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Joshua Fierer

Photo of Joshua Fierer
Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Other Positions
    Title(s)Professor In Residence, Pathology

    Title(s)Professor


    Collapse Biography 
    Collapse education and training
    NYU School of Medicine, New York CityM.D.06/1963

    Collapse Research 
    Collapse research activities and funding
    37th Annual Meeting of the Society for Leukocyte Biology
    NIH R13AI062127Sep 30, 2004 - Sep 29, 2005
    Role: Principal Investigator
    Innate Immunity to Salmonella Infections
    NIH R01AI047884Mar 1, 2001 - Feb 28, 2008
    Role: Principal Investigator
    Combating Antibiotic Resistance Into the Next Generation (CARING)
    NIH T32AI007036Jul 1, 1976 - Jun 30, 2026
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development of a Mouse Model of Coccidioidomycosis Using an Inhalation Exposure System. J Fungi (Basel). 2025 Aug 19; 11(8). Erlich JR, Rodriguez P, Yau KPS, Tate M, Carlin AF, Fierer J, Kirkland TN, Hoffman HM, Beyhan S, Croker BA. PMID: 40863551; PMCID: PMC12387420.
      View in: PubMed   Mentions:
    2. Pleural Empyema: Etiology and Pathogenesis. Clin Infect Dis. 2024 Dec 17; 79(6):1533. Musher DM, Gorbach S, Fierer J. PMID: 38446994.
      View in: PubMed   Mentions: 1     Fields:    
    3. The Host Response to Coccidioidomycosis. J Fungi (Basel). 2024 Feb 25; 10(3). Kirkland TN, Hung CY, Shubitz LF, Beyhan S, Fierer J. PMID: 38535182; PMCID: PMC10971205.
      View in: PubMed   Mentions:
    4. Immunogenetics associated with severe coccidioidomycosis. JCI Insight. 2022 11 22; 7(22). Hsu AP, Korzeniowska A, Aguilar CC, Gu J, Karlins E, Oler AJ, Chen G, Reynoso GV, Davis J, Chaput A, Peng T, Sun L, Lack JB, Bays DJ, Stewart ER, Waldman SE, Powell DA, Donovan FM, Desai JV, Pouladi N, Long Priel DA, Yamanaka D, Rosenzweig SD, Niemela JE, Stoddard J, Freeman AF, Zerbe CS, Kuhns DB, Lussier YA, Olivier KN, Boucher RC, Hickman HD, Frelinger J, Fierer J, Shubitz LF, Leto TL, Thompson GR, Galgiani JN, Lionakis MS, Holland SM. PMID: 36166305; PMCID: PMC9746810.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    5. Controversies in the Management of Central Nervous System Coccidioidomycosis. Clin Infect Dis. 2022 09 10; 75(4):555-559. Thompson GR, Ampel NM, Blair JE, Donovan F, Fierer J, Galgiani JN, Heidari A, Johnson R, Shatsky SA, Uchiyama CM, Stevens DA. PMID: 35717645.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    6. Invasive Non-typhoidal Salmonella (iNTS) Infections. Clin Infect Dis. 2022 09 10; 75(4):732-738. Fierer J. PMID: 35041743.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    7. Coccidioides Species: A Review of Basic Research: 2022. J Fungi (Basel). 2022 Aug 16; 8(8). Kirkland TN, Stevens DA, Hung CY, Beyhan S, Taylor JW, Shubitz LF, Duttke SH, Heidari A, Johnson RH, Deresinski SC, Lauer A, Fierer J. PMID: 36012847; PMCID: PMC9409882.
      View in: PubMed   Mentions: 10  
    8. Antimicrobial-Resistant Shigella spp. in San Diego, California, USA, 2017-2020. Emerg Infect Dis. 2022 06; 28(6):1110-1116. Gaufin T, Blumenthal J, Ramirez-Sanchez C, Mehta S, Pride DT, Fierer J, Jenks JD. PMID: 35608550; PMCID: PMC9155871.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Decoding Transcription Regulatory Mechanisms Associated with Coccidioides immitis Phase Transition Using Total RNA. mSystems. 2022 02 22; 7(1):e0140421. Duttke SH, Beyhan S, Singh R, Neal S, Viriyakosol S, Fierer J, Kirkland TN, Stajich JE, Benner C, Carlin AF. PMID: 35076277; PMCID: PMC8788335.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    10. Transcriptional Analysis of Coccidioides immitis Mycelia and Spherules by RNA Sequencing. J Fungi (Basel). 2021 May 07; 7(5). Carlin AF, Beyhan S, Peña JF, Stajich JE, Viriyakosol S, Fierer J, Kirkland TN. PMID: 34067070; PMCID: PMC8150946.
