Loading...

Gabriel Haddad

Title(s)Adjunct Professor, Neurosciences
SchoolHealth Sciences
Phone858-822-4740
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Basis of Hypoxia-Induced Excessive Erythrocytosis
    NIH/NHLBI R01HL146530Jul 5, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Mechanisms Regulating Tolerance to Oxidative Stress in the Brain
    NIH/NINDS R21NS101652Mar 1, 2017 - Feb 28, 2019
    Role: Principal Investigator
    Study of iPS cells-derived neural and glial cells from subjects with Monge's disease
    NIH/NINDS R21NS097899Feb 1, 2017 - Jan 31, 2019
    Role: Principal Investigator
    Endothelin receptors modulate cardiorespiratory function during hypoxia
    NIH/NHLBI R01HL127403Jun 1, 2016 - Feb 29, 2020
    Role: Principal Investigator
    Molecular mechanisms of hypoxia tolerance and susceptibility
    NIH/NHLBI P01HL098053Jul 1, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Resistance to oxidant injury
    NIH/NHLBI R21HL093611Apr 1, 2009 - Mar 31, 2011
    Role: Principal Investigator
    Hypoxia and Consequences: From Molecule to Malady
    NIH/NHLBI R13HL093851Jun 15, 2008 - Jun 14, 2009
    Role: Principal Investigator
    Sleep Mechanisms in Children: Role of Metabolism
    NIH/NHLBI R01HL070919Sep 23, 2002 - Jan 31, 2004
    Role: Principal Investigator
    Roles and mechanisms of Slo and Slack Channels in Brain
    NIH P01NS042202Sep 4, 2001 - Aug 31, 2006
    Role: Co-Investigator
    CYCLICAL HYPOXIA--SUSCEPTIBILITY TO NEURONAL INJURY
    NIH/NHLBI R01HL066327Sep 30, 2000 - Aug 31, 2005
    Role: Principal Investigator
    Molecular basis of cell tolerance to 02 deprivation
    NIH/NINDS R01NS037756Jan 1, 2000 - Apr 3, 2011
    Role: Principal Investigator
    IONIC &METABOLIC MECHANISMS IN HYPOXIC NEURONAL INJURY
    NIH/NINDS R01NS035918Jan 1, 1997 - Dec 31, 2000
    Role: Principal Investigator
    Hypoxia in Development;Injury and Adaptation Mechanisms
    NIH/NICHD P01HD032573Feb 10, 1995 - Jul 31, 2011
    Role: Principal Investigator
    Training in Translational Lung Biology and Pathobiology
    NIH/NHLBI T32HL007778Jul 15, 1994 - Jun 30, 2020
    Role: Principal Investigator
    PRENATAL HYPOXIA--CELLULAR BRAINSTEM MATURATION
    NIH/NICHD R01HD028940Sep 30, 1991 - Aug 31, 1994
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    POSTNATAL MATURATION &MODULATION OF RESPIRATORY NEURONS
    NIH/NHLBI R01HL039924Sep 30, 1987 - Jun 30, 1998
    Role: Principal Investigator
    BRAIN INJURY DUE TO NEONATAL SEIZURE
    NIH/NINDS R01NS024605Jul 1, 1986 - Jun 30, 1993
    Role: Principal Investigator
    RESPIRATORY MUSCLE TRAINING, METABOLIC &STRUCTURAL BASE
    NIH/NHLBI R01HL034467Jul 1, 1986 - Jun 30, 1990
    Role: Principal Investigator
    ENDORPHINS, SLEEP AND MATURATION OF HYPOXIC RESPONSE
    NIH/NICHD R01HD015736Jul 1, 1981 - Aug 31, 1995
    Role: Principal Investigator
    MUSCULAR FATIGUE
    NIH/NINDS R01NS014756Jul 1, 1978 - Dec 31, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Imamura T, Xue J, Poulsen O, Zhou D, Karin M, Haddad GG. Intermittent Hypoxia and Hypercapnia Induces Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta-dependent Atherosclerosis in Pulmonary Arteries. Am J Physiol Regul Integr Comp Physiol. 2019 Oct 16. PMID: 31618063.
      View in: PubMed
    2. Bermudez D, Azad P, Figueroa-Mujíca R, Vizcardo-Galindo G, Corante N, Guerra-Giraldez C, Haddad GG, Villafuerte FC. Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with Chronic Mountain Sickness. Am J Physiol Regul Integr Comp Physiol. 2019 10 16. PMID: 31617751.
      View in: PubMed
    3. Trujillo CA, Gao R, Negraes PD, Gu J, Buchanan J, Preissl S, Wang A, Wu W, Haddad GG, Chaim IA, Domissy A, Vandenberghe M, Devor A, Yeo GW, Voytek B, Muotri AR. Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. Cell Stem Cell. 2019 Oct 03; 25(4):558-569.e7. PMID: 31474560.
      View in: PubMed
    4. Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R. Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems. mSystems. 2019 Mar-Apr; 4(2). PMID: 31058230.
      View in: PubMed
    5. Stobdan T, Haddad GG. Commentary: Novel Insight into the Genetic Basis of High Altitude Pulmonary Hypertension in Kyrgyz Highlanders. J Lung Health Dis. 2019; 3(2):29-30. PMID: 31304480.
      View in: PubMed
    6. Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. PLoS One. 2019; 14(3):e0213474. PMID: 30861021.
      View in: PubMed
    7. Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. Am J Hum Genet. 2018 11 01; 103(5):826. PMID: 30388405.
      View in: PubMed
    8. Iranmehr A, Stobdan T, Zhou D, Poulsen O, Strohl KP, Aldashev A, Telenti A, Wong EHM, Kirkness EF, Venter JC, Bafna V, Haddad GG. Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlanders. Eur J Hum Genet. 2019 01; 27(1):150-159. PMID: 30254217.
      View in: PubMed
    9. Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG. Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome. Am J Hum Genet. 2018 09 06; 103(3):431-439. PMID: 30100084.
      View in: PubMed
    10. Stobdan T, Zhou D, Williams AT, Cabrales P, Haddad GG. Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia. J Mol Med (Berl). 2018 09; 96(9):975-982. PMID: 30069745.
      View in: PubMed
    11. Xue J, Zhou D, Poulsen O, Hartley I, Imamura T, Xie EX, Haddad GG. Exploring miRNA-mRNA regulatory network in cardiac pathology in Na+/H+ exchanger isoform 1 transgenic mice. Physiol Genomics. 2018 10 01; 50(10):846-861. PMID: 30029588.
      View in: PubMed
    12. Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG. Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome. mSystems. 2018 May-Jun; 3(3). PMID: 29896566.
      View in: PubMed
    13. Yao H, Zhao H, Wang J, Haddad GG. Intracellular pH Regulation in iPSCs-derived Astrocytes from Subjects with Chronic Mountain Sickness. Neuroscience. 2018 04 01; 375:25-33. PMID: 29438800.
      View in: PubMed
    14. Wu W, Yao H, Zhao HW, Wang J, Haddad GG. Down-regulation of Inwardly Rectifying K+ Currents in Astrocytes Derived from Patients with Monge's Disease. Neuroscience. 2018 03 15; 374:70-79. PMID: 29355592.
      View in: PubMed
    15. Zhao H, Perkins G, Yao H, Callacondo D, Appenzeller O, Ellisman M, La Spada AR, Haddad GG. Mitochondrial dysfunction in iPSC-derived neurons of subjects with chronic mountain sickness. J Appl Physiol (1985). 2018 09 01; 125(3):832-840. PMID: 29357502.
      View in: PubMed
    16. Stobdan T, Akbari A, Azad P, Zhou D, Poulsen O, Appenzeller O, Gonzales GF, Telenti A, Wong EHM, Saini S, Kirkness EF, Venter JC, Bafna V, Haddad GG. New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude. Mol Biol Evol. 2017 Dec 01; 34(12):3154-3168. PMID: 29029226.
      View in: PubMed
    17. Xue J, Zhou D, Poulsen O, Imamura T, Hsiao YH, Smith TH, Malhotra A, Dorrestein P, Knight R, Haddad GG. Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide. Am J Respir Cell Mol Biol. 2017 11; 57(5):581-588. PMID: 28678519.
      View in: PubMed
    18. Azad P, Stobdan T, Zhou D, Hartley I, Akbari A, Bafna V, Haddad GG. High-altitude adaptation in humans: from genomics to integrative physiology. J Mol Med (Berl). 2017 Dec; 95(12):1269-1282. PMID: 28951950.
      View in: PubMed
    19. Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. J Physiol. 2017 09 01; 595(17):5797-5813. PMID: 28688178.
      View in: PubMed
    20. Azad P, Zhao HW, Cabrales PJ, Ronen R, Zhou D, Poulsen O, Appenzeller O, Hsiao YH, Bafna V, Haddad GG. Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. J Exp Med. 2016 11 14; 213(12):2729-2744. PMID: 27821551.
      View in: PubMed
    21. Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad GG. The Na+/HCO3- co-transporter is protective during ischemia in astrocytes. Neuroscience. 2016 Dec 17; 339:329-337. PMID: 27717805.
      View in: PubMed
    22. Imamura T, Poulsen O, Haddad GG. Intermittent hypoxia induces murine macrophage foam cell formation by IKK-ß-dependent NF-?B pathway activation. J Appl Physiol (1985). 2016 09 01; 121(3):670-7. PMID: 27471237.
      View in: PubMed
    23. Aggarwal DD, Rashkovetsky E, Michalak P, Cohen I, Ronin Y, Zhou D, Haddad GG, Korol AB. Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits. BMC Biol. 2015 Nov 27; 13:101. PMID: 26614097.
      View in: PubMed
    24. Jha AR, Zhou D, Brown CD, Kreitman M, Haddad GG, White KP. Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations. Mol Biol Evol. 2016 Feb; 33(2):501-17. PMID: 26576852.
      View in: PubMed
    25. Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K. Cardiac responses to hypoxia and reoxygenation in Drosophila. Am J Physiol Regul Integr Comp Physiol. 2015 Dec 01; 309(11):R1347-57. PMID: 26377557.
      View in: PubMed
    26. Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):355-67. PMID: 25569851.
      View in: PubMed
    27. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. PMID: 26240367.
      View in: PubMed
    28. Manchenkov T, Pasillas MP, Haddad GG, Imam FB. Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda). 2015 Apr 03; 5(6):1107-16. PMID: 25840431.
      View in: PubMed
    29. Zhao HW, Gu XQ, Chailangkarn T, Perkins G, Callacondo D, Appenzeller O, Poulsen O, Zhou D, Muotri AR, Haddad GG. Altered iPSC-derived neurons' sodium channel properties in subjects with Monge's disease. Neuroscience. 2015 Mar 12; 288:187-99. PMID: 25559931.
      View in: PubMed
    30. Pamenter ME, Haddad GG. High-throughput cell death assays. Methods Mol Biol. 2015; 1254:153-63. PMID: 25431064.
      View in: PubMed
    31. Huang H, Lu-Bo Y, Haddad GG. A Drosophila ABC transporter regulates lifespan. PLoS Genet. 2014 Dec; 10(12):e1004844. PMID: 25474322.
      View in: PubMed
    32. Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry. 2015 Nov; 20(11):1350-65. PMID: 25385366.
      View in: PubMed
    33. Ronen R, Zhou D, Bafna V, Haddad GG. The genetic basis of chronic mountain sickness. Physiology (Bethesda). 2014 Nov; 29(6):403-12. PMID: 25362634.
      View in: PubMed
    34. Gersten M, Zhou D, Azad P, Haddad GG, Subramaniam S. Wnt pathway activation increases hypoxia tolerance during development. PLoS One. 2014; 9(8):e103292. PMID: 25093834.
      View in: PubMed
    35. Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. Fine tuning of the UPR by the ubiquitin ligases Siah1/2. PLoS Genet. 2014 May; 10(5):e1004348. PMID: 24809345.
      View in: PubMed
    36. Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. BMC Bioinformatics. 2014 Mar 12; 15:69. PMID: 24621103.
      View in: PubMed
    37. Udpa N, Ronen R, Zhou D, Liang J, Stobdan T, Appenzeller O, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Claydon VE, Hainsworth R, Gamboa JL, Zibenigus M, Zenebe G, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes. Genome Biol. 2014 Feb 20; 15(2):R36. PMID: 24555826.
      View in: PubMed
    38. Gu XQ, Pamenter ME, Siemen D, Sun X, Haddad GG. Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma. Glia. 2014 Apr; 62(4):504-13. PMID: 24446243.
      View in: PubMed
    39. Pamenter ME, Haddad GG. Do BK channels mediate glioma hypoxia-tolerance? Channels (Austin). 2014; 8(3):176-7. PMID: 24813649.
      View in: PubMed
    40. Felfly H, Haddad GG. Hematopoietic stem cells: potential new applications for translational medicine. J Stem Cells. 2014; 9(3):163-97. PMID: 25157450.
      View in: PubMed
    41. Hartley I, Elkhoury FF, Heon Shin J, Xie B, Gu X, Gao Y, Zhou D, Haddad GG. Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures. PLoS One. 2013; 8(10):e77859. PMID: 24205000.
      View in: PubMed
    42. Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Mol Metab. 2014 Feb; 3(1):42-54. PMID: 24567903.
      View in: PubMed
    43. Yin S, Xue J, Sun H, Wen B, Wang Q, Perkins G, Zhao HW, Ellisman MH, Hsiao YH, Yin L, Xie Y, Hou G, Zi J, Lin L, Haddad GG, Zhou D, Liu S. Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions. PLoS One. 2013; 8(9):e74011. PMID: 24069262.
      View in: PubMed
    44. Douglas RM, Bowden K, Pattison J, Peterson AB, Juliano J, Dalton ND, Gu Y, Alvarez E, Imamura T, Peterson KL, Witztum JL, Haddad GG, Li AC. Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985). 2013 Dec; 115(11):1694-704. PMID: 23990245.
      View in: PubMed
    45. Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG. Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet. 2013 Sep 05; 93(3):452-62. PMID: 23954164.
      View in: PubMed
    46. Zhou D, Haddad GG. Genetic analysis of hypoxia tolerance and susceptibility in Drosophila and humans. Annu Rev Genomics Hum Genet. 2013; 14:25-43. PMID: 23808366.
      View in: PubMed
    47. Xie L, Ng C, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad GG, Bourne PE, Xie L. Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia. BMC Genomics. 2013; 14 Suppl 3:S9. PMID: 23819581.
      View in: PubMed
    48. Pamenter ME, Perkins GA, Gu XQ, Ellisman MH, Haddad GG. DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress. PLoS One. 2013; 8(4):e60804. PMID: 23577164.
      View in: PubMed
    49. Sieck GC, Haddad GG, Lucchesi P. Physiology's impact: discovering life. Physiology (Bethesda). 2013 Mar; 28(2):62-3. PMID: 23455765.
      View in: PubMed
    50. Douglas RM, Chen AH, Iniguez A, Wang J, Fu Z, Powell FL, Haddad GG, Yao H. Chemokine receptor-like 2 is involved in ischemic brain injury. J Exp Stroke Transl Med. 2013 Feb 17; 6:1-6. PMID: 23847708.
      View in: PubMed
    51. Pamenter ME, Perkins GA, McGinness AK, Gu XQ, Ellisman MH, Haddad GG. Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra. PLoS One. 2012; 7(12):e51469. PMID: 23251543.
      View in: PubMed
    52. Azad P, Haddad GG. Genetic animal models of preconditioning. Transl Stroke Res. 2013 Feb; 4(1):51-5. PMID: 23565128.
      View in: PubMed
    53. Azad P, Zhou D, Zarndt R, Haddad GG. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. G3 (Bethesda). 2012 Oct; 2(10):1169-78. PMID: 23050227.
      View in: PubMed
    54. Ryu J, Haddad G, Carlo WA. Clinical effectiveness and safety of permissive hypercapnia. Clin Perinatol. 2012 Sep; 39(3):603-12. PMID: 22954272.
      View in: PubMed
    55. Kinney HC, Rognum TO, Nattie EE, Haddad GG, Hyma B, McEntire B, Paterson DS, Crandall L, Byard RW. Sudden and unexpected death in early life: proceedings of a symposium in honor of Dr. Henry F. Krous. Forensic Sci Med Pathol. 2012 Dec; 8(4):414-25. PMID: 22941540.
      View in: PubMed
    56. Pamenter ME, Ryu J, Hua ST, Perkins GA, Mendiola VL, Gu XQ, Ellisman MH, Haddad GG. DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release. PLoS One. 2012; 7(8):e43995. PMID: 22937143.
      View in: PubMed
    57. Heinrichsen ET, Haddad GG. Role of high-fat diet in stress response of Drosophila. PLoS One. 2012; 7(8):e42587. PMID: 22870336.
      View in: PubMed
    58. Pamenter ME, Hogg DW, Gu XQ, Buck LT, Haddad GG. Painted turtle cortex is resistant to an in vitro mimic of the ischemic mammalian penumbra. J Cereb Blood Flow Metab. 2012 Nov; 32(11):2033-43. PMID: 22805876.
      View in: PubMed
    59. Lesser DJ, Haddad GG, Bush RA, Pian MS. The utility of a portable recording device for screening of obstructive sleep apnea in obese adolescents. J Clin Sleep Med. 2012 Jun 15; 8(3):271-7. PMID: 22701384.
      View in: PubMed
    60. Ali SS, Hsiao M, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. PLoS One. 2012; 7(5):e36801. PMID: 22574227.
      View in: PubMed
    61. Pamenter ME, Ali SS, Tang Q, Finley JC, Gu XQ, Dugan LL, Haddad GG. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Res. 2012 May 03; 1452:165-72. PMID: 22459046.
      View in: PubMed
    62. Zhao HW, Ali SS, Haddad GG. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transport chain activity leading to a reduction of superoxide production? Antioxid Redox Signal. 2012 May 15; 16(10):1071-6. PMID: 22229946.
      View in: PubMed
    63. Mittal M, Gu XQ, Pak O, Pamenter ME, Haag D, Fuchs DB, Schermuly RT, Ghofrani HA, Brandes RP, Seeger W, Grimminger F, Haddad GG, Weissmann N. Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species. Free Radic Biol Med. 2012 Mar 15; 52(6):1033-42. PMID: 22222468.
      View in: PubMed
    64. Udpa N, Zhou D, Haddad GG, Bafna V. Tests of selection in pooled case-control data: an empirical study. Front Genet. 2011; 2:83. PMID: 22303377.
      View in: PubMed
    65. Haddad GG. Does the brain gain back energy during sleep? But what does it mean? Sleep. 2011 Jul 01; 34(7):835-6. PMID: 21731130.
      View in: PubMed
    66. Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad GG. Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro. Am J Physiol Regul Integr Comp Physiol. 2011 Sep; 301(3):R727-45. PMID: 21677276.
      View in: PubMed
    67. Azad P, Ryu J, Haddad GG. Distinct role of Hsp70 in Drosophila hemocytes during severe hypoxia. Free Radic Biol Med. 2011 Jul 15; 51(2):530-8. PMID: 21616137.
      View in: PubMed
    68. Zhao HW, Haddad GG. Review: Hypoxic and oxidative stress resistance in Drosophila melanogaster. Placenta. 2011 Mar; 32 Suppl 2:S104-8. PMID: 21353099.
      View in: PubMed
    69. Zhou D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer KA, Posakony JW, Subramaniam S, Bafna V, Haddad GG. Experimental selection of hypoxia-tolerant Drosophila melanogaster. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2349-54. PMID: 21262834.
      View in: PubMed
    70. Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad GG. Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. J Neurol Res. 2011; 1(5). PMID: 24348887.
      View in: PubMed
    71. Harrison JF, Haddad GG. Effects of oxygen on growth and size: synthesis of molecular, organismal, and evolutionary studies with Drosophila melanogaster. Annu Rev Physiol. 2011; 73:95-113. PMID: 20936942.
      View in: PubMed
    72. Zhao HW, Zhou D, Haddad GG. Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. J Biol Chem. 2011 Feb 25; 286(8):6211-8. PMID: 21148307.
      View in: PubMed
    73. Zhao HW, Zhou D, Nizet V, Haddad GG. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010 Jul 23; 5(7):e11701. PMID: 20668515.
      View in: PubMed
    74. Felfly H, Muotri A, Yao H, Haddad GG. Hematopoietic stem cell transplantation protects mice from lethal stroke. Exp Neurol. 2010 Oct; 225(2):284-93. PMID: 20547154.
      View in: PubMed
    75. Xue J, Mraiche F, Zhou D, Karmazyn M, Oka T, Fliegel L, Haddad GG. Elevated myocardial Na+/H+ exchanger isoform 1 activity elicits gene expression that leads to cardiac hypertrophy. Physiol Genomics. 2010 Aug; 42(3):374-83. PMID: 20460605.
      View in: PubMed
    76. Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F, Johnson RS. The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metab. 2010 May 05; 11(5):364-78. PMID: 20399150.
      View in: PubMed
    77. Ryu J, Heldt GP, Nguyen M, Gavrialov O, Haddad GG. Chronic hypercapnia alters lung matrix composition in mouse pups. J Appl Physiol (1985). 2010 Jul; 109(1):203-10. PMID: 20360436.
      View in: PubMed
    78. Douglas RM, Ryu J, Kanaan A, Del Carmen Rivero M, Dugan LL, Haddad GG, Ali SS. Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. Am J Physiol Cell Physiol. 2010 Jun; 298(6):C1594-602. PMID: 20357179.
      View in: PubMed
    79. Iacobas DA, Iacobas S, Haddad GG. Heart rhythm genomic fabric in hypoxia. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1769-74. PMID: 20044980.
      View in: PubMed
    80. Sun X, Yao H, Douglas RM, Gu XQ, Wang J, Haddad GG. Insulin/PI3K signaling protects dentate neurons from oxygen-glucose deprivation in organotypic slice cultures. J Neurochem. 2010 Jan; 112(2):377-88. PMID: 19860861.
      View in: PubMed
    81. Demory ML, Boerner JL, Davidson R, Faust W, Miyake T, Lee I, Hüttemann M, Douglas R, Haddad G, Parsons SJ. Epidermal growth factor receptor translocation to the mitochondria: regulation and effect. J Biol Chem. 2009 Dec 25; 284(52):36592-604. PMID: 19840943.
      View in: PubMed
    82. Azad P, Haddad GG. Survival in acute and severe low o environment: use of a genetic model system. Ann N Y Acad Sci. 2009 Oct; 1177:39-47. PMID: 19845605.
      View in: PubMed
    83. Feala JD, Coquin L, Zhou D, Haddad GG, Paternostro G, McCulloch AD. Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis. BMC Syst Biol. 2009 Sep 09; 3:91. PMID: 19740440.
      View in: PubMed
    84. Zhou D, Visk DW, Haddad GG. Drosophila, a golden bug, for the dissection of the genetic basis of tolerance and susceptibility to hypoxia. Pediatr Res. 2009 Sep; 66(3):239-47. PMID: 19542900.
      View in: PubMed
    85. Guma M, Rius J, Duong-Polk KX, Haddad GG, Lindsey JD, Karin M. Genetic and pharmacological inhibition of JNK ameliorates hypoxia-induced retinopathy through interference with VEGF expression. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8760-5. PMID: 19433784.
      View in: PubMed
    86. Azad P, Zhou D, Russo E, Haddad GG. Distinct mechanisms underlying tolerance to intermittent and constant hypoxia in Drosophila melanogaster. PLoS One. 2009; 4(4):e5371. PMID: 19401761.
      View in: PubMed
    87. Yao H, Felfly H, Wang J, Zhou D, Haddad GG. DIDS protects against neuronal injury by blocking Toll-like receptor 2 activated-mechanisms. J Neurochem. 2009 Feb; 108(3):835-46. PMID: 19077053.
      View in: PubMed
    88. Douglas RM, Haddad GG. Can O2 dysregulation induce premature aging? Physiology (Bethesda). 2008 Dec; 23:333-49. PMID: 19074741.
      View in: PubMed
    89. Zhou D, Xue J, Lai JC, Schork NJ, White KP, Haddad GG. Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet. 2008 Oct; 4(10):e1000221. PMID: 18927626.
      View in: PubMed
    90. Chen LM, Haddad GG, Boron WF. Effects of chronic continuous hypoxia on the expression of SLC4A8 (NDCBE) in neonatal versus adult mouse brain. Brain Res. 2008 Oct 31; 1238:85-92. PMID: 18775686.
      View in: PubMed
    91. Cheng Y, Gu XQ, Bednarczyk P, Wiedemann FR, Haddad GG, Siemen D. Hypoxia increases activity of the BK-channel in the inner mitochondrial membrane and reduces activity of the permeability transition pore. Cell Physiol Biochem. 2008; 22(1-4):127-36. PMID: 18769039.
      View in: PubMed
    92. Iacobas DA, Fan C, Iacobas S, Haddad GG. Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival. Funct Integr Genomics. 2008 Aug; 8(3):265-75. PMID: 18446526.
      View in: PubMed
    93. Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 2008 Jun 05; 453(7196):807-11. PMID: 18432192.
      View in: PubMed
    94. Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 2008 Apr 18; 133(2):223-34. PMID: 18423195.
      View in: PubMed
    95. Farahani R, Kanaan A, Gavrialov O, Brunnert S, Douglas RM, Morcillo P, Haddad GG. Differential effects of chronic intermittent and chronic constant hypoxia on postnatal growth and development. Pediatr Pulmonol. 2008 Jan; 43(1):20-8. PMID: 18041750.
      View in: PubMed
    96. Alejandre-Alcázar MA, Michiels-Corsten M, Vicencio AG, Reiss I, Ryu J, de Krijger RR, Haddad GG, Tibboel D, Seeger W, Eickelberg O, Morty RE. TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn. 2008 Jan; 237(1):259-69. PMID: 18095342.
      View in: PubMed
    97. Zhou D, Wang J, Zapala MA, Xue J, Schork NJ, Haddad GG. Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death. Physiol Genomics. 2008 Feb 19; 32(3):370-9. PMID: 18056785.
      View in: PubMed
    98. Sun X, Yao H, Zhou D, Gu X, Haddad GG. Modulation of hSlo BK current inactivation by fatty acid esters of CoA. J Neurochem. 2008 Mar; 104(5):1394-403. PMID: 18005338.
      View in: PubMed
    99. Ruffin VA, Gu XQ, Zhou D, Douglas RM, Sun X, Trouth CO, Haddad GG. The sodium-activated potassium channel Slack is modulated by hypercapnia and acidosis. Neuroscience. 2008 Jan 24; 151(2):410-8. PMID: 18082331.
      View in: PubMed
    100. Xue J, Zhou D, Yao H, Haddad GG. Role of transporters and ion channels in neuronal injury under hypoxia. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R451-7. PMID: 17977915.
      View in: PubMed
    101. Chen LM, Choi I, Haddad GG, Boron WF. Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain. Am J Physiol Regul Integr Comp Physiol. 2007 Dec; 293(6):R2412-20. PMID: 17928512.
      View in: PubMed
    102. Yao H, Sun X, Gu X, Wang J, Haddad GG. Cell death in an ischemic infarct rim model. J Neurochem. 2007 Nov; 103(4):1644-53. PMID: 17727626.
      View in: PubMed
    103. Kanaan A, Douglas RM, Alper SL, Boron WF, Haddad GG. Effect of chronic elevated carbon dioxide on the expression of acid-base transporters in the neonatal and adult mouse. Am J Physiol Regul Integr Comp Physiol. 2007 Sep; 293(3):R1294-302. PMID: 17652362.
      View in: PubMed
    104. Zhou D, Xue J, Chen J, Morcillo P, Lambert JD, White KP, Haddad GG. Experimental selection for Drosophila survival in extremely low O(2) environment. PLoS One. 2007 May 30; 2(5):e490. PMID: 17534440.
      View in: PubMed
    105. Gu XQ, Siemen D, Parvez S, Cheng Y, Xue J, Zhou D, Sun X, Jonas EA, Haddad GG. Hypoxia increases BK channel activity in the inner mitochondrial membrane. Biochem Biophys Res Commun. 2007 Jun 22; 358(1):311-6. PMID: 17481584.
      View in: PubMed
    106. Scafidi S, Douglas RM, Farahani R, Banasiak KJ, Haddad GG. Prostaglandin transporter expression in mouse brain during development and in response to hypoxia. Neuroscience. 2007 May 25; 146(3):1150-7. PMID: 17428614.
      View in: PubMed
    107. Xue J, Zhou D, Yao H, Gavrialov O, McConnell MJ, Gelb BD, Haddad GG. Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2406-16. PMID: 17289818.
      View in: PubMed
    108. Huang H, Haddad GG. Drosophila dMRP4 regulates responsiveness to O2 deprivation and development under hypoxia. Physiol Genomics. 2007 May 11; 29(3):260-6. PMID: 17284667.
      View in: PubMed
    109. Yao H, Shu Y, Wang J, Brinkman BC, Haddad GG. Factors influencing cell fate in the infarct rim. J Neurochem. 2007 Mar; 100(5):1224-33. PMID: 17217421.
      View in: PubMed
    110. Gu XQ, Kanaan A, Yao H, Haddad GG. Chronic high-inspired CO2 decreases excitability of mouse hippocampal neurons. J Neurophysiol. 2007 Feb; 97(2):1833-8. PMID: 17202241.
      View in: PubMed
    111. Douglas RM, Miyasaka N, Takahashi K, Latuszek-Barrantes A, Haddad GG, Hetherington HP. Chronic intermittent but not constant hypoxia decreases NAA/Cr ratios in neonatal mouse hippocampus and thalamus. Am J Physiol Regul Integr Comp Physiol. 2007 Mar; 292(3):R1254-9. PMID: 17082353.
      View in: PubMed
    112. Sun X, Zhou D, Zhang P, Moczydlowski EG, Haddad GG. Beta-subunit-dependent modulation of hSlo BK current by arachidonic acid. J Neurophysiol. 2007 Jan; 97(1):62-9. PMID: 17021030.
      View in: PubMed
    113. Iacobas DA, Fan C, Iacobas S, Spray DC, Haddad GG. Transcriptomic changes in developing kidney exposed to chronic hypoxia. Biochem Biophys Res Commun. 2006 Oct 13; 349(1):329-38. PMID: 16934745.
      View in: PubMed
    114. Li G, Zhou D, Vicencio AG, Ryu J, Xue J, Kanaan A, Gavrialov O, Haddad GG. Effect of carbon dioxide on neonatal mouse lung: a genomic approach. J Appl Physiol (1985). 2006 Dec; 101(6):1556-64. PMID: 16888043.
      View in: PubMed
    115. Douglas RM, Lai JC, Bian S, Cummins L, Moczydlowski E, Haddad GG. The calcium-sensitive large-conductance potassium channel (BK/MAXI K) is present in the inner mitochondrial membrane of rat brain. Neuroscience. 2006; 139(4):1249-61. PMID: 16567053.
      View in: PubMed
    116. Haddad GG. Tolerance to low O2: lessons from invertebrate genetic models. Exp Physiol. 2006 Mar; 91(2):277-82. PMID: 16431936.
      View in: PubMed
    117. Kanaan A, Farahani R, Douglas RM, Lamanna JC, Haddad GG. Effect of chronic continuous or intermittent hypoxia and reoxygenation on cerebral capillary density and myelination. Am J Physiol Regul Integr Comp Physiol. 2006 Apr; 290(4):R1105-14. PMID: 16322350.
      View in: PubMed
    118. Ryu J, Vicencio AG, Yeager ME, Kashgarian M, Haddad GG, Eickelberg O. Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development. Thromb Haemost. 2005 Jul; 94(1):175-83. PMID: 16113801.
      View in: PubMed
    119. Zhao P, Xue J, Gu XQ, Haddad GG, Xia Y. Intermittent hypoxia modulates Na+ channel expression in developing mouse brain. Int J Dev Neurosci. 2005 Jun; 23(4):327-33. PMID: 15927756.
      View in: PubMed
    120. Fan C, Iacobas DA, Zhou D, Chen Q, Lai JK, Gavrialov O, Haddad GG. Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia. Physiol Genomics. 2005 Aug 11; 22(3):292-307. PMID: 15928208.
      View in: PubMed
    121. Chen L, Rio DC, Haddad GG, Ma E. Regulatory role of dADAR in ROS metabolism in Drosophila CNS. Brain Res Mol Brain Res. 2004 Nov 24; 131(1-2):93-100. PMID: 15530657.
      View in: PubMed
    122. Xia S, Yang J, Su Y, Qian J, Ma E, Haddad GG. Identification of new targets of Drosophila pre-mRNA adenosine deaminase. Physiol Genomics. 2005 Jan 20; 20(2):195-202. PMID: 15522950.
      View in: PubMed
    123. Douglas RM, Farahani R, Morcillo P, Kanaan A, Xu T, Haddad GG. Hypoxia induces major effects on cell cycle kinetics and protein expression in Drosophila melanogaster embryos. Am J Physiol Regul Integr Comp Physiol. 2005 Feb; 288(2):R511-21. PMID: 15498965.
      View in: PubMed
    124. Yao H, Haddad GG. Calcium and pH homeostasis in neurons during hypoxia and ischemia. Cell Calcium. 2004 Sep-Oct; 36(3-4):247-55. PMID: 15261480.
      View in: PubMed
    125. Vicencio AG, Lee CG, Cho SJ, Eickelberg O, Chuu Y, Haddad GG, Elias JA. Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol. 2004 Dec; 31(6):650-6. PMID: 15333328.
      View in: PubMed
    126. Zhou D, Xue J, Gavrialov O, Haddad GG. Na+/H+ exchanger 1 deficiency alters gene expression in mouse brain. Physiol Genomics. 2004 Aug 11; 18(3):331-9. PMID: 15306696.
      View in: PubMed
    127. Chen Q, Haddad GG. Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals. J Exp Biol. 2004 Aug; 207(Pt 18):3125-9. PMID: 15299033.
      View in: PubMed
    128. Gu XQ, Xue J, Haddad GG. Effect of chronically elevated CO2 on CA1 neuronal excitability. Am J Physiol Cell Physiol. 2004 Sep; 287(3):C691-7. PMID: 15115704.
      View in: PubMed
    129. Banasiak KJ, Burenkova O, Haddad GG. Activation of voltage-sensitive sodium channels during oxygen deprivation leads to apoptotic neuronal death. Neuroscience. 2004; 126(1):31-44. PMID: 15145071.
      View in: PubMed
    130. Kuan CY, Whitmarsh AJ, Yang DD, Liao G, Schloemer AJ, Dong C, Bao J, Banasiak KJ, Haddad GG, Flavell RA, Davis RJ, Rakic P. A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15184-9. PMID: 14657393.
