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Jesse Jokerst

Title(s)Associate Adjunct Professor, Radiology
SchoolAcademic Aff
Phone858-246-0896
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    Collapse Research 
    Collapse Research Activities and Funding
    Non-Invasive Detection and Staging of Decubitus and Diabetic Ulcers
    NIH/NIA R21AG065776Dec 15, 2019 - Nov 30, 2021
    Role: Principal Investigator
    A Miniaturized Tool for Ultrasound Quantification of Periodontal Disease
    NIH/NIDCR R21DE029025Aug 2, 2019 - Jul 31, 2021
    Role: Principal Investigator
    MANTA ViewSizer 3011 Nanoparticle Characterization System
    NIH S10OD023555Aug 18, 2018 - Aug 17, 2019
    Role: Principal Investigator
    Therapeutic Drug Monitoring with a Wearable Ultrasound-based Sensor
    NIH/NHLBI DP2HL137187Sep 30, 2016 - Jun 30, 2021
    Role: Principal Investigator
    A Therapeutic Tool for Ultrasound-Guided Stem Cell Therapy
    NIH/NHLBI R00HL117048Jul 1, 2015 - Jun 30, 2018
    Role: Principal Investigator
    A Therapeutic Tool for ULtrasound-Guided Stem Cell Therapy
    NIH/NHLBI K99HL117048Dec 12, 2013 - Nov 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Jeevarathinam AS, Lemaster JE, Chen F, Zhao E, Jokerst J. Photoacoustic Imaging Quantifies Drug Release from Nanocarriers via Redox Chemistry of Dye-Labeled Cargo. Angew Chem Int Ed Engl. 2019 Dec 15. PMID: 31840357.
      View in: PubMed
    2. Kang J, Kim D, Wang J, Han Y, Zuidema JM, Hariri A, Park JH, Jokerst JV, Sailor MJ. Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles. Adv Mater. 2019 10; 31(41):e1905454. PMID: 31595594.
      View in: PubMed
    3. Xie Y, Wang J, Wang J, Hu Z, Hariri A, Tu N, Krug KA, Burkart MD, Gianneschi NC, Jokerst JV, Rinehart JD. Tuning the ultrasonic and photoacoustic response of polydopamine-stabilized perfluorocarbon contrast agents. J Mater Chem B. 2019 Aug 07; 7(31):4833-4842. PMID: 31389967.
      View in: PubMed
    4. Hariri A, Zhao E, Jeevarathinam AS, Lemaster J, Zhang J, Jokerst JV. Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system. Sci Rep. 2019 Aug 06; 9(1):11378. PMID: 31388020.
      View in: PubMed
    5. Hariri A, Chen F, Moore C, Jokerst JV. Noninvasive staging of pressure ulcers using photoacoustic imaging. Wound Repair Regen. 2019 09; 27(5):488-496. PMID: 31301258.
      View in: PubMed
    6. Miri Rostami SR, Mozaffarzadeh M, Ghaffari-Miab M, Hariri A, Jokerst J. GPU-accelerated Double-stage Delay-multiply-and-sum Algorithm for Fast Photoacoustic Tomography Using LED Excitation and Linear Arrays. Ultrason Imaging. 2019 Sep; 41(5):301-316. PMID: 31322057.
      View in: PubMed
    7. Moore C, Chen F, Wang J, Jokerst JV. Listening for the therapeutic window: Advances in drug delivery utilizing photoacoustic imaging. Adv Drug Deliv Rev. 2019 Apr; 144:78-89. PMID: 31295522.
      View in: PubMed
    8. Chen F, Zhao ER, Hableel G, Hu T, Kim T, Li J, Gonzalez-Pech NI, Cheng DJ, Lemaster JE, Xie Y, Grassian VH, Sen GL, Jokerst JV. Increasing the Efficacy of Stem Cell Therapy via Triple-Function Inorganic Nanoparticles. ACS Nano. 2019 Jun 25; 13(6):6605-6617. PMID: 31188564.
      View in: PubMed
    9. Moore C, Jokerst JV. Strategies for Image-Guided Therapy, Surgery, and Drug Delivery Using Photoacoustic Imaging. Theranostics. 2019; 9(6):1550-1571. PMID: 31037123.
      View in: PubMed
    10. Naveau A, Shinmyouzu K, Moore C, Avivi-Arber L, Jokerst J, Koka S. Etiology and Measurement of Peri-Implant Crestal Bone Loss (CBL). J Clin Med. 2019 Feb 01; 8(2). PMID: 30717189.
