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Alexis Komor

Title(s)Assistant Professor, Chemistry and Biochemistry
SchoolAcademic Aff
Phone858-246-2608
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Davies K, Komor AC, Gaudelli NM. The Beginning of Base Editing: An Interview with Alexis C. Komor and Nicole M. Gaudelli. CRISPR J. 2019 Apr; 2:81-90. PMID: 30998094.
      View in: PubMed
    2. Ranzau BL, Komor AC. Genome, Epigenome, and Transcriptome Editing via Chemical Modification of Nucleobases in Living Cells. Biochemistry. 2019 Feb 05; 58(5):330-335. PMID: 30500171.
      View in: PubMed
    3. Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. 2018 Jul; 559(7714):E8. PMID: 29720650.
      View in: PubMed
    4. Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. 2017 11 23; 551(7681):464-471. PMID: 29160308.
      View in: PubMed
    5. Komor AC, Badran AH, Liu DR. Editing the Genome Without Double-Stranded DNA Breaks. ACS Chem Biol. 2018 02 16; 13(2):383-388. PMID: 28957631.
      View in: PubMed
    6. Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. Sci Adv. 2017 Aug; 3(8):eaao4774. PMID: 28875174.
      View in: PubMed
    7. Rees HA, Komor AC, Yeh WH, Caetano-Lopes J, Warman M, Edge ASB, Liu DR. Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery. Nat Commun. 2017 06 06; 8:15790. PMID: 28585549.
      View in: PubMed
    8. Komor AC, Badran AH, Liu DR. CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes. Cell. 2017 04 20; 169(3):559. PMID: 28431253.
      View in: PubMed
    9. Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions. Nat Biotechnol. 2017 04; 35(4):371-376. PMID: 28191901.
      View in: PubMed
    10. Komor AC, Badran AH, Liu DR. CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes. Cell. 2017 Jan 12; 168(1-2):20-36. PMID: 27866654.
      View in: PubMed
    11. Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature. 2016 05 19; 533(7603):420-4. PMID: 27096365; PMCID: PMC4873371 [Available on 10/20/16].
    12. Komor AC, Barton JK. An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency. J Am Chem Soc. 2014 Oct 08; 136(40):14160-72. PMID: 25254630; PMCID: PMC4195389.
    13. Weidmann AG, Komor AC, Barton JK. Targeted Chemotherapy with Metal Complexes. Comments Mod Chem A Comments Inorg Chem. 2014 May; 34(3-4):114-123. PMID: 25642012.
      View in: PubMed
    14. Bailis JM, Gordon ML, Gurgel JL, Komor AC, Barton JK, Kirsch IR. An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency. PLoS One. 2013; 8(10):e78726. PMID: 24205301.
      View in: PubMed
    15. Weidmann AG, Komor AC, Barton JK. Biological effects of simple changes in functionality on rhodium metalloinsertors. Philos Trans A Math Phys Eng Sci. 2013 Jul 28; 371(1995):20120117. PMID: 23776288.
      View in: PubMed
    16. Komor AC, Barton JK. The path for metal complexes to a DNA target. Chem Commun (Camb). 2013 May 07; 49(35):3617-30. PMID: 23423158.
      View in: PubMed
    17. Komor AC, Schneider CJ, Weidmann AG, Barton JK. Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization. J Am Chem Soc. 2012 Nov 21; 134(46):19223-33. PMID: 23137296; PMCID: PMC3740518.
    18. Ernst RJ, Komor AC, Barton JK. Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells. Biochemistry. 2011 Dec 20; 50(50):10919-28. PMID: 22103240; PMCID: PMC3364161.
    19. Soo HS, Komor AC, Iavarone AT, Chang CJ. A hydrogen-bond facilitated cycle for oxygen reduction by an acid- and base-compatible iron platform. Inorg Chem. 2009 Nov 02; 48(21):10024-35. PMID: 19780564.
      View in: PubMed