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Pam Taub

Title(s)Associate Clinical Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0902
La Jolla CA 92093
Phone760-634-8273
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    Pam R. Taub, MD, FACC, FASPC is an Associate Professor at the UC San Diego School of Medicine in the Department of Cardiovascular Medicine. She is the Founding Director of the Step Family Foundation Cardiac Rehabilitation and Wellness Center. Dr. Taub was responsible for all aspects of creating the center.

    Her clinical practice focuses on preventive cardiology and lipidology, as well as women's cardiovascular health. She has extensive clinical trial experience and is active in clinical and translational research. Her research focuses on assessing the impact of behavioral, technological, and pharmacological interventions on cardiometabolic disease. Dr. Taub's is a federally funded researcher with funding from: the National Institutes of Health (Principal Investigator on R01 grant), Department of Defense, Department of Homeland Security and American Heart Association.

    She is currently conducting research studies evaluating:
    • the impact of daily fasting in improving cardiometabolic parameters and
    on mitochondrial function,
    • biomarkers for cardiovascular risk factor stratification,
    • wearable/mobile devices in improving cardiovascular outcomes,
    • epicatechin (compound in dark chocolate) on mitochondrial
    function/cellular bioenergetics and exercise capacity.

    Dr. Taub is widely published and has authored numerous publications in top peer-reviewed journals including Cell Metabolism, Journal of the American Medical Association, and Journal of the American College of Cardiology.

    Dr. Taub holds multiple leadership positions in professional societies, serving as a fellow and board member for the American Society of Preventive Cardiology. She is a fellow and member of the American College of Cardiology Prevention of CV Disease Section Leadership Council. She also serves on American Heart Association Council on Clinical Cardiology (Women in Cardiology Committee).

    Dr. Taub received her MD from Boston University School of Medicine. She completed her residency in internal medicine at the University of Washington Medical Center in Seattle and her fellowship in cardiovascular medicine at UC San Diego. She is board certified in internal medicine, cardiovascular disease.