      View in: PubMed
    11. Jeevarathinam AS, Pai N, Huang K, Hariri A, Wang J, Bai Y, Wang L, Hancock T, Keys S, Penny W, Jokerst JV. A cellulose-based photoacoustic sensor to measure heparin concentration and activity in human blood samples. Biosens Bioelectron. 2019 Feb 01; 126:831-837. PMID: 30602265.
      View in: PubMed
    12. Moore C, Bai Y, Hariri A, Sanchez JB, Lin CY, Koka S, Sedghizadeh P, Chen C, Jokerst JV. Photoacoustic imaging for monitoring periodontal health: A first human study. Photoacoustics. 2018 Dec; 12:67-74. PMID: 30450281.
      View in: PubMed
    13. Wang J, Jeevarathinam AS, Humphries K, Jhunjhunwala A, Chen F, Hariri A, Miller BR, Jokerst JV. A Mechanistic Investigation of Methylene Blue and Heparin Interactions and Their Photoacoustic Enhancement. Bioconjug Chem. 2018 11 21; 29(11):3768-3775. PMID: 30281976.
      View in: PubMed
    14. Mozaffarzadeh M, Hariri A, Moore C, Jokerst JV. The double-stage delay-multiply-and-sum image reconstruction method improves imaging quality in a LED-based photoacoustic array scanner. Photoacoustics. 2018 Dec; 12:22-29. PMID: 30294542.
      View in: PubMed
    15. Dhong C, Edmunds SJ, Ramírez J, Kayser LV, Chen F, Jokerst JV, Lipomi DJ. Optics-Free, Non-Contact Measurements of Fluids, Bubbles, and Particles in Microchannels Using Metallic Nano-Islands on Graphene. Nano Lett. 2018 08 08; 18(8):5306-5311. PMID: 30024767.
      View in: PubMed
    16. Chen F, Li G, Zhao ER, Li J, Hableel G, Lemaster JE, Bai Y, Sen GL, Jokerst JV. Cellular toxicity of silicon carbide nanomaterials as a function of morphology. Biomaterials. 2018 10; 179:60-70. PMID: 29980075.
      View in: PubMed
    17. Kang J, Kim D, Wang J, Han Y, Zuidema JM, Hariri A, Park JH, Jokerst JV, Sailor MJ. Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles. Adv Mater. 2018 Jul; 30(27):e1800512. PMID: 29782671.
      View in: PubMed
    18. Kim T, Zhang Q, Li J, Zhang L, Jokerst JV. A Gold/Silver Hybrid Nanoparticle for Treatment and Photoacoustic Imaging of Bacterial Infection. ACS Nano. 2018 06 26; 12(6):5615-5625. PMID: 29746090.
      View in: PubMed
    19. Pohling C, Campbell JL, Larson TA, Van de Sompel D, Levi J, Bachmann MH, Bohndiek SE, Jokerst JV, Gambhir SS. Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging. Small. 2018 05; 14(19):e1703683. PMID: 29635739.
      View in: PubMed
    20. Jokerst JV, Cauwenberghs N, Kuznetsova T, Haddad F, Sweeney T, Hou J, Rosenberg-Hasson Y, Zhao E, Schutt R, Bolli R, Traverse JH, Pepine CJ, Henry TD, Schulman IH, Moyé L, Taylor DA, Yang PC. Author Correction: Circulating Biomarkers to Identify Responders in Cardiac Cell therapy. Sci Rep. 2018 Mar 06; 8(1):4257. PMID: 29511207.
      View in: PubMed
    21. Hariri A, Wang J, Kim Y, Jhunjhunwala A, Chao DL, Jokerst JV. In vivo photoacoustic imaging of chorioretinal oxygen gradients. J Biomed Opt. 2018 03; 23(3):1-8. PMID: 29524321.
      View in: PubMed
    22. Chen F, Hableel G, Zhao ER, Jokerst JV. Multifunctional nanomedicine with silica: Role of silica in nanoparticles for theranostic, imaging, and drug monitoring. J Colloid Interface Sci. 2018 Jul 01; 521:261-279. PMID: 29510868.
      View in: PubMed
    23. Wang J, Lin CY, Moore C, Jhunjhunwala A, Jokerst JV. Switchable Photoacoustic Intensity of Methylene Blue via Sodium Dodecyl Sulfate Micellization. Langmuir. 2018 01 09; 34(1):359-365. PMID: 29232146.
