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Michael Lam

Title(s)Assistant Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Anifrolumab treatment of Singleton-Merten syndrome 2 due to a novel RIGI variant. J Allergy Clin Immunol. 2025 Sep 05. Hsu EE, LeSon CE, Lam MT, Okada S, Yue J, Rimland CA, Weng R, Zhou Q, Geva T, Roberts AE, Ilagan C, Carreon CK, Son MBF, Lee PY. PMID: 40913606.
      View in: PubMed   Mentions:    Fields:    
    2. Treatment with intravenous immunoglobulin modulates coagulation- and complement-related pathways in COVID-19 patients. Front Immunol. 2025; 16:1623309. McGrosso D, Raygoza J, Kumar AJ, Lam MTY, Barnes LA, Karandashova S, Perryman A, Geriak M, Odish MF, Coufal NG, Lichtenstein B, Sakoulas G, Meier A, Nizet V, Masso-Silva JA. PMID: 40821834; PMCID: PMC12350128.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. T-ing up the storm: pathogenic cycling lymphocytes in the biology of macrophage activation syndrome. Pediatr Rheumatol Online J. 2025 Mar 17; 23(1):29. Lam MT, Jiang CL, Lee PY. PMID: 40098189; PMCID: PMC11912701.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. J Allergy Clin Immunol. 2025 Apr; 155(4):1346-1356.e9. Liu M, Brodeur KE, Bledsoe JR, Harris CN, Joerger J, Weng R, Hsu EE, Lam MT, Rimland CA, LeSon CE, Yue J, Henderson LA, Dedeoglu F, Newburger JW, Nigrovic PA, Son MBF, Lee PY. PMID: 39622297.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    5. Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients. Cell Rep Med. 2023 02 21; 4(2):100935. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 36758547; PMCID: PMC9874047.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    6. Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis. Front Mol Biosci. 2022; 9:1051471. Dos Santos F, Li JB, Juocys N, Mazor R, Beretta L, Coufal NG, Lam MTY, Odish MF, Irigoyen MC, O'Donoghue AJ, Aletti F, Kistler EB. PMID: 36710882; PMCID: PMC9874325.
      View in: PubMed   Mentions: 1  
    7. Absolute quantification of plasma mitochondrial DNA by droplet digital PCR marks COVID-19 severity over time during intensive care unit admissions. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L84-L92. Hepokoski ML, Odish M, Lam MT, Coufal NG, Rolfsen ML, Shadel GS, Moyzis AG, Sainz AG, Takiar PG, Patel S, Leonard AJ, Samandari N, Hansen E, Trescott S, Nguyen C, Jepsen K, Cutter G, Gillespie MN, Spragg RG, Sasik R, Ix JH. PMID: 35699291; PMCID: PMC9273271.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    8. Correction to: Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 May 30; 74(10):1889-1890. Masso-Silva JA, Moshensky A, Lam MTY, Odish M, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott R, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 35416961; PMCID: PMC9327099.
