Loading...

Victor Nizet

Title(s)Distinguished Professor, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0760
La Jolla CA 92093
Phone858-534-7408
vCardDownload vCard
    Other Positions
    Title(s)Distinguished Professor, School of Pharmacy and Pharmaceutical Science


    Collapse Biography 
    Collapse Education and Training
    Reed College, Portland, ORBA05/1984Biology
    Stanford University, Stanford, CAMD05/1989Medicine
    Collapse Awards and Honors
    2019NIH/NIAID Merit Award (R37)
    2019ISI Highly Cited Researcher (Cross-Field)
    2018Inaugural UCSD Health Sciences Award for Excellence in Junior Faculty Mentoring
    2017UCSD Chancellor's Associates Award for Excellence in Research in Science & Engineering
    2013UCSD Chancellor's Award for Excellence in Postdoctoral Scholar Mentoring
    2013Rady Children’s Hospital Award for Excellence in Research
    2012Elected to Fellowship in the American Academy of Microbiology
    2010Elected to Membership in the Association of American Physicians
    2008E. Mead Johnson Award for Research in Pediatrics, Society for Pediatric Research
    2008Stephen Silberstein Senior Fellow of the American Asthma Foundation
    2006Elected to Membership in the American Society for Clinical Investigation
    2006Elected to the American Pediatric Society
    2004Career Investigator Award, American Lung Association
    2004Established Investigator Award, American Heart Association
    2002Named the 39th Mallinckrodt Scholar by the Edward Mallinckrodt, Jr. Foundation
    2002Pediatric Infectious Diseases Society Young Investigator Award
    2002Elected to the Society for Pediatric Research
    2001UCSD Department of Pediatrics Commitment to Resident Education Award
    2000UCSD Department of Pediatrics Outstanding Faculty Teacher of the Year
    1993Sidney Farber Outstanding Houseofficer Award, Children’s Hospital, Boston
    1984Class of 1922 Award, Reed College, “Most Outstanding Senior Thesis”
    1984Phi Beta Kappa, Reed College

    Collapse Overview 
    Collapse Overview
    Victor Nizet is a Distinguished Professor and Vice Chair for Basic Research and Chief of the Division of Host-Microbe Systems & Therapeutics at the University of California, San Diego (UCSD), School of Medicine and Distinguished Professor at UCSD Skaggs School of Pharmacy & Pharmaceutical Sciences. Dr. Nizet is a graduate of Reed College, received his medical training at Stanford University School of Medicine, completed a Residency and Chief Residency in Pediatrics at Harvard University's Children's Hospital in Boston, Massachusetts, and a then a Fellowship in Pediatric Infectious Diseases at the University of Washington’s Children's Hospital in Seattle. Dr. Nizet is Faculty Lead for the UCSD Collaborative to Halt Antibiotic-Resistant Microbes (CHARM), a multidisciplinary research and educational program that debuted in Fall 2019. Dr. Nizet has authored over 440 peer-reviewed publications and has collaborated with several biotechnology interests in developing new antibiotic and immune-based therapies against drug-resistant pathogens. Details of his research program can be found on the laboratory website: http://nizetlab.ucsd.edu
    Collapse Interests

    Collapse Research 
    Collapse Research Activities and Funding
    Surprising Efficacy of Discounted Antibiotics vs. MDR Gram-Negative Pathogens Occurring Through Innate Immune Sensitization
    NIH/NIAID R01AI145310Aug 1, 2020 - Jul 31, 2024
    Role: Principal Investigator
    Glycan-Lectin Receptor Regulation of Macrophage Maturation and Lung Innate Defenses in the Fetus and Newborn Infant
    NIH/NIAID R01AI142864Jul 17, 2019 - Jun 30, 2022
    Role: Co-Principal Investigator
    C3-Dependent Intracellular Killing in Innate Immunity and Bacterial Pathogenesis
    NIH/NIAID R01AI145325Mar 5, 2019 - Feb 29, 2024
    Role: Co-Principal Investigator
    2018 Streptococcal Biology Gordon Research Conference
    NIH/NIAID R13AI140636Jul 1, 2018 - Jun 30, 2019
    Role: Principal Investigator
    Broad recognition of group A Streptococcus M proteins
    NIH/NIAID R21AI140436May 18, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH/NICHD P50HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Co-Principal Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH/NICHD U54HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Glycoprotein Remodeling in the Vasculopathy and Coagulopathy of Sepsis
    NIH/NHLBI R01HL125352Sep 15, 2014 - May 31, 2019
    Role: Principal Investigator
    Analyzing a novel mechanism of action of bacterial cAMP producing toxins
    NIH/NIAID R01AI110713Feb 1, 2014 - Jan 31, 2019
    Role: Principal Investigator
    Mechanisms of the M protein in group A Streptococcus virulence
    NIH/NIAID R56AI096837Jul 1, 2011 - Jul 31, 2019
    Role: Co-Principal Investigator
    Glycan Modulation of Inflammatory Responses
    NIH P01HL107150Jul 1, 2011 - May 31, 2018
    Role: Co-Investigator
    Mechanisms of the M protein in group A Streptococcus virulence
    NIH/NIAID R01AI096837Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections
    NIH/NIAID R01AI093451Apr 5, 2011 - Mar 31, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Drug-Resistant Bacterial Infections
    NIH/NIAID R56AI090863Aug 2, 2010 - Jul 31, 2011
    Role: Principal Investigator
    GAS Switch from Colonizing Bacterium to Invasive Pathogen
    NIH/NIAID R01AI077780Sep 1, 2008 - Jan 31, 2020
    Role: Principal Investigator
    Sialic Acid O-Acetylation in GBS Pathogenesis &Immunity
    NIH/NICHD R01HD051796Apr 7, 2006 - Feb 28, 2012
    Role: Principal Investigator
    Molecular Analyses and Interventions for Biodefense and Emerging Pathogens
    NIH U54AI057153Sep 4, 2003 - Feb 28, 2014
    Role: Co-Investigator
    Cathelicidin in Skin Immunity
    NIH/NIAID R37AI052453Sep 15, 2002 - Feb 29, 2024
    Role: Co-Principal Investigator
    Cathelicidin in Skin Immunity
    NIH/NIAID R01AI052453Sep 15, 2002 - Nov 30, 2017
    Role: Principal Investigator
    SLS: Molecular Basis and Role in Invasive GAS Disease
    NIH/NIAID R01AI048694Apr 1, 2002 - Mar 31, 2007
    Role: Principal Investigator
    PENETRATION OF THE BLOOD BRAIN BARRIER IN GBS MENINGITIS
    NIH/NICHD R03HD037224Feb 1, 1999 - Jan 31, 2001
    Role: Principal Investigator
    MOLECULAR BASIS OF LUNG INJURY IN GBS PNEUMONIA
    NIH/NIAID K08AI001451Apr 1, 1997 - Mar 31, 2001
    Role: Principal Investigator
    Research in Infectious Disease
    NIH/NIAID T32AI007036Jul 1, 1976 - May 31, 2004
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 2020 Sep 03; 182(5):1311-1327.e14. Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. PMID: 32888495.
      View in: PubMed   Mentions:    Fields:    
    2. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B Streptococcus. mSystems. 2020 Aug 25; 5(4). Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. PMID: 32843537.
