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Victor Nizet

Title(s)Distinguished Professor, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0760
La Jolla CA 92093
Phone858-534-7408
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    Other Positions
    Title(s)Distinguished Professor, School of Pharmacy and Pharmaceutical Science


    Collapse Biography 
    Collapse Education and Training
    Reed College, Portland, ORBA05/1984Biology
    Stanford University, Stanford, CAMD05/1989Medicine
    Collapse Awards and Honors
    2019NIH/NAID Merit Award (R37)
    2017UCSD Chancellor's Associates Award for Excellence in Research in Science & Engineering
    2013UCSD Chancellor's Award for Excellence in Postdoctoral Scholar Mentoring
    2013Rady Children’s Hospital Award for Excellence in Research
    2012Elected to Fellowship in the American Academy of Microbiology
    2010Elected to Membership in the Association of American Physicians
    2008E. Mead Johnson Award for Research in Pediatrics, Society for Pediatric Research
    2008Stephen Silberstein Senior Fellow of the American Asthma Foundation
    2006Elected to Membership in the American Society for Clinical Investigation
    2006Elected to the American Pediatric Society
    2004Career Investigator Award, American Lung Association
    2004Established Investigator Award, American Heart Association
    2002Named the 39th Mallinckrodt Scholar by the Edward Mallinckrodt, Jr. Foundation
    2002Pediatric Infectious Diseases Society Young Investigator Award
    2002Elected to the Society for Pediatric Research
    2001UCSD Department of Pediatrics Commitment to Resident Education Award
    2000UCSD Department of Pediatrics Outstanding Faculty Teacher of the Year
    1993Sidney Farber Outstanding Houseofficer Award, Children’s Hospital, Boston
    1984Class of 1922 Award, Reed College, “Most Outstanding Senior Thesis”
    1984Phi Beta Kappa, Reed College

    Collapse Overview 
    Collapse Overview
    Victor Nizet is a Distinguished Professor and Vice Chair for Basic Research and Chief of the Division of Host-Microbe Systems & Therapeutics at the University of California, San Diego (UCSD), School of Medicine and Distinguished Professor at UCSD Skaggs School of Pharmacy & Pharmaceutical Sciences. Dr. Nizet is a graduate of Reed College, received his medical training at Stanford University School of Medicine, completed a Residency and Chief Residency in Pediatrics at Harvard University's Children's Hospital in Boston, Massachusetts, and a then a Fellowship in Pediatric Infectious Diseases at the University of Washington’s Children's Hospital in Seattle. Dr. Nizet is Faculty Lead for the UCSD Collaborative to Halt Antibiotic-Resistant Microbes (CHARM), a multidisciplinary research and educational program that debuted in Fall 2019. Dr. Nizet has authored over 440 peer-reviewed publications and has collaborated with several biotechnology interests in developing new antibiotic and immune-based therapies against drug-resistant pathogens. Details of his research program can be found on the laboratory website: http://nizetlab.ucsd.edu
    Collapse Interests

    Collapse Research 
    Collapse Research Activities and Funding
    Glycan-Lectin Receptor Regulation of Macrophage Maturation and Lung Innate Defenses in the Fetus and Newborn Infant
    NIH/NIAID R01AI142864Jul 17, 2019 - Jun 30, 2022
    Role: Co-Principal Investigator
    C3-Dependent Intracellular Killing in Innate Immunity and Bacterial Pathogenesis
    NIH/NIAID R01AI145325Mar 5, 2019 - Feb 29, 2024
    Role: Co-Principal Investigator
    2018 Streptococcal Biology Gordon Research Conference
    NIH/NIAID R13AI140636Jul 1, 2018 - Jun 30, 2019
    Role: Principal Investigator
    Broad recognition of group A Streptococcus M proteins
    NIH/NIAID R21AI140436May 18, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH/NICHD U54HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Glycoprotein Remodeling in the Vasculopathy and Coagulopathy of Sepsis
    NIH/NHLBI R01HL125352Sep 15, 2014 - May 31, 2019
    Role: Principal Investigator
    Analyzing a novel mechanism of action of bacterial cAMP producing toxins
    NIH/NIAID R01AI110713Feb 1, 2014 - Jan 31, 2019
    Role: Principal Investigator
    Mechanisms of the M protein in group A Streptococcus virulence
    NIH/NIAID R56AI096837Jul 1, 2011 - Jul 31, 2019
    Role: Co-Principal Investigator
    Glycan Modulation of Inflammatory Responses
    NIH P01HL107150Jul 1, 2011 - May 31, 2018
    Role: Co-Investigator
    Mechanisms of the M protein in group A Streptococcus virulence
    NIH/NIAID R01AI096837Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections
    NIH/NIAID R01AI093451Apr 5, 2011 - Mar 31, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Drug-Resistant Bacterial Infections
    NIH/NIAID R56AI090863Aug 2, 2010 - Jul 31, 2011
    Role: Principal Investigator
    GAS Switch from Colonizing Bacterium to Invasive Pathogen
    NIH/NIAID R01AI077780Sep 1, 2008 - Jan 31, 2020
    Role: Principal Investigator
    Sialic Acid O-Acetylation in GBS Pathogenesis &Immunity
    NIH/NICHD R01HD051796Apr 7, 2006 - Feb 28, 2012
    Role: Principal Investigator
    Molecular Analyses and Interventions for Biodefense and Emerging Pathogens
    NIH U54AI057153Sep 4, 2003 - Feb 28, 2014
    Role: Co-Investigator
    Cathelicidin in Skin Immunity
    NIH/NIAID R37AI052453Sep 15, 2002 - Feb 29, 2024
    Role: Co-Principal Investigator
    Cathelicidin in Skin Immunity
    NIH/NIAID R01AI052453Sep 15, 2002 - Nov 30, 2017
    Role: Principal Investigator
    SLS: Molecular Basis and Role in Invasive GAS Disease
    NIH/NIAID R01AI048694Apr 1, 2002 - Mar 31, 2007
    Role: Principal Investigator
    PENETRATION OF THE BLOOD BRAIN BARRIER IN GBS MENINGITIS
    NIH/NICHD R03HD037224Feb 1, 1999 - Jan 31, 2001
    Role: Principal Investigator
    MOLECULAR BASIS OF LUNG INJURY IN GBS PNEUMONIA
    NIH/NIAID K08AI001451Apr 1, 1997 - Mar 31, 2001
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interleukin (IL)-1ß and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy. Clin Infect Dis. 2020 Jun 10; 70(12):2634-2640. Volk CF, Burgdorf S, Edwardson G, Nizet V, Sakoulas G, Rose WE. PMID: 31365924.
