Aaron Carlin

Title(s)Assistant Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego, San DiegoFellowship & Chief Fellowship06/2015Infectious Diseases
    University of California, San Diego, San DiegoResidency06/2011Internal Medicine
    University of California, San Diego, San DiegoMD, PhD06/2009Medicine, Biomedical Sciences
    University of California, Los Angeles, Los AngelesBS/BA06/2000Microbiology & Molecular Genetics, Philosophy
    Collapse Awards and Honors
    University of California, San Diego2008Gold Humanism Honor Society
    Kiwanis Club of San Diego Foundation2008  - 2009Walter A. Zitlau Memorial Award
    University of California, San Diego2008  - 2009Department of Pediatrics Award
    University of California, San Diego2010  - 2011Excellence in Teaching Award
    UCSD2017  - 2018KL2 Career Development Award
    2017  - 2022Burroughs Wellcome Career Award for Medical Scientists
    UCSD2020National Center of Leadership in Academic Medicine

    Collapse Overview 
    Collapse Overview
    Dr. Aaron Carlin received his received his M.D. and Ph.D. at UCSD. After graduation, Dr. Carlin joined the Physician Scientist Training Program at UCSD where he completed a Residency in Internal Medicine and a Fellowship and Chief Fellowship in Infectious Diseases. He subsequently joined the UCSD Department of Medicine, Division of Infectious Diseases. In addition to attending on the Solid Organ Transplant and Hematology/Oncology Infectious Disease services, Dr. Carlin conducts basic and translational research that utilizes cutting edge molecular techniques to understand the mechanisms by which emerging and reemerging pathogens, like Zika virus, Dengue virus, SARS-CoV-2 and Coccidioides, cause disease in humans. His approach focuses on identifying mechanisms by which anti-viral transcriptional programs are regulated in myeloid cells and how pathogenic viruses subvert host responses to cause human disease. Ultimately, Dr. Carlin aims to exploit this detailed understanding of host-viral interactions to understand how and why certain microorganisms cause human disease, develop new methods for diagnosing infectious disease and identify the best targets for new antimicrobials.

    Collapse Research 
    Collapse Research Activities and Funding
    Revising Anti-coronavirus Compounds to Enhance Activity and Optimize Delivery
    NIH R01AI161348Sep 1, 2021 - Aug 31, 2024
    Role: Co-Investigator
    RADx-Rad Discoveries & Data: Consortium Coordination Center Program Organization
    NIH U24LM013755Dec 21, 2020 - Nov 30, 2024
    Role: Co-Investigator
    Investigating Fundamental Gaps in Valley Fever Knowledge
    UCOP U.C. Valley Fever ResearchSep 1, 2019 - Aug 31, 2022
    Role: Co-Investigator
    Deconvolution of pro- and anti-viral responses to Dengue virus and Zika Virus infections
    NIH K08AI130381Jan 1, 2019 - Dec 31, 2023
    Role: Principal Investigator
    Deciphering Human Innate Immune Responses to Zika Virus Infection
    Burroughs Wellcome Career Award for Medical ScientistsJan 1, 2018 - Jan 1, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity. Sci Adv. 2021 08; 7(34). Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. PMID: 34407940.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Dataset on optimization and development of a point-of-care glucometer-based SARS-CoV-2 detection assay using aptamers. Data Brief. 2021 Oct; 38:107278. Singh NK, Ray P, Carlin AF, Morgan SC, Magallanes C, Laurent LC, Aronoff-Spencer ES, Hall DA. PMID: 34401413.
      View in: PubMed   Mentions:
    3. Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0115521. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 34310217.
      View in: PubMed   Mentions: 1     Fields:    
    4. Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence. bioRxiv. 2021 Jul 19. Salido RA, Cantú VJ, Clark AE, Leibel SL, Foroughishafiei A, Saha A, Hakim A, Nouri A, Lastrella AL, Castro-Martínez A, Plascencia A, Kapadia B, Xia B, Ruiz C, Marotz CA, Maunder D, Lawrence ES, Smoot EW, Eisner E, Crescini ES, Kohn L, Franco Vargas L, Chacón M, Betty M, Machnicki M, Wu MY, Baer NA, Belda-Ferre P, De Hoff P, Seaver P, Ostrander RT, Tsai R, Sathe S, Aigner S, Morgan SC, Ngo TT, Barber T, Cheung W, Carlin AF, Yeo GW, Laurent LC, Fielding-Miller R, Knight R. PMID: 34312621.
      View in: PubMed   Mentions:
    5. A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology. Nat Med. 2021 09; 27(9):1600-1606. Wang L, Sievert D, Clark AE, Lee S, Federman H, Gastfriend BD, Shusta EV, Palecek SP, Carlin AF, Gleeson JG. PMID: 34244682.