      View in: PubMed   Mentions: 5     Fields:    
    9. Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 02 11; 74(3):479-489. Masso-Silva JA, Moshensky A, Lam MTY, Odish MF, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott RK, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 33988226; PMCID: PMC8241438.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    10. Rubella Virus Infected Macrophages and Neutrophils Define Patterns of Granulomatous Inflammation in Inborn and Acquired Errors of Immunity. Front Immunol. 2021; 12:796065. Perelygina L, Faisthalab R, Abernathy E, Chen MH, Hao L, Bercovitch L, Bayer DK, Noroski LM, Lam MT, Cicalese MP, Al-Herz W, Nanda A, Hajjar J, Vanden Driessche K, Schroven S, Leysen J, Rosenbach M, Peters P, Raedler J, Albert MH, Abraham RS, Rangarjan HG, Buchbinder D, Kobrynski L, Pham-Huy A, Dhossche J, Cunningham Rundles C, Meyer AK, Theos A, Atkinson TP, Musiek A, Adeli M, Derichs U, Walz C, Krüger R, von Bernuth H, Klein C, Icenogle J, Hauck F, Sullivan KE. PMID: 35003119; PMCID: PMC8728873.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    11. Searching for Gravitational Waves from Cosmological Phase Transitions with the NANOGrav 12.5-Year Dataset. Phys Rev Lett. 2021 Dec 17; 127(25):251302. Arzoumanian Z, Baker PT, Blumer H, Bécsy B, Brazier A, Brook PR, Burke-Spolaor S, Charisi M, Chatterjee S, Chen S, Cordes JM, Cornish NJ, Crawford F, Cromartie HT, DeCesar ME, Demorest PB, Dolch T, Ellis JA, Ferrara EC, Fiore W, Fonseca E, Garver-Daniels N, Gentile PA, Good DC, Hazboun JS, Holgado AM, Islo K, Jennings RJ, Jones ML, Kaiser AR, Kaplan DL, Kelley LZ, Key JS, Laal N, Lam MT, Lazio TJW, Lee VSH, Lorimer DR, Luo J, Lynch RS, Madison DR, McLaughlin MA, Mingarelli CMF, Mitridate A, Ng C, Nice DJ, Pennucci TT, Pol NS, Ransom SM, Ray PS, Shapiro-Albert BJ, Siemens X, Simon J, Spiewak R, Stairs IH, Stinebring DR, Stovall K, Sun JP, Swiggum JK, Taylor SR, Turner JE, Vallisneri M, Vigeland SJ, Witt CA, Zurek KM, NANOGrav Collaboration. PMID: 35029450.
      View in: PubMed   Mentions: 2     Fields:    
    12. Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19. bioRxiv. 2021 Aug 24. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 34462742; PMCID: PMC8404884.
      View in: PubMed   Mentions: 3  
    13. ATS Core Curriculum 2020. Adult Sleep Medicine. ATS Sch. 2020 Dec 30; 1(4):476-494. Jamil SM, Owens RL, Lipford MC, Shafazand S, Marron RM, Vega Sanchez ME, Lam MT, Sunwoo BY, Schmickl C, Orr JE, Sharma S, Sankari A, Javaheri S, Bertisch S, Dupuy-McCauley K, Kolla B, Imayama I, Prasad B, Guzman E, Hayes MM, Wang T. PMID: 33870314; PMCID: PMC8015760.
      View in: PubMed   Mentions: 1     Fields:    
    14. Design and Implementation of NK Cell-Based Immunotherapy to Overcome the Solid Tumor Microenvironment. Cancers (Basel). 2020 Dec 21; 12(12). Navin I, Lam MT, Parihar R. PMID: 33371456; PMCID: PMC7767468.
      View in: PubMed   Mentions: 18  
    15. OSA as a probable risk factor for severe COVID-19. J Clin Sleep Med. 2020 09 15; 16(9):1649. McSharry D, Lam MT, Malhotra A. PMID: 32713422; PMCID: PMC7970598.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    16. A research-driven approach to the identification of novel natural killer cell deficiencies affecting cytotoxic function. Blood. 2020 02 27; 135(9):629-637. Lam MT, Mace EM, Orange JS. PMID: 31945148; PMCID: PMC7046607.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    17. Use of Electronic Cigarettes with Conventional Tobacco Is Associated with Decreased Sleep Quality in Women. Am J Respir Crit Care Med. 2019 12 01; 200(11):1431-1434. Boddu SA, Bojanowski CM, Lam MT, Advani IN, Scholten EL, Sun X, Montgrain P, Malhotra A, Jain S, Alexander LEC. PMID: 31314572; PMCID: PMC6884046.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    18. A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. J Exp Med. 2019 12 02; 216(12):2778-2799. Lam MT, Coppola S, Krumbach OHF, Prencipe G, Insalaco A, Cifaldi C, Brigida I, Zara E, Scala S, Di Cesare S, Martinelli S, Di Rocco M, Pascarella A, Niceta M, Pantaleoni F, Ciolfi A, Netter P, Carisey AF, Diehl M, Akbarzadeh M, Conti F, Merli P, Pastore A, Levi Mortera S, Camerini S, Farina L, Buchholzer M, Pannone L, Cao TN, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Gibbs RA, Basso-Ricci L, Chiriaco M, Dvorsky R, Putignani L, Carsetti R, Janning P, Stray-Pedersen A, Erichsen HC, Horne A, Bryceson YT, Torralba-Raga L, Ramme K, Rosti V, Bracaglia C, Messia V, Palma P, Finocchi A, Locatelli F, Chinn IK, Lupski JR, Mace EM, Cancrini C, Aiuti A, Ahmadian MR, Orange JS, De Benedetti F, Tartaglia M. PMID: 31601675; PMCID: PMC6888978.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    19. Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment. Trends Cancer. 2019 08; 5(8):475-494. Sulli G, Lam MTY, Panda S. PMID: 31421905; PMCID: PMC7120250.
      View in: PubMed   Mentions: 222     Fields:    Translation:Humans
    20. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife. 2017 06 06; 6. Hogan NT, Whalen MB, Stolze LK, Hadeli NK, Lam MT, Springstead JR, Glass CK, Romanoski CE. PMID: 28585919; PMCID: PMC5461113.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    21. SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab. 2017 02 07; 25(2):412-427. Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. PMID: 28041958; PMCID: PMC5568699.
      View in: PubMed   Mentions: 192     Fields:    Translation:AnimalsCells
    22. Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 2016 07 27; 5. Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. PMID: 27462873; PMCID: PMC4963201.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    23. Lungs can tell time-a highlight from 2016 ATS session on clock genes, inflammation, immunology, and sleep. J Thorac Dis. 2016 Jul; 8(Suppl 7):S579-81. Lam MT, Grandner MA, Malhotra A. PMID: 27606100; PMCID: PMC4990684.
      View in: PubMed   Mentions:
    24. Timing Matters: Circadian Rhythm in Sepsis, Obstructive Lung Disease, Obstructive Sleep Apnea, and Cancer. Ann Am Thorac Soc. 2016 07; 13(7):1144-54. Truong KK, Lam MT, Grandner MA, Sassoon CS, Malhotra A. PMID: 27104378; PMCID: PMC5015754.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    25. Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82. Lam MT, Li W, Rosenfeld MG, Glass CK. PMID: 24674738; PMCID: PMC4266492.
      View in: PubMed   Mentions: 280     Fields:    Translation:HumansAnimalsCells
    26. Enhancer RNAs. Cell Cycle. 2014; 13(20):3151-2. Li W, Lam MT, Notani D. PMID: 25485487; PMCID: PMC4613994.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    27. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23. Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. PMID: 24189069; PMCID: PMC3861632.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    28. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5. Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. PMID: 23728303; PMCID: PMC3839578.
      View in: PubMed   Mentions: 345     Fields:    Translation:AnimalsCells
    29. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 2012 Mar 29; 485(7396):123-7. Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. PMID: 22460952; PMCID: PMC3367514.
      View in: PubMed   Mentions: 582     Fields:    Translation:AnimalsCells
    30. PPARs and lipid ligands in inflammation and metabolism. Chem Rev. 2011 Oct 12; 111(10):6321-40. Harmon GS, Lam MT, Glass CK. PMID: 21988241; PMCID: PMC3437919.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    31. Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res. 2011 Jun 01; 90(3):430-40. Kaikkonen MU, Lam MT, Glass CK. PMID: 21558279; PMCID: PMC3096308.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansAnimalsCells
    32. Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10901-6. Murphy PA, Lam MT, Wu X, Kim TN, Vartanian SM, Bollen AW, Carlson TR, Wang RA. PMID: 18667694; PMCID: PMC2504798.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    33. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12; 102(28):9884-9. Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ, Messina LM, Capobianco AJ, Werb Z, Wang R. PMID: 15994223; PMCID: PMC1175015.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
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