-
Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2405746121.
Ganguly S, Rosenthal SB, Ishizuka K, Troutman TD, Rohm TV, Khader N, Aleman-Muench G, Sano Y, Archilei S, Soroosh P, Olefsky JM, Feldstein AE, Kisseleva T, Loomba R, Glass CK, Brenner DA, Dhar D. PMID: 39172787; PMCID: PMC11363294.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis among community-dwelling overweight and obese individuals in the USA. Gut. 2024 Aug 07.
Yang AH, Tincopa MA, Tavaglione F, Ajmera VH, Richards LM, Amangurbanova M, Butcher C, Hernandez C, Madamba E, Singh S, Bettencourt R, Schnabl B, Sirlin CB, Loomba R. PMID: 39117370.
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PubMed Mentions: Fields:
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Liver stiffness progression in biopsy-proven metabolic dysfunction-associated steatotic disease among people with diabetes versus people without diabetes: A prospective multicenter study. Hepatology. 2024 Jul 19.
Huang DQ, Wilson LA, Behling C, Amangurbanova M, Kleiner DE, Kowdley KV, Dasarathy S, Terrault NA, Diehl AM, Chalasani N, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J, Loomba R, NASH Clinical Research Network. PMID: 39028908.
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PubMed Mentions: Fields:
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Disparities for Hispanic Adults With Metabolic Dysfunction-associated Steatotic Liver Disease in the United States: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2024 Jul 16.
Tesfai K, Pace J, El-Newihi N, Martinez ME, Tincopa M, Loomba R. PMID: 39025254.
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PubMed Mentions: Fields:
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MASH Resolution Index: development and validation of a non-invasive score to detect histological resolution of MASH. Gut. 2024 07 11; 73(8):1343-1349.
Loomba R, Amangurbanova M, Bettencourt R, Madamba E, Siddiqi H, Richards L, Behling C, Sirlin CB, Gottwald MD, Feng S, Margalit M, Huang DQ. PMID: 38418210.
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PubMed Mentions: Fields:
Translation:
Humans
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Noninvasive Tests to Assess Fibrosis and Disease Severity in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic-Dysfunction-Associated Steatohepatitis. Semin Liver Dis. 2024 Jul 09.
Tincopa MA, Loomba R. PMID: 38981691.
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PubMed Mentions: Fields:
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Repeatability of vibration-controlled transient elastography versus magnetic resonance elastography in patients with cirrhosis: A prospective study. Aliment Pharmacol Ther. 2024 Aug; 60(4):484-491.
Siddiqi H, Huang DQ, Mittal N, Nourredin N, Bettencourt R, Madamba E, Amangurbanova M, Hernandez C, Sirlin C, Yin M, Loomba R. PMID: 38863232.
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PubMed Mentions: Fields:
Translation:
Humans
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Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis. N Engl J Med. 2024 Jul 25; 391(4):299-310.
Loomba R, Hartman ML, Lawitz EJ, Vuppalanchi R, Boursier J, Bugianesi E, Yoneda M, Behling C, Cummings OW, Tang Y, Brouwers B, Robins DA, Nikooie A, Bunck MC, Haupt A, Sanyal AJ, SYNERGY-NASH Investigators. PMID: 38856224.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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The impact of genetic risk on the prevalence of advanced fibrosis and cirrhosis in prospectively assessed patients with type 2 diabetes. Aliment Pharmacol Ther. 2024 08; 60(3):369-377.
Bridi L, Agrawal S, Tesfai K, Madamba E, Bettencourt R, Richards LM, Khera AV, Loomba R, Ajmera V. PMID: 38825972; PMCID: PMC11236495.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Monitoring disease progression in metabolic dysfunction-associated steatotic liver disease. Aliment Pharmacol Ther. 2024 06; 59 Suppl 1:S41-S51.
Noureddin N, Copur-Dahi N, Loomba R. PMID: 38813822; PMCID: PMC11141723.
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PubMed Mentions: Fields:
Translation:
Humans
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Integrating genetic and socioeconomic data to predict the progression of nonalcoholic fatty liver disease. Am J Biol Anthropol. 2024 08; 184(4):e24979.
Rieman-Klingler MC, Jung J, Tesfai K, Loomba R, Non AL. PMID: 38778456.
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PubMed Mentions: Fields:
Translation:
Humans
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Emerging Combination of Saroglitazar and Vitamin E for the Treatment of NAFLD and NASH. J Clin Exp Hepatol. 2024 Sep-Oct; 14(5):101449.
Tavaglione F, Loomba R. PMID: 38881684; PMCID: PMC11170343.
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PubMed Mentions:
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Potential Therapeutic Targets in Obesity, Sleep Apnea, Diabetes, and Fatty Liver Disease. J Clin Med. 2024 Apr 12; 13(8).
Gu C, Bernstein N, Mittal N, Kurnool S, Schwartz H, Loomba R, Malhotra A. PMID: 38673503; PMCID: PMC11050527.
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PubMed Mentions:
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New and emerging treatments for metabolic dysfunction-associated steatohepatitis. Cell Metab. 2024 May 07; 36(5):912-926.
Tincopa MA, Anstee QM, Loomba R. PMID: 38608696.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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A prospective study on the prevalence of at-risk MASH in patients with type 2 diabetes mellitus in the United States. Aliment Pharmacol Ther. 2024 06; 59(12):1571-1578.
Mittal N, Siddiqi H, Madamba E, Richards L, Bettencourt R, Ajmera V, Loomba R. PMID: 38586922.
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PubMed Mentions: Fields:
Translation:
Humans
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Natural history of clinical outcomes and hepatic decompensation in metabolic dysfunction-associated steatotic liver disease. Aliment Pharmacol Ther. 2024 06; 59(12):1521-1526.
Noureddin N, Huang DQ, Bettencourt R, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Gidener T, Allen AM, Ajmera V, Loomba R. PMID: 38571305.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research. Nat Metab. 2024 Apr; 6(4):600-602.
Hsu CL, Loomba R. PMID: 38383845; PMCID: PMC11262457.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease. Aliment Pharmacol Ther. 2024 05; 59(10):1183-1195.
Loomba R, Clark G, Teckman J, Ajmera V, Behling C, Brantly M, Brenner D, D'Armiento J, Fried MW, Iyer JS, Mandorfer M, Rockey DC, Tincopa M, Vuppalanchi R, Younossi Z, Krag A, Turner AM, Strnad P. PMID: 38516814.
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PubMed Mentions: Fields:
Translation:
Humans
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A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 02 08; 390(6):497-509.
Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericàs JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V, MAESTRO-NASH Investigators. PMID: 38324483.
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PubMed Mentions:
64 Fields:
Translation:
HumansCTClinical Trials
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Reply. Clin Gastroenterol Hepatol. 2024 Feb 02.
Loomba R, Zamani M. PMID: 38311149.
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PubMed Mentions: Fields:
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Implications of the new nomenclature of steatotic liver disease and definition of metabolic dysfunction-associated steatotic liver disease. Aliment Pharmacol Ther. 2024 01; 59(2):150-156.
Loomba R, Wong VW. PMID: 38153279; PMCID: PMC10807722.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Letter: Are we forgetting the importance of steatosis in steatotic liver disease? Authors' reply. Aliment Pharmacol Ther. 2024 01; 59(2):297-298.
Kuo SZ, Loomba R. PMID: 38153275.
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PubMed Mentions: Fields:
Translation:
Humans
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Diagnosis and Monitoring of Nonalcoholic Steatohepatitis: Current State and Future Directions. Radiology. 2024 Jan; 310(1):e222695.
Kadi D, Loomba R, Bashir MR. PMID: 38226882.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Randomized Trial of Pegozafermin in NASH. Reply. N Engl J Med. 2023 Dec 07; 389(23):2210.
Loomba R, Mansbach H, Margalit M. PMID: 38055266.
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PubMed Mentions: Fields:
Translation:
Humans
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Low liver fat in non-alcoholic steatohepatitis-related significant fibrosis and cirrhosis is associated with hepatocellular carcinoma, decompensation and mortality. Aliment Pharmacol Ther. 2024 01; 59(1):80-88.
Lee SW, Huang DQ, Bettencourt R, Ajmera V, Tincopa M, Noureddin N, Amangurbanova M, Siddiqi H, Madamba E, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Yoneda M, Idilman R, Gumussoy M, Oz DK, Erden A, Loomba R. PMID: 37968251; PMCID: PMC10807727.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Editorial: Can liver fat quantification stratify cardiovascular risk in type 2 diabetes? Authors' reply. Aliment Pharmacol Ther. 2023 11; 58(10):1109-1110.
Kuo SZ, Loomba R. PMID: 37885163.
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Translation:
Humans
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Validation of AGA clinical care pathway and AASLD practice guidance for nonalcoholic fatty liver disease in a prospective cohort of patients with type 2 diabetes. Hepatology. 2024 May 01; 79(5):1098-1106.
Ajmera V, Tesfai K, Sandoval E, Lopez S, Cervantes V, Madamba E, Bettencourt R, Manousou P, Richards L, Loomba R. PMID: 37862551; PMCID: PMC11023802.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Repeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE Consortium. Radiology. 2023 10; 309(1):e231092.
Fowler KJ, Venkatesh SK, Obuchowski N, Middleton MS, Chen J, Pepin K, Magnuson J, Brown KJ, Batakis D, Henderson WC, Shankar SS, Kamphaus TN, Pasek A, Calle RA, Sanyal AJ, Loomba R, Ehman R, Samir AE, Sirlin CB, Sherlock SP. PMID: 37815451; PMCID: PMC10625902.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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MEFIB-Index and MAST-Score in the assessment of hepatic decompensation in metabolic dysfunction-associated steatosis liver disease-Individual participant data meta-analyses. Aliment Pharmacol Ther. 2023 11; 58(9):856-865.
Noureddin N, Ajmera V, Bergstrom J, Bettencourt R, Huang DQ, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Loomba R. PMID: 37694993; PMCID: PMC10901230.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Adv Ther. 2023 11; 40(11):4805-4816.
Huang DQ, Ajmera V, Tomaszewski C, LaFree A, Bettencourt R, Thompson WK, Smith DM, Malhotra A, Mehta RL, Tolia V, Yin J, Insel PA, Leachman S, Jung J, Collier S, Richards L, Woods K, Amangurbanova M, Bhatt A, Zhang X, Penciu OM, Zarich S, Retta T, Harkins MS, Teixeira JP, Chinnock B, Utay NS, Lake JE, Loomba R. PMID: 37615850; PMCID: PMC10709987.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Editorial: Will MRI-PDFF become the new standard for steatosis assessment in NAFLD? Authors' reply. Aliment Pharmacol Ther. 2023 08; 58(3):366-367.
Huang DQ, Loomba R. PMID: 37452591.
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PubMed Mentions: Fields:
Translation:
Humans
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Semaglutide in NASH-related cirrhosis: still a long way to go? - Authors' reply. Lancet Gastroenterol Hepatol. 2023 Aug; 8(8):694-695.
Loomba R, Newsome PN. PMID: 37453429.
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PubMed Mentions: Fields:
Translation:
Humans
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Reply to: "Non-invasive testing for advanced fibrosis in patients with diabetes with fatty liver disease needs further evaluation of cut-off values". J Hepatol. 2023 Nov; 79(5):e192-e193.
Ajmera V, Loomba R. PMID: 37517453.
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PubMed Mentions: Fields:
-
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data meta-analysis. Lancet Gastroenterol Hepatol. 2023 09; 8(9):829-836.
