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    Tsering Stobdan

    TitleAssistant Project Scientist
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0735
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Azad P, Stobdan T, Zhou D, Hartley I, Akbari A, Bafna V, Haddad GG. High-altitude adaptation in humans: from genomics to integrative physiology. J Mol Med (Berl). 2017 Sep 26. PMID: 28951950.
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      2. Stobdan T, Akbari A, Azad P, Zhou D, Poulsen O, Appenzeller O, Gonzales GF, Telenti A, Wong EHM, Saini S, Kirkness EF, Venter JC, Bafna V, Haddad GG. New insights into the genetic basis of Monge's disease and adaptation to high-altitude. Mol Biol Evol. 2017 Sep 19. PMID: 29029226.
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      3. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. PMID: 26240367; PMCID: PMC4547246.
      4. Norboo T, Stobdan T, Tsering N, Angchuk N, Tsering P, Ahmed I, Chorol T, Kumar Sharma V, Reddy P, Singh SB, Kimura Y, Sakamoto R, Fukutomi E, Ishikawa M, Suwa K, Kosaka Y, Nose M, Yamaguchi T, Tsukihara T, Matsubayashi K, Otsuka K, Okumiya K. Prevalence of hypertension at high altitude: cross-sectional survey in Ladakh, Northern India 2007-2011. BMJ Open. 2015 Apr 20; 5(4):e007026. PMID: 25897026; PMCID: PMC4410116.
      5. Kumar R, Kohli S, Mishra A, Garg R, Alam P, Stobdan T, Nejatizadeh A, Gupta M, Tyagi S, Pasha MA. Interactions between the genes of vasodilatation pathways influence blood pressure and nitric oxide level in hypertension. Am J Hypertens. 2015 Feb; 28(2):239-47. PMID: 25159081.
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      6. Udpa N, Ronen R, Zhou D, Liang J, Stobdan T, Appenzeller O, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Claydon VE, Hainsworth R, Gamboa JL, Zibenigus M, Zenebe G, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biol. 2014 Feb 20; 15(2):R36. PMID: 24555826; PMCID: PMC4054780.
      7. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 05; 93(3):452-62. PMID: 23954164; PMCID: PMC3769925.
      8. Nejatizadeh A, Kumar R, Stobdan T, Pasha MQ. Association of GNB3 C825T polymorphism with plasma electrolyte balance and susceptibility to hypertension. Genet Mol Biol. 2011 Oct; 34(4):553-6. PMID: 22215956; PMCID: PMC3229107.
      9. Stobdan T, Ali Z, Khan AP, Nejatizadeh A, Ram R, Thinlas T, Mohammad G, Norboo T, Himashree G, Qadar Pasha M. Polymorphisms of renin--angiotensin system genes as a risk factor for high-altitude pulmonary oedema. J Renin Angiotensin Aldosterone Syst. 2011 Jun; 12(2):93-101. PMID: 21393362.
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      10. Kumar S, Sharma S, Norboo T, Dolma D, Norboo A, Stobdan T, Rohatgi S, Munot K, Ahuja V, Saraya A. Population based study to assess prevalence and risk factors of gastroesophageal reflux disease in a high altitude area. Indian J Gastroenterol. 2011 May; 30(3):135-43. PMID: 21181325.
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      11. Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A, Prasher B, Mukerji M. EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18961-6. PMID: 20956315; PMCID: PMC2973881.
      12. Stobdan T, Kumar R, Mohammad G, Thinlas T, Norboo T, Iqbal M, Pasha MA. Probable role of beta2-adrenergic receptor gene haplotype in high-altitude pulmonary oedema. Respirology. 2010 May; 15(4):651-8. PMID: 20546540.
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      13. Slessarev M, Prisman E, Ito S, Watson RR, Jensen D, Preiss D, Greene R, Norboo T, Stobdan T, Diskit D, Norboo A, Kunzang M, Appenzeller O, Duffin J, Fisher JA. Differences in the control of breathing between Himalayan and sea-level residents. J Physiol. 2010 May 01; 588(Pt 9):1591-606. PMID: 20194122; PMCID: PMC2876812.
      14. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Tyagi S, Jain SK, Pasha MA. CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension. Clin Biochem. 2010 Jan; 43(1-2):136-41. PMID: 19786005.
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      15. Xing G, Qualls C, Huicho L, Rivera-Ch M, River-Ch M, Stobdan T, Slessarev M, Prisman E, Ito S, Ito S, Wu H, Norboo A, Dolma D, Kunzang M, Norboo T, Gamboa JL, Claydon VE, Fisher J, Zenebe G, Gebremedhin A, Hainsworth R, Verma A, Appenzeller O. Adaptation and mal-adaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns. PLoS One. 2008 Jun 04; 3(6):e2342. PMID: 18523639; PMCID: PMC2396283.
      16. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Javed S, Pasha MQ. Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. J Hypertens. 2008 Jun; 26(6):1094-101. PMID: 18475146.
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      17. Nejatizadeh A, Stobdan T, Malhotra N, Pasha MA. The genetic aspects of pre-eclampsia: achievements and limitations. Biochem Genet. 2008 Aug; 46(7-8):451-79. PMID: 18437552.
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      18. Genetic landscape of the people of India: a canvas for disease gene exploration. J Genet. 2008 Apr; 87(1):3-20. PMID: 18560169.
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      19. Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Sikdar S, Gupta M, Javed S, Pasha MA. Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. Free Radic Biol Med. 2008 Jun 01; 44(11):1912-8. PMID: 18325347.
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      20. Stobdan T, Karar J, Pasha MA. High altitude adaptation: genetic perspectives. High Alt Med Biol. 2008; 9(2):140-7. PMID: 18578645.
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      21. Charu R, Stobdan T, Ram RB, Khan AP, Qadar Pasha MA, Norboo T, Afrin F. Susceptibility to high altitude pulmonary oedema: role of ACE and ET-1 polymorphisms. Thorax. 2006 Nov; 61(11):1011-2. PMID: 17071838; PMCID: PMC2121168.
      22. Rajput C, Arif E, Vibhuti A, Stobdan T, Khan AP, Norboo T, Afrin F, Qadar Pasha MA. Predominance of interaction among wild-type alleles of CYP11B2 in Himalayan natives associates with high-altitude adaptation. Biochem Biophys Res Commun. 2006 Sep 22; 348(2):735-40. PMID: 16893516.
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