Tatum Simonson

Title(s)Associate Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of Utah, Salt Lake City, UTPhD12/2011Human Genetics
    Collapse Awards and Honors
    Rosalind Franklin Society2022Rosalind Franklin Award in Science
    National Geographic Society2018Explorer Award
    American Physiological Society2017Giles F. Filley Memorial Award
    Francis Family Foundation2013Parker B. Francis Fellowship
    American Physiological Society2012Physiological Genomics Fellowship
    University of Utah2012James W. Prahl Award, Outstanding PhD in Biomedical Sciences, School of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Respiratory and genomic contributions to adaptive/maladaptive hypoxia responses
    NIH R01HL145470May 10, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Integrating Physiology and Genomics to Reveal Functional Adaptation in High-Altitude Tibetans
    NIH R00HL118215Jan 17, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Integrating physiology and genomics to reveal functional adaptation in high-altit
    NIH K99HL118215Jan 17, 2014 - Jan 18, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Higher oxygen content and transport characterize high-altitude ethnic Tibetan women with the highest lifetime reproductive success. Proc Natl Acad Sci U S A. 2024 Nov 05; 121(45):e2403309121. Ye S, Sun J, Craig SR, Di Rienzo A, Witonsky D, Yu JJ, Moya EA, Simonson TS, Powell FL, Basnyat B, Strohl KP, Hoit BD, Beall CM. PMID: 39432765.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Transcriptome meta-analysis of Kawasaki disease in humans and mice. Front Pediatr. 2024; 12:1423958. Gu W, Mirsaidi-Madjdabadi S, Ramirez F, Simonson TS, Makino A. PMID: 39350793; PMCID: PMC11440715.
      View in: PubMed   Mentions:
    3. Development of multiplexed orthogonal base editor (MOBE) systems. Nat Biotechnol. 2024 May 21. Cowan QT, Gu S, Gu W, Ranzau BL, Simonson TS, Komor AC. PMID: 38773305.
      View in: PubMed   Mentions: 1     Fields:    
    4. Tibetans exhibit lower hemoglobin concentration and decreased heart response to hypoxia during poikilocapnia at intermediate altitude relative to Han Chinese. Front Physiol. 2024; 15:1334874. Moya EA, Yu JJ, Brown S, Gu W, Lawrence ES, Carlson R, Brandes A, Wegeng W, Amann K, McIntosh SE, Powell FL, Simonson TS. PMID: 38784113; PMCID: PMC11112024.
      View in: PubMed   Mentions:
    5. Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders. Sci Adv. 2024 Feb 09; 10(6):eadj5661. Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, Cowan QT, Bruck PT, Mercader K, Alotaibi M, Long T, Hall JE, Moya EA, Bauk MA, Reeves JJ, Kong MC, Salem RM, Vizcardo-Galindo G, Macarlupu JL, Figueroa-Mujíca R, Bermudez D, Corante N, Gaio E, Fox KP, Salomaa V, Havulinna AS, Murray AJ, Malhotra A, Powel FL, Jain M, Komor AC, Cavalleri GL, Huff CD, Villafuerte FC, Simonson TS. PMID: 38335297; PMCID: PMC10857371.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia. Hypertension. 2024 Feb; 81(2):319-329. O'Brien KA, Gu W, Houck JA, Holzner LMW, Yung HW, Armstrong JL, Sowton AP, Baxter R, Darwin PM, Toledo-Jaldin L, Lazo-Vega L, Moreno-Aramayo AE, Miranda-Garrido V, Shortt JA, Matarazzo CJ, Yasini H, Burton GJ, Moore LG, Simonson TS, Murray AJ, Julian CG. PMID: 38018457; PMCID: PMC10841680.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Inflammation biomarkers in OSA, chronic obstructive pulmonary disease, and chronic obstructive pulmonary disease/OSA overlap syndrome. J Clin Sleep Med. 2023 08 01; 19(8):1447-1456. Sanchez-Azofra A, Gu W, Masso-Silva JA, Sanz-Rubio D, Marin-Oto M, Cubero P, Gil AV, Moya EA, Barnes LA, Mesarwi OA, Marin T, Simonson TS, Crotty Alexander LE, Marin JM, Malhotra A. PMID: 37082823; PMCID: PMC10394367.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Energy Metabolism Dysregulation in Chronic Kidney Disease. Kidney360. 2023 08 01; 4(8):1080-1094. Li Y, Gu W, Hepokoski M, Pham H, Tham R, Kim YC, Simonson TS, Singh P. PMID: 37222594; PMCID: PMC10476685.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Very Low Driving-Pressure Ventilation in Patients With COVID-19 Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation: A Physiologic Study. J Cardiothorac Vasc Anesth. 2023 03; 37(3):423-431. Odish M, Pollema T, Meier A, Hepokoski M, Yi C, Spragg R, Patel HH, Alexander LEC, Sun XS, Jain S, Simonson TS, Malhotra A, Owens RL. PMID: 36567221; PMCID: PMC9701579.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Preserved peak exercise capacity in Andean highlanders with excessive erythrocytosis both before and after isovolumic hemodilution. J Appl Physiol (1985). 2023 01 01; 134(1):36-49. Anza-Ramírez C, Gu W, Macarlupú JL, Figueroa-Mujíca RJ, Vizcardo-Galindo GA, Heinrich EC, Tift MS, Wagner HE, Wagner PD, Simonson TS, Villafuerte FC. PMID: 36417198; PMCID: PMC9762978.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Genomic insights into TASK-1 reveal functional roles in sleep apnea. Nat Genet. 2022 10; 54(10):1451-1452. Simonson TS, Moya EA, Malhotra A. PMID: 36195756; PMCID: PMC9556092.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Isovolemic hemodilution in chronic mountain sickness acutely worsens nocturnal oxygenation and sleep apnea severity. J Clin Sleep Med. 2022 10 01; 18(10):2423-2432. Sanchez-Azofra A, Villafuerte FC, DeYoung PN, Gilbertson D, Gu W, Moya EA, Vizcardo-Galindo G, Figueroa-Mujíca R, Anza-Ramirez C, Macarlupú JL, Pham LV, Wagner P, Malhotra A, Simonson TS, Mesarwi OA. PMID: 35855526; PMCID: PMC9516589.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Time Domains of Hypoxia Responses and -Omics Insights. Front Physiol. 2022; 13:885295. Yu JJ, Non AL, Heinrich EC, Gu W, Alcock J, Moya EA, Lawrence ES, Tift MS, O'Brien KA, Storz JF, Signore AV, Khudyakov JI, Milsom WK, Wilson SM, Beall CM, Villafuerte FC, Stobdan T, Julian CG, Moore LG, Fuster MM, Stokes JA, Milner R, West JB, Zhang J, Shyy JY, Childebayeva A, Vázquez-Medina JP, Pham LV, Mesarwi OA, Hall JE, Cheviron ZA, Sieker J, Blood AB, Yuan JX, Scott GR, Rana BK, Ponganis PJ, Malhotra A, Powell FL, Simonson TS. PMID: 36035495; PMCID: PMC9400701.
      View in: PubMed   Mentions: 6  
    14. Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype. Sleep. 2022 06 13; 45(6). Zhen X, Moya EA, Gautane M, Zhao H, Lawrence ES, Gu W, Barnes LA, Yuan JX, Jain PP, Xiong M, Catalan Serra P, Pham LV, Malhotra A, Simonson TS, Mesarwi OA. PMID: 34893914; PMCID: PMC9189937.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    15. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. Elife. 2022 04 12; 11. Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. PMID: 35411847; PMCID: PMC9005188.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    16. Diagnostic Accuracy of the Progressive Collapsing Foot Deformity (PCFD) Classification. Foot Ankle Int. 2022 06; 43(6):800-809. Li S, Zhu M, Gu W, Hamati M, Hunt KJ, de Cesar Netto C, Simonson TS, Myerson MS. PMID: 35301895.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Notch Signaling and Cross-Talk in Hypoxia: A Candidate Pathway for High-Altitude Adaptation. Life (Basel). 2022 Mar 16; 12(3). O'Brien KA, Murray AJ, Simonson TS. PMID: 35330188; PMCID: PMC8954738.
      View in: PubMed   Mentions: 9  
    18. High-Altitude Erythrocytosis: Mechanisms of Adaptive and Maladaptive Responses. Physiology (Bethesda). 2022 07 01; 37(4):0. Villafuerte FC, Simonson TS, Bermudez D, León-Velarde F. PMID: 35001654; PMCID: PMC9191173.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Targeting Mitochondria and Metabolism in Acute Kidney Injury. J Clin Med. 2021 Sep 03; 10(17). Li Y, Hepokoski M, Gu W, Simonson T, Singh P. PMID: 34501442; PMCID: PMC8432487.
      View in: PubMed   Mentions: 10  
    20. Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells. Front Physiol. 2021; 12:714785. Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. PMID: 34408668; PMCID: PMC8364962.
      View in: PubMed   Mentions:
    21. Halofuginone, a promising drug for treatment of pulmonary hypertension. Br J Pharmacol. 2021 09; 178(17):3373-3394. Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. PMID: 33694155; PMCID: PMC9792225.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    22. Impacts of Changes in Atmospheric O2 on Human Physiology. Is There a Basis for Concern? Front Physiol. 2021; 12:571137. Keeling RF, Powell FL, Shaffer G, Robbins PA, Simonson TS. PMID: 33737880; PMCID: PMC7960674.
      View in: PubMed   Mentions: 2  
    23. Silent hypoxaemia in COVID-19 patients. J Physiol. 2021 02; 599(4):1057-1065. Simonson TS, Baker TL, Banzett RB, Bishop T, Dempsey JA, Feldman JL, Guyenet PG, Hodson EJ, Mitchell GS, Moya EA, Nokes BT, Orr JE, Owens RL, Poulin M, Rawling JM, Schmickl CN, Watters JJ, Younes M, Malhotra A. PMID: 33347610; PMCID: PMC7902403.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    24. Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes. Pulm Circ. 2020 Oct-Dec; 10(4):2045894020968531. Romanoski CE, Qi X, Sangam S, Vanderpool RR, Stearman RS, Conklin A, Gonzalez-Garay M, Rischard F, Ayon RJ, Wang J, Simonson T, Babicheva A, Shi Y, Tang H, Makino A, Kanthi Y, Geraci MW, Garcia JGN, Yuan JX, Desai AA. PMID: 33343881; PMCID: PMC7727059.
      View in: PubMed   Mentions: 11  
    25. Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020948470. Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. PMID: 33294172; PMCID: PMC7707860.
      View in: PubMed   Mentions: 9  
    26. Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia. Front Physiol. 2020; 11:886. Tift MS, Alves de Souza RW, Weber J, Heinrich EC, Villafuerte FC, Malhotra A, Otterbein LE, Simonson TS. PMID: 32792988; PMCID: PMC7387684.
      View in: PubMed   Mentions: 11  
    27. Cross-Species Insights Into Genomic Adaptations to Hypoxia. Front Genet. 2020; 11:743. Pamenter ME, Hall JE, Tanabe Y, Simonson TS. PMID: 32849780; PMCID: PMC7387696.
      View in: PubMed   Mentions: 35  
    28. Seq-ing Higher Ground: Functional Investigation of Adaptive Variation Associated With High-Altitude Adaptation. Front Genet. 2020; 11:471. Hall JE, Lawrence ES, Simonson TS, Fox K. PMID: 32528523; PMCID: PMC7247851.
      View in: PubMed   Mentions: 5  
    29. Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women. Front Physiol. 2020; 11:437. Heinrich EC, Orr JE, Gilbertson D, Anza-Ramirez C, DeYoung PN, Djokic MA, Corante N, Vizcardo-Galindo G, Macarlupu JL, Gaio E, Powell FL, Malhotra A, Villafuerte FC, Simonson TS. PMID: 32435207; PMCID: PMC7219107.
      View in: PubMed   Mentions: 11  
    30. Variability in hypoxic response: Could genetics play a role? J Physiol. 2020 05; 598(10):1805-1806. Simonson TS, Malhotra A. PMID: 32281106; PMCID: PMC7450394.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Neuronal HIF-1α in the nucleus tractus solitarius contributes to ventilatory acclimatization to hypoxia. J Physiol. 2020 05; 598(10):2021-2034. Moya EA, Go A, Kim CB, Fu Z, Simonson TS, Powell FL. PMID: 32026480; PMCID: PMC7230006.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    32. Cognitive function and mood at high altitude following acclimatization and use of supplemental oxygen and adaptive servoventilation sleep treatments. PLoS One. 2019; 14(6):e0217089. Heinrich EC, Djokic MA, Gilbertson D, DeYoung PN, Bosompra NO, Wu L, Anza-Ramirez C, Orr JE, Powell FL, Malhotra A, Simonson TS. PMID: 31188839; PMCID: PMC6561544.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    33. Genetic variants at the EGLN1 locus associated with high-altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans. Ann Hum Genet. 2019 05; 83(3):171-176. Heinrich EC, Wu L, Lawrence ES, Cole AM, Anza-Ramirez C, Villafuerte FC, Simonson TS. PMID: 30719713; PMCID: PMC7920394.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    34. Giants in Chest Medicine: Emeritus Professor Peter D. Wagner, MD. Chest. 2019 01; 155(1):9-11. Simonson TS. PMID: 30616739.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Adaptive Servoventilation as Treatment for Central Sleep Apnea Due to High-Altitude Periodic Breathing in Nonacclimatized Healthy Individuals. High Alt Med Biol. 2018 06; 19(2):178-184. Orr JE, Heinrich EC, Djokic M, Gilbertson D, Deyoung PN, Anza-Ramirez C, Villafuerte FC, Powell FL, Malhotra A, Simonson T. PMID: 29641294; PMCID: PMC6014053.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. Evolutionary history of Tibetans inferred from whole-genome sequencing. PLoS Genet. 2017 04; 13(4):e1006675. Hu H, Petousi N, Glusman G, Yu Y, Bohlender R, Tashi T, Downie JM, Roach JC, Cole AM, Lorenzo FR, Rogers AR, Brunkow ME, Cavalleri G, Hood L, Alpatty SM, Prchal JT, Jorde LB, Robbins PA, Simonson TS, Huff CD. PMID: 28448578; PMCID: PMC5407610.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    37. Measurement of the distribution of ventilation-perfusion ratios in the human lung with proton MRI: comparison with the multiple inert-gas elimination technique. J Appl Physiol (1985). 2017 Jul 01; 123(1):136-146. Sá RC, Henderson AC, Simonson T, Arai TJ, Wagner H, Theilmann RJ, Wagner PD, Prisk GK, Hopkins SR. PMID: 28280105; PMCID: PMC5538816.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    38. Sea-level haemoglobin concentration is associated with greater exercise capacity in Tibetan males at 4200 m. Exp Physiol. 2015 Nov; 100(11):1256-62. Wagner PD, Simonson TS, Wei G, Wagner HE, Wuren T, Qin G, Yan M, Ge RL. PMID: 26454003.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans. Exp Physiol. 2015 Nov; 100(11):1263-8. Simonson TS, Huff CD, Witherspoon DJ, Prchal JT, Jorde LB. PMID: 26454145.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    40. Oxygen transport adaptations to exercise in native highland populations. Exp Physiol. 2015 Nov; 100(11):1231-2. Simonson TS, Wagner PD. PMID: 26575339.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Metabolic aspects of high-altitude adaptation in Tibetans. Exp Physiol. 2015 Nov; 100(11):1247-55. Ge RL, Simonson TS, Gordeuk V, Prchal JT, McClain DA. PMID: 26053282; PMCID: PMC10905973.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    42. Low haemoglobin concentration in Tibetan males is associated with greater high-altitude exercise capacity. J Physiol. 2015 Jul 15; 593(14):3207-18. Simonson TS, Wei G, Wagner HE, Wuren T, Qin G, Yan M, Wagner PD, Ge RL. PMID: 25988759; PMCID: PMC4532538.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    43. Altitude Adaptation: A Glimpse Through Various Lenses. High Alt Med Biol. 2015 Jun; 16(2):125-37. Simonson TS. PMID: 26070057; PMCID: PMC4490743.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    44. Reply: To PMID 25172885. Exp Physiol. 2015 Mar; 100(3):342. Simonson TS, Wei G, Wagner HE, Wuren T, Bui A, Fine JM, Qin G, Beltrami FG, Yan M, Wagner PD, Ge RL. PMID: 25720665.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Increased blood-oxygen binding affinity in Tibetan and Han Chinese residents at 4200 m. Exp Physiol. 2014 Dec 01; 99(12):1624-35. Simonson TS, Wei G, Wagner HE, Wuren T, Bui A, Fine JM, Qin G, Beltrami FG, Yan M, Wagner PD, Ge RL. PMID: 25172885; PMCID: PMC4272572.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    46. A genetic mechanism for Tibetan high-altitude adaptation. Nat Genet. 2014 Sep; 46(9):951-6. Lorenzo FR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuren T, Ri-Li G, McClain DA, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenza GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin WG, Koivunen P, Prchal JT. PMID: 25129147; PMCID: PMC4473257.
      View in: PubMed   Mentions: 195     Fields:    Translation:Humans
    47. Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations. PLoS One. 2014; 9(3):e88252. Wuren T, Simonson TS, Qin G, Xing J, Huff CD, Witherspoon DJ, Jorde LB, Ge RL. PMID: 24642866; PMCID: PMC3958363.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    48. Less is more: blunted responses to hypoxia revealed in sea-level Tibetans. J Appl Physiol (1985). 2014 Apr 01; 116(7):711-2. Simonson TS, Powell FL. PMID: 24114703.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians. PLoS Genet. 2013; 9(7):e1003634. Xing J, Wuren T, Simonson TS, Watkins WS, Witherspoon DJ, Wu W, Qin G, Huff CD, Jorde LB, Ge RL. PMID: 23874230; PMCID: PMC3715426.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    50. Metabolic insight into mechanisms of high-altitude adaptation in Tibetans. Mol Genet Metab. 2012 Jun; 106(2):244-7. Ge RL, Simonson TS, Cooksey RC, Tanna U, Qin G, Huff CD, Witherspoon DJ, Xing J, Zhengzhong B, Prchal JT, Jorde LB, McClain DA. PMID: 22503288; PMCID: PMC3437309.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    51. Genetic determinants of Tibetan high-altitude adaptation. Hum Genet. 2012 Apr; 131(4):527-33. Simonson TS, McClain DA, Jorde LB, Prchal JT. PMID: 22068265.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    52. Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol. 2012 Jan; 29(1):101-11. Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, Simonson TS, Jorde LB, Guthery SL. PMID: 21816865; PMCID: PMC3245542.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    53. Signatures of the preagricultural peopling processes in sub-Saharan Africa as revealed by the phylogeography of early Y chromosome lineages. Mol Biol Evol. 2011 Sep; 28(9):2603-13. Batini C, Ferri G, Destro-Bisol G, Brisighelli F, Luiselli D, Sánchez-Diz P, Rocha J, Simonson T, Brehm A, Montano V, Elwali NE, Spedini G, D'Amato ME, Myres N, Ebbesen P, Comas D, Capelli C. PMID: 21478374.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    54. Maximum-likelihood estimation of recent shared ancestry (ERSA). Genome Res. 2011 May; 21(5):768-74. Huff CD, Witherspoon DJ, Simonson TS, Xing J, Watkins WS, Zhang Y, Tuohy TM, Neklason DW, Burt RW, Guthery SL, Woodward SR, Jorde LB. PMID: 21324875; PMCID: PMC3083094.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    55. Ancestry of the Iban is predominantly Southeast Asian: genetic evidence from autosomal, mitochondrial, and Y chromosomes. PLoS One. 2011 Jan 31; 6(1):e16338. Simonson TS, Xing J, Barrett R, Jerah E, Loa P, Zhang Y, Watkins WS, Witherspoon DJ, Huff CD, Woodward S, Mowry B, Jorde LB. PMID: 21305013; PMCID: PMC3031551.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    56. Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping. Genomics. 2010 Oct; 96(4):199-210. Xing J, Watkins WS, Shlien A, Walker E, Huff CD, Witherspoon DJ, Zhang Y, Simonson TS, Weiss RB, Schiffman JD, Malkin D, Woodward SR, Jorde LB. PMID: 20643205; PMCID: PMC2945611.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    57. Genetic evidence for high-altitude adaptation in Tibet. Science. 2010 Jul 02; 329(5987):72-5. Simonson TS, Yang Y, Huff CD, Yun H, Qin G, Witherspoon DJ, Bai Z, Lorenzo FR, Xing J, Jorde LB, Prchal JT, Ge R. PMID: 20466884.
      View in: PubMed   Mentions: 540     Fields:    Translation:HumansCells
    58. Limited distribution of a cardiomyopathy-associated variant in India. Ann Hum Genet. 2010 Mar; 74(2):184-8. Simonson TS, Zhang Y, Huff CD, Xing J, Watkins WS, Witherspoon DJ, Woodward SR, Jorde LB. PMID: 20201939; PMCID: PMC2901538.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family. Blood Cells Mol Dis. 2009 Nov-Dec; 43(3):221-5. Lorenzo VF, Yang Y, Simonson TS, Nussenzveig R, Jorde LB, Prchal JT, Ge RL. PMID: 19481479; PMCID: PMC3506116.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
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