      View in: PubMed   Mentions: 12  
    11. One Small Step. Clin Infect Dis. 2021 03 15; 72(6):976-978. Fierer J. PMID: 32108221.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Interleukin-8 Receptor 2 (IL-8R2)-Deficient Mice Are More Resistant to Pulmonary Coccidioidomycosis than Control Mice. Infect Immun. 2020 12 15; 89(1). Carlin AF, Viriyakosol S, Okamoto S, Walls L, Fierer J. PMID: 33106296; PMCID: PMC7927936.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    13. Innate Immune Receptors and Defense Against Primary Pathogenic Fungi. Vaccines (Basel). 2020 Jun 13; 8(2). Kirkland TN, Fierer J. PMID: 32545735; PMCID: PMC7350247.
      View in: PubMed   Mentions: 14  
    14. Ethambutol-resistant Mycobacterium kansasii cervical lymphadenitis in an immunocompetent adult patient: A case report and literature review. J Clin Tuberc Other Mycobact Dis. 2020 Feb; 18:100137. Asensi V, Palacios JJ, Rivas-Carmenado M, Suárez-Zarracina T, Garcia-Carus E, Fernández LM, Torres HE, Fierer J, Carton JA. PMID: 31890900; PMCID: PMC6926166.
      View in: PubMed   Mentions:
    15. Invasive endemic fungi of the Western Hemisphere. Virulence. 2019 12; 10(1):832-834. Fierer J. PMID: 31578099; PMCID: PMC6779374.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    16. The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population. PLoS One. 2019; 14(10):e0220022. Pérez-Is L, Ocaña MG, Montes AH, Carton JA, Álvarez V, Meana Á, Fierer J, Valle-Garay E, Asensi V. PMID: 31647805; PMCID: PMC6812796.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    17. A 37-Year-Old Man With Pleuritic Chest Pain. Chest. 2019 07; 156(1):e15-e21. Galant-Swafford J, Light M, Onaitis MW, Rawlings SA, Fierer J, Landsberg JW. PMID: 31279380; PMCID: PMC6904853.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    18. A case of inguinal lymphogranuloma venereum imitating malignancy on CT imaging. Radiol Case Rep. 2019 May; 14(5):581-583. Promer K, Pillay A, Chi KH, Vahdat N, Katz SS, Chen CY, Fierer J. PMID: 30891106; PMCID: PMC6406045.
      View in: PubMed   Mentions:
    19. A review of innate and adaptive immunity to coccidioidomycosis. Med Mycol. 2019 Feb 01; 57(Supplement_1):S85-S92. Hung CY, Hsu AP, Holland SM, Fierer J. PMID: 30690602; PMCID: PMC6347076.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    20. APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia. Antimicrob Agents Chemother. 2019 02; 63(2). Viriyakosol S, Kapoor M, Okamoto S, Covel J, Soltow QA, Trzoss M, Shaw KJ, Fierer J. PMID: 30455238; PMCID: PMC6355600.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    21. Myeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis. Infect Immun. 2018 06; 86(6). Viriyakosol S, Walls L, Okamoto S, Raz E, Williams DL, Fierer J. PMID: 29610256; PMCID: PMC5964525.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Actinotignum schaalii Infection: A Clandestine Cause of Sterile Pyuria? Open Forum Infect Dis. 2018 Feb; 5(2):ofy015. Horton LE, Mehta SR, Aganovic L, Fierer J. PMID: 29450211; PMCID: PMC5808804.
      View in: PubMed   Mentions: 8  
    23. Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies. Int J Antimicrob Agents. 2018 Mar; 51(3):468-478. Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V. PMID: 29337066; PMCID: PMC5860678.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    24. Coccidioides immitis and posadasii; A review of their biology, genomics, pathogenesis, and host immunity. Virulence. 2018; 9(1):1426-1435. Kirkland TN, Fierer J. PMID: 30179067; PMCID: PMC6141143.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    25. Successful treatment of Aureobasidium pullulans central catheter-related fungemia and septic pulmonary emboli. IDCases. 2017; 10:65-67. Mehta SR, Johns S, Stark P, Fierer J. PMID: 28951848; PMCID: PMC5607119.
      View in: PubMed   Mentions: 6  
    26. Gordonia sternal wound infection treated with ceftaroline: case report and literature review. JMM Case Rep. 2017 Sep; 4(9):e005113. Akrami K, Coletta J, Mehta S, Fierer J. PMID: 29114395; PMCID: PMC5643002.
      View in: PubMed   Mentions: 5  
    27. Bacteremia and Skin Infections in Four Patients Caused by Helicobacter-Like Organisms. Open Forum Infect Dis. 2017; 4(3):ofx074. Pérez-Santiago J, Ramirez-Gaona M, Holm-Kennedy R, Smith DM, Fierer J. PMID: 31338379; PMCID: PMC6636245.
