Paul Kim

Title(s)Assistant Clinical Professor, Medicine
SchoolHealth Sciences
Address9300 Campus Point Drive #7411
La Jolla CA 92037
Phone858-246-0638
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    Collapse Biography 
    Collapse Education and Training
    UCSD, San Diego, CA06/2017Advanced Heart Failure and Transplant
    Stanford University, Palo Alto, CA06/2016Cardiology
    Stanford University, Palo Alto, CA06/2013Advanced Cardiovascular Imaging
    Stanford University, Palo Alto, CA06/2011Internal Medicine
    UCLA, Los Angeles, CAMD05/2008Medicine
    Collapse Awards and Honors
    UC San Diego2019National Center of Leadership in Academic Medicine
    Stanford University2016Edwin Alderman Award for Excellence in Clinical Research
    Stanford University2015Stanford Translation Research and Applied Medicine Pilot Grant
    Heart Failure Society of America2015HFSA Clinical Research Fellowship Award
    American Heart Association2012AHA Melvin Judkins Young Investigator Award
    UC Riverside2004Summa Cum Laude
    UC Riverside2001  - 2004Regents Scholarship

    Collapse Overview 
    Collapse Overview
    Specializes in Heart Failure, Heart Transplant, Mechanical Circulatory Support and Cardiac MRI/CT. Research interests include cardiac allograft vasculopathy and improving longevity of heart transplant patients through advancing molecular imaging and our understanding of transplant immunology.
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    Collapse Research 
    Collapse Research Activities and Funding
    KL2TR001444
    NIH/NCATS KL2TR001444Dec 1, 2020 - Nov 30, 2023
    Role: Principal Investigator
    Role Description: The goal of this study is understanding of immunotolerance and allograft longevity in heart-transplant patients.
    Use of dd-cfDNA to Detect Rejection in Cardiac Allograft Patients
    Natera Nov 1, 2020
    Role: Site Principal Investigator
    Role Description: To measure and statistically compare dd-cfDNA levels between 2 groups of cardiac transplant patients defined by biopsy results: Clinical Group 1 with no signs of rejection and Clinical Group 2 where any kind of rejection (any grade) is found, and compare these values to those measured using the same assay in a general population cohort, as found in published literature.
    Surveillance HeartCare Outcomes Registry (SHORE)
    CareDx Jun 1, 2019 - May 31, 2024
    Role: Site Principal Investigator
    Role Description: The primary study objective is to assess the clinical utility of surveillance using HeartCare testing services, in association with clinical care of heart transplant recipients.
    Identifying an Immune-mediated Mechanism in Nonspecific Allograft Dysfunction of Heart-Transplant Patients
    ACTRI Oct 15, 2018 - Oct 7, 2019
    Role: Principal Investigator
    Role Description: We will attempt to identify an immune-mediated mechanism in nonspecific graft dysfunction of heart-transplant patients. The life after heart transplantation is limited by gradual weakening of the heart after transplant with an average survival of 10 years. We currently do not know the cause in up to 40% of heart-transplant patients, called nonspecific graft dysfunction, and patients with nonspecific graft dysfunction are at much higher risk for death. We will focus our research on T cells, a type of white blood cell. T cells have been shown to cause weakening of the heart in heart-transplant patients in different ways. We believe there is another way that T cells cause disease that is not prevented by our current medications. We will use new, cutting-edge technology to analyze individual T cells in heart-transplant patients to understand why some patients develop nonspecific graft dysfunction. These findings will be critical to improving our understanding of heart-transplant biology and most importantly, preventing heart failure in transplant patients and improving their lives.
    Evaluation of Myocardial Perfusion and Immune Cell Response in Allograft Dysfunction of Heart-Transplant Patients
    AHA 18CDA34110250Jul 1, 2018 - Jun 30, 2021
    Role: Principal Investigator
    Role Description: The goal of this study is evaluation of abnormal hearts after heart-transplantation in patients
    Evaluation of Allograft Dysfunction in Heart-Transplant Patients
    Astellas Pharma Investigator Initiated Study Apr 1, 2017 - Dec 28, 2018
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Advances and New Insights in Post-Transplant Care: From Sequencing to Imaging. Current Treatment Options in Cardiovascular Medicine. 2021; 22(32):0-19. Battikha, CE, Selevany, I, Kim PJ.
    2. Heart Failure: A Companion to Braunwald’s Heart Disease. 2019; 403-417. Greenberg, B, Kim P, Kahn A.
    3. Galectin-3 After Heart Transplantation: Does it Get Better? JACC Heart Fail. 2016 11; 4(11):857-859. Maisel A, Kim P, Stendardi W. PMID: 27810079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Telmisartan in the diabetic murine model of acute myocardial infarction: dual contrast manganese-enhanced and delayed enhancement MRI evaluation of the peri-infarct region. Cardiovasc Diabetol. 2016 Feb 05; 15:24. Toma I, Kim PJ, Dash R, McConnell MV, Nishimura D, Harnish P, Yang PC. PMID: 26846539.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    5. Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model. J Am Heart Assoc. 2015 Jul 27; 4(7). Dash R, Kim PJ, Matsuura Y, Ikeno F, Metzler S, Huang NF, Lyons JK, Nguyen PK, Ge X, Foo CW, McConnell MV, Wu JC, Yeung AC, Harnish P, Yang PC. PMID: 26215972.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    6. Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium. Circ Res. 2015 Mar 27; 116(7):e40-50. Kim PJ, Mahmoudi M, Ge X, Matsuura Y, Toma I, Metzler S, Kooreman NG, Ramunas J, Holbrook C, McConnell MV, Blau H, Harnish P, Rulifson E, Yang PC. PMID: 25654979.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    7. Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes. Am J Transl Res. 2014; 6(6):724-35. Burridge PW, Metzler SA, Nakayama KH, Abilez OJ, Simmons CS, Bruce MA, Matsuura Y, Kim P, Wu JC, Butte M, Huang NF, Yang PC. PMID: 25628783.
      View in: PubMed   Mentions: 22  
    8. Bone marrow cell therapy in clinical trials: a review of the literature. Rev Recent Clin Trials. 2012 Aug; 7(3):204-13. Kim PJ, Yang PC. PMID: 22540909.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Contrast echocardiography: finding its place in stem cell therapy. Minerva Cardioangiol. 2011 Oct; 59(5):491-7. Kim PJ, Yang PC. PMID: 21983309.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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