Loading...

Patricia Thistlethwaite

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9300 Campus Point Drive #7892
La Jolla CA 92037
Phone858-657-7777
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Research

    Our lab focuses on understanding the molecular mechanism of pulmonary arterial hypertension and coronary vascular development. We are interested in how arteries and veins are specified and how vessels develop normal and pathologic smooth muscle cell investment.

    Research Topics

  • Angiogenesis

  • Cardiovascular Disease

  • Cell Biology

  • Development

  • Molecular Biology

  • Translational Research


  • Current Project Titles

  • The role of Notch3 signaling in pulmonary arterial hypertension

  • ERG-APJ signaling influences the development of pulmonary veno-occlusive disease in humans and mice

  • Molecular signals controlling coronary artery and venous development


  • Profile

    Dr. Patricia A. Thistlethwaite is a cardiothoracic surgeon and researcher who specializes in adult cardiac surgery and molecular biology. She performs the full range of cardiothoracic surgeries including heart and lung transplantation, coronary artery bypass surgery, valve repair and replacement, and general thoracic operations.

    Dr. Thistlethwaite is head of a molecular biology laboratory in the Division of Cardiothoracic Surgery. Her research focuses on molecular causes of pulmonary hypertension, mechanisms of coronary arterial and venous differentiation and angiogenesis, and the genetics of cardiac development. She leads a number of major investigations including several National Institutes of Health-funded studies and a Center for Medical Research and Education Fund (CMREF) project studying the causes, prevention, and treatment of pulmonary arterial hypertension.

    Dr. Thistlethwaite also collaborates with Dr. Jason Yuan of the Division of Pulmonary and Critical Care Medicine in the UC San Diego Department of Medicine in two NIH basic science studies, one on the genetic basis of idiopathic pulmonary arterial hypertension and one on the molecular biology of the lung. In addition, she collaborates with Dr. Paul Insel in the Department of Pharmacology in investigating caveolae expression in pulmonary vascular remodeling.

    As Program Director of the UC San Diego Cardiovascular and Thoracic Surgery Residency Program, Dr. Thistlethwaite is the first woman in the United States to be a cardiothoracic surgery program director. She was elected as a member of the American Association for Thoracic Surgery, the most prestigious society for cardiothoracic surgeons, in April 2006