      View in: PubMed   Mentions: 3     Fields:    
    6. Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs. bioRxiv. 2021 Jun 07. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 32869033.
      View in: PubMed   Mentions:
    7. Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. PLoS Pathog. 2021 05; 17(5):e1009519. Park SH, Siddiqi H, Castro DV, De Angelis AA, Oom AL, Stoneham CA, Lewinski MK, Clark AE, Croker BA, Carlin AF, Guatelli J, Opella SJ. PMID: 34003853.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Transcriptional Analysis of Coccidioides immitis Mycelia and Spherules by RNA Sequencing. J Fungi (Basel). 2021 May 07; 7(5). Carlin AF, Beyhan S, Peña JF, Stajich JE, Viriyakosol S, Fierer J, Kirkland TN. PMID: 34067070.
      View in: PubMed   Mentions:
    9. METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection. Cell Rep. 2021 05 11; 35(6):109091. Li N, Hui H, Bray B, Gonzalez GM, Zeller M, Anderson KG, Knight R, Smith D, Wang Y, Carlin AF, Rana TM. PMID: 33961823.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS Chem Biol. 2021 04 16; 16(4):642-650. Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Kocurek KI, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Yoon MC, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Hook V, Frueh F, Hurst BL, Wang H, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. PMID: 33787221.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26. Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697.
      View in: PubMed   Mentions:
    12. Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib. Clin Case Rep. 2021 Apr; 9(4):2228-2235. Frankel AE, Reddy R, DeSuza KR, Deeb K, Carlin AF, Smith D, Xie Y, Naik E, Silver RT, Hasselbalch HC. PMID: 33936671.
      View in: PubMed   Mentions:
    13. Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer. Biosens Bioelectron. 2021 May 15; 180:113111. Singh NK, Ray P, Carlin AF, Magallanes C, Morgan SC, Laurent LC, Aronoff-Spencer ES, Hall DA. PMID: 33743492.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    14. Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids. Stem Cell Reports. 2021 03 09; 16(3):437-445. Tiwari SK, Wang S, Smith D, Carlin AF, Rana TM. PMID: 33631122.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors. PLoS Pathog. 2021 02; 17(2):e1009165. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Lee JC, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Ben-Shalom N, Navon M, Rafael D, Sharim H, Kiner E, Griffis ER, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dessau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33571304.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. A Human 3D neural assembloid model for SARS-CoV-2 infection. bioRxiv. 2021 Feb 09. Wang L, Sievert D, Clark AE, Federman H, Gastfriend BD, Shusta E, Palecek SP, Carlin AF, Gleeson J. PMID: 33594369.
      View in: PubMed   Mentions:
    17. Interleukin-8 Receptor 2 (IL-8R2)-Deficient Mice Are More Resistant to Pulmonary Coccidioidomycosis than Control Mice. Infect Immun. 2020 12 15; 89(1). Carlin AF, Viriyakosol S, Okamoto S, Walls L, Fierer J. PMID: 33106296.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells. bioRxiv. 2020 Oct 30. Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Frueh F, Hurst BL, Wang H, Kocurek KI, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. PMID: 33140046.
      View in: PubMed   Mentions:
    19. Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors. bioRxiv. 2020 Oct 06. Mor M, Werbner M, Alter J, Safra M, Chomsky E, Hada-Neeman S, Polonsky K, Nowell CJ, Clark AE, Roitburd-Berman A, Shalom NB, Navon M, Rafael D, Sharim H, Kiner E, Griffis E, Gershoni JM, Kobiler O, Leibel SL, Zimhony O, Carlin AF, Yaari G, Dassau M, Gal-Tanamy M, Hagin D, Croker BA, Freund NT. PMID: 33052341.
      View in: PubMed   Mentions:
    20. Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. EMBO J. 2020 11 02; 39(21):e106057. Wang S, Li W, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM. PMID: 32944968.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020 11 12; 183(4):1043-1057.e15. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32970989.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansCellsPHPublic Health
    22. Rationale for American Society of Retina Specialists Best Practice Recommendations for Conducting Vitreoretinal Surgery during the COVID-19 Era. J Vitreoretin Dis. 2020 Oct 01; 4(5):420-429. Chao DL, Sridhar J, Kuriyan AE, Leng T, Barnett BP, Carlin AF, Wykoff CC, Gayer S, Mruthyunjaya P, Yonekawa Y, Fawzi AA, Berrocal AM, Yeh S, Ting D, Modi Y, Zacks DN, Yannuzzi N, Afshari NA, Murray T. PMID: 34222758.
      View in: PubMed   Mentions:
    23. SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. bioRxiv. 2020 Jul 14. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Painter CD, Thacker BE, Glass CA, Narayanan A, Majowicz SA, Zhang Y, Torres JL, Golden GJ, Porell R, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser B, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Leibel SL, Chanda SK, Schmidt AG, Godula K, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32699853.
      View in: PubMed   Mentions:
    24. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell. 2020 06 25; 181(7):1489-1501.e15. Grifoni A, Weiskopf D, Ramirez SI, Mateus J, Dan JM, Moderbacher CR, Rawlings SA, Sutherland A, Premkumar L, Jadi RS, Marrama D, de Silva AM, Frazier A, Carlin AF, Greenbaum JA, Peters B, Krammer F, Smith DM, Crotty S, Sette A. PMID: 32473127.
      View in: PubMed   Mentions: 883     Fields:    Translation:HumansCellsPHPublic Health
    25. A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PLoS Negl Trop Dis. 2018 12; 12(12):e0007053. Carlin AF, Wen J, Vizcarra EA, McCauley M, Chaillon A, Akrami K, Kim C, Ngono AE, Lara-Marquez ML, Smith DM, Glass CK, Schooley RT, Benner C, Shresta S. PMID: 30596671.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Genome-wide approaches to unravelling host-virus interactions in Dengue and Zika infections. Curr Opin Virol. 2019 02; 34:29-38. Carlin AF, Shresta S. PMID: 30576956.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    27. Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice. . 2018 11 14; 24(5):743-750.e5. Fowler AM, Tang WW, Young MP, Mamidi A, Viramontes KM, McCauley MD, Carlin AF, Schooley RT, Swanstrom J, Baric RS, Govero J, Diamond MS, Shresta S. PMID: 30439343.
      View in: PubMed   Mentions:
    28. Case Report: A Common Source Outbreak of Anisakidosis in the United States and Postexposure Prophylaxis of Family Collaterals. Am J Trop Med Hyg. 2018 11; 99(5):1219-1221. Carlin AF, Abeles S, Chin NA, Lin GY, Young M, Vinetz JM. PMID: 30226150.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    29. Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9172-E9181. Carlin AF, Vizcarra EA, Branche E, Viramontes KM, Suarez-Amaran L, Ley K, Heinz S, Benner C, Shresta S, Glass CK. PMID: 30206152.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    30. An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses. Cell Rep. 2017 Nov 07; 21(6):1600-1612. Carlin AF, Plummer EM, Vizcarra EA, Sheets N, Joo Y, Tang W, Day J, Greenbaum J, Glass CK, Diamond MS, Shresta S. PMID: 29117564.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    31. Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain. J Biol Chem. 2017 02 17; 292(7):2557-2570. Naito-Matsui Y, Davies LR, Takematsu H, Chou HH, Tangvoranuntakul P, Carlin AF, Verhagen A, Heyser CJ, Yoo SW, Choudhury B, Paton JC, Paton AW, Varki NM, Schnaar RL, Varki A. PMID: 28049733.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    32. SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab. 2017 02 07; 25(2):412-427. Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. PMID: 28041958.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    33. Temporal dynamics of inflammatory cytokines/chemokines during sofosbuvir and ribavirin therapy for genotype 2 and 3 hepatitis C infection. Hepatology. 2015 Oct; 62(4):1047-58. Carlin AF, Aristizabal P, Song Q, Wang H, Paulson MS, Stamm LM, Schooley RT, Wyles DL. PMID: 26147061.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    34. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. J Exp Med. 2014 Jun 02; 211(6):1231-42. Ali SR, Fong JJ, Carlin AF, Busch TD, Linden R, Angata T, Areschoug T, Parast M, Varki N, Murray J, Nizet V, Varki A. PMID: 24799499.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    35. Hyaluronan digestion controls DC migration from the skin. J Clin Invest. 2014 Mar; 124(3):1309-19. Muto J, Morioka Y, Yamasaki K, Kim M, Garcia A, Carlin AF, Varki A, Gallo RL. PMID: 24487587.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    36. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23. Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. PMID: 24189069.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    37. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med. 2009 Aug 31; 206(9):1845-52. Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. PMID: 19687228.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    38. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 2009 Nov; 19(11):1204-13. Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. PMID: 19643844.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    39. Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5. J Exp Med. 2009 Aug 03; 206(8):1691-9. Carlin AF, Chang YC, Areschoug T, Lindahl G, Hurtado-Ziola N, King CC, Varki A, Nizet V. PMID: 19596804.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    40. Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response. Blood. 2009 Apr 02; 113(14):3333-6. Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A. PMID: 19196661.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansCells
    41. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. J Biol Chem. 2007 Sep 21; 282(38):27562-71. Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. PMID: 17646166.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    42. Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. J Bacteriol. 2007 Feb; 189(4):1231-7. Carlin AF, Lewis AL, Varki A, Nizet V. PMID: 16997964.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
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