Gabriel Haddad

Title(s)Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Developing Diverse Physician-Investigator Leaders for the Future of Child Health
    NIH K12HD105271Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Genetic Mechanisms Regulating Hypoxia Tolerance in the Brain
    NIH R21NS111270Apr 1, 2020 - Mar 31, 2022
    Role: Principal Investigator
    Molecular Basis of Hypoxia-Induced Excessive Erythrocytosis
    NIH R01HL146530Jul 5, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Mechanisms Regulating Tolerance to Oxidative Stress in the Brain
    NIH R21NS101652Mar 1, 2017 - Feb 28, 2019
    Role: Principal Investigator
    Study of iPS cells-derived neural and glial cells from subjects with Monge's disease
    NIH R21NS097899Feb 1, 2017 - Jan 31, 2019
    Role: Principal Investigator
    Endothelin receptors modulate cardiorespiratory function during hypoxia
    NIH R01HL127403Jun 1, 2016 - Feb 29, 2020
    Role: Principal Investigator
    Molecular mechanisms of hypoxia tolerance and susceptibility
    NIH P01HL098053Jul 1, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Resistance to oxidant injury
    NIH R21HL093611Apr 1, 2009 - Mar 31, 2011
    Role: Principal Investigator
    Hypoxia and Consequences: From Molecule to Malady
    NIH R13HL093851Jun 15, 2008 - Jun 14, 2009
    Role: Principal Investigator
    Sleep Mechanisms in Children: Role of Metabolism
    NIH R01HL070919Sep 23, 2002 - Jan 31, 2004
    Role: Principal Investigator
    Roles and mechanisms of Slo and Slack Channels in Brain
    NIH P01NS042202Sep 4, 2001 - Aug 31, 2006
    Role: Co-Investigator
    CYCLICAL HYPOXIA--SUSCEPTIBILITY TO NEURONAL INJURY
    NIH R01HL066327Sep 30, 2000 - Aug 31, 2005
    Role: Principal Investigator
    Molecular basis of cell tolerance to 02 deprivation
    NIH R01NS037756Jan 1, 2000 - Apr 3, 2011
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050May 15, 1997 - Mar 31, 2014
    Role: Co-Investigator
    IONIC &METABOLIC MECHANISMS IN HYPOXIC NEURONAL INJURY
    NIH R01NS035918Jan 1, 1997 - Dec 31, 2000
    Role: Principal Investigator
    Hypoxia in Development;Injury and Adaptation Mechanisms
    NIH P01HD032573Dec 1, 1996 - Jul 31, 2011
    Role: Principal Investigator
    Training in Translational Lung Biology and Pathobiology
    NIH T32HL007778Jul 15, 1994 - Jun 30, 2025
    Role: Principal Investigator
    PRENATAL HYPOXIA--CELLULAR BRAINSTEM MATURATION
    NIH R01HD028940Sep 30, 1991 - Aug 31, 1994
    Role: Principal Investigator
    POSTNATAL MATURATION &MODULATION OF RESPIRATORY NEURONS
    NIH R01HL039924Sep 30, 1987 - Jun 30, 1998
    Role: Principal Investigator
    BRAIN INJURY DUE TO NEONATAL SEIZURE
    NIH R01NS024605Jul 1, 1986 - Jun 30, 1993
    Role: Principal Investigator
    RESPIRATORY MUSCLE TRAINING, METABOLIC &STRUCTURAL BASE
    NIH R01HL034467Jul 1, 1986 - Jun 30, 1990
    Role: Principal Investigator
    ENDORPHINS, SLEEP AND MATURATION OF HYPOXIC RESPONSE
    NIH R01HD015736Jul 1, 1981 - Aug 31, 1995
    Role: Principal Investigator
    MUSCULAR FATIGUE
    NIH R01NS014756Jul 1, 1978 - Dec 31, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Intermittent Hypoxia and Hypercapnia Alter Diurnal Rhythms of Luminal Gut Microbiome and Metabolome. mSystems. 2021 Jun 29; e0011621. Allaband C, Lingaraju A, Martino C, Russell B, Tripathi A, Poulsen O, Dantas Machado AC, Zhou D, Xue J, Elijah E, Malhotra A, Dorrestein PC, Knight R, Haddad GG, Zarrinpar A. PMID: 34184915.