      View in: PubMed
    131. Chen Q, Behar KL, Xu T, Fan C, Haddad GG. Expression of Drosophila trehalose-phosphate synthase in HEK-293 cells increases hypoxia tolerance. J Biol Chem. 2003 Dec 05; 278(49):49113-8. PMID: 13129920.
      View in: PubMed
    132. Lai JC, White BK, Buerstatte CR, Haddad GG, Novotny EJ, Behar KL. Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions. Neurochem Res. 2003 Jun; 28(6):933-40. PMID: 12718448.
      View in: PubMed
    133. Farahani R, Haddad GG. Understanding the molecular responses to hypoxia using Drosophila as a genetic model. Respir Physiol Neurobiol. 2003 May 30; 135(2-3):221-9. PMID: 12809621.
      View in: PubMed
    134. Sun X, Gu XQ, Haddad GG. Calcium influx via L- and N-type calcium channels activates a transient large-conductance Ca2+-activated K+ current in mouse neocortical pyramidal neurons. J Neurosci. 2003 May 01; 23(9):3639-48. PMID: 12736335.
      View in: PubMed
    135. Gu XQ, Haddad GG. Maturation of neuronal excitability in hippocampal neurons of mice chronically exposed to cyclic hypoxia. Am J Physiol Cell Physiol. 2003 May; 284(5):C1156-63. PMID: 12676654.
      View in: PubMed
    136. Douglas RM, Haddad GG. Genetic models in applied physiology: invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest. J Appl Physiol (1985). 2003 May; 94(5):2068-83; discussion 2084. PMID: 12679355.
      View in: PubMed
    137. Douglas RM, Xue J, Chen JY, Haddad CG, Alper SL, Haddad GG. Chronic intermittent hypoxia decreases the expression of Na/H exchangers and HCO3-dependent transporters in mouse CNS. J Appl Physiol (1985). 2003 Jul; 95(1):292-9. PMID: 12665539.
      View in: PubMed
    138. Yao H, Gu XQ, Haddad GG. The role of HCO3(-)-dependent mechanisms in pHi regulation during O2 deprivation. Neuroscience. 2003; 117(1):29-35. PMID: 12605889.
      View in: PubMed
    139. Xue J, Douglas RM, Zhou D, Lim JY, Boron WF, Haddad GG. Expression of Na+/H+ and HCO3- -dependent transporters in Na+/H+ exchanger isoform 1 null mutant mouse brain. Neuroscience. 2003; 122(1):37-46. PMID: 14596847.
      View in: PubMed
    140. Lang K, Wagner C, Haddad G, Burnekova O, Geibel J. Intracellular pH activates membrane-bound Na(+)/H(+) exchanger and vacuolar H(+)-ATPase in human embryonic kidney (HEK) cells. Cell Physiol Biochem. 2003; 13(5):257-62. PMID: 14586169.
      View in: PubMed
    141. Xia Y, Zhao P, Xue J, Gu XQ, Sun X, Yao H, Haddad GG. Na+ channel expression and neuronal function in the Na+/H+ exchanger 1 null mutant mouse. J Neurophysiol. 2003 Jan; 89(1):229-36. PMID: 12522174.
      View in: PubMed
    142. Vicencio AG, Eickelberg O, Stankewich MC, Kashgarian M, Haddad GG. Regulation of TGF-beta ligand and receptor expression in neonatal rat lungs exposed to chronic hypoxia. J Appl Physiol (1985). 2002 Sep; 93(3):1123-30. PMID: 12183510.
      View in: PubMed
    143. Ma E, Tucker MC, Chen Q, Haddad GG. Developmental expression and enzymatic activity of pre-mRNA deaminase in Drosophila melanogaster. Brain Res Mol Brain Res. 2002 Jun 15; 102(1-2):100-4. PMID: 12191498.
      View in: PubMed
    144. Ma E, Haddad GG. Slot-blot hybridization in studying gene expression during oxygen deprivation. Methods Mol Biol. 2002; 196:139-45. PMID: 12152192.
      View in: PubMed
    145. Gibney GT, Zhang JH, Douglas RM, Haddad GG, Xia Y. Na(+)/Ca(2+) exchanger expression in the developing rat cortex. Neuroscience. 2002; 112(1):65-73. PMID: 12044472.
      View in: PubMed
    146. Haddad GG, Ma E. Neuronal tolerance to O2 deprivation in drosophila: novel approaches using genetic models. Neuroscientist. 2001 Dec; 7(6):538-50. PMID: 11765131.
      View in: PubMed
    147. Chen Q, Ma E, Behar KL, Xu T, Haddad GG. Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J Biol Chem. 2002 Feb 01; 277(5):3274-9. PMID: 11719513.
      View in: PubMed
    148. Yao H, Gu XQ, Douglas RM, Haddad GG. Role of Na(+)/H(+) exchanger during O(2) deprivation in mouse CA1 neurons. Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1205-10. PMID: 11546657.
      View in: PubMed
    149. Gu XQ, Haddad GG. Decreased neuronal excitability in hippocampal neurons of mice exposed to cyclic hypoxia. J Appl Physiol (1985). 2001 Sep; 91(3):1245-50. PMID: 11509522.
      View in: PubMed
    150. Gu XQ, Yao H, Haddad GG. Increased neuronal excitability and seizures in the Na(+)/H(+) exchanger null mutant mouse. Am J Physiol Cell Physiol. 2001 Aug; 281(2):C496-503. PMID: 11443048.
      View in: PubMed
    151. Xia Y, Haddad GG. Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain. J Comp Neurol. 2001 Jul 23; 436(2):202-10. PMID: 11438924.
      View in: PubMed
    152. Douglas RM, Xu T, Haddad GG. Cell cycle progression and cell division are sensitive to hypoxia in Drosophila melanogaster embryos. Am J Physiol Regul Integr Comp Physiol. 2001 May; 280(5):R1555-63. PMID: 11294781.
      View in: PubMed
    153. Ma E, Gu XQ, Wu X, Xu T, Haddad GG. Mutation in pre-mRNA adenosine deaminase markedly attenuates neuronal tolerance to O2 deprivation in Drosophila melanogaster. J Clin Invest. 2001 Mar; 107(6):685-93. PMID: 11254668.
      View in: PubMed
    154. Novotny EJ, Ariyan C, Mason GF, O'Reilly J, Haddad GG, Behar KL. Differential increase in cerebral cortical glucose oxidative metabolism during rat postnatal development is greater in vivo than in vitro. Brain Res. 2001 Jan 12; 888(2):193-202. PMID: 11150475.
      View in: PubMed
    155. Douglas RM, Schmitt BM, Xia Y, Bevensee MO, Biemesderfer D, Boron WF, Haddad GG. Sodium-hydrogen exchangers and sodium-bicarbonate co-transporters: ontogeny of protein expression in the rat brain. Neuroscience. 2001; 102(1):217-28. PMID: 11226686.
      View in: PubMed
    156. Zhang J, Haddad GG, Xia Y. delta-, but not mu- and kappa-, opioid receptor activation protects neocortical neurons from glutamate-induced excitotoxic injury. Brain Res. 2000 Dec 08; 885(2):143-53. PMID: 11102568.
      View in: PubMed
    157. Gu XQ, Yao H, Haddad GG. Effect of extracellular HCO(3)(-) on Na(+) channel characteristics in hippocampal CA1 neurons. J Neurophysiol. 2000 Nov; 84(5):2477-83. PMID: 11067990.
      View in: PubMed
    158. Banasiak KJ, Xia Y, Haddad GG. Mechanisms underlying hypoxia-induced neuronal apoptosis. Prog Neurobiol. 2000 Oct; 62(3):215-49. PMID: 10840148.
      View in: PubMed
    159. Schmitt BM, Berger UV, Douglas RM, Bevensee MO, Hediger MA, Haddad GG, Boron WF. Na/HCO3 cotransporters in rat brain: expression in glia, neurons, and choroid plexus. J Neurosci. 2000 Sep 15; 20(18):6839-48. PMID: 10995828.
      View in: PubMed
    160. Haddad GG. Enhancing our understanding of the molecular responses to hypoxia in mammals using Drosophila melanogaster. J Appl Physiol (1985). 2000 Apr; 88(4):1481-7. PMID: 10749845.
      View in: PubMed
    161. Xia Y, Fung ML, O'Reilly JP, Haddad GG. Increased neuronal excitability after long-term O(2) deprivation is mediated mainly by sodium channels. Brain Res Mol Brain Res. 2000 Mar 29; 76(2):211-9. PMID: 10762696.
      View in: PubMed
    162. Haddad GG, Liu H. Different O2-sensing mechanisms by different K+ channels. Adv Exp Med Biol. 2000; 475:441-52. PMID: 10849685.
      View in: PubMed
    163. Ma E, Haddad GG. Isolation and characterization of the hypoxia-inducible factor 1beta in Drosophila melanogaster. Brain Res Mol Brain Res. 1999 Nov 10; 73(1-2):11-6. PMID: 10581393.
      View in: PubMed
    164. Fung ML, Croning MD, Haddad GG. Sodium homeostasis in rat hippocampal slices during oxygen and glucose deprivation: role of voltage-sensitive sodium channels. Neurosci Lett. 1999 Nov 05; 275(1):41-4. PMID: 10554980.
      View in: PubMed
    165. Haddad GG. Use of genetic models in respiratory neurobiology and sleep. Curr Opin Pulm Med. 1999 Nov; 5(6):349-54. PMID: 10570735.
      View in: PubMed
    166. Gu XQ, Haddad GG. Drosophila neurons respond differently to hypoxia and cyanide than rat neurons. Brain Res. 1999 Oct 16; 845(1):6-13. PMID: 10529438.
      View in: PubMed
    167. Banasiak KJ, Cronin T, Haddad GG. bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis. Brain Res Mol Brain Res. 1999 Oct 01; 72(2):214-25. PMID: 10529480.
      View in: PubMed
    168. Yao H, Ma E, Gu XQ, Haddad GG. Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice. J Clin Invest. 1999 Sep; 104(5):637-45. PMID: 10487778.
      View in: PubMed
    169. Liu H, Moczydlowski E, Haddad GG. O(2) deprivation inhibits Ca(2+)-activated K(+) channels via cytosolic factors in mice neocortical neurons. J Clin Invest. 1999 Sep; 104(5):577-88. PMID: 10487772.
      View in: PubMed
    170. Ma E, Haddad G. A Drosophila CDK5alpha-like molecule and its possible role in response to O(2) deprivation. Biochem Biophys Res Commun. 1999 Aug 02; 261(2):459-63. PMID: 10425207.
      View in: PubMed
    171. Ma E, Xu T, Haddad GG. Gene regulation by O2 deprivation: an anoxia-regulated novel gene in Drosophila melanogaster. Brain Res Mol Brain Res. 1999 Jan 08; 63(2):217-24. PMID: 9878744.
      View in: PubMed
    172. Xia Y, Haddad GG. Effect of prolonged O2 deprivation on Na+ channels: differential regulation in adult versus fetal rat brain. Neuroscience. 1999; 94(4):1231-43. PMID: 10625063.
      View in: PubMed
    173. McKeage MJ, Haddad GG, Ding L, Galettis P, Screnci D, Zhuang L, Baguley BC. Neuroprotective interactions in rats between paclitaxel and cisplatin. Oncol Res. 1999; 11(6):287-93. PMID: 10691031.
      View in: PubMed
    174. Banasiak KJ, Haddad GG. Hypoxia-induced apoptosis: effect of hypoxic severity and role of p53 in neuronal cell death. Brain Res. 1998 Jun 29; 797(2):295-304. PMID: 9666152.
      View in: PubMed
    175. Croning MD, Haddad GG. Comparison of brain slice chamber designs for investigations of oxygen deprivation in vitro. J Neurosci Methods. 1998 Jun 01; 81(1-2):103-11. PMID: 9696315.
      View in: PubMed
    176. Chow E, Haddad GG. Differential effects of anoxia and glutamate on cultured neocortical neurons. Exp Neurol. 1998 Mar; 150(1):52-9. PMID: 9514836.
      View in: PubMed
    177. Friedman JE, Chow EJ, Haddad GG. State of actin filaments is changed by anoxia in cultured rat neocortical neurons. Neuroscience. 1998 Jan; 82(2):421-7. PMID: 9466451.
      View in: PubMed
    178. Haddad GG. Mechanisms of anoxia tolerance. A novel approach using a Drosophila model system. Adv Exp Med Biol. 1998; 454:273-80. PMID: 9889901.
      View in: PubMed
    179. Xia Y, Warshaw JB, Haddad GG. Effect of chronic hypoxia on glucose transporters in heart and skeletal muscle of immature and adult rats. Am J Physiol. 1997 11; 273(5):R1734-41. PMID: 9374817.
      View in: PubMed
    180. Haddad GG, Sun Ya, Wyman RJ, Xu T. Genetic basis of tolerance to O2 deprivation in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1997 Sep 30; 94(20):10809-12. PMID: 9380715.
      View in: PubMed
    181. O'Reilly JP, Cummins TR, Haddad GG. Oxygen deprivation inhibits Na+ current in rat hippocampal neurones via protein kinase C. J Physiol. 1997 Sep 15; 503 ( Pt 3):479-88. PMID: 9379405.
      View in: PubMed
    182. Chan HS, Grogan TM, Haddad G, Hipfner DR, Deeley RG, Cole SP. Standardization of a single-cell assay for sensitive detection of multidrug resistance protein expression in normal and malignant cells in archival clinical samples. J Lab Clin Med. 1997 Sep; 130(3):297-306. PMID: 9341990.
      View in: PubMed
    183. Chidekel AS, Friedman JE, Haddad GG. Anoxia-induced neuronal injury: role of Na+ entry and Na+-dependent transport. Exp Neurol. 1997 Aug; 146(2):403-13. PMID: 9270051.
      View in: PubMed
    184. Fung ML, Haddad GG. Anoxia-induced depolarization in CA1 hippocampal neurons: role of Na+-dependent mechanisms. Brain Res. 1997 Jul 11; 762(1-2):97-102. PMID: 9262163.
      View in: PubMed
    185. Bkaily G, Pothier P, D'Orléans-Juste P, Simaan M, Jacques D, Jaalouk D, Belzile F, Hassan G, Boutin C, Haddad G, Neugebauer W. The use of confocal microscopy in the investigation of cell structure and function in the heart, vascular endothelium and smooth muscle cells. Mol Cell Biochem. 1997 Jul; 172(1-2):171-94. PMID: 9278244.
      View in: PubMed
    186. Ma E, Haddad GG. Expression and localization of Na+/H+ exchangers in rat central nervous system. Neuroscience. 1997 Jul; 79(2):591-603. PMID: 9200742.
      View in: PubMed
    187. Chan HS, Lu Y, Grogan TM, Haddad G, Hipfner DR, Cole SP, Deeley RG, Ling V, Gallie BL. Multidrug resistance protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein. Cancer Res. 1997 Jun 15; 57(12):2325-30. PMID: 9192801.
      View in: PubMed
    188. Ma E, Haddad GG. Anoxia regulates gene expression in the central nervous system of Drosophila melanogaster. Brain Res Mol Brain Res. 1997 Jun; 46(1-2):325-8. PMID: 9191110.
      View in: PubMed
    189. HADDAD GG, WYMAN RJ, MOHSENIN A, SUN Y, KRISHNAN SN. Behavioral and Electrophysiologic Responses of Drosophila melanogaster to Prolonged Periods of Anoxia. J Insect Physiol. 1997 Mar; 43(3):203-210. PMID: 12769903.
      View in: PubMed
    190. Haddad GG. K+ ions and channels: mechanisms of sensing O2 deprivation in central neurons. Kidney Int. 1997 Feb; 51(2):467-72. PMID: 9027723.
      View in: PubMed
    191. Jiang C, Haddad GG. Modulation of K+ channels by intracellular ATP in human neocortical neurons. J Neurophysiol. 1997 Jan; 77(1):93-102. PMID: 9120601.
      View in: PubMed
    192. Marks JD, Friedman JE, Haddad GG. Vulnerability of CA1 neurons to glutamate is developmentally regulated. Brain Res Dev Brain Res. 1996 Dec 23; 97(2):194-206. PMID: 8997504.
      View in: PubMed
    193. Bevensee MO, Cummins TR, Haddad GG, Boron WF, Boyarsky G. pH regulation in single CA1 neurons acutely isolated from the hippocampi of immature and mature rats. J Physiol. 1996 Jul 15; 494 ( Pt 2):315-28. PMID: 8841993.
      View in: PubMed
    194. O'Reilly JP, Haddad GG. Chronic hypoxia in vivo renders neocortical neurons more vulnerable to subsequent acute hypoxic stress. Brain Res. 1996 Mar 04; 711(1-2):203-10. PMID: 8680864.
      View in: PubMed
    195. Bkaily G, Haddad G, Jaalouk D, Gros-Louis N, Benchekroun MT, Naik R, Pothier P, D'Orléans-Juste P, Bui M, Wang S, Sperelakis N. Modulation of Ca2+ and Na+ transport by taurine in heart and vascular smooth muscle. Adv Exp Med Biol. 1996; 403:263-73. PMID: 8915363.
      View in: PubMed
    196. Krishnan SN, Desai T, Ward DC, Haddad GG. Isolation and chromosomal localization of a human ATP-regulated potassium channel. Hum Genet. 1995 Aug; 96(2):155-60. PMID: 7635463.
      View in: PubMed
    197. O'Reilly JP, Jiang C, Haddad GG. Major differences in response to graded hypoxia between hypoglossal and neocortical neurons. Brain Res. 1995 Jun 19; 683(2):179-86. PMID: 7552353.
      View in: PubMed
    198. Xia Y, Warshaw JB, Haddad GG. Chronic hypoxia causes opposite effects on glucose transporter 1 mRNA in mature versus immature rat brain. Brain Res. 1995 Mar 27; 675(1-2):224-30. PMID: 7796133.
      View in: PubMed
    199. Jiang C, Haddad GG. Oxygen deprivation inhibits a K+ channel independently of cytosolic factors in rat central neurons. J Physiol. 1994 Nov 15; 481 ( Pt 1):15-26. PMID: 7853238.
      View in: PubMed
    200. Friedman JE, Haddad GG. Anoxia induces an increase in intracellular sodium in rat central neurons in vitro. Brain Res. 1994 Nov 14; 663(2):329-34. PMID: 7874519.
      View in: PubMed
    201. Jiang C, Sigworth FJ, Haddad GG. Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons. J Neurosci. 1994 Sep; 14(9):5590-602. PMID: 8083755.
      View in: PubMed
    202. Jiang C, Haddad GG. A direct mechanism for sensing low oxygen levels by central neurons. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7198-201. PMID: 8041769.
      View in: PubMed
    203. Xia Y, Haddad GG. Postnatal development of voltage-sensitive Na+ channels in rat brain. J Comp Neurol. 1994 Jul 08; 345(2):279-87. PMID: 7929902.
      View in: PubMed
    204. Friedman JE, Haddad GG. Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons. Brain Res. 1994 Mar 28; 641(1):57-64. PMID: 8019852.
      View in: PubMed
    205. Cummins TR, Xia Y, Haddad GG. Functional properties of rat and human neocortical voltage-sensitive sodium currents. J Neurophysiol. 1994 Mar; 71(3):1052-64. PMID: 8201401.
      View in: PubMed
    206. Xia Y, Haddad GG. Voltage-sensitive Na+ channels increase in number in newborn rat brain after in utero hypoxia. Brain Res. 1994 Jan 28; 635(1-2):339-44. PMID: 8173974.
      View in: PubMed
    207. Haddad GG, Jiang C. Mechanisms of neuronal survival during hypoxia: ATP-sensitive K+ channels. Biol Neonate. 1994; 65(3-4):160-5. PMID: 8038277.
      View in: PubMed
    208. Jiang C, Cummins TR, Haddad GG. Membrane ionic currents and properties of freshly dissociated rat brainstem neurons. Exp Brain Res. 1994; 100(3):407-20. PMID: 7813679.
      View in: PubMed
    209. D'Andrea LA, Rosen CL, Haddad GG. Severe hypoxemia in children with upper airway obstruction during sleep does not lead to significant changes in heart rate. Pediatr Pulmonol. 1993 Dec; 16(6):362-9. PMID: 8134159.
      View in: PubMed
    210. Xia Y, Eisenman D, Haddad GG. Sulfonylurea receptor expression in rat brain: effect of chronic hypoxia during development. Pediatr Res. 1993 Nov; 34(5):634-41. PMID: 8284102.
      View in: PubMed
    211. Haddad GG, Jiang C. Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat. Brain Res. 1993 Oct 22; 625(2):261-8. PMID: 7903900.
      View in: PubMed
    212. Kwei S, Jiang C, Haddad GG. Acute anoxia-induced alterations in MAP2 immunoreactivity and neuronal morphology in rat hippocampus. Brain Res. 1993 Aug 27; 620(2):203-10. PMID: 8369956.
      View in: PubMed
    213. Jiang C, Haddad GG. Short periods of hypoxia activate a K+ current in central neurons. Brain Res. 1993 Jun 18; 614(1-2):352-6. PMID: 8348327.
      View in: PubMed
    214. Xia Y, Haddad GG. Neuroanatomical distribution and binding properties of saxitoxin sites in the rat and turtle CNS. J Comp Neurol. 1993 Apr 15; 330(3):363-80. PMID: 8468412.
      View in: PubMed
    215. Young RS, During MJ, Donnelly DF, Aquila WJ, Perry VL, Haddad GG. Effect of anoxia on excitatory amino acids in brain slices of rats and turtles: in vitro microdialysis. Am J Physiol. 1993 Apr; 264(4 Pt 2):R716-9. PMID: 8097385.
      View in: PubMed
    216. Haddad GG, Jiang C. O2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog Neurobiol. 1993 Mar; 40(3):277-318. PMID: 7680137.
      View in: PubMed
    217. Cummins TR, Agulian SK, Haddad GG. Oxygen tension clamp around single neurons in vitro: a computerized method for studies on O2 deprivation. J Neurosci Methods. 1993 Mar; 46(3):183-9. PMID: 8483311.
      View in: PubMed
    218. Rosen CL, Schecter WS, Mellins RB, Haddad GG. Effect of acute hypoxia on metabolism and ventilation in awake piglets. Respir Physiol. 1993 Mar; 91(2-3):307-19. PMID: 8469853.
      View in: PubMed
    219. Cummins TR, Jiang C, Haddad GG. Human neocortical excitability is decreased during anoxia via sodium channel modulation. J Clin Invest. 1993 Feb; 91(2):608-15. PMID: 8381823.
      View in: PubMed
    220. Friedman JE, Haddad GG. Major differences in Ca2+i response to anoxia between neonatal and adult rat CA1 neurons: role of Ca2+o and Na+o. J Neurosci. 1993 Jan; 13(1):63-72. PMID: 8093716.
      View in: PubMed
    221. Jiang C, Haddad GG. Differential responses of neocortical neurons to glucose and/or O2 deprivation in the human and rat. J Neurophysiol. 1992 Dec; 68(6):2165-73. PMID: 1491265.
      View in: PubMed
    222. Rosen CL, D'Andrea L, Haddad GG. Adult criteria for obstructive sleep apnea do not identify children with serious obstruction. Am Rev Respir Dis. 1992 Nov; 146(5 Pt 1):1231-4. PMID: 1443876.
      View in: PubMed
    223. Sanocka UM, Donnelly DF, Haddad GG. Autoresuscitation: a survival mechanism in piglets. J Appl Physiol (1985). 1992 Aug; 73(2):749-53. PMID: 1400005.
      View in: PubMed
    224. Xia Y, Haddad GG. Ontogeny and distribution of GABAA receptors in rat brainstem and rostral brain regions. Neuroscience. 1992 Aug; 49(4):973-89. PMID: 1331860.
      View in: PubMed
    225. Donnelly DF, Jiang C, Haddad GG. Comparative responses of brain stem and hippocampal neurons to O2 deprivation: in vitro intracellular studies. Am J Physiol. 1992 May; 262(5 Pt 1):L549-54. PMID: 1590406.
      View in: PubMed
    226. Xia Y, Jiang C, Haddad GG. Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. Am J Physiol. 1992 Apr; 262(4 Pt 2):R595-603. PMID: 1314516.
      View in: PubMed
    227. Jiang C, Xia Y, Haddad GG. Role of ATP-sensitive K+ channels during anoxia: major differences between rat (newborn and adult) and turtle neurons. J Physiol. 1992 Mar; 448:599-612. PMID: 1593480.
      View in: PubMed
    228. Jiang C, Agulian S, Haddad GG. Cl- and Na+ homeostasis during anoxia in rat hypoglossal neurons: intracellular and extracellular in vitro studies. J Physiol. 1992 Mar; 448:697-708. PMID: 1593484.
      View in: PubMed
    229. Jiang C, Agulian S, Haddad GG. O2 tension in adult and neonatal brain slices under several experimental conditions. Brain Res. 1991 Dec 24; 568(1-2):159-64. PMID: 1814564.
      View in: PubMed
    230. Xia Y, Haddad GG. Major differences in CNS sulfonylurea receptor distribution between the rat (newborn, adult) and turtle. J Comp Neurol. 1991 Dec 08; 314(2):278-89. PMID: 1787178.
      View in: PubMed
    231. Cummins TR, Donnelly DF, Haddad GG. Effect of metabolic inhibition on the excitability of isolated hippocampal CA1 neurons: developmental aspects. J Neurophysiol. 1991 Nov; 66(5):1471-82. PMID: 1662712.
      View in: PubMed
    232. Chan HS, Thorner PS, Haddad G, Gallie BL. Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression. Ophthalmology. 1991 Sep; 98(9):1425-31. PMID: 1682862.
      View in: PubMed
    233. Feldman JD, Bazzy AR, Cummins TR, Haddad GG. Developmental changes in neuromuscular transmission in the rat diaphragm. J Appl Physiol (1985). 1991 Jul; 71(1):280-6. PMID: 1655690.
      View in: PubMed
    234. Jiang C, Haddad GG. Effect of anoxia on intracellular and extracellular potassium activity in hypoglossal neurons in vitro. J Neurophysiol. 1991 Jul; 66(1):103-11. PMID: 1919660.
      View in: PubMed
    235. Xia Y, Haddad GG. Ontogeny and distribution of opioid receptors in the rat brainstem. Brain Res. 1991 May 24; 549(2):181-93. PMID: 1653081.
      View in: PubMed
    236. Haddad GG, Donnelly DF. O2 deprivation induces a major depolarization in brain stem neurons in the adult but not in the neonatal rat. J Physiol. 1990 Oct; 429:411-28. PMID: 2126043.
      View in: PubMed
    237. Haddad GG, Donnelly DF, Getting PA. Biophysical properties of hypoglossal neurons in vitro: intracellular studies in adult and neonatal rats. J Appl Physiol (1985). 1990 Oct; 69(4):1509-17. PMID: 2262474.
      View in: PubMed
    238. Dekin MS, Haddad GG. Membrane and cellular properties in oscillating networks: implications for respiration. J Appl Physiol (1985). 1990 Sep; 69(3):809-21. PMID: 2246168.
      View in: PubMed
    239. Cote A, Haddad GG. Effect of sleep on regional blood flow distribution in piglets. Pediatr Res. 1990 Sep; 28(3):218-22. PMID: 2235117.
      View in: PubMed
    240. Donnelly DF, Haddad GG. Prolonged apnea and impaired survival in piglets after sinus and aortic nerve section. J Appl Physiol (1985). 1990 Mar; 68(3):1048-52. PMID: 2341332.
      View in: PubMed
    241. Haddad GG, Getting PA. Repetitive firing properties of neurons in the ventral region of nucleus tractus solitarius. In vitro studies in adult and neonatal rat. J Neurophysiol. 1989 Dec; 62(6):1213-24. PMID: 2600620.
      View in: PubMed
    242. Singh M, Rosen CL, Chang KJ, Haddad GG. Plasma beta-casomorphin-7 immunoreactive peptide increases after milk intake in newborn but not in adult dogs. Pediatr Res. 1989 Jul; 26(1):34-8. PMID: 2771507.
      View in: PubMed
    243. Rosen CL, Cote A, Haddad GG. Effect of enkephalins on cardiac output and regional blood flow in conscious dogs. Am J Physiol. 1989 Jun; 256(6 Pt 2):H1651-8. PMID: 2500032.
      View in: PubMed
    244. Bazzy AR, Pang LM, Akabas SR, Haddad GG. O2 metabolism of the sheep diaphragm during flow resistive loaded breathing. J Appl Physiol (1985). 1989 May; 66(5):2305-11. PMID: 2745294.
      View in: PubMed
    245. Akabas SR, Bazzy AR, DiMauro S, Haddad GG. Metabolic and functional adaptation of the diaphragm to training with resistive loads. J Appl Physiol (1985). 1989 Feb; 66(2):529-35. PMID: 2540138.
      View in: PubMed
    246. Schaeffer JI, Haddad GG. Ventilatory response to moderate and severe hypoxia in adult dogs: role of endorphins. J Appl Physiol (1985). 1988 Sep; 65(3):1383-8. PMID: 3141354.
      View in: PubMed
    247. Bazzy AR, Akabas SR, Hays AP, Haddad GG. Respiratory muscle response to load and glycogen content in type I and II fibers. Exp Neurol. 1988 Jul; 101(1):17-28. PMID: 3391257.
      View in: PubMed
    248. Sanocka UM, Donnelly DF, Haddad GG. Cardiovascular and neurophysiologic changes during graded duration of apnea in piglets. Pediatr Res. 1988 Apr; 23(4):402-7. PMID: 3374994.
      View in: PubMed
    249. Haddad GG, Jeng HJ, Lai TL. Heart rate variability during respiratory pauses in puppies and dogs. Pediatr Res. 1987 Sep; 22(3):306-11. PMID: 3658551.
      View in: PubMed
    250. Haddad GG, Jeng HJ, Lai TL, Mellins RB. Determination of sleep state in infants using respiratory variability. Pediatr Res. 1987 Jun; 21(6):556-62. PMID: 3601474.
      View in: PubMed
    251. Haddad GG, Jeng HJ, Bazzy AR, Lai TL. Within-breath electromyographic changes during loaded breathing in adult sheep. J Appl Physiol (1985). 1986 Oct; 61(4):1316-21. PMID: 3781946.
      View in: PubMed
    252. Bazzy AR, Korten JB, Haddad GG. Increase in electromyogram low-frequency power in nonfatigued contracting skeletal muscle. J Appl Physiol (1985). 1986 Sep; 61(3):1012-7. PMID: 3759739.
      View in: PubMed
    253. Donnelly DF, Haddad GG. Respiratory changes induced by prolonged laryngeal stimulation in awake piglets. J Appl Physiol (1985). 1986 Sep; 61(3):1018-24. PMID: 3759740.
      View in: PubMed
    254. Schaeffer JI, Haddad GG. Regulation of ventilation and oxygen consumption by delta- and mu-opioid receptor agonists. J Appl Physiol (1985). 1985 Sep; 59(3):959-68. PMID: 2997105.
      View in: PubMed
    255. Sadoul N, Bazzy AR, Akabas SR, Haddad GG. Ventilatory response to fatiguing and nonfatiguing resistive loads in awake sheep. J Appl Physiol (1985). 1985 Sep; 59(3):969-78. PMID: 4055582.
      View in: PubMed
    256. Haddad GG, Schaeffer JI, Chang KJ. Opposite effects of the delta- and mu-opioid receptor agonists on ventilation in conscious adult dogs. Brain Res. 1984 Dec 03; 323(1):73-82. PMID: 6098337.
      View in: PubMed
    257. Mellins RB, Haddad GG. Cardiorespiratory control in sudden infant death syndrome. Prog Clin Biol Res. 1983; 136:51-7. PMID: 6420807.
      View in: PubMed
    258. Mellins RB, Haddad GG. Respiratory control in early life: an overview. Prog Clin Biol Res. 1983; 136:3-15. PMID: 6364172.
      View in: PubMed
    259. Haddad GG, Gandhi MR, Mellins RB. Maturation of ventilatory response to hypoxia in puppies during sleep. J Appl Physiol Respir Environ Exerc Physiol. 1982 Feb; 52(2):309-14. PMID: 7061286.
      View in: PubMed
    260. Haddad GG, Walsh EM, Leistner HL, Grodin WK, Mellins RB. Abnormal maturation of sleep states in infants with aborted sudden infant death syndrome. Pediatr Res. 1981 Jul; 15(7):1055-7. PMID: 7254951.
      View in: PubMed
    261. Haddad GG, Leistner HL, Lai TL, Mellins RB. Ventilation and ventilatory pattern during sleep in aborted sudden infant death syndrome. Pediatr Res. 1981 May; 15(5):879-83. PMID: 6787545.
      View in: PubMed
    262. Haddad GG, Epstein RA, Epstein MA, Leistner HL, Mellins RB. The R-R interval and R-R variability in normal infants during sleep. Pediatr Res. 1980 Jun; 14(6):809-11. PMID: 7402755.
      View in: PubMed
    263. Haddad GG, Leistner HL, Epstein RA, Epstein MA, Grodin WK, Mellins RB. CO2-induced changes in ventilation and ventilatory pattern in normal sleeping infants. J Appl Physiol Respir Environ Exerc Physiol. 1980 Apr; 48(4):684-8. PMID: 6769883.
      View in: PubMed
    264. Mazza NM, Epstein MA, Haddad GG, Law HS, Mellins RB, Epstein RA. Relation of beat-to-beat variability to heart rate in normal sleeping infants. Pediatr Res. 1980 Mar; 14(3):232-5. PMID: 7383743.
      View in: PubMed
    265. Haddad GG, Krongrad E, Epstein RA, Epstein MA, Law HS, Katz JB, Mazza NM, Mellins RB. Effect of sleep state on the QT interval in normal infants. Pediatr Res. 1979 Feb; 13(2):139-41. PMID: 219413.
      View in: PubMed
    266. Haddad GG, Epstein MA, Epstein RA, Mazza NM, Mellins RB, Krongrad E. The QT interval in aborted sudden infant death syndrome infants. Pediatr Res. 1979 Feb; 13(2):136-8. PMID: 219412.
      View in: PubMed
    267. Haddad GG, Mellins RB. The role of airway receptors in the control of respiration in infants: a review. J Pediatr. 1977 Aug; 91(2):281-6. PMID: 874688.
      View in: PubMed
    268. Armstrong RW, Arkayin B, Haddad G. Fracture of bone materials in compression at temperatures between -200 degree C and +200 degree C. Nature. 1971 Aug 20; 232(5312):576-7. PMID: 4937508.
      View in: PubMed