Huang DQ, Noureddin N, Ajmera V, Amangurbanova M, Bettencourt R, Truong E, Gidener T, Siddiqi H, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Yoneda M, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Allen AM, Noureddin M, Loomba R. PMID: 37419133; PMCID: PMC10812844.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
Development and Validation of the Nonalcoholic Fatty Liver Disease Familial Risk Score to Detect Advanced Fibrosis: A Prospective, Multicenter Study. Clin Gastroenterol Hepatol. 2024 01; 22(1):81-90.e4.
Huang DQ, Ahlholm N, Luukkonen PK, Porthan K, Amangurbanova M, Madamba E, Bettencourt R, Siddiqi H, Cervantes V, Hernandez C, Lopez SJ, Richards L, Nemes K, Isoniemi H, Yki-Järvinen H, Loomba R. PMID: 37406954; PMCID: PMC11160482.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH. N Engl J Med. 2023 Sep 14; 389(11):998-1008.
Loomba R, Sanyal AJ, Kowdley KV, Bhatt DL, Alkhouri N, Frias JP, Bedossa P, Harrison SA, Lazas D, Barish R, Gottwald MD, Feng S, Agollah GD, Hartsfield CL, Mansbach H, Margalit M, Abdelmalek MF. PMID: 37356033; PMCID: PMC10718287.
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PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
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Clinical and histologic factors associated with discordance between steatosis grade derived from histology vs. MRI-PDFF in NAFLD. Aliment Pharmacol Ther. 2023 07; 58(2):229-237.
Kim BK, Bernstein N, Huang DQ, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 37269117; PMCID: PMC10330628.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Magnetic resonance elastography-based prediction model for hepatic decompensation in NAFLD: A multicenter cohort study. Hepatology. 2023 Dec 01; 78(6):1858-1866.
Kim BK, Bergstrom J, Loomba R, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Truong E, Yang JD, Noureddin M, Allen AM, Loomba R, Ajmera V. PMID: 37203233; PMCID: PMC10663382.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study. Gastroenterology. 2023 08; 165(2):463-472.e5.
Huang DQ, Wilson LA, Behling C, Kleiner DE, Kowdley KV, Dasarathy S, Amangurbanova M, Terrault NA, Diehl AM, Chalasani N, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J, NASH Clinical Research Network, Loomba R. PMID: 37127100; PMCID: PMC10699569.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study. Clin Gastroenterol Hepatol. 2024 01; 22(1):102-112.e9.
Loomba R, Sanyal AJ, Nakajima A, Neuschwander-Tetri BA, Goodman ZD, Harrison SA, Lawitz EJ, Gunn N, Imajo K, Ravendhran N, Akahane T, Boone B, Yamaguchi M, Chatterjee A, Tirucherai GS, Shevell DE, Du S, Charles ED, Abdelmalek MF. PMID: 37088457.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin deficiency. Aliment Pharmacol Ther. 2023 07; 58(2):152-158.
Huang DQ, Chan KE, Tan C, Zeng RW, Koh B, Ong EYH, Ong CCH, Ong CEY, Tan DJH, Lim WH, Cho E, Tan EXX, Teng MLP, Ng CH, Nah B, Lim MC, Muthiah M, Clark VC, Loomba R. PMID: 37089038; PMCID: PMC10330074.
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PubMed Mentions: Fields:
Translation:
Humans
-
Non-invasive diagnosis and monitoring of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Lancet Gastroenterol Hepatol. 2023 07; 8(7):660-670.
Tincopa MA, Loomba R. PMID: 37060912.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Global and national prevalence of nonalcoholic fatty liver disease in adolescents: An analysis of the global burden of disease study 2019. Hepatology. 2023 10 01; 78(4):1168-1181.
Hartmann P, Zhang X, Loomba R, Schnabl B. PMID: 37021791; PMCID: PMC10521800.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Global epidemiology of cirrhosis - aetiology, trends and predictions. Nat Rev Gastroenterol Hepatol. 2023 06; 20(6):388-398.
Huang DQ, Terrault NA, Tacke F, Gluud LL, Arrese M, Bugianesi E, Loomba R. PMID: 36977794; PMCID: PMC10043867.
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PubMed Mentions:
76 Fields:
Translation:
Humans
-
Semaglutide 2·4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2023 06; 8(6):511-522.
Loomba R, Abdelmalek MF, Armstrong MJ, Jara M, Kjær MS, Krarup N, Lawitz E, Ratziu V, Sanyal AJ, Schattenberg JM, Newsome PN, NN9931-4492 investigators. PMID: 36934740; PMCID: PMC10792518.
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PubMed Mentions:
55 Fields:
Translation:
HumansCTClinical Trials
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Reply to: "Screening for NAFLD and its severity in type 2 diabetic patients: Value of magnetic resonance imaging and outstanding issues". J Hepatol. 2023 05; 78(5):e168-e169.
Ajmera V, Loomba R. PMID: 36736737; PMCID: PMC10121872.
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PubMed Mentions: Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study. Lancet Gastroenterol Hepatol. 2023 02; 8(2):120-132.
Loomba R, Lawitz EJ, Frias JP, Ortiz-Lasanta G, Johansson L, Franey BB, Morrow L, Rosenstock M, Hartsfield CL, Chen CY, Tseng L, Charlton RW, Mansbach H, Margalit M. PMID: 36521501.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes. J Hepatol. 2023 03; 78(3):471-478.
Ajmera V, Cepin S, Tesfai K, Hofflich H, Cadman K, Lopez S, Madamba E, Bettencourt R, Richards L, Behling C, Sirlin CB, Loomba R. PMID: 36410554; PMCID: PMC9975077.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
Review article: the role of HSD17B13 on global epidemiology, natural history, pathogenesis and treatment of NAFLD. Aliment Pharmacol Ther. 2023 01; 57(1):37-51.
Amangurbanova M, Huang DQ, Loomba R. PMID: 36349732; PMCID: PMC10047549.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
MRI Quantification of Placebo Effect in Nonalcoholic Steatohepatitis Clinical Trials. Radiology. 2023 03; 306(3):e220743.
Nedrud MA, Chaudhry M, Middleton MS, Moylan CA, Lerebours R, Luo S, Farjat A, Guy C, Loomba R, Abdelmalek MF, Sirlin CB, Bashir MR. PMID: 36318027; PMCID: PMC9968769.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease. J Clin Invest. 2022 11 01; 132(21).
Tamaki N, Ahlholm N, Luukkonen PK, Porthan K, Sharpton SR, Ajmera V, Kono Y, Dave S, Ahmed A, Sundaram V, Wilkinson MJ, Patton H, Gupta H, Cervantes V, Hernandez C, Lopez SJ, Loomba R, Baumgartner A, Richards L, Arkkila PE, Nemes K, Isoniemi H, Yki-Järvinen H, Loomba R. PMID: 36317632; PMCID: PMC9621132.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors. Nat Rev Gastroenterol Hepatol. 2023 01; 20(1):37-49.
Huang DQ, Mathurin P, Cortez-Pinto H, Loomba R. PMID: 36258033; PMCID: PMC9579565.
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PubMed Mentions:
74 Fields:
Translation:
Humans
-
Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirrhosis. Aliment Pharmacol Ther. 2022 11; 56(10):1475-1485.
Sharpton SR, Oh TG, Madamba E, Wang C, Yu RT, Atkins AR, Huan T, Downes M, Evans RM, Loomba R. PMID: 36164267; PMCID: PMC9746351.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis. Gut. 2023 03; 72(3):581-589.
Loomba R, Huang DQ, Sanyal AJ, Anstee QM, Trauner M, Lawitz EJ, Ding D, Ma L, Jia C, Billin A, Huss RS, Chung C, Goodman Z, Wong VW, Okanoue T, Romero-Gómez M, Abdelmalek MF, Muir A, Afdhal N, Bosch J, Harrison S, Younossi ZM, Myers RP. PMID: 36750244; PMCID: PMC9905707.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Clinical Utility of Combined MRI-PDFF and ALT Response in Predicting Histologic Response in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 09; 21(10):2682-2685.e4.
Huang DQ, Sharpton SR, Amangurbanova M, Tamaki N, Sirlin CB, Loomba R, NAFLD RESEARCH STUDY GROUP. PMID: 36075503.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Shared Mechanisms between Cardiovascular Disease and NAFLD. Semin Liver Dis. 2022 11; 42(4):455-464.
Huang DQ, Downes M, Evans RM, Witztum JL, Glass CK, Loomba R. PMID: 36008083; PMCID: PMC9828940.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Semin Liver Dis. 2022 08; 42(3):233-249.
Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. PMID: 36001995; PMCID: PMC9662188.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD. J Hepatol. 2022 12; 77(6):1482-1490.
Kim BK, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Lin T, Tu XM, Bergstrom J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 35973577.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
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Hepatocellular Carcinoma Incidence in Alcohol-Associated Cirrhosis: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2023 05; 21(5):1169-1177.
Huang DQ, Tan DJH, Ng CH, Amangurbanova M, Sutter N, Lin Tay PW, Lim WH, Yong JN, Tang A, Syn N, Muthiah MD, Tan EXX, Dave S, Tay B, Majzoub AM, Gerberi D, Kim BK, Loomba R. PMID: 35940513; PMCID: PMC10792532.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
Liver Stiffness on Magnetic Resonance Elastography and the MEFIB Index and Liver-Related Outcomes in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Individual Participants. Gastroenterology. 2022 10; 163(4):1079-1089.e5.
Ajmera V, Kim BK, Yang K, Majzoub AM, Nayfeh T, Tamaki N, Izumi N, Nakajima A, Idilman R, Gumussoy M, Oz DK, Erden A, Quach NE, Tu X, Zhang X, Noureddin M, Allen AM, Loomba R. PMID: 35788349; PMCID: PMC9509452.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency. N Engl J Med. 2022 08 11; 387(6):514-524.
Strnad P, Mandorfer M, Choudhury G, Griffiths W, Trautwein C, Loomba R, Schluep T, Chang T, Yi M, Given BD, Hamilton JC, San Martin J, Teckman JH. PMID: 35748699.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCellsCTClinical Trials
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Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer. Cell Metab. 2022 07 05; 34(7):969-977.e2.
Huang DQ, Singal AG, Kono Y, Tan DJH, El-Serag HB, Loomba R. PMID: 35793659; PMCID: PMC9762323.
View in:
PubMed Mentions:
104 Fields:
Translation:
Humans
-
Changes in the gut microbiome associated with liver stiffness improvement in nonalcoholic steatohepatitis. Therap Adv Gastroenterol. 2022; 15:17562848221098243.
Sharpton SR, Podlaha O, Chuang JC, Gindin Y, Myers RP, Loomba R. PMID: 35601801; PMCID: PMC9121469.
View in:
PubMed Mentions:
1
-
Editorial: screening for hepatocellular carcinoma in NAFLD cirrhosis-towards abbreviated MRI alternative in patients with obesity? Authors' reply. Aliment Pharmacol Ther. 2022 05; 55(9):1212-1213.
Huang DQ, Loomba R. PMID: 35429041.
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PubMed Mentions: Fields:
Translation:
Humans
-
Prognostic utility of magnetic resonance elastography and MEFIB index in predicting liver-related outcomes and mortality in individuals at risk of and with nonalcoholic fatty liver disease. Therap Adv Gastroenterol. 2022; 15:17562848221093869.
Ajmera V, Nguyen K, Tamaki N, Sharpton S, Bettencourt R, Loomba R. PMID: 35509420; PMCID: PMC9058353.
View in:
PubMed Mentions:
11
-
Noninvasive assessment of liver fibrosis and its clinical significance in nonalcoholic fatty liver disease. Hepatol Res. 2022 Jun; 52(6):497-507.
Tamaki N, Kurosaki M, Huang DQ, Loomba R. PMID: 35352460; PMCID: PMC9718363.
View in:
PubMed Mentions:
15
-
Direct Comparison of Quantitative US versus Controlled Attenuation Parameter for Liver Fat Assessment Using MRI Proton Density Fat Fraction as the Reference Standard in Patients Suspected of Having NAFLD. Radiology. 2022 07; 304(1):75-82.
Jung J, Han A, Madamba E, Bettencourt R, Loomba RR, Boehringer AS, Andre MP, Erdman JW, O'Brien WD, Fowler KJ, Sirlin CB, Loomba R. PMID: 35348378; PMCID: PMC9270678.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Eliciting Patient Preferences for Hepatocellular Carcinoma Screening: A Choice-Based Conjoint Analysis. J Am Coll Radiol. 2022 04; 19(4):502-512.
Fazeli S, Covarrubias Y, Bassirian S, Cuevas J, Fowler K, Vodkin I, Kono Y, Marks R, Loomba R, Taouli B, Sirlin C, Carlos R. PMID: 35248523.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Comparative efficacy of an optimal exam between ultrasound versus abbreviated MRI for HCC screening in NAFLD cirrhosis: A prospective study. Aliment Pharmacol Ther. 2022 04; 55(7):820-827.
Huang DQ, Fowler KJ, Liau J, Cunha GM, Louie AL, An JY, Bettencourt R, Jung J, Gitto Z, Hernandez C, Lopez SJ, Gupta H, Sirlin CB, Marks RM, Loomba R. PMID: 35229334; PMCID: PMC9762322.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Two-Step Strategy, FIB-4 Followed by Magnetic Resonance Elastography, for Detecting Advanced Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2023 02; 21(2):380-387.e3.
Tamaki N, Imajo K, Sharpton SR, Jung J, Sutter N, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Kurosaki M, Izumi N, Nakajima A, Loomba R. PMID: 35123096.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Utilizing Macrosteatotic Allografts for Nonalcoholic Steatohepatitis Recipients. Liver Transpl. 2022 04; 28(4):552-553.
Brubaker AL, Loomba R. PMID: 34806817; PMCID: PMC9683541.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Magnetic resonance elastography plus Fibrosis-4 versus FibroScan-aspartate aminotransferase in detection of candidates for pharmacological treatment of NASH-related fibrosis. Hepatology. 2022 03; 75(3):661-672.
Tamaki N, Imajo K, Sharpton S, Jung J, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 34496054; PMCID: PMC9683538.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis. Front Mol Biosci. 2021; 8:790032.
Fuji H, Miller G, Nishio T, Koyama Y, Lam K, Zhang V, Loomba R, Brenner D, Kisseleva T. PMID: 34966784; PMCID: PMC8710774.
View in:
PubMed Mentions:
5
-
Noninvasive Risk Stratification for Nonalcoholic Fatty Liver Disease Among Living Liver Donor Candidates: A Proposed Algorithm. Liver Transpl. 2022 04; 28(4):670-677.
Danis N, Weeks SR, Kim A, Baghdadi A, Ghadimi M, Kamel IR, Saberi B, Woreta T, Garonzik-Wang J, Philosophe B, Gurakar A, Loomba R. PMID: 34753223; PMCID: PMC9683539.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Comparative diagnostic performance of ultrasound shear wave elastography and magnetic resonance elastography for classifying fibrosis stage in adults with biopsy-proven nonalcoholic fatty liver disease. Eur Radiol. 2022 Apr; 32(4):2457-2469.
Zhang YN, Fowler KJ, Boehringer AS, Montes V, Schlein AN, Covarrubias Y, Wolfson T, Hong CW, Valasek MA, Andre MP, Loomba R, Sirlin CB. PMID: 34854929; PMCID: PMC8921157.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD. Nat Rev Endocrinol. 2022 01; 18(1):55-66.
Tamaki N, Ajmera V, Loomba R. PMID: 34815553; PMCID: PMC9012520.
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PubMed Mentions:
47 Fields:
Translation:
Humans
-
Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholic Steatohepatitis. Gastroenterology. 2022 03; 162(3):680-688.
Loomba R, Ratziu V, Harrison SA, NASH Clinical Trial Design International Working Group. PMID: 34822801; PMCID: PMC9683540.
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PubMed Mentions:
27 Fields:
Translation:
Humans
-
A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH. N Engl J Med. 2021 10 21; 385(17):1547-1558.
Francque SM, Bedossa P, Ratziu V, Anstee QM, Bugianesi E, Sanyal AJ, Loomba R, Harrison SA, Balabanska R, Mateva L, Lanthier N, Alkhouri N, Moreno C, Schattenberg JM, Stefanova-Petrova D, Vonghia L, Rouzier R, Guillaume M, Hodge A, Romero-Gómez M, Huot-Marchand P, Baudin M, Richard MP, Abitbol JL, Broqua P, Junien JL, Abdelmalek MF, NATIVE Study Group. PMID: 34670042.
View in:
PubMed Mentions:
150 Fields:
Translation:
HumansCTClinical Trials
-
Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease. N Engl J Med. 2021 10 21; 385(17):1559-1569.
Sanyal AJ, Van Natta ML, Clark J, Neuschwander-Tetri BA, Diehl A, Dasarathy S, Loomba R, Chalasani N, Kowdley K, Hameed B, Wilson LA, Yates KP, Belt P, Lazo M, Kleiner DE, Behling C, Tonascia J, NASH Clinical Research Network (CRN). PMID: 34670043; PMCID: PMC8881985.
View in:
PubMed Mentions:
219 Fields:
Translation:
Humans
-
Diagnostic accuracy of two-dimensional shear wave elastography and transient elastography in nonalcoholic fatty liver disease. Therap Adv Gastroenterol. 2021; 14:17562848211050436.
Sharpton SR, Tamaki N, Bettencourt R, Madamba E, Jung J, Liu A, Behling C, Valasek MA, Loomba R. PMID: 34646360; PMCID: PMC8504217.
View in:
PubMed Mentions:
9
-
TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial. Gastroenterology. 2021 11; 161(5):1475-1486.
Loomba R, Mohseni R, Lucas KJ, Gutierrez JA, Perry RG, Trotter JF, Rahimi RS, Harrison SA, Ajmera V, Wayne JD, O'Farrell M, McCulloch W, Grimmer K, Rinella M, Wai-Sun Wong V, Ratziu V, Gores GJ, Neuschwander-Tetri BA, Kemble G. PMID: 34310978.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansCellsCTClinical Trials
-
Risk Difference of Liver-Related and Cardiovascular Events by Liver Fibrosis Status in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2022 05; 20(5):1171-1173.e2.
Tamaki N, Higuchi M, Kurosaki M, Loomba R, Izumi N, MRCH Liver Study Group. PMID: 34280550; PMCID: PMC8761224.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Letter: coronary atherosclerosis in patients with significant hepatic fibrosis in non-alcoholic fatty liver disease-a realm for non-invasive testing. Authors' reply. Aliment Pharmacol Ther. 2021 07; 54(2):216.
Park JG, Jung J, Loomba R. PMID: 34170539.
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PubMed Mentions: Fields:
Translation:
Humans
-
Optimal Threshold of Controlled Attenuation Parameter for Detection of HIV-Associated NAFLD With Magnetic Resonance Imaging as the Reference Standard. Clin Infect Dis. 2021 06 15; 72(12):2124-2131.
Ajmera VH, Cachay ER, Ramers CB, Bassirian S, Singh S, Bettencourt R, Richards L, Hamilton G, Middleton M, Fowler K, Sirlin C, Loomba R. PMID: 32975278; PMCID: PMC8204791.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver Diseases. Mayo Clin Proc. 2021 10; 96(10):2639-2650.
Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. PMID: 34120754; PMCID: PMC8492496.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States. Hepatology. 2021 09; 74(3):1509-1522.
Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. PMID: 33772833.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Editorial: liver stiffness by magnetic resonance elastography and cardiovascular risk in non-alcoholic fatty liver disease-simply associated or more complicated? Authors' reply. Aliment Pharmacol Ther. 2021 06; 53(11):1230-1231.
Park JG, Jung J, Loomba R. PMID: 33961702.
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PubMed Mentions: Fields:
Translation:
Humans
-
Mechanisms and disease consequences of nonalcoholic fatty liver disease. Cell. 2021 05 13; 184(10):2537-2564.
Loomba R, Friedman SL, Shulman GI. PMID: 33989548.
View in:
PubMed Mentions:
464 Fields:
Translation:
Humans
-
The impact of genetic risk on liver fibrosis in non-alcoholic fatty liver disease as assessed by magnetic resonance elastography. Aliment Pharmacol Ther. 2021 07; 54(1):68-77.
Ajmera V, Liu A, Bettencourt R, Dhar D, Richards L, Loomba R. PMID: 33975381; PMCID: PMC8985656.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease. Gut. 2022 05; 71(5):983-990.
Tamaki N, Munaganuru N, Jung J, Yonan AQ, Loomba RR, Bettencourt R, Ajmera V, Valasek MA, Behling C, Sirlin CB, Loomba R. PMID: 33883248; PMCID: PMC8594562.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Emerging Metabolic and Transcriptomic Signature of PNPLA3-Associated NASH. Hepatology. 2021 04; 73(4):1248-1250.
Dhar D, Loomba R. PMID: 33544416; PMCID: PMC9683537.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascular disease in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2021 05; 53(9):1030-1037.
Park JG, Jung J, Verma KK, Kang MK, Madamba E, Lopez S, Qas Yonan A, Liu A, Bettencourt R, Sirlin C, Loomba R. PMID: 33764550; PMCID: PMC8514119.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatitis. Hepatology. 2021 03; 73(3):881-883.
Loomba R. PMID: 33179266; PMCID: PMC8221026.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19. Contemp Clin Trials. 2021 04; 103:106330.
Ajmera V, Thompson WK, Smith DM, Malhotra A, Mehta RL, Tolia V, Yin J, Sriram K, Insel PA, Collier S, Richards L, Loomba R. PMID: 33631357; PMCID: PMC7899027.
-
Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Abdom Radiol (NY). 2021 07; 46(7):3105-3116.
Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. PMID: 33609166; PMCID: PMC8983333.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Complementary role of EUS, EndoFLIP, and manometry for management of type III achalasia with peroral endoscopic myotomy in a patient with compensated cirrhosis and no varices. VideoGIE. 2021 Apr; 6(4):167-169.
Fejleh MP, Yadlapati R, Mendler MH, Loomba R, Kwong WT, Abbas Fehmi SM. PMID: 33898892; PMCID: PMC8058387.
View in:
PubMed Mentions:
1
-
Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH. Hepatology. 2021 02; 73(2):625-643.
Loomba R, Noureddin M, Kowdley KV, Kohli A, Sheikh A, Neff G, Bhandari BR, Gunn N, Caldwell SH, Goodman Z, Wapinski I, Resnick M, Beck AH, Ding D, Jia C, Chuang JC, Huss RS, Chung C, Subramanian GM, Myers RP, Patel K, Borg BB, Ghalib R, Kabler H, Poulos J, Younes Z, Elkhashab M, Hassanein T, Iyer R, Ruane P, Shiffman ML, Strasser S, Wong VW, Alkhouri N, for the ATLAS Investigators. PMID: 33169409.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansCTClinical Trials
-
Imaging biomarkers of NAFLD, NASH, and fibrosis. Mol Metab. 2021 08; 50:101167.
Ajmera V, Loomba R. PMID: 33460786; PMCID: PMC8324681.
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PubMed Mentions:
56 Fields:
Translation:
Humans
-
The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH. Hepatology. 2021 01; 73(1):126-143.
Loomba R, Ling L, Dinh DM, DePaoli AM, Lieu HD, Harrison SA, Sanyal AJ. PMID: 32794259; PMCID: PMC7898628.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCellsCTClinical Trials
-
Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease. Cell Metab. 2021 01 05; 33(1):21-32.
Sharpton SR, Schnabl B, Knight R, Loomba R. PMID: 33296678; PMCID: PMC8414992.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimals
-
MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NASH-related fibrosis. Gut. 2021 10; 70(10):1946-1953.
Jung J, Loomba RR, Imajo K, Madamba E, Gandhi S, Bettencourt R, Singh S, Hernandez C, Valasek MA, Behling C, Richards L, Fowler K, Sirlin CB, Nakajima A, Loomba R. PMID: 33214165; PMCID: PMC8131405.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Targeting the renin-angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challenges. Proc Natl Acad Sci U S A. 2020 11 24; 117(47):29274-29282.
Sriram K, Loomba R, Insel PA. PMID: 33203679; PMCID: PMC7703541.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
-
Comparative Effectiveness of Entecavir Versus Tenofovir for Preventing Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: A Systematic Review and Meta-Analysis. Hepatology. 2021 01; 73(1):68-78.
Dave S, Park S, Murad MH, Barnard A, Prokop L, Adams LA, Singh S, Loomba R. PMID: 32277491; PMCID: PMC8022893.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Clinical Utility of Change in Nonalcoholic Fatty Liver Disease Activity Score and Change in Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2021 12; 19(12):2673-2674.e3.
Tamaki N, Munaganuru N, Jung J, Yonan AQ, Bettencourt R, Ajmera V, Valasek MA, Behling C, Loomba R. PMID: 33157318; PMCID: PMC8438785.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
RAAS Inhibitors and Risk of Covid-19. N Engl J Med. 2020 Nov 12; 383(20):1991-1992.
Sriram K, Loomba R, Insel PA. PMID: 33108103.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
-
Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH. Hepatology. 2020 10; 72(4):1219-1229.
Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C, NASH Clinical Research Network. PMID: 31965579; PMCID: PMC8055244.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCTClinical Trials
-
Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease. Gastroenterology. 2020 11; 159(5):1839-1852.
Lang S, Demir M, Martin A, Jiang L, Zhang X, Duan Y, Gao B, Wisplinghoff H, Kasper P, Roderburg C, Tacke F, Steffen HM, Goeser T, Abraldes JG, Tu XM, Loomba R, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 32652145; PMCID: PMC8404510.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co-Metabolism in Patients With Alcoholic Hepatitis. Hepatol Commun. 2020 Aug; 4(8):1168-1182.
Gao B, Duan Y, Lang S, Barupal D, Wu TC, Valdiviez L, Roberts B, Choy YY, Shen T, Byram G, Zhang Y, Fan S, Wancewicz B, Shao Y, Vervier K, Wang Y, Zhou R, Jiang L, Nath S, Loomba R, Abraldes JG, Bataller R, Tu XM, Stärkel P, Lawley TD, Fiehn O, Schnabl B. PMID: 32766476; PMCID: PMC7395072.
View in:
PubMed Mentions:
20 Fields:
-
Novel antisense inhibition of diacylglycerol O-acyltransferase 2 for treatment of non-alcoholic fatty liver disease: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial. Lancet Gastroenterol Hepatol. 2020 09; 5(9):829-838.
Loomba R, Morgan E, Watts L, Xia S, Hannan LA, Geary RS, Baker BF, Bhanot S. PMID: 32553151.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCTClinical Trials
-
Functional Microbial Responses to Alcohol Abstinence in Patients With Alcohol Use Disorder. Front Physiol. 2020; 11:370.
Gao B, Emami A, Zhou R, Lang S, Duan Y, Wang Y, Jiang L, Loomba R, Brenner DA, Stärkel P, Schnabl B. PMID: 32390870; PMCID: PMC7193112.
View in:
PubMed Mentions:
10
-
The relationship between liver triglyceride composition and proton density fat fraction as assessed by 1 H MRS. NMR Biomed. 2020 06; 33(6):e4286.
Hamilton G, Schlein AN, Wolfson T, Cunha GM, Fowler KJ, Middleton MS, Loomba R, Sirlin CB. PMID: 32128921; PMCID: PMC7211117.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Role of Noninvasive Biomarkers in the Diagnosis of Nonalcoholic Steatohepatitis With Stage 2 or 3 Fibrosis. Gastroenterol Hepatol (N Y). 2020 Mar; 16(3):139-141.
Loomba R. PMID: 34035715; PMCID: PMC8132700.
View in:
PubMed Mentions:
1
-
Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat with Radiofrequency Ultrasound Data Using One-dimensional Convolutional Neural Networks. Radiology. 2020 05; 295(2):342-350.
Han A, Byra M, Heba E, Andre MP, Erdman JW, Loomba R, Sirlin CB, O'Brien WD. PMID: 32096706; PMCID: PMC7193902.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Advances in non-invasive assessment of hepatic fibrosis. Gut. 2020 07; 69(7):1343-1352.
Loomba R, Adams LA. PMID: 32066623; PMCID: PMC7945956.
View in:
PubMed Mentions:
105 Fields:
Translation:
Humans
-
An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. Science. 2020 02 07; 367(6478):652-660.
Zhao P, Sun X, Chaggan C, Liao Z, In Wong K, He F, Singh S, Loomba R, Karin M, Witztum JL, Saltiel AR. PMID: 32029622; PMCID: PMC8012106.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansAnimalsCells
-
Assessment of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease by Using Quantitative US. Radiology. 2020 04; 295(1):106-113.
Han A, Zhang YN, Boehringer AS, Montes V, Andre MP, Erdman JW, Loomba R, Valasek MA, Sirlin CB, O'Brien WD. PMID: 32013792; PMCID: PMC7104700.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
AGA Clinical Practice Update on Screening and Surveillance for Hepatocellular Carcinoma in Patients With Nonalcoholic Fatty Liver Disease: Expert Review. Gastroenterology. 2020 05; 158(6):1822-1830.
Loomba R, Lim JK, Patton H, El-Serag HB. PMID: 32006545; PMCID: PMC8012107.
View in:
PubMed Mentions:
124 Fields:
Translation:
HumansPHPublic Health
-
Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progression in Nonalcoholic Fatty Liver Disease. Hepatology. 2020 03; 71(3):849-860.
Ajmera VH, Liu A, Singh S, Yachoa G, Ramey M, Bhargava M, Zamani A, Lopez S, Mangla N, Bettencourt R, Rizo E, Valasek M, Behling C, Richards L, Sirlin C, Loomba R. PMID: 31556124; PMCID: PMC7828573.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
-
Mass spectrometry searches using MASST. Nat Biotechnol. 2020 01; 38(1):23-26.
Wang M, Jarmusch AK, Vargas F, Aksenov AA, Gauglitz JM, Weldon K, Petras D, da Silva R, Quinn R, Melnik AV, van der Hooft JJJ, Caraballo-Rodríguez AM, Nothias LF, Aceves CM, Panitchpakdi M, Brown E, Di Ottavio F, Sikora N, Elijah EO, Labarta-Bajo L, Gentry EC, Shalapour S, Kyle KE, Puckett SP, Watrous JD, Carpenter CS, Bouslimani A, Ernst M, Swafford AD, Zúñiga EI, Balunas MJ, Klassen JL, Loomba R, Knight R, Bandeira N, Dorrestein PC. PMID: 31894142; PMCID: PMC7236533.
View in:
PubMed Mentions:
96 Fields:
-
Prospective, Same-Day, Direct Comparison of Controlled Attenuation Parameter With the M vs the XL Probe in Patients With Nonalcoholic Fatty Liver Disease, Using Magnetic Resonance Imaging-Proton Density Fat Fraction as the Standard. Clin Gastroenterol Hepatol. 2020 07; 18(8):1842-1850.e6.
Caussy C, Brissot J, Singh S, Bassirian S, Hernandez C, Bettencourt R, Rizo E, Richards L, Sirlin CB, Loomba R. PMID: 31843596; PMCID: PMC9683536.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
The 20% Rule of NASH Progression: The Natural History of Advanced Fibrosis and Cirrhosis Caused by NASH. Hepatology. 2019 12; 70(6):1885-1888.
Loomba R, Adams LA. PMID: 31520407; PMCID: PMC7504908.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
-
Gadoxetate-enhanced Abbreviated MRI for Hepatocellular Carcinoma Surveillance: Preliminary Experience. Radiol Imaging Cancer. 2019 11; 1(2):e190010.
Brunsing RL, Chen DH, Schlein A, Wolfson T, Gamst A, Mamidipalli A, Vietti Violi N, Marks RM, Taouli B, Loomba R, Kono Y, Sirlin CB. PMID: 33778680; PMCID: PMC7983773.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Letter: probiotics? Yes, but which ones? Authors' reply. Aliment Pharmacol Ther. 2019 10; 50(8):968.
Jayakumar S, Loomba R. PMID: 31591781.
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PubMed Mentions: Fields:
Translation:
Humans
-
Discovery of Half-life of Circulating Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B Infection Using Heavy Water Labeling. Clin Infect Dis. 2019 07 18; 69(3):542-545.
Loomba R, Decaris M, Li KW, Shankaran M, Mohammed H, Matthews M, Richards LM, Nguyen P, Rizo E, Andrews B, Soto R, Angel T, Suri V, Kitrinos KM, Barnes D, Czerwieniec G, Brendza K, Subramanian GM, Gaggar A, Hellerstein MK. PMID: 30590481.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):15184-15193.
Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, Evans RM, Brenner DA, Saltiel AR, Beutler B, Schnabl B. PMID: 31289229; PMCID: PMC6660779.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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MRI Assessment of Treatment Response in HIV-associated NAFLD: A Randomized Trial of a Stearoyl-Coenzyme-A-Desaturase-1 Inhibitor (ARRIVE Trial). Hepatology. 2019 11; 70(5):1531-1545.
Ajmera VH, Cachay E, Ramers C, Vodkin I, Bassirian S, Singh S, Mangla N, Bettencourt R, Aldous JL, Park D, Lee D, Blanchard J, Mamidipalli A, Boehringer A, Aslam S, Leinhard OD, Richards L, Sirlin C, Loomba R. PMID: 31013363; PMCID: PMC7164416.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Review article: emerging role of the gut microbiome in the progression of nonalcoholic fatty liver disease and potential therapeutic implications. Aliment Pharmacol Ther. 2019 07; 50(2):144-158.
Jayakumar S, Loomba R. PMID: 31149745; PMCID: PMC6771496.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and Is Associated With Liver Fibrosis Assessed by Magnetic Resonance Elastography. Hepatology. 2019 07; 70(1):127-141.
Caussy C, Bhargava M, Villesen IF, Gudmann NS, Leeming DJ, Karsdal MA, Faulkner C, Bao D, Liu A, Lo MT, Bettencourt R, Bassirian S, Richards L, Brenner DA, Chen CH, Sirlin CB, Loomba R. PMID: 30859582; PMCID: PMC6984974.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Reply. Clin Gastroenterol Hepatol. 2019 09; 17(10):2140.
Caussy C, Loomba R. PMID: 31002872.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With Fatty Liver Disease. Clin Gastroenterol Hepatol. 2020 03; 18(3):741-743.
Mills PJ, Caussy C, Loomba R. PMID: 30954713; PMCID: PMC6776714.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. Nat Commun. 2019 03 29; 10(1):1406.
Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, Loomba R. PMID: 30926798; PMCID: PMC6440960.
View in:
PubMed Mentions:
141 Fields:
Translation:
HumansCells
-
Automated CT and MRI Liver Segmentation and Biometry Using a Generalized Convolutional Neural Network. Radiol Artif Intell. 2019 Mar; 1(2).
Wang K, Mamidipalli A, Retson T, Bahrami N, Hasenstab K, Blansit K, Bass E, Delgado T, Cunha G, Middleton MS, Loomba R, Neuschwander-Tetri BA, Sirlin CB, Hsiao A, members of the NASH Clinical Research Network. PMID: 32582883; PMCID: PMC7314107.
View in:
PubMed Mentions:
46 Fields:
-
Intestinal iNKT cells migrate to liver and contribute to hepatocyte apoptosis during alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol. 2019 05 01; 316(5):G585-G597.
Lee KC, Chen P, Maricic I, Inamine T, Hu J, Gong S, Sun JC, Dasgupta S, Lin HC, Lin YT, Loomba R, Stärkel P, Kumar V, Schnabl B. PMID: 30817180; PMCID: PMC6580241.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Longitudinal evolution of CT and MRI LI-RADS v2014 category 1, 2, 3, and 4 observations. Eur Radiol. 2019 Sep; 29(9):5073-5081.
Hong CW, Park CC, Mamidipalli A, Hooker JC, Fazeli Dehkordy S, Igarashi S, Alhumayed M, Kono Y, Loomba R, Wolfson T, Gamst A, Murphy P, Sirlin CB. PMID: 30809719; PMCID: PMC7495398.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Inter-reader agreement of magnetic resonance imaging proton density fat fraction and its longitudinal change in a clinical trial of adults with nonalcoholic steatohepatitis. Abdom Radiol (NY). 2019 02; 44(2):482-492.
Hooker JC, Hamilton G, Park CC, Liao S, Wolfson T, Dehkordy SF, Hong CW, Mamidipalli A, Gamst A, Loomba R, Sirlin CB. PMID: 30128694; PMCID: PMC6382605.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Reader agreement and accuracy of ultrasound features for hepatic steatosis. Abdom Radiol (NY). 2019 01; 44(1):54-64.
Hong CW, Marsh A, Wolfson T, Paige J, Dekhordy SF, Schlein AN, Housman E, Deiranieh LH, Li CQ, Wasnik AP, Jang HJ, Dietrich CF, Piscaglia F, Casola G, O'Boyle M, Richman KM, Valasek MA, Andre M, Loomba R, Sirlin CB. PMID: 29951900; PMCID: PMC6310678.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Aliment Pharmacol Ther. 2019 01; 49(2):183-193.
Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R. PMID: 30506692; PMCID: PMC6319963.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Publisher Correction: The gut-liver axis and the intersection with the microbiome. Nat Rev Gastroenterol Hepatol. 2018 12; 15(12):785.
Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. PMID: 29785003; PMCID: PMC7133393.
View in:
PubMed Mentions:
11 Fields:
-
Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2019 08; 17(9):1867-1876.e3.
Loomba R, Jain A, Diehl AM, Guy CD, Portenier D, Sudan R, Singh S, Faulkner C, Richards L, Hester KD, Okada L, Li XJ, Mimms L, Abdelmalek MF. PMID: 30448594.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031.
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. PMID: 30327559; PMCID: PMC6245668.
View in:
PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
-
Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis. J Immunol. 2018 11 15; 201(10):3017-3035.
Maricic I, Marrero I, Eguchi A, Nakamura R, Johnson CD, Dasgupta S, Hernandez CD, Nguyen PS, Swafford AD, Knight R, Feldstein AE, Loomba R, Kumar V. PMID: 30322964; PMCID: PMC6219905.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. J Hepatol. 2019 01; 70(1):133-141.
Jayakumar S, Middleton MS, Lawitz EJ, Mantry PS, Caldwell SH, Arnold H, Mae Diehl A, Ghalib R, Elkhashab M, Abdelmalek MF, Kowdley KV, Stephen Djedjos C, Xu R, Han L, Mani Subramanian G, Myers RP, Goodman ZD, Afdhal NH, Charlton MR, Sirlin CB, Loomba R. PMID: 30291868.
View in:
PubMed Mentions:
92 Fields:
Translation:
HumansCTClinical Trials
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Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians. Clin Gastroenterol Hepatol. 2019 01; 17(2):218-230.
Allaband C, McDonald D, Vázquez-Baeza Y, Minich JJ, Tripathi A, Brenner DA, Loomba R, Smarr L, Sandborn WJ, Schnabl B, Dorrestein P, Zarrinpar A, Knight R. PMID: 30240894; PMCID: PMC6391518.
View in:
PubMed Mentions:
112 Fields:
Translation:
Humans
-
Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis. Gastroenterology. 2019 01; 156(1):88-95.e5.
Loomba R, Sanyal AJ, Kowdley KV, Terrault N, Chalasani NP, Abdelmalek MF, McCullough AJ, Shringarpure R, Ferguson B, Lee L, Chen J, Liberman A, Shapiro D, Neuschwander-Tetri BA. PMID: 30222962; PMCID: PMC6696948.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell. 2018 09 20; 175(1):133-145.e15.
Kim JY, Garcia-Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, Kaufman RJ, Saltiel AR, Karin M. PMID: 30220454; PMCID: PMC6159928.
View in:
PubMed Mentions:
133 Fields:
Translation:
HumansAnimalsCells
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Complex Network of NKT Cell Subsets Controls Immune Homeostasis in Liver and Gut. Front Immunol. 2018; 9:2082.
Marrero I, Maricic I, Feldstein AE, Loomba R, Schnabl B, Rivera-Nieves J, Eckmann L, Kumar V. PMID: 30254647; PMCID: PMC6141878.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2018 09; 561(7721):E1.
Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29973714; PMCID: PMC7871211.
View in:
PubMed Mentions:
2 Fields:
-
Refining Sample-Size Estimations Based Upon Placebo Response in Trials of Agents for Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2019 03; 17(4):607-609.
Ajmera V, Loomba R. PMID: 30153521.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Noninvasive, Quantitative Assessment of Liver Fat by MRI-PDFF as an Endpoint in NASH Trials. Hepatology. 2018 08; 68(2):763-772.
Caussy C, Reeder SB, Sirlin CB, Loomba R. PMID: 29356032; PMCID: PMC6054824.
View in:
PubMed Mentions:
152 Fields:
Translation:
Humans
-
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 11; 155(5):1463-1473.e6.
Loomba R, Kayali Z, Noureddin M, Ruane P, Lawitz EJ, Bennett M, Wang L, Harting E, Tarrant JM, McColgan BJ, Chung C, Ray AS, Subramanian GM, Myers RP, Middleton MS, Lai M, Charlton M, Harrison SA. PMID: 30059671; PMCID: PMC6318218.
View in:
PubMed Mentions:
120 Fields:
Translation:
HumansCTClinical Trials
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The gut-liver axis and the intersection with the microbiome. Nat Rev Gastroenterol Hepatol. 2018 07; 15(7):397-411.
Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. PMID: 29748586; PMCID: PMC6319369.
View in:
PubMed Mentions:
523 Fields:
Translation:
Humans
-
Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants. Clin Gastroenterol Hepatol. 2019 03; 17(4):630-637.e8.
Hsu C, Caussy C, Imajo K, Chen J, Singh S, Kaulback K, Le MD, Hooker J, Tu X, Bettencourt R, Yin M, Sirlin CB, Ehman RL, Nakajima A, Loomba R. PMID: 29908362; PMCID: PMC6294709.
View in:
PubMed Mentions:
142 Fields:
Translation:
Humans
-
Assessment of a high-SNR chemical-shift-encoded MRI with complex reconstruction for proton density fat fraction (PDFF) estimation overall and in the low-fat range. J Magn Reson Imaging. 2019 01; 49(1):229-238.
Park CC, Hooker C, Hooker JC, Bass E, Haufe W, Schlein A, Covarrubias Y, Heba E, Bydder M, Wolfson T, Gamst A, Loomba R, Schwimmer J, Hernando D, Reeder SB, Middleton M, Sirlin CB, Hamilton G. PMID: 29707848; PMCID: PMC6205914.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice. Hepatology. 2018 06; 67(6):2150-2166.
Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, Rossi SJ, DePaoli AM, Downes M, Evans RM, Brenner DA, Schnabl B. PMID: 29159825; PMCID: PMC5962369.
View in:
PubMed Mentions:
119 Fields:
Translation:
Animals
-
Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 08; 155(2):307-310.e2.
Ajmera V, Park CC, Caussy C, Singh S, Hernandez C, Bettencourt R, Hooker J, Sy E, Behling C, Xu R, Middleton MS, Valasek MA, Faulkner C, Rizo E, Richards L, Sirlin CB, Loomba R. PMID: 29660324; PMCID: PMC6090543.
View in:
PubMed Mentions:
66 Fields:
Translation:
Humans
-
Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis. J Hepatol. 2018 08; 69(2):396-405.
Brandl K, Hartmann P, Jih LJ, Pizzo DP, Argemi J, Ventura-Cots M, Coulter S, Liddle C, Ling L, Rossi SJ, DePaoli AM, Loomba R, Mehal WZ, Fouts DE, Lucey MR, Bosques-Padilla F, Mathurin P, Louvet A, Garcia-Tsao G, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross D, Stärkel P, Ho SB, Bataller R, Schnabl B. PMID: 29654817; PMCID: PMC6054564.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansCells
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Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis. Clin Gastroenterol Hepatol. 2018 09; 16(9):1511-1520.e5.
Ajmera V, Belt P, Wilson LA, Gill RM, Loomba R, Kleiner DE, Neuschwander-Tetri BA, Terrault N, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 29378307; PMCID: PMC6098737.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Can Elastography Differentiate Isolated Fatty Liver from Nonalcoholic Steatohepatitis? Semin Liver Dis. 2018 02; 38(1):14-20.
Ajmera V, Loomba R. PMID: 29471562.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
Optimal threshold of controlled attenuation parameter with MRI-PDFF as the gold standard for the detection of hepatic steatosis. Hepatology. 2018 04; 67(4):1348-1359.
Caussy C, Alquiraish MH, Nguyen P, Hernandez C, Cepin S, Fortney LE, Ajmera V, Bettencourt R, Collier S, Hooker J, Sy E, Rizo E, Richards L, Sirlin CB, Loomba R. PMID: 29108123; PMCID: PMC5867216.
View in:
PubMed Mentions:
139 Fields:
Translation:
Humans
-
DNA methylation signatures reflect aging in patients with nonalcoholic steatohepatitis. JCI Insight. 2018 01 25; 3(2).
Loomba R, Gindin Y, Jiang Z, Lawitz E, Caldwell S, Djedjos CS, Xu R, Chung C, Myers RP, Subramanian GM, Goodman Z, Charlton M, Afdhal NH, Diehl AM. PMID: 29367468; PMCID: PMC5821203.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. Clin Gastroenterol Hepatol. 2018 12; 16(12):1974-1982.e7.
Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Ehman RL, Loomba R. PMID: 29104128; PMCID: PMC6050151.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial. Hepatology. 2018 02; 67(2):549-559.
Loomba R, Lawitz E, Mantry PS, Jayakumar S, Caldwell SH, Arnold H, Diehl AM, Djedjos CS, Han L, Myers RP, Subramanian GM, McHutchison JG, Goodman ZD, Afdhal NH, Charlton MR, GS-US-384-1497 Investigators. PMID: 28892558; PMCID: PMC5814892.