    Collapse Research 
    Collapse Research Activities and Funding
    Impact of time-restricted feeding (TRF) on glucose homeostasis and mitochondrial function in patients with metabolic syndrome
    NIH/NIDDK R01DK118278Sep 15, 2018 - Jun 30, 2023
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cardiac Rehab for Functional Improvement. Curr Heart Fail Rep. 2020 Jun 08. Epstein E, Rosander A, Pazargadi A, Taub P. PMID: 32514659.
      View in: PubMed   Mentions:    Fields:    
    2. Is Belonging to a Religious Organization Enough? Differences in Religious Affiliation Versus Self-ratings of Spirituality on Behavioral and Psychological Variables in Individuals with Heart Failure. Healthcare (Basel). 2020 May 08; 8(2). Saiz J, Pung MA, Wilson KL, Pruitt C, Rutledge T, Redwine L, Taub PR, Greenberg BH, Mills PJ. PMID: 32397220.
      View in: PubMed   Mentions:
    3. Intermittent Fasting: A Heart Healthy Dietary Pattern? Am J Med. 2020 Apr 21. Dong TA, Sandesara PB, Dhindsa DS, Mehta A, Arneson LC, Dollar AL, Taub PR, Sperling LS. PMID: 32330491.
      View in: PubMed   Mentions:    Fields:    
    4. Enhanced Inflammation is a Marker for Risk of Post-Infarct Ventricular Dysfunction and Heart Failure. Int J Mol Sci. 2020 Jan 26; 21(3). Swiatkiewicz I, Magielski P, Kubica J, Zadourian A, DeMaria AN, Taub PR. PMID: 31991903.
      View in: PubMed   Mentions:    Fields:    
    5. Short-term prognostic implications of serum and urine neutrophil gelatinase-associated lipocalin in acute heart failure: findings from the AKINESIS study. Eur J Heart Fail. 2020 Feb; 22(2):251-263. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A, Murray PT. PMID: 31863682.
      View in: PubMed   Mentions:    Fields:    
    6. Heart Failure and Diabetes Mellitus: Defining the Problem and Exploring the Interrelationship. Am J Cardiol. 2019 12 15; 124 Suppl 1:S3-S11. Wilkinson MJ, Zadourian A, Taub PR. PMID: 31741438.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome. Cell Metab. 2020 Jan 07; 31(1):92-104.e5. Wilkinson MJ, Manoogian ENC, Zadourian A, Lo H, Fakhouri S, Shoghi A, Wang X, Fleischer JG, Navlakha S, Panda S, Taub PR. PMID: 31813824.
      View in: PubMed   Mentions: 6     Fields:    
    8. B-type natriuretic peptide trend predicts clinical significance of worsening renal function in acute heart failure. Eur J Heart Fail. 2019 12; 21(12):1553-1560. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT, Maisel A. PMID: 31769140.
      View in: PubMed   Mentions:    Fields:    
    9. Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary Findings of the Urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic Heart Failure Study (AKINESIS). J Card Fail. 2019 Aug; 25(8):654-665. Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, NuÑez J, Briguori C, Passino C, Maisel A. PMID: 31128242.
      View in: PubMed   Mentions: 1     Fields:    
    10. Tofacitinib Treatment Is Associated With Modest and Reversible Increases in Serum Lipids in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2020 Jan; 18(1):123-132.e3. Sands BE, Taub PR, Armuzzi A, Friedman GS, Moscariello M, Lawendy N, Pedersen RD, Chan G, Nduaka CI, Quirk D, Salese L, Su C, Feagan BG. PMID: 31077827.
      View in: PubMed   Mentions: 4     Fields:    
    11. Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus. Clin Cardiol. 2019 Jun; 42(6):637-643. Mills PJ, Taub PR, Lunde O, Pung MA, Wilson K, Pruitt C, Rutledge T, Maisel A, Greenberg BH. PMID: 31017303.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors. J Am Coll Nutr. 2019 08; 38(6):485-492. Modestino AE, Skowronski EA, Pruitt C, Taub PR, Herbst K, Schmid-Schönbein GW, Heller MJ, Mills PJ. PMID: 30964398.
      View in: PubMed   Mentions:    Fields:    
    13. Intensive Cardiac Rehabilitation: an Underutilized Resource. Curr Cardiol Rep. 2019 03 04; 21(4):19. Freeman AM, Taub PR, Lo HC, Ornish D. PMID: 30828747.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    14. Correction to: Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2018 12; 61(12):2674. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. PMID: 30324489.
      View in: PubMed   Mentions:    Fields:    
    15. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends Pharmacol Sci. 2018 09; 39(9):812-827. Sulli G, Manoogian ENC, Taub PR, Panda S. PMID: 30060890.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    16. Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management. Drugs. 2018 Jul; 78(10):983-994. Zadourian A, Doherty TA, Swiatkiewicz I, Taub PR. PMID: 29943373.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. The usefulness of C-reactive protein for the prediction of post-infarct left ventricular systolic dysfunction and heart failure. Kardiol Pol. 2018; 76(5):821-829. Swiatkiewicz I, Taub PR. PMID: 29633232.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Effect of alirocumab on lipids and lipoproteins in individuals with metabolic syndrome without diabetes: Pooled data from 10 phase 3 trials. Diabetes Obes Metab. 2018 07; 20(7):1632-1641. Henry RR, Müller-Wieland D, Taub PR, Bujas-Bobanovic M, Louie MJ, Letierce A, Ginsberg HN. PMID: 29493859.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. Food Funct. 2018 Jan 24; 9(1):307-319. Moreno-Ulloa A, Nájera-García N, Hernández M, Ramírez-Sánchez I, Taub PR, Su Y, Beltrán-Partida E, Ceballos G, Dugar S, Schreiner G, Best BM, Ciaraldi TP, Henry RR, Villarreal F. PMID: 29171848.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    20. The Deficit of Nutrition Education of Physicians. Am J Med. 2018 04; 131(4):339-345. Aggarwal M, Devries S, Freeman AM, Ostfeld R, Gaggin H, Taub P, Rzeszut AK, Allen K, Conti RC. PMID: 29269228.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2017 10; 60(10):2052-2065. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. PMID: 28770317.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Neutrophil Gelatinase-Associated Lipocalin for Acute Kidney Injury During Acute Heart Failure Hospitalizations: The AKINESIS Study. J Am Coll Cardiol. 2016 09 27; 68(13):1420-1431. Maisel AS, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müller GA, Birkhahn R, Clopton P, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT. PMID: 27659464.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects. Int J Cardiol. 2016 Nov 15; 223:500-506. Gutiérrez-Salmeán G, Meaney E, Lanaspa MA, Cicerchi C, Johnson RJ, Dugar S, Taub P, Ramírez-Sánchez I, Villarreal F, Schreiner G, Ceballos G. PMID: 27552564.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: underlying mechanisms. A double blind, randomized, placebo controlled trial. Food Funct. 2016 Sep 14; 7(9):3686-93. Taub PR, Ramirez-Sanchez I, Patel M, Higginbotham E, Moreno-Ulloa A, Román-Pintos LM, Phillips P, Perkins G, Ceballos G, Villarreal F. PMID: 27491778.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. Cardiovascular Benefits of Dark Chocolate? Curr Treat Options Cardiovasc Med. 2015 Dec; 17(12):54. Higginbotham E, Taub PR. PMID: 26456559.