    Collapse Research 
    Collapse Research Activities and Funding
    Small Molecule NOTCH Inhibitors for the treatment of pulmonary hypertension
    NIH/NHLBI R01HL132225Jun 1, 2016 - Mar 31, 2020
    Role: Principal Investigator
    NOTCH3 Signaling in Pulmonary Hypertension
    NIH/NHLBI R01HL119543Sep 1, 2014 - May 31, 2019
    Role: Principal Investigator
    Molecular Mechanisms of Pulmonary Hypertension
    NIH/NHLBI R01HL070852Jul 1, 2002 - Jun 30, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Zhang J, Dong J, Martin M, He M, Gongol B, Marin TL, Chen L, Shi X, Yin Y, Shang F, Wu Y, Huang HY, Zhang J, Zhang Y, Kang J, Moya EA, Huang HD, Powell FL, Chen Z, Thistlethwaite PA, Yuan ZY, Shyy JY. AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 Mar 23. PMID: 29570986.
      View in: PubMed
    2. Thistlethwaite PA, Gower JR, Hernandez M, Zhang Y, Picel AC, Roberts AC. Needle localization of small pulmonary nodules: Lessons learned. J Thorac Cardiovasc Surg. 2018 Jan 17. PMID: 29455962.
      View in: PubMed
    3. Thistlethwaite PA. Linking Vascular Remodeling and Inflammation in Pulmonary Arterial Hypertension: Is There a Common Root Cause? Am J Respir Cell Mol Biol. 2017 07; 57(1):15-17. PMID: 28665225.
      View in: PubMed
    4. Parker KL, Thistlethwaite P, Suliman AS, Reid C, Tenenhaus M, El Khoury Z, Golts EM. Staged Repair of an Aortic Pseudoaneurysm Secondary to Delayed Methylmethacrylate Plate Migration. Ann Thorac Surg. 2017 Feb; 103(2):e139-e141. PMID: 28109373.
      View in: PubMed
    5. Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):355-67. PMID: 25569851; PMCID: PMC4566064.
    6. Mumtaz S, Alkhuziem M, Chow J, Yen A, Lin G, Harrell JH, Thistlethwaite PA. Multifocal Endobronchial Fibromas Presenting as Unilobar Emphysema. Ann Thorac Surg. 2015 Sep; 100(3):1109-11. PMID: 26354646.
      View in: PubMed
    7. Lathen C, Zhang Y, Chow J, Singh M, Lin G, Nigam V, Ashraf YA, Yuan JX, Robbins IM, Thistlethwaite PA. Response to Letter Regarding Article, "The ERG-APLNR Axis Controls Pulmonary Venule Endothelial Proliferation in Pulmonary Veno-Occlusive Disease". Circulation. 2015 Jul 14; 132(2):e17. PMID: 26169652; PMCID: PMC4624330.
    8. Thistlethwaite PA. Invited commentary. Ann Thorac Surg. 2015 Mar; 99(3):1038-9. PMID: 25742824.
      View in: PubMed
    9. Lathen C, Zhang Y, Chow J, Singh M, Lin G, Nigam V, Ashraf YA, Yuan JX, Robbins IM, Thistlethwaite PA. ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease. Circulation. 2014 Sep 30; 130(14):1179-91. PMID: 25062690; PMCID: PMC4182129.
    10. Thistlethwaite PA. Invited commentary. Ann Thorac Surg. 2014 Jun; 97(6):2025-6. PMID: 24882285.
      View in: PubMed
    11. Yamamura H, Yamamura A, Ko EA, Pohl NM, Smith KA, Zeifman A, Powell FL, Thistlethwaite PA, Yuan JX. Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol. 2014 May 01; 306(9):C871-8. PMID: 24573085; PMCID: PMC4010807.
    12. Barrett CL, Schwab RB, Jung H, Crain B, Goff DJ, Jamieson CH, Thistlethwaite PA, Harismendy O, Carson DA, Frazer KA. Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer. PLoS One. 2013; 8(3):e58714. PMID: 23527012; PMCID: PMC3604164.
    13. Thistlethwaite PA. Invited commentary. Ann Thorac Surg. 2013 Mar; 95(3):1033-4. PMID: 23438530.
      View in: PubMed
    14. Wendel M, Bazhenova L, Boshuizen R, Kolatkar A, Honnatti M, Cho EH, Marrinucci D, Sandhu A, Perricone A, Thistlethwaite P, Bethel K, Nieva J, Heuvel Mv, Kuhn P. Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology. Phys Biol. 2012 Feb; 9(1):016005. PMID: 22307026; PMCID: PMC3387995.
    15. Hölscher M, Schäfer K, Krull S, Farhat K, Hesse A, Silter M, Lin Y, Pichler BJ, Thistlethwaite P, El-Armouche A, Maier LS, Katschinski DM, Zieseniss A. Unfavourable consequences of chronic cardiac HIF-1a stabilization. Cardiovasc Res. 2012 Apr 01; 94(1):77-86. PMID: 22258630.
      View in: PubMed
    16. Thistlethwaite PA. Invited commentary. Ann Thorac Surg. 2011 Apr; 91(4):1213. PMID: 21440147.
      View in: PubMed
    17. Thistlethwaite PA, Jamieson SW. Invited commentary. Ann Thorac Surg. 2011 Apr; 91(4):1100. PMID: 21440130.
      View in: PubMed
    18. Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, Jenkins JS, Kline JA, Michaels AD, Thistlethwaite P, Vedantham S, White RJ, Zierler BK. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 2011 Apr 26; 123(16):1788-830. PMID: 21422387.
      View in: PubMed
    19. Thistlethwaite PA, Renner J, Duhamel D, Makani S, Lin GY, Jamieson SW, Harrell J. Surgical management of endobronchial inflammatory myofibroblastic tumors. Ann Thorac Surg. 2011 Feb; 91(2):367-72. PMID: 21256271.
      View in: PubMed
    20. Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1153-60. PMID: 20581168; PMCID: PMC3001257.
    21. Xue W, Cai L, Tan Y, Thistlethwaite P, Kang YJ, Li X, Feng W. Cardiac-specific overexpression of HIF-1{alpha} prevents deterioration of glycolytic pathway and cardiac remodeling in streptozotocin-induced diabetic mice. Am J Pathol. 2010 Jul; 177(1):97-105. PMID: 20566749; PMCID: PMC2893654.
    22. Thistlethwaite P. Invited commentary. Ann Thorac Surg. 2010 Mar; 89(3):835-6. PMID: 20172139.
      View in: PubMed
    23. Huang C, Zhang X, Ramil JM, Rikka S, Kim L, Lee Y, Gude NA, Thistlethwaite PA, Sussman MA, Gottlieb RA, Gustafsson AB. Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice. Circulation. 2010 Feb 09; 121(5):675-83. PMID: 20100968; PMCID: PMC2834271.
    24. Thistlethwaite PA, Li X, Zhang X. Notch signaling in pulmonary hypertension. Adv Exp Med Biol. 2010; 661:279-98. PMID: 20204737.
      View in: PubMed
    25. Li X, Zhang X, Leathers R, Makino A, Huang C, Parsa P, Macias J, Yuan JX, Jamieson SW, Thistlethwaite PA. Notch3 signaling promotes the development of pulmonary arterial hypertension. Nat Med. 2009 Nov; 15(11):1289-97. PMID: 19855400; PMCID: PMC2780347.
    26. Ressmeyer AR, Bai Y, Delmotte P, Uy KF, Thistlethwaite P, Fraire A, Sato O, Ikebe M, Sanderson MJ. Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):179-91. PMID: 19767449; PMCID: PMC2937231.
    27. Ogawa A, Firth AL, Yao W, Madani MM, Kerr KM, Auger WR, Jamieson SW, Thistlethwaite PA, Yuan JX. Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L666-76. PMID: 19633069; PMCID: PMC2770792.
    28. Tuder RM, Abman SH, Braun T, Capron F, Stevens T, Thistlethwaite PA, Haworth SG. Development and pathology of pulmonary hypertension. J Am Coll Cardiol. 2009 Jun 30; 54(1 Suppl):S3-9. PMID: 19555856.
      View in: PubMed
    29. Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol. 2009 Jun 30; 54(1 Suppl):S20-31. PMID: 19555855; PMCID: PMC2790324.
