Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Gabriel Haddad

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentNeurosciences
    Address9500 Gilman Drive #0735
    CA La Jolla 92093
    Phone858-822-4740
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Mechanisms Regulating Tolerance to Oxidative Stress in the Brain
      NIH/NINDS R21NS101652Mar 1, 2017 - Feb 28, 2019
      Role: Principal Investigator
      Study of iPS cells-derived neural and glial cells from subjects with Monge's disease
      NIH/NINDS R21NS097899Feb 1, 2017 - Jan 31, 2019
      Role: Principal Investigator
      Endothelin receptors modulate cardiorespiratory function during hypoxia
      NIH/NHLBI R01HL127403Jun 1, 2016 - Feb 29, 2020
      Role: Principal Investigator
      Molecular mechanisms of hypoxia tolerance and susceptibility
      NIH/NHLBI P01HL098053Jul 1, 2010 - Jun 30, 2015
      Role: Principal Investigator
      Resistance to oxidant injury
      NIH/NHLBI R21HL093611Apr 1, 2009 - Mar 31, 2011
      Role: Principal Investigator
      Hypoxia and Consequences: From Molecule to Malady
      NIH/NHLBI R13HL093851Jun 15, 2008 - Jun 14, 2009
      Role: Principal Investigator
      Sleep Mechanisms in Children: Role of Metabolism
      NIH/NHLBI R01HL070919Sep 23, 2002 - Jan 31, 2004
      Role: Principal Investigator
      Roles and mechanisms of Slo and Slack Channels in Brain
      NIH P01NS042202Sep 4, 2001 - Aug 31, 2006
      Role: Co-Investigator
      CYCLICAL HYPOXIA--SUSCEPTIBILITY TO NEURONAL INJURY
      NIH/NHLBI R01HL066327Sep 30, 2000 - Aug 31, 2005
      Role: Principal Investigator
      Molecular basis of cell tolerance to 02 deprivation
      NIH/NINDS R01NS037756Jan 1, 2000 - Apr 3, 2011
      Role: Principal Investigator
      IONIC &METABOLIC MECHANISMS IN HYPOXIC NEURONAL INJURY
      NIH/NINDS R01NS035918Jan 1, 1997 - Dec 31, 2000
      Role: Principal Investigator
      Hypoxia in Development;Injury and Adaptation Mechanisms
      NIH/NICHD P01HD032573Feb 10, 1995 - Jul 31, 2011
      Role: Principal Investigator
      Training in Translational Lung Biology and Pathobiology
      NIH/NHLBI T32HL007778Jul 15, 1994 - Jun 30, 2020
      Role: Principal Investigator
      PRENATAL HYPOXIA--CELLULAR BRAINSTEM MATURATION
      NIH/NICHD R01HD028940Sep 30, 1991 - Aug 31, 1994
      Role: Principal Investigator
      IVEM and Image Analysis Resource
      NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
      Role: Co-Investigator
      POSTNATAL MATURATION &MODULATION OF RESPIRATORY NEURONS
      NIH/NHLBI R01HL039924Sep 30, 1987 - Jun 30, 1998
      Role: Principal Investigator
      BRAIN INJURY DUE TO NEONATAL SEIZURE
      NIH/NINDS R01NS024605Jul 1, 1986 - Jun 30, 1993
      Role: Principal Investigator
      RESPIRATORY MUSCLE TRAINING, METABOLIC &STRUCTURAL BASE
      NIH/NHLBI R01HL034467Jul 1, 1986 - Jun 30, 1990
      Role: Principal Investigator
      ENDORPHINS, SLEEP AND MATURATION OF HYPOXIC RESPONSE
      NIH/NICHD R01HD015736Jul 1, 1981 - Aug 31, 1995
      Role: Principal Investigator
      MUSCULAR FATIGUE
      NIH/NINDS R01NS014756Jul 1, 1978 - Dec 31, 1996
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Azad P, Stobdan T, Zhou D, Hartley I, Akbari A, Bafna V, Haddad G. High-altitude adaptation in humans: from genomics to integrative physiology. J Mol Med (Berl). 2017 Sep 26. PMID: 28951950.
        View in: PubMed
      2. Stobdan T, Akbari A, Azad P, Zhou D, Poulsen O, Appenzeller O, Gonzales GF, Telenti A, Wong EHM, Saini S, Kirkness EF, Venter JC, Bafna V, Haddad G. New insights into the genetic basis of Monge's disease and adaptation to high-altitude. Mol Biol Evol. 2017 Sep 19. PMID: 29029226.
