Paul Kim

Title(s)Assistant Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    UCSD, San Diego, CAMAS06/2023Master's in Clinical Research
    UCSD, San Diego, CA06/2017Advanced Heart Failure and Transplant
    Stanford University, Palo Alto, CA06/2016Cardiology
    Stanford University, Palo Alto, CA06/2013Advanced Cardiovascular Imaging
    Stanford University, Palo Alto, CA06/2011Internal Medicine
    UCLA, Los Angeles, CAMD05/2008Medicine
    UCR, Riverside, CABS06/2004Biomedical Sciences
    Collapse Awards and Honors
    UCSD2019National Center of Leadership in Academic Medicine
    Stanford University2016Edwin Alderman Award for Excellence in Clinical Research
    Stanford University2015Stanford Translation Research and Applied Medicine Pilot Grant
    Heart Failure Society of America2015HFSA Clinical Research Fellowship Award
    American Heart Association2012AHA Melvin Judkins Young Investigator Award
    UCR2004Summa Cum Laude
    UCR2001  - 2004Regents Scholarship

    Collapse Overview 
    Collapse Overview
    Specializes in Heart Failure, Heart Transplant, Mechanical Circulatory Support and Cardiac MRI/CT. Research interests include cardiac allograft vasculopathy and improving longevity of heart transplant patients through advancing molecular imaging and our understanding of transplant immunology.
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    Assessment and Significance of Allograft Rejection in Heart Transplantation using HistoMap and Formalin Fixed Paraffin Embedded Tissue
    CareDx Jun 1, 2023 - Apr 30, 2024
    Role: Co-Investigator
    Description: The goal of this study is the evaluate the utility of digital spatial profiling in different forms of acute rejection in heart transplant patients.
    Identification of tissue cellular and transcriptomic signature for improving diagnostic sensitivity for cardiac sarcoidosis
    NIH/NCATS/ACTRI May 1, 2023 - Apr 30, 2024
    Role: Principal Investigator
    Description: The goal of this study is to improve the diagnostic sensitivity of endomyocardial biopsies for cardiac sarcoidosis through identification of a unique transcriptomic signature.
    Development of non-invasive cell-free DNA to supplant invasive biopsy in heart transplantation (DEFINE-HT)
    Natera Apr 1, 2023 - Oct 30, 2024
    Role: Site Principal Investigator
    Description: Prospective multicenter observational study evaluating the use of donor derived cell-free DNA in the detection of acute rejection in heart transplant patients
    4D Compressed Sensing Flow
    NIH/NCATS/ACTRI Dec 1, 2022 - Apr 30, 2023
    Role: Co-Investigator
    NIH/NCATS KL2TR001444Dec 1, 2020 - Nov 30, 2023
    Role: Principal Investigator
    Description: The goal of this study is understanding of immunotolerance and allograft longevity in heart-transplant patients.
    Use of dd-cfDNA to Detect Rejection in Cardiac Allograft Patients
    Natera Nov 1, 2020 - Feb 1, 2022
    Role: Site Principal Investigator
    Description: To measure and statistically compare dd-cfDNA levels between 2 groups of cardiac transplant patients defined by biopsy results: Clinical Group 1 with no signs of rejection and Clinical Group 2 where any kind of rejection (any grade) is found, and compare these values to those measured using the same assay in a general population cohort, as found in published literature.
    Surveillance HeartCare Outcomes Registry (SHORE)
    CareDx Jun 1, 2019 - May 31, 2024
    Role: Site Principal Investigator
    Description: The primary study objective is to assess the clinical utility of surveillance using HeartCare testing services, in association with clinical care of heart transplant recipients.
    Identifying an Immune-mediated Mechanism in Nonspecific Allograft Dysfunction of Heart-Transplant Patients
    NIH/NCATS/ACTRI Oct 15, 2018 - Oct 7, 2019
    Role: Principal Investigator
    Description: We will attempt to identify an immune-mediated mechanism in nonspecific graft dysfunction of heart-transplant patients. The life after heart transplantation is limited by gradual weakening of the heart after transplant with an average survival of 10 years. We currently do not know the cause in up to 40% of heart-transplant patients, called nonspecific graft dysfunction, and patients with nonspecific graft dysfunction are at much higher risk for death. We will focus our research on T cells, a type of white blood cell. T cells have been shown to cause weakening of the heart in heart-transplant patients in different ways. We believe there is another way that T cells cause disease that is not prevented by our current medications. We will use new, cutting-edge technology to analyze individual T cells in heart-transplant patients to understand why some patients develop nonspecific graft dysfunction. These findings will be critical to improving our understanding of heart-transplant biology and most importantly, preventing heart failure in transplant patients and improving their lives.