      View in: PubMed   Mentions:
    3. Opportunistic Invasive Infection by Group A Streptococcus During Anti-Interleukin-6 Immunotherapy. J Infect Dis. 2020 Aug 18. Wilde S, Olivares KL, Nizet V, Hoffman HM, Radhakrishna S, LaRock CN. PMID: 32808035.
      View in: PubMed   Mentions:    Fields:    
    4. T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 Streptococcus pyogenes. mBio. 2020 Jul 21; 11(4). Chen YH, Li SH, Yang YC, Hsu SH, Nizet V, Chang YC. PMID: 32694142.
      View in: PubMed   Mentions:    Fields:    
    5. Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections. Open Forum Infect Dis. 2020 Aug; 7(8):ofaa302. Berti A, Rose W, Nizet V, Sakoulas G. PMID: 32818143.
      View in: PubMed   Mentions:
    6. An irreversible inhibitor to probe the role of Streptococcus pyogenes cysteine protease SpeB in evasion of host complement defenses. ACS Chem Biol. 2020 Jul 14. Woehl JL, Kitamura S, Dillon N, Han Z, Edgar LJ, Nizet V, Wolan DW. PMID: 32662975.
      View in: PubMed   Mentions:    Fields:    
    7. Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators, and role in key physiological response. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):17228-17239. Poudel S, Tsunemoto H, Seif Y, Sastry AV, Szubin R, Xu S, Machado H, Olson CA, Anand A, Pogliano J, Nizet V, Palsson BO. PMID: 32616573.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    8. Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. J Am Chem Soc. 2020 Jun 24; 142(25):10899-10904. Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. PMID: 32479075.
      View in: PubMed   Mentions:    Fields:    
    9. Interleukin (IL)-1ß and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy. Clin Infect Dis. 2020 Jun 10; 70(12):2634-2640. Volk CF, Burgdorf S, Edwardson G, Nizet V, Sakoulas G, Rose WE. PMID: 31365924.
      View in: PubMed   Mentions: 4     Fields:    
    10. Developmental Immaturity of Siglec Receptor Expression on Neonatal Alveolar Macrophages Predisposes to Severe Group B Streptococcal Infection. iScience. 2020 Jun 26; 23(6):101207. Lund SJ, Patras KA, Kimmey JM, Yamamura A, Butcher LD, Del Rosario PGB, Hernandez GE, McCoy AM, Lakhdari O, Nizet V, Prince LS. PMID: 32535023.
      View in: PubMed   Mentions:
    11. All major cholesterol-dependent cytolysins use glycans as cellular receptors. Sci Adv. 2020 May; 6(21):eaaz4926. Shewell LK, Day CJ, Jen FE, Haselhorst T, Atack JM, Reijneveld JF, Everest-Dass A, James DBA, Boguslawski KM, Brouwer S, Gillen CM, Luo Z, Kobe B, Nizet V, von Itzstein M, Walker MJ, Paton AW, Paton JC, Torres VJ, Jennings MP. PMID: 32494740.
      View in: PubMed   Mentions:    Fields:    
    12. Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection. PLoS Genet. 2020 05; 16(5):e1008795. Kuang E, Okumura CYM, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. PMID: 32392217.
      View in: PubMed   Mentions:    Fields:    
    13. Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis. Chembiochem. 2020 Apr 28. Li Y, Fin A, Rovira AR, Su Y, Dippel AB, Valderrama JA, Riestra AM, Nizet V, Hammond MC, Tor Y. PMID: 32346955.
      View in: PubMed   Mentions:    Fields:    
    14. Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection. mSphere. 2020 04 22; 5(2). Patras KA, Coady A, Babu P, Shing SR, Ha AD, Rooholfada E, Brandt SL, Geriak M, Gallo RL, Nizet V. PMID: 32321824.
      View in: PubMed   Mentions:    Fields:    
    15. How Neutrophils Meet Their End. Trends Immunol. 2020 Jun; 41(6):531-544. Lawrence SM, Corriden R, Nizet V. PMID: 32303452.
      View in: PubMed   Mentions: 1     Fields:    
    16. Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. mSystems. 2020 Mar 31; 5(2). Salazar MJ, Machado H, Dillon NA, Tsunemoto H, Szubin R, Dahesh S, Pogliano J, Sakoulas G, Palsson BO, Nizet V, Feist AM. PMID: 32234776.
      View in: PubMed   Mentions:
    17. Role of peribrachial fat as a key determinant of brachial artery dilatation for successful arteriovenous fistula maturation in hemodialysis patients. Sci Rep. 2020 03 02; 10(1):3841. Lee HS, Park MJ, Yoon SY, Joo N, Song YR, Kim HJ, Kim SG, Nizet V, Kim JK. PMID: 32123226.
      View in: PubMed   Mentions:    Fields:    
    18. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. 2020 03; 579(7797):123-129. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. PMID: 32103176.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    19. The Fungal Pathogen Candida albicans Promotes Bladder Colonization of Group B Streptococcus. Front Cell Infect Microbiol. 2019; 9:437. Shing SR, Ramos AR, Patras KA, Riestra AM, McCabe S, Nizet V, Coady A. PMID: 31998657.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    20. Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program. Genes Dev. 2020 02 01; 34(3-4):149-165. Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C. PMID: 31919189.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Siglecs at the Host-Pathogen Interface. Adv Exp Med Biol. 2020; 1204:197-214. Chang YC, Nizet V. PMID: 32152948.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media. Sci Data. 2019 12 17; 6(1):322. Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, Nizet V, Palsson BO, Feist AM, Pogliano J. PMID: 31848353.
      View in: PubMed   Mentions:    Fields:    
    23. A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus. Nat Commun. 2019 12 16; 10(1):5726. Valderrama JA, Kulkarni SS, Nizet V, Bier E. PMID: 31844051.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    24. Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages. J Innate Immun. 2020; 12(4):333-343. Tsai CM, Riestra AM, Ali SR, Fong JJ, Liu JZ, Hughes G, Varki A, Nizet V. PMID: 31805552.
      View in: PubMed   Mentions: 3     Fields:    
    25. Homophilic protein interactions facilitate bacterial aggregation and IgG-dependent complex formation by the Streptococcus canis M protein SCM. Virulence. 2019 12; 10(1):194-206. Nerlich A, Lapschies AM, Kohler TP, Cornax I, Eichhorn I, Goldmann O, Krienke P, Bergmann S, Nizet V, Hammerschmidt S, Rohde M, Fulde M. PMID: 30829556.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia. Clin Infect Dis. 2019 Nov 27. Ulloa ER, Singh KV, Geriak M, Haddad F, Murray BE, Nizet V, Sakoulas G. PMID: 31773134.
      View in: PubMed   Mentions:    Fields:    
    27. Erythrocyte-Coated Nanoparticles Block Cytotoxic Effects of Group B Streptococcus ß-Hemolysin/Cytolysin. Front Pediatr. 2019; 7:410. Koo J, Escajadillo T, Zhang L, Nizet V, Lawrence SM. PMID: 31737584.