      View in: PubMed   Mentions:
    28. Comparison of the BD MAX MRSA XT to the Cepheid™ Xpert® MRSA assay for the molecular detection of methicillin-resistant Staphylococcus aureus from nasal swabs. Diagn Microbiol Infect Dis. 2017 Apr; 87(4):308-310. Mehta SR, Estrada J, Ybarra J, Fierer J. PMID: 28094151.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    29. La Tour's hypovitaminosis in the peasants' swollen eyelids and deformed nails. Br J Gen Pract. 2016 Dec; 66(653):618. Asensi V, Fierer J. PMID: 27884902; PMCID: PMC5198662.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli. Open Forum Infect Dis. 2016 Apr; 3(2):ofw079. Carter CC, Fierer J, Chiu WW, Looney DJ, Strain M, Mehta SR. PMID: 27419156; PMCID: PMC4943565.
      View in: PubMed   Mentions: 13  
    31. Vertebral Osteomyelitis Guidelines. Clin Infect Dis. 2016 Apr 01; 62(7):953-4. Fierer J. PMID: 26743096.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Butyricimonas virosa bacteraemia identified by MALDI-TOF. New Microbes New Infect. 2015 Nov; 8:127. Mehta SR, Estrada J, Basallo C, Farala A, Fierer J. PMID: 26693282; PMCID: PMC4660225.
      View in: PubMed   Mentions: 3  
    33. Rapid Identification of Rectal Multidrug-resistant Escherichia coli Before Transrectal Prostate Biopsy. Urology. 2015 Dec; 86(6):1200-5. Tchesnokova VL, Ottley LL, Sakamoto K, Fierer J, Sokurenko E, Liss MA. PMID: 26299464; PMCID: PMC4698053.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    34. Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. J Infect Dis. 2015 Jul 01; 212(1):128-36. Marchelletta RR, Gareau MG, Okamoto S, Guiney DG, Barrett KE, Fierer J. PMID: 25538271; PMCID: PMC4542593.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    35. Clinical and microbiological determinants of infection after transrectal prostate biopsy. Clin Infect Dis. 2015 Apr 01; 60(7):979-87. Liss MA, Johnson JR, Porter SB, Johnston B, Clabots C, Gillis K, Nseyo U, Holden M, Sakamoto K, Fierer J. PMID: 25516194.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    36. Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy. J Urol. 2014 Dec; 192(6):1673-8. Liss MA, Taylor SA, Batura D, Steensels D, Chayakulkeeree M, Soenens C, Rao GG, Dash A, Park S, Patel N, Woo J, McDonald M, Nseyo U, Banapour P, Unterberg S, Ahlering TE, Van Poppel H, Sakamoto K, Fierer J, Black PC. PMID: 24928266.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    37. Neither dectin-2 nor the mannose receptor is required for resistance to Coccidioides immitis in mice. Infect Immun. 2014 Mar; 82(3):1147-56. Viriyakosol S, Jimenez Mdel P, Saijo S, Fierer J. PMID: 24379281; PMCID: PMC3957980.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    38. Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis. Gastroenterology. 2013 Dec; 145(6):1358-1368.e1-4. Marchelletta RR, Gareau MG, McCole DF, Okamoto S, Roel E, Klinkenberg R, Guiney DG, Fierer J, Barrett KE. PMID: 24001788; PMCID: PMC3899031.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    39. Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature. BMC Microbiol. 2013 May 28; 13:121. Viriyakosol S, Singhania A, Fierer J, Goldberg J, Kirkland TN, Woelk CH. PMID: 23714098; PMCID: PMC3693894.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    40. tPA Alu (I/D) polymorphism associates with bacterial osteomyelitis. J Infect Dis. 2013 Jul 15; 208(2):218-23. Valle-Garay E, Montes AH, Corte JR, Meana A, Fierer J, Asensi V. PMID: 23570848.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    41. Dosing rifampin. Clin Infect Dis. 2013 Jul; 57(1):161. Fierer J. PMID: 23537908.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Dectin-1 is required for resistance to coccidioidomycosis in mice. mBio. 2013 Feb 05; 4(1):e00597-12. Viriyakosol S, Jimenez Mdel P, Gurney MA, Ashbaugh ME, Fierer J. PMID: 23386437; PMCID: PMC3562125.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    43. Group B Streptococcus CovR regulation modulates host immune signalling pathways to promote vaginal colonization. Cell Microbiol. 2013 Jul; 15(7):1154-67. Patras KA, Wang NY, Fletcher EM, Cavaco CK, Jimenez A, Garg M, Fierer J, Sheen TR, Rajagopal L, Doran KS. PMID: 23298320; PMCID: PMC3657335.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    44. Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection. Clin Infect Dis. 2013 Apr; 56(7):1038-43. Fierer DS, Dieterich DT, Fiel MI, Branch AD, Marks KM, Fusco DN, Hsu R, Smith DM, Fierer J. PMID: 23264364; PMCID: PMC3588118.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    45. Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection. BMC Microbiol. 2012 Sep 24; 12:218. Woelk CH, Zhang JX, Walls L, Viriyakosol S, Singhania A, Kirkland TN, Fierer J. PMID: 23006927; PMCID: PMC3528620.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    46. The use of ceftaroline fosamil in methicillin-resistant Staphylococcus aureus endocarditis and deep-seated MRSA infections: a retrospective case series of 10 patients. J Infect Chemother. 2013 Feb; 19(1):42-9. Lin JC, Aung G, Thomas A, Jahng M, Johns S, Fierer J. PMID: 22797874.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    47. Diarrhea and colitis in mice require the Salmonella pathogenicity island 2-encoded secretion function but not SifA or Spv effectors. Infect Immun. 2012 Oct; 80(10):3360-70. Fierer J, Okamoto S, Banerjee A, Guiney DG. PMID: 22778101; PMCID: PMC3457546.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    48. Hypercalcemia in disseminated coccidioidomycosis: expression of parathyroid hormone-related peptide is characteristic of granulomatous inflammation. Clin Infect Dis. 2012 Oct; 55(7):e61-6. Fierer J, Burton DW, Haghighi P, Deftos LJ. PMID: 22670039.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    49. Biofilm formation and Klebsiella pneumoniae liver abscess: true, true and unrelated? Virulence. 2012 May 01; 3(3):241-2. Fierer J. PMID: 22561156; PMCID: PMC3442835.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    50. Rectal cultures before transrectal ultrasound-guided prostate biopsy reduce post-prostatic biopsy infection rates. Urology. 2012 Mar; 79(3):556-61. Duplessis CA, Bavaro M, Simons MP, Marguet C, Santomauro M, Auge B, Collard DA, Fierer J, Lesperance J. PMID: 22386395.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    51. Recurring Klebsiella pneumoniae pyogenic liver abscesses in a resident of San Diego, California, due to a K1 strain carrying the virulence plasmid. J Clin Microbiol. 2011 Dec; 49(12):4371-3. Fierer J, Walls L, Chu P. PMID: 21998428; PMCID: PMC3232960.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    52. Improving reverse vaccinology with a machine learning approach. Vaccine. 2011 Oct 19; 29(45):8156-64. Bowman BN, McAdam PR, Vivona S, Zhang JX, Luong T, Belew RK, Sahota H, Guiney D, Valafar F, Fierer J, Woelk CH. PMID: 21864619.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    53. The Role of the spv Genes in Salmonella Pathogenesis. Front Microbiol. 2011; 2:129. Guiney DG, Fierer J. PMID: 21716657; PMCID: PMC3117207.
      View in: PubMed   Mentions: 114  
    54. The role of reactive oxygen intermediates in experimental coccidioidomycois in mice. BMC Microbiol. 2011 Apr 11; 11:71. Margolis DA, Viriyakosol S, Fierer J, Kirkland TN. PMID: 21481258; PMCID: PMC3088889.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    55. Re: "Community-acquired pneumonia". Pharos Alpha Omega Alpha Honor Med Soc. 2011; 74(4):52. Fierer J. PMID: 23256243.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    56. Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10638-43. Datta SK, Sabet M, Nguyen KP, Valdez PA, Gonzalez-Navajas JM, Islam S, Mihajlov I, Fierer J, Insel PA, Webster NJ, Guiney DG, Raz E. PMID: 20479237; PMCID: PMC2890829.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    57. Salmonella outcomes. J Infect Dis. 2008 Dec 01; 198(11):1724. Fierer J. PMID: 19000017.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    58. Secondary syphilis with ocular manifestations in older adults. Clin Infect Dis. 2008 Jun 15; 46(12):e142-5. Maves RC, Cachay ER, Young MA, Fierer J. PMID: 18462103.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    59. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell Immunol. 2008 Feb; 251(2):78-85. Wu CC, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson DA, Guiney DG, Corr M. PMID: 18495099; PMCID: PMC4012540.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCellsPHPublic Health
    60. A model of Salmonella colitis with features of diarrhea in SLC11A1 wild-type mice. PLoS One. 2008 Feb 13; 3(2):e1603. Woo H, Okamoto S, Guiney D, Gunn JS, Fierer J. PMID: 18270590; PMCID: PMC2225501.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    61. Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice. FEMS Immunol Med Microbiol. 2008 Mar; 52(2):194-201. Browne SH, Hasegawa P, Okamoto S, Fierer J, Guiney DG. PMID: 18248436.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    62. Complement C3d conjugation to anthrax protective antigen promotes a rapid, sustained, and protective antibody response. PLoS One. 2007 Oct 17; 2(10):e1044. Kolla RV, Chintalapati S, Sabet M, Santelli E, Liddington RC, David M, Fierer J, Guiney D, Rickert RC. PMID: 17940608; PMCID: PMC2001179.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    63. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell. 2007 Sep 07; 130(5):918-31. Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, Duyster J, Schmid RM, Eckmann L, Karin M. PMID: 17803913; PMCID: PMC2134986.
      View in: PubMed   Mentions: 337     Fields:    Translation:HumansAnimalsCells
    64. Pathogenicity of environmental isolates of V. cholerae in mice. Microbes Infect. 2007 Sep; 9(11):1351-8. Makri S, Purdy AE, Bartlett D, Fierer J. PMID: 17890125.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    65. A placebo-controlled, randomized, double-blinded study evaluating the safety of etanercept in patients with rheumatoid arthritis and concomitant comorbid diseases. Rheumatology (Oxford). 2007 Jul; 46(7):1122-5. Weisman MH, Paulus HE, Burch FX, Kivitz AJ, Fierer J, Dunn M, Kerr DR, Tsuji W, Baumgartner SW. PMID: 17470434.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    66. Medicare's Hospital Compare performance measures and mortality rates. JAMA. 2007 Apr 04; 297(13):1430; author reply 1431. Fierer J. PMID: 17405966.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Bax gene G(-248)A promoter polymorphism is associated with increased lifespan of the neutrophils of patients with osteomyelitis. Genet Med. 2007 Apr; 9(4):249-55. Ocaña MG, Valle-Garay E, Montes AH, Meana A, Cartón JA, Fierer J, Celada A, Asensi V. PMID: 17438390.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    68. The role of IL-10 in genetic susceptibility to coccidioidomycosis on mice. Ann N Y Acad Sci. 2007 Sep; 1111:236-44. Fierer J. PMID: 17363443.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    69. Gonococcal meningitis diagnosed by DNA amplification: case report and review of the literature. AIDS Patient Care STDS. 2007 Jan; 21(1):4-8. Cachay E, Mathews WC, Reed SL, Swancutt MA, Fierer J. PMID: 17263653.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    70. MDR-TB and HIV: the perfect storm? Am J Trop Med Hyg. 2006 Dec; 75(6):1025-6. Fierer J. PMID: 17172360.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    71. IL-10 and susceptibility to Coccidioides immitis infection. Trends Microbiol. 2006 Oct; 14(10):426-7. Fierer J. PMID: 16893649.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    72. Vaccination with irradiated Listeria induces protective T cell immunity. Immunity. 2006 Jul; 25(1):143-52. Datta SK, Okamoto S, Hayashi T, Shin SS, Mihajlov I, Fermin A, Guiney DG, Fierer J, Raz E. PMID: 16860763.
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    73. The NOS3 (27-bp repeat, intron 4) polymorphism is associated with susceptibility to osteomyelitis. Nitric Oxide. 2007 Feb; 16(1):44-53. Asensi V, Montes AH, Valle E, Ocaña MG, Astudillo A, Alvarez V, López-Anglada E, Solís A, Coto E, Meana A, Gonzalez P, Carton JA, Paz J, Fierer J, Celada A. PMID: 16889995.
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    74. High levels of interleukin-10 impair resistance to pulmonary coccidioidomycosis in mice in part through control of nitric oxide synthase 2 expression. Infect Immun. 2006 Jun; 74(6):3387-95. Jimenez Mdel P, Walls L, Fierer J. PMID: 16714569; PMCID: PMC1479230.
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    75. Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice. Infect Immun. 2006 Apr; 74(4):2498-502. Kim YR, Brinsmade SR, Yang Z, Escalante-Semerena J, Fierer J. PMID: 16552088; PMCID: PMC1418904.
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    76. Both CD4+ and CD8+ T cells can mediate vaccine-induced protection against Coccidioides immitis infection in mice. J Infect Dis. 2006 May 01; 193(9):1323-31. Fierer J, Waters C, Walls L. PMID: 16586371.
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    77. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun. 2005 Oct; 73(10):6771-81. Braff MH, Zaiou M, Fierer J, Nizet V, Gallo RL. PMID: 16177355; PMCID: PMC1230954.
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    78. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005 Jul 18; 202(2):209-15. Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. PMID: 16009720; PMCID: PMC2213009.
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    79. Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect Immun. 2005 Mar; 73(3):1553-60. Viriyakosol S, Fierer J, Brown GD, Kirkland TN. PMID: 15731053; PMCID: PMC1064940.
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    80. In vivo interleukin-6 protects neutrophils from apoptosis in osteomyelitis. Infect Immun. 2004 Jul; 72(7):3823-8. Asensi V, Valle E, Meana A, Fierer J, Celada A, Alvarez V, Paz J, Coto E, Carton JA, Maradona JA, Dieguez A, Sarasúa J, Ocaña MG, Arribas JM. PMID: 15213123; PMCID: PMC427428.
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    81. Treatment of candidal cholangitis with caspofungin therapy in a patient with a liver transplant: documentation of biliary excretion of caspofungin. Clin Infect Dis. 2004 Apr 01; 38(7):1040-1. Goicoechea M, Fierer J, Johns S. PMID: 15034841.
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    82. IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis. Am J Med Genet A. 2003 Jun 01; 119A(2):132-6. Asensi V, Alvarez V, Valle E, Meana A, Fierer J, Coto E, Carton JA, Maradona JA, Paz J, Dieguez MA, de la Fuente B, Moreno A, Rubio S, Tuya MJ, Sarasúa J, Llames S, Arribas JM. PMID: 12749050.
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    83. Interactions between inducible nitric oxide and other inflammatory mediators during Helicobacter pylori infection. Helicobacter. 2003; 8(5):495-502. Obonyo M, Guiney DG, Fierer J, Cole SP. PMID: 14535996.
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    84. Fatal Saccharomyces cerevisiae aortic graft infection. J Clin Microbiol. 2002 Jul; 40(7):2691-2. Smith D, Metzgar D, Wills C, Fierer J. PMID: 12089311; PMCID: PMC120603.
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    85. The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice. J Immunol. 2002 Jun 15; 168(12):6396-403. Fierer J, Swancutt MA, Heumann D, Golenbock D. PMID: 12055258.
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    86. Role of gamma interferon in Helicobacter pylori induction of inflammatory mediators during murine infection. Infect Immun. 2002 Jun; 70(6):3295-9. Obonyo M, Guiney DG, Harwood J, Fierer J, Cole SP. PMID: 12011029; PMCID: PMC127973.
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    87. Characterization of the spv locus in Salmonella enterica serovar Arizona. Infect Immun. 2002 Jun; 70(6):3290-4. Libby SJ, Lesnick M, Hasegawa P, Kurth M, Belcher C, Fierer J, Guiney DG. PMID: 12011028; PMCID: PMC127997.
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    88. Questioning CDC's "select agent" criteria. Science. 2002 Jan 04; 295(5552):43. Fierer J, Kirkland T. PMID: 11780643.
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    89. Polymorphonuclear leukocytes and innate immunity to Salmonella infections in mice. Microbes Infect. 2001 Nov-Dec; 3(14-15):1233-7. Fierer J. PMID: 11755411.
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    90. High-fat, high-cholesterol diet increases the incidence of gastritis in LDL receptor-negative mice. Arterioscler Thromb Vasc Biol. 2001 Jun; 21(6):991-6. Laurila A, Cole SP, Merat S, Obonyo M, Palinski W, Fierer J, Witztum JL. PMID: 11397709.
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    91. Diverse virulence traits underlying different clinical outcomes of Salmonella infection. J Clin Invest. 2001 Apr; 107(7):775-80. Fierer J, Guiney DG. PMID: 11285291; PMCID: PMC199580.
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    92. The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells. Mol Microbiol. 2001 Mar; 39(6):1464-70. Lesnick ML, Reiner NE, Fierer J, Guiney DG. PMID: 11260464.
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    93. Bursal sporotrichosis: case report and review. Clin Infect Dis. 2000 Aug; 31(2):615-6. Wang JP, Granlund KF, Bozzette SA, Botte MJ, Fierer J. PMID: 10987734.
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    94. Genetic evidence for the role of the Lv locus in early susceptibility but not IL-10 synthesis in experimental coccidioidomycosis in C57BL mice. J Infect Dis. 2000 Feb; 181(2):681-5. Fierer J, Walls L, Kirkland TN. PMID: 10669355.
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    95. Non-typhoid Salmonella: a review. Curr Clin Top Infect Dis. 2000; 20:134-57. Fierer J, Swancutt M. PMID: 10943522.
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    96. Genes influencing resistance to Coccidioides immitis and the interleukin-10 response map to chromosomes 4 and 6 in mice. Infect Immun. 1999 Jun; 67(6):2916-9. Fierer J, Walls L, Wright F, Kirkland TN. PMID: 10338499; PMCID: PMC96600.
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    97. Importance of interleukin-10 in genetic susceptibility of mice to Coccidioides immitis. Infect Immun. 1998 Sep; 66(9):4397-402. Fierer J, Walls L, Eckmann L, Yamamoto T, Kirkland TN. PMID: 9712793; PMCID: PMC108531.
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    98. The crucial role of polymorphonuclear leukocytes in resistance to Salmonella dublin infections in genetically susceptible and resistant mice. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7676-81. Vassiloyanakopoulos AP, Okamoto S, Fierer J. PMID: 9636209; PMCID: PMC22720.
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    99. D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14456-60. Eckmann L, Rudolf MT, Ptasznik A, Schultz C, Jiang T, Wolfson N, Tsien R, Fierer J, Shears SB, Kagnoff MF, Traynor-Kaplan AE. PMID: 9405634; PMCID: PMC25019.
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    100. Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. J Clin Invest. 1997 Jul 15; 100(2):296-309. Eckmann L, Stenson WF, Savidge TC, Lowe DC, Barrett KE, Fierer J, Smith JR, Kagnoff MF. PMID: 9218506; PMCID: PMC508192.
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    101. Role of alphabeta and gammadelta T cells in the host response to Salmonella infection as demonstrated in T-cell-receptor-deficient mice of defined Ity genotypes. Infect Immun. 1997 Jun; 65(6):2306-12. Weintraub BC, Eckmann L, Okamoto S, Hense M, Hedrick SM, Fierer J. PMID: 9169768; PMCID: PMC175320.
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    102. Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun. 1996 Nov; 64(11):4739-43. Chen CY, Eckmann L, Libby SJ, Fang FC, Okamoto S, Kagnoff MF, Fierer J, Guiney DG. PMID: 8890234; PMCID: PMC174440.
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    103. Coccidioidomycosis: a reemerging infectious disease. Emerg Infect Dis. 1996 Jul-Sep; 2(3):192-9. Kirkland TN, Fierer J. PMID: 8903229; PMCID: PMC2626789.
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    104. Genetically resistant (Ityr) and susceptible (Itys) congenic mouse strains show similar cytokine responses following infection with Salmonella dublin. J Immunol. 1996 Apr 15; 156(8):2894-900. Eckmann L, Fierer J, Kagnoff MF. PMID: 8609409.
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    105. Biology and clinical significance of virulence plasmids in Salmonella serovars. Clin Infect Dis. 1995 Oct; 21 Suppl 2:S146-51. Guiney DG, Fang FC, Krause M, Libby S, Buchmeier NA, Fierer J. PMID: 8845442.
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    106. A short biography of Abraham I. Braude. Clin Infect Dis. 1995 Oct; 21 Suppl 2:S143-5. Fierer J. PMID: 8845441.
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    107. Growth-phase regulation of plasmid virulence genes in Salmonella. Trends Microbiol. 1995 Jul; 3(7):275-9. Guiney DG, Libby S, Fang FC, Krause M, Fierer J. PMID: 7551642.
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    108. Intestinal epithelial cells as watchdogs for the natural immune system. Trends Microbiol. 1995 Mar; 3(3):118-20. Eckmann L, Kagnoff MF, Fierer J. PMID: 7773590.
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    109. Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis. NIAID Mycoses Study Group. Am J Med. 1995 Mar; 98(3):249-56. Catanzaro A, Galgiani JN, Levine BE, Sharkey-Mathis PK, Fierer J, Stevens DA, Chapman SW, Cloud G. PMID: 7872341.
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    110. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest. 1995 Jan; 95(1):55-65. Jung HC, Eckmann L, Yang SK, Panja A, Fierer J, Morzycka-Wroblewska E, Kagnoff MF. PMID: 7814646; PMCID: PMC295369.
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    111. Specificity of the complement resistance and cell association phenotypes encoded by the outer membrane protein genes rck from Salmonella typhimurium and ail from Yersinia enterocolitica. Infect Immun. 1994 Nov; 62(11):5183-6. Heffernan EJ, Wu L, Louie J, Okamoto S, Fierer J, Guiney DG. PMID: 7927803; PMCID: PMC303245.
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    112. Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells. Infect Immun. 1993 Dec; 61(12):5231-6. Fierer J, Eckmann L, Fang F, Pfeifer C, Finlay BB, Guiney D. PMID: 8225598; PMCID: PMC281306.
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    113. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun. 1993 Nov; 61(11):4569-74. Eckmann L, Kagnoff MF, Fierer J. PMID: 8406853; PMCID: PMC281206.
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    114. Liposome-incorporated ciprofloxacin in treatment of murine salmonellosis. Antimicrob Agents Chemother. 1993 Nov; 37(11):2293-7. Magallanes M, Dijkstra J, Fierer J. PMID: 8285608; PMCID: PMC192381.
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    115. IL-8 secreted by epithelial cells invaded by bacteria. Infect Agents Dis. 1993 Aug; 2(4):255-8. Fierer J, Eckmann L, Kagnoff M. PMID: 8173804.
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    116. Characterization of translation termination mutations in the spv operon of the Salmonella virulence plasmid pSDL2. J Bacteriol. 1992 Oct; 174(20):6418-23. Roudier C, Fierer J, Guiney DG. PMID: 1400193; PMCID: PMC207594.
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    117. Biliary concentrations of fluconazole in a patient with candidal cholecystitis: case report. Clin Infect Dis. 1992 Oct; 15(4):701-3. Bozzette SA, Gordon RL, Yen A, Rinaldi M, Ito MK, Fierer J. PMID: 1420685.
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    118. Mechanism of resistance to complement-mediated killing of bacteria encoded by the Salmonella typhimurium virulence plasmid gene rck. J Clin Invest. 1992 Sep; 90(3):953-64. Heffernan EJ, Reed S, Hackett J, Fierer J, Roudier C, Guiney D. PMID: 1522243; PMCID: PMC329951.
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    119. Salmonella typhimurium bacteremia: association with the virulence plasmid. J Infect Dis. 1992 Sep; 166(3):639-42. Fierer J, Krause M, Tauxe R, Guiney D. PMID: 1500749.
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    120. Intensive surveillance for infections in a three-year study of nursing home patients. Am J Epidemiol. 1992 Mar 15; 135(6):685-96. Jackson MM, Fierer J, Barrett-Connor E, Fraser D, Klauber MR, Hatch R, Burkhart B, Jones M. PMID: 1580245.
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    121. The acute-phase response protects mice from D-galactosamine sensitization to endotoxin and tumor necrosis factor-alpha. Hepatology. 1992 Jan; 15(1):122-9. Alcorn JM, Fierer J, Chojkier M. PMID: 1727788.
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    122. The Salmonella typhimurium virulence plasmid complement resistance gene rck is homologous to a family of virulence-related outer membrane protein genes, including pagC and ail. J Bacteriol. 1992 Jan; 174(1):84-91. Heffernan EJ, Harwood J, Fierer J, Guiney D. PMID: 1729227; PMCID: PMC205680.
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    123. Growth regulation of a Salmonella plasmid gene essential for virulence. J Bacteriol. 1991 Nov; 173(21):6783-9. Fang FC, Krause M, Roudier C, Fierer J, Guiney DG. PMID: 1938884; PMCID: PMC209028.
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    124. Type B Haemophilus influenzae-induced otitis media in the mouse. Laryngoscope. 1991 Jun; 101(6 Pt 1):648-56. Krekorian TD, Keithley EM, Fierer J, Harris JP. PMID: 2041446.
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    125. Human infection with Salmonella dublin. Medicine (Baltimore). 1991 May; 70(3):198-207. Fang FC, Fierer J. PMID: 2030643.
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    126. Genetic analysis of homology between the virulence plasmids of Salmonella dublin and Yersinia pseudotuberculosis. Infect Immun. 1991 May; 59(5):1860-3. Krause M, Harwood J, Fierer J, Guiney D. PMID: 1840573; PMCID: PMC257928.
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    127. Synergistic effect of human lysozyme plus ampicillin or beta-lysin on the killing of Listeria monocytogenes. J Infect Dis. 1991 Mar; 163(3):574-8. Asensi V, Fierer J. PMID: 1899873.
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    128. Molecular analysis of the virulence locus of the Salmonella dublin plasmid pSDL2. Mol Microbiol. 1991 Feb; 5(2):307-16. Krause M, Roudier C, Fierer J, Harwood J, Guiney D. PMID: 2041471.
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    129. Homologous DNA sequences on the virulence plasmids of pathogenic Yersinia and Salmonella dublin lane. Mol Microbiol. 1990 Jun; 4(6):905-11. Krause M, Fierer J, Guiney D. PMID: 2215215.
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    130. Correlation between the presence of sequences homologous to the vir region of Salmonella dublin plasmid pSDL2 and the virulence of twenty-two Salmonella serotypes in mice. Infect Immun. 1990 May; 58(5):1180-5. Roudier C, Krause M, Fierer J, Guiney DG. PMID: 2323813; PMCID: PMC258607.
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    131. Endotoxin-induced otitis media with effusion in the mouse. Immunohistochemical analysis. Acta Otolaryngol. 1990 Mar-Apr; 109(3-4):288-99. Krekorian TD, Keithley EM, Takahashi M, Fierer J, Harris JP. PMID: 2180249.
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    132. Fluconazole in the treatment of persistent coccidioidomycosis. Chest. 1990 Mar; 97(3):666-9. Catanzaro A, Fierer J, Friedman PJ. PMID: 2306969.
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    133. Successful treatment using gentamicin liposomes of Salmonella dublin infections in mice. Antimicrob Agents Chemother. 1990 Feb; 34(2):343-8. Fierer J, Hatlen L, Lin JP, Estrella D, Mihalko P, Yau-Young A. PMID: 2327780; PMCID: PMC171584.
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    134. Comparison of fluconazole and SDZ89-485 for therapy of experimental murine coccidioidomycosis. Antimicrob Agents Chemother. 1990 Jan; 34(1):13-6. Fierer J, Kirkland T, Finley F. PMID: 2327748; PMCID: PMC171511.
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    135. Active immunization with LD842, a plasmid-cured strain of Salmonella dublin, protects mice against group D and group B Salmonella infection. J Infect Dis. 1988 Aug; 158(2):460-3. Fierer J, Chikami G, Hatlen L, Heffernan EJ, Guiney D. PMID: 3403995.
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    136. Physical and genetic mapping of the Salmonella dublin virulence plasmid pSDL2. Relationship to plasmids from other Salmonella strains. J Clin Invest. 1988 May; 81(5):1341-7. Beninger PR, Chikami G, Tanabe K, Roudier C, Fierer J, Guiney DG. PMID: 2835396; PMCID: PMC442562.
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    137. Malassezia fungemia in neonates and adults: complication of hyperalimentation. Rev Infect Dis. 1987 Jul-Aug; 9(4):743-53. Dankner WM, Spector SA, Fierer J, Davis CE. PMID: 3125578.
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    138. The fetid foot: lower-extremity infections in patients with diabetes mellitus. Rev Infect Dis. 1979 Jan-Feb; 1(1):210-7. Fierer J, Daniel D, Davis C. PMID: 318225.
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    139. Induction of runt disease in newborn rats by prolonged antigenic stimulation with acellular tissue extracts. Transplantation. 1972 Mar; 13(3):332-5. Buda JA, Suciu-Foca N, Fierer JA, Geering G. PMID: 5021440.
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