    30. Yu Y, Keller SH, Remillard CV, Safrina O, Nicholson A, Zhang SL, Jiang W, Vangala N, Landsberg JW, Wang JY, Thistlethwaite PA, Channick RN, Robbins IM, Loyd JE, Ghofrani HA, Grimminger F, Schermuly RT, Cahalan MD, Rubin LJ, Yuan JX. A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation. 2009 May 05; 119(17):2313-22. PMID: 19380626; PMCID: PMC2749566.
    31. Yao W, Firth AL, Sacks RS, Ogawa A, Auger WR, Fedullo PF, Madani MM, Lin GY, Sakakibara N, Thistlethwaite PA, Jamieson SW, Rubin LJ, Yuan JX. Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L870-8. PMID: 19286928; PMCID: PMC2692803.
    32. Blanchard DG, Malouf PJ, Gurudevan SV, Auger WR, Madani MM, Thistlethwaite P, Waltman TJ, Daniels LB, Raisinghani AB, DeMaria AN. Utility of right ventricular Tei index in the noninvasive evaluation of chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy. JACC Cardiovasc Imaging. 2009 Feb; 2(2):143-9. PMID: 19356547.
      View in: PubMed
    33. Thistlethwaite PA, Yung G, Kemp A, Osbourne S, Jamieson SW, Channick C, Harrell J. Airway stenoses after lung transplantation: incidence, management, and outcome. J Thorac Cardiovasc Surg. 2008 Dec; 136(6):1569-75. PMID: 19114208.
      View in: PubMed
    34. Thistlethwaite PA. Invited commentary. Ann Thorac Surg. 2008 Oct; 86(4):1320. PMID: 18805184.
      View in: PubMed
    35. Thistlethwaite PA, Kaneko K, Madani MM, Jamieson SW. Technique and outcomes of pulmonary endarterectomy surgery. Ann Thorac Cardiovasc Surg. 2008 Oct; 14(5):274-82. PMID: 18989242.
      View in: PubMed
    36. Thistlethwaite PA. Invited commentary. The apolipoprotein E epsilon4 allele. Ann Thorac Surg. 2008 Sep; 86(3):848. PMID: 18721572.
      View in: PubMed
    37. Kaneko K, Li X, Zhang X, Lamberti JJ, Jamieson SW, Thistlethwaite PA. Endothelial expression of bone morphogenetic protein receptor type 1a is required for atrioventricular valve formation. Ann Thorac Surg. 2008 Jun; 85(6):2090-8. PMID: 18498827.
      View in: PubMed
    38. Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA. Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension. FASEB J. 2007 Sep; 21(11):2970-9. PMID: 17470567.
      View in: PubMed
    39. Zhang S, Patel HH, Murray F, Remillard CV, Schach C, Thistlethwaite PA, Insel PA, Yuan JX. Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1202-10. PMID: 17189322.
      View in: PubMed
    40. Thistlethwaite PA, Madani MM, Kemp AD, Hartley M, Auger WR, Jamieson SW. Venovenous extracorporeal life support after pulmonary endarterectomy: indications, techniques, and outcomes. Ann Thorac Surg. 2006 Dec; 82(6):2139-45. PMID: 17126125.
      View in: PubMed
    41. Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1. Am J Physiol Lung Cell Mol Physiol. 2007 Jan; 292(1):L294-303. PMID: 16980375.
      View in: PubMed
    42. Rose SC, Thistlethwaite PA, Sewell PE, Vance RB. Lung cancer and radiofrequency ablation. J Vasc Interv Radiol. 2006 Jun; 17(6):927-51; quiz 951. PMID: 16778226.
      View in: PubMed
    43. Thistlethwaite PA, Kemp A, Du L, Madani MM, Jamieson SW. Outcomes of pulmonary endarterectomy for treatment of extreme thromboembolic pulmonary hypertension. J Thorac Cardiovasc Surg. 2006 Feb; 131(2):307-13. PMID: 16434258.
      View in: PubMed
    44. Thistlethwaite PA, Madani M, Jamieson SW. Outcomes of pulmonary endarterectomy surgery. Semin Thorac Cardiovasc Surg. 2006; 18(3):257-64. PMID: 17185189.
      View in: PubMed
    45. Sacks RS, Remillard CV, Agange N, Auger WR, Thistlethwaite PA, Yuan JX. Molecular biology of chronic thromboembolic pulmonary hypertension. Semin Thorac Cardiovasc Surg. 2006; 18(3):265-76. PMID: 17185190.
      View in: PubMed
    46. Kido M, Du L, Sullivan CC, Li X, Deutsch R, Jamieson SW, Thistlethwaite PA. Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol. 2005 Dec 06; 46(11):2116-24. PMID: 16325051.
      View in: PubMed
    47. Fantozzi I, Huang W, Zhang J, Zhang S, Platoshyn O, Remillard CV, Thistlethwaite PA, Yuan JX. Divergent effects of BMP-2 on gene expression in pulmonary artery smooth muscle cells from normal subjects and patients with idiopathic pulmonary arterial hypertension. Exp Lung Res. 2005 Oct; 31(8):783-806. PMID: 16368652; PMCID: PMC1409757.
    48. Weitzman MD, Thistlethwaite PA. Breaking the barriers to global gene delivery. Nat Biotechnol. 2005 Mar; 23(3):305-6. PMID: 15765082.
      View in: PubMed
    49. Kido M, Du L, Sullivan CC, Deutsch R, Jamieson SW, Thistlethwaite PA. Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents. J Thorac Cardiovasc Surg. 2005 Feb; 129(2):268-76. PMID: 15678035.
      View in: PubMed
    50. Yu Y, Fantozzi I, Remillard CV, Landsberg JW, Kunichika N, Platoshyn O, Tigno DD, Thistlethwaite PA, Rubin LJ, Yuan JX. Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc Natl Acad Sci U S A. 2004 Sep 21; 101(38):13861-6. PMID: 15358862; PMCID: PMC518765.
    51. Du L, Kido M, Lee DV, Rabinowitz JE, Samulski RJ, Jamieson SW, Weitzman MD, Thistlethwaite PA. Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors. Mol Ther. 2004 Sep; 10(3):604-8. PMID: 15336660.
      View in: PubMed
    52. Kunichika N, Landsberg JW, Yu Y, Kunichika H, Thistlethwaite PA, Rubin LJ, Yuan JX. Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes. Am J Respir Crit Care Med. 2004 Nov 15; 170(10):1101-7. PMID: 15317671.
      View in: PubMed
    53. Mandegar M, Thistlethwaite PA, Yuan JX. Molecular biology of primary pulmonary hypertension. Cardiol Clin. 2004 Aug; 22(3):417-29, vi. PMID: 15302361.
      View in: PubMed
    54. Thistlethwaite PA, Madani M, Jamieson SW. Pulmonary thromboendarterectomy surgery. Cardiol Clin. 2004 Aug; 22(3):467-78, vii. PMID: 15302365.
      View in: PubMed
    55. Thistlethwaite PA, Jamieson SW. Pulmonary thromboendarterectomy. Ann Thorac Surg. 2004 Aug; 78(2):746-7. PMID: 15309813.
      View in: PubMed
    56. Ingersoll-Weng E, Manecke GR, Thistlethwaite PA. Dexmedetomidine and cardiac arrest. Anesthesiology. 2004 Mar; 100(3):738-9. PMID: 15108994.
      View in: PubMed
    57. Chu D, Sullivan CC, Du L, Cho AJ, Kido M, Wolf PL, Weitzman MD, Jamieson SW, Thistlethwaite PA. A new animal model for pulmonary hypertension based on the overexpression of a single gene, angiopoietin-1. Ann Thorac Surg. 2004 Feb; 77(2):449-56; discussion 456-7. PMID: 14759414.
      View in: PubMed
    58. Chu D, Thistlethwaite PA, Sullivan CC, Grifman MS, Weitzman MD. Gene delivery to the mammalian heart using AAV vectors. Methods Mol Biol. 2004; 246:213-24. PMID: 14970595.
      View in: PubMed
    59. Jamieson SW, Kapelanski DP, Sakakibara N, Manecke GR, Thistlethwaite PA, Kerr KM, Channick RN, Fedullo PF, Auger WR. Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. Ann Thorac Surg. 2003 Nov; 76(5):1457-62; discussion 1462-4. PMID: 14602267.
      View in: PubMed
    60. Sullivan CC, Du L, Chu D, Cho AJ, Kido M, Wolf PL, Jamieson SW, Thistlethwaite PA. Induction of pulmonary hypertension by an angiopoietin 1/TIE2/serotonin pathway. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12331-6. PMID: 14512515; PMCID: PMC218758.
    61. Chu D, Sullivan CC, Weitzman MD, Du L, Wolf PL, Jamieson SW, Thistlethwaite PA. Direct comparison of efficiency and stability of gene transfer into the mammalian heart using adeno-associated virus versus adenovirus vectors. J Thorac Cardiovasc Surg. 2003 Sep; 126(3):671-9. PMID: 14502138.
      View in: PubMed
    62. Zhang S, Fantozzi I, Tigno DD, Yi ES, Platoshyn O, Thistlethwaite PA, Kriett JM, Yung G, Rubin LJ, Yuan JX. Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L740-54. PMID: 12740218.
      View in: PubMed
    63. Thistlethwaite PA, Jamieson SW. Tricuspid valvular disease in the patient with chronic pulmonary thromboembolic disease. Curr Opin Cardiol. 2003 Mar; 18(2):111-6. PMID: 12652215.
      View in: PubMed
    64. Du L, Sullivan CC, Chu D, Cho AJ, Kido M, Wolf PL, Yuan JX, Deutsch R, Jamieson SW, Thistlethwaite PA. Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med. 2003 Feb 06; 348(6):500-9. PMID: 12571257.
      View in: PubMed
    65. Thistlethwaite PA, Mo M, Madani MM, Deutsch R, Blanchard D, Kapelanski DP, Jamieson SW. Operative classification of thromboembolic disease determines outcome after pulmonary endarterectomy. J Thorac Cardiovasc Surg. 2002 Dec; 124(6):1203-11. PMID: 12447188.
      View in: PubMed
    66. Sweeney M, McDaniel SS, Platoshyn O, Zhang S, Yu Y, Lapp BR, Zhao Y, Thistlethwaite PA, Yuan JX. Role of capacitative Ca2+ entry in bronchial contraction and remodeling. J Appl Physiol (1985). 2002 Apr; 92(4):1594-602. PMID: 11896026.
      View in: PubMed
    67. Tripathy U, Yung GL, Kriett JM, Thistlethwaite PA, Kapelanski DP, Jamieson SW. Donor transfer of pulmonary coccidioidomycosis in lung transplantation. Ann Thorac Surg. 2002 Jan; 73(1):306-8. PMID: 11834038.
      View in: PubMed
    68. Thistlethwaite PA, Lee SH, Du LL, Wolf PL, Sullivan C, Pradhan S, Deutsch R, Jamieson SW. Human angiopoietin gene expression is a marker for severity of pulmonary hypertension in patients undergoing pulmonary thromboendarterectomy. J Thorac Cardiovasc Surg. 2001 Jul; 122(1):65-73. PMID: 11436038.
      View in: PubMed
    69. Thistlethwaite PA, Auger WR, Madani MM, Pradhan S, Kapelanski DP, Jamieson SW. Pulmonary thromboendarterectomy combined with other cardiac operations: indications, surgical approach, and outcome. Ann Thorac Surg. 2001 Jul; 72(1):13-7; discussion 17-9. PMID: 11465167.
      View in: PubMed
    70. Thistlethwaite PA, Kriett JM, Madani MM, Jamieson SW. Acquired aortopulmonary fistula in acute dissection. J Thorac Cardiovasc Surg. 2001 Jun; 121(6):1213-5. PMID: 11385397.
      View in: PubMed
    71. Thistlethwaite PA, Madani MM, Kriett JM, Milhoan K, Jamieson SW. Surgical management of congenital obstruction of the left main coronary artery with supravalvular aortic stenosis. J Thorac Cardiovasc Surg. 2000 Dec; 120(6):1040-6. PMID: 11088024.
      View in: PubMed
    72. Thistlethwaite PA, Tarazi RY, Giordano FJ, Jamieson SW. Surgical management of spontaneous left main coronary artery dissection. Ann Thorac Surg. 1998 Jul; 66(1):258-60. PMID: 9692481.
      View in: PubMed