      View in: PubMed
    24. Hariri A, Lemaster J, Wang J, Jeevarathinam AS, Chao DL, Jokerst JV. The characterization of an economic and portable LED-based photoacoustic imaging system to facilitate molecular imaging. Photoacoustics. 2018 Mar; 9:10-20. PMID: 29234601.
      View in: PubMed
    25. Liu F, Vermesh O, Mani V, Ge TJ, Madsen SJ, Sabour A, Hsu EC, Gowrishankar G, Kanada M, Jokerst JV, Sierra RG, Chang E, Lau K, Sridhar K, Bermudez A, Pitteri SJ, Stoyanova T, Sinclair R, Nair VS, Gambhir SS, Demirci U. The Exosome Total Isolation Chip. ACS Nano. 2017 11 28; 11(11):10712-10723. PMID: 29090896.
      View in: PubMed
    26. Miao Q, Xie C, Zhen X, Lyu Y, Duan H, Liu X, Jokerst JV, Pu K. Molecular afterglow imaging with bright, biodegradable polymer nanoparticles. Nat Biotechnol. 2017 Nov; 35(11):1102-1110. PMID: 29035373.
      View in: PubMed
    27. Lin CY, Chen F, Hariri A, Chen CJ, Wilder-Smith P, Takesh T, Jokerst JV. Photoacoustic Imaging for Noninvasive Periodontal Probing Depth Measurements. J Dent Res. 2018 Jan; 97(1):23-30. PMID: 28880116.
      View in: PubMed
    28. Kim T, Lemaster JE, Chen F, Li J, Jokerst JV. Photoacoustic Imaging of Human Mesenchymal Stem Cells Labeled with Prussian Blue-Poly(l-lysine) Nanocomplexes. ACS Nano. 2017 09 26; 11(9):9022-9032. PMID: 28759195.
      View in: PubMed
    29. He S, Johnson NJJ, Nguyen Huu VA, Cory E, Huang Y, Sah RL, Jokerst JV, Almutairi A. Simultaneous Enhancement of Photoluminescence, MRI Relaxivity, and CT Contrast by Tuning the Interfacial Layer of Lanthanide Heteroepitaxial Nanoparticles. Nano Lett. 2017 08 09; 17(8):4873-4880. PMID: 28657755.
      View in: PubMed
    30. Jokerst JV, Cauwenberghs N, Kuznetsova T, Haddad F, Sweeney T, Hou J, Rosenberg-Hasson Y, Zhao E, Schutt R, Bolli R, Traverse JH, Pepine CJ, Henry TD, Schulman IH, Moyé L, Taylor DA, Yang PC. Circulating Biomarkers to Identify Responders in Cardiac Cell therapy. Sci Rep. 2017 06 30; 7(1):4419. PMID: 28667255.
      View in: PubMed
    31. Chen F, Zhao E, Kim T, Wang J, Hableel G, Reardon PJT, Ananthakrishna SJ, Wang T, Arconada-Alvarez S, Knowles JC, Jokerst JV. Organosilica Nanoparticles with an Intrinsic Secondary Amine: An Efficient and Reusable Adsorbent for Dyes. ACS Appl Mater Interfaces. 2017 May 10; 9(18):15566-15576. PMID: 28422482.
      View in: PubMed
    32. Arconada-Alvarez SJ, Lemaster JE, Wang J, Jokerst JV. The development and characterization of a novel yet simple 3D printed tool to facilitate phantom imaging of photoacoustic contrast agents. Photoacoustics. 2017 Mar; 5:17-24. PMID: 28239554.
      View in: PubMed
    33. Chen F, Ma M, Wang J, Wang F, Chern SX, Zhao ER, Jhunjhunwala A, Darmadi S, Chen H, Jokerst JV. Exosome-like silica nanoparticles: a novel ultrasound contrast agent for stem cell imaging. Nanoscale. 2017 Jan 07; 9(1):402-411. PMID: 27924340.
      View in: PubMed
    34. Thakor AS, Jokerst JV, Ghanouni P, Campbell JL, Mittra E, Gambhir SS. Clinically Approved Nanoparticle Imaging Agents. J Nucl Med. 2016 Dec; 57(12):1833-1837. PMID: 27738007.
      View in: PubMed
    35. Wang J, Chen F, Arconada-Alvarez SJ, Hartanto J, Yap LP, Park R, Wang F, Vorobyova I, Dagliyan G, Conti PS, Jokerst JV. A Nanoscale Tool for Photoacoustic-Based Measurements of Clotting Time and Therapeutic Drug Monitoring of Heparin. Nano Lett. 2016 Oct 12; 16(10):6265-6271. PMID: 27668964.
      View in: PubMed
    36. Lemaster JE, Jokerst JV. What is new in nanoparticle-based photoacoustic imaging? Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 01; 9(1). PMID: 27038222.
      View in: PubMed
    37. Van de Sompel D, Sasportas LS, Jokerst JV, Gambhir SS. Comparison of Deconvolution Filters for Photoacoustic Tomography. PLoS One. 2016; 11(3):e0152597. PMID: 27031832.
      View in: PubMed
    38. Wang J, Jokerst JV. Stem Cell Imaging: Tools to Improve Cell Delivery and Viability. Stem Cells Int. 2016; 2016:9240652. PMID: 26880997.
      View in: PubMed
    39. Jokerst JV, Chen Z, Xu L, Nolley R, Chang E, Mitchell B, Brooks JD, Gambhir SS. A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. PLoS One. 2015; 10(9):e0139484. PMID: 26421725.
      View in: PubMed
    40. Bohndiek SE, Sasportas LS, Machtaler S, Jokerst JV, Hori S, Gambhir SS. Photoacoustic Tomography Detects Early Vessel Regression and Normalization During Ovarian Tumor Response to the Antiangiogenic Therapy Trebananib. J Nucl Med. 2015 Dec; 56(12):1942-7. PMID: 26315834.
      View in: PubMed
    41. Pu K, Mei J, Jokerst JV, Hong G, Antaris AL, Chattopadhyay N, Shuhendler AJ, Kurosawa T, Zhou Y, Gambhir SS, Bao Z, Rao J. Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging. Adv Mater. 2015 Sep 16; 27(35):5184-90. PMID: 26247171.
      View in: PubMed
    42. Ho IT, Sessler JL, Gambhir SS, Jokerst JV. Parts per billion detection of uranium with a porphyrinoid-containing nanoparticle and in vivo photoacoustic imaging. Analyst. 2015 Jun 07; 140(11):3731-7. PMID: 25854506.
      View in: PubMed
    43. Kempen PJ, Greasley S, Parker KA, Campbell JL, Chang HY, Jones JR, Sinclair R, Gambhir SS, Jokerst JV. Theranostic mesoporous silica nanoparticles biodegrade after pro-survival drug delivery and ultrasound/magnetic resonance imaging of stem cells. Theranostics. 2015; 5(6):631-42. PMID: 25825602.
      View in: PubMed
    44. Foroutan F, Jokerst JV, Gambhir SS, Vermesh O, Kim HW, Knowles JC. Sol-gel synthesis and electrospraying of biodegradable (P2O5)55-(CaO)30-(Na2O)15 glass nanospheres as a transient contrast agent for ultrasound stem cell imaging. ACS Nano. 2015 Feb 24; 9(2):1868-1877. PMID: 25625373.
      View in: PubMed
    45. Kempen PJ, Kircher MF, de la Zerda A, Zavaleta CL, Jokerst JV, Mellinghoff IK, Gambhir SS, Sinclair R. A correlative optical microscopy and scanning electron microscopy approach to locating nanoparticles in brain tumors. Micron. 2015 Jan; 68:70-76. PMID: 25464144.
      View in: PubMed
    46. Jokerst JV, Van de Sompel D, Bohndiek SE, Gambhir SS. Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice. Photoacoustics. 2014 Sep 01; 2(3):119-127. PMID: 25225633.
      View in: PubMed
    47. Jokerst JV. Bioimaging: sensed at the gut level. Nat Nanotechnol. 2014 Aug; 9(8):569-70. PMID: 25091444.
      View in: PubMed
    48. Cheng K, Kothapalli SR, Liu H, Koh AL, Jokerst JV, Jiang H, Yang M, Li J, Levi J, Wu JC, Gambhir SS, Cheng Z. Construction and validation of nano gold tripods for molecular imaging of living subjects. J Am Chem Soc. 2014 Mar 05; 136(9):3560-71. PMID: 24495038.
      View in: PubMed
    49. Pu K, Shuhendler AJ, Jokerst JV, Mei J, Gambhir SS, Bao Z, Rao J. Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice. Nat Nanotechnol. 2014 Mar; 9(3):233-9. PMID: 24463363.
      View in: PubMed
    50. Jokerst JV, Pohling C, Gambhir SS. Molecular imaging with surface-enhanced Raman spectroscopy nanoparticle reporters. MRS Bull. 2013 Aug; 38(8). PMID: 24293809.
      View in: PubMed
    51. Bohndiek SE, Wagadarikar A, Zavaleta CL, Van de Sompel D, Garai E, Jokerst JV, Yazdanfar S, Gambhir SS. A small animal Raman instrument for rapid, wide-area, spectroscopic imaging. Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30):12408-13. PMID: 23821752.
      View in: PubMed
    52. Jokerst JV, Khademi C, Gambhir SS. Intracellular aggregation of multimodal silica nanoparticles for ultrasound-guided stem cell implantation. Sci Transl Med. 2013 Mar 20; 5(177):177ra35. PMID: 23515077.
      View in: PubMed
    53. Jokerst JV, Cole AJ, Van de Sompel D, Gambhir SS. Gold nanorods for ovarian cancer detection with photoacoustic imaging and resection guidance via Raman imaging in living mice. ACS Nano. 2012 Nov 27; 6(11):10366-77. PMID: 23101432.
      View in: PubMed
    54. Jokerst JV, Thangaraj M, Kempen PJ, Sinclair R, Gambhir SS. Photoacoustic imaging of mesenchymal stem cells in living mice via silica-coated gold nanorods. ACS Nano. 2012 Jul 24; 6(7):5920-30. PMID: 22681633.
      View in: PubMed
    55. Kircher MF, de la Zerda A, Jokerst JV, Zavaleta CL, Kempen PJ, Mittra E, Pitter K, Huang R, Campos C, Habte F, Sinclair R, Brennan CW, Mellinghoff IK, Holland EC, Gambhir SS. A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle. Nat Med. 2012 Apr 15; 18(5):829-34. PMID: 22504484.
      View in: PubMed
    56. Jokerst JV, Gambhir SS. Molecular imaging with theranostic nanoparticles. Acc Chem Res. 2011 Oct 18; 44(10):1050-60. PMID: 21919457.
      View in: PubMed
    57. Thakor AS, Jokerst J, Zavaleta C, Massoud TF, Gambhir SS. Gold nanoparticles: a revival in precious metal administration to patients. Nano Lett. 2011 Oct 12; 11(10):4029-36. PMID: 21846107.
      View in: PubMed
    58. Jokerst JV, Lobovkina T, Zare RN, Gambhir SS. Nanoparticle PEGylation for imaging and therapy. Nanomedicine (Lond). 2011 Jun; 6(4):715-28. PMID: 21718180.
      View in: PubMed
    59. Jokerst JV, Miao Z, Zavaleta C, Cheng Z, Gambhir SS. Affibody-functionalized gold-silica nanoparticles for Raman molecular imaging of the epidermal growth factor receptor. Small. 2011 Mar 07; 7(5):625-33. PMID: 21302357.
      View in: PubMed
    60. Jokerst JV, Chou J, Camp JP, Wong J, Lennart A, Pollard AA, Floriano PN, Christodoulides N, Simmons GW, Zhou Y, Ali MF, McDevitt JT. Location of biomarkers and reagents within agarose beads of a programmable bio-nano-chip. Small. 2011 Mar 07; 7(5):613-24. PMID: 21290601.
      View in: PubMed
    61. Jokerst JV, Jacobson JW, Bhagwandin BD, Floriano PN, Christodoulides N, McDevitt JT. Programmable nano-bio-chip sensors: analytical meets clinical. Anal Chem. 2010 Mar 01; 82(5):1571-9. PMID: 20128622.
      View in: PubMed
    62. Jokerst JV, McDevitt JT. Programmable nano-bio-chips: multifunctional clinical tools for use at the point-of-care. Nanomedicine (Lond). 2010 Jan; 5(1):143-55. PMID: 20025471.
      View in: PubMed
    63. Jokerst JV, Raamanathan A, Christodoulides N, Floriano PN, Pollard AA, Simmons GW, Wong J, Gage C, Furmaga WB, Redding SW, McDevitt JT. Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels. Biosens Bioelectron. 2009 Aug 15; 24(12):3622-9. PMID: 19576756.
      View in: PubMed
    64. Jokerst JV, Floriano PN, Christodoulides N, Simmons GW, McDevitt JT. Integration of semiconductor quantum dots into nano-bio-chip systems for enumeration of CD4+ T cell counts at the point-of-need. Lab Chip. 2008 Dec; 8(12):2079-90. PMID: 19023471.
      View in: PubMed
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