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Pam Taub

Title(s)Associate Clinical Professor, Medicine
SchoolHealth Sciences
Phone760-634-8273
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    Collapse Overview 
    Collapse Overview
    Dr. Taub is a general cardiologist and assistant professor of medicine at the UC San Diego Health System. She is the director of the Hannah and Gene Step Cardiac Wellness and Rehabilitation Center that will be located in the new UC San Diego Jacobs Medical Center opening in 2016.

    The mission of the Center is to actively engage patients and the community in prevention of cardiovascular disease. In addition to having a comprehensive cardiac rehabilitation program for patients with established cardiac disease, the Center will provide evidence-based therapies and classes that will focus on disease prevention. The Center will be conducting research on biomarkers and other diagnostics, wearable/mobile technologies and various therapies that can improve patient outcomes.

    Dr. Taub's clinical practice focuses on preventive cardiology. She believes prevention is the “new frontier” in cardiovascular medicine. She takes an evidence-based approach to care that is tailored to the individual patient, with the goal of minimizing medications and procedures. She also actively collaborates with other specialists in providing cardiac care for the complex patient with multi-system disease.

    She is active in clinical/translational research and has received funding from the National Institutes of Health, American College of Cardiology and American Heart Association.

    Collapse Research 
    Collapse Research Activities and Funding
    Impact of time-restricted feeding (TRF) on glucose homeostasis and mitochondrial function in patients with metabolic syndrome
    NIH/NIDDK R01DK118278Sep 15, 2018 - Jun 30, 2023
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, NuÑez J, Briguori C, Passino C, Maisel A. Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary Findings of the Urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic Heart Failure Study (AKINESIS). J Card Fail. 2019 May 22. PMID: 31128242.
      View in: PubMed
    2. Sands BE, Taub PR, Armuzzi A, Friedman GS, Moscariello M, Lawendy N, Pedersen RD, Chan G, Nduaka CI, Quirk D, Salese L, Su C, Feagan BG. Tofacitinib Treatment Is Associated With Modest and Reversible Increases in Serum Lipids in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2019 May 08. PMID: 31077827.
      View in: PubMed
    3. Mills PJ, Taub PR, Lunde O, Pung MA, Wilson K, Pruitt C, Rutledge T, Maisel A, Greenberg BH. Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus. Clin Cardiol. 2019 Jun; 42(6):637-643. PMID: 31017303.
      View in: PubMed
    4. Modestino AE, Skowronski EA, Pruitt C, Taub PR, Herbst K, Schmid-Schönbein GW, Heller MJ, Mills PJ. Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors. J Am Coll Nutr. 2019 Apr 09; 1-8. PMID: 30964398.
      View in: PubMed
    5. Freeman AM, Taub PR, Lo HC, Ornish D. Intensive Cardiac Rehabilitation: an Underutilized Resource. Curr Cardiol Rep. 2019 Mar 04; 21(4):19. PMID: 30828747.
      View in: PubMed
    6. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Correction to: Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2018 12; 61(12):2674. PMID: 30324489.
      View in: PubMed
    7. Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends Pharmacol Sci. 2018 09; 39(9):812-827. PMID: 30060890.
      View in: PubMed
    8. Zadourian A, Doherty TA, Swiatkiewicz I, Taub PR. Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management. Drugs. 2018 Jul; 78(10):983-994. PMID: 29943373.
      View in: PubMed
    9. Swiatkiewicz I, Taub PR. The usefulness of C-reactive protein for the prediction of post-infarct left ventricular systolic dysfunction and heart failure. Kardiol Pol. 2018; 76(5):821-829. PMID: 29633232.
      View in: PubMed
    10. Henry RR, Müller-Wieland D, Taub PR, Bujas-Bobanovic M, Louie MJ, Letierce A, Ginsberg HN. Effect of alirocumab on lipids and lipoproteins in individuals with metabolic syndrome without diabetes: Pooled data from 10 phase 3 trials. Diabetes Obes Metab. 2018 07; 20(7):1632-1641. PMID: 29493859.
      View in: PubMed
    11. Moreno-Ulloa A, Nájera-García N, Hernández M, Ramírez-Sánchez I, Taub PR, Su Y, Beltrán-Partida E, Ceballos G, Dugar S, Schreiner G, Best BM, Ciaraldi TP, Henry RR, Villarreal F. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. Food Funct. 2018 Jan 24; 9(1):307-319. PMID: 29171848.
      View in: PubMed
    12. Aggarwal M, Devries S, Freeman AM, Ostfeld R, Gaggin H, Taub P, Rzeszut AK, Allen K, Conti RC. The Deficit of Nutrition Education of Physicians. Am J Med. 2018 Apr; 131(4):339-345. PMID: 29269228.
      View in: PubMed
    13. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2017 10; 60(10):2052-2065. PMID: 28770317.
      View in: PubMed
    14. Maisel AS, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müller GA, Birkhahn R, Clopton P, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT. Neutrophil Gelatinase-Associated Lipocalin for Acute Kidney Injury During Acute Heart Failure Hospitalizations: The AKINESIS Study. J Am Coll Cardiol. 2016 09 27; 68(13):1420-1431. PMID: 27659464.
      View in: PubMed
    15. Gutiérrez-Salmeán G, Meaney E, Lanaspa MA, Cicerchi C, Johnson RJ, Dugar S, Taub P, Ramírez-Sánchez I, Villarreal F, Schreiner G, Ceballos G. A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects. Int J Cardiol. 2016 Nov 15; 223:500-506. PMID: 27552564.
      View in: PubMed
    16. Taub PR, Ramirez-Sanchez I, Patel M, Higginbotham E, Moreno-Ulloa A, Román-Pintos LM, Phillips P, Perkins G, Ceballos G, Villarreal F. Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: underlying mechanisms. A double blind, randomized, placebo controlled trial. Food Funct. 2016 Sep 14; 7(9):3686-93. PMID: 27491778; PMCID: PMC5025384 [Available on 09/14/17].
    17. Higginbotham E, Taub PR. Cardiovascular Benefits of Dark Chocolate? Curr Treat Options Cardiovasc Med. 2015 Dec; 17(12):54. PMID: 26456559.
      View in: PubMed
    18. Maisel AS, Shah KS, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Iqbal N, Taub PR, Kupfer K, Lee E, Clopton P, Zile M, Greenberg B. How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial. J Card Fail. 2016 Apr; 22(4):283-93. PMID: 26433086.
      View in: PubMed
    19. Barnett CF, Moreno-Ulloa A, Shiva S, Ramirez-Sanchez I, Taub PR, Su Y, Ceballos G, Dugar S, Schreiner G, Villarreal F. Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 2015 Mar; 6(3):824-33. PMID: 25598082; PMCID: PMC4357542.
    20. Shah KS, Taub P, Patel M, Rehfeldt M, Struck J, Clopton P, Mehta RL, Maisel AS. Proenkephalin predicts acute kidney injury in cardiac surgery patients. Clin Nephrol. 2015 Jan; 83(1):29-35. PMID: 25512100.
      View in: PubMed
    21. Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub P, Villarreal F, Ceballos G. Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur J Pharmacol. 2014 Dec 05; 744:76-82. PMID: 25281837.
      View in: PubMed
    22. Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L. Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections. Respirology. 2014 Apr; 19(3):382-8. PMID: 24460728; PMCID: PMC4276722.
    23. Gutierrez-Salmean G, Ciaraldi TP, Nogueira L, Barboza J, Taub PR, Hogan MC, Henry RR, Meaney E, Villarreal F, Ceballos G, Ramirez-Sanchez I. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem. 2014 Jan; 25(1):91-4. PMID: 24314870.
      View in: PubMed
    24. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: restorative effects of (-)-epicatechin-rich cocoa. Clin Sci (Lond). 2013 Oct; 125(8):383-9. PMID: 23642227.
      View in: PubMed
    25. Xue Y, Taub P, Iqbal N, Fard A, Clopton P, Maisel A. Mid-region pro-adrenomedullin adds predictive value to clinical predictors and Framingham risk score for long-term mortality in stable outpatients with heart failure. Eur J Heart Fail. 2013 Dec; 15(12):1343-9. PMID: 23887059.
      View in: PubMed
    26. Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol. 2013 Oct 09; 168(4):3982-3990. PMID: 23870648; PMCID: PMC3805662.
    27. Maisel A, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Borden K, Iqbal N, Taub PR, Kupfer K, Clopton P, Greenberg B. Primary results of the HABIT Trial (heart failure assessment with BNP in the home). J Am Coll Cardiol. 2013 Apr 23; 61(16):1726-35. PMID: 23500322.
      View in: PubMed
    28. Taub PR, Higginbotham E, Henry RR. Beneficial and detrimental effects of glycemic control on cardiovascular disease in type 2 diabetes. Curr Cardiol Rep. 2013 Feb; 15(2):332. PMID: 23314689.
      View in: PubMed
    29. Wentworth BA, Stein MB, Redwine LS, Xue Y, Taub PR, Clopton P, Nayak KR, Maisel AS. Post-traumatic stress disorder: a fast track to premature cardiovascular disease? Cardiol Rev. 2013 Jan-Feb; 21(1):16-22. PMID: 22717656.
      View in: PubMed
    30. Prasain JK, Arabshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jan 15; 913-914:161-8. PMID: 23314354; PMCID: PMC3779072.
    31. Ramirez-Sanchez I, Nogueira L, Moreno A, Murphy A, Taub P, Perkins G, Ceballos GM, Hogan M, Malek M, Villarreal F. Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis: additive effects with exercise. J Cardiovasc Pharmacol. 2012 Nov; 60(5):429-38. PMID: 22833114; PMCID: PMC3496054.
    32. Taub PR, Borden KC, Fard A, Maisel A. Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with cardiorenal syndrome. Expert Rev Cardiovasc Ther. 2012 May; 10(5):657-67. PMID: 22651841; PMCID: PMC4060800.
    33. Xue Y, Taub PR, Iqbal N, Fard A, Wentworth B, Redwine L, Clopton P, Stein M, Maisel A. Cardiac biomarkers, mortality, and post-traumatic stress disorder in military veterans. Am J Cardiol. 2012 Apr 15; 109(8):1215-8. PMID: 22305506.
      View in: PubMed
    34. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy AN, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. PMID: 22376256.
      View in: PubMed
    35. Taub PR, Fields JD, Wu AH, Miss JC, Lawton MT, Smith WS, Young WL, Zaroff JG, Ko NU. Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2011 Aug; 15(1):13-8. PMID: 21479679; PMCID: PMC3133817.
    36. Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15; 589(Pt 18):4615-31. PMID: 21788351; PMCID: PMC3208228.
    37. Xue Y, Taub PR, Fard A, Maisel AS. Hypervolemic and optivolemic natriuretic peptides in acute heart failure. Contrib Nephrol. 2011; 171:74-9. PMID: 21625093.
      View in: PubMed
    38. Taub PR, Gabbai-Saldate P, Maisel A. Biomarkers of heart failure. Congest Heart Fail. 2010 Jul; 16 Suppl 1:S19-24. PMID: 20653707.
      View in: PubMed
    39. Yamazaki KG, Taub PR, Barraza-Hidalgo M, Rivas MM, Zambon AC, Ceballos G, Villarreal FJ. Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J Am Coll Cardiol. 2010 Jun 22; 55(25):2869-76. PMID: 20579545; PMCID: PMC2915587.
    40. Bou-Haidar P, Taub P, Som P. Hemifacial lipomatosis, a possible subtype of partial hemifacial hyperplasia: CT and MR imaging findings. AJNR Am J Neuroradiol. 2010 May; 31(5):891-3. PMID: 19926700.
      View in: PubMed
    41. Taub PR, Daniels LB, Maisel AS. Usefulness of B-type natriuretic peptide levels in predicting hemodynamic and clinical decompensation. Heart Fail Clin. 2009 Apr; 5(2):169-75. PMID: 19249686.
      View in: PubMed