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Amir Zarrinpar

Title(s)Assistant Professor In Residence, Medicine
SchoolHealth Sciences
Phone858-246-1665
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    Collapse Biography 
    Collapse Awards and Honors
    AGA2014  - 2016AGA Microbiome Junior Investigator Research Award
    AASLD2014  - 2017Liver Scholar Award
    Larry L. Hillblom Foundation2014  - 2014Larry L. Hillblom Foundation Award Seed Grant (could not hold with Liver Scholar Award)
    UCSD - CTRI2014  - 2014UCSD KL2 Grant (could not hold with Liver Scholar Award)
    AGA2013  - 2014AGA Elsevier Pilot Research Grant
    Salix Inc.2013  - 2013Fellowship2Leadership Fellow

    Collapse Overview 
    Collapse Overview
    As the health burden of obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD) increases, I hope to perform high impact research investigating novel therapeutic pathways in these diseases that, as of yet, have few curative options.

    Collapse Research 
    Collapse Research Activities and Funding
    The Role of Altered Luminal Dynamics in OSA-Induced Atherosclerosis
    NIH/NHLBI R01HL148801Jul 10, 2019 - Jun 30, 2024
    Role: Principal Investigator
    The effect of luminal bile acid biotransformations on host cognition
    NIH/NIMH R21MH117780Jul 1, 2018 - May 31, 2020
    Role: Principal Investigator
    The Effects of Bile Acid Conjugation Through Engineered Probiotics on Gut Luminal signaling and Metabolism
    NIH/NIDDK R03DK114536Aug 1, 2017 - Jul 31, 2019
    Role: Principal Investigator
    The Relationship of Gut Microbiome and Time Restricted Feeding in Metabolism
    NIH/NIDDK K08DK102902Sep 30, 2015 - Jul 31, 2020
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Saran AR, Dave S, Zarrinpar A. Circadian Rhythms in the Pathogenesis and Treatment of Fatty Liver Disease. Gastroenterology. 2020 Feb 13. PMID: 32061597.
      View in: PubMed
    2. Huang S, Haiminen N, Carrieri AP, Hu R, Jiang L, Parida L, Russell B, Allaband C, Zarrinpar A, Vázquez-Baeza Y, Belda-Ferre P, Zhou H, Kim HC, Swafford AD, Knight R, Xu ZZ. Human Skin, Oral, and Gut Microbiomes Predict Chronological Age. mSystems. 2020 Feb 11; 5(1). PMID: 32047061.
      View in: PubMed
    3. Thompson CC, Abu Dayyeh BK, Kushnir V, Kushner RF, Jirapinyo P, Schorr AB, Aronne LJ, Amaro A, Jaffe DL, Schulman AR, Early D, Stein AC, Sharaiha R, Edmundowicz SA, Bohning JM, Jensen MD, Shukla AP, Apovian C, Kim DW, Tran D, Zarrinpar A, Ryan MB, Young M, Lowe A, Haas M, Goldsmith H, McCrea J, Sullivan S. Aspiration therapy for the treatment of obesity: 4-year results of a multicenter randomized controlled trial. Surg Obes Relat Dis. 2019 Aug; 15(8):1348-1354. PMID: 31302000.
      View in: PubMed
    4. Desalermos A, Russell B, Leggett C, Parnell A, Ober K, Hagerich K, Gerlan C, Ganji G, Lee E, Proudfoot JA, Grunvald E, Gupta S, Ho SB, Zarrinpar A. Effect of Obesogenic Medications on Weight-Loss Outcomes in a Behavioral Weight-Management Program. Obesity (Silver Spring). 2019 05; 27(5):716-723. PMID: 31012292.
      View in: PubMed
    5. Leggett CB, Desalermos A, Brown SD, Lee E, Proudfoot JA, Horgan S, Gupta S, Grunvald E, Ho SB, Zarrinpar A. The effects of provider-prescribed obesogenic drugs on post-laparoscopic sleeve gastrectomy outcomes: a retrospective cohort study. Int J Obes (Lond). 2019 06; 43(6):1154-1163. PMID: 30242239.
      View in: PubMed
    6. Allaband C, McDonald D, Vázquez-Baeza Y, Minich JJ, Tripathi A, Brenner DA, Loomba R, Smarr L, Sandborn WJ, Schnabl B, Dorrestein P, Zarrinpar A, Knight R. Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians. Clin Gastroenterol Hepatol. 2019 01; 17(2):218-230. PMID: 30240894.
      View in: PubMed
    7. Zarrinpar A, Chaix A, Xu ZZ, Chang MW, Marotz CA, Saghatelian A, Knight R, Panda S. Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism. Nat Commun. 2018 07 20; 9(1):2872. PMID: 30030441.
      View in: PubMed
    8. Singh S, Facciorusso A, Singh AG, Vande Casteele N, Zarrinpar A, Prokop LJ, Grunvald EL, Curtis JR, Sandborn WJ. Obesity and response to anti-tumor necrosis factor-a agents in patients with select immune-mediated inflammatory diseases: A systematic review and meta-analysis. PLoS One. 2018; 13(5):e0195123. PMID: 29771924.
      View in: PubMed
    9. Kurnool S, Nguyen NH, Proudfoot J, Dulai PS, Boland BS, Vande Casteele N, Evans E, Grunvald EL, Zarrinpar A, Sandborn WJ, Singh S. High body mass index is associated with increased risk of treatment failure and surgery in biologic-treated patients with ulcerative colitis. Aliment Pharmacol Ther. 2018 06; 47(11):1472-1479. PMID: 29665045.
      View in: PubMed
    10. Thompson CC, Abu Dayyeh BK, Kushner R, Sullivan S, Schorr AB, Amaro A, Apovian CM, Fullum T, Zarrinpar A, Jensen MD, Stein AC, Edmundowicz S, Kahaleh M, Ryou M, Bohning JM, Ginsberg G, Huang C, Tran DD, Glaser JP, Martin JA, Jaffe DL, Farraye FA, Ho SB, Kumar N, Harakal D, Young M, Thomas CE, Shukla AP, Ryan MB, Haas M, Goldsmith H, McCrea J, Aronne LJ. Percutaneous Gastrostomy Device for the Treatment of Class II and Class III Obesity: Results of a Randomized Controlled Trial. Am J Gastroenterol. 2017 03; 112(3):447-457. PMID: 27922026.
      View in: PubMed
    11. Singh S, Dulai PS, Zarrinpar A, Ramamoorthy S, Sandborn WJ. Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes. Nat Rev Gastroenterol Hepatol. 2017 02; 14(2):110-121. PMID: 27899815.
      View in: PubMed
    12. Chaix A, Zarrinpar A, Panda S. The circadian coordination of cell biology. J Cell Biol. 2016 Oct 10; 215(1):15-25. PMID: 27738003.
      View in: PubMed
    13. Marotz CA, Zarrinpar A. Treating Obesity and Metabolic Syndrome with Fecal Microbiota Transplantation. Yale J Biol Med. 2016 09; 89(3):383-388. PMID: 27698622.
      View in: PubMed
    14. Anand G, Zarrinpar A, Loomba R. Targeting Dysbiosis for the Treatment of Liver Disease. Semin Liver Dis. 2016 Feb; 36(1):37-47. PMID: 26870931.
      View in: PubMed
    15. Zarrinpar A, Chaix A, Panda S. Daily Eating Patterns and Their Impact on Health and Disease. Trends Endocrinol Metab. 2016 Feb; 27(2):69-83. PMID: 26706567.
      View in: PubMed
    16. Zarrinpar A, Gupta S, Maurya MR, Subramaniam S, Loomba R. Serum microRNAs explain discordance of non-alcoholic fatty liver disease in monozygotic and dizygotic twins: a prospective study. Gut. 2016 09; 65(9):1546-54. PMID: 26002934.
      View in: PubMed
    17. Chaix A, Zarrinpar A. The effects of time-restricted feeding on lipid metabolism and adiposity. Adipocyte. 2015 Oct-Dec; 4(4):319-24. PMID: 26451290.
      View in: PubMed
    18. Egnatios J, Kaushal K, Kalmaz D, Zarrinpar A. Video Capsule Endoscopy in Patients with Chronic Abdominal Pain with or without Associated Symptoms: A Retrospective Study. PLoS One. 2015; 10(4):e0126509. PMID: 25893440.
      View in: PubMed
    19. Frankwich KA, Egnatios J, Kenyon ML, Rutledge TR, Liao PS, Gupta S, Herbst KL, Zarrinpar A. Differences in Weight Loss Between Persons on Standard Balanced vs Nutrigenetic Diets in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2015 Sep; 13(9):1625-1632.e1. PMID: 25769412.
      View in: PubMed
    20. Chaix A, Zarrinpar A, Miu P, Panda S. Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges. Cell Metab. 2014 Dec 02; 20(6):991-1005. PMID: 25470547.
      View in: PubMed
    21. Zarrinpar A, Chaix A, Yooseph S, Panda S. Diet and feeding pattern affect the diurnal dynamics of the gut microbiome. Cell Metab. 2014 Dec 02; 20(6):1006-17. PMID: 25470548.
      View in: PubMed
    22. Zarrinpar A, Callaway EM. Functional Local Input to Layer 5 Pyramidal Neurons in the Rat Visual Cortex. Cereb Cortex. 2016 Mar; 26(3):991-1003. PMID: 25405939.
      View in: PubMed
    23. Zarrinpar A, Lin GY, Lonergan JT. A rare cause of an ileocecal fistula in an AIDS patient. Gastrointestinal infection by Histoplasma capsulatum infection identified with internal transcribed spacer primer sets. Gastroenterology. 2013 Apr; 144(4):697, 857-8. PMID: 23499285.
      View in: PubMed
    24. Zarrinpar A, Loomba R. Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2012 Nov; 36(10):909-21. PMID: 23057494.
      View in: PubMed
    25. Hatori M, Vollmers C, Zarrinpar A, DiTacchio L, Bushong EA, Gill S, Leblanc M, Chaix A, Joens M, Fitzpatrick JA, Ellisman MH, Panda S. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab. 2012 Jun 06; 15(6):848-60. PMID: 22608008.
      View in: PubMed
    26. Zarrinpar A, Callaway EM. Local connections to specific types of layer 6 neurons in the rat visual cortex. J Neurophysiol. 2006 Mar; 95(3):1751-61. PMID: 16319201.
      View in: PubMed
    27. Zarrinpar A. MSJAMA. Quarantine. JAMA. 2003 Dec 03; 290(21):2872. PMID: 14657073.
      View in: PubMed
    28. Laeng B, Zarrinpar A, Kosslyn SM. Do separate processes identify objects as exemplars versus members of basic-level categories? Evidence from hemispheric specialization. Brain Cogn. 2003 Oct; 53(1):15-27. PMID: 14572498.
      View in: PubMed
    29. Zarrinpar A. MSJAMA. Roles for medical students in the political process. JAMA. 2003 Oct 01; 290(13):1774. PMID: 14519714.
      View in: PubMed
    30. Zarrinpar A. Psychiatry and stigmatization. JAMA. 2002 Apr 10; 287(14):1856. PMID: 11939874.
      View in: PubMed
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