Mark Hepokoski

Title(s)	Assistant Professor Of Clinical, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Inpatient use of metformin and acarbose is associated with reduced mortality of COVID-19 patients with type 2 diabetes mellitus. Endocrinol Diabetes Metab. 2021 Sep 29; e00301. Li J, Wei Q, McCowen KC, Xiong W, Liu J, Jiang W, Thomas RL, Hepokoski M, He M, Shyy JYJ, Malhotra A, Xiong N, Li WX. PMID: 34585841.

View in: PubMed Mentions:
The State of Morning Report in the Current Healthcare Landscape: a National Survey of Internal Medicine Program Directors. J Gen Intern Med. 2021 Sep 28. Lessing JN, McGarry K, Schiffman F, Austin M, Hepokoski M, Keniston A, Tammaro D, Finn KM. PMID: 34585310; PMCID: PMC8477724.

View in: PubMed Mentions: Fields:
Int Internal Medicine
Targeting Mitochondria and Metabolism in Acute Kidney Injury. J Clin Med. 2021 Sep 03; 10(17). Li Y, Hepokoski M, Gu W, Simonson T, Singh P. PMID: 34501442; PMCID: PMC8432487.

View in: PubMed Mentions:
Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19. bioRxiv. 2021 Aug 24. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 34462742; PMCID: PMC8404884.

View in: PubMed Mentions:
Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients: a case series and review of the literature. Clin Infect Dis. 2021 May 14. Masso-Silva JA, Moshensky A, Lam MTY, Odish M, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott R, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Alexander LEC. PMID: 33988226; PMCID: PMC8241438.

View in: PubMed Mentions: 2 Fields:
Com Communicable Diseases
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2. Circ Res. 2021 04 30; 128(9):1323-1326. Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. PMID: 33784827; PMCID: PMC8091897.

View in: PubMed Mentions: 27 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals Cells
Inpatient Use of Metformin and Acarbose Is Associated with Reduced Mortality of COVID-19 Patients with Type 2 Diabetes Mellitus. Res Sq. 2021 Mar 26. Li W, Li J, Wei Q, McCowen K, Xiong W, Liu J, Jiang W, Thomas R, Hepokoski M, He M, Shyy J, Malhotra A, Xiong N. PMID: 33791691; PMCID: PMC8010742.

View in: PubMed Mentions:
Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury. Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L821-L831. Hepokoski M, Wang J, Li K, Li Y, Gupta P, Mai T, Moshensky A, Alotaibi M, Crotty Alexander LE, Malhotra A, Singh P. PMID: 33565357; PMCID: PMC8174821.

View in: PubMed Mentions: 3 Fields:
Cel Cell Biology Mol Molecular Biology Phy Physiology Pul Pulmonary Medicine
Translation:Animals Cells
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2. bioRxiv. 2020 Dec 04. Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. PMID: 33300001; PMCID: PMC7724674.

View in: PubMed Mentions: 3
Metformin Use in Diabetes Prior to Hospitalization: Effects on Mortality in Covid-19. Endocr Pract. 2020 Oct; 26(10):1166-1172. Li J, Wei Q, Li WX, McCowen KC, Xiong W, Liu J, Jiang W, Marin T, Thomas RL, He M, Gongol B, Hepokoski M, Yuan JX, Shyy JY, Xiong N, Malhotra A. PMID: 33471718; PMCID: PMC7834011.

View in: PubMed Mentions: 7 Fields:
End Endocrinology
Translation:Humans
ACE2, Metformin, and COVID-19. iScience. 2020 Jul 31; 23(9):101425. Malhotra A, Hepokoski M, McCowen KC, Y-J Shyy J. PMID: 32818905; PMCID: PMC7452173.

View in: PubMed Mentions: 14
Mitochondrial transplantation: respiration rescue in respiratory failure. . 2020 01 01; 318(1):L76-L77. Hepokoski M. PMID: 31774303.

View in: PubMed Mentions: Translation:Animals Cells
Can We DAMPen the Cross-Talk between the Lung and Kidney in the ICU? Am J Respir Crit Care Med. 2018 Nov 01; 198(9):1220-1222. Hepokoski ML, Bellinghausen AL, Bojanowski CM, Malhotra A. PMID: 30153048; PMCID: PMC6221576.

View in: PubMed Mentions: 1 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
Ventilator-Induced Kidney Injury: Are Novel Biomarkers the Key to Prevention? Nephron. 2018; 140(2):90-93. Hepokoski ML, Malhotra A, Singh P, Crotty Alexander LE. PMID: 29996132; PMCID: PMC6165693.

View in: PubMed Mentions: 6 Fields:
Nep Nephrology
Translation:Humans
Prone positioning in acute respiratory distress syndrome: why aren't we using it more? J Thorac Dis. 2018 Apr; 10(Suppl 9):S1020-S1024. Hepokoski ML, Odish M, Malhotra A. PMID: 29849212; PMCID: PMC5949405.

View in: PubMed Mentions: 5
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice. Am J Physiol Regul Integr Comp Physiol. 2018 06 01; 314(6):R834-R847. Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC. PMID: 29384700; PMCID: PMC6032308.

View in: PubMed Mentions: 56 Fields:
Phy Physiology
Translation:Humans Animals
Renal Oxygenation and Hemodynamics in Kidney Injury. Nephron. 2017; 137(4):260-263. Bullen A, Liu ZZ, Hepokoski M, Li Y, Singh P. PMID: 28614837; PMCID: PMC5732093.

View in: PubMed Mentions: 8 Fields:
Nep Nephrology
Translation:Humans
Update in Critical Care Medicine: Evidence Published in 2016. Ann Intern Med. 2017 04 04; 166(7):W20-W26. Hepokoski M, Malhotra A. PMID: 28358929; PMCID: PMC5483325.

View in: PubMed Mentions: Fields:
Int Internal Medicine
Prediction of human core temperature rise and moisture loss in refuge alternatives for underground coal mines. Trans Soc Min Metall Explor Inc. 2017 Jan; 342:29-35. Klein M, Yantek DS, Hepokoski M, Yan L. PMID: 29545729; PMCID: PMC5849269.

View in: PubMed Mentions: 1
Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney. Am J Physiol Renal Physiol. 2017 04 01; 312(4):F654-F660. Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P. PMID: 28365585; PMCID: PMC5407070.

View in: PubMed Mentions: 15 Fields:
Nep Nephrology Phy Physiology
Translation:Animals Cells
Spontaneous Pneumothorax Complicating Chronic Hepatic Hydrothorax: Successful Treatment by Small Bore Chest Tube. J Bronchology Interv Pulmonol. 2016 Oct; 23(4):e43-e45. Hepokoski M, Makani SS, Lerner AD, Crotty Alexander LE. PMID: 27764014.

View in: PubMed Mentions: Fields:
Pul Pulmonary Medicine
Translation:Humans
Mechanical ventilation in acute respiratory distress syndrome at ATS 2016: the search for a patient-specific strategy. J Thorac Dis. 2016 Jul; 8(Suppl 7):S550-2. Hepokoski M, Owens RL, Malhotra A, Beitler JR. PMID: 27606091; PMCID: PMC4990680.

View in: PubMed Mentions: 3
Mechanisms and implications of the link between sleep apnoea and chronic kidney disease. Respirology. 2016 May; 21(4):578-9. Hepokoski ML, Wali AR, Sarmiento KF. PMID: 27030604.

View in: PubMed Mentions: Fields:
Pul Pulmonary Medicine
Translation:Humans