin--angiotensin system genes as a risk factor for high-altitude pulmonary oedema. J Renin Angiotensin Aldosterone Syst. 2011 Jun; 12(2):93-101. Stobdan T, Ali Z, Khan AP, Nejatizadeh A, Ram R, Thinlas T, Mohammad G, Norboo T, Himashree G, Qadar Pasha M. PMID: 21393362.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Humans
Population based study to assess prevalence and risk factors of gastroesophageal reflux disease in a high altitude area. Indian J Gastroenterol. 2011 May; 30(3):135-43. Kumar S, Sharma S, Norboo T, Dolma D, Norboo A, Stobdan T, Rohatgi S, Munot K, Ahuja V, Saraya A. PMID: 21181325.

View in: PubMed Mentions: 19 Fields:
Gas Gastroenterology
Translation:Humans
EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18961-6. Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A, Indian Genome Variation Consortium, Prasher B, Mukerji M. PMID: 20956315; PMCID: PMC2973881.

View in: PubMed Mentions: 63 Fields:
Sci Science
Translation:Humans
Probable role of beta2-adrenergic receptor gene haplotype in high-altitude pulmonary oedema. Respirology. 2010 May; 15(4):651-8. Stobdan T, Kumar R, Mohammad G, Thinlas T, Norboo T, Iqbal M, Pasha MA. PMID: 20546540.

View in: PubMed Mentions: 4 Fields:
Pul Pulmonary Medicine
Translation:Humans
Differences in the control of breathing between Himalayan and sea-level residents. J Physiol. 2010 May 01; 588(Pt 9):1591-606. Slessarev M, Prisman E, Ito S, Watson RR, Jensen D, Preiss D, Greene R, Norboo T, Stobdan T, Diskit D, Norboo A, Kunzang M, Appenzeller O, Duffin J, Fisher JA. PMID: 20194122; PMCID: PMC2876812.

View in: PubMed Mentions: 5 Fields:
Phy Physiology
Translation:Humans
CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension. Clin Biochem. 2010 Jan; 43(1-2):136-41. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Tyagi S, Jain SK, Pasha MA. PMID: 19786005.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry
Translation:Humans
Adaptation and mal-adaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns. PLoS One. 2008 Jun 04; 3(6):e2342. Xing G, Qualls C, Huicho L, Rivera-Ch M, River-Ch M, Stobdan T, Slessarev M, Prisman E, Ito S, Ito S, Wu H, Norboo A, Dolma D, Kunzang M, Norboo T, Gamboa JL, Claydon VE, Fisher J, Zenebe G, Gebremedhin A, Hainsworth R, Verma A, Appenzeller O. PMID: 18523639; PMCID: PMC2396283.

View in: PubMed Mentions: 32 Fields:
Med Medicine (General)Sci Science
Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. J Hypertens. 2008 Jun; 26(6):1094-101. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Javed S, Pasha MQ. PMID: 18475146.

View in: PubMed Mentions: 10 Fields:
Vas Vascular Diseases
Translation:Humans
The genetic aspects of pre-eclampsia: achievements and limitations. Biochem Genet. 2008 Aug; 46(7-8):451-79. Nejatizadeh A, Stobdan T, Malhotra N, Pasha MA. PMID: 18437552.

View in: PubMed Mentions: 14 Fields:
Mol Molecular Biology
Translation:Humans
Genetic landscape of the people of India: a canvas for disease gene exploration. J Genet. 2008 Apr; 87(1):3-20. Indian Genome Variation Consortium. PMID: 18560169.

View in: PubMed Mentions: 125 Fields:
Gen Genetics
Translation:Humans Cells
Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. Free Radic Biol Med. 2008 Jun 01; 44(11):1912-8. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Sikdar S, Gupta M, Javed S, Pasha MA. PMID: 18325347.

View in: PubMed Mentions: 15 Fields:
Bio Biochemistry Med Medicine (General)
Translation:Humans
High altitude adaptation: genetic perspectives. High Alt Med Biol. 2008; 9(2):140-7. Stobdan T, Karar J, Pasha MA. PMID: 18578645.

View in: PubMed Mentions: 11 Fields:
Bio Biology Med Medicine (General)
Translation:Humans
Life on the Qinghai-Tibetan Plateau. Proceedings of the 6th World Congress on Mountain Medicine and High Altitude Physiology. Genomics of high altitude adaptation and maladaptation. 2007; 374-386.
Susceptibility to high altitude pulmonary oedema: role of ACE and ET-1 polymorphisms. Thorax. 2006 Nov; 61(11):1011-2. Charu R, Stobdan T, Ram RB, Khan AP, Qadar Pasha MA, Norboo T, Afrin F. PMID: 17071838; PMCID: PMC2121168.

View in: PubMed Mentions: 13 Fields:
Pul Pulmonary Medicine
Translation:Humans
Predominance of interaction among wild-type alleles of CYP11B2 in Himalayan natives associates with high-altitude adaptation. Biochem Biophys Res Commun. 2006 Sep 22; 348(2):735-40. Rajput C, Arif E, Vibhuti A, Stobdan T, Khan AP, Norboo T, Afrin F, Qadar Pasha MA. PMID: 16893516.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry Bio Biophysics
Translation:Humans
The Indian Genome Variation database (IGVdb): a project overview. Hum Genet. 2005 Oct; 118(1):1-11. Indian Genome Variation Consortium. PMID: 16133172.

View in: PubMed Mentions: 53 Fields:
Gen Genetics
Translation:Humans