      View in: PubMed   Mentions:
    28. Reply to Kalil et al., "Is Daptomycin plus Ceftaroline Associated with Better Clinical Outcomes than Standard of Care Monotherapy for Staphylococcus aureus Bacteremia?" Antimicrob Agents Chemother. 2019 11; 63(11). Sakoulas G, Geriak M, Haddad F, Rose W, LaPlante K, Zervos M, Kullar R, Nizet V. PMID: 31640978.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Strain-Specific Metabolic Requirements Revealed by a Defined Minimal Medium for Systems Analyses of Staphylococcus aureus. Appl Environ Microbiol. 2019 11 01; 85(21). Machado H, Weng LL, Dillon N, Seif Y, Holland M, Pekar JE, Monk JM, Nizet V, Palsson BO, Feist AM. PMID: 31471305.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    30. Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis. Nat Commun. 2019 10 11; 10(1):4656. Toledo AG, Golden G, Campos AR, Cuello H, Sorrentino J, Lewis N, Varki N, Nizet V, Smith JW, Esko JD. PMID: 31604940.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    31. Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia. Clin Infect Dis. 2019 09 13; 69(7):1232-1234. Walker MJ, Brouwer S, Forde BM, Worthing KA, McIntyre L, Sundac L, Maloney S, Roberts LW, Barnett TC, Richter J, Cork AJ, Irwin AD, You Y, Zhang J, Dougan G, Yuen KY, Nizet V, Beatson SA, Grimwood K, Davies MR. PMID: 30721938.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    32. Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease. Front Microbiol. 2019; 10:1967. Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Gonzalez DJ, Olson J, Zengler K, Nizet V, Valderrama JA. PMID: 31507572.
      View in: PubMed   Mentions:
    33. PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. Elife. 2019 08 13; 8. Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. PMID: 31408005.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    34. Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens. EBioMedicine. 2019 Aug; 46:193-201. Dillon N, Holland M, Tsunemoto H, Hancock B, Cornax I, Pogliano J, Sakoulas G, Nizet V. PMID: 31353294.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    35. Inflammasome inhibition blocks cardiac glycoside cell toxicity. J Biol Chem. 2019 08 23; 294(34):12846-12854. LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. PMID: 31300552.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    36. Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance. J Infect Dis. 2019 07 02; 220(3):484-493. Ulloa ER, Dillon N, Tsunemoto H, Pogliano J, Sakoulas G, Nizet V. PMID: 30923801.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin. Antimicrob Agents Chemother. 2019 07; 63(7). Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL. PMID: 31235559.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    38. Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli. J Innate Immun. 2019; 11(6):481-495. Patras KA, Ha AD, Rooholfada E, Olson J, Ramachandra Rao SP, Lin AE, Nizet V. PMID: 31055580.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    39. An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model. mBio. 2019 04 30; 10(2). Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. PMID: 31040243.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media. Sci Data. 2019 04 26; 6(1):43. Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, Nizet V, Palsson BO, Feist AM. PMID: 31028276.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    41. Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2019 05; 63(5). Geriak M, Haddad F, Rizvi K, Rose W, Kullar R, LaPlante K, Yu M, Vasina L, Ouellette K, Zervos M, Nizet V, Sakoulas G. PMID: 30858203.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    42. Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion. Front Pharmacol. 2019; 10:323. Meier A, Chien J, Hobohm L, Patras KA, Nizet V, Corriden R. PMID: 31024300.
      View in: PubMed   Mentions:
    43. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019 04 15; 38(8). Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, Rana TM. PMID: 30918008.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    44. Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7465-7470. Uchiyama S, Sun J, Fukahori K, Ando N, Wu M, Schwarz F, Siddiqui SS, Varki A, Marth JD, Nizet V. PMID: 30910970.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    45. Proton-pump inhibitors do not influence clinical outcomes in patients with Staphylococcus aureus bacteremia. Therap Adv Gastroenterol. 2019; 12:1756284819834273. Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G. PMID: 30923573.
      View in: PubMed   Mentions:
    46. Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry. Cell Chem Biol. 2019 05 16; 26(5):724-736.e7. Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS. PMID: 30853419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    47. Impact of Anesthetics on Human Neutrophil Function. Anesth Analg. 2019 03; 128(3):569-574. Meier A, Nizet V. PMID: 30507837.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    48. Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria. Chem Biol Drug Des. 2019 04; 93(4):647-652. Huang YM, Munguia J, Miao Y, Nizet V, McCammon JA. PMID: 30570806.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    49. Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells. Sci Transl Med. 2019 02 06; 11(478). Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, Nizet V, Bothwell M, Brigger M, Crotty S. PMID: 30728285.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ. 2019 03; 26(3):395-408. Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M. PMID: 30622307.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    51. Is a Reported Penicillin Allergy Sufficient Grounds to Forgo the Multidimensional Antimicrobial Benefits of ß-Lactam Antibiotics? Clin Infect Dis. 2019 01 01; 68(1):157-164. Sakoulas G, Geriak M, Nizet V. PMID: 29986019.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection. Toxins (Basel). 2018 12 17; 10(12). Escajadillo T, Nizet V. PMID: 30562923.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    53. The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus. BMC Microbiol. 2018 11 26; 18(1):197. Vrbanac A, Riestra AM, Coady A, Knight R, Nizet V, Patras KA. PMID: 30477439.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    54. Erratum for Schooley et al., "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection". Antimicrob Agents Chemother. 2018 12; 62(12). Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. PMID: 30478181.
      View in: PubMed   Mentions: 4     Fields:    
    55. Tamm-Horsfall Protein Protects the Urinary Tract against Candida albicans. Infect Immun. 2018 12; 86(12). Coady A, Ramos AR, Olson J, Nizet V, Patras KA. PMID: 30297523.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    56. Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages. J Innate Immun. 2019; 11(1):86-98. Riestra AM, Valderrama JA, Patras KA, Booth SD, Quek XY, Tsai CM, Nizet V. PMID: 30391945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    57. Enhanced topical delivery of non-complexed molecular iodine for Methicillin-resistant Staphylococcus aureus decolonization. Int J Pharm. 2019 Jan 10; 554:81-86. Uchiyama S, Dahesh S, Nizet V, Kessler J. PMID: 30395958.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    58. Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. Nat Commun. 2018 10 17; 9(1):4306. Kavvas ES, Catoiu E, Mih N, Yurkovich JT, Seif Y, Dillon N, Heckmann D, Anand A, Yang L, Nizet V, Monk JM, Palsson BO. PMID: 30333483.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    59. Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects. PLoS Pathog. 2018 10; 14(10):e1007348. van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM. PMID: 30321240.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    60. Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis. Cell Host Microbe. 2018 10 10; 24(4):500-513.e5. Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD. PMID: 30308156.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    61. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. J Infect Dis. 2018 10 05; 218(10):1641-1652. Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. PMID: 29868829.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    62. Siglec-7 engagement by GBS ß-protein suppresses pyroptotic cell death of natural killer cells. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10410-10415. Fong JJ, Tsai CM, Saha S, Nizet V, Varki A, Bui JD. PMID: 30254166.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    63. Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors. FEMS Microbiol Rev. 2018 09 01; 42(5):656-671. Askarian F, Wagner T, Johannessen M, Nizet V. PMID: 29893825.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    64. Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera. PLoS Pathog. 2018 06; 14(6):e1007133. Alisson-Silva F, Liu JZ, Diaz SL, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A. PMID: 29912959.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    65. SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity. J Antimicrob Chemother. 2018 06 01; 73(6):1586-1594. Gupta N, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin JH, Nizet V, Corriden R. PMID: 29514266.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    66. Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device. Appl Microbiol Biotechnol. 2018 Aug; 102(15):6459-6467. Kumaraswamy M, Collignon S, Do C, Kim J, Nizet V, Friend J. PMID: 29804135.
      View in: PubMed   Mentions:    Fields:    Translation:CellsPHPublic Health
    67. Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP. Front Cell Infect Microbiol. 2018; 8:160. Soderholm AT, Barnett TC, Korn O, Rivera-Hernandez T, Seymour LM, Schulz BL, Nizet V, Wells CA, Sweet MJ, Walker MJ. PMID: 29868516.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    68. Stabilization of Hypoxia-Inducible Factor-1 Alpha Augments the Therapeutic Capacity of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Pneumonia. Front Med (Lausanne). 2018; 5:131. Gupta N, Nizet V. PMID: 29780805.
      View in: PubMed   Mentions:
    69. Multifactorial inhibition of lactobacilli against the respiratory tract pathogen Moraxella catarrhalis. Benef Microbes. 2018 Apr 25; 9(3):429-439. van den Broek MFL, De Boeck I, Claes IJJ, Nizet V, Lebeer S. PMID: 29633637.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    70. Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit. Front Immunol. 2018; 9:679. Jati S, Kundu S, Chakraborty A, Mahata SK, Nizet V, Sen M. PMID: 29686674.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    71. Humanized Exposures of a ß-Lactam-ß-Lactamase Inhibitor, Tazobactam, versus Non-ß-Lactam-ß-Lactamase Inhibitor, Avibactam, with or without Colistin, against Acinetobacter baumannii in Murine Thigh and Lung Infection Models. Pharmacology. 2018; 101(5-6):255-261. Monogue ML, Sakoulas G, Nizet V, Nicolau DP. PMID: 29533955.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    72. Telavancin for refractory MRSA bacteraemia in intermittent haemodialysis recipients. J Antimicrob Chemother. 2018 03 01; 73(3):764-767. Britt NS, Tirmizi S, Ritchie DJ, Topal JE, McManus D, Nizet V, Casabar E, Sakoulas G. PMID: 29244141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    73. Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches. Front Pediatr. 2018; 6:27. Patras KA, Nizet V. PMID: 29520354.
      View in: PubMed   Mentions:
    74. Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa. Sci Rep. 2018 02 21; 8(1):3437. Haripriyan J, Omanakuttan A, Menon ND, Vanuopadath M, Nair SS, Corriden R, Nair BG, Nizet V, Kumar GB. PMID: 29467483.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    75. Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Front Microbiol. 2018; 9:262. Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. PMID: 29515544.
      View in: PubMed   Mentions:
    76. The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia. Stem Cells. 2018 05; 36(5):796-806. Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. PMID: 29396891.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    77. Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges. Adv Healthc Mater. 2018 07; 7(13):e1701366. Chen Y, Chen M, Zhang Y, Lee JH, Escajadillo T, Gong H, Fang RH, Gao W, Nizet V, Zhang L. PMID: 29436150.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    78. The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis. Microbiol Mol Biol Rev. 2018 06; 82(1). Lawrence SM, Corriden R, Nizet V. PMID: 29436479.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    79. Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance. Sci Rep. 2018 02 02; 8(1):2215. Choe D, Szubin R, Dahesh S, Cho S, Nizet V, Palsson B, Cho BK. PMID: 29396540.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    80. Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus. mBio. 2018 01 30; 9(1). Henningham A, Davies MR, Uchiyama S, van Sorge NM, Lund S, Chen KT, Walker MJ, Cole JN, Nizet V. PMID: 29382733.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    81. Innate Immune Interactions between Bacillus anthracis and Host Neutrophils. Front Cell Infect Microbiol. 2018; 8:2. Liu JZ, Ali SR, Bier E, Nizet V. PMID: 29404280.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    82. Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies. Int J Antimicrob Agents. 2018 Mar; 51(3):468-478. Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V. PMID: 29337066.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    83. Immunoglobulin Attenuates Streptokinase-Mediated Virulence in Streptococcus dysgalactiae Subspecies equisimilis Necrotizing Fasciitis. J Infect Dis. 2018 01 04; 217(2):270-279. Andreoni F, Ugolini F, Keller N, Neff A, Nizet V, Hollands A, Marques Maggio E, Zinkernagel AS, Schuepbach RA. PMID: 29099935.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    84. Modeling neuro-immune interactions during Zika virus infection. Hum Mol Genet. 2018 01 01; 27(1):41-52. Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, de A Zanotto PM, Beltrão-Braga PCB, Nizet V, Muotri AR. PMID: 29048558.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    85. Recurrent infection progressively disables host protection against intestinal inflammation. Science. 2017 12 22; 358(6370). Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD. PMID: 29269445.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    86. Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and ß-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms. Molecules. 2017 Dec 16; 22(12). Catteau L, Reichmann NT, Olson J, Pinho MG, Nizet V, Van Bambeke F, Quetin-Leclercq J. PMID: 29258194.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    87. Group A Streptococcus encounters with host macrophages. Future Microbiol. 2018 01; 13:119-134. Valderrama JA, Nizet V. PMID: 29226710.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    88. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. J Nat Prod. 2018 03 23; 81(3):506-514. Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. PMID: 29215273.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    89. Interaction of Antibiotics with Innate Host Defense Factors against Salmonella enterica Serotype Newport. mSphere. 2017 Nov-Dec; 2(6). Sakoulas G, Kumaraswamy M, Kousha A, Nizet V. PMID: 29242830.
      View in: PubMed   Mentions: 7     Fields:    
    90. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. J Antibiot (Tokyo). 2018 02; 71(2):333-338. Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. PMID: 29184121.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    91. Self-Assembled Colloidal Gel Using Cell Membrane-Coated Nanosponges as Building Blocks. ACS Nano. 2017 12 26; 11(12):11923-11930. Zhang Y, Gao W, Chen Y, Escajadillo T, Ungerleider J, Fang RH, Christman K, Nizet V, Zhang L. PMID: 29116753.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    92. Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11488-11493. Thamphiwatana S, Angsantikul P, Escajadillo T, Zhang Q, Olson J, Luk BT, Zhang S, Fang RH, Gao W, Nizet V, Zhang L. PMID: 29073076.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    93. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. PLoS Pathog. 2017 Sep; 13(9):e1006603. Guichard A, Jain P, Moayeri M, Schwartz R, Chin S, Zhu L, Cruz-Moreno B, Liu JZ, Aguilar B, Hollands A, Leppla SH, Nizet V, Bier E. PMID: 28945820.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    94. Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection. Antimicrob Agents Chemother. 2017 10; 61(10). Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. PMID: 28807909.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    95. Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions. Nat Commun. 2017 09 07; 8(1):477. Sun J, Lei L, Tsai CM, Wang Y, Shi Y, Ouyang M, Lu S, Seong J, Kim TJ, Wang P, Huang M, Xu X, Nizet V, Chien S, Wang Y. PMID: 28883531.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    96. The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance. J Mol Med (Berl). 2017 10; 95(10):1127-1136. Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V. PMID: 28844103.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    97. Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract. Immunol Cell Biol. 2017 11; 95(10):960-965. Patras KA, Coady A, Olson J, Ali SR, RamachandraRao SP, Kumar S, Varki A, Nizet V. PMID: 28829050.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    98. Group A streptococcal M protein activates the NLRP3 inflammasome. Nat Microbiol. 2017 Oct; 2(10):1425-1434. Valderrama JA, Riestra AM, Gao NJ, LaRock CN, Gupta N, Ali SR, Hoffman HM, Ghosh P, Nizet V. PMID: 28784982.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    99. A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus. Front Pharmacol. 2017; 8:477. Escajadillo T, Olson J, Luk BT, Zhang L, Nizet V. PMID: 28769806.
