Benjamin Gastfriend

Title(s)	Postdoctoral Scholar, Pharmacology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Biography

Education and Training

University of Maryland, College Park, MD	BS	05/2016	Chemical Engineering
University of Wisconsin, Madison, WI	PhD	05/2022	Chemical Engineering

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest. Sci Adv. 2024 Feb 02; 10(5):eadi1737. Gastfriend BD, Snyder ME, Holt HE, Daneman R, Palecek SP, Shusta EV. PMID: 38306433; PMCID: PMC10836734.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Humans Cells
Dural mural cells paint an anti-inflammatory picture. J Exp Med. 2024 Feb 05; 221(2). Lummis NC, Gastfriend BD, Daneman R. PMID: 38270593; PMCID: PMC10818063.

View in: PubMed Mentions: Fields:
All Allergy and Immunology Med Medicine (General)
Translation:Humans
Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis. Brain. 2022 12 19; 145(12):4334-4348. Nishihara H, Perriot S, Gastfriend BD, Steinfort M, Cibien C, Soldati S, Matsuo K, Guimbal S, Mathias A, Palecek SP, Shusta EV, Pasquier RD, Engelhardt B. PMID: 35085379; PMCID: PMC10200307.

View in: PubMed Mentions: 19 Fields:
Bra Brain Neu Neurology
Translation:Humans Cells
Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier. Pharm Res. 2022 Jul; 39(7):1523-1534. Ye Z, Gastfriend BD, Umlauf BJ, Lynn DM, Shusta EV. PMID: 35169958; PMCID: PMC9250590.

View in: PubMed Mentions: 6 Fields:
Pha Pharmacology
Translation:Humans Animals
Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. Elife. 2021 11 10; 10. Gastfriend BD, Nishihara H, Canfield SG, Foreman KL, Engelhardt B, Palecek SP, Shusta EV. PMID: 34755601; PMCID: PMC8664294.

View in: PubMed Mentions: 16 Fields:
Bio Biology
Translation:Humans Cells
A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology. Nat Med. 2021 09; 27(9):1600-1606. Wang L, Sievert D, Clark AE, Lee S, Federman H, Gastfriend BD, Shusta EV, Palecek SP, Carlin AF, Gleeson JG. PMID: 34244682; PMCID: PMC8601037.

View in: PubMed Mentions: 64 Fields:
Med Medicine (General)Mol Molecular Biology
Translation:Humans Cells
Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions. STAR Protoc. 2021 06 18; 2(2):100563. Nishihara H, Gastfriend BD, Kasap P, Palecek SP, Shusta EV, Engelhardt B. PMID: 34151293; PMCID: PMC8188617.

View in: PubMed Mentions: 7 Fields:
Bio Biology Sci Science
Translation:Humans Cells
Integrative analysis of the human brain mural cell transcriptome. J Cereb Blood Flow Metab. 2021 11; 41(11):3052-3068. Gastfriend BD, Foreman KL, Katt ME, Palecek SP, Shusta EV. PMID: 34027687; PMCID: PMC8756477.

View in: PubMed Mentions: 8 Fields:
Bra Brain Met Metabolism Vas Vascular Diseases
Translation:Humans Animals Cells
Differentiation of Brain Pericyte-Like Cells from Human Pluripotent Stem Cell-Derived Neural Crest. Curr Protoc. 2021 Jan; 1(1):e21. Gastfriend BD, Stebbins MJ, Du F, Shusta EV, Palecek SP. PMID: 33484491; PMCID: PMC7839246.

View in: PubMed Mentions: 5 Fields:
Sci Science
Translation:Humans Cells
Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions. FASEB J. 2020 12; 34(12):16693-16715. Nishihara H, Gastfriend BD, Soldati S, Perriot S, Mathias A, Sano Y, Shimizu F, Gosselet F, Kanda T, Palecek SP, Du Pasquier R, Shusta EV, Engelhardt B. PMID: 33124083; PMCID: PMC7686106.

View in: PubMed Mentions: 28 Fields:
Bio Biology Phy Physiology
Translation:Humans Cells
Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction. Lab Chip. 2020 10 21; 20(20):3744-3756. Qian T, Gil DA, Contreras Guzman E, Gastfriend BD, Tweed KE, Palecek SP, Skala MC. PMID: 33048070; PMCID: PMC7699819.

View in: PubMed Mentions: 2 Fields:
Bio Biotechnology Che Chemistry
Translation:Humans Cells
Immobilized metal affinity chromatography optimization for poly-histidine tagged proteins. J Chromatogr A. 2020 Oct 11; 1629:461505. Riguero V, Clifford R, Dawley M, Dickson M, Gastfriend B, Thompson C, Wang SC, O'Connor E. PMID: 32861092.

View in: PubMed Mentions: 12 Fields:
Che Chemistry Techniques
Translation:Humans Animals Cells
Antibody screening using a human iPSC-based blood-brain barrier model identifies antibodies that accumulate in the CNS. FASEB J. 2020 09; 34(9):12549-12564. Georgieva JV, Goulatis LI, Stutz CC, Canfield SG, Song HW, Gastfriend BD, Shusta EV. PMID: 32960493; PMCID: PMC7513543.

View in: PubMed Mentions: 15 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Transcriptomic comparison of human and mouse brain microvessels. Sci Rep. 2020 07 23; 10(1):12358. Song HW, Foreman KL, Gastfriend BD, Kuo JS, Palecek SP, Shusta EV. PMID: 32704093; PMCID: PMC7378255.

View in: PubMed Mentions: 57 Fields:
Sci Science
Translation:Humans Animals Cells
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells. Fluids Barriers CNS. 2019 Aug 22; 16(1):26. Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV. PMID: 31434575; PMCID: PMC6704684.

View in: PubMed Mentions: 12 Fields:
Bra Brain Neu Neurology
Translation:Humans Animals Cells
An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons. Fluids Barriers CNS. 2019 Aug 07; 16(1):25. Canfield SG, Stebbins MJ, Faubion MG, Gastfriend BD, Palecek SP, Shusta EV. PMID: 31387594; PMCID: PMC6685239.

View in: PubMed Mentions: 41 Fields:
Bra Brain Neu Neurology
Translation:Humans Animals Cells
Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties. Sci Adv. 2019 03; 5(3):eaau7375. Stebbins MJ, Gastfriend BD, Canfield SG, Lee MS, Richards D, Faubion MG, Li WJ, Daneman R, Palecek SP, Shusta EV. PMID: 30891496; PMCID: PMC6415958.

View in: PubMed Mentions: 89 Fields:
Sci Science
Translation:Humans Animals Cells
Preventing S. aureus biofilm formation on titanium surfaces by the release of antimicrobial β-peptides from polyelectrolyte multilayers. Acta Biomater. 2019 07 15; 93:50-62. Rodríguez López AL, Lee MR, Ortiz BJ, Gastfriend BD, Whitehead R, Lynn DM, Palecek SP. PMID: 30831325; PMCID: PMC6693497.

View in: PubMed Mentions: 15 Fields:
Bio Biomedical Engineering
Translation:Animals Cells
Modeling the blood-brain barrier: Beyond the endothelial cells. Curr Opin Biomed Eng. 2018 Mar; 5:6-12. Gastfriend BD, Palecek SP, Shusta EV. PMID: 29915815; PMCID: PMC6003712.

View in: PubMed Mentions: 46