Michael Lam

Title(s)	Assistant Professor In Residence, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients. Cell Rep Med. 2023 02 21; 4(2):100935. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 36758547; PMCID: PMC9874047.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)
Translation:Humans Cells
Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis. Front Mol Biosci. 2022; 9:1051471. Dos Santos F, Li JB, Juocys N, Mazor R, Beretta L, Coufal NG, Lam MTY, Odish MF, Irigoyen MC, O'Donoghue AJ, Aletti F, Kistler EB. PMID: 36710882; PMCID: PMC9874325.

View in: PubMed Mentions:
Absolute quantification of plasma mitochondrial DNA by droplet digital PCR marks COVID-19 severity over time during intensive care unit admissions. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L84-L92. Hepokoski ML, Odish M, Lam MT, Coufal NG, Rolfsen ML, Shadel GS, Moyzis AG, Sainz AG, Takiar PG, Patel S, Leonard AJ, Samandari N, Hansen E, Trescott S, Nguyen C, Jepsen K, Cutter G, Gillespie MN, Spragg RG, Sasik R, Ix JH. PMID: 35699291; PMCID: PMC9273271.

View in: PubMed Mentions: 5 Fields:
Cel Cell Biology Mol Molecular Biology Phy Physiology Pul Pulmonary Medicine
Translation:Humans
Correction to: Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 May 30; 74(10):1889-1890. Masso-Silva JA, Moshensky A, Lam MTY, Odish M, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott R, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 35416961; PMCID: PMC9327099.

View in: PubMed Mentions: 4 Fields:
Com Communicable Diseases
Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature. Clin Infect Dis. 2022 02 11; 74(3):479-489. Masso-Silva JA, Moshensky A, Lam MTY, Odish MF, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott RK, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. PMID: 33988226; PMCID: PMC8241438.

View in: PubMed Mentions: 60 Fields:
Com Communicable Diseases
Translation:Humans Cells
Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19. bioRxiv. 2021 Aug 24. Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. PMID: 34462742; PMCID: PMC8404884.

View in: PubMed Mentions: 3
ATS Core Curriculum 2020. Adult Sleep Medicine. ATS Sch. 2020 Dec 30; 1(4):476-494. Jamil SM, Owens RL, Lipford MC, Shafazand S, Marron RM, Vega Sanchez ME, Lam MT, Sunwoo BY, Schmickl C, Orr JE, Sharma S, Sankari A, Javaheri S, Bertisch S, Dupuy-McCauley K, Kolla B, Imayama I, Prasad B, Guzman E, Hayes MM, Wang T. PMID: 33870314; PMCID: PMC8015760.

View in: PubMed Mentions:
OSA as a probable risk factor for severe COVID-19. J Clin Sleep Med. 2020 09 15; 16(9):1649. McSharry D, Lam MT, Malhotra A. PMID: 32713422; PMCID: PMC7970598.

View in: PubMed Mentions: 8 Fields:
Neu Neurology Psy Psychophysiology
Translation:Humans Cells PHPublic Health
Use of Electronic Cigarettes with Conventional Tobacco Is Associated with Decreased Sleep Quality in Women. Am J Respir Crit Care Med. 2019 12 01; 200(11):1431-1434. Boddu SA, Bojanowski CM, Lam MT, Advani IN, Scholten EL, Sun X, Montgrain P, Malhotra A, Jain S, Alexander LEC. PMID: 31314572; PMCID: PMC6884046.

View in: PubMed Mentions: 10 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. J Exp Med. 2019 12 02; 216(12):2778-2799. Lam MT, Coppola S, Krumbach OHF, Prencipe G, Insalaco A, Cifaldi C, Brigida I, Zara E, Scala S, Di Cesare S, Martinelli S, Di Rocco M, Pascarella A, Niceta M, Pantaleoni F, Ciolfi A, Netter P, Carisey AF, Diehl M, Akbarzadeh M, Conti F, Merli P, Pastore A, Levi Mortera S, Camerini S, Farina L, Buchholzer M, Pannone L, Cao TN, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Gibbs RA, Basso-Ricci L, Chiriaco M, Dvorsky R, Putignani L, Carsetti R, Janning P, Stray-Pedersen A, Erichsen HC, Horne A, Bryceson YT, Torralba-Raga L, Ramme K, Rosti V, Bracaglia C, Messia V, Palma P, Finocchi A, Locatelli F, Chinn IK, Lupski JR, Mace EM, Cancrini C, Aiuti A, Ahmadian MR, Orange JS, De Benedetti F, Tartaglia M. PMID: 31601675; PMCID: PMC6888978.

View in: PubMed Mentions: 79 Fields:
All Allergy and Immunology Med Medicine (General)
Translation:Humans Animals Cells
Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment. Trends Cancer. 2019 08; 5(8):475-494. Sulli G, Lam MTY, Panda S. PMID: 31421905; PMCID: PMC7120250.

View in: PubMed Mentions: 153 Fields:
Neo Neoplasms
Translation:Humans
Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife. 2017 06 06; 6. Hogan NT, Whalen MB, Stolze LK, Hadeli NK, Lam MT, Springstead JR, Glass CK, Romanoski CE. PMID: 28585919; PMCID: PMC5461113.

View in: PubMed Mentions: 49 Fields:
Bio Biology
Translation:Humans Cells
SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab. 2017 02 07; 25(2):412-427. Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. PMID: 28041958; PMCID: PMC5568699.

View in: PubMed Mentions: 156 Fields:
Cel Cell Biology Met Metabolism
Translation:Animals Cells
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 2016 07 27; 5. Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. PMID: 27462873; PMCID: PMC4963201.

View in: PubMed Mentions: 41 Fields:
Bio Biology
Translation:Animals Cells
Lungs can tell time-a highlight from 2016 ATS session on clock genes, inflammation, immunology, and sleep. J Thorac Dis. 2016 Jul; 8(Suppl 7):S579-81. Lam MT, Grandner MA, Malhotra A. PMID: 27606100; PMCID: PMC4990684.

View in: PubMed Mentions:
Timing Matters: Circadian Rhythm in Sepsis, Obstructive Lung Disease, Obstructive Sleep Apnea, and Cancer. Ann Am Thorac Soc. 2016 07; 13(7):1144-54. Truong KK, Lam MT, Grandner MA, Sassoon CS, Malhotra A. PMID: 27104378; PMCID: PMC5015754.

View in: PubMed Mentions: 38 Fields:
Pul Pulmonary Medicine
Translation:Humans
Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82. Lam MT, Li W, Rosenfeld MG, Glass CK. PMID: 24674738; PMCID: PMC4266492.

View in: PubMed Mentions: 262 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Enhancer RNAs. Cell Cycle. 2014; 13(20):3151-2. Li W, Lam MT, Notani D. PMID: 25485487; PMCID: PMC4613994.

View in: PubMed Mentions: 11 Fields:
Cel Cell Biology
Translation:Humans
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23. Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. PMID: 24189069; PMCID: PMC3861632.

View in: PubMed Mentions: 39 Fields:
Bio Biochemistry
Translation:Animals Cells
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5. Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. PMID: 23728303; PMCID: PMC3839578.

View in: PubMed Mentions: 322 Fields:
Sci Science
Translation:Animals Cells
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 2012 Mar 29; 485(7396):123-7. Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. PMID: 22460952; PMCID: PMC3367514.

View in: PubMed Mentions: 521 Fields:
Sci Science
Translation:Animals Cells
PPARs and lipid ligands in inflammation and metabolism. Chem Rev. 2011 Oct 12; 111(10):6321-40. Harmon GS, Lam MT, Glass CK. PMID: 21988241; PMCID: PMC3437919.

View in: PubMed Mentions: 67 Fields:
Che Chemistry
Translation:Animals Cells
Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res. 2011 Jun 01; 90(3):430-40. Kaikkonen MU, Lam MT, Glass CK. PMID: 21558279; PMCID: PMC3096308.

View in: PubMed Mentions: 242 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Humans Animals Cells
Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10901-6. Murphy PA, Lam MT, Wu X, Kim TN, Vartanian SM, Bollen AW, Carlson TR, Wang RA. PMID: 18667694; PMCID: PMC2504798.

View in: PubMed Mentions: 72 Fields:
Sci Science
Translation:Animals Cells
Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12; 102(28):9884-9. Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ, Messina LM, Capobianco AJ, Werb Z, Wang R. PMID: 15994223; PMCID: PMC1175015.

View in: PubMed Mentions: 88 Fields:
Sci Science
Translation:Animals Cells