      View in: PubMed   Mentions:
    100. The Accidental Orthodoxy of Drs. Mueller and Hinton. EBioMedicine. 2017 08; 22:26-27. Nizet V. PMID: 28689739.
      View in: PubMed   Mentions: 4     Fields:    
    101. Cathelicidin-deficient mice exhibit increased survival and upregulation of key inflammatory response genes following cecal ligation and puncture. J Mol Med (Berl). 2017 Sep; 95(9):995-1003. Severino P, Ariga SK, Barbeiro HV, de Lima TM, de Paula Silva E, Barbeiro DF, Machado MCC, Nizet V, Pinheiro da Silva F. PMID: 28623379.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    102. Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2017 Jun 12; 2:17107. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. PMID: 28604710.
      View in: PubMed   Mentions:    Fields:    
    103. Increased Endovascular Staphylococcus aureus Inoculum Is the Link Between Elevated Serum Interleukin 10 Concentrations and Mortality in Patients With Bacteremia. Clin Infect Dis. 2017 May 15; 64(10):1406-1412. Rose WE, Shukla SK, Berti AD, Hayney MS, Henriquez KM, Ranzoni A, Cooper MA, Proctor RA, Nizet V, Sakoulas G. PMID: 28205673.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    104. Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation. Blood. 2017 06 08; 129(23):3100-3110. Lizcano A, Secundino I, Döhrmann S, Corriden R, Rohena C, Diaz S, Ghosh P, Deng L, Nizet V, Varki A. PMID: 28416510.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    105. Human milk oligosaccharides inhibit growth of group B Streptococcus. J Biol Chem. 2017 07 07; 292(27):11243-11249. Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. PMID: 28416607.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    106. Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens. Am J Respir Cell Mol Biol. 2017 04; 56(4):423-431. Storisteanu DM, Pocock JM, Cowburn AS, Juss JK, Nadesalingam A, Nizet V, Chilvers ER. PMID: 27854516.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    107. Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs. Trends Pharmacol Sci. 2017 05; 38(5):473-488. Munguia J, Nizet V. PMID: 28283200.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    108. Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil. Front Pediatr. 2017; 5:23. Lawrence SM, Corriden R, Nizet V. PMID: 28293548.
      View in: PubMed   Mentions:
    109. Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2017 03; 61(3). Caffrey AR, Timbrook TT, Noh E, Sakoulas G, Opal SM, Nizet V, LaPlante KL. PMID: 28069650.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    110. Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones. Sci Rep. 2017 02 21; 7:43039. Döhrmann S, LaRock CN, Anderson EL, Cole JN, Ryali B, Stewart C, Nonejuie P, Pogliano J, Corriden R, Ghosh P, Nizet V. PMID: 28220899.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    111. Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. J Immunol. 2017 03 15; 198(6):2366-2373. Okerblom JJ, Schwarz F, Olson J, Fletes W, Ali SR, Martin PT, Glass CK, Nizet V, Varki A. PMID: 28148732.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    112. Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization. mBio. 2017 01 24; 8(1). De Oliveira DM, Hartley-Tassell L, Everest-Dass A, Day CJ, Dabbs RA, Ve T, Kobe B, Nizet V, Packer NH, Walker MJ, Jennings MP, Sanderson-Smith ML. PMID: 28119471.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    113. Classical ß-Lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin against Acinetobacter baumannii. Antimicrob Agents Chemother. 2017 02; 61(2). Sakoulas G, Rose W, Berti A, Olson J, Munguia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V. PMID: 27872080.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    114. Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. EMBO J. 2017 03 15; 36(6):751-760. Schwarz F, Landig CS, Siddiqui S, Secundino I, Olson J, Varki N, Nizet V, Varki A. PMID: 28100677.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    115. Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin a2 as a Host Factor for Bacterial Invasion. mBio. 2017 01 10; 8(1). van Wijk XM, Döhrmann S, Hallström BM, Li S, Voldborg BG, Meng BX, McKee KK, van Kuppevelt TH, Yurchenco PD, Palsson BO, Lewis NE, Nizet V, Esko JD. PMID: 28074024.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    116. Serine-Aspartate Repeat Protein D Increases Staphylococcus aureus Virulence and Survival in Blood. Infect Immun. 2017 Jan; 85(1). Askarian F, Uchiyama S, Valderrama JA, Ajayi C, Sollid JUE, van Sorge NM, Nizet V, van Strijp JAG, Johannessen M. PMID: 27795358.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    117. Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation. PLoS Biol. 2016 Dec; 14(12):e2000631. Sorg RA, Lin L, van Doorn GS, Sorg M, Olson J, Nizet V, Veening JW. PMID: 28027306.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    118. The Selective Estrogen Receptor Modulator Raloxifene Inhibits Neutrophil Extracellular Trap Formation. Front Immunol. 2016; 7:566. Flores R, Döhrmann S, Schaal C, Hakkim A, Nizet V, Corriden R. PMID: 28003814.
      View in: PubMed   Mentions: 5     Fields:    
    119. SAMP-ending down sepsis. Ann Transl Med. 2016 Dec; 4(24):509. Coady A, Nizet V. PMID: 28149871.
      View in: PubMed   Mentions:
    120. Cefazolin and Ertapenem, a Synergistic Combination Used To Clear Persistent Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2016 11; 60(11):6609-6618. Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V. PMID: 27572414.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    121. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2016 Sep 05; 1(11):16155. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. PMID: 27595425.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    122. Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. Cell Host Microbe. 2016 Sep 14; 20(3):307-317. Hentrich K, Löfling J, Pathak A, Nizet V, Varki A, Henriques-Normark B. PMID: 27593514.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    123. IL-1ß is an innate immune sensor of microbial proteolysis. Sci Immunol. 2016 Aug; 1(2). LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. PMID: 28331908.