      View in: PubMed   Mentions:
    26. How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial. J Card Fail. 2016 Apr; 22(4):283-93. Maisel AS, Shah KS, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Iqbal N, Taub PR, Kupfer K, Lee E, Clopton P, Zile M, Greenberg B. PMID: 26433086.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    27. Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 2015 Mar; 6(3):824-33. Barnett CF, Moreno-Ulloa A, Shiva S, Ramirez-Sanchez I, Taub PR, Su Y, Ceballos G, Dugar S, Schreiner G, Villarreal F. PMID: 25598082.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsCTClinical Trials
    28. Proenkephalin predicts acute kidney injury in cardiac surgery patients. Clin Nephrol. 2015 Jan; 83(1):29-35. Shah KS, Taub P, Patel M, Rehfeldt M, Struck J, Clopton P, Mehta RL, Maisel AS. PMID: 25512100.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur J Pharmacol. 2014 Dec 05; 744:76-82. Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub P, Villarreal F, Ceballos G. PMID: 25281837.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    30. Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections. Respirology. 2014 Apr; 19(3):382-8. Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L. PMID: 24460728.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem. 2014 Jan; 25(1):91-4. Gutierrez-Salmean G, Ciaraldi TP, Nogueira L, Barboza J, Taub PR, Hogan MC, Henry RR, Meaney E, Villarreal F, Ceballos G, Ramirez-Sanchez I. PMID: 24314870.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    32. Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: restorative effects of (-)-epicatechin-rich cocoa. Clin Sci (Lond). 2013 Oct; 125(8):383-9. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. PMID: 23642227.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    33. Mid-region pro-adrenomedullin adds predictive value to clinical predictors and Framingham risk score for long-term mortality in stable outpatients with heart failure. Eur J Heart Fail. 2013 Dec; 15(12):1343-9. Xue Y, Taub P, Iqbal N, Fard A, Clopton P, Maisel A. PMID: 23887059.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol. 2013 Oct 09; 168(4):3982-3990. Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. PMID: 23870648.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCTClinical Trials
    35. Primary results of the HABIT Trial (heart failure assessment with BNP in the home). J Am Coll Cardiol. 2013 Apr 23; 61(16):1726-35. Maisel A, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Borden K, Iqbal N, Taub PR, Kupfer K, Clopton P, Greenberg B. PMID: 23500322.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    36. Beneficial and detrimental effects of glycemic control on cardiovascular disease in type 2 diabetes. Curr Cardiol Rep. 2013 Feb; 15(2):332. Taub PR, Higginbotham E, Henry RR. PMID: 23314689.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Post-traumatic stress disorder: a fast track to premature cardiovascular disease? Cardiol Rev. 2013 Jan-Feb; 21(1):16-22. Wentworth BA, Stein MB, Redwine LS, Xue Y, Taub PR, Clopton P, Nayak KR, Maisel AS. PMID: 22717656.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    38. Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jan 15; 913-914:161-8. Prasain JK, Arabshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. PMID: 23314354.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    39. Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis: additive effects with exercise. J Cardiovasc Pharmacol. 2012 Nov; 60(5):429-38. Ramirez-Sanchez I, Nogueira L, Moreno A, Murphy A, Taub P, Perkins G, Ceballos GM, Hogan M, Malek M, Villarreal F. PMID: 22833114.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    40. Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with cardiorenal syndrome. Expert Rev Cardiovasc Ther. 2012 May; 10(5):657-67. Taub PR, Borden KC, Fard A, Maisel A. PMID: 22651841.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. Cardiac biomarkers, mortality, and post-traumatic stress disorder in military veterans. Am J Cardiol. 2012 Apr 15; 109(8):1215-8. Xue Y, Taub PR, Iqbal N, Fard A, Wentworth B, Redwine L, Clopton P, Stein M, Maisel A. PMID: 22305506.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    42. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy AN, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. PMID: 22376256.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    43. Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2011 Aug; 15(1):13-8. Taub PR, Fields JD, Wu AH, Miss JC, Lawton MT, Smith WS, Young WL, Zaroff JG, Ko NU. PMID: 21479679.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15; 589(Pt 18):4615-31. Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. PMID: 21788351.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    45. Hypervolemic and optivolemic natriuretic peptides in acute heart failure. Contrib Nephrol. 2011; 171:74-79. Xue Y, Taub PR, Fard A, Maisel AS. PMID: 21625093.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Biomarkers of heart failure. Congest Heart Fail. 2010 Jul; 16 Suppl 1:S19-24. Taub PR, Gabbai-Saldate P, Maisel A. PMID: 20653707.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    47. Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J Am Coll Cardiol. 2010 Jun 22; 55(25):2869-76. Yamazaki KG, Taub PR, Barraza-Hidalgo M, Rivas MM, Zambon AC, Ceballos G, Villarreal FJ. PMID: 20579545.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    48. Hemifacial lipomatosis, a possible subtype of partial hemifacial hyperplasia: CT and MR imaging findings. AJNR Am J Neuroradiol. 2010 May; 31(5):891-3. Bou-Haidar P, Taub P, Som P. PMID: 19926700.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. Usefulness of B-type natriuretic peptide levels in predicting hemodynamic and clinical decompensation. Heart Fail Clin. 2009 Apr; 5(2):169-75. Taub PR, Daniels LB, Maisel AS. PMID: 19249686.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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