    Evaluation of Myocardial Perfusion and Immune Cell Response in Allograft Dysfunction of Heart-Transplant Patients
    AHA 18CDA34110250Jul 1, 2018 - Jun 30, 2021
    Role: Principal Investigator
    Description: The goal of this study is evaluation of abnormal hearts after heart-transplantation in patients
    Evaluation of Allograft Dysfunction in Heart-Transplant Patients
    Astellas Pharma Investigator Initiated Study Apr 1, 2017 - Dec 28, 2018
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Incidence of Acute Rejection Compared With Endomyocardial Biopsy Complications for Heart Transplant Patients in the Contemporary Era. Transplantation. 2023 Dec 15. Cusi V, Vaida F, Wettersten N, Rodgers N, Tada Y, Gerding B, Urey MA, Greenberg B, Adler ED, Kim PJ. PMID: 38098137.
      View in: PubMed   Mentions:    Fields:    
    2. Antibody Mediated Rejection is not Associated with Worse Survival in Adherent Heart Transplant Patients in the Contemporary Era. medRxiv. 2023 Dec 08. Kim PJ, Cusi V, Cardenas A, Tada Y, Vaida F, Wettersten N, Chak J, Bijlani P, Pretorius V, Urey MA, Morris GP, Lin G. PMID: 38106112; PMCID: PMC10723500.
      View in: PubMed   Mentions:
    3. The Cardiac Amyloidosis Registry Study (CARS): Rationale, Design and Methodology. J Card Fail. 2023 Oct 30. Stern LK, Grodin JL, Maurer MS, Ruberg FL, Patel AR, Khouri MG, Roth LR, Aras MA, Bhardwaj A, Bhattacharya P, Brailovsky Y, Drachman BM, Ebong IA, Fine NM, Gaggin H, Gopal D, Griffin J, Judge D, Kim P, Mitchell J, Mitter SS, Mohan RC, Ramos H, Reyentovich A, Sheikh FH, Sperry B, Carter S, Urey M, Vaishnav J, Vest AR, Kittleson MM, Patel JK. PMID: 37907148.
      View in: PubMed   Mentions:    Fields:    
    4. Benefit versus Risk of Endomyocardial Biopsy for Heart Transplant Patients in the Contemporary Era. medRxiv. 2023 Jul 28. Cusi V, Vaida F, Wettersten N, Rodgers N, Tada Y, Gerding B, Greenberg B, Urey MA, Adler E, Kim PJ. PMID: 37293037; PMCID: PMC10246074.
      View in: PubMed   Mentions:
    5. Comparison of two donor-derived cell-free DNA tests and a blood gene-expression profile test in heart transplantation. Clin Transplant. 2023 06; 37(6):e14984. Rodgers N, Gerding B, Cusi V, Vaida F, Tada Y, Morris GP, Adler ED, Stehlik J, Kim PJ. PMID: 37036133; PMCID: PMC10330254.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Qualitative and Quantitative Stress Perfusion Cardiac Magnetic Resonance in Clinical Practice: A Comprehensive Review. Diagnostics (Basel). 2023 Jan 31; 13(3). Zhou W, Sin J, Yan AT, Wang H, Lu J, Li Y, Kim P, Patel AR, Ng MY. PMID: 36766629; PMCID: PMC9914769.
      View in: PubMed   Mentions:
    7. Pressure Volume Loop Analysis of the Right Ventricle in Heart Failure With Computed Tomography. ASAIO J. 2023 02 01; 69(2):e66-e72. Scott A, Chen Z, Hernandez Hernandez D, Kligerman S, Kim P, Tran H, Adler E, Contijoch F. PMID: 36521051; PMCID: PMC9892274.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Immunodominant MHC-II (Major Histocompatibility Complex II) Restricted Epitopes in Human Apolipoprotein B. Circ Res. 2022 07 22; 131(3):258-276. Roy P, Sidney J, Lindestam Arlehamn CS, Phillips E, Mallal S, Armstrong Suthahar SS, Billitti M, Rubiro P, Marrama D, Drago F, Vallejo J, Suryawanshi V, Orecchioni M, Makings J, Kim PJ, McNamara CA, Peters B, Sette A, Ley K. PMID: 35766025; PMCID: PMC9536649.
      View in: PubMed   Mentions: 5     Fields:    
    9. Point-of-care prediction model of loop gain in patients with obstructive sleep apnea: development and validation. BMC Pulm Med. 2022 Apr 25; 22(1):158. Schmickl CN, Orr JE, Kim P, Nokes B, Sands S, Manoharan S, McGinnis L, Parra G, DeYoung P, Owens RL, Malhotra A. PMID: 35468829; PMCID: PMC9036750.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. A novel donor-derived cell-free DNA assay for the detection of acute rejection in heart transplantation. J Heart Lung Transplant. 2022 07; 41(7):919-927. Kim PJ, Olymbios M, Siu A, Wever Pinzon O, Adler E, Liang N, Swenerton R, Sternberg J, Kaur N, Ahmed E, Chen YA, Fehringer G, Demko ZP, Billings PR, Stehlik J. PMID: 35577713; PMCID: PMC9670834.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    11. Preoperative Computed Tomography Assessment of Risk of Right Ventricle Failure After Left Ventricular Assist Device Placement. ASAIO J. 2023 01 01; 69(1):69-75. Scott A, Kligerman S, Hernandez Hernandez D, Kim P, Tran H, Pretorius V, Adler E, Contijoch F. PMID: 36583772; PMCID: PMC10684273.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Advances and New Insights in Post-Transplant Care: From Sequencing to Imaging. Current Treatment Options in Cardiovascular Medicine. 2021; 22(32):0-19. Battikha, CE, Selevany, I, Kim PJ.
    13. Heart Failure: A Companion to Braunwald’s Heart Disease. 2019; 403-417. Greenberg, B, Kim P, Kahn A.
    14. Molecular Imaging of the Transplanted Heart: A Mechanistic Approach to Graft Survival. Current Cardiovascular Imaging Reports. 2017; 10(8). Stendardi, William, Kim, Paul, Hsiao, Albert.
    15. Galectin-3 After Heart Transplantation: Does it Get Better? JACC Heart Fail. 2016 11; 4(11):857-859. Maisel A, Kim P, Stendardi W. PMID: 27810079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Telmisartan in the diabetic murine model of acute myocardial infarction: dual contrast manganese-enhanced and delayed enhancement MRI evaluation of the peri-infarct region. Cardiovasc Diabetol. 2016 Feb 05; 15:24. Toma I, Kim PJ, Dash R, McConnell MV, Nishimura D, Harnish P, Yang PC. PMID: 26846539; PMCID: PMC4743104.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model. J Am Heart Assoc. 2015 Jul 27; 4(7). Dash R, Kim PJ, Matsuura Y, Ikeno F, Metzler S, Huang NF, Lyons JK, Nguyen PK, Ge X, Foo CW, McConnell MV, Wu JC, Yeung AC, Harnish P, Yang PC. PMID: 26215972; PMCID: PMC4608088.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium. Circ Res. 2015 Mar 27; 116(7):e40-50. Kim PJ, Mahmoudi M, Ge X, Matsuura Y, Toma I, Metzler S, Kooreman NG, Ramunas J, Holbrook C, McConnell MV, Blau H, Harnish P, Rulifson E, Yang PC. PMID: 25654979; PMCID: PMC4380765.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    19. Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes. Am J Transl Res. 2014; 6(6):724-35. Burridge PW, Metzler SA, Nakayama KH, Abilez OJ, Simmons CS, Bruce MA, Matsuura Y, Kim P, Wu JC, Butte M, Huang NF, Yang PC. PMID: 25628783; PMCID: PMC4297340.
      View in: PubMed   Mentions: 27  
    20. Bone marrow cell therapy in clinical trials: a review of the literature. Rev Recent Clin Trials. 2012 Aug; 7(3):204-13. Kim PJ, Yang PC. PMID: 22540909.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Contrast echocardiography: finding its place in stem cell therapy. Minerva Cardioangiol. 2011 Oct; 59(5):491-7. Kim PJ, Yang PC. PMID: 21983309.
      View in: PubMed   Mentions:    Fields:    Translation:Humans