      View in: PubMed   Mentions: 7     Fields:    
    124. Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):9515-20. Stewart CM, Buffalo CZ, Valderrama JA, Henningham A, Cole JN, Nizet V, Ghosh P. PMID: 27512043.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    125. Conquering Neutrophils. PLoS Pathog. 2016 07; 12(7):e1005682. Döhrmann S, Cole JN, Nizet V. PMID: 27467389.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    126. Alterations in neonatal neutrophil function attributable to increased immature forms. Early Hum Dev. 2016 12; 103:1-7. Makoni M, Eckert J, Anne Pereira H, Nizet V, Lawrence SM. PMID: 27428466.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    127. Evolutionary inactivation of a sialidase in group B Streptococcus. Sci Rep. 2016 06 29; 6:28852. Yamaguchi M, Hirose Y, Nakata M, Uchiyama S, Yamaguchi Y, Goto K, Sumitomo T, Lewis AL, Kawabata S, Nizet V. PMID: 27352769.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    128. Component Analysis of Multipurpose Contact Lens Solutions To Enhance Activity against Pseudomonas aeruginosa and Staphylococcus aureus. Antimicrob Agents Chemother. 2016 07; 60(7):4259-63. Lin L, Kim J, Chen H, Kowalski R, Nizet V. PMID: 27139484.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    129. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. mBio. 2016 06 14; 7(3). Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, Walker MJ. PMID: 27302756.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    130. Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3801-9. Bosi E, Monk JM, Aziz RK, Fondi M, Nizet V, Palsson BØ. PMID: 27286824.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    131. Interleukin-17A Contributes to the Control of Streptococcus pyogenes Colonization and Inflammation of the Female Genital Tract. Sci Rep. 2016 05 31; 6:26836. Carey AJ, Weinberg JB, Dawid SR, Venturini C, Lam AK, Nizet V, Caparon MG, Walker MJ, Watson ME, Ulett GC. PMID: 27241677.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    132. Effects of vancomycin versus nafcillin in enhancing killing of methicillin-susceptible Staphylococcus aureus causing bacteremia by human cathelicidin LL-37. Eur J Clin Microbiol Infect Dis. 2016 Sep; 35(9):1441-7. Le J, Dam Q, Schweizer M, Thienphrapa W, Nizet V, Sakoulas G. PMID: 27234592.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    133. Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils. Biosci Rep. 2016 07; 36(3). Völlger L, Akong-Moore K, Cox L, Goldmann O, Wang Y, Schäfer ST, Naim HY, Nizet V, von Köckritz-Blickwede M. PMID: 27129288.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    134. Molecular dynamic study of MlaC protein in Gram-negative bacteria: conformational flexibility, solvent effect and protein-phospholipid binding. Protein Sci. 2016 08; 25(8):1430-7. Huang YM, Miao Y, Munguia J, Lin L, Nizet V, McCammon JA. PMID: 27111825.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    135. Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. J Biol Chem. 2016 Jul 01; 291(27):13964-73. Hollands A, Corriden R, Gysler G, Dahesh S, Olson J, Raza Ali S, Kunkel MT, Lin AE, Forli S, Newton AC, Kumar GB, Nair BG, Perry JJ, Nizet V. PMID: 27226531.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    136. Interaction of Bacterial Exotoxins with Neutrophil Extracellular Traps: Impact for the Infected Host. Front Microbiol. 2016; 7:402. von Köckritz-Blickwede M, Blodkamp S, Nizet V. PMID: 27064864.
      View in: PubMed   Mentions:
    137. Bacterial Evasion of Host Antimicrobial Peptide Defenses. Microbiol Spectr. 2016 Feb; 4(1). Cole JN, Nizet V. PMID: 26999396.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    138. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. J Antimicrob Chemother. 2016 May; 71(5):1264-9. Kumaraswamy M, Lin L, Olson J, Sun CF, Nonejuie P, Corriden R, Döhrmann S, Ali SR, Amaro D, Rohde M, Pogliano J, Sakoulas G, Nizet V. PMID: 26832758.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    139. Bacterial Cytological Profiling (BCP) as a Rapid and Accurate Antimicrobial Susceptibility Testing Method for Staphylococcus aureus. EBioMedicine. 2016 Feb; 4:95-103. Quach DT, Sakoulas G, Nizet V, Pogliano J, Pogliano K. PMID: 26981574.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    140. Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan. Cell Host Microbe. 2015 Dec 09; 18(6):694-704. Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. PMID: 26651945.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    141. Streptococcal toxins: role in pathogenesis and disease. Cell Microbiol. 2015 Dec; 17(12):1721-41. Barnett TC, Cole JN, Rivera-Hernandez T, Henningham A, Paton JC, Nizet V, Walker MJ. PMID: 26433203.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    142. Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus. Front Immunol. 2015; 6:581. Uchiyama S, Döhrmann S, Timmer AM, Dixit N, Ghochani M, Bhandari T, Timmer JC, Sprague K, Bubeck-Wardenburg J, Simon SI, Nizet V. PMID: 26635795.
      View in: PubMed   Mentions: 14     Fields:    
    143. Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for ß-Lactam-Daptomycin Synergy. Antimicrob Agents Chemother. 2016 01; 60(1):451-8. Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE. PMID: 26525797.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    144. Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing. Cell Host Microbe. 2015 Oct 14; 18(4):471-7. LaRock CN, Döhrmann S, Todd J, Corriden R, Olson J, Johannssen T, Lepenies B, Gallo RL, Ghosh P, Nizet V. PMID: 26468750.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    145. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nat Commun. 2015 Oct 13; 6:8369. Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. PMID: 26458291.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    146. Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14. EMBO J. 2015 Nov 12; 34(22):2775-88. Fong JJ, Sreedhara K, Deng L, Varki NM, Angata T, Liu Q, Nizet V, Varki A. PMID: 26459514.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    147. Inflammasome/IL-1ß Responses to Streptococcal Pathogens. Front Immunol. 2015; 6:518. LaRock CN, Nizet V. PMID: 26500655.
      View in: PubMed   Mentions: 9     Fields:    
    148. Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation. J Mol Med (Berl). 2016 Feb; 94(2):219-33. Secundino I, Lizcano A, Roupé KM, Wang X, Cole JN, Olson J, Ali SR, Dahesh S, Amayreh LK, Henningham A, Varki A, Nizet V. PMID: 26411873.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    149. Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. J Cell Biol. 2015 Sep 28; 210(7):1117-31. Grimsey NJ, Aguilar B, Smith TH, Le P, Soohoo AL, Puthenveedu MA, Nizet V, Trejo J. PMID: 26391660.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    150. Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. PLoS One. 2015; 10(8):e0136605. Pence MA, Haste NM, Meharena HS, Olson J, Gallo RL, Nizet V, Kristian SA. PMID: 26305782.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    151. Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics. Antimicrob Agents Chemother. 2015 Oct; 59(10):6132-9. Sakoulas G, Kumaraswamy M, Nonejuie P, Werth BJ, Rybak MJ, Pogliano J, Rice LB, Nizet V. PMID: 26195528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    152. Stopping superbugs, maintaining the microbiota. Sci Transl Med. 2015 Jul 08; 7(295):295ed8. Nizet V. PMID: 26157027.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    153. Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infect Immun. 2015 Sep; 83(9):3648-56. Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC. PMID: 26150541.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    154. Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus. Chem Biol. 2015 Jun 18; 22(6):785-92. Holden JK, Kang S, Beasley FC, Cinelli MA, Li H, Roy SG, Dejam D, Edinger AL, Nizet V, Silverman RB, Poulos TL. PMID: 26091171.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    155. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens. EBioMedicine. 2015 Jul; 2(7):690-8. Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. PMID: 26288841.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    156. Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase. Chembiochem. 2015 Jul 06; 16(10):1443-7. Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS. PMID: 25930739.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    157. In vitro activity of daptomycin in combination with ß-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci. Antimicrob Agents Chemother. 2015 Jul; 59(7):4279-88. Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R. PMID: 25963982.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    158. Retargeting pre-existing human antibodies to a bacterial pathogen with an alpha-Gal conjugated aptamer. J Mol Med (Berl). 2015 Jun; 93(6):619-31. Kristian SA, Hwang JH, Hall B, Leire E, Iacomini J, Old R, Galili U, Roberts C, Mullis KB, Westby M, Nizet V. PMID: 25940316.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    159. Role of Hypoxia Inducible Factor-1a (HIF-1a) in Innate Defense against Uropathogenic Escherichia coli Infection. PLoS Pathog. 2015 Apr; 11(4):e1004818. Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V. PMID: 25927232.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    160. Analysis of the effects of cigarette smoke on staphylococcal virulence phenotypes. Infect Immun. 2015 Jun; 83(6):2443-52. McEachern EK, Hwang JH, Sladewski KM, Nicatia S, Dewitz C, Mathew DP, Nizet V, Crotty Alexander LE. PMID: 25824841.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    161. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4453-8. Harbut MB, Vilchèze C, Luo X, Hensler ME, Guo H, Yang B, Chatterjee AK, Nizet V, Jacobs WR, Schultz PG, Wang F. PMID: 25831516.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    162. A group A Streptococcus ADP-ribosyltransferase toxin stimulates a protective interleukin 1ß-dependent macrophage immune response. mBio. 2015 Mar 10; 6(2):e00133. Lin AE, Beasley FC, Keller N, Hollands A, Urbano R, Troemel ER, Hoffman HM, Nizet V. PMID: 25759502.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    163. Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1a. Immunity. 2015 Mar 17; 42(3):484-98. Shalova IN, Lim JY, Chittezhath M, Zinkernagel AS, Beasley F, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Rapisarda A, Chen J, Duan K, Yang H, Poidinger M, Melillo G, Nizet V, Arnalich F, López-Collazo E, Biswas SK. PMID: 25746953.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    164. Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics. Antimicrob Agents Chemother. 2015 May; 59(5):2799-806. Berti AD, Baines SL, Howden BP, Sakoulas G, Nizet V, Proctor RA, Rose WE. PMID: 25733508.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    165. Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. J Immunol. 2015 Apr 01; 194(7):3259-66. Matak P, Heinis M, Mathieu JR, Corriden R, Cuvellier S, Delga S, Mounier R, Rouquette A, Raymond J, Lamarque D, Emile JF, Nizet V, Touati E, Peyssonnaux C. PMID: 25710915.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    166. Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens. Biochim Biophys Acta. 2015 Nov; 1848(11 Pt B):3047-54. LaRock CN, Nizet V. PMID: 25701232.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    167. Hedgehog: linking uracil to innate defense. Cell Host Microbe. 2015 Feb 11; 17(2):146-8. Bier E, Nizet V. PMID: 25674980.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    168. Mechanisms of group A Streptococcus resistance to reactive oxygen species. FEMS Microbiol Rev. 2015 Jul; 39(4):488-508. Henningham A, Döhrmann S, Nizet V, Cole JN. PMID: 25670736.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    169. The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-?B signaling, and inflammatory gene expression in human aortic valve cells. FASEB J. 2015 May; 29(5):1859-68. Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. PMID: 25630970.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    170. Examining the use of ceftaroline in the treatment of Streptococcus pneumoniae meningitis with reference to human cathelicidin LL-37. Antimicrob Agents Chemother. 2015 Apr; 59(4):2428-31. Sakoulas G, Nonejuie P, Kullar R, Pogliano J, Rybak MJ, Nizet V. PMID: 25605351.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    171. Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy. Mol Cell. 2015 Jan 08; 57(1):55-68. Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M. PMID: 25544559.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    172. Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. Eur J Med Chem. 2015 Jan 27; 90:448-61. Kang S, Watanabe M, Jacobs JC, Yamaguchi M, Dahesh S, Nizet V, Leyh TS, Silverman RB. PMID: 25461893.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    173. N-terminal ArgD peptides from the classical Staphylococcus aureus Agr system have cytotoxic and proinflammatory activities. Chem Biol. 2014 Nov 20; 21(11):1457-62. Gonzalez DJ, Corriden R, Akong-Moore K, Olson J, Dorrestein PC, Nizet V. PMID: 25457179.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    174. The antimicrobial peptide LL-37 facilitates the formation of neutrophil extracellular traps. Biochem J. 2014 Nov 15; 464(1):3-11. Neumann A, Berends ET, Nerlich A, Molhoek EM, Gallo RL, Meerloo T, Nizet V, Naim HY, von Köckritz-Blickwede M. PMID: 25181554.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    175. HIF transcription factors, inflammation, and immunity. Immunity. 2014 Oct 16; 41(4):518-28. Palazon A, Goldrath AW, Nizet V, Johnson RS. PMID: 25367569.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    176. Mutual exclusivity of hyaluronan and hyaluronidase in invasive group A Streptococcus. J Biol Chem. 2014 Nov 14; 289(46):32303-15. Henningham A, Yamaguchi M, Aziz RK, Kuipers K, Buffalo CZ, Dahesh S, Choudhury B, Van Vleet J, Yamaguchi Y, Seymour LM, Ben Zakour NL, He L, Smith HV, Grimwood K, Beatson SA, Ghosh P, Walker MJ, Nizet V, Cole JN. PMID: 25266727.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    177. RAB11-mediated trafficking in host-pathogen interactions. Nat Rev Microbiol. 2014 Sep; 12(9):624-34. Guichard A, Nizet V, Bier E. PMID: 25118884.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    178. Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. J Mol Med (Berl). 2014 Dec; 92(12):1305-17. Vega VL, Crotty Alexander LE, Charles W, Hwang JH, Nizet V, De Maio A. PMID: 25163764.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    179. Hyaluronan breakdown contributes to immune defense against group A Streptococcus. J Biol Chem. 2014 Sep 26; 289(39):26914-21. Schommer NN, Muto J, Nizet V, Gallo RL. PMID: 25122767.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    180. Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria. ChemMedChem. 2014 Sep; 9(9):2164-71. Fair RJ, McCoy LS, Hensler ME, Aguilar B, Nizet V, Tor Y. PMID: 25055981.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    181. Role for streptococcal collagen-like protein 1 in M1T1 group A Streptococcus resistance to neutrophil extracellular traps. Infect Immun. 2014 Oct; 82(10):4011-20. Döhrmann S, Anik S, Olson J, Anderson EL, Etesami N, No H, Snipper J, Nizet V, Okumura CY. PMID: 25024366.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    182. Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline. Clin Ther. 2014 Oct 01; 36(10):1317-33. Sakoulas G, Moise PA, Casapao AM, Nonejuie P, Olson J, Okumura CY, Rybak MJ, Kullar R, Dhand A, Rose WE, Goff DA, Bressler AM, Lee Y, Pogliano J, Johns S, Kaatz GW, Ebright JR, Nizet V. PMID: 25017183.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    183. Novel role of the antimicrobial peptide LL-37 in the protection of neutrophil extracellular traps against degradation by bacterial nucleases. J Innate Immun. 2014; 6(6):860-8. Neumann A, Völlger L, Berends ET, Molhoek EM, Stapels DA, Midon M, Friães A, Pingoud A, Rooijakkers SH, Gallo RL, Mörgelin M, Nizet V, Naim HY, von Köckritz-Blickwede M. PMID: 25012862.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    184. The interplay between Siglecs and sialylated pathogens. Glycobiology. 2014 Sep; 24(9):818-25. Chang YC, Nizet V. PMID: 24996821.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    185. Hypoxia-Inducible Factor (HIF) as a Pharmacological Target for Prevention and Treatment of Infectious Diseases. Infect Dis Ther. 2014 Dec; 3(2):159-74. Bhandari T, Nizet V. PMID: 25134687.
      View in: PubMed   Mentions:
    186. Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens. Annu Rev Microbiol. 2014; 68:439-58. Okumura CY, Nizet V. PMID: 25002085.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    187. The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host Microbe. 2014 Jun 11; 15(6):729-740. van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ETM, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L, Gin J, Cunningham M, Merriman JA, Hütter J, Lepenies B, Rooijakkers SHM, Malley R, Walker MJ, Shattil SJ, Schlievert PM, Choudhury B, Nizet V. PMID: 24922575.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    188. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. J Exp Med. 2014 Jun 02; 211(6):1231-42. Ali SR, Fong JJ, Carlin AF, Busch TD, Linden R, Angata T, Areschoug T, Parast M, Varki N, Murray J, Nizet V, Varki A. PMID: 24799499.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    189. Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus. J Mol Med (Berl). 2014 Sep; 92(9):951-9. Chang YC, Olson J, Louie A, Crocker PR, Varki A, Nizet V. PMID: 24788876.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    190. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III). Mar Drugs. 2014 Apr 30; 12(5):2458-70. Liu Y, Haste NM, Thienphrapa W, Li J, Nizet V, Hensler M, Li R. PMID: 24796304.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    191. Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2014 Aug; 67(8):549-53. Hensler ME, Jang KH, Thienphrapa W, Vuong L, Tran DN, Soubih E, Lin L, Haste NM, Cunningham ML, Kwan BP, Shaw KJ, Fenical W, Nizet V. PMID: 24736856.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    192. Disease manifestations and pathogenic mechanisms of Group A Streptococcus. Clin Microbiol Rev. 2014 Apr; 27(2):264-301. Walker MJ, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V. PMID: 24696436.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansAnimalsCells
    193. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5520-5. Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. PMID: 24706917.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    194. Human cathelicidin LL-37 resistance and increased daptomycin MIC in methicillin-resistant Staphylococcus aureus strain USA600 (ST45) are associated with increased mortality in a hospital setting. J Clin Microbiol. 2014 Jun; 52(6):2172-4. Sakoulas G, Guram K, Reyes K, Nizet V, Zervos M. PMID: 24648548.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    195. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Mol Cell Proteomics. 2014 May; 13(5):1262-72. Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. PMID: 24567418.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    196. Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-?. PLoS One. 2014; 9(2):e89284. Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK. PMID: 24586659.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    197. Transcription factor binding site analysis identifies FOXO transcription factors as regulators of the cutaneous wound healing process. PLoS One. 2014; 9(2):e89274. Roupé KM, Veerla S, Olson J, Stone EL, Sørensen OE, Hedrick SM, Nizet V. PMID: 24586650.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    198. Participatory medicine: a home score for streptococcal pharyngitis. Ann Intern Med. 2014 Feb 18; 160(4):289. Fine AM, Nizet V, Mandl KD. PMID: 24534928.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    199. Group B Streptococcus ß-hemolysin/cytolysin breaches maternal-fetal barriers to cause preterm birth and intrauterine fetal demise in vivo. J Infect Dis. 2014 Jul 15; 210(2):265-73. Randis TM, Gelber SE, Hooven TA, Abellar RG, Akabas LH, Lewis EL, Walker LB, Byland LM, Nizet V, Ratner AJ. PMID: 24474814.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    200. A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-?B signaling. J Innate Immun. 2014; 6(4):485-98. Askarian F, van Sorge NM, Sangvik M, Beasley FC, Henriksen JR, Sollid JU, van Strijp JA, Nizet V, Johannessen M. PMID: 24481289.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    201. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1957-62. Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. PMID: 24449899.
      View in: PubMed   Mentions: 100     Fields:    Translation:Cells
    202. Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo. PLoS Pathog. 2014 Jan; 10(1):e1003846. Chang YC, Olson J, Beasley FC, Tung C, Zhang J, Crocker PR, Varki A, Nizet V. PMID: 24391502.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    203. Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection. PLoS One. 2013; 8(12):e84481. Crotty Alexander LE, Marsh BJ, Timmer AM, Lin AE, Zainabadi K, Czopik A, Guarente L, Nizet V. PMID: 24386389.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    204. Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis. Infect Immun. 2014 Mar; 82(3):1132-40. Franks SE, Ebrahimi C, Hollands A, Okumura CY, Aroian RV, Nizet V, McGillivray SM. PMID: 24366250.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    205. Ceftaroline restores daptomycin activity against daptomycin-nonsusceptible vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2014; 58(3):1494-500. Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V. PMID: 24366742.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    206. The fibrinogen-binding M1 protein reduces pharyngeal cell adherence and colonization phenotypes of M1T1 group A Streptococcus. J Biol Chem. 2014 Feb 07; 289(6):3539-46. Anderson EL, Cole JN, Olson J, Ryba B, Ghosh P, Nizet V. PMID: 24356958.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    207. The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication. Cell Host Microbe. 2013 Dec 11; 14(6):675-82. Barnett TC, Liebl D, Seymour LM, Gillen CM, Lim JY, Larock CN, Davies MR, Schulz BL, Nizet V, Teasdale RD, Walker MJ. PMID: 24331465.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    208. Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates. FASEB J. 2014 Mar; 28(3):1280-93. Padler-Karavani V, Hurtado-Ziola N, Chang YC, Sonnenburg JL, Ronaghy A, Yu H, Verhagen A, Nizet V, Chen X, Varki N, Varki A, Angata T. PMID: 24308974.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    209. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. J Mol Med (Berl). 2014 Feb; 92(2):139-49. Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V. PMID: 24297496.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    210. Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20218-23. Grewal PK, Aziz PV, Uchiyama S, Rubio GR, Lardone RD, Le D, Varki NM, Nizet V, Marth JD. PMID: 24284176.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    211. Participatory medicine: A home score for streptococcal pharyngitis enabled by real-time biosurveillance: a cohort study. Ann Intern Med. 2013 Nov 05; 159(9):577-83. Fine AM, Nizet V, Mandl KD. PMID: 24189592.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    212. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4407-16. Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. PMID: 24191063.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    213. Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity. PLoS One. 2013; 8(10):e77282. Yamaguchi M, Terao Y, Mori-Yamaguchi Y, Domon H, Sakaue Y, Yagi T, Nishino K, Yamaguchi A, Nizet V, Kawabata S. PMID: 24194877.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    214. HIF isoforms in the skin differentially regulate systemic arterial pressure. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17570-5. Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. PMID: 24101470.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    215. EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and a1-acid glycoprotein. Biochem J. 2013 Oct 01; 455(1):107-18. Sjögren J, Struwe WB, Cosgrave EF, Rudd PM, Stervander M, Allhorn M, Hollands A, Nizet V, Collin M. PMID: 23865566.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    216. Epidermal deletion of HIF-2a stimulates wound closure. J Invest Dermatol. 2014 Mar; 134(3):801-808. Cowburn AS, Alexander LEC, Southwood M, Nizet V, Chilvers ER, Johnson RS. PMID: 24037341.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    217. Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions. Cell Host Microbe. 2013 Sep 11; 14(3):294-305. Guichard A, Cruz-Moreno B, Cruz-Moreno BC, Aguilar B, van Sorge NM, Kuang J, Kurkciyan AA, Wang Z, Hang S, Pineton de Chambrun GP, McCole DF, Watnick P, Nizet V, Bier E. PMID: 24034615.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    218. Human milk oligosaccharides protect bladder epithelial cells against uropathogenic Escherichia coli invasion and cytotoxicity. J Infect Dis. 2014 Feb 01; 209(3):389-98. Lin AE, Autran CA, Espanola SD, Bode L, Nizet V. PMID: 23990566.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    219. Neuroscience: Bacteria get on your nerves. Nature. 2013 Sep 05; 501(7465):43-4. Nizet V, Yaksh T. PMID: 23965630.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    220. Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. J Innate Immun. 2014; 6(2):240-50. Ly D, Taylor JM, Tsatsaronis JA, Monteleone MM, Skora AS, Donald CA, Maddocks T, Nizet V, West NP, Ranson M, Walker MJ, McArthur JD, Sanderson-Smith ML. PMID: 23969887.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    221. Role of hypoxia inducible factor-