      View in: PubMed   Mentions: 1     Fields:    
    2. Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. J Am Chem Soc. 2020 Jun 10. Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. PMID: 32479075.
      View in: PubMed   Mentions:    Fields:    
    3. All major cholesterol-dependent cytolysins use glycans as cellular receptors. Sci Adv. 2020 May; 6(21):eaaz4926. Shewell LK, Day CJ, Jen FE, Haselhorst T, Atack JM, Reijneveld JF, Everest-Dass A, James DBA, Boguslawski KM, Brouwer S, Gillen CM, Luo Z, Kobe B, Nizet V, von Itzstein M, Walker MJ, Paton AW, Paton JC, Torres VJ, Jennings MP. PMID: 32494740.
      View in: PubMed   Mentions:    Fields:    
    4. Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection. PLoS Genet. 2020 May; 16(5):e1008795. Kuang E, Okumura CYM, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. PMID: 32392217.
      View in: PubMed   Mentions:    Fields:    
    5. Tuning the Innate Immune Response to Cyclic Dinucleotides Using Atomic Mutagenesis. Chembiochem. 2020 Apr 28. Li Y, Fin A, Rovira A, Su Y, Dippel A, Valderrama A, Riestra A, Nizet V, Hammond MC, Tor Y. PMID: 32346955.
      View in: PubMed   Mentions:    Fields:    
    6. Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection. mSphere. 2020 Apr 22; 5(2). Patras KA, Coady A, Babu P, Shing SR, Ha AD, Rooholfada E, Brandt SL, Geriak M, Gallo RL, Nizet V. PMID: 32321824.
      View in: PubMed   Mentions:    Fields:    
    7. How Neutrophils Meet Their End. Trends Immunol. 2020 Apr 14. Lawrence SM, Corriden R, Nizet V. PMID: 32303452.
      View in: PubMed   Mentions:    Fields:    
    8. Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. mSystems. 2020 Mar 31; 5(2). Salazar MJ, Machado H, Dillon NA, Tsunemoto H, Szubin R, Dahesh S, Pogliano J, Sakoulas G, Palsson BO, Nizet V, Feist AM. PMID: 32234776.
      View in: PubMed   Mentions:
    9. Role of peribrachial fat as a key determinant of brachial artery dilatation for successful arteriovenous fistula maturation in hemodialysis patients. Sci Rep. 2020 Mar 02; 10(1):3841. Lee HS, Park MJ, Yoon SY, Joo N, Song YR, Kim HJ, Kim SG, Nizet V, Kim JK. PMID: 32123226.
      View in: PubMed   Mentions:    Fields:    
    10. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. 2020 03; 579(7797):123-129. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. PMID: 32103176.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    11. The Fungal Pathogen Candida albicans Promotes Bladder Colonization of Group B Streptococcus. Front Cell Infect Microbiol. 2019; 9:437. Shing SR, Ramos AR, Patras KA, Riestra AM, McCabe S, Nizet V, Coady A. PMID: 31998657.
      View in: PubMed   Mentions:    Fields:    
    12. Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program. Genes Dev. 2020 02 01; 34(3-4):149-165. Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C. PMID: 31919189.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Siglecs at the Host-Pathogen Interface. Adv Exp Med Biol. 2020; 1204:197-214. Chang YC, Nizet V. PMID: 32152948.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    14. Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media. Sci Data. 2019 12 17; 6(1):322. Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Nizet V, Palsson BO, Feist AM, Pogliano J. PMID: 31848353.
      View in: PubMed   Mentions:    Fields:    
    15. A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus. Nat Commun. 2019 12 16; 10(1):5726. Valderrama JA, Kulkarni SS, Nizet V, Bier E. PMID: 31844051.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages. J Innate Immun. 2019 Dec 05; 1-11. Tsai CM, Riestra AM, Ali SR, Fong JJ, Liu JZ, Hughes G, Varki A, Nizet V. PMID: 31805552.
      View in: PubMed   Mentions:    Fields:    
    17. Homophilic protein interactions facilitate bacterial aggregation and IgG-dependent complex formation by the Streptococcus canis M protein SCM. Virulence. 2019 12; 10(1):194-206. Nerlich A, Lapschies AM, Kohler TP, Cornax I, Eichhorn I, Goldmann O, Krienke P, Bergmann S, Nizet V, Hammerschmidt S, Rohde M, Fulde M. PMID: 30829556.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia. Clin Infect Dis. 2019 Nov 27. Ulloa ER, Singh KV, Geriak M, Haddad F, Murray BE, Nizet V, Sakoulas G. PMID: 31773134.
      View in: PubMed   Mentions:    Fields:    
    19. Erythrocyte-Coated Nanoparticles Block Cytotoxic Effects of Group B Streptococcus ß-Hemolysin/Cytolysin. Front Pediatr. 2019; 7:410. Koo J, Escajadillo T, Zhang L, Nizet V, Lawrence SM. PMID: 31737584.
      View in: PubMed   Mentions:
    20. Reply to Kalil et al., "Is Daptomycin plus Ceftaroline Associated with Better Clinical Outcomes than Standard of Care Monotherapy for Staphylococcus aureus Bacteremia?" Antimicrob Agents Chemother. 2019 11; 63(11). Sakoulas G, Geriak M, Haddad F, Rose W, LaPlante K, Zervos M, Kullar R, Nizet V. PMID: 31640978.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Strain-Specific Metabolic Requirements Revealed by a Defined Minimal Medium for Systems Analyses of Staphylococcus aureus. Appl Environ Microbiol. 2019 11 01; 85(21). Machado H, Weng LL, Dillon N, Seif Y, Holland M, Pekar JE, Monk JM, Nizet V, Palsson BO, Feist AM. PMID: 31471305.
      View in: PubMed   Mentions:    Fields:    
    22. Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis. Nat Commun. 2019 10 11; 10(1):4656. Toledo AG, Golden G, Campos AR, Cuello H, Sorrentino J, Lewis N, Varki N, Nizet V, Smith JW, Esko JD. PMID: 31604940.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia. Clin Infect Dis. 2019 09 13; 69(7):1232-1234. Walker MJ, Brouwer S, Forde BM, Worthing KA, McIntyre L, Sundac L, Maloney S, Roberts LW, Barnett TC, Richter J, Cork AJ, Irwin AD, You Y, Zhang J, Dougan G, Yuen KY, Nizet V, Beatson SA, Grimwood K, Davies MR. PMID: 30721938.
      View in: PubMed   Mentions: 1     Fields:    
    24. Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease. Front Microbiol. 2019; 10:1967. Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Gonzalez DJ, Olson J, Zengler K, Nizet V, Valderrama JA. PMID: 31507572.
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    25. PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. Elife. 2019 08 13; 8. Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. PMID: 31408005.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    26. Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens. EBioMedicine. 2019 Aug; 46:193-201. Dillon N, Holland M, Tsunemoto H, Hancock B, Cornax I, Pogliano J, Sakoulas G, Nizet V. PMID: 31353294.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    27. Inflammasome inhibition blocks cardiac glycoside cell toxicity. J Biol Chem. 2019 08 23; 294(34):12846-12854. LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. PMID: 31300552.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    28. Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance. J Infect Dis. 2019 07 02; 220(3):484-493. Ulloa ER, Dillon N, Tsunemoto H, Pogliano J, Sakoulas G, Nizet V. PMID: 30923801.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin. Antimicrob Agents Chemother. 2019 07; 63(7). Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL. PMID: 31235559.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli. J Innate Immun. 2019; 11(6):481-495. Patras KA, Ha AD, Rooholfada E, Olson J, Ramachandra Rao SP, Lin AE, Nizet V. PMID: 31055580.
      View in: PubMed   Mentions: 1     Fields:    
    31. An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model. mBio. 2019 04 30; 10(2). Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. PMID: 31040243.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    32. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media. Sci Data. 2019 04 26; 6(1):43. Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, Nizet V, Palsson BO, Feist AM. PMID: 31028276.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    33. Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2019 05; 63(5). Geriak M, Haddad F, Rizvi K, Rose W, Kullar R, LaPlante K, Yu M, Vasina L, Ouellette K, Zervos M, Nizet V, Sakoulas G. PMID: 30858203.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    34. Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion. Front Pharmacol. 2019; 10:323. Meier A, Chien J, Hobohm L, Patras KA, Nizet V, Corriden R. PMID: 31024300.
      View in: PubMed   Mentions:
    35. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019 04 15; 38(8). Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, Rana TM. PMID: 30918008.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    36. Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7465-7470. Uchiyama S, Sun J, Fukahori K, Ando N, Wu M, Schwarz F, Siddiqui SS, Varki A, Marth JD, Nizet V. PMID: 30910970.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. Proton-pump inhibitors do not influence clinical outcomes in patients with Staphylococcus aureus bacteremia. Therap Adv Gastroenterol. 2019; 12:1756284819834273. Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G. PMID: 30923573.
      View in: PubMed   Mentions:
    38. Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry. Cell Chem Biol. 2019 05 16; 26(5):724-736.e7. Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS. PMID: 30853419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    39. Impact of Anesthetics on Human Neutrophil Function. Anesth Analg. 2019 03; 128(3):569-574. Meier A, Nizet V. PMID: 30507837.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    40. Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria. Chem Biol Drug Des. 2019 04; 93(4):647-652. Huang YM, Munguia J, Miao Y, Nizet V, McCammon JA. PMID: 30570806.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    41. Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells. Sci Transl Med. 2019 02 06; 11(478). Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, Nizet V, Bothwell M, Brigger M, Crotty S. PMID: 30728285.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    42. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ. 2019 03; 26(3):395-408. Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M. PMID: 30622307.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    43. Is a Reported Penicillin Allergy Sufficient Grounds to Forgo the Multidimensional Antimicrobial Benefits of ß-Lactam Antibiotics? Clin Infect Dis. 2019 01 01; 68(1):157-164. Sakoulas G, Geriak M, Nizet V. PMID: 29986019.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection. Toxins (Basel). 2018 12 17; 10(12). Escajadillo T, Nizet V. PMID: 30562923.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    45. The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus. BMC Microbiol. 2018 11 26; 18(1):197. Vrbanac A, Riestra AM, Coady A, Knight R, Nizet V, Patras KA. PMID: 30477439.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    46. Erratum for Schooley et al., "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection". Antimicrob Agents Chemother. 2018 12; 62(12). Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. PMID: 30478181.
      View in: PubMed   Mentions: 3     Fields:    
    47. Tamm-Horsfall Protein Protects the Urinary Tract against Candida albicans. Infect Immun. 2018 12; 86(12). Coady A, Ramos AR, Olson J, Nizet V, Patras KA. PMID: 30297523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    48. Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages. J Innate Immun. 2019; 11(1):86-98. Riestra AM, Valderrama JA, Patras KA, Booth SD, Quek XY, Tsai CM, Nizet V. PMID: 30391945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    49. Enhanced topical delivery of non-complexed molecular iodine for Methicillin-resistant Staphylococcus aureus decolonization. Int J Pharm. 2019 Jan 10; 554:81-86. Uchiyama S, Dahesh S, Nizet V, Kessler J. PMID: 30395958.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    50. Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. Nat Commun. 2018 10 17; 9(1):4306. Kavvas ES, Catoiu E, Mih N, Yurkovich JT, Seif Y, Dillon N, Heckmann D, Anand A, Yang L, Nizet V, Monk JM, Palsson BO. PMID: 30333483.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
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    132. Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan. Cell Host Microbe. 2015 Dec 09; 18(6):694-704. Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. PMID: 26651945.
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    133. Streptococcal toxins: role in pathogenesis and disease. Cell Microbiol. 2015 Dec; 17(12):1721-41. Barnett TC, Cole JN, Rivera-Hernandez T, Henningham A, Paton JC, Nizet V, Walker MJ. PMID: 26433203.
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    137. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nat Commun. 2015 Oct 13; 6:8369. Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. PMID: 26458291.
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    145. Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infect Immun. 2015 Sep; 83(9):3648-56. Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC. PMID: 26150541.
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    148. Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase. Chembiochem. 2015 Jul 06; 16(10):1443-7. Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS. PMID: 25930739.
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    149. In vitro activity of daptomycin in combination with ß-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci. Antimicrob Agents Chemother. 2015 Jul; 59(7):4279-88. Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R. PMID: 25963982.
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    151. Role of Hypoxia Inducible Factor-1a (HIF-1a) in Innate Defense against Uropathogenic Escherichia coli Infection. PLoS Pathog. 2015 Apr; 11(4):e1004818. Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V. PMID: 25927232.
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    161. The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-?B signaling, and inflammatory gene expression in human aortic valve cells. FASEB J. 2015 May; 29(5):1859-68. Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. PMID: 25630970.
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    209. Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions. Cell Host Microbe. 2013 Sep 11; 14(3):294-305. Guichard A, Cruz-Moreno B, Cruz-Moreno BC, Aguilar B, van Sorge NM, Kuang J, Kurkciyan AA, Wang Z, Hang S, Pineton de Chambrun GP, McCole DF, Watnick P, Nizet V, Bier E. PMID: 24034615.
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    216. A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection. PLoS Pathog. 2013; 9(7):e1003469. Sanderson-Smith ML, Zhang Y, Ly D, Donahue D, Hollands A, Nizet V, Ranson M, Ploplis VA, Walker MJ, Castellino FJ. PMID: 23853591.
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    222. Succinate is an inflammatory signal that induces IL-1ß through HIF-1a. Nature. 2013 Apr 11; 496(7444):238-42. Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA. PMID: 23535595.
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    257. Novel bacterial metabolite merochlorin A demonstrates in vitro activity against multi-drug resistant methicillin-resistant Staphylococcus aureus. PLoS One. 2012; 7(1):e29439. Sakoulas G, Nam SJ, Loesgen S, Fenical W, Jensen PR, Nizet V, Hensler M. PMID: 22279537.
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    258. Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics. Antimicrob Agents Chemother. 2012 Apr; 56(4):1854-61. McGillivray SM, Tran DN, Ramadoss NS, Alumasa JN, Okumura CY, Sakoulas G, Vaughn MM, Zhang DX, Keiler KC, Nizet V. PMID: 22252821.
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    259. Leukocyte inflammatory responses provoked by pneumococcal sialidase. mBio. 2012; 3(1). Chang YC, Uchiyama S, Varki A, Nizet V. PMID: 22215570.
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    260. The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One. 2011; 6(12):e29122. Kho MF, Bellier A, Balasubramani V, Hu Y, Hsu W, Nielsen-LeRoux C, McGillivray SM, Nizet V, Aroian RV. PMID: 22216181.
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    261. Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012 Feb; 56(2):838-44. Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA. PMID: 22123698.
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    262. Improved diagnostic accuracy of group A streptococcal pharyngitis with use of real-time biosurveillance. Ann Intern Med. 2011 Sep 20; 155(6):345-52. Fine AM, Nizet V, Mandl KD. PMID: 21930851.
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    263. Molecular insight into invasive group A streptococcal disease. Nat Rev Microbiol. 2011 Sep 16; 9(10):724-36. Cole JN, Barnett TC, Nizet V, Walker MJ. PMID: 21921933.
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    264. New insights into the biological effects of anthrax toxins: linking cellular to organismal responses. Microbes Infect. 2012 Feb; 14(2):97-118. Guichard A, Nizet V, Bier E. PMID: 21930233.
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    265. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat Immunol. 2011 Sep 04; 12(10):966-74. Kinjo Y, Illarionov P, Vela JL, Pei B, Girardi E, Li X, Li Y, Imamura M, Kaneko Y, Okawara A, Miyazaki Y, Gómez-Velasco A, Rogers P, Dahesh S, Uchiyama S, Khurana A, Kawahara K, Yesilkaya H, Andrew PW, Wong CH, Kawakami K, Nizet V, Besra GS, Tsuji M, Zajonc DM, Kronenberg M. PMID: 21892173.
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    266. Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. J Innate Immun. 2012; 4(2):213-8. Zinkernagel AS, Hruz P, Uchiyama S, von Köckritz-Blickwede M, Schuepbach RA, Hayashi T, Carson DA, Nizet V. PMID: 21860217.
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    267. A randomized controlled trial of motavizumab versus palivizumab for the prophylaxis of serious respiratory syncytial virus disease in children with hemodynamically significant congenital heart disease. Pediatr Res. 2011 Aug; 70(2):186-91. Feltes TF, Sondheimer HM, Tulloh RM, Harris BS, Jensen KM, Losonsky GA, Griffin MP. PMID: 21522037.
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    268. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein. J Biol Chem. 2011 Sep 30; 286(39):33981-91. Nordström T, Movert E, Olin AI, Ali SR, Nizet V, Varki A, Areschoug T. PMID: 21795693.
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    269. Use of antistaphylococcal beta-lactams to increase daptomycin activity in eradicating persistent bacteremia due to methicillin-resistant Staphylococcus aureus: role of enhanced daptomycin binding. Clin Infect Dis. 2011 Jul 15; 53(2):158-63. Dhand A, Bayer AS, Pogliano J, Yang SJ, Bolaris M, Nizet V, Wang G, Sakoulas G. PMID: 21690622.
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    270. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology. 2011 Sep; 157(Pt 9):2485-2492. Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. PMID: 21719540.
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    271. Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp. Bioorg Med Chem. 2011 Nov 15; 19(22):6557-62. Sun P, Maloney KN, Nam SJ, Haste NM, Raju R, Aalbersberg W, Jensen PR, Nizet V, Hensler ME, Fenical W. PMID: 21745747.
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    272. Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems. PLoS Pathog. 2011 Jun; 7(6):e1002082. Chang YC, Wang Z, Flax LA, Xu D, Esko JD, Nizet V, Baron MJ. PMID: 21731486.
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    273. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 2011 Jul 22; 35(1):34-44. Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. PMID: 21683629.
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    274. Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Dev Comp Immunol. 2012 Jan; 36(1):31-8. Carland TM, Locke JB, Nizet V, Gerwick L. PMID: 21683091.
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    275. Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence. BMC Microbiol. 2011 May 27; 11:120. Sjögren J, Okumura CY, Collin M, Nizet V, Hollands A. PMID: 21619648.
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    276. The FbaB-type fibronectin-binding protein of Streptococcus pyogenes promotes specific invasion into endothelial cells. Cell Microbiol. 2011 Aug; 13(8):1200-11. Amelung S, Nerlich A, Rohde M, Spellerberg B, Cole JN, Nizet V, Chhatwal GS, Talay SR. PMID: 21615663.
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    277. Total synthesis and biological evaluation of marinopyrrole A and analogues. Tetrahedron Lett. 2011 Apr 27; 52(17):2041-2043. Nicolaou KC, Simmons NL, Chen JS, Haste NM, Nizet V. PMID: 21499535.
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    278. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus. Mar Drugs. 2011; 9(4):680-9. Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. PMID: 21731557.
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    279. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2011 Jul; 55(7):3305-12. Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. PMID: 21502631.
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    280. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl). 2011 Oct; 89(10):997-1013. Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. PMID: 21499735.
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    281. Streptococcal M1 protein constructs a pathological host fibrinogen network. Nature. 2011 Apr 07; 472(7341):64-8. Macheboeuf P, Buffalo C, Fu CY, Zinkernagel AS, Cole JN, Johnson JE, Nizet V, Ghosh P. PMID: 21475196.
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    282. Papillation in Bacillus anthracis colonies: a tool for finding new mutators. Mol Microbiol. 2011 Mar; 79(5):1276-93. Yang H, Sikavi C, Tran K, McGillivray SM, Nizet V, Yung M, Chang A, Miller JH. PMID: 21205011.
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    283. Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis. 2011 Feb 01; 203(3):393-400. Reiss A, Braun JS, Jäger K, Freyer D, Laube G, Bührer C, Felderhoff-Müser U, Stadelmann C, Nizet V, Weber JR. PMID: 21186256.
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    284. IL-1ß-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKß. Nat Immunol. 2011 Feb; 12(2):144-50. Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. PMID: 21170027.
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    285. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010 Nov 18; 8(5):445-54. Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. PMID: 21075355.
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    286. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. Nature. 2010 Oct 14; 467(7317):854-8. Guichard A, McGillivray SM, Cruz-Moreno B, van Sorge NM, Nizet V, Bier E. PMID: 20944747.
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    288. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J Innate Immun. 2010; 2(6):576-86. Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, von Köckritz-Blickwede M. PMID: 20829609.
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    289. Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. J Innate Immun. 2010; 2(6):596-606. Maamary PG, Sanderson-Smith ML, Aziz RK, Hollands A, Cole JN, McKay FC, McArthur JD, Kirk JK, Cork AJ, Keefe RJ, Kansal RG, Sun H, Taylor WL, Chhatwal GS, Ginsburg D, Nizet V, Kotb M, Walker MJ. PMID: 20814186.
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    292. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16286-90. Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. PMID: 20805502.
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    293. On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity. Bioorg Med Chem Lett. 2010 Oct 01; 20(19):5701-4. Derbal S, Hensler M, Fang W, Nizet V, Ghedira K, Nefzi A. PMID: 20800485.
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    294. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010 Jul 23; 5(7):e11701. Zhao HW, Zhou D, Nizet V, Haddad GG. PMID: 20668515.
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    295. Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid. J Exp Med. 2010 Aug 02; 207(8):1637-46. Taylor RE, Gregg CJ, Padler-Karavani V, Ghaderi D, Yu H, Huang S, Sorensen RU, Chen X, Inostroza J, Nizet V, Varki A. PMID: 20624889.
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    296. Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem. 2010 Sep 03; 285(36):27609-13. Rooijakkers SH, Rasmussen SL, McGillivray SM, Bartnikas TB, Mason AB, Friedlander AM, Nizet V. PMID: 20615872.
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    297. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. J Infect Dis. 2010 Jul 01; 202(1):11-9. Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, Walker MJ, Nizet V. PMID: 20507231.
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    298. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. PMID: 20581111.
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    299. The CXC chemokine-degrading protease SpyCep of Streptococcus pyogenes promotes its uptake into endothelial cells. J Biol Chem. 2010 Sep 03; 285(36):27798-805. Kaur SJ, Nerlich A, Bergmann S, Rohde M, Fulde M, Zähner D, Hanski E, Zinkernagel A, Nizet V, Chhatwal GS, Talay SR. PMID: 20562101.
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    300. O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. Biochem J. 2010 May 13; 428(2):163-8. Weiman S, Uchiyama S, Lin FY, Chaffin D, Varki A, Nizet V, Lewis AL. PMID: 20334627.
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    301. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2010 May; 63(5):219-24. Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. PMID: 20339399.
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    302. Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Dis Aquat Organ. 2010 Mar 09; 89(2):117-23. Locke JB, Vicknair MR, Ostland VE, Nizet V, Buchanan JT. PMID: 20402229.
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    304. Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract. Mol Microbiol. 2010 Jun; 76(6):1387-97. Kurupati P, Turner CE, Tziona I, Lawrenson RA, Alam FM, Nohadani M, Stamp GW, Zinkernagel AS, Nizet V, Edwards RJ, Sriskandan S. PMID: 20158613.
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    305. Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4329-34. Stockmann C, Kerdiles Y, Nomaksteinsky M, Weidemann A, Takeda N, Doedens A, Torres-Collado AX, Iruela-Arispe L, Nizet V, Johnson RS. PMID: 20142499.
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    306. Pathogen microevolution in high resolution. Sci Transl Med. 2010 Jan 27; 2(16):16ps4. Aziz RK, Nizet V. PMID: 20371473.
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    307. Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One. 2010 Jan 05; 5(1):e8557. Cogen AL, Yamasaki K, Muto J, Sanchez KM, Crotty Alexander L, Tanios J, Lai Y, Kim JE, Nizet V, Gallo RL. PMID: 20052280.
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    308. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol. 2010 Jan; 130(1):192-200. Cogen AL, Yamasaki K, Sanchez KM, Dorschner RA, Lai Y, MacLeod DT, Torpey JW, Otto M, Nizet V, Kim JE, Gallo RL. PMID: 19710683.
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    309. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 2009 Dec 10; 114(25):5245-6. von Köckritz-Blickwede M, Chow OA, Nizet V. PMID: 20007813.
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    310. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl). 2010 Apr; 88(4):371-81. Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. PMID: 19960175.
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    311. The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology. 2010 Feb; 156(Pt 2):543-54. Milani CJ, Aziz RK, Locke JB, Dahesh S, Nizet V, Buchanan JT. PMID: 19762441.
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    312. Interdependence of hypoxic and innate immune responses. Nat Rev Immunol. 2009 Sep; 9(9):609-17. Nizet V, Johnson RS. PMID: 19704417.
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    314. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med. 2009 Aug 31; 206(9):1845-52. Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. PMID: 19687228.
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    315. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 2009 Nov; 19(11):1204-13. Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. PMID: 19643844.
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    316. Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13552-7. Lewis AL, Desa N, Hansen EE, Knirel YA, Gordon JI, Gagneux P, Nizet V, Varki A. PMID: 19666579.
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    317. Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin. J Leukoc Biol. 2009 Nov; 86(5):1159-69. Jann NJ, Schmaler M, Kristian SA, Radek KA, Gallo RL, Nizet V, Peschel A, Landmann R. PMID: 19638500.
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    318. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387. Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. PMID: 19633710.
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    322. NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12873-8. Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, Eckmann L. PMID: 19541630.
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    324. The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier. J Infect Dis. 2009 May 15; 199(10):1479-87. van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. PMID: 19392623.
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    325. Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes. PLoS One. 2009; 4(4):e5366. Cox KH, Ruiz-Bustos E, Courtney HS, Dale JB, Pence MA, Nizet V, Aziz RK, Gerling I, Price SM, Hasty DL. PMID: 19401780.
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    326. Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling. Immunol Cell Biol. 2009 Aug-Sep; 87(6):496-500. Pinheiro da Silva F, Gallo RL, Nizet V. PMID: 19350049.
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    327. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7107-12. Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. PMID: 19351895.
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    329. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem. 2009 May 08; 284(19):13004-12. Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. PMID: 19286651.
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    330. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. J Med Chem. 2009 Feb 26; 52(4):976-88. Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. PMID: 19191557.
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    331. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun. 2009; 1(3):202-14. Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. PMID: 20375578.
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    332. Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response. Blood. 2009 Apr 02; 113(14):3333-6. Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A. PMID: 19196661.
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    333. Bacterial phenotype variants in group B streptococcal toxic shock syndrome. Emerg Infect Dis. 2009 Feb; 15(2):223-32. Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, Norrby-Teglund A. PMID: 19193266.
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    334. Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes. PLoS One. 2009; 4(1):e4166. Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Podbielbski A, Hasty DL, Dale JB. PMID: 19132104.
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    335. A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence. PLoS One. 2008; 3(12):e4102. Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, Walker MJ. PMID: 19116661.
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    336. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. J Biol Chem. 2009 Jan 09; 284(2):862-71. Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. PMID: 19001420.
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    338. Mitochondrial missile defense. Nat Med. 2008 Sep; 14(9):910-2. Nizet V, Rothenberg ME. PMID: 18776879.
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    339. The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host Microbe. 2008 Aug 14; 4(2):170-8. Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, Nizet V. PMID: 18692776.
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    340. Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. PLoS One. 2008 Jul 30; 3(7):e2824. Locke JB, Aziz RK, Vicknair MR, Nizet V, Buchanan JT. PMID: 18665241.
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    341. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. PLoS One. 2008 Jun 18; 3(6):e2446. Hensler ME, Miyamoto S, Nizet V. PMID: 18560574.
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    342. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrob Agents Chemother. 2008 Aug; 52(8):2915-8. Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. PMID: 18541727.
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    343. The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses. BMC Microbiol. 2008 Jun 02; 8:85. Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, Peschel A. PMID: 18518949.
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    344. IKKbeta/NF-kappaB and the miscreant macrophage. J Exp Med. 2008 Jun 09; 205(6):1255-9. Timmer AM, Nizet V. PMID: 18519650.
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    345. Innate barriers against infection and associated disorders. Drug Discov Today Dis Mech. 2008 Jun 01; 5(2):145-152. Gallo RL, Nizet V. PMID: 19492071.
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    347. The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nat Med. 2008 Jun; 14(6):648-55. Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD. PMID: 18488037.
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    348. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 2008 Jun 05; 453(7196):807-11. Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. PMID: 18432192.
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    349. Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84. Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. PMID: 18375757.
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    350. Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass. Vet Microbiol. 2008 Sep 18; 131(1-2):145-53. Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, Nizet V. PMID: 18406547.
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    351. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science. 2008 Mar 07; 319(5868):1405-8. McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. PMID: 18323455.
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    352. Critical role of HIF-1alpha in keratinocyte defense against bacterial infection. J Invest Dermatol. 2008 Aug; 128(8):1964-8. Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, Johnson RS. PMID: 18323789.
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    353. Skin microbiota: a source of disease or defence? Br J Dermatol. 2008 Mar; 158(3):442-55. Cogen AL, Nizet V, Gallo RL. PMID: 18275522.
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    354. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 07; 319(5868):1391-4. Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. PMID: 18276850.
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    355. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. J Bacteriol. 2008 Apr; 190(7):2275-8. Park B, Nizet V, Liu GY. PMID: 18223076.
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    356. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J. 2008 Jun; 22(6):1715-24. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. PMID: 18198218.
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    357. Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes. J Infect Dis. 2008 Jan 15; 197(2):214-7. Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. PMID: 18173364.
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    358. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. J Biol Chem. 2008 Mar 07; 283(10):6359-66. Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, Walker MJ. PMID: 18180300.
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    359. Role of the hypoxia inducible factors HIF in iron metabolism. Cell Cycle. 2008 Jan 01; 7(1):28-32. Peyssonnaux C, Nizet V, Johnson RS. PMID: 18212530.
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    360. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 2007 Dec; 7(24):4488-98. Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, Walker MJ. PMID: 18072207.
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    361. Hypoxia inducible factor (HIF) function in innate immunity and infection. J Mol Med (Berl). 2007 Dec; 85(12):1339-46. Zinkernagel AS, Johnson RS, Nizet V. PMID: 18030436.
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    362. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorg Med Chem Lett. 2008 May 15; 18(10):3107-11. Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. PMID: 18006314.
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    363. CAMP factor is not essential for systemic virulence of Group B Streptococcus. Microb Pathog. 2008 Jan; 44(1):84-8. Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. PMID: 17870297.
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    364. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. J Biol Chem. 2007 Sep 21; 282(38):27562-71. Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. PMID: 17646166.
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    365. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med. 2007 Aug; 13(8):981-5. Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, Henningham A, McArthur JD, Dinkla K, Aziz RK, Kansal RG, Simpson AJ, Buchanan JT, Chhatwal GS, Kotb M, Nizet V. PMID: 17632528.
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    366. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood. 2007 Oct 15; 110(8):3039-48. Bayele HK, Peyssonnaux C, Giatromanolaki A, Arrais-Silva WW, Mohamed HS, Collins H, Giorgio S, Koukourakis M, Johnson RS, Blackwell JM, Nizet V, Srai SK. PMID: 17606764.
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    367. Understanding how leading bacterial pathogens subvert innate immunity to reveal novel therapeutic targets. J Allergy Clin Immunol. 2007 Jul; 120(1):13-22. Nizet V. PMID: 17606031.
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    368. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest. 2007 Jul; 117(7):1926-32. Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. PMID: 17557118.
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    369. Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis. J Immunol. 2007 Jun 15; 178(12):7516-9. Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V. PMID: 17548584.
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    370. Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection. Dis Aquat Organ. 2007 Jun 07; 76(1):17-26. Locke JB, Colvin KM, Varki N, Vicknair MR, Nizet V, Buchanan JT. PMID: 17718161.
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    371. Staphylococcus aureus: a blemish on skin immunity. Cell Host Microbe. 2007 May 17; 1(3):161-2. Zinkernagel AS, Nizet V. PMID: 18005694.
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    372. How group A Streptococcus circumvents host phagocyte defenses. Future Microbiol. 2007 Feb; 2(1):75-84. Kwinn LA, Nizet V. PMID: 17661677.
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    373. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. FASEB J. 2007 Apr; 21(4):1107-16. Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. PMID: 17215486.
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    374. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science. 2006 Dec 15; 314(5806):1792-5. Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. PMID: 17170310.
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    375. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. J Bacteriol. 2007 Feb; 189(4):1322-9. Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. PMID: 17114267.
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    376. Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. J Bacteriol. 2007 Feb; 189(4):1279-87. Locke JB, Colvin KM, Datta AK, Patel SK, Naidu NN, Neely MN, Nizet V, Buchanan JT. PMID: 17098893.
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    377. Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides. Infect Immun. 2006 Nov; 74(11):6179-87. Hamilton A, Popham DL, Carl DJ, Lauth X, Nizet V, Jones AL. PMID: 17057092.
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    378. Brain abscess caused by Streptococcus pyogenes in a previously healthy child. J Clin Microbiol. 2006 Dec; 44(12):4613-5. Dehority W, Uchiyama S, Khosravi A, Nizet V. PMID: 17065264.
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    379. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. J Bacteriol. 2007 Feb; 189(4):1464-7. Maisey HC, Hensler M, Nizet V, Doran KS. PMID: 17041051.
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    380. Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. J Bacteriol. 2007 Feb; 189(4):1231-7. Carlin AF, Lewis AL, Varki A, Nizet V. PMID: 16997964.
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    381. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. EMBO J. 2006 Oct 04; 25(19):4628-37. Hidalgo-Grass C, Mishalian I, Dan-Goor M, Belotserkovsky I, Eran Y, Nizet V, Peled A, Hanski E. PMID: 16977314.
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    382. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Mol Microbiol. 2006 Oct; 62(1):15-25. Timmer AM, Kristian SA, Datta V, Jeng A, Gillen CM, Walker MJ, Beall B, Nizet V. PMID: 16942605.
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    383. Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorg Med Chem Lett. 2006 Oct 01; 16(19):5073-9. Hensler ME, Bernstein G, Nizet V, Nefzi A. PMID: 16890437.
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    384. Trigger for group A streptococcal M1T1 invasive disease. FASEB J. 2006 Aug; 20(10):1745-7. Cole JN, McArthur JD, McKay FC, Sanderson-Smith ML, Cork AJ, Ranson M, Rohde M, Itzek A, Sun H, Ginsburg D, Kotb M, Nizet V, Chhatwal GS, Walker MJ. PMID: 16790522.
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    385. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006 Feb 24; 124(4):823-35. Karin M, Lawrence T, Nizet V. PMID: 16497591.
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    386. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr Biol. 2006 Feb 21; 16(4):396-400. Buchanan JT, Simpson AJ, Aziz RK, Liu GY, Kristian SA, Kotb M, Feramisco J, Nizet V. PMID: 16488874.
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    387. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. J Biol Chem. 2006 Apr 21; 281(16):11186-92. Lewis AL, Hensler ME, Varki A, Nizet V. PMID: 16490781.
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    388. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood. 2006 May 01; 107(9):3727-32. Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. PMID: 16391018.
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    389. Antimicrobial peptide resistance mechanisms of human bacterial pathogens. Curr Issues Mol Biol. 2006 Jan; 8(1):11-26. Nizet V. PMID: 16450883.
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    390. The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. FASEB J. 2006 Jan; 20(1):35-42. Dorschner RA, Lopez-Garcia B, Peschel A, Kraus D, Morikawa K, Nizet V, Gallo RL. PMID: 16394265.
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    391. D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol. 2005 Oct; 187(19):6719-25. Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V. PMID: 16166534.
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    392. Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. Infect Immun. 2005 Oct; 73(10):6935-44. Buchanan JT, Stannard JA, Lauth X, Ostland VE, Powell HC, Westerman ME, Nizet V. PMID: 16177373.
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    393. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun. 2005 Oct; 73(10):6771-81. Braff MH, Zaiou M, Fierer J, Nizet V, Gallo RL. PMID: 16177355.
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    394. Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest. 2005 Sep; 115(9):2499-507. Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. PMID: 16138192.
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    395. A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infect Immun. 2005 Aug; 73(8):4512-21. Georgel P, Crozat K, Lauth X, Makrantonaki E, Seltmann H, Sovath S, Hoebe K, Du X, Rutschmann S, Jiang Z, Bigby T, Nizet V, Zouboulis CC, Beutler B. PMID: 16040962.
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    396. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005 Jul 18; 202(2):209-15. Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. PMID: 16009720.
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    397. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest. 2005 Jul; 115(7):1806-15. Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS. PMID: 16007254.
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    398. Cutaneous defense mechanisms by antimicrobial peptides. J Invest Dermatol. 2005 Jul; 125(1):9-13. Braff MH, Bardan A, Nizet V, Gallo RL. PMID: 15982297.
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    400. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 2005 Apr 28; 434(7037):1138-43. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. PMID: 15858576.
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    401. Virulence role of group B Streptococcus beta-hemolysin/cytolysin in a neonatal rabbit model of early-onset pulmonary infection. J Infect Dis. 2005 Apr 15; 191(8):1287-91. Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP. PMID: 15776375.
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    402. Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections. J Biol Chem. 2005 Mar 11; 280(10):9272-82. Lauth X, Babon JJ, Stannard JA, Singh S, Nizet V, Carlberg JM, Ostland VE, Pennington MW, Norton RS, Westerman ME. PMID: 15546886.
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    404. Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14491-6. Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. PMID: 15381763.
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    405. Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):11123-8. Lewis AL, Nizet V, Varki A. PMID: 15263085.
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    406. Extracellular virulence factors of group B Streptococci. Front Biosci. 2004 May 01; 9:1794-802. Liu GY, Nizet V. PMID: 14977587.
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    407. Antimicrobial peptides and the skin. Expert Opin Biol Ther. 2004 Apr; 4(4):543-9. Bardan A, Nizet V, Gallo RL. PMID: 15102603.
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    408. Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections. Lancet. 2004 Feb 28; 363(9410):696-703. Hidalgo-Grass C, Dan-Goor M, Maly A, Eran Y, Kwinn LA, Nizet V, Ravins M, Jaffe J, Peyser A, Moses AE, Hanski E. PMID: 15001327.
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    409. Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol. 2004 Jan; 51(1):123-34. Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. PMID: 14651616.
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    410. Fulminant bacterial meningitis complicating sphenoid sinusitis. Pediatr Emerg Care. 2003 Dec; 19(6):415-7. Saitoh A, Beall B, Nizet V. PMID: 14676492.
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    411. Endogenous production of antimicrobial peptides in innate immunity and human disease. Curr Allergy Asthma Rep. 2003 Sep; 3(5):402-9. Gallo RL, Nizet V. PMID: 12906776.
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    412. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest. 2003 Sep; 112(5):736-44. Doran KS, Liu GY, Nizet V. PMID: 12952922.
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    413. Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. J Infect Dis. 2003 Aug 01; 188(3):414-23. Kristian SA, Lauth X, Nizet V, Goetz F, Neumeister B, Peschel A, Landmann R. PMID: 12870123.
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    414. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol. 2003 May; 120(5):810-6. Zaiou M, Nizet V, Gallo RL. PMID: 12713586.
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    415. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 2003 Mar 07; 112(5):645-57. Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. PMID: 12628185.
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    416. Molecular genetic analysis of a group A Streptococcus operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX. J Bacteriol. 2003 Feb; 185(4):1208-17. Jeng A, Sakota V, Li Z, Datta V, Beall B, Nizet V. PMID: 12562790.
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    417. Selective modulation of superantigen-induced responses by streptococcal cysteine protease. J Infect Dis. 2003 Feb 01; 187(3):398-407. Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. PMID: 12552423.
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    418. Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis. 2003; 35(9):670-6. Nizet V, Gallo RL. PMID: 14620153.
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    419. Streptococcal beta-hemolysins: genetics and role in disease pathogenesis. Trends Microbiol. 2002 Dec; 10(12):575-80. Nizet V. PMID: 12564994.
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    420. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and beta-hemolysin/cytolysin. J Infect Dis. 2002 Nov 15; 186(10):1518-21. Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. PMID: 12404173.
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    421. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. J Immunol. 2002 Oct 01; 169(7):3970-7. Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. PMID: 12244198.
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    422. Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun. 2002 Oct; 70(10):5730-9. Fuller JD, Camus AC, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JC. PMID: 12228303.
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    423. Surviving innate immunity. Trends Microbiol. 2002 Aug; 10(8):358-9. Nizet V, Gallo RL. PMID: 12160630.
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    424. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol. 2002 Jun; 22(4):326-30. Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. PMID: 12032798.
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    425. Group B streptococcal beta-hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis. 2002 Jun 15; 185(12):1745-53. Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. PMID: 12085320.
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    426. Streptolysin S and necrotising infections produced by group G streptococcus. Lancet. 2002 Jan 12; 359(9301):124-9. Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. PMID: 11809255.
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    427. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis. 2002 Jan 15; 185(2):196-203. Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. PMID: 11807693.
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    428. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol. 2001 Dec 15; 167(12):7069-76. Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. PMID: 11739528.
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    429. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15; 277(7):5030-9. Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. PMID: 11739390.
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    430. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 2001 Nov 22; 414(6862):454-7. Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. PMID: 11719807.
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    431. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol. 2001 Jul; 117(1):91-7. Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. PMID: 11442754.
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    432. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature. J Infect. 2001 May; 42(4):272-7. Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. PMID: 11545571.
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    433. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun. 2001 Apr; 69(4):1994-2000. Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC. PMID: 11254550.
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    434. Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus. Mol Microbiol. 2001 Jan; 39(2):236-47. Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V. PMID: 11136446.
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    435. Severity of group B streptococcal arthritis is correlated with beta-hemolysin expression. J Infect Dis. 2000 Sep; 182(3):824-32. Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. PMID: 10950777.
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    436. Genetic locus for streptolysin S production by group A streptococcus. Infect Immun. 2000 Jul; 68(7):4245-54. Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. PMID: 10858242.
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    437. Group B streptococcal beta-hemolysin induces nitric oxide production in murine macrophages. J Infect Dis. 2000 Jul; 182(1):150-7. Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. PMID: 10882592.
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    438. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun. 2000 Feb; 68(2):637-43. Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. PMID: 10639427.
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    439. Group B streptococcal beta-hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res. 1999 May; 45(5 Pt 1):626-34. Gibson RL, Nizet V, Rubens CE. PMID: 10231855.
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    440. Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun. 1997 Dec; 65(12):5074-81. Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. PMID: 9393798.
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    441. The role of group B streptococci beta-hemolysin expression in newborn lung injury. Adv Exp Med Biol. 1997; 418:627-30. Nizet V, Gibson RL, Rubens CE. PMID: 9331730.
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    442. Epithelial cell invasion by group B streptococci is important to virulence. Adv Exp Med Biol. 1997; 418:631-4. La Penta D, Framson P, Nizet V, Rubens C. PMID: 9331731.
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    443. Group B streptococcal beta-hemolysin expression is associated with injury of lung epithelial cells. Infect Immun. 1996 Sep; 64(9):3818-26. Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. PMID: 8751934.
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    444. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella. J Pediatr Orthop. 1996 Jul-Aug; 16(4):522-8. Mills WJ, Mosca VS, Nizet V. PMID: 8784712.
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    445. Streptococcal skin infections. N Engl J Med. 1996 May 30; 334(22):1478. Brogan TV, Nizet V, Waldhausen JH. PMID: 8618597.
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    446. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis. 1996 Jan; 173(1):180-6. Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. PMID: 8537657.
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    447. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. Pediatr Infect Dis J. 1995 Jul; 14(7):588-94. Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. PMID: 7567287.
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    448. A newborn girl with watery diarrhea, weight loss, and severe metabolic acidosis. Curr Opin Pediatr. 1994 Apr; 6(2):163-7. Nizet V, Priebe CJ. PMID: 8032396.
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    449. Fever in children. Pediatr Rev. 1994 Apr; 15(4):127-35. Nizet V, Vinci RJ, Lovejoy FH. PMID: 8015996.
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    450. A 5-year-old girl with varicella and acute onset of fever, stridor, and respiratory distress. Curr Opin Pediatr. 1994 Feb; 6(1):36-41. Priebe CJ, Nizet V. PMID: 8205172.
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    451. A 7-month-old boy with poor growth, hypercalcemia, and unusual facies. Curr Opin Pediatr. 1993 Dec; 5(6):728-32. Priebe CJ, Nizet V. PMID: 8124427.
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    452. Common etiologies and new approaches to management of poisoning in pediatric practice. Curr Opin Pediatr. 1993 Oct; 5(5):524-30. Lovejoy FH, Nizet V, Priebe CJ. PMID: 8287075.
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    453. A 2-year-old girl with hematemesis, melena, and splenomegaly. Curr Opin Pediatr. 1993 Oct; 5(5):590-4. Priebe CJ, Nizet V. PMID: 8287083.
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    454. An 8-day-old male infant with poor feeding, lethargy, and an elevated anion gap metabolic acidosis. Curr Opin Pediatr. 1993 Aug; 5(4):499-502. Nizet V, Priebe CJ. PMID: 8374680.
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    455. Characterization of in vivo expression of the human papillomavirus type 16 E4 protein in cervical biopsy tissues. J Clin Invest. 1991 Jun; 87(6):2132-41. Palefsky JM, Winkler B, Rabanus JP, Clark C, Chan S, Nizet V, Schoolnik GK. PMID: 1645754.
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