View in:
PubMed Mentions:
235 Fields:
Translation:
HumansCTClinical Trials
-
Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nat Commun. 2017 12 12; 8(1):2137.
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, Du X, Sørensen HT, Vilstrup H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. PMID: 29233961; PMCID: PMC5727102.
View in:
PubMed Mentions:
9 Fields:
-
Do Zones of Hepatic Steatosis Associate With Subtypes and Progression of Nonalcoholic Fatty Liver Disease in Children? Clin Gastroenterol Hepatol. 2018 03; 16(3):341-342.
Ajmera V, Loomba R. PMID: 29199148; PMCID: PMC5881903.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Role of imaging-based biomarkers in NAFLD: Recent advances in clinical application and future research directions. J Hepatol. 2018 02; 68(2):296-304.
Loomba R. PMID: 29203392; PMCID: PMC5810949.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Role of two-dimensional shear wave elastography in the assessment of chronic liver diseases. Hepatology. 2018 01; 67(1):13-15.
Singh S, Loomba R. PMID: 28777887; PMCID: PMC5807079.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 2017 11 16; 551(7680):340-345.
Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. PMID: 29144460; PMCID: PMC5884449.
View in:
PubMed Mentions:
249 Fields:
Translation:
HumansAnimalsCells
-
Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. Eur Radiol. 2018 Apr; 28(4):1345-1355.
Brouha SS, Nguyen P, Bettencourt R, Sirlin CB, Loomba R. PMID: 29058029; PMCID: PMC6310479.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nat Commun. 2017 10 16; 8(1):837.
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, Du X, Sørensen HT, Vilstrup H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. PMID: 29038503; PMCID: PMC5643518.
View in:
PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
-
Reply. Hepatology. 2017 10; 66(4):1359-1360.
Singh S, Loomba R. PMID: 28727157.
View in:
PubMed Mentions: Fields:
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Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis. Radiology. 2018 02; 286(2):486-498.
Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn JP, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB, Sirlin CB, RSNA-QIBA PDFF Biomarker Committee. PMID: 28892458; PMCID: PMC5813433.
View in:
PubMed Mentions:
128 Fields:
Translation:
Humans
-
MRI proton density fat fraction is robust across the biologically plausible range of triglyceride spectra in adults with nonalcoholic steatohepatitis. J Magn Reson Imaging. 2018 04; 47(4):995-1002.
Hong CW, Mamidipalli A, Hooker JC, Hamilton G, Wolfson T, Chen DH, Fazeli Dehkordy S, Middleton MS, Reeder SB, Loomba R, Sirlin CB. PMID: 28851124; PMCID: PMC5832550.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. J Magn Reson Imaging. 2018 04; 47(4):988-994.
Hong CW, Wolfson T, Sy EZ, Schlein AN, Hooker JC, Fazeli Dehkordy S, Hamilton G, Reeder SB, Loomba R, Sirlin CB. PMID: 28842937; PMCID: PMC5826828.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. J Clin Invest. 2017 Jun 30; 127(7):2697-2704.
Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, Hemming A, Andrews B, Salotti J, Richards L, Brenner DA, Sirlin CB, Loomba R, Familial NAFLD Cirrhosis Research Consortium. PMID: 28628033; PMCID: PMC5490764.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansCTClinical Trials
-
Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. Gastroenterology. 2017 09; 153(3):753-761.
Middleton MS, Heba ER, Hooker CA, Bashir MR, Fowler KJ, Sandrasegaran K, Brunt EM, Kleiner DE, Doo E, Van Natta ML, Lavine JE, Neuschwander-Tetri BA, Sanyal A, Loomba R, Sirlin CB, NASH Clinical Research Network. PMID: 28624576; PMCID: PMC5695870.
View in:
PubMed Mentions:
117 Fields:
Translation:
HumansCTClinical Trials
-
Increased Risk of Death, in the Hospital and Outside the Intensive Care Unit, for Patients With Cirrhosis After Cardiac Arrest. Clin Gastroenterol Hepatol. 2017 11; 15(11):1808-1810.
Reinders ME, Wardi G, Bettencourt R, Bouland D, Bazick J, Mendler M, Vodkin I, Kalmaz D, Savides T, Brenner D, Sell RE, Loomba R. PMID: 28602970; PMCID: PMC5723019.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Magnitude and Kinetics of Decrease in Liver Stiffness After Antiviral Therapy in Patients With Chronic Hepatitis C: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):27-38.e4.
Singh S, Facciorusso A, Loomba R, Falck-Ytter YT. PMID: 28479504; PMCID: PMC5671365.
View in:
PubMed Mentions:
78 Fields:
Translation:
Humans
-
Statin Use and Risk of Cirrhosis and Related Complications in Patients With Chronic Liver Diseases: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2017 Oct; 15(10):1521-1530.e8.
Kim RG, Loomba R, Prokop LJ, Singh S. PMID: 28479502; PMCID: PMC5605397.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5.
Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. PMID: 28467925; PMCID: PMC5502730.
View in:
PubMed Mentions:
424 Fields:
Translation:
HumansCells
-
Effect of intravenous gadoxetate disodium and flip angle on hepatic proton density fat fraction estimation with six-echo, gradient-recalled-echo, magnitude-based MR imaging at 3T. Abdom Radiol (NY). 2017 04; 42(4):1189-1198.
Park CC, Hamilton G, Desai A, Zand KA, Wolfson T, Hooker JC, Costa E, Heba E, Clark L, Gamst A, Loomba R, Middleton MS, Sirlin CB. PMID: 28028556.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis. Hepatology. 2017 May; 65(5):1557-1565.
Dulai PS, Singh S, Patel J, Soni M, Prokop LJ, Younossi Z, Sebastiani G, Ekstedt M, Hagstrom H, Nasr P, Stal P, Wong VW, Kechagias S, Hultcrantz R, Loomba R. PMID: 28130788; PMCID: PMC5397356.
View in:
PubMed Mentions:
615 Fields:
Translation:
Humans
-
Quantifying Abdominal Adipose Tissue and Thigh Muscle Volume and Hepatic Proton Density Fat Fraction: Repeatability and Accuracy of an MR Imaging-based, Semiautomated Analysis Method. Radiology. 2017 05; 283(2):438-449.
Middleton MS, Haufe W, Hooker J, Borga M, Dahlqvist Leinhard O, Romu T, Tunón P, Hamilton G, Wolfson T, Gamst A, Loomba R, Sirlin CB. PMID: 28278002; PMCID: PMC5410959.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
A Pilot Comparative Study of Quantitative Ultrasound, Conventional Ultrasound, and MRI for Predicting Histology-Determined Steatosis Grade in Adult Nonalcoholic Fatty Liver Disease. AJR Am J Roentgenol. 2017 May; 208(5):W168-W177.
Paige JS, Bernstein GS, Heba E, Costa EAC, Fereirra M, Wolfson T, Gamst AC, Valasek MA, Lin GY, Han A, Erdman JW, O'Brien WD, Andre MP, Loomba R, Sirlin CB. PMID: 28267360; PMCID: PMC5512552.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
-
Hepatitis B Reactivation Associated With Immune Suppressive and Biological Modifier Therapies: Current Concepts, Management Strategies, and Future Directions. Gastroenterology. 2017 05; 152(6):1297-1309.
Loomba R, Liang TJ. PMID: 28219691; PMCID: PMC5501983.
View in:
PubMed Mentions:
229 Fields:
Translation:
HumansCellsPHPublic Health
-
Letter: comparative diagnostic accuracy of magnetic resonance elastography vs. eight clinical prediction rules for non-invasive diagnosis of advanced fibrosis in biopsy-proven NAFLD - author's reply. Aliment Pharmacol Ther. 2017 02; 45(3):479.
Loomba R. PMID: 28043090.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells. Cell Rep. 2016 12 13; 17(11):2979-2993.
Luo X, Liao R, Hanley KL, Zhu HH, Malo KN, Hernandez C, Wei X, Varki NM, Alderson N, Chu C, Li S, Fan J, Loomba R, Qiu SJ, Feng GS. PMID: 27974211; PMCID: PMC5330282.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
-
Race/ethnic and sex disparities in the non-alcoholic fatty liver disease-abdominal aortic calcification association: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2017 03; 258:89-96.
Remigio-Baker RA, Allison MA, Forbang NI, Loomba R, Anderson CAM, Budoff M, Schwimmer JB, Blumenthal RS, Ouyang P, Criqui MH. PMID: 28235711; PMCID: PMC5502083.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease. Gastroenterology. 2017 02; 152(3):598-607.e2.
Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez K, Fortney L, Hooker J, Sy E, Savides MT, Alquiraish MH, Valasek MA, Rizo E, Richards L, Brenner D, Sirlin CB, Loomba R. PMID: 27911262; PMCID: PMC5285304.
View in:
PubMed Mentions:
279 Fields:
Translation:
Humans
-
Weight Loss Decreases Magnetic Resonance Elastography Estimated Liver Stiffness in Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2017 03; 15(3):463-464.
Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner D, Sirlin CB, Loomba R. PMID: 27712981; PMCID: PMC5476292.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Editorial: non-invasive assessment of hepatic fibrosis in alpha-1 antitrypsin deficiency using magnetic resonance elastography - authors' reply. Aliment Pharmacol Ther. 2016 09; 44(6):645-6.
Kim RG, Loomba R. PMID: 27511135.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. Hepatology. 2016 11; 64(5):1547-1558.
Cui J, Chen CH, Lo MT, Schork N, Bettencourt R, Gonzalez MP, Bhatt A, Hooker J, Shaffer K, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. PMID: 27315352; PMCID: PMC5090982.
View in:
PubMed Mentions:
37 Fields:
Translation:
Humans
-
Reply. Hepatology. 2016 12; 64(6):2263.
Cui J, Loomba R. PMID: 27286884.
View in:
PubMed Mentions: Fields:
-
Association of noninvasive quantitative decline in liver fat content on MRI with histologic response in nonalcoholic steatohepatitis. Therap Adv Gastroenterol. 2016 Sep; 9(5):692-701.
Patel J, Bettencourt R, Cui J, Salotti J, Hooker J, Bhatt A, Hernandez C, Nguyen P, Aryafar H, Valasek M, Haufe W, Hooker C, Richards L, Sirlin CB, Loomba R. PMID: 27582882; PMCID: PMC4984335.
View in:
PubMed Mentions:
65
-
MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: Clinical trials to clinical practice. J Hepatol. 2016 11; 65(5):1006-1016.
Dulai PS, Sirlin CB, Loomba R. PMID: 27312947; PMCID: PMC5124376.
View in:
PubMed Mentions:
147 Fields:
Translation:
Humans
-
Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study. Aliment Pharmacol Ther. 2016 08; 44(3):287-99.
Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J, Minocha J, Valasek MA, Aryafar H, Brenner DA, Sirlin CB, Loomba R. PMID: 27279429.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial. J Hepatol. 2016 08; 65(2):369-76.
Cui J, Philo L, Nguyen P, Hofflich H, Hernandez C, Bettencourt R, Richards L, Salotti J, Bhatt A, Hooker J, Haufe W, Hooker C, Brenner DA, Sirlin CB, Loomba R. PMID: 27151177; PMCID: PMC5081213.
View in:
PubMed Mentions:
135 Fields:
Translation:
Humans
-
Novel 3D Magnetic Resonance Elastography for the Noninvasive Diagnosis of Advanced Fibrosis in NAFLD: A Prospective Study. Am J Gastroenterol. 2016 07; 111(7):986-94.
Loomba R, Cui J, Wolfson T, Haufe W, Hooker J, Szeverenyi N, Ang B, Bhatt A, Wang K, Aryafar H, Behling C, Valasek MA, Lin GY, Gamst A, Brenner DA, Yin M, Glaser KJ, Ehman RL, Sirlin CB. PMID: 27002798; PMCID: PMC5001170.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
-
Cardiovascular risk assessment in the treatment of nonalcoholic steatohepatitis: a secondary analysis of the MOZART trial. Therap Adv Gastroenterol. 2016 Mar; 9(2):152-61.
Lin SC, Ang B, Hernandez C, Bettencourt R, Jain R, Salotti J, Richards L, Kono Y, Bhatt A, Aryafar H, Lin GY, Valasek MA, Sirlin CB, Brouha S, Loomba R. PMID: 26929777; PMCID: PMC4749859.
View in:
PubMed Mentions:
5
-
Reply. Hepatology. 2016 08; 64(2):694.
Singh S, Khera R, Murad MH, Loomba R. PMID: 26690078.
View in:
PubMed Mentions:
1 Fields:
-
Targeting Dysbiosis for the Treatment of Liver Disease. Semin Liver Dis. 2016 Feb; 36(1):37-47.
Anand G, Zarrinpar A, Loomba R. PMID: 26870931; PMCID: PMC6658186.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
-
Association of Nonalcoholic Fatty Liver Disease With Visceral Adiposity but Not Coronary Artery Calcification in the Elderly. Clin Gastroenterol Hepatol. 2016 09; 14(9):1337-1344.e3.
Jacobs K, Brouha S, Bettencourt R, Barrett-Connor E, Sirlin C, Loomba R. PMID: 26820400.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Editorial: obesity in chronic liver diseases - increased infections. Aliment Pharmacol Ther. 2016 Jan; 43(2):311-2.
Singh S, Loomba R. PMID: 26741982.
View in:
PubMed Mentions: Fields:
-
Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. Nucl Med Biol. 2016 Feb; 43(2):179-87.
Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. PMID: 26872443.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Intra- and inter-examination repeatability of magnetic resonance spectroscopy, magnitude-based MRI, and complex-based MRI for estimation of hepatic proton density fat fraction in overweight and obese children and adults. Abdom Imaging. 2015 Oct; 40(8):3070-7.
Tyagi A, Yeganeh O, Levin Y, Hooker JC, Hamilton GC, Wolfson T, Gamst A, Zand AK, Heba E, Loomba R, Schwimmer J, Middleton MS, Sirlin CB. PMID: 26350282; PMCID: PMC4819976.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Non-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE. Aliment Pharmacol Ther. 2016 Jan; 43(1):83-95.
Doycheva I, Cui J, Nguyen P, Costa EA, Hooker J, Hofflich H, Bettencourt R, Brouha S, Sirlin CB, Loomba R. PMID: 26369383; PMCID: PMC4673036.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
-
Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. 2015 Dec; 149(7):1784-93.
Loomba R, Schork N, Chen CH, Bettencourt R, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Seki E, Nelson KE, Sirlin CB, Brenner D, Genetics of NAFLD in Twins Consortium. PMID: 26299412; PMCID: PMC4663110.
View in:
PubMed Mentions:
161 Fields:
Translation:
Humans
-
Accuracy and the effect of possible subject-based confounders of magnitude-based MRI for estimating hepatic proton density fat fraction in adults, using MR spectroscopy as reference. J Magn Reson Imaging. 2016 Feb; 43(2):398-406.
Heba ER, Desai A, Zand KA, Hamilton G, Wolfson T, Schlein AN, Gamst A, Loomba R, Sirlin CB, Middleton MS. PMID: 26201284; PMCID: PMC4819980.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
In vivo breath-hold (1) H MRS simultaneous estimation of liver proton density fat fraction, and T1 and T2 of water and fat, with a multi-TR, multi-TE sequence. J Magn Reson Imaging. 2015 Dec; 42(6):1538-43.
Hamilton G, Middleton MS, Hooker JC, Haufe WM, Forbang NI, Allison MA, Loomba R, Sirlin CB. PMID: 26114603; PMCID: PMC4691228.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
The Hierarchical Model of NAFLD: Prognostic Significance of Histologic Features in NASH. Gastroenterology. 2015 Aug; 149(2):278-81.
Loomba R, Chalasani N. PMID: 26116800.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis. Gastroenterology. 2015 Oct; 149(4):958-70.e12.
Singh S, Murad MH, Chandar AK, Bongiorno CM, Singal AK, Atkinson SR, Thursz MR, Loomba R, Shah VH. PMID: 26091937.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Serum microRNAs explain discordance of non-alcoholic fatty liver disease in monozygotic and dizygotic twins: a prospective study. Gut. 2016 09; 65(9):1546-54.
Zarrinpar A, Gupta S, Maurya MR, Subramaniam S, Loomba R. PMID: 26002934; PMCID: PMC5089367.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
Successful combined liver/kidney transplantation from a donor with Pompe disease. Mol Genet Metab. 2015 Aug; 115(4):141-4.
Halldorson J, Kazi Z, Mekeel K, Kuo A, Hassanein T, Loomba R, Austin S, Valasek MA, Kishnani P, Hemming AW. PMID: 26031770.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 01; 309(1):G30-41.
Roh YS, Zhang B, Loomba R, Seki E. PMID: 25930080; PMCID: PMC4491507.
View in:
PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
-
Clinical Model for NASH and Advanced Fibrosis in Adult Patients With Diabetes and NAFLD: Guidelines for Referral in NAFLD. Diabetes Care. 2015 Jul; 38(7):1347-55.
Bazick J, Donithan M, Neuschwander-Tetri BA, Kleiner D, Brunt EM, Wilson L, Doo E, Lavine J, Tonascia J, Loomba R. PMID: 25887357; PMCID: PMC4477334.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
-
Comparative diagnostic accuracy of magnetic resonance elastography vs. eight clinical prediction rules for non-invasive diagnosis of advanced fibrosis in biopsy-proven non-alcoholic fatty liver disease: a prospective study. Aliment Pharmacol Ther. 2015 Jun; 41(12):1271-80.
Cui J, Ang B, Haufe W, Hernandez C, Verna EC, Sirlin CB, Loomba R. PMID: 25873207; PMCID: PMC4532628.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
-
Exercise and improvement of NAFLD: Practical recommendations. J Hepatol. 2015 Jul; 63(1):10-2.
Loomba R, Cortez-Pinto H. PMID: 25863525.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Hepatology. 2015 Apr; 61(4):1239-50.
Loomba R, Sirlin CB, Ang B, Bettencourt R, Jain R, Salotti J, Soaft L, Hooker J, Kono Y, Bhatt A, Hernandez L, Nguyen P, Noureddin M, Haufe W, Hooker C, Yin M, Ehman R, Lin GY, Valasek MA, Brenner DA, Richards L, San Diego Integrated NAFLD Research Consortium (SINC). PMID: 25482832; PMCID: PMC4407930.
View in:
PubMed Mentions:
173 Fields:
Translation:
Humans
-
Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2015 Aug; 13(8):1513-20.e1.
Arulanandan A, Ang B, Bettencourt R, Hooker J, Behling C, Lin GY, Valasek MA, Ix JH, Schnabl B, Sirlin CB, Loomba R. PMID: 25661453.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Clinical, biochemical and histological differences between HIV-associated NAFLD and primary NAFLD: a case-control study. Aliment Pharmacol Ther. 2015 Feb; 41(4):368-78.
Vodkin I, Valasek MA, Bettencourt R, Cachay E, Loomba R. PMID: 25496369.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat Using a New Quantitative Ultrasound Technique. Clin Gastroenterol Hepatol. 2015 Jul; 13(7):1337-1345.e6.
Lin SC, Heba E, Wolfson T, Ang B, Gamst A, Han A, Erdman JW, O'Brien WD, Andre MP, Sirlin CB, Loomba R. PMID: 25478922; PMCID: PMC4454635.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansAnimals
-
The TM6SF2 variants, novel genetic predictors for nonalcoholic steatohepatitis. Gastroenterology. 2015 Jan; 148(1):252-4.
Roh YS, Loomba R, Seki E. PMID: 25451657; PMCID: PMC4718074.
View in:
PubMed Mentions:
10 Fields:
-
Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis. J Lipid Res. 2015 Jan; 56(1):185-92.
Loomba R, Quehenberger O, Armando A, Dennis EA. PMID: 25404585; PMCID: PMC4274066.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
-
Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology. 2014 Dec; 60(6):1920-8.
Loomba R, Wolfson T, Ang B, Hooker J, Behling C, Peterson M, Valasek M, Lin G, Brenner D, Gamst A, Ehman R, Sirlin C. PMID: 25103310; PMCID: PMC4245360.
View in:
PubMed Mentions:
206 Fields:
Translation:
HumansCTClinical Trials
-
Rationale for conducting a randomized trial to examine the efficacy of metformin in improving survival in cirrhosis: pleiotropic effects hypothesis. Hepatology. 2014 Dec; 60(6):1818-22.
Loomba R. PMID: 25043205.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Associations between histologic features of nonalcoholic fatty liver disease (NAFLD) and quantitative diffusion-weighted MRI measurements in adults. J Magn Reson Imaging. 2015 Jun; 41(6):1629-38.
Murphy P, Hooker J, Ang B, Wolfson T, Gamst A, Bydder M, Middleton M, Peterson M, Behling C, Loomba R, Sirlin C. PMID: 25256692; PMCID: PMC4819971.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Accuracy of MR imaging-estimated proton density fat fraction for classification of dichotomized histologic steatosis grades in nonalcoholic fatty liver disease. Radiology. 2015 Feb; 274(2):416-25.
Tang A, Desai A, Hamilton G, Wolfson T, Gamst A, Lam J, Clark L, Hooker J, Chavez T, Ang BD, Middleton MS, Peterson M, Loomba R, Sirlin CB. PMID: 25247408; PMCID: PMC4314291.
View in:
PubMed Mentions:
130 Fields:
Translation:
Humans
-
Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. Gastroenterology. 2015 Jan; 148(1):203-214.e16.
Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, van Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B. PMID: 25239591; PMCID: PMC4274236.
View in:
PubMed Mentions:
157 Fields:
Translation:
AnimalsCells
-
Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2015 Mar; 13(3):561-568.e1.
Patel NS, Doycheva I, Peterson MR, Hooker J, Kisselva T, Schnabl B, Seki E, Sirlin CB, Loomba R. PMID: 25218667; PMCID: PMC4333065.
View in:
PubMed Mentions:
62 Fields:
Translation:
Humans
-
Hepatocellular carcinoma surveillance: a national survey of current practices in the USA. Dig Dis Sci. 2014 Dec; 59(12):3073-7.
Joshi K, Mendler M, Gish R, Loomba R, Kuo A, Patton H, Kono Y. PMID: 25027206.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansPHPublic Health
-
State of the art: treatment of nonalcoholic steatohepatitis. Curr Opin Gastroenterol. 2014 May; 30(3):223-37.
Pearlman M, Loomba R. PMID: 24717764.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Serum alanine aminotransferase as a biomarker of treatment response in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2014 Oct; 12(10):1731-2.
Loomba R. PMID: 24703861; PMCID: PMC4171196.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Controversies in the Diagnosis and Management of NAFLD and NASH. Gastroenterol Hepatol (N Y). 2014 Apr; 10(4):219-27.
Rinella ME, Loomba R, Caldwell SH, Kowdley K, Charlton M, Tetri B, Harrison SA. PMID: 24976805; PMCID: PMC4073533.
View in:
PubMed Mentions:
31
-
Commentary: dissecting the PNPLA3 association with liver fat and stiffness, and interaction with diet. Aliment Pharmacol Ther. 2014 Apr; 39(8):894-5.
Stinton L, Loomba R. PMID: 24635311; PMCID: PMC4119823.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Recommendations for liver biopsy evaluation in non-alcoholic fatty liver disease. Minerva Gastroenterol Dietol. 2014 Mar; 60(1):5-13.
Stinton LM, Loomba R. PMID: 24632764.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Association of serum bilirubin with aging and mortality. J Clin Exp Hepatol. 2014 Mar; 4(1):1-7.
Boland BS, Dong MH, Bettencourt R, Barrett-Connor E, Loomba R. PMID: 25328328; PMCID: PMC4017193.
View in:
PubMed Mentions:
18
-
Effect of metformin on ballooning degeneration in nonalcoholic steatohepatitis (NASH): when to use metformin in nonalcoholic fatty liver disease (NAFLD). Adv Ther. 2014 Jan; 31(1):30-43.
Doycheva I, Loomba R. PMID: 24385405.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. Hepatology. 2014 Feb; 59(2):483-95.
Yang L, Roh YS, Song J, Zhang B, Liu C, Loomba R, Seki E. PMID: 23996730; PMCID: PMC3946696.
View in:
PubMed Mentions:
127 Fields:
Translation:
AnimalsCells
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Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls. Gastroenterol Res Pract. 2013; 2013:498296.
Patel NS, Peterson MR, Lin GY, Feldstein A, Schnabl B, Bettencourt R, Seki E, Sirlin CB, Loomba R. PMID: 24348536; PMCID: PMC3855930.
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27
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Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology. 2013 Dec; 58(6):1930-40.
Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. PMID: 23696515; PMCID: PMC4819962.
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PubMed Mentions:
235 Fields:
Translation:
Humans
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Inter-examination precision of magnitude-based MRI for estimation of segmental hepatic proton density fat fraction in obese subjects. J Magn Reson Imaging. 2014 May; 39(5):1265-71.
Negrete LM, Middleton MS, Clark L, Wolfson T, Gamst AC, Lam J, Changchien C, Deyoung-Dominguez IM, Hamilton G, Loomba R, Schwimmer J, Sirlin CB. PMID: 24136736; PMCID: PMC3984359.
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26 Fields:
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Humans
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Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients. Hepatology. 2013 Nov; 58(5):1644-54.
Noureddin M, Yates KP, Vaughn IA, Neuschwander-Tetri BA, Sanyal AJ, McCullough A, Merriman R, Hameed B, Doo E, Kleiner DE, Behling C, Loomba R, NASH CRN. PMID: 23686698; PMCID: PMC3760979.
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PubMed Mentions:
66 Fields:
Translation:
Humans
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The global NAFLD epidemic. Nat Rev Gastroenterol Hepatol. 2013 11; 10(11):686-90.
Loomba R, Sanyal AJ. PMID: 24042449.
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PubMed Mentions:
809 Fields:
Translation:
HumansPHPublic Health
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Null association between abdominal muscle and calcified atherosclerosis in community-living persons without clinical cardiovascular disease: the multi-ethnic study of atherosclerosis. Metabolism. 2013 Nov; 62(11):1562-9.
Jensky NE, Allison MA, Loomba R, Carnethon MR, de Boer IH, Budoff MJ, Burke GL, Criqui MH, Ix JH. PMID: 23916063; PMCID: PMC3740763.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-echo MRI hepatic fat fraction estimation. J Magn Reson Imaging. 2014 Mar; 39(3):567-75.
Levin YS, Yokoo T, Wolfson T, Gamst AC, Collins J, Achmad EA, Hamilton G, Middleton MS, Loomba R, Sirlin CB. PMID: 23720420; PMCID: PMC3760998.
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11 Fields:
Translation:
Humans
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Synergistic effects of family history of hepatocellular carcinoma and hepatitis B virus infection on risk for incident hepatocellular carcinoma. Clin Gastroenterol Hepatol. 2013 Dec; 11(12):1636-45.e1-3.
Loomba R, Liu J, Yang HI, Lee MH, Lu SN, Wang LY, Iloeje UH, You SL, Brenner D, Chen CJ, REVEAL–HBV Study Group. PMID: 23669307; PMCID: PMC4100777.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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Commentary: non-alcoholic fatty pancreas -- toward an uncharted territory; authors' reply. Aliment Pharmacol Ther. 2013 May; 37(9):916-7.
Patel NS, Loomba R. PMID: 23551158; PMCID: PMC4135375.
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Humans
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Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7.
Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. PMID: 23596052; PMCID: PMC3732566.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Serum γ-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. J Clin Exp Hepatol. 2013 Mar 01; 3(1):4-11.
Loomba R, Doycheva I, Bettencourt R, Cohen B, Wassel CL, Brenner D, Barrett-Connor E. PMID: 23997501; PMCID: PMC3940213.
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18
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Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Mar; 37(6):630-9.
Patel NS, Peterson MR, Brenner DA, Heba E, Sirlin C, Loomba R. PMID: 23383649; PMCID: PMC4136524.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31.
Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. PMID: 23382291; PMCID: PMC3632805.
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PubMed Mentions:
239 Fields:
Translation:
Humans
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Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. Gastroenterology. 2013 May; 144(5):1042-1054.e4.
Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E. PMID: 23391818; PMCID: PMC3752402.
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PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
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Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study. Am J Epidemiol. 2013 02 15; 177(4):333-42.
Loomba R, Yang HI, Su J, Brenner D, Barrett-Connor E, Iloeje U, Chen CJ. PMID: 23355498; PMCID: PMC3626057.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Prognostic implication of liver histology in patients with nonalcoholic fatty liver disease in diabetes. J Diabetes Complications. 2013 May-Jun; 27(3):293-300.
Doycheva I, Patel N, Peterson M, Loomba R. PMID: 23312215; PMCID: PMC4167586.
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14 Fields:
Translation:
Humans
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Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2012 Nov; 36(10):909-21.
Zarrinpar A, Loomba R. PMID: 23057494; PMCID: PMC3535499.
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PubMed Mentions:
51 Fields:
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Humans
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Nonalcoholic fatty liver disease: Indications for liver biopsy and noninvasive biomarkers. Clin Liver Dis (Hoboken). 2012 Sep; 1(4):104-107.
Noureddin M, Loomba R. PMID: 31186861; PMCID: PMC6499277.
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PubMed Mentions:
24
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Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis. Hepatology. 2012 Sep; 56(3):943-51.
Loomba R, Abraham M, Unalp A, Wilson L, Lavine J, Doo E, Bass NM, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 22505194; PMCID: PMC3407289.
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PubMed Mentions:
217 Fields:
Translation:
Humans
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Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. J Clin Exp Hepatol. 2012 Jun; 2(2):156-73.
Le TA, Loomba R. PMID: 25755424; PMCID: PMC3940181.
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16
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Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology. 2012 Sep; 56(3):922-32.
Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R, San Diego Integrated NAFLD Research Consortium (SINC). PMID: 22431131; PMCID: PMC3400720.
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PubMed Mentions:
136 Fields:
Translation:
Humans
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Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther. 2012 Jul; 36(1):22-9.
Permutt Z, Le TA, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. PMID: 22554256; PMCID: PMC3437221.
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PubMed Mentions:
163 Fields:
Translation:
Humans
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Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. PLoS One. 2012; 7(4):e34218.
Lee JK, Bettencourt R, Brenner D, Le TA, Barrett-Connor E, Loomba R. PMID: 22514624; PMCID: PMC3325993.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Meta-analysis: pioglitazone improves liver histology and fibrosis in patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2012 Jan; 35(1):66-75.
Boettcher E, Csako G, Pucino F, Wesley R, Loomba R. PMID: 22050199; PMCID: PMC3488596.
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125 Fields:
Translation:
Humans
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Serum levels of alanine aminotransferase decrease with age in longitudinal analysis. Clin Gastroenterol Hepatol. 2012 Mar; 10(3):285-90.e1.
Dong MH, Bettencourt R, Brenner DA, Barrett-Connor E, Loomba R. PMID: 22020064; PMCID: PMC3288181.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Family history of peripheral artery disease is associated with prevalence and severity of peripheral artery disease: the San Diego population study. J Am Coll Cardiol. 2011 Sep 20; 58(13):1386-92.
Wassel CL, Loomba R, Ix JH, Allison MA, Denenberg JO, Criqui MH. PMID: 21920269; PMCID: PMC3215334.
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25 Fields:
Translation:
Humans
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Alanine aminotransferase decreases with age: the Rancho Bernardo Study. PLoS One. 2010 Dec 08; 5(12):e14254.
Dong MH, Bettencourt R, Barrett-Connor E, Loomba R. PMID: 21170382; PMCID: PMC2999530.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men. Clin Gastroenterol Hepatol. 2010 Oct; 8(10):891-8, 898.e1-2.
Loomba R, Yang HI, Su J, Brenner D, Iloeje U, Chen CJ. PMID: 20621202.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins. Gastroenterology. 2010 Sep; 139(3):836-45, 845.e1.
Loomba R, Rao F, Zhang L, Khandrika S, Ziegler MG, Brenner DA, O'Connor DT. PMID: 20537997; PMCID: PMC3038676.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Advances in pediatric nonalcoholic fatty liver disease. Hepatology. 2009 Oct; 50(4):1282-93.
Loomba R, Sirlin CB, Schwimmer JB, Lavine JE. PMID: 19637286; PMCID: PMC2757471.
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PubMed Mentions:
96 Fields:
Translation:
Humans
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Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: the Rancho Bernardo Study. Aliment Pharmacol Ther. 2009 Dec 01; 30(11-12):1137-49.
Loomba R, Bettencourt R, Barrett-Connor E. PMID: 19737152; PMCID: PMC3220929.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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Drug targets in hepatitis B virus infection. Infect Disord Drug Targets. 2009 Apr; 9(2):105-16.
Stein LL, Loomba R. PMID: 19275699; PMCID: PMC6658185.
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PubMed Mentions:
9 Fields:
Translation:
HumansCellsPHPublic Health
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Role of fluoroquinolones in the primary prophylaxis of spontaneous bacterial peritonitis: meta-analysis. Clin Gastroenterol Hepatol. 2009 Apr; 7(4):487-493.
Loomba R, Wesley R, Bain A, Csako G, Pucino F. PMID: 19250986; PMCID: PMC5807076.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Placebo in nonalcoholic steatohepatitis: insight into natural history and implications for future clinical trials. Clin Gastroenterol Hepatol. 2008 Nov; 6(11):1243-8.
Loomba R, Wesley R, Pucino F, Liang TJ, Kleiner DE, Lavine JE. PMID: 18829391; PMCID: PMC3133944.
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17 Fields:
Translation:
Humans
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Hepatitis B immunoglobulin and Lamivudine improve hepatitis B-related outcomes after liver transplantation: meta-analysis. Clin Gastroenterol Hepatol. 2008 Jun; 6(6):696-700.
Loomba R, Rowley AK, Wesley R, Smith KG, Liang TJ, Pucino F, Csako G. PMID: 18456569; PMCID: PMC2729093.
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Systematic review: the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy. Ann Intern Med. 2008 Apr 01; 148(7):519-28.
Loomba R, Rowley A, Wesley R, Liang TJ, Hoofnagle JH, Pucino F, Csako G. PMID: 18378948; PMCID: PMC2729097.
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176 Fields:
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Humans
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Treatment of chronic hepatitis B. Antivir Ther. 2007; 12 Suppl 3:H33-41.
Loomba R, Liang TJ. PMID: 18284181.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells