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Anthony O'donoghue

Photo of Anthony O'donoghue
Title(s)Associate Professor, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0001-5695-0409 Additional info
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    Collapse Biography 
    Collapse education and training
    University of California San FranciscoAssociate Specialist2015Pharmaceutical Chemistry
    University of California San FranciscoPost-Doctoral Training2011Pharmaceutical Chemistry
    National University of Ireland, GalwayPh.D2005Biochemistry
    National University of Ireland, GalwayB.S.2000Biochemistry
    Cork Institute of Technology, IrelandNational Diploma1998Cell & Molecular Biology
    Collapse awards and honors
    NIH/NIBIB2019  - 2022Trailblazer Awardee
    International Proteolysis Society2019  - 2023President
    International Proteolysis Society2017  - 2019Member of Council - Treasurer
    Future Science2013  - 2013Bioanalysis Young Investigator Award
    National University of Ireland, Galway2002  - 2003UC Education Abroad Scholarship

    Collapse Overview 
    Collapse overview
    My laboratory interests lie in the detection and characterization of proteolytic enzymes that are involved in disease. In particular, we are interested in understanding the role of peptidases/proteases at host-pathogen and tumor-stroma interfaces. Our research utilizes a mass spectrometry based platform technology to uncover the global proteolytic activity in complex biological samples such as the secretions of cancer cells and infectious organisms. Our workflow also includes in-depth proteomic analysis to identify the enzymes. Knowledge of which peptidases are functionally active in diseased tissue and not active in healthy tissue allow us to 1) develop peptidase inhibitors to shut down the function, 2) generate peptidase-activated imaging agents to locate the disease or 3) develop peptidase-activated drugs to aid in the delivery of toxic compounds to the site of disease. Using this technology, we have uncovered novel proteolytic activities in gastric juice, pancreatic cyst fluid, serum and neutrophil extracts. In addition our group is highly collaborative and we routinely generate substrate specificity profiles of endo- and exo-peptidases that have been isolated from diverse organisms that includes ticks, crustaceans and parasitic worms.

    Collapse Research 
    Collapse research activities and funding
    Tumor-specific drug activation by pericellular proteases
    NCI R21CA256460Feb 1, 2022 - Jan 31, 2023
    Role: Principal Investigator
    Proteasome inhibitors against mucosal protozoan pathogens
    NIH R01AI158612Sep 22, 2021 - Aug 31, 2026
    Role: Co-Principal Investigator
    Quantification of Proteolytic Activity in Human Milk using Mass Spectrometry
    MOMI Seeds Pilot Grant MOMI 2020Jan 1, 2020 - Jan 1, 2021
    Role: Principal Investigator
    Point-of-Care Quantitation of Sputum Neutrophil Elastase Activity in Chronic Airway Disease
    NIH R21EB028485Jul 1, 2019 - Mar 31, 2022
    Role: Principal Investigator
    Selective proteasome inhibitors for trichomoniasis
    NIH R21AI146387Jul 1, 2019 - Jun 30, 2021
    Role: Co-Principal Investigator
    Global identification of novel protease activity for Coccidioides, the Valley fever pathogen
    NIH/NIAID R21AI140020Jun 22, 2018 - May 31, 2020
    Role: Sub-award PI
    Exploring the proteasome as a new drug target to treat schistosomiasis
    NIH R21AI133393Jun 23, 2017 - May 31, 2019
    Role: Principal Investigator
    Global Profiling of Extracellular Protease Activity from Lung Cancer Cells
    American Cancer Society Institute Research Grant Dec 15, 2016 - Dec 14, 2016
    Role: Principal Investigator
    Global analysis of age-related changes to peptide and protease signaling using patient-derived, age-preserved induced neurons
    UC San Diego Center for Healthy Aging Oct 1, 2016 - Sep 30, 2017
    Role: Principal Investigator
    Rapid Point-of-Care Detection of Candidemia in Serum
    UC San Diego CTRI Apr 1, 2016 - Mar 31, 2017
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur. Biochem J. 2025 Nov 28. Chua W, Hei Y, Koh LF, Yap BLH, Saw HL, Fernandes THM, da Silva EB, Goh S, Dawson TL, O'Donoghue AJ, Common JE, Li H. PMID: 41332240.
      View in: PubMed   Mentions:
    2. Discovery of benzyl carbamate inhibitors of coronavirus Mpro enzymes from a legacy collection of cysteine protease inhibitors. J Enzyme Inhib Med Chem. 2025 Dec; 40(1):2585619. Sá Magalhães Serafim M, Kronenberger T, Francisco KR, de Sousa Reis EV, Gonçalves de Oliveira E, Marcelino E Oliveira FK, Serraglio Fortes I, Maciel Fernandes TH, Barbosa da Silva E, Fajtova P, Skinner DE, Syed RO, Lage de Siqueira-Neto J, Poso A, Fernandes Mota BE, Alves Coelho-Dos-Reis JG, Santos Abrahão J, Gonçalves Maltarollo V, O'Donoghue AJ, Caffrey CR. PMID: 41246830.
      View in: PubMed   Mentions:
    3. Inhibitors of the 20S proteasome ß5 subunit as potent and selective agents against Trichomonas vaginalis. Antimicrob Agents Chemother. 2025 Nov 11; e0089325. Miyamoto Y, Hurysz BM, Fajtova P, Eckmann P, Serafim MSM, Kronenberger T, Al-Hindy M, Dekker PM, Maurits E, Overkleeft HS, Bergdahl BM, Almaliti J, Gerwick WH, O'Donoghue AJ, Eckmann L. PMID: 41218108.
      View in: PubMed   Mentions:
    4. Aza-peptide aldehydes and ketones: synthesis and evaluation as human 20S proteasome inhibitors. Future Med Chem. 2025 Oct; 17(20):2479-2492. Corrigan TS, Border SE, Lotti Diaz LM, Kasper KQ, Noonchester AM, Amer R, Kucway KS, Fleisher M, Fernandez JP, Lovins AR, Serrano AK, Caffrey CR, O'Donoghue AJ, Benson DM, Hadad CM, Ekici ÖD. PMID: 41099163; PMCID: PMC12536793.
      View in: PubMed   Mentions:
    5. The impact of pH on proteolytic activity in wound fluid: Implications for acid therapy. J Biol Chem. 2025 Oct; 301(10):110723. Barbosa da Silva E, Crane MJ, Liu L, Gelsinger DJ, Jordon ARD, Le P, Haggett JG, Myers SA, McKinney RL, Eberson CP, Jamieson AM, O'Donoghue AJ. PMID: 40962052; PMCID: PMC12550788.
      View in: PubMed   Mentions:    Fields:    
    6. Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity. J Med Chem. 2025 Sep 25; 68(18):19339-19376. Flury P, Vishwakarma J, Sylvester K, Higashi-Kuwata N, Dabrowska AK, Delgado R, Cuell A, Basu R, Taylor AB, de Oliveira EG, Magalhães Serafim MS, Qiao J, Chen Y, Yang S, O'Donoghue AJ, Mitsuya H, Gütschow M, Laufer SA, Müller CE, Harris RS, Pillaiyar T. PMID: 40932417; PMCID: PMC12481482.
      View in: PubMed   Mentions:    Fields:    
    7. Development of Macrocyclic Peptide-Based Proteasome Inhibitors with Enhanced Blood-Brain Barrier Penetration for Treating Brain Neoplasms. J Med Chem. 2025 Sep 25; 68(18):18908-18929. Almaliti J, Al-Hindy M, Fajtová P, Glukhov E, Berger T, Graf Y, Hoffmann da Silva CE, Huang C, Azizyan N, He Y, O'Donoghue AJ, Gerwick WH. PMID: 40922058.
      View in: PubMed   Mentions:    Fields:    
    8. Discovery and characterization of protease activities in acidified bovine milk. Food Chem. 2025 Nov 30; 493(Pt 2):145713. Racca T, Pedersen AL, Maciel Fernandes TH, Goulding D, O'Regan J, Affolter M, Kelly AL, O'Donoghue AJ. PMID: 40782634.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. Neutral pH-Selective Inhibition of Cytosolic Cathepsin B: A Novel Drug Targeting Strategy for Traumatic Brain Injury and Alzheimer's Disease. ACS Chem Biol. 2025 Aug 15; 20(8):1841-1848. Hook V, Podvin S, Yoon MC, Phan VV, Florio J, Spencer B, Mosier C, Cheng A, Ahuett S, Almaliti J, Gerwick WH, Rissman RA, O'Donoghue AJ. PMID: 40700403; PMCID: PMC12362428.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Substrate profiling of marine-derived thermotolerant cysteine protease reveals unique cleavage preferences for industrial applications. Sci Rep. 2025 Jul 21; 15(1):26481. Røyseth V, Hurysz BM, Arsin H, Vazquez JM, Kaczorowska AK, Fedøy AE, Biernacka D, Dorawa S, Kaczorowski T, Stokke R, O'Donoghue AJ, Steen IH. PMID: 40691222; PMCID: PMC12280095.
      View in: PubMed   Mentions:    Fields:    
    11. Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Human 20S Proteasome Inhibitors: Extension to the Prime Site. ACS Omega. 2025 Jul 29; 10(29):31549-31567. Border SE, Lotti Diaz LM, Amer R, Noonchester AM, Kucway KS, Fleisher M, Fernandez JP, Lovins AR, Corrigan TS, Serrano AK, Caffrey CR, O'Donoghue AJ, Benson DM, Hadad CM, Dogan Ekici Ö. PMID: 40757351; PMCID: PMC12311731.
      View in: PubMed   Mentions:
    12. Chalcogen Derivatives for the Treatment of African Trypanosomiasis: Biological Evaluation of Thio- and Seleno-Semicarbazones and Their Azole Derivatives. ACS Omega. 2025 Jun 17; 10(23):24872-24886. Rubio-Hernández M, Teixeira TR, Nguyen TP, Shingyoji M, da Silva EB, O'Donoghue AJ, Caffrey CR, Pérez-Silanes S, Martínez-Sáez N. PMID: 40547650; PMCID: PMC12177781.
      View in: PubMed   Mentions:
    13. Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates. Protein Sci. 2025 Jun; 34(6):e70180. Silva EB, Jiang Z, Liu C, Fajtová P, Teixeira TR, de Castro Fiorini Maia G, Liu LJ, El-Sakkary N, Skinner DE, Syed A, Wang SC, Caffrey CR, O'Donoghue AJ. PMID: 40411405; PMCID: PMC12102734.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Activation of Cytosolic Cathepsin B Activity in the Brain by Traumatic Brain Injury and Inhibition by the Neutral pH Selective Inhibitor Probe Z-Arg-Lys-AOMK. ACS Chem Neurosci. 2025 Apr 02; 16(7):1297-1308. Podvin S, Florio J, Spencer B, Mante M, Guzman E, Arias C, Mosier C, Phan VV, Yoon MC, Almaliti J, O'Donoghue AJ, Gerwick WH, Rissman RA, Hook V. PMID: 40130579; PMCID: PMC11969537.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    15. Structural Insights into Salinosporamide a Mediated Inhibition of the Human 20S Proteasome. Molecules. 2025 Mar 20; 30(6). Sülzen H, Fajtova P, O'Donoghue AJ, Silhan J, Boura E. PMID: 40142161; PMCID: PMC11946101.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in Salinispora. Mar Drugs. 2025 Mar 14; 23(3). Castro-Falcón G, Guillén-Matus DG, Silva EBD, Guo W, Ross A, Sá Magalhães Serafim M, Fernandes THM, Tantillo DJ, O'Donoghue AJ, Jensen PR. PMID: 40137312; PMCID: PMC11943689.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    17. An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4. J Biol Chem. 2025 Mar; 301(3):108275. Bhaduri S, Braza MKE, Stanchev S, Tauber M, Al-Bawab R, Liu LJ, Trujillo DF, Solorio-Kirpichyan K, Srivastava A, Sanlley-Hernandez J, O'Donoghue AJ, Lemberg MK, Amaro R, Strisovsky K, Neal SE. PMID: 39922490; PMCID: PMC11929074.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system. PLoS Negl Trop Dis. 2025 Feb; 19(2):e0012555. O'Donoghue AJ, Liu C, Simington CJ, Montermoso S, Moreno-Galvez E, Serafim MSM, Burata OE, Lucero RM, Nguyen JT, Fong D, Tran K, Millan N, Gallimore JM, Parungao K, Fong J, Suzuki BM, Jiang Z, Isoe J, Rascón AA. PMID: 39913535; PMCID: PMC11838913.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    19. Repurposing Diflunisal as an Antivirulence Agent Against Staphylococcus aureus. Infect Microbes Dis. 2025 Mar; 7(1):43-53. Sun D, Haste NM, Sun J, Serafim MSM, Salvioni A, Olson J, Cole J, Okumura C, Gallo RL, Sakoulas G, O'Donoghue AJ, Hensler ME, Nizet V. PMID: 40808982; PMCID: PMC12345599.
      View in: PubMed   Mentions:
    20. Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity. J Med Chem. 2025 Feb 13; 68(3):3626-3652. Flury P, Krüger N, Sylvester K, Breidenbach J, Al Hamwi G, Qiao J, Chen Y, Rocha C, Serafim MSM, Barbosa da Silva E, Pöhlmann S, Poso A, Kronenberger T, Rox K, O'Donoghue AJ, Yang S, Sträter N, Gütschow M, Laufer SA, Müller CE, Pillaiyar T. PMID: 39813204.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. A multiplex method for rapidly identifying viral protease inhibitors. Mol Syst Biol. 2025 Feb; 21(2):158-172. Hong SJ, Resnick SJ, Iketani S, Cha JW, Albert BA, Fazekas CT, Chang CW, Liu H, Dagan S, Abagyan MR, Fajtová P, Culbertson B, Brace B, Reddem ER, Forouhar F, Glickman JF, Balkovec JM, Stockwell BR, Shapiro L, O'Donoghue AJ, Sabo Y, Freundlich JS, Ho DD, Chavez A. PMID: 39762652; PMCID: PMC11790949.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Pyrazinyl-Substituted Aminoazoles as Covalent Inhibitors of Thrombin: Synthesis, Structure, and Anticoagulant Properties. ACS Pharmacol Transl Sci. 2025 Jan 10; 8(1):146-172. Imberg L, Siutkina AI, Erbacher C, Schmidt J, Broekmans DF, Ovsepyan RA, Daniliuc CG, Gonçalves de Oliveira E, Serafim MSM, O'Donoghue AJ, Pillaiyar T, Panteleev MA, Poso A, Kalinina SA, Bermúdez M, Nekipelov K, Bendas G, Karst U, Kalinin DV. PMID: 39816788; PMCID: PMC11730114.
      View in: PubMed   Mentions: 1  
    23. Distinct substrate specificities of the three catalytic subunits of the Trichomonas vaginalis proteasome. Protein Sci. 2024 Dec; 33(12):e5225. Fajtova P, Hurysz BM, Miyamoto Y, Serafim MSM, Jiang Z, Vazquez JM, Trujillo DF, Liu LJ, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, McMinn DL, Kirk CJ, Boura E, Eckmann L, O'Donoghue AJ. PMID: 39589076; PMCID: PMC11590128.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and In Vivo Efficacy. ACS Infect Dis. 2024 Dec 13; 10(12):4182-4193. Liu LJ, Francisco KR, Sun YU, Serafim MSM, Amarasinghe DK, Teixeira TR, Lucero B, Kronenberger T, Elsayed W, Elwakeel H, Al-Hindy M, Almaliti J, Gerwick WH, O'Donoghue AJ, Caffrey CR. PMID: 39589805; PMCID: PMC11650654.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    25. Development of an Antiviral Medicinal Plant and Natural Product Database (avMpNp Database) from Biodiversity. Chem Biodivers. 2024 Dec; 21(12):e202400285. Quadros de Azevedo D, Vinícius Viera Nóia J, Ribeiro YCM, Alves Dos Reis R, Ribeiro PHO, Almeida Moura G, Mendes P, Barbosa de Souza AB, Carpini Mermejo S, Serafim MSM, Fernandes THM, O'Donoghue AJ, Campos ACFA, Campos SVA, Gonçalves Maltarollo V, Oliveira Castilho R. PMID: 39546588.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    26. Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (S, Se) and Their Azole Derivatives against Chagas Disease. J Med Chem. 2024 Nov 14; 67(21):19038-19056. Rubio-Hernández M, Alcolea V, Barbosa da Silva E, Giardini MA, M Fernandes TH, Martínez-Sáez N, O'Donoghue AJ, Siqueira-Neto JL, Pérez-Silanes S. PMID: 39485736; PMCID: PMC12320831.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    27. Evaluating Antimalarial Proteasome Inhibitors for Efficacy in Babesia Blood Stage Cultures. ACS Omega. 2024 Nov 12; 9(45):44989-44999. Robbertse L, Fajtová P, Šnebergerová P, Jalovecká M, Levytska V, Barbosa da Silva E, Sharma V, Pachl P, Almaliti J, Al-Hindy M, Gerwick WH, Boura E, O'Donoghue AJ, Sojka D. PMID: 39554424; PMCID: PMC11561622.
      View in: PubMed   Mentions: 4  
    28. Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors. Nat Commun. 2024 10 04; 15(1):8621. Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. PMID: 39366995; PMCID: PMC11452676.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    29. Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis. PLoS One. 2024; 19(10):e0308672. Nieskens NM, Miyamoto Y, Hurysz BM, O'Donoghue AJ, Eckmann L. PMID: 39352907; PMCID: PMC11444383.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    30. The proteasome as a drug target for treatment of parasitic diseases. Adv Parasitol. 2024; 126:53-96. Liu LJ, O'Donoghue AJ, Caffrey CR. PMID: 39448194.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    31. Clickable Probes for Pathogen Proteasomes: Synthesis and Applications. ACS Omega. 2024 Aug 13; 9(32):34829-34840. Liu LJ, Lucero B, Manriquez-Rodriguez C, Francisco KR, Teixeira TR, Yohannan DJ, Ballatore C, Myers SA, O'Donoghue AJ, Caffrey CR. PMID: 39157084; PMCID: PMC11325529.
      View in: PubMed   Mentions: 1  
    32. Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin. Protein Sci. 2024 Aug; 33(8):e5110. Mahoney MW, Helander J, Kooner AS, Norman M, Damalanka VC, De Bona P, Kasperkiewicz P, Rut W, Poreba M, Kashipathy MM, Battaile KP, Lovell S, O'Donoghue AJ, Craik CS, Drag M, Janetka JW. PMID: 39073183; PMCID: PMC11284329.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    33. Small molecule in situ resin capture provides a compound first approach to natural product discovery. Nat Commun. 2024 Jun 19; 15(1):5230. Bogdanov A, Salib MN, Chase AB, Hammerlindl H, Muskat MN, Luedtke S, da Silva EB, O'Donoghue AJ, Wu LF, Altschuler SJ, Molinski TF, Jensen PR. PMID: 38898025; PMCID: PMC11187115.
      View in: PubMed   Mentions: 6     Fields:    
    34. AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep. 2024 04 02; 14(1):7526. Atomwise AIMS Program. PMID: 38565852; PMCID: PMC10987645.
      View in: PubMed   Mentions: 35     Fields:    
    35. A GMR enzymatic assay for quantifying nuclease and peptidase activity. Front Bioeng Biotechnol. 2024; 12:1363186. Sveiven M, Serrano AK, Rosenberg J, Conrad DJ, Hall DA, O'Donoghue AJ. PMID: 38544982; PMCID: PMC10966768.
      View in: PubMed   Mentions: 1  
    36. Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS Omega. 2024 Jan 23; 9(3):3997-4003. Almaliti J, Alhindy M, Yoon MC, Hook V, Molinski TF, O'Donoghue AJ, Gerwick WH. PMID: 38284081; PMCID: PMC10809369.
      View in: PubMed   Mentions: 1  
    37. Valence-driven colorimetric detection of norovirus protease via peptide-AuNP interactions. Chem Commun (Camb). 2023 Oct 17; 59(83):12459-12462. Ling C, Jin Z, Yeung J, da Silva EB, Chang YC, He T, Yim W, O'Donoghue AJ, Jokerst JV. PMID: 37782049.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    38. A Malassezia pseudoprotease dominates the secreted hydrolase landscape and is a potential allergen on skin. Biochimie. 2024 Jan; 216:181-193. Chua W, Marsh CO, Poh SE, Koh WL, Lee MLY, Koh LF, Tang XE, See P, Ser Z, Wang SM, Sobota RM, Dawson TL, Yew YW, Thng S, O'Donoghue AJ, Oon HH, Common JE, Li H. PMID: 37748748.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    39. A dual-binding magnetic immunoassay to predict spontaneous preterm birth. Front Bioeng Biotechnol. 2023; 11:1256267. Sveiven M, Gassman A, Rosenberg J, Chan M, Boniface J, O'Donoghue AJ, Laurent LC, Hall DA. PMID: 37790251; PMCID: PMC10542577.
      View in: PubMed   Mentions: 1  
    40. An approach to zwitterionic peptide design for colorimetric detection of the Southampton norovirus SV3CP protease. Analyst. 2023 Sep 11; 148(18):4504-4512. Yeung J, Jin Z, Ling C, Retout M, Barbosa da Silva E, Damani M, Chang YC, Yim W, O'Donoghue AJ, Jokerst JV. PMID: 37578304; PMCID: PMC10614164.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    41. A Protease-Responsive Polymer/Peptide Conjugate and Reversible Assembly of Silver Clusters for the Detection of Porphyromonas gingivalis Enzymatic Activity. ACS Nano. 2023 09 12; 17(17):17308-17319. Retout M, Amer L, Yim W, Creyer MN, Lam B, Trujillo DF, Potempa J, O'Donoghue AJ, Chen C, Jokerst JV. PMID: 37602819; PMCID: PMC10561899.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    42. Endoproteolysis of Oligopeptide-Based Coacervates for Enzymatic Modeling. ACS Nano. 2023 09 12; 17(17):16980-16992. Jin Z, Ling C, Yim W, Chang YC, He T, Li K, Zhou J, Cheng Y, Li Y, Yeung J, Wang R, Fajtová P, Amer L, Mattoussi H, O'Donoghue AJ, Jokerst JV. PMID: 37579082; PMCID: PMC10614163.
      View in: PubMed   Mentions: 4     Fields:    
    43. Synthesis of indole-based ferulic acid derivatives and in vitro evaluation of antiviral activity against SARS-CoV-2. Medicinal Chemistry Research. 2023; (32):2256-2267. Marina Mol SA Verzola, Daisymara Priscila de Almeida Marques, Elany Barbosa da Silva, Mateus Sá Magalhães Serafim, Rafaela Salgado Ferreira, Pavla Fajtová, Markus Kohlhoff, Anthony John O’Donoghue, Vinícius Gonçalves Maltarollo, Jordana Grazziela Alves Coelho-dos-Reis, Renata Barbosa de Oliveira. View Publication.
    44. Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors. Protein Sci. 2023 08; 32(8):e4712. Fink EA, Bardine C, Gahbauer S, Singh I, Detomasi TC, White K, Gu S, Wan X, Chen J, Ary B, Glenn I, O'Connell J, O'Donnell H, Fajtová P, Lyu J, Vigneron S, Young NJ, Kondratov IS, Alisoltani A, Simons LM, Lorenzo-Redondo R, Ozer EA, Hultquist JF, O'Donoghue AJ, Moroz YS, Taunton J, Renslo AR, Irwin JJ, García-Sastre A, Shoichet BK, Craik CS. PMID: 37354015; PMCID: PMC10364469.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic Health
    45. The importance of good practices and false hits for QSAR-driven virtual screening real application: a SARS-CoV-2 main protease (M pro) case study. Frontiers in Drug Discovery. 2023; 3:1237655. Mateus Sá Magalhães Serafim, Simone Queiroz Pantaleão, Elany Barbosa da Silva, James McKerrow, Anthony J O'Donoghue, Bruno Fernandes Mota, Kathia M Honorio, Vinícius Gonçalves Maltarollo. View Publication.
    46. Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range. Biochemistry. 2023 08 01; 62(15):2289-2300. Yoon MC, Phan V, Podvin S, Mosier C, O'Donoghue AJ, Hook V. PMID: 37459182; PMCID: PMC10399199.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
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    100. The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS Infect Dis. 2019 10 11; 5(10):1802-1812. Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. PMID: 31355632; PMCID: PMC7283364.
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    101. Molecular characterization and functional analysis of the Schistosoma mekongi Ca2+-dependent cysteine protease (calpain). Parasit Vectors. 2019 Jul 30; 12(1):383. Chaimon S, Limpanont Y, Reamtong O, Ampawong S, Phuphisut O, Chusongsang P, Ruangsittichai J, Boonyuen U, Watthanakulpanich D, O'Donoghue AJ, Caffrey CR, Adisakwattana P. PMID: 31362766; PMCID: PMC6668146.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsPHPublic Health
    102. Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome. Microbiome. 2019 02 13; 7(1):23. Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, Dorrestein PC. PMID: 30760325; PMCID: PMC6375204.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    103. Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry. Mol Cell Proteomics. 2019 05; 18(5):968-981. Lapek JD, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. PMID: 30705125; PMCID: PMC6495252.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    104. Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. J Med Chem. 2019 01 24; 62(2):480-490. Damalanka VC, Han Z, Karmakar P, O'Donoghue AJ, La Greca F, Kim T, Pant SM, Helander J, Klefström J, Craik CS, Janetka JW. PMID: 30571119.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    105. An internally quenched peptide as a new model substrate for rhomboid intramembrane proteases. Biol Chem. 2018 11 27; 399(12):1389-1397. Arutyunova E, Jiang Z, Yang J, Kulepa AN, Young HS, Verhelst S, O'Donoghue AJ, Lemieux MJ. PMID: 30044760.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    106. Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome. Biol Chem. 2018 11 27; 399(12):1375-1388. Beekman C, Jiang Z, Suzuki BM, Palmer JM, Lindner DL, O'Donoghue AJ, Knudsen GM, Bennett RJ. PMID: 30367778.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    107. Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms. PLoS Negl Trop Dis. 2018 10; 12(10):e0006923. Rebello KM, McKerrow JH, Mota EM, O'Donoghue AJ, Neves-Ferreira AGC. PMID: 30379807; PMCID: PMC6231675.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    108. A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. ACS Chem Biol. 2018 09 21; 13(9):2513-2521. Xu JH, Jiang Z, Solania A, Chatterjee S, Suzuki B, Lietz CB, Hook VYH, O'Donoghue AJ, Wolan DW. PMID: 30085657; PMCID: PMC7293822.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    109. Validation of Babesia proteasome as a drug target. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):394-402. Jalovecka M, Hartmann D, Miyamoto Y, Eckmann L, Hajdusek O, O'Donoghue AJ, Sojka D. PMID: 30103207; PMCID: PMC6092455.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    110. SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. PLoS Negl Trop Dis. 2018 04; 12(4):e0006446. Leontovyc A, Ulrychová L, O'Donoghue AJ, Vondrášek J, Marešová L, Hubálek M, Fajtová P, Chanová M, Jiang Z, Craik CS, Caffrey CR, Mareš M, Dvorák J, Horn M. PMID: 29677188; PMCID: PMC5931690.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    111. Substrate Specificity of Cysteine Proteases Beyond the S2 Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L. Front Mol Biosci. 2018; 5:40. Corvo I, Ferraro F, Merlino A, Zuberbühler K, O'Donoghue AJ, Pastro L, Pi-Denis N, Basika T, Roche L, McKerrow JH, Craik CS, Caffrey CR, Tort JF. PMID: 29725596; PMCID: PMC5917446.
      View in: PubMed   Mentions: 11  
    112. Phosphopeptidomics Reveals Differential Phosphorylation States and Novel SxE Phosphosite Motifs of Neuropeptides in Dense Core Secretory Vesicles. J Am Soc Mass Spectrom. 2018 05; 29(5):935-947. Lietz CB, Toneff T, Mosier C, Podvin S, O'Donoghue AJ, Hook V. PMID: 29556927; PMCID: PMC5943185.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    113. Skin Commensal Malassezia globosa Secreted Protease Attenuates Staphylococcus aureus Biofilm Formation. J Invest Dermatol. 2018 05; 138(5):1137-1145. Li H, Goh BN, Teh WK, Jiang Z, Goh JPZ, Goh A, Wu G, Hoon SS, Raida M, Camattari A, Yang L, O'Donoghue AJ, Dawson TL. PMID: 29246799.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    114. Global substrate specificity profiling of post-translational modifying enzymes. Protein Sci. 2018 03; 27(3):584-594. Ivry SL, Meyer NO, Winter MB, Bohn MF, Knudsen GM, O'Donoghue AJ, Craik CS. PMID: 29168252; PMCID: PMC5818756.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    115. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. Elife. 2017 11 28; 6. Winter MB, La Greca F, Arastu-Kapur S, Caiazza F, Cimermancic P, Buchholz TJ, Anderl JL, Ravalin M, Bohn MF, Sali A, O'Donoghue AJ, Craik CS. PMID: 29182146; PMCID: PMC5705213.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    116. Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. J Med Chem. 2017 08 10; 60(15):6721-6732. LaMonte GM, Almaliti J, Bibo-Verdugo B, Keller L, Zou BY, Yang J, Antonova-Koch Y, Orjuela-Sanchez P, Boyle CA, Vigil E, Wang L, Goldgof GM, Gerwick L, O'Donoghue AJ, Winzeler EA, Gerwick WH, Ottilie S. PMID: 28696697; PMCID: PMC5554889.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    117. Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria. ACS Chem Biol. 2017 06 16; 12(6):1556-1565. Roncase EJ, Moon C, Chatterjee S, González-Páez GE, Craik CS, O'Donoghue AJ, Wolan DW. PMID: 28414448; PMCID: PMC5575927.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    118. Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts. Clin Cancer Res. 2017 Aug 15; 23(16):4865-4874. Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS. PMID: 28424202; PMCID: PMC5712228.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    119. Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs. Anal Chem. 2017 04 18; 89(8):4550-4558. Meyer NO, O'Donoghue AJ, Schulze-Gahmen U, Ravalin M, Moss SM, Winter MB, Knudsen GM, Craik CS. PMID: 28322550; PMCID: PMC5500290.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    120. Targeting proteasomes in infectious organisms to combat disease. FEBS J. 2017 05; 284(10):1503-1517. Bibo-Verdugo B, Jiang Z, Caffrey CR, O'Donoghue AJ. PMID: 28122162.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    121. Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence. PLoS Pathog. 2016 Dec; 12(12):e1006051. Clarke SC, Dumesic PA, Homer CM, O'Donoghue AJ, La Greca F, Pallova L, Majer P, Madhani HD, Craik CS. PMID: 27977806; PMCID: PMC5158083.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    122. Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors. Biol Chem. 2016 09 01; 397(9):871-81. O'Donoghue AJ, Ivry SL, Chaudhury C, Hostetter DR, Hanahan D, Craik CS. PMID: 27149201; PMCID: PMC5712230.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    123. IL-1β is an innate immune sensor of microbial proteolysis. Sci Immunol. 2016 Aug; 1(2). LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. PMID: 28331908; PMCID: PMC5358671.
      View in: PubMed   Mentions: 75     Fields:    
    124. Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria. PLoS Negl Trop Dis. 2016 08; 10(8):e0004893. Goupil LS, Ivry SL, Hsieh I, Suzuki BM, Craik CS, O'Donoghue AJ, McKerrow JH. PMID: 27501047; PMCID: PMC4976874.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    125. Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis. ACS Infect Dis. 2016 11 11; 2(11):807-815. Lentz CS, Ordonez AA, Kasperkiewicz P, La Greca F, O'Donoghue AJ, Schulze CJ, Powers JC, Craik CS, Drag M, Jain SK, Bogyo M. PMID: 27739665; PMCID: PMC5109297.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    126. Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles. Proc Natl Acad Sci U S A. 2016 Apr 05; 113(14):E2001-10. Julien O, Zhuang M, Wiita AP, O'Donoghue AJ, Knudsen GM, Craik CS, Wells JA. PMID: 27006500; PMCID: PMC4833263.
      View in: PubMed   Mentions: 65     Fields:    
    127. Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature. 2016 Feb 11; 530(7589):233-6. Li H, O'Donoghue AJ, van der Linden WA, Xie SC, Yoo E, Foe IT, Tilley L, Craik CS, da Fonseca PC, Bogyo M. PMID: 26863983; PMCID: PMC4755332.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    128. Complementary Proteomic and Biochemical Analysis of Peptidases in Lobster Gastric Juice Uncovers the Functional Role of Individual Enzymes in Food Digestion. Mar Biotechnol (NY). 2016 Apr; 18(2):201-14. Bibo-Verdugo B, O'Donoghue AJ, Rojo-Arreola L, Craik CS, García-Carreño F. PMID: 26613762.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    129. Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles. Biochimie. 2016 Mar; 122:99-109. Dvorák J, Fajtová P, Ulrychová L, Leontovyc A, Rojo-Arreola L, Suzuki BM, Horn M, Mareš M, Craik CS, Caffrey CR, O'Donoghue AJ. PMID: 26409899; PMCID: PMC4747843.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    130. Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24):7478-83. O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ. PMID: 25944934; PMCID: PMC4475985.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    131. Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor. Biochem J. 2015 Jan 01; 465(1):163-73. Sharma V, Panwar P, O'Donoghue AJ, Cui H, Guido RV, Craik CS, Brömme D. PMID: 25279554.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    132. Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. PLoS One. 2013; 8(9):e75141. O'Donoghue AJ, Jin Y, Knudsen GM, Perera NC, Jenne DE, Murphy JE, Craik CS, Hermiston TW. PMID: 24073241; PMCID: PMC3779220.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    133. Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica. PLoS Negl Trop Dis. 2013; 7(7):e2269. Corvo I, O'Donoghue AJ, Pastro L, Pi-Denis N, Eroy-Reveles A, Roche L, McKerrow JH, Dalton JP, Craik CS, Caffrey CR, Tort JF. PMID: 23875031; PMCID: PMC3708847.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    134. Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis. J Biol Chem. 2013 May 03; 288(18):12489-99. Small JL, O'Donoghue AJ, Boritsch EC, Tsodikov OV, Knudsen GM, Vandal O, Craik CS, Ehrt S. PMID: 23504313; PMCID: PMC3642297.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    135. Detection and Quantification of Endoprotease Activity Using a Coomassie Dye-Binding Assay. Laboratory Protocols in Fungal Biology. 2012; 309-313. Anthony J. O'Donoghue, Cathal Mahon. View Publication.
    136. Global identification of peptidase specificity by multiplex substrate profiling. Nat Methods. 2012 Nov; 9(11):1095-100. O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS. PMID: 23023596; PMCID: PMC3707110.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    137. Characterization of gut-associated cathepsin D hemoglobinase from tick Ixodes ricinus (IrCD1). J Biol Chem. 2012 Jun 15; 287(25):21152-63. Sojka D, Franta Z, Frantová H, Bartosová P, Horn M, Váchová J, O'Donoghue AJ, Eroy-Reveles AA, Craik CS, Knudsen GM, Caffrey CR, McKerrow JH, Mares M, Kopácek P. PMID: 22539347; PMCID: PMC3375538.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    138. Global landscape of HIV-human protein complexes. Nature. 2011 Dec 21; 481(7381):365-70. Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ. PMID: 22190034; PMCID: PMC3310911.
      View in: PubMed   Mentions: 459     Fields:    Translation:HumansCells
    139. Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii. Microbiology (Reading). 2009 Nov; 155(Pt 11):3673-3682. Mahon CS, O'Donoghue AJ, Goetz DH, Murray PG, Craik CS, Tuohy MG. PMID: 19556294; PMCID: PMC2888130.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    140. A parasite cysteine protease is key to host protein degradation and iron acquisition. J Biol Chem. 2008 Oct 24; 283(43):28934-43. O'Brien TC, Mackey ZB, Fetter RD, Choe Y, O'Donoghue AJ, Zhou M, Craik CS, Caffrey CR, McKerrow JH. PMID: 18701454; PMCID: PMC2570886.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    141. Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii. J Biol Chem. 2008 Oct 24; 283(43):29186-95. O'Donoghue AJ, Mahon CS, Goetz DH, O'Malley JM, Gallagher DM, Zhou M, Murray PG, Craik CS, Tuohy MG. PMID: 18687686; PMCID: PMC2570871.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    142. Cloning and characterization of osteoclast precursors from the RAW264.7 cell line. In Vitro Cell Dev Biol Anim. 2006 Jul-Aug; 42(7):182-8. Cuetara BL, Crotti TN, O'Donoghue AJ, McHugh KP. PMID: 16948499; PMCID: PMC2883882.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
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