      View in: PubMed   Mentions:
    2. Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia. Front Physiol. 2021; 12:680275. Zhou D, Xue J, Miyamoto Y, Poulsen O, Eckmann L, Haddad GG. PMID: 34248668.
      View in: PubMed   Mentions:
    3. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 May 27. Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. PMID: 34043589.
      View in: PubMed   Mentions:    Fields:    
    4. Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy. Mol Psychiatry. 2021 Apr 22. Negraes PD, Trujillo CA, Yu NK, Wu W, Yao H, Liang N, Lautz JD, Kwok E, McClatchy D, Diedrich J, de Bartolome SM, Truong J, Szeto R, Tran T, Herai RH, Smith SEP, Haddad GG, Yates JR, Muotri AR. PMID: 33888873.
      View in: PubMed   Mentions:    Fields:    
    5. Influence of Intermittent Hypoxia/Hypercapnia on Atherosclerosis, Gut Microbiome, and Metabolome. Front Physiol. 2021; 12:663950. Xue J, Allaband C, Zhou D, Poulsen O, Martino C, Jiang L, Tripathi A, Elijah E, Dorrestein PC, Knight R, Zarrinpar A, Haddad GG. PMID: 33897472.
      View in: PubMed   Mentions:
    6. Multiple mechanisms drive genomic adaptation to extreme O2 levels in Drosophila melanogaster. Nat Commun. 2021 02 12; 12(1):997. Iranmehr A, Stobdan T, Zhou D, Zhao H, Kryazhimskiy S, Bafna V, Haddad GG. PMID: 33579965.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Genetic interactions regulate hypoxia tolerance conferred by activating Notch in excitatory amino acid transporter 1-positive glial cells in Drosophila melanogaster. G3 (Bethesda). 2021 Feb 09; 11(2). Zhou D, Stobdan T, Visk D, Xue J, Haddad GG. PMID: 33576765.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Protective role of estrogen against excessive erythrocytosis in Monge's disease. Exp Mol Med. 2021 Jan; 53(1):125-135. Azad P, Villafuerte FC, Bermudez D, Patel G, Haddad GG. PMID: 33473144.
      View in: PubMed   Mentions:    Fields:    
    9. Neuroprotective Role of Akt in Hypoxia Adaptation in Andeans. Front Neurosci. 2020; 14:607711. Zhao H, Lin J, Sieck G, Haddad GG. PMID: 33519361.
      View in: PubMed   Mentions:
    10. Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids. Front Neurosci. 2020; 14:593248. Wu W, Yao H, Dwivedi I, Negraes PD, Zhao HW, Wang J, Trujillo CA, Muotri AR, Haddad GG. PMID: 33328864.
      View in: PubMed   Mentions:
    11. Methadone interrupts neural growth and function in human cortical organoids. Stem Cell Res. 2020 12; 49:102065. Yao H, Wu W, Cerf I, Zhao HW, Wang J, Negraes PD, Muotri AR, Haddad GG. PMID: 33137567.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Int J Mol Sci. 2020 Mar 15; 21(6). Engelhart DC, Azad P, Ali S, Granados JC, Haddad GG, Nigam SK. PMID: 32183456.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. 2020 03; 579(7797):123-129. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. PMID: 32103176.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    14. Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with chronic mountain sickness. . 2020 01 01; 318(1):R49-R56. Bermudez D, Azad P, Figueroa-Mujíca R, Vizcardo-Galindo G, Corante N, Guerra-Giraldez C, Haddad GG, Villafuerte FC. PMID: 31617751.
      View in: PubMed   Mentions:
    15. Intermittent hypoxia and hypercapnia induces inhibitor of nuclear factor-?B kinase subunit ß-dependent atherosclerosis in pulmonary arteries. Am J Physiol Regul Integr Comp Physiol. 2019 12 01; 317(6):R763-R769. Imamura T, Xue J, Poulsen O, Zhou D, Karin M, Haddad GG. PMID: 31618063.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    16. Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. Cell Stem Cell. 2019 10 03; 25(4):558-569.e7. Trujillo CA, Gao R, Negraes PD, Gu J, Buchanan J, Preissl S, Wang A, Wu W, Haddad GG, Chaim IA, Domissy A, Vandenberghe M, Devor A, Yeo GW, Voytek B, Muotri AR. PMID: 31474560.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    17. Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems. mSystems. 2019 Mar-Apr; 4(2). Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R. PMID: 31058230.
      View in: PubMed   Mentions:
    18. Commentary: Novel Insight into the Genetic Basis of High Altitude Pulmonary Hypertension in Kyrgyz Highlanders. J Lung Health Dis. 2019; 3(2):29-30. Stobdan T, Haddad GG. PMID: 31304480.
      View in: PubMed   Mentions:
    19. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. PLoS One. 2019; 14(3):e0213474. Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG. PMID: 30861021.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    20. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. Am J Hum Genet. 2018 11 01; 103(5):826. Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG. PMID: 30388405.
      View in: PubMed   Mentions: 3     Fields:    
    21. Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlanders. Eur J Hum Genet. 2019 01; 27(1):150-159. Iranmehr A, Stobdan T, Zhou D, Poulsen O, Strohl KP, Aldashev A, Telenti A, Wong EHM, Kirkness EF, Venter JC, Bafna V, Haddad GG. PMID: 30254217.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. Am J Hum Genet. 2018 09 06; 103(3):431-439. Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG. PMID: 30100084.
      View in: PubMed   Mentions: 10     Fields:    
    23. Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia. J Mol Med (Berl). 2018 09; 96(9):975-982. Stobdan T, Zhou D, Williams AT, Cabrales P, Haddad GG. PMID: 30069745.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. Exploring miRNA-mRNA regulatory network in cardiac pathology in Na+/H+ exchanger isoform 1 transgenic mice. Physiol Genomics. 2018 10 01; 50(10):846-861. Xue J, Zhou D, Poulsen O, Hartley I, Imamura T, Xie EX, Haddad GG. PMID: 30029588.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome. mSystems. 2018 May-Jun; 3(3). Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG. PMID: 29896566.
      View in: PubMed   Mentions:
    26. Intracellular pH Regulation in iPSCs-derived Astrocytes from Subjects with Chronic Mountain Sickness. Neuroscience. 2018 04 01; 375:25-33. Yao H, Zhao H, Wang J, Haddad GG. PMID: 29438800.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Down-regulation of Inwardly Rectifying K+ Currents in Astrocytes Derived from Patients with Monge's Disease. Neuroscience. 2018 03 15; 374:70-79. Wu W, Yao H, Zhao HW, Wang J, Haddad GG. PMID: 29355592.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Mitochondrial dysfunction in iPSC-derived neurons of subjects with chronic mountain sickness. J Appl Physiol (1985). 2018 09 01; 125(3):832-840. Zhao H, Perkins G, Yao H, Callacondo D, Appenzeller O, Ellisman M, La Spada AR, Haddad GG. PMID: 29357502.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    29. New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude. Mol Biol Evol. 2017 Dec 01; 34(12):3154-3168. Stobdan T, Akbari A, Azad P, Zhou D, Poulsen O, Appenzeller O, Gonzales GF, Telenti A, Wong EHM, Saini S, Kirkness EF, Venter JC, Bafna V, Haddad GG. PMID: 29029226.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    30. Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide. Am J Respir Cell Mol Biol. 2017 11; 57(5):581-588. Xue J, Zhou D, Poulsen O, Imamura T, Hsiao YH, Smith TH, Malhotra A, Dorrestein P, Knight R, Haddad GG. PMID: 28678519.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    31. High-altitude adaptation in humans: from genomics to integrative physiology. J Mol Med (Berl). 2017 Dec; 95(12):1269-1282. Azad P, Stobdan T, Zhou D, Hartley I, Akbari A, Bafna V, Haddad GG. PMID: 28951950.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    32. Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. J Physiol. 2017 09 01; 595(17):5797-5813. Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. PMID: 28688178.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    33. Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. J Exp Med. 2016 11 14; 213(12):2729-2744. Azad P, Zhao HW, Cabrales PJ, Ronen R, Zhou D, Poulsen O, Appenzeller O, Hsiao YH, Bafna V, Haddad GG. PMID: 27821551.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    34. The Na+/HCO3- co-transporter is protective during ischemia in astrocytes. Neuroscience. 2016 Dec 17; 339:329-337. Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad GG. PMID: 27717805.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    35. Intermittent hypoxia induces murine macrophage foam cell formation by IKK-ß-dependent NF-?B pathway activation. J Appl Physiol (1985). 2016 09 01; 121(3):670-7. Imamura T, Poulsen O, Haddad GG. PMID: 27471237.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    36. Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits. BMC Biol. 2015 Nov 27; 13:101. Aggarwal DD, Rashkovetsky E, Michalak P, Cohen I, Ronin Y, Zhou D, Haddad GG, Korol AB. PMID: 26614097.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    37. Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations. Mol Biol Evol. 2016 Feb; 33(2):501-17. Jha AR, Zhou D, Brown CD, Kreitman M, Haddad GG, White KP. PMID: 26576852.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    38. Cardiac responses to hypoxia and reoxygenation in Drosophila. . 2015 Dec 01; 309(11):R1347-57. Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K. PMID: 26377557.
      View in: PubMed   Mentions:
    39. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):355-67. Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. PMID: 25569851.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    40. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. PMID: 26240367.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    41. Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda). 2015 Apr 03; 5(6):1107-16. Manchenkov T, Pasillas MP, Haddad GG, Imam FB. PMID: 25840431.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. High-throughput cell death assays. Methods Mol Biol. 2015; 1254:153-63. Pamenter ME, Haddad GG. PMID: 25431064.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    43. A Drosophila ABC transporter regulates lifespan. PLoS Genet. 2014 Dec; 10(12):e1004844. Huang H, Lu-Bo Y, Haddad GG. PMID: 25474322.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    44. The genetic basis of chronic mountain sickness. Physiology (Bethesda). 2014 Nov; 29(6):403-12. Ronen R, Zhou D, Bafna V, Haddad GG. PMID: 25362634.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    45. Wnt pathway activation increases hypoxia tolerance during development. PLoS One. 2014; 9(8):e103292. Gersten M, Zhou D, Azad P, Haddad GG, Subramaniam S. PMID: 25093834.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    46. Fine tuning of the UPR by the ubiquitin ligases Siah1/2. PLoS Genet. 2014 May; 10(5):e1004348. Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. PMID: 24809345.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    47. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. BMC Bioinformatics. 2014 Mar 12; 15:69. Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC. PMID: 24621103.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    48. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biol. 2014 Feb 20; 15(2):R36. Udpa N, Ronen R, Zhou D, Liang J, Stobdan T, Appenzeller O, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Claydon VE, Hainsworth R, Gamboa JL, Zibenigus M, Zenebe G, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. PMID: 24555826.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    49. Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma. Glia. 2014 Apr; 62(4):504-13. Gu XQ, Pamenter ME, Siemen D, Sun X, Haddad GG. PMID: 24446243.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    50. Do BK channels mediate glioma hypoxia-tolerance? Channels (Austin). 2014; 8(3):176-7. Pamenter ME, Haddad GG. PMID: 24813649.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Hematopoietic stem cells: potential new applications for translational medicine. J Stem Cells. 2014; 9(3):163-97. Felfly H, Haddad GG. PMID: 25157450.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    52. Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures. PLoS One. 2013; 8(10):e77859. Hartley I, Elkhoury FF, Heon Shin J, Xie B, Gu X, Gao Y, Zhou D, Haddad GG. PMID: 24205000.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    53. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab. 2014 Feb; 3(1):42-54. Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG. PMID: 24567903.
      View in: PubMed   Mentions: 27     Fields:    
    54. Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions. PLoS One. 2013; 8(9):e74011. Yin S, Xue J, Sun H, Wen B, Wang Q, Perkins G, Zhao HW, Ellisman MH, Hsiao YH, Yin L, Xie Y, Hou G, Zi J, Lin L, Haddad GG, Zhou D, Liu S. PMID: 24069262.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    55. Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985). 2013 Dec; 115(11):1694-704. Douglas RM, Bowden K, Pattison J, Peterson AB, Juliano J, Dalton ND, Gu Y, Alvarez E, Imamura T, Peterson KL, Witztum JL, Haddad GG, Li AC. PMID: 23990245.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    56. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 05; 93(3):452-62. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. PMID: 23954164.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    57. Genetic analysis of hypoxia tolerance and susceptibility in Drosophila and humans. Annu Rev Genomics Hum Genet. 2013; 14:25-43. Zhou D, Haddad GG. PMID: 23808366.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
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