        View in: PubMed
      3. Azad P, Zhao HW, Cabrales PJ, Ronen R, Zhou D, Poulsen O, Appenzeller O, Hsiao YH, Bafna V, Haddad G. Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. J Exp Med. 2016 Nov 14; 213(12):2729-2744. PMID: 27821551.
        View in: PubMed
      4. Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad G. The Na+/HCO3- co-transporter is protective during ischemia in astrocytes. Neuroscience. 2016 Dec 17; 339:329-337. PMID: 27717805.
        View in: PubMed
      5. Imamura T, Poulsen O, Haddad G. Intermittent hypoxia induces murine macrophage foam cell formation by IKK-ß-dependent NF-?B pathway activation. J Appl Physiol (1985). 2016 Sep 01; 121(3):670-7. PMID: 27471237.
        View in: PubMed
      6. Aggarwal DD, Rashkovetsky E, Michalak P, Cohen I, Ronin Y, Zhou D, Haddad G, Korol AB. Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits. BMC Biol. 2015 Nov 27; 13:101. PMID: 26614097; PMCID: PMC4661966.
      7. Zarndt R, Piloto S, Powell FL, Haddad G, Bodmer R, Ocorr K. Cardiac responses to hypoxia and reoxygenation in Drosophila. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 01; 309(11):R1347-57. PMID: 26377557; PMCID: PMC4698404 [Available on 12/01/16].
      8. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad G. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. PMID: 26240367; PMCID: PMC4547246.
      9. Manchenkov T, Pasillas MP, Haddad G, Imam FB. Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda). 2015 Apr 03; 5(6):1107-16. PMID: 25840431; PMCID: PMC4478541.
      10. Huang H, Lu-Bo Y, Haddad G. A Drosophila ABC transporter regulates lifespan. PLoS Genet. 2014 Dec; 10(12):e1004844. PMID: 25474322; PMCID: PMC4256198.
      11. Ronen R, Zhou D, Bafna V, Haddad G. The genetic basis of chronic mountain sickness. Physiology (Bethesda). 2014 Nov; 29(6):403-12. PMID: 25362634; PMCID: PMC4280153.
      12. Gersten M, Zhou D, Azad P, Haddad G, Subramaniam S. Wnt pathway activation increases hypoxia tolerance during development. PLoS One. 2014; 9(8):e103292. PMID: 25093834; PMCID: PMC4122365.
      13. Gu XQ, Pamenter ME, Siemen D, Sun X, Haddad G. Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma. Glia. 2014 Apr; 62(4):504-13. PMID: 24446243.
        View in: PubMed
      14. Hartley I, Elkhoury FF, Heon Shin J, Xie B, Gu X, Gao Y, Zhou D, Haddad G. Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures. PLoS One. 2013; 8(10):e77859. PMID: 24205000; PMCID: PMC3808424.
      15. Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad G. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab. 2014 Feb; 3(1):42-54. PMID: 24567903; PMCID: PMC3929909.
      16. Yin S, Xue J, Sun H, Wen B, Wang Q, Perkins G, Zhao HW, Ellisman MH, Hsiao YH, Yin L, Xie Y, Hou G, Zi J, Lin L, Haddad G, Zhou D, Liu S. Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions. PLoS One. 2013; 8(9):e74011. PMID: 24069262; PMCID: PMC3771901.
      17. Douglas RM, Bowden K, Pattison J, Peterson AB, Juliano J, Dalton ND, Gu Y, Alvarez E, Imamura T, Peterson KL, Witztum JL, Haddad G, Li AC. Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985). 2013 Dec; 115(11):1694-704. PMID: 23990245; PMCID: PMC3882740.
      18. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad G. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 05; 93(3):452-62. PMID: 23954164; PMCID: PMC3769925.
      19. Zhou D, Haddad G. Genetic analysis of hypoxia tolerance and susceptibility in Drosophila and humans. Annu Rev Genomics Hum Genet. 2013; 14:25-43. PMID: 23808366.
        View in: PubMed
      20. Xie L, Ng C, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad G, Bourne PE, Xie L. Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia. BMC Genomics. 2013; 14 Suppl 3:S9. PMID: 23819581; PMCID: PMC3665574.
      21. Pamenter ME, Perkins GA, Gu XQ, Ellisman MH, Haddad G. DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress. PLoS One. 2013; 8(4):e60804. PMID: 23577164; PMCID: PMC3618322.
      22. Douglas RM, Chen AH, Iniguez A, Wang J, Fu Z, Powell FL, Haddad G, Yao H. Chemokine receptor-like 2 is involved in ischemic brain injury. J Exp Stroke Transl Med. 2013 Feb 17; 6:1-6. PMID: 23847708.
        View in: PubMed
      23. Pamenter ME, Perkins GA, McGinness AK, Gu XQ, Ellisman MH, Haddad G. Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra. PLoS One. 2012; 7(12):e51469. PMID: 23251543; PMCID: PMC3520810.
      24. Azad P, Haddad G. Genetic animal models of preconditioning. Transl Stroke Res. 2013 Feb; 4(1):51-5. PMID: 23565128; PMCID: PMC3614364.
      25. Azad P, Zhou D, Zarndt R, Haddad G. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. G3 (Bethesda). 2012 Oct; 2(10):1169-78. PMID: 23050227; PMCID: PMC3464109.
      26. Ryu J, Haddad G, Carlo WA. Clinical effectiveness and safety of permissive hypercapnia. Clin Perinatol. 2012 Sep; 39(3):603-12. PMID: 22954272.
        View in: PubMed
      27. Pamenter ME, Ryu J, Hua ST, Perkins GA, Mendiola VL, Gu XQ, Ellisman MH, Haddad G. DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release. PLoS One. 2012; 7(8):e43995. PMID: 22937143; PMCID: PMC3427179.
      28. Heinrichsen ET, Haddad G. Role of high-fat diet in stress response of Drosophila. PLoS One. 2012; 7(8):e42587. PMID: 22870336; PMCID: PMC3411628.
      29. Pamenter ME, Hogg DW, Gu XQ, Buck LT, Haddad G. Painted turtle cortex is resistant to an in vitro mimic of the ischemic mammalian penumbra. J Cereb Blood Flow Metab. 2012 Nov; 32(11):2033-43. PMID: 22805876; PMCID: PMC3493991.
      30. Lesser DJ, Haddad G, Bush RA, Pian MS. The utility of a portable recording device for screening of obstructive sleep apnea in obese adolescents. J Clin Sleep Med. 2012 Jun 15; 8(3):271-7. PMID: 22701384; PMCID: PMC3365085.
      31. Ali SS, Hsiao M, Zhao HW, Dugan LL, Haddad G, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. PLoS One. 2012; 7(5):e36801. PMID: 22574227; PMCID: PMC3344937.
      32. Pamenter ME, Ali SS, Tang Q, Finley JC, Gu XQ, Dugan LL, Haddad G. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Res. 2012 May 03; 1452:165-72. PMID: 22459046; PMCID: PMC3326196.
      33. Zhao HW, Ali SS, Haddad G. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transport chain activity leading to a reduction of superoxide production? Antioxid Redox Signal. 2012 May 15; 16(10):1071-6. PMID: 22229946; PMCID: PMC3315163.
      34. Udpa N, Zhou D, Haddad G, Bafna V. Tests of selection in pooled case-control data: an empirical study. Front Genet. 2011; 2:83. PMID: 22303377; PMCID: PMC3268381.
      35. Haddad G. Does the brain gain back energy during sleep? But what does it mean? Sleep. 2011 Jul 01; 34(7):835-6. PMID: 21731130; PMCID: PMC3119555.
      36. Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad G. Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro. Am J Physiol Regul Integr Comp Physiol. 2011 Sep; 301(3):R727-45. PMID: 21677276; PMCID: PMC3174756.
      37. Azad P, Ryu J, Haddad G. Distinct role of Hsp70 in Drosophila hemocytes during severe hypoxia. Free Radic Biol Med. 2011 Jul 15; 51(2):530-8. PMID: 21616137; PMCID: PMC3138732.
      38. Zhou D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer KA, Posakony JW, Subramaniam S, Bafna V, Haddad G. Experimental selection of hypoxia-tolerant Drosophila melanogaster. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2349-54. PMID: 21262834; PMCID: PMC3038716.
      39. Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad G. Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. J Neurol Res. 2011; 1(5). PMID: 24348887.
        View in: PubMed
      40. Zhao HW, Zhou D, Haddad G. Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. J Biol Chem. 2011 Feb 25; 286(8):6211-8. PMID: 21148307; PMCID: PMC3057857.
      41. Zhao HW, Zhou D, Nizet V, Haddad G. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010 Jul 23; 5(7):e11701. PMID: 20668515; PMCID: PMC2909141.
      42. Felfly H, Muotri A, Yao H, Haddad G. Hematopoietic stem cell transplantation protects mice from lethal stroke. Exp Neurol. 2010 Oct; 225(2):284-93. PMID: 20547154; PMCID: PMC2963425.
      43. Xue J, Mraiche F, Zhou D, Karmazyn M, Oka T, Fliegel L, Haddad G. Elevated myocardial Na+/H+ exchanger isoform 1 activity elicits gene expression that leads to cardiac hypertrophy. Physiol Genomics. 2010 Aug; 42(3):374-83. PMID: 20460605; PMCID: PMC2929882.
      44. Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad G, Poellinger L, Peet DJ, Powell F, Johnson RS. The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metab. 2010 May 05; 11(5):364-78. PMID: 20399150; PMCID: PMC2893150.
      45. Ryu J, Heldt GP, Nguyen M, Gavrialov O, Haddad G. Chronic hypercapnia alters lung matrix composition in mouse pups. J Appl Physiol (1985). 2010 Jul; 109(1):203-10. PMID: 20360436; PMCID: PMC2904197.
      46. Douglas RM, Ryu J, Kanaan A, Del Carmen Rivero M, Dugan LL, Haddad G, Ali SS. Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. Am J Physiol Cell Physiol. 2010 Jun; 298(6):C1594-602. PMID: 20357179; PMCID: PMC2889641.
      47. Sun X, Yao H, Douglas RM, Gu XQ, Wang J, Haddad G. Insulin/PI3K signaling protects dentate neurons from oxygen-glucose deprivation in organotypic slice cultures. J Neurochem. 2010 Jan; 112(2):377-88. PMID: 19860861; PMCID: PMC4524356.
      48. Azad P, Haddad G. Survival in acute and severe low o environment: use of a genetic model system. Ann N Y Acad Sci. 2009 Oct; 1177:39-47. PMID: 19845605.
        View in: PubMed
      49. Feala JD, Coquin L, Zhou D, Haddad G, Paternostro G, McCulloch AD. Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis. BMC Syst Biol. 2009 Sep 09; 3:91. PMID: 19740440; PMCID: PMC2749811.
      50. Zhou D, Visk DW, Haddad G. Drosophila, a golden bug, for the dissection of the genetic basis of tolerance and susceptibility to hypoxia. Pediatr Res. 2009 Sep; 66(3):239-47. PMID: 19542900.
        View in: PubMed
      51. Guma M, Rius J, Duong-Polk KX, Haddad G, Lindsey JD, Karin M. Genetic and pharmacological inhibition of JNK ameliorates hypoxia-induced retinopathy through interference with VEGF expression. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8760-5. PMID: 19433784; PMCID: PMC2688966.
      52. Azad P, Zhou D, Russo E, Haddad G. Distinct mechanisms underlying tolerance to intermittent and constant hypoxia in Drosophila melanogaster. PLoS One. 2009; 4(4):e5371. PMID: 19401761; PMCID: PMC2670512.
      53. Yao H, Felfly H, Wang J, Zhou D, Haddad G. DIDS protects against neuronal injury by blocking Toll-like receptor 2 activated-mechanisms. J Neurochem. 2009 Feb; 108(3):835-46. PMID: 19077053; PMCID: PMC2782475.
      54. Douglas RM, Haddad G. Can O2 dysregulation induce premature aging? Physiology (Bethesda). 2008 Dec; 23:333-49. PMID: 19074741.
        View in: PubMed
      55. Zhou D, Xue J, Lai JC, Schork NJ, White KP, Haddad G. Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet. 2008 Oct; 4(10):e1000221. PMID: 18927626; PMCID: PMC2556400.
      56. Iacobas DA, Fan C, Iacobas S, Haddad G. Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival. Funct Integr Genomics. 2008 Aug; 8(3):265-75. PMID: 18446526; PMCID: PMC2856931.
      57. Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad G, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 2008 Jun 05; 453(7196):807-11. PMID: 18432192; PMCID: PMC2669289.
      58. Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 2008 Apr 18; 133(2):223-34. PMID: 18423195; PMCID: PMC2849644.
      59. Zhou D, Wang J, Zapala MA, Xue J, Schork NJ, Haddad G. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiol Genomics. 2008 Feb 19; 32(3):370-9. PMID: 18056785.
        View in: PubMed
      60. Sun X, Yao H, Zhou D, Gu X, Haddad G. Modulation of hSlo BK current inactivation by fatty acid esters of CoA. J Neurochem. 2008 Mar; 104(5):1394-403. PMID: 18005338.
        View in: PubMed
      61. Xue J, Zhou D, Yao H, Haddad G. Role of transporters and ion channels in neuronal injury under hypoxia. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R451-7. PMID: 17977915.
        View in: PubMed
      62. Yao H, Sun X, Gu X, Wang J, Haddad G. Cell death in an ischemic infarct rim model. J Neurochem. 2007 Nov; 103(4):1644-53. PMID: 17727626.
        View in: PubMed
      63. Kanaan A, Douglas RM, Alper SL, Boron WF, Haddad G. Effect of chronic elevated carbon dioxide on the expression of acid-base transporters in the neonatal and adult mouse. Am J Physiol Regul Integr Comp Physiol. 2007 Sep; 293(3):R1294-302. PMID: 17652362.
        View in: PubMed
      64. Zhou D, Xue J, Chen J, Morcillo P, Lambert JD, White KP, Haddad G. Experimental selection for Drosophila survival in extremely low O(2) environment. PLoS One. 2007 May 30; 2(5):e490. PMID: 17534440; PMCID: PMC1871610.
      65. Xue J, Zhou D, Yao H, Gavrialov O, McConnell MJ, Gelb BD, Haddad G. Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2406-16. PMID: 17289818.
        View in: PubMed
      66. Huang H, Haddad G. Drosophila dMRP4 regulates responsiveness to O2 deprivation and development under hypoxia. Physiol Genomics. 2007 May 11; 29(3):260-6. PMID: 17284667.
        View in: PubMed
      67. Yao H, Shu Y, Wang J, Brinkman BC, Haddad G. Factors influencing cell fate in the infarct rim. J Neurochem. 2007 Mar; 100(5):1224-33. PMID: 17217421.
        View in: PubMed
      68. Gu XQ, Kanaan A, Yao H, Haddad G. Chronic high-inspired CO2 decreases excitability of mouse hippocampal neurons. J Neurophysiol. 2007 Feb; 97(2):1833-8. PMID: 17202241.
        View in: PubMed
      69. Douglas RM, Miyasaka N, Takahashi K, Latuszek-Barrantes A, Haddad G, Hetherington HP. Chronic intermittent but not constant hypoxia decreases NAA/Cr ratios in neonatal mouse hippocampus and thalamus. Am J Physiol Regul Integr Comp Physiol. 2007 Mar; 292(3):R1254-9. PMID: 17082353.
        View in: PubMed
      70. Li G, Zhou D, Vicencio AG, Ryu J, Xue J, Kanaan A, Gavrialov O, Haddad G. Effect of carbon dioxide on neonatal mouse lung: a genomic approach. J Appl Physiol (1985). 2006 Dec; 101(6):1556-64. PMID: 16888043.
        View in: PubMed
      71. Haddad G. Tolerance to low O2: lessons from invertebrate genetic models. Exp Physiol. 2006 Mar; 91(2):277-82. PMID: 16431936.
        View in: PubMed
      72. Fan C, Iacobas DA, Zhou D, Chen Q, Lai JK, Gavrialov O, Haddad G. Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia. Physiol Genomics. 2005 Aug 11; 22(3):292-307. PMID: 15928208; PMCID: PMC2856928.
      73. Chen L, Rio DC, Haddad G, Ma E. Regulatory role of dADAR in ROS metabolism in Drosophila CNS. Brain Res Mol Brain Res. 2004 Nov 24; 131(1-2):93-100. PMID: 15530657.
        View in: PubMed
      74. Xia S, Yang J, Su Y, Qian J, Ma E, Haddad G. Identification of new targets of Drosophila pre-mRNA adenosine deaminase. Physiol Genomics. 2005 Jan 20; 20(2):195-202. PMID: 15522950.
        View in: PubMed
      75. Chen Q, Haddad G. Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals. J Exp Biol. 2004 Aug; 207(Pt 18):3125-9. PMID: 15299033.
        View in: PubMed
      76. Chen Q, Behar KL, Xu T, Fan C, Haddad G. Expression of Drosophila trehalose-phosphate synthase in HEK-293 cells increases hypoxia tolerance. J Biol Chem. 2003 Dec 05; 278(49):49113-8. PMID: 13129920.
        View in: PubMed
      77. Farahani R, Haddad G. Understanding the molecular responses to hypoxia using Drosophila as a genetic model. Respir Physiol Neurobiol. 2003 May 30; 135(2-3):221-9. PMID: 12809621.
        View in: PubMed
      78. Ma E, Tucker MC, Chen Q, Haddad G. Developmental expression and enzymatic activity of pre-mRNA deaminase in Drosophila melanogaster. Brain Res Mol Brain Res. 2002 Jun 15; 102(1-2):100-4. PMID: 12191498.
        View in: PubMed
      79. Ma E, Haddad G. Slot-blot hybridization in studying gene expression during oxygen deprivation. Methods Mol Biol. 2002; 196:139-45. PMID: 12152192.
        View in: PubMed
      80. Chen Q, Ma E, Behar KL, Xu T, Haddad G. Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J Biol Chem. 2002 Feb 01; 277(5):3274-9. PMID: 11719513.
        View in: PubMed
      Gabriel's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _