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Karen Mccowen

Title(s)Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Glucagon-like peptide-1 receptor agonists for the treatment of obstructive sleep apnea. Curr Opin Pulm Med. 2025 Nov 01; 31(6):591-596. D'Annibale DA, Mimoto M, McCowen KC, Malhotra A. PMID: 40855981; PMCID: PMC12538296.
      View in: PubMed   Mentions:    Fields:    
    2. The Potential Role of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists and Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Agonists in Obstructive Sleep Apnea and Obesity. Curr Pulmonol Rep. 2025; 14(1):19. Ellberg CC, Schwartz H, Witt A, McCowen KC, Fuentes AL, Malhotra A. PMID: 40727552; PMCID: PMC12289732.
      View in: PubMed   Mentions:
    3. Hyperthyroidism Due to Graves Disease After Radiofrequency Ablation. JCEM Case Rep. 2023 May; 1(3):luad056. McAninch EA, Desai K, McCowen KC, Orloff LA. PMID: 37908568; PMCID: PMC10580446.
      View in: PubMed   Mentions: 4  
    4. Sleep Apnea, Obesity, and Diabetes - an Intertwined Trio. Curr Diab Rep. 2023 07; 23(7):165-171. Kurnool S, McCowen KC, Bernstein NA, Malhotra A. PMID: 37148488; PMCID: PMC10239381.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    5. Voice Outcomes From Direct Vocal Fold Testosterone Injections, a Case Report. Laryngoscope. 2023 05; 133(5):1211-1213. Vahabzadeh-Hagh AM, Walsh E, Hamidi V, McCowen K. PMID: 36594494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. ALPELISIB - INDUCED HYPERGLYCEMIA. Acta Endocrinol (Buchar). 2022 Jan-Mar; 18(1):115-117. Ekanayake PS, Gerwer J, Mccowen K. PMID: 35975254; PMCID: PMC9365413.
      View in: PubMed   Mentions: 1  
    7. SURPRISINGLY FEW WOMEN WITH SEVERE OSTEOPOROSIS BY BONE DENSITOMETRY UNDERGO WORKUP FOR SECONDARY CAUSES - A RETROSPECTIVE EVALUATION. Acta Endocrinol (Buchar). 2021 Oct-Dec; 17(4):537-542. Nguyen K, Chen X, Hughes T, Hofflich H, Woods GN, McCowen KC. PMID: 35747871; PMCID: PMC9206146.
      View in: PubMed   Mentions: 5  
    8. Inpatient use of metformin and acarbose is associated with reduced mortality of COVID-19 patients with type 2 diabetes mellitus. Endocrinol Diabetes Metab. 2022 01; 5(1):e00301. Li J, Wei Q, McCowen KC, Xiong W, Liu J, Jiang W, Thomas RL, Hepokoski M, He M, Shyy JYJ, Malhotra A, Xiong N, Li WX. PMID: 34585841; PMCID: PMC8646242.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    9. Inappropriate requesting of parathyroid scintigraphy at an academic medical center. Head Neck. 2021 11; 43(11):3404-3407. Kimura B, Nagelberg J, Koo SJ, Bykowski J, Brumund KT, McCowen KC. PMID: 34378837.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Fasting hypoglycaemia secondary to carnitine deficiency: a late consequence of gastric bypass. BMJ Case Rep. 2021 Jul 19; 14(7). Chen X, Kimura B, Nagelberg J, McCowen KC. PMID: 34281938; PMCID: PMC8291321.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Weakness and Low Potassium in a 47-Year-Old Male. Clin Chem. 2021 07 06; 67(7):941-944. Kolar MJ, Chae H, McCowen KC, Fitzgerald RL, Bevins N. PMID: 34229342.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Inpatient Use of Metformin and Acarbose Is Associated with Reduced Mortality of COVID-19 Patients with Type 2 Diabetes Mellitus. Res Sq. 2021 Mar 26. Li W, Li J, Wei Q, McCowen K, Xiong W, Liu J, Jiang W, Thomas R, Hepokoski M, He M, Shyy J, Malhotra A, Xiong N. PMID: 33791691; PMCID: PMC8010742.
      View in: PubMed   Mentions:
    13. Metformin Use in Diabetes Prior to Hospitalization: Effects on Mortality in Covid-19. Endocr Pract. 2020 Oct; 26(10):1166-1172. Li J, Wei Q, Li WX, McCowen KC, Xiong W, Liu J, Jiang W, Marin T, Thomas RL, He M, Gongol B, Hepokoski M, Yuan JX, Shyy JY, Xiong N, Malhotra A. PMID: 33471718; PMCID: PMC7834011.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    14. ACE2, Metformin, and COVID-19. iScience. 2020 Jul 31; 23(9):101425. Malhotra A, Hepokoski M, McCowen KC, Y-J Shyy J. PMID: 32818905; PMCID: PMC7452173.
      View in: PubMed   Mentions: 38  
    15. Rapid onset type 1 diabetes with anti-PD-1 directed therapy. Oncotarget. 2020 Jul 14; 11(28):2740-2746. Yun K, Daniels G, Gold K, Mccowen K, Patel SP. PMID: 32733645; PMCID: PMC7367652.
      View in: PubMed   Mentions: 10     Fields:    
    16. Rebound Vertebral Fractures in a Patient With Lung Cancer After Oncology-Dose Denosumab Discontinuation: A Cautionary Tale. Mayo Clin Proc Innov Qual Outcomes. 2019 Jun; 3(2):235-237. Tyan A, Patel SP, Block S, Hughes T, McCowen KC. PMID: 31193884; PMCID: PMC6543257.
      View in: PubMed   Mentions: 10  
    17. Sleep apnea, metabolic disease, and the cutting edge of therapy. Metabolism. 2018 07; 84:94-98. Light M, McCowen K, Malhotra A, Mesarwi OA. PMID: 28966076; PMCID: PMC5874161.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    18. Pioglitazone for diabetes prevention. N Engl J Med. 2011 07 14; 365(2):182-3; author reply 183-4. McCowen KC, Fajtova VT. PMID: 21751926.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Clinical practice. Glycemic control in the ICU. N Engl J Med. 2010 Dec 23; 363(26):2540-6. Kavanagh BP, McCowen KC. PMID: 21175316.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    20. A simple method of supplementation of omega-3 polyunsaturated fatty acids: use of fortified yogurt in healthy volunteers. Nutr Clin Pract. 2010 Dec; 25(6):641-5. McCowen KC, Ling PR, Decker E, Djordjevic D, Roberts RF, Coupland JN, Bistrian BR. PMID: 21139129; PMCID: PMC3216397.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    21. Effect of a fish oil-containing beverage on changes in plasma lipid fatty acids in patients with malabsorption. Nutr Clin Pract. 2010 Oct; 25(5):517-23. McCowen KC, Ling PR, Ollero M, Tawa N, Bistrian BR. PMID: 20962312; PMCID: PMC4542052.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Effect of SSRI antidepressants on L-thyroxine requirements. Thyroid. 2010 Aug; 20(8):937; author reply 937-8. McCowen KC, Garber JR. PMID: 20678001.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Drug-induced endocrine disorders in the intensive care unit. Crit Care Med. 2010 Jun; 38(6 Suppl):S219-30. Thomas Z, Bandali F, McCowen K, Malhotra A. PMID: 20502175.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    24. Nutritional and metabolic support in the adult intensive care unit: key controversies. Crit Care Med. 2006 May; 34(5):1525-31. Bistrian BR, McCowen KC. PMID: 16557154.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Liver and skeletal muscle lipids have differing fatty acid profiles in short-gut rats fed via parenteral nutrition. JPEN J Parenter Enteral Nutr. 2006 Jan-Feb; 30(1):27-31. McCowen KC, Ling PR, Ollero M, Maykel JA, Blanco PG, Bistrian BR. PMID: 16387896.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    26. Essential fatty acids and their derivatives. Curr Opin Gastroenterol. 2005 Mar; 21(2):207-15. McCowen KC, Bistrian BR. PMID: 15711215.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    27. "Evidence-based" medicine derived from systematic reviews or meta-analyses to develop clinical practice guidelines. Nutr Clin Pract. 2004 Dec; 19(6):650-1. Bistrian BR, McCowen KC. PMID: 16215164.
      View in: PubMed   Mentions:    Fields:    
    28. Hyperglycemia and nutrition support: theory and practice. Nutr Clin Pract. 2004 Jun; 19(3):235-44. McCowen KC, Bistrian BR. PMID: 16215111.
      View in: PubMed   Mentions: 7     Fields:    
    29. Abnormal regulation of serum lipid fatty acid profiles in short gut rats fed parenteral nutrition with lipid. Metabolism. 2004 Mar; 53(3):273-7. McCowen KC, Ling PR, Ollero M, Maykel JA, Blanco PG, Bistrian BR. PMID: 15015135.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    30. Immunonutrition: problematic or problem solving? Am J Clin Nutr. 2003 Apr; 77(4):764-70. McCowen KC, Bistrian BR. PMID: 12663270.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    31. Interactions between hypoglycemia and sleep architecture in children with type 1 diabetes mellitus. J Pediatr. 2003 Feb; 142(2):163-8. Pillar G, Schuscheim G, Weiss R, Malhotra A, McCowen KC, Shlitner A, Peled N, Shehadeh N. PMID: 12584538.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    32. Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents. J Endocrinol. 2002 Nov; 175(2):R7-11. McCowen KC, Maykel JA, Bistrian BR, Ling PR. PMID: 12429053.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    33. Immunonutrition in critical illness. Nutr Clin Pract. 2002 Oct; 17(5):265-6. McCowen KC, Bistrian BR. PMID: 16214998.
      View in: PubMed   Mentions: 2     Fields:    
    34. Disturbances in essential fatty acid metabolism in patients receiving long-term home parenteral nutrition. Dig Dis Sci. 2002 Aug; 47(8):1679-85. Ling PR, Ollero M, Khaodhiar L, McCowen K, Keane-Ellison M, Thibault A, Tawa N, Bistrian BR. PMID: 12184517.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    35. Intensive insulin therapy in critically ill patients. N Engl J Med. 2002 May 16; 346(20):1586-8; author reply 1586-8. McCowen KC, Maykel JA, Bistrian BR. PMID: 12017161.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Patterns of plasma leptin and insulin concentrations in hospitalized patients after the initiation of total parenteral nutrition. Am J Clin Nutr. 2002 May; 75(5):931-5. McCowen KC, Ling PR, Friel C, Sternberg J, Forse RA, Burke PA, Bistrian BR. PMID: 11976169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Obesity in mice and men. Obes Res. 2001 Sep; 9(9):592. Bistrian BR, McCowen KC. PMID: 11557841.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    38. Sustained endotoxemia leads to marked down-regulation of early steps in the insulin-signaling cascade. Crit Care Med. 2001 Apr; 29(4):839-46. McCowen KC, Ling PR, Ciccarone A, Mao Y, Chow JC, Bistrian BR, Smith RJ. PMID: 11373480.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    39. Stress-induced hyperglycemia. Crit Care Clin. 2001 Jan; 17(1):107-24. McCowen KC, Malhotra A, Bistrian BR. PMID: 11219223.
      View in: PubMed   Mentions: 319     Fields:    Translation:Humans
    40. Liver disease and home parenteral nutrition. Ann Intern Med. 2000 Dec 19; 133(12):1009-10. McCowen KC, Burke PA, Bistrian BR. PMID: 11119408.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Hypocaloric total parenteral nutrition: effectiveness in prevention of hyperglycemia and infectious complications--a randomized clinical trial. Crit Care Med. 2000 Nov; 28(11):3606-11. McCowen KC, Friel C, Sternberg J, Chan S, Forse RA, Burke PA, Bistrian BR. PMID: 11098961.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCTClinical Trials
    42. Arachidonic acid concentrations in patients with Crohn disease. Am J Clin Nutr. 2000 Apr; 71(4):1008. McCowen KC, Ling PR, Bistrian BR. PMID: 10731511.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo. Endocrinology. 1999 Dec; 140(12):5505-15. Mao Y, Ling PR, Fitzgibbons TP, McCowen KC, Frick GP, Bistrian BR, Smith RJ. PMID: 10579313.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    44. Gangliocytoma masquerading as a prolactinoma. Case report. J Neurosurg. 1999 Sep; 91(3):490-5. McCowen KC, Glickman JN, Black PM, Zervas NT, Lidov HG, Garber JR. PMID: 10470826.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    45. Incidence, prognosis, and etiology of end-stage liver disease in patients receiving home total parenteral nutrition. Surgery. 1999 Jul; 126(1):28-34. Chan S, McCowen KC, Bistrian BR, Thibault A, Keane-Ellison M, Forse RA, Babineau T, Burke P. PMID: 10418589.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    46. Nutrition management in the ICU. Chest. 1999 May; 115(5 Suppl):145S-148S. Chan S, McCowen KC, Blackburn GL. PMID: 10331348.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    47. In vivo insulin signaling in the myocardium of streptozotocin-diabetic rats: opposite effects of diabetes on insulin stimulation of glycogen synthase and c-Fos. Endocrinology. 1999 Mar; 140(3):1141-50. Wang PH, Almahfouz A, Giorgino F, McCowen KC, Smith RJ. PMID: 10067837.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    48. Obesity and its comorbid conditions. Clin Cornerstone. 1999; 2(3):17-31. Khaodhiar L, McCowen KC, Blackburn GL. PMID: 10696282.
      View in: PubMed   Mentions: 138     Fields:    Translation:Humans
    49. Perioperative hyperglycemia, infection or risk? Curr Opin Clin Nutr Metab Care. 1999 Jan; 2(1):79-82. Khaodhiar L, McCowen K, Bistrian B. PMID: 10453334.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    50. Protein-energy malnutrition in dialysis patients. Am J Kidney Dis. 1999 Jan; 33(1):172-5. Bistrian BR, McCowen KC, Chan S. PMID: 9915286.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Leptin signaling in the hypothalamus of normal rats in vivo. Endocrinology. 1998 Nov; 139(11):4442-7. McCowen KC, Chow JC, Smith RJ. PMID: 9794450.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    52. Acid-base disorders. N Engl J Med. 1998 May 28; 338(22):1628-9. Bistrian BR, McCowen KC, Driscoll D. PMID: 9606126.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. Medium-chain triglyceride and n-3 polyunsaturated fatty acid-containing emulsions in intravenous nutrition. Curr Opin Clin Nutr Metab Care. 1998 Mar; 1(2):163-9. Chan S, McCowen KC, Bistrian B. PMID: 10565343.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    54. Elevated serum thyrotropin in thyroxine-treated patients with hypothyroidism given sertraline. N Engl J Med. 1997 Oct 02; 337(14):1010-1. McCowen KC, Garber JR, Spark R. PMID: 9312673.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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