Christopher Benner

Title(s)Associate Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Diego, La JollaPhD01/2009Bioinformatics
    University of California, San Diego , La JollaBS06/2002Bioengineering

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Decoding the grammar of transcriptional enhancers regulating different stages of opioid use disorder
    NIH U01DA051972Sep 30, 2020 - Jul 31, 2025
    Role: Co-Principal Investigator
    Uncovering how transcription and chromatin 3D structure impact one another during cellular activation
    NIH R01GM134366Sep 16, 2019 - Jun 30, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Nat Commun. 2022 06 25; 13(1):3646. Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, Cortés-Medina LV, Moresco JJ, Dunn S, Hernandez-Benitez R, Hishida T, Kim NY, Andijani MM, Bi C, Ku M, Takahashi Y, Xu J, Qiu J, Huang L, Benner C, Aizawa E, Qu J, Liu GH, Li Z, Yi F, Ghosheh Y, Shao C, Shokhirev M, Comoli P, Frassoni F, Yates JR, Fu XD, Esteban CR, Hamdan S, Li M, Izpisua Belmonte JC. PMID: 35752626; PMCID: PMC9233711.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction. Front Neurosci. 2022; 16:858427. Duttke SH, Montilla-Perez P, Chang MW, Li H, Chen H, Carrette LLG, de Guglielmo G, George O, Palmer AA, Benner C, Telese F. PMID: 35651629; PMCID: PMC9149415.
      View in: PubMed   Mentions:
    3. Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection. Physiol Rev. 2022 07 01; 102(3):1449-1494. Fischer F, Grigolon G, Benner C, Ristow M. PMID: 35343830.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Decoding Transcription Regulatory Mechanisms Associated with Coccidioides immitis Phase Transition Using Total RNA. mSystems. 2022 Feb 22; 7(1):e0140421. Duttke SH, Beyhan S, Singh R, Neal S, Viriyakosol S, Fierer J, Kirkland TN, Stajich JE, Benner C, Carlin AF. PMID: 35076277; PMCID: PMC8788335.
      View in: PubMed   Mentions:
    5. Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy. Nat Microbiol. 2021 10; 6(10):1319-1333. Martin-Sancho L, Tripathi S, Rodriguez-Frandsen A, Pache L, Sanchez-Aparicio M, McGregor MJ, Haas KM, Swaney DL, Nguyen TT, Mamede JI, Churas C, Pratt D, Rosenthal SB, Riva L, Nguyen C, Beltran-Raygoza N, Soonthornvacharin S, Wang G, Jimenez-Morales D, De Jesus PD, Moulton HM, Stein DA, Chang MW, Benner C, Ideker T, Albrecht RA, Hultquist JF, Krogan NJ, García-Sastre A, Chanda SK. PMID: 34556855.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19. bioRxiv. 2021 Aug 24. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 34462742; PMCID: PMC8404884.
      View in: PubMed   Mentions: 1  
    7. A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells. NAR Genom Bioinform. 2021 Sep; 3(3):lqab061. Shamie I, Duttke SH, Karottki KJC, Han CZ, Hansen AH, Hefzi H, Xiong K, Li S, Roth SJ, Tao J, Lee GM, Glass CK, Kildegaard HF, Benner C, Lewis NE. PMID: 34268494; PMCID: PMC8276764.
      View in: PubMed   Mentions: 2  
    8. DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells. J Exp Med. 2021 07 05; 218(7). Lim JY, Duttke SH, Baker TS, Lee J, Gambino KJ, Venturini NJ, Ho JSY, Zheng S, Fstkchyan YS, Pillai V, Fajgenbaum DC, Marazzi I, Benner C, Byun M. PMID: 33970190; PMCID: PMC8111463.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Functional landscape of SARS-CoV-2 cellular restriction. Mol Cell. 2021 06 17; 81(12):2656-2668.e8. Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Curry HM, Oom AL, Miorin L, Rodriguez-Frandsen A, Zheng F, Wu C, Xiong Y, Urbanowski M, Shaw ML, Chang MW, Benner C, Hope TJ, Frieman MB, García-Sastre A, Ideker T, Hultquist JF, Guatelli J, Chanda SK. PMID: 33930332; PMCID: PMC8043580.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    10. TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Cell. 2021 05 13; 184(10):2618-2632.e17. Ho JSY, Mok BW, Campisi L, Jordan T, Yildiz S, Parameswaran S, Wayman JA, Gaudreault NN, Meekins DA, Indran SV, Morozov I, Trujillo JD, Fstkchyan YS, Rathnasinghe R, Zhu Z, Zheng S, Zhao N, White K, Ray-Jones H, Malysheva V, Thiecke MJ, Lau SY, Liu H, Zhang AJ, Lee AC, Liu WC, Jangra S, Escalera A, Aydillo T, Melo BS, Guccione E, Sebra R, Shum E, Bakker J, Kaufman DA, Moreira AL, Carossino M, Balasuriya UBR, Byun M, Albrecht RA, Schotsaert M, Garcia-Sastre A, Chanda SK, Miraldi ER, Jeyasekharan AD, TenOever BR, Spivakov M, Weirauch MT, Heinz S, Chen H, Benner C, Richt JA, Marazzi I. PMID: 33836156; PMCID: PMC8008343.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    11. Inner-nuclear-membrane-associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity. Mol Biol Cell. 2021 04 01; 32(7):521-537. Flagg MP, Wangeline MA, Holland SR, Duttke SH, Benner C, Neal S, Hampton RY. PMID: 33566711; PMCID: PMC8101470.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytes. JCI Insight. 2021 01 11; 6(1). Tu LN, Hsieh L, Kajimoto M, Charette K, Kibiryeva N, Forero A, Hampson S, Marshall JA, O'Brien J, Scatena M, Portman MA, Savan R, Benner C, Aliseda A, Nuri M, Bittel D, Pastuszko P, Nigam V. PMID: 33232305; PMCID: PMC7821587.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    13. Ncor2/PPARα-Dependent Upregulation of MCUb in the Type 2 Diabetic Heart Impacts Cardiac Metabolic Flexibility and Function. Diabetes. 2021 03; 70(3):665-679. Cividini F, Scott BT, Suarez J, Casteel DE, Heinz S, Dai A, Diemer T, Suarez JA, Benner CW, Ghassemian M, Dillmann WH. PMID: 33303689; PMCID: PMC7897348.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models. bioRxiv. 2020 Dec 01. Yuin Ho JS, Wing-Yee Mok B, Campisi L, Jordan T, Yildiz S, Parameswaran S, Wayman JA, Gaudreault NN, Meekins DA, Indran SV, Morozov I, Trujillo JD, Fstkchyan YS, Rathnasinghe R, Zhu Z, Zheng S, Zhao N, White K, Ray-Jones H, Malysheva V, Thiecke MJ, Lau SY, Liu H, Junxia Zhang A, Chak-Yiu Lee A, Liu WC, Aydillo T, Salom Melo B, Guccione E, Sebra R, Shum E, Bakker J, Kaufman DA, Moreira AL, Carossino M, Balasuriya UBR, Byun M, Miraldi ER, Albrecht RA, Schotsaert M, Garcia-Sastre A, Chanda SK, Jeyasekharan AD, TenOever BR, Spivakov M, Weirauch MT, Heinz S, Chen H, Benner C, Richt JA, Marazzi I. PMID: 33299999; PMCID: PMC7724667.
      View in: PubMed   Mentions:
    15. Functional Landscape of SARS-CoV-2 Cellular Restriction. bioRxiv. 2020 Sep 30. Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Pratt D, Churas C, Rosenthal SB, Liu S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Oom AL, Miorin L, Rodriguez-Frandsen A, Urbanowski M, Shaw ML, Chang MW, Benner C, Frieman MB, García-Sastre A, Ideker T, Hultquist JF, Guatelli J, Chanda SK. PMID: 33024967; PMCID: PMC7536870.
      View in: PubMed   Mentions:
    16. MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates. BMC Bioinformatics. 2020 Sep 16; 21(1):410. Delos Santos NP, Texari L, Benner C. PMID: 32938397; PMCID: PMC7493370.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs. Nat Microbiol. 2020 12; 5(12):1490-1503. Tran V, Ledwith MP, Thamamongood T, Higgins CA, Tripathi S, Chang MW, Benner C, García-Sastre A, Schwemmle M, Boon ACM, Diamond MS, Mehle A. PMID: 32839537; PMCID: PMC7677226.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. A Genome-Wide CRISPR-Cas9 Screen Reveals the Requirement of Host Cell Sulfation for Schmallenberg Virus Infection. J Virol. 2020 08 17; 94(17). Thamamongood T, Aebischer A, Wagner V, Chang MW, Elling R, Benner C, García-Sastre A, Kochs G, Beer M, Schwemmle M. PMID: 32522852; PMCID: PMC7431805.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    19. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature. 2020 10; 586(7827):113-119. Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. PMID: 32707573; PMCID: PMC7603405.
      View in: PubMed   Mentions: 301     Fields:    Translation:HumansCellsPHPublic Health
    20. MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function. Bioinformatics. 2020 07 01; 36(Suppl_1):i84-i92. Shen Z, Hoeksema MA, Ouyang Z, Benner C, Glass CK. PMID: 32657363; PMCID: PMC7355228.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    21. Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection. Cell. 2020 06 25; 181(7):1502-1517.e23. Ho JSY, Angel M, Ma Y, Sloan E, Wang G, Martinez-Romero C, Alenquer M, Roudko V, Chung L, Zheng S, Chang M, Fstkchyan Y, Clohisey S, Dinan AM, Gibbs J, Gifford R, Shen R, Gu Q, Irigoyen N, Campisi L, Huang C, Zhao N, Jones JD, van Knippenberg I, Zhu Z, Moshkina N, Meyer L, Noel J, Peralta Z, Rezelj V, Kaake R, Rosenberg B, Wang B, Wei J, Paessler S, Wise HM, Johnson J, Vannini A, Amorim MJ, Baillie JK, Miraldi ER, Benner C, Brierley I, Digard P, Luksza M, Firth AE, Krogan N, Greenbaum BD, MacLeod MK, van Bakel H, Garcìa-Sastre A, Yewdell JW, Hutchinson E, Marazzi I. PMID: 32559462; PMCID: PMC7323901.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    22. ARTDeco: automatic readthrough transcription detection. BMC Bioinformatics. 2020 May 26; 21(1):214. Roth SJ, Heinz S, Benner C. PMID: 32456667; PMCID: PMC7249449.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    23. LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. Nat Commun. 2020 04 29; 11(1):2082. Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M. PMID: 32350257; PMCID: PMC7190832.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    24. A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals. bioRxiv. 2020 Apr 17. Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Burgstaller-Muehlbacher S, Pache L, De Jesus PP, Hull MV, Chang M, Chan JF, Cao J, Poon VK, Herbert K, Nguyen TT, Pu Y, Nguyen C, Rubanov A, Martinez-Sobrido L, Liu WC, Miorin L, White KM, Johnson JR, Benner C, Sun R, Schultz PG, Su A, Garcia-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. PMID: 32511357; PMCID: PMC7263415.
      View in: PubMed   Mentions: 1  
    25. ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9311-9317. Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. PMID: 32277030; PMCID: PMC7196839.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    26. NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult. Cell Mol Gastroenterol Hepatol. 2020; 10(1):133-147. Mennillo E, Yang X, Paszek M, Auwerx J, Benner C, Chen S. PMID: 32044398; PMCID: PMC7229481.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    27. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Hepatol Commun. 2020 Apr; 4(4):606-626. Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, Brenner D, Kisseleva T. PMID: 32258954; PMCID: PMC7109347.
      View in: PubMed   Mentions: 6     Fields:    
    28. Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa Cells. J Virol. 2020 01 31; 94(4). Rodriguez-Frandsen A, Martin-Sancho L, Gounder AP, Chang MW, Liu WC, De Jesus PD, von Recum-Knepper J, Dutra MS, Huffmaster NJ, Chavarria M, Mena I, Riva L, Nguyen CB, Dobariya S, Herbert KM, Benner C, Albrecht RA, García-Sastre A, Chanda SK. PMID: 31776276; PMCID: PMC6997754.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    29. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. 2020 05; 158(6):1728-1744.e14. Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. PMID: 31982409; PMCID: PMC7252905.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    30. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. J Hepatol. 2020 05; 72(5):946-959. Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T. PMID: 31899206; PMCID: PMC7167339.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    31. Identification and dynamic quantification of regulatory elements using total RNA. Genome Res. 2019 11; 29(11):1836-1846. Duttke SH, Chang MW, Heinz S, Benner C. PMID: 31649059; PMCID: PMC6836739.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    32. Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers. Cell. 2019 10 03; 179(2):373-391.e27. Brigidi GS, Hayes MGB, Delos Santos NP, Hartzell AL, Texari L, Lin PA, Bartlett A, Ecker JR, Benner C, Heinz S, Bloodgood BL. PMID: 31585079; PMCID: PMC6800120.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    33. Paradoxical association of TET loss of function with genome-wide DNA hypomethylation. Proc Natl Acad Sci U S A. 2019 08 20; 116(34):16933-16942. López-Moyado IF, Tsagaratou A, Yuita H, Seo H, Delatte B, Heinz S, Benner C, Rao A. PMID: 31371502; PMCID: PMC6708373.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    34. ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance. J Lipid Res. 2019 08; 60(8):1379-1395. Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM. PMID: 31092690; PMCID: PMC6672034.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    35. Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway. Protein Cell. 2019 07; 10(7):485-495. Hishida T, Vazquez-Ferrer E, Hishida-Nozaki Y, Sancho-Martinez I, Takahashi Y, Hatanaka F, Wu J, Ocampo A, Reddy P, Wu MZ, Gerken L, Shaw RJ, Rodriguez Esteban C, Benner C, Nakagawa H, Guillen Garcia P, Nuñez Delicado E, Castells A, Campistol JM, Liu GH, Izpisua Belmonte JC. PMID: 31041783; PMCID: PMC6588654.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nat Commun. 2019 04 03; 10(1):1523. Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK. PMID: 30944313; PMCID: PMC6447622.
      View in: PubMed   Mentions: 2460     Fields:    
    37. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife. 2019 03 06; 8. Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M. PMID: 30838976; PMCID: PMC6424562.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    38. MHC class II proteins mediate cross-species entry of bat influenza viruses. Nature. 2019 03; 567(7746):109-112. Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S. PMID: 30787439.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    39. Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages. Nat Commun. 2019 01 24; 10(1):414. Fonseca GJ, Tao J, Westin EM, Duttke SH, Spann NJ, Strid T, Shen Z, Stender JD, Sakai M, Link VM, Benner C, Glass CK. PMID: 30679424; PMCID: PMC6345992.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    40. A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PLoS Negl Trop Dis. 2018 12; 12(12):e0007053. Carlin AF, Wen J, Vizcarra EA, McCauley M, Chaillon A, Akrami K, Kim C, Ngono AE, Lara-Marquez ML, Smith DM, Glass CK, Schooley RT, Benner C, Shresta S. PMID: 30596671; PMCID: PMC6329527.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    41. Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9172-E9181. Carlin AF, Vizcarra EA, Branche E, Viramontes KM, Suarez-Amaran L, Ley K, Heinz S, Benner C, Shresta S, Glass CK. PMID: 30206152; PMCID: PMC6166801.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    42. Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2018 09; 561(7721):E1. Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29973714; PMCID: PMC7871211.
      View in: PubMed   Mentions: 1     Fields:    
    43. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018 09 06; 174(6):1522-1536.e22. Heinz S, Texari L, Hayes MGB, Urbanowski M, Chang MW, Givarkes N, Rialdi A, White KM, Albrecht RA, Pache L, Marazzi I, García-Sastre A, Shaw ML, Benner C. PMID: 30146161; PMCID: PMC6130916.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    44. Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. Mol Cell. 2018 06 07; 70(5):842-853.e7. Zhu Q, Hoong N, Aslanian A, Hara T, Benner C, Heinz S, Miga KH, Ke E, Verma S, Soroczynski J, Yates JR, Hunter T, Verma IM. PMID: 29861157; PMCID: PMC6545586.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    45. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 03 01; 69(5):915. Neal S, Jaeger PA, Duttke SH, Benner C, Glass CK, Ideker T, Hampton RY. PMID: 29499140.
      View in: PubMed   Mentions: 8     Fields:    
    46. Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies. J Immunol. 2018 03 01; 200(5):1702-1717. Prohaska TA, Que X, Diehl CJ, Hendrikx S, Chang MW, Jepsen K, Glass CK, Benner C, Witztum JL. PMID: 29378911; PMCID: PMC5821571.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    47. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 01 18; 69(2):306-320.e4. Neal S, Jaeger PA, Duttke SH, Benner C, K Glass C, Ideker T, Hampton RY. PMID: 29351849; PMCID: PMC6049073.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    48. Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2017 12 21; 552(7685):430. Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29168501; PMCID: PMC8594569.
      View in: PubMed   Mentions: 2     Fields:    
    49. Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells. Genes Dev. 2017 11 15; 31(22):2222-2234. Franks TM, McCloskey A, Shokirev MN, Benner C, Rathore A, Hetzer MW. PMID: 29269482; PMCID: PMC5769767.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    50. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2017 11 16; 551(7680):340-345. Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29144460; PMCID: PMC5884449.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    51. Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers. Elife. 2017 10 02; 6. Kelso TWR, Porter DK, Amaral ML, Shokhirev MN, Benner C, Hargreaves DC. PMID: 28967863; PMCID: PMC5643100.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    52. Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling. Nat Commun. 2017 09 29; 8(1):754. Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK, Lauberth SM. PMID: 28963538; PMCID: PMC5622043.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    53. Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN. Nature. 2017 09 20; 549(7673):548-552. Arnoult N, Correia A, Ma J, Merlo A, Garcia-Gomez S, Maric M, Tognetti M, Benner CW, Boulton SJ, Saghatelian A, Karlseder J. PMID: 28959974; PMCID: PMC5624508.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    54. Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2017 04 15; 31(8):845. Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 28512238; PMCID: PMC5435895.
      View in: PubMed   Mentions:    Fields:    
    55. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017 Apr 03; 127(4):1254-1270. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, Zhang M, Sun M, Cong M, Karin D, Taura K, Benner C, Heinz S, Bera T, Brenner DA, Kisseleva T. PMID: 28287406; PMCID: PMC5373891.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    56. Nucleoporin-mediated regulation of cell identity genes. Genes Dev. 2016 Oct 15; 30(20):2253-2258. Ibarra A, Benner C, Tyagi S, Cool J, Hetzer MW. PMID: 27807035; PMCID: PMC5110992.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    57. Nascent RNA sequencing reveals distinct features in plant transcription. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):12316-12321. Hetzel J, Duttke SH, Benner C, Chory J. PMID: 27729530; PMCID: PMC5087027.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    58. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. 2016 08 11; 536(7615):205-9. Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, Denman L, Harshman L, Baker C, Raja A, Penewit K, Janke N, Tang WJ, Ventura M, Banci L, Antonacci F, Akey JM, Amemiya CT, Gage FH, Reymond A, Eichler EE. PMID: 27487209; PMCID: PMC4988886.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    59. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66. Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK, Oegema K. PMID: 27432897; PMCID: PMC4949453.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    60. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes Dev. 2016 05 15; 30(10):1155-71. Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW. PMID: 27198230; PMCID: PMC4888837.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    61. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science. 2016 May 27; 352(6289):aad7993. Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JSY, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, Merad M, Jin J, Weirauch M, Heinz S, Benner C, van Bakel H, Basler C, García-Sastre A, Bukreyev A, Marazzi I. PMID: 27127234; PMCID: PMC5193222.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    62. BRD4 is a novel therapeutic target for liver fibrosis. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):15713-8. Ding N, Hah N, Yu RT, Sherman MH, Benner C, Leblanc M, He M, Liddle C, Downes M, Evans RM. PMID: 26644586; PMCID: PMC4697417.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    63. Perspectives on Unidirectional versus Divergent Transcription. Mol Cell. 2015 Nov 05; 60(3):348-9. Duttke SH, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. PMID: 26545075; PMCID: PMC4643650.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    64. Primate-specific ORF0 contributes to retrotransposon-mediated diversity. Cell. 2015 Oct 22; 163(3):583-93. Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. PMID: 26496605.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    65. New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12776-81. Benner C, Isoda T, Murre C. PMID: 26417104; PMCID: PMC4611620.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    66. Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis. Cancer Res. 2015 Sep 15; 75(18):3912-24. Wu MZ, Chen SF, Nieh S, Benner C, Ger LP, Jan CI, Ma L, Chen CH, Hishida T, Chang HT, Lin YS, Montserrat N, Gascon P, Sancho-Martinez I, Izpisua Belmonte JC. PMID: 26294212.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    67. The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing. Genes Dev. 2015 Jun 15; 29(12):1224-38. Jacinto FV, Benner C, Hetzer MW. PMID: 26080816; PMCID: PMC4495395.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    68. An alternative pluripotent state confers interspecies chimaeric competency. Nature. 2015 May 21; 521(7552):316-21. Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC. PMID: 25945737; PMCID: PMC5278765.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    69. SMADs and YAP compete to control elongation of β-catenin:LEF-1-recruited RNAPII during hESC differentiation. Mol Cell. 2015 Jun 04; 58(5):780-93. Estarás C, Benner C, Jones KA. PMID: 25936800; PMCID: PMC5315497.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    70. The DAXX co-repressor is directly recruited to active regulatory elements genome-wide to regulate autophagy programs in a model of human prostate cancer. Oncoscience. 2015; 2(4):362-72. Puto LA, Benner C, Hunter T. PMID: 26097870; PMCID: PMC4468322.
      View in: PubMed   Mentions: 10  
    71. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 2015 Jul; 100(7):945-54. Kashyap MK, Kumar D, Villa R, La Clair JJ, Benner C, Sasik R, Jones H, Ghia EM, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. PMID: 25862704; PMCID: PMC4486229.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    72. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nat Immunol. 2015 May; 16(5):485-94. Miller MS, Rialdi A, Ho JS, Tilove M, Martinez-Gil L, Moshkina NP, Peralta Z, Noel J, Melegari C, Maestre AM, Mitsopoulos P, Madrenas J, Heinz S, Benner C, Young JA, Feagins AR, Basler CF, Fernandez-Sesma A, Becherel OJ, Lavin MF, van Bakel H, Marazzi I. PMID: 25822250; PMCID: PMC4406851.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    73. An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors. Genes Dev. 2015 Mar 15; 29(6):603-16. Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li HR, Fu XD, Rauscher FJ, Yang J. PMID: 25762439; PMCID: PMC4378193.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    74. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. Circulation. 2015 Apr 07; 131(14):1278-1290. Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI. PMID: 25739401; PMCID: PMC4443804.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    75. The selection and function of cell type-specific enhancers. Nat Rev Mol Cell Biol. 2015 Mar; 16(3):144-54. Heinz S, Romanoski CE, Benner C, Glass CK. PMID: 25650801; PMCID: PMC4517609.
      View in: PubMed   Mentions: 419     Fields:    Translation:HumansAnimalsCells
    76. Human promoters are intrinsically directional. Mol Cell. 2015 Feb 19; 57(4):674-684. Duttke SHC, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. PMID: 25639469; PMCID: PMC4336624.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    77. Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):E297-302. Hah N, Benner C, Chong LW, Yu RT, Downes M, Evans RM. PMID: 25564661; PMCID: PMC4311831.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    78. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 2014 Dec 18; 159(7):1524-37. Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R. PMID: 25483777; PMCID: PMC4272762.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    79. Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization. Nucleic Acids Res. 2014 Nov 10; 42(20):12570-84. Kaikkonen MU, Niskanen H, Romanoski CE, Kansanen E, Kivelä AM, Laitalainen J, Heinz S, Benner C, Glass CK, Ylä-Herttuala S. PMID: 25352550; PMCID: PMC4227755.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    80. Function of a Foxp3 cis-element in protecting regulatory T cell identity. Cell. 2014 Aug 14; 158(4):734-748. Li X, Liang Y, LeBlanc M, Benner C, Zheng Y. PMID: 25126782; PMCID: PMC4151505.
      View in: PubMed   Mentions: 122     Fields:    Translation:AnimalsCells
    81. The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression. BMC Genomics. 2014 Jul 22; 15:620. Benner C, van der Meulen T, Cacéres E, Tigyi K, Donaldson CJ, Huising MO. PMID: 25051960; PMCID: PMC4124169.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    82. Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun. 2014 Jul 07; 5:4330. Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, Del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Belmonte JCI. PMID: 24999918; PMCID: PMC4291073.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    83. Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. Cell Stem Cell. 2014 Jul 03; 15(1):31-6. Suzuki K, Yu C, Qu J, Li M, Yao X, Yuan T, Goebl A, Tang S, Ren R, Aizawa E, Zhang F, Xu X, Soligalla RD, Chen F, Kim J, Kim NY, Liao HK, Benner C, Esteban CR, Jin Y, Liu GH, Li Y, Izpisua Belmonte JC. PMID: 24996168; PMCID: PMC4144407.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    84. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21. Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. PMID: 24584051; PMCID: PMC4113004.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    85. Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes. Protein Cell. 2014 Jan; 5(1):59-68. Gu Y, Liu GH, Plongthongkum N, Benner C, Yi F, Qu J, Suzuki K, Yang J, Zhang W, Li M, Montserrat N, Crespo I, Del Sol A, Esteban CR, Zhang K, Izpisua Belmonte JC. PMID: 24474197; PMCID: PMC3938846.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    86. Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions. PLoS Genet. 2013 Nov; 9(11):e1003906. Benner C, Konovalov S, Mackintosh C, Hutt KR, Stunnenberg R, Garcia-Bassets I. PMID: 24244184; PMCID: PMC3820735.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    87. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 2013 Nov 28; 503(7477):525-529. Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. PMID: 24153179; PMCID: PMC4064720.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    88. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem. 2013 Dec 06; 288(49):35222-36. Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS. PMID: 24145027; PMCID: PMC3853272.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    89. Effect of natural genetic variation on enhancer selection and function. Nature. 2013 Nov 28; 503(7477):487-92. Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, Glass CK. PMID: 24121437; PMCID: PMC3994126.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    90. Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes. Protein Cell. 2013 Aug 27. Gu Y, Liu GH, Plongthongkum N, Benner C, Yi F, Qu J, Suzuki K, Yang J, Zhang W, Li M, Montserrat N, Crespo I, Del Sol A, Esteban CR, Zhang K, Belmonte JC. PMID: 23982742.
      View in: PubMed   Mentions: 1     Fields:    
    91. Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell. 2013 Aug 08; 51(3):310-25. Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, Chun HB, Tough DF, Prinjha RK, Benner C, Glass CK. PMID: 23932714; PMCID: PMC3779836.
      View in: PubMed   Mentions: 333     Fields:    Translation:AnimalsCells
    92. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5. Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. PMID: 23728303; PMCID: PMC3839578.
      View in: PubMed   Mentions: 300     Fields:    Translation:AnimalsCells
    93. Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1. Nucleic Acids Res. 2013 Jul; 41(13):6391-402. Pham TH, Minderjahn J, Schmidl C, Hoffmeister H, Schmidhofer S, Chen W, Längst G, Benner C, Rehli M. PMID: 23658224; PMCID: PMC3711439.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    94. Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21028-33. Mansson R, Welinder E, Åhsberg J, Lin YC, Benner C, Glass CK, Lucas JS, Sigvardsson M, Murre C. PMID: 23213261; PMCID: PMC3529039.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    95. Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol. 2012 Dec; 13(12):1196-204. Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C. PMID: 23064439; PMCID: PMC3501570.
      View in: PubMed   Mentions: 145     Fields:    Translation:AnimalsCells
    96. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9448-53. Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. PMID: 22566629; PMCID: PMC3386114.
      View in: PubMed   Mentions: 313     Fields:    Translation:AnimalsCells
    97. Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states. Blood. 2012 Jun 14; 119(24):e161-71. Pham TH, Benner C, Lichtinger M, Schwarzfischer L, Hu Y, Andreesen R, Chen W, Rehli M. PMID: 22550342.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    98. Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 2011 Dec; 7(12):e1002401. Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. PMID: 22174696; PMCID: PMC3234212.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    99. Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity. 2011 Sep 23; 35(3):413-25. Mercer EM, Lin YC, Benner C, Jhunjhunwala S, Dutkowski J, Flores M, Sigvardsson M, Ideker T, Glass CK, Murre C. PMID: 21903424; PMCID: PMC3183365.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    100. Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011 May 15; 474(7351):390-4. Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. PMID: 21572438; PMCID: PMC3117022.
      View in: PubMed   Mentions: 482     Fields:    Translation:HumansCells
    101. Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol. 2011 Feb; 31(4):861-75. Sullivan AL, Benner C, Heinz S, Huang W, Xie L, Miano JM, Glass CK. PMID: 21135125; PMCID: PMC3028656.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    102. Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes Dev. 2010 Dec 15; 24(24):2760-5. Barish GD, Yu RT, Karunasiri M, Ocampo CB, Dixon J, Benner C, Dent AL, Tangirala RK, Evans RM. PMID: 21106671; PMCID: PMC3003193.
      View in: PubMed   Mentions: 145     Fields:    Translation:AnimalsCells
    103. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12. Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PMID: 20622854; PMCID: PMC3059551.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansCells
    104. Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol Cell Biol. 2010 Aug; 30(16):3943-55. Stender JD, Kim K, Charn TH, Komm B, Chang KC, Kraus WL, Benner C, Glass CK, Katzenellenbogen BS. PMID: 20547749; PMCID: PMC2916448.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    105. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol. 2010 Jul; 11(7):635-43. Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C. PMID: 20543837; PMCID: PMC2896911.
      View in: PubMed   Mentions: 280     Fields:    Translation:AnimalsCells
    106. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell. 2010 May 28; 38(4):576-89. Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. PMID: 20513432; PMCID: PMC2898526.
      View in: PubMed   Mentions: 4806     Fields:    Translation:AnimalsCells
    107. Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia. Circ Res. 2010 Jul 09; 107(1):56-65. Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. PMID: 20489162; PMCID: PMC2904601.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    108. General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells. Cancer Res. 2010 Feb 15; 70(4):1398-407. Gebhard C, Benner C, Ehrich M, Schwarzfischer L, Schilling E, Klug M, Dietmaier W, Thiede C, Holler E, Andreesen R, Rehli M. PMID: 20145141.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    109. Transcriptional effects of colony-stimulating factor-1 in mouse macrophages. Immunobiology. 2010 Jun; 215(6):466-74. El Chartouni C, Benner C, Eigner M, Lichtinger M, Rehli M. PMID: 19758725.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    110. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93. Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. PMID: 19299558; PMCID: PMC2661610.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    111. In silico discovery of transcription regulatory elements in Plasmodium falciparum. BMC Genomics. 2008 Feb 07; 9:70. Young JA, Johnson JR, Benner C, Yan SF, Chen K, Le Roch KG, Zhou Y, Winzeler EA. PMID: 18257930; PMCID: PMC2268928.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    112. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007 Jun; 117(6):1658-69. Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. PMID: 17525798; PMCID: PMC1868788.
      View in: PubMed   Mentions: 233     Fields:    Translation:AnimalsCells
    113. Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):4852-7. Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. PMID: 17360330; PMCID: PMC1821125.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    114. Systems biology of macrophages. Adv Exp Med Biol. 2007; 598:62-79. Maurya MR, Benner C, Pradervand S, Glass C, Subramaniam S. PMID: 17892205.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    115. Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res. 2006 May; 47(5):1097-111. Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC, Buczynski MW, Cooper JA, Deems RA, Dennis EA. PMID: 16479018.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    116. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21. Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. PMID: 16143103; PMCID: PMC1430687.
      View in: PubMed   Mentions: 252     Fields:    Translation:AnimalsCells
    117. Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays. BMC Bioinformatics. 2004 Apr 20; 5:42. Barrera L, Benner C, Tao YC, Winzeler E, Zhou Y. PMID: 15099405; PMCID: PMC411067.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
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