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Pam Taub

Title(s)Associate Clinical Professor, Medicine
SchoolHealth Sciences
Phone760-634-8273
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    Collapse Overview 
    Collapse Overview
    Pam R. Taub, MD, FACC, FASPC is an Associate Professor at the UC San Diego School of Medicine in the Department of Cardiovascular Medicine. She is the Founding Director of the Step Family Foundation Cardiac Rehabilitation and Wellness Center. Dr. Taub was responsible for all aspects of creating the center.

    Her clinical practice focuses on preventive cardiology and lipidology, as well as women's cardiovascular health. She has extensive clinical trial experience and is active in clinical and translational research. Her research focuses on assessing the impact of behavioral, technological, and pharmacological interventions on cardiometabolic disease. Dr. Taub's is a federally funded researcher with funding from: the National Institutes of Health (Principal Investigator on R01 grant), Department of Defense, Department of Homeland Security and American Heart Association.

    She is currently conducting research studies evaluating:
    • the impact of daily fasting in improving cardiometabolic parameters and
    on mitochondrial function,
    • biomarkers for cardiovascular risk factor stratification,
    • wearable/mobile devices in improving cardiovascular outcomes,
    • epicatechin (compound in dark chocolate) on mitochondrial
    function/cellular bioenergetics and exercise capacity.

    Dr. Taub is widely published and has authored numerous publications in top peer-reviewed journals including Cell Metabolism, Journal of the American Medical Association, and Journal of the American College of Cardiology.

    Dr. Taub holds multiple leadership positions in professional societies, serving as a fellow and board member for the American Society of Preventive Cardiology. She is a fellow and member of the American College of Cardiology Prevention of CV Disease Section Leadership Council. She also serves on American Heart Association Council on Clinical Cardiology (Women in Cardiology Committee).

    Dr. Taub received her MD from Boston University School of Medicine. She completed her residency in internal medicine at the University of Washington Medical Center in Seattle and her fellowship in cardiovascular medicine at UC San Diego. She is board certified in internal medicine, cardiovascular disease.

    Collapse Research 
    Collapse Research Activities and Funding
    Impact of time-restricted feeding (TRF) on glucose homeostasis and mitochondrial function in patients with metabolic syndrome
    NIH/NIDDK R01DK118278Sep 15, 2018 - Jun 30, 2023
    Role: Principal Investigator

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    Collapse Clinical Trials
    Collapse Featured Publications
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Swiatkiewicz I, Magielski P, Kubica J, Zadourian A, DeMaria AN, Taub PR. Enhanced Inflammation is a Marker for Risk of Post-Infarct Ventricular Dysfunction and Heart Failure. Int J Mol Sci. 2020 Jan 26; 21(3). PMID: 31991903.
      View in: PubMed
    2. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A, Murray PT. Short-term prognostic implications of serum and urine neutrophil gelatinase-associated lipocalin in acute heart failure: findings from the AKINESIS study. Eur J Heart Fail. 2020 Feb; 22(2):251-263. PMID: 31863682.
      View in: PubMed
    3. Wilkinson MJ, Zadourian A, Taub PR. Heart Failure and Diabetes Mellitus: Defining the Problem and Exploring the Interrelationship. Am J Cardiol. 2019 Dec 15; 124 Suppl 1:S3-S11. PMID: 31741438.
      View in: PubMed
    4. Wilkinson MJ, Manoogian ENC, Zadourian A, Lo H, Fakhouri S, Shoghi A, Wang X, Fleischer JG, Navlakha S, Panda S, Taub PR. Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome. Cell Metab. 2020 Jan 07; 31(1):92-104.e5. PMID: 31813824.
      View in: PubMed
    5. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT, Maisel A. B-type natriuretic peptide trend predicts clinical significance of worsening renal function in acute heart failure. Eur J Heart Fail. 2019 Dec; 21(12):1553-1560. PMID: 31769140.
      View in: PubMed
    6. Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, NuÑez J, Briguori C, Passino C, Maisel A. Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary Findings of the Urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic Heart Failure Study (AKINESIS). J Card Fail. 2019 Aug; 25(8):654-665. PMID: 31128242.
      View in: PubMed
    7. Sands BE, Taub PR, Armuzzi A, Friedman GS, Moscariello M, Lawendy N, Pedersen RD, Chan G, Nduaka CI, Quirk D, Salese L, Su C, Feagan BG. Tofacitinib Treatment Is Associated With Modest and Reversible Increases in Serum Lipids in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2020 Jan; 18(1):123-132.e3. PMID: 31077827.
      View in: PubMed
    8. Mills PJ, Taub PR, Lunde O, Pung MA, Wilson K, Pruitt C, Rutledge T, Maisel A, Greenberg BH. Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus. Clin Cardiol. 2019 Jun; 42(6):637-643. PMID: 31017303.
      View in: PubMed
    9. Modestino AE, Skowronski EA, Pruitt C, Taub PR, Herbst K, Schmid-Schönbein GW, Heller MJ, Mills PJ. Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors. J Am Coll Nutr. 2019 Aug; 38(6):485-492. PMID: 30964398.
      View in: PubMed
    10. Freeman AM, Taub PR, Lo HC, Ornish D. Intensive Cardiac Rehabilitation: an Underutilized Resource. Curr Cardiol Rep. 2019 03 04; 21(4):19. PMID: 30828747.
      View in: PubMed
    11. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Correction to: Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2018 12; 61(12):2674. PMID: 30324489.
      View in: PubMed
    12. Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends Pharmacol Sci. 2018 09; 39(9):812-827. PMID: 30060890.
      View in: PubMed
    13. Zadourian A, Doherty TA, Swiatkiewicz I, Taub PR. Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management. Drugs. 2018 Jul; 78(10):983-994. PMID: 29943373.
      View in: PubMed
    14. Swiatkiewicz I, Taub PR. The usefulness of C-reactive protein for the prediction of post-infarct left ventricular systolic dysfunction and heart failure. Kardiol Pol. 2018; 76(5):821-829. PMID: 29633232.
      View in: PubMed
    15. Henry RR, Müller-Wieland D, Taub PR, Bujas-Bobanovic M, Louie MJ, Letierce A, Ginsberg HN. Effect of alirocumab on lipids and lipoproteins in individuals with metabolic syndrome without diabetes: Pooled data from 10 phase 3 trials. Diabetes Obes Metab. 2018 07; 20(7):1632-1641. PMID: 29493859.
      View in: PubMed
    16. Moreno-Ulloa A, Nájera-García N, Hernández M, Ramírez-Sánchez I, Taub PR, Su Y, Beltrán-Partida E, Ceballos G, Dugar S, Schreiner G, Best BM, Ciaraldi TP, Henry RR, Villarreal F. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. Food Funct. 2018 Jan 24; 9(1):307-319. PMID: 29171848.
      View in: PubMed
    17. Aggarwal M, Devries S, Freeman AM, Ostfeld R, Gaggin H, Taub P, Rzeszut AK, Allen K, Conti RC. The Deficit of Nutrition Education of Physicians. Am J Med. 2018 04; 131(4):339-345. PMID: 29269228.
      View in: PubMed
    18. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2017 10; 60(10):2052-2065. PMID: 28770317.
      View in: PubMed
    19. Maisel AS, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müller GA, Birkhahn R, Clopton P, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT. Neutrophil Gelatinase-Associated Lipocalin for Acute Kidney Injury During Acute Heart Failure Hospitalizations: The AKINESIS Study. J Am Coll Cardiol. 2016 09 27; 68(13):1420-1431. PMID: 27659464.
      View in: PubMed
    20. Gutiérrez-Salmeán G, Meaney E, Lanaspa MA, Cicerchi C, Johnson RJ, Dugar S, Taub P, Ramírez-Sánchez I, Villarreal F, Schreiner G, Ceballos G. A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects. Int J Cardiol. 2016 Nov 15; 223:500-506. PMID: 27552564.
      View in: PubMed
    21. Taub PR, Ramirez-Sanchez I, Patel M, Higginbotham E, Moreno-Ulloa A, Román-Pintos LM, Phillips P, Perkins G, Ceballos G, Villarreal F. Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: underlying mechanisms. A double blind, randomized, placebo controlled trial. Food Funct. 2016 Sep 14; 7(9):3686-93. PMID: 27491778.
      View in: PubMed
    22. Higginbotham E, Taub PR. Cardiovascular Benefits of Dark Chocolate? Curr Treat Options Cardiovasc Med. 2015 Dec; 17(12):54. PMID: 26456559.
      View in: PubMed
    23. Maisel AS, Shah KS, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Iqbal N, Taub PR, Kupfer K, Lee E, Clopton P, Zile M, Greenberg B. How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial. J Card Fail. 2016 Apr; 22(4):283-93. PMID: 26433086.
      View in: PubMed
    24. Barnett CF, Moreno-Ulloa A, Shiva S, Ramirez-Sanchez I, Taub PR, Su Y, Ceballos G, Dugar S, Schreiner G, Villarreal F. Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 2015 Mar; 6(3):824-33. PMID: 25598082.
      View in: PubMed
    25. Shah KS, Taub P, Patel M, Rehfeldt M, Struck J, Clopton P, Mehta RL, Maisel AS. Proenkephalin predicts acute kidney injury in cardiac surgery patients. Clin Nephrol. 2015 Jan; 83(1):29-35. PMID: 25512100.
      View in: PubMed
    26. Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub P, Villarreal F, Ceballos G. Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur J Pharmacol. 2014 Dec 05; 744:76-82. PMID: 25281837.
      View in: PubMed
    27. Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L. Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections. Respirology. 2014 Apr; 19(3):382-8. PMID: 24460728.
      View in: PubMed
    28. Gutierrez-Salmean G, Ciaraldi TP, Nogueira L, Barboza J, Taub PR, Hogan MC, Henry RR, Meaney E, Villarreal F, Ceballos G, Ramirez-Sanchez I. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem. 2014 Jan; 25(1):91-4. PMID: 24314870.
      View in: PubMed
    29. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: restorative effects of (-)-epicatechin-rich cocoa. Clin Sci (Lond). 2013 Oct; 125(8):383-9. PMID: 23642227.
      View in: PubMed
    30. Xue Y, Taub P, Iqbal N, Fard A, Clopton P, Maisel A. Mid-region pro-adrenomedullin adds predictive value to clinical predictors and Framingham risk score for long-term mortality in stable outpatients with heart failure. Eur J Heart Fail. 2013 Dec; 15(12):1343-9. PMID: 23887059.
      View in: PubMed
    31. Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol. 2013 Oct 09; 168(4):3982-3990. PMID: 23870648.
      View in: PubMed
    32. Maisel A, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Borden K, Iqbal N, Taub PR, Kupfer K, Clopton P, Greenberg B. Primary results of the HABIT Trial (heart failure assessment with BNP in the home). J Am Coll Cardiol. 2013 Apr 23; 61(16):1726-35. PMID: 23500322.
      View in: PubMed
    33. Taub PR, Higginbotham E, Henry RR. Beneficial and detrimental effects of glycemic control on cardiovascular disease in type 2 diabetes. Curr Cardiol Rep. 2013 Feb; 15(2):332. PMID: 23314689.
      View in: PubMed
    34. Wentworth BA, Stein MB, Redwine LS, Xue Y, Taub PR, Clopton P, Nayak KR, Maisel AS. Post-traumatic stress disorder: a fast track to premature cardiovascular disease? Cardiol Rev. 2013 Jan-Feb; 21(1):16-22. PMID: 22717656.
      View in: PubMed
    35. Prasain JK, Arabshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jan 15; 913-914:161-8. PMID: 23314354.
      View in: PubMed
    36. Ramirez-Sanchez I, Nogueira L, Moreno A, Murphy A, Taub P, Perkins G, Ceballos GM, Hogan M, Malek M, Villarreal F. Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis: additive effects with exercise. J Cardiovasc Pharmacol. 2012 Nov; 60(5):429-38. PMID: 22833114.
      View in: PubMed
    37. Taub PR, Borden KC, Fard A, Maisel A. Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with cardiorenal syndrome. Expert Rev Cardiovasc Ther. 2012 May; 10(5):657-67. PMID: 22651841.
      View in: PubMed
    38. Xue Y, Taub PR, Iqbal N, Fard A, Wentworth B, Redwine L, Clopton P, Stein M, Maisel A. Cardiac biomarkers, mortality, and post-traumatic stress disorder in military veterans. Am J Cardiol. 2012 Apr 15; 109(8):1215-8. PMID: 22305506.
      View in: PubMed
    39. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy AN, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. PMID: 22376256.
      View in: PubMed
    40. Taub PR, Fields JD, Wu AH, Miss JC, Lawton MT, Smith WS, Young WL, Zaroff JG, Ko NU. Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2011 Aug; 15(1):13-8. PMID: 21479679.
      View in: PubMed
    41. Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15; 589(Pt 18):4615-31. PMID: 21788351.
      View in: PubMed
    42. Xue Y, Taub PR, Fard A, Maisel AS. Hypervolemic and optivolemic natriuretic peptides in acute heart failure. Contrib Nephrol. 2011; 171:74-79. PMID: 21625093.
      View in: PubMed
    43. Taub PR, Gabbai-Saldate P, Maisel A. Biomarkers of heart failure. Congest Heart Fail. 2010 Jul; 16 Suppl 1:S19-24. PMID: 20653707.
      View in: PubMed
    44. Yamazaki KG, Taub PR, Barraza-Hidalgo M, Rivas MM, Zambon AC, Ceballos G, Villarreal FJ. Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J Am Coll Cardiol. 2010 Jun 22; 55(25):2869-76. PMID: 20579545.
      View in: PubMed
    45. Bou-Haidar P, Taub P, Som P. Hemifacial lipomatosis, a possible subtype of partial hemifacial hyperplasia: CT and MR imaging findings. AJNR Am J Neuroradiol. 2010 May; 31(5):891-3. PMID: 19926700.
      View in: PubMed
    46. Taub PR, Daniels LB, Maisel AS. Usefulness of B-type natriuretic peptide levels in predicting hemodynamic and clinical decompensation. Heart Fail Clin. 2009 Apr; 5(2):169-75. PMID: 19249686.
      View in: PubMed