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Yoshitake Cho

Title(s)Associate Project Scientist, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    The University of TokyoPh.D.
    Collapse Awards and Honors
    American Heart Association2014  - 2017Scientist Development Grant
    American Heart Association2012  - 2013Postdoctoral Fellowship
    California Institute of Regenerative Medicine2009  - 2011Postdoctoral Fellowship

    Collapse Research 
    Collapse Research Activities and Funding
    PERM in Cardiac Function
    NIH/NHLBI R01HL151239Jan 1, 2020 - Dec 31, 2023
    Role: Co-Principal Investigator
    The role of Perm1 in integrating and transducing contraction-induced signals to adaptive responses in skeletal muscle
    American Heart Association 14SDG17790005Jan 1, 2014 - Jan 31, 2017
    Role: Principal Investigator
    Role of the novel tissue-specific PGC-1 and ERR target gene PERM1 in muscle
    American Heart Association 12POST8610009Jan 1, 2012 - Jan 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Perm1 regulates CaMKII activation and shapes skeletal muscle responses to endurance exercise training. Mol Metab. 2019 05; 23:88-97. Cho Y, Tachibana S, Hazen BC, Moresco JJ, Yates JR, Kok B, Saez E, Ross RS, Russell AP, Kralli A. PMID: 30862473.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Analyzing Oxygen Consumption Rate in Primary Cultured Mouse Neonatal Cardiomyocytes Using an Extracellular Flux Analyzer. J Vis Exp. 2019 02 13; (144). Tachibana S, Chen C, Zhang OR, Schurr SV, Hill C, Li R, Manso AM, Zhang J, Andreyev A, Murphy AN, Ross RS, Cho Y. PMID: 30829322.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II d Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling. Circulation. 2018 11 27; 138(22):2530-2544. Suetomi T, Willeford A, Brand CS, Cho Y, Ross RS, Miyamoto S, Brown JH. PMID: 30571348.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    4. A mini review: Proteomics approaches to understand disused vs. exercised human skeletal muscle. Physiol Genomics. 2018 09 01; 50(9):746-757. Cho Y, Ross RS. PMID: 29958080.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    5. Perm1 enhances mitochondrial biogenesis, oxidative capacity, and fatigue resistance in adult skeletal muscle. FASEB J. 2016 Feb; 30(2):674-87. Cho Y, Hazen BC, Gandra PG, Ward SR, Schenk S, Russell AP, Kralli A. PMID: 26481306.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    6. PGC-1a and PGC-1ß increase CrT expression and creatine uptake in myotubes via ERRa. Biochim Biophys Acta. 2014 Dec; 1843(12):2937-43. Brown EL, Snow RJ, Wright CR, Cho Y, Wallace MA, Kralli A, Russell AP. PMID: 25173818.
      View in: PubMed   Mentions: 6     Fields:    
    7. Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes. Virology. 2014 Jun; 458-459:22-32. Iwasaki M, Urata S, Cho Y, Ngo N, de la Torre JC. PMID: 24928036.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    8. Ndrg2 is a PGC-1a/ERRa target gene that controls protein synthesis and expression of contractile-type genes in C2C12 myotubes. Biochim Biophys Acta. 2013 Dec; 1833(12):3112-3123. Foletta VC, Brown EL, Cho Y, Snow RJ, Kralli A, Russell AP. PMID: 24008097.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Peroxisome proliferator-activated receptor ? coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells. J Biol Chem. 2013 Aug 30; 288(35):25207-18. Cho Y, Hazen BC, Russell AP, Kralli A. PMID: 23836911.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    10. Enhanced oxidative stress in GH-transgenic rat and acromegaly in humans. Growth Horm IGF Res. 2012 Apr; 22(2):64-8. Nishizawa H, Handayaningsih AE, Iguchi G, Cho Y, Takahashi M, Yamamoto M, Suda K, Kasahara K, Hakuno F, Yamanouchi K, Nishihara M, Seino S, Takahashi S, Takahashi Y. PMID: 22370764.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    11. Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases. Biochem Biophys Res Commun. 2011 Jan 21; 404(3):767-73. Fukushima T, Arai T, Ariga-Nedachi M, Okajima H, Ooi Y, Iijima Y, Sone M, Cho Y, Ando Y, Kasahara K, Ozoe A, Yoshihara H, Chida K, Okada S, Kopchick JJ, Asano T, Hakuno F, Takahashi S. PMID: 21168390.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    12. Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity. Biochem Biophys Res Commun. 2010 Apr 09; 394(3):697-702. Kabuta T, Hakuno F, Cho Y, Yamanaka D, Chida K, Asano T, Wada K, Takahashi S. PMID: 20226764.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    13. Effect of paraquat-induced oxidative stress on insulin regulation of insulin-like growth factor-binding protein-1 gene expression. J Clin Biochem Nutr. 2010 Mar; 46(2):157-67. Kimura K, Katsumata Y, Ozawa T, Tawara S, Igarashi K, Cho Y, Shibata N, Hakuno F, Takahashi S, Takenaka A. PMID: 20216949.
      View in: PubMed   Mentions:
    14. DEC functions as Nuclear Receptor Compressor. Chem-Bio Informatics Society (CBI) Journal (Japanese). 2010; (3):1-6. Yoshitake Cho, Mitsuhide Noshiro, Makoto Makishima.
    15. The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. Mol Pharmacol. 2009 Dec; 76(6):1360-9. Cho Y, Noshiro M, Choi M, Morita K, Kawamoto T, Fujimoto K, Kato Y, Makishima M. PMID: 19786558.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    16. Induction of SREBP-1c mRNA by differentiation and LXR ligand in human keratinocytes. J Invest Dermatol. 2009 Jun; 129(6):1395-401. Yokoyama A, Makishima M, Choi M, Cho Y, Nishida S, Hashimoto Y, Terui T. PMID: 19242521.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells. J Steroid Biochem Mol Biol. 2009 Apr; 114(3-5):144-51. Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M. PMID: 19429444.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    18. The novel roles of liver for compensation of insulin resistance in human growth hormone transgenic rats. Endocrinology. 2006 Nov; 147(11):5374-84. Cho Y, Ariga M, Uchijima Y, Kimura K, Rho JY, Furuhata Y, Hakuno F, Yamanouchi K, Nishihara M, Takahashi S. PMID: 16916956.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    19. Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes. Biochim Biophys Acta. 2005 Oct 15; 1737(1):36-43. Tachibana S, Sato K, Cho Y, Chiba T, Schneider WJ, Akiba Y. PMID: 16226916.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    20. Impairment of VLDL secretion by medium-chain fatty acids in chicken primary hepatocytes is affected by the chain length. J Nutr. 2005 Jul; 135(7):1636-41. Sato K, Cho Y, Tachibana S, Chiba T, Schneider WJ, Akiba Y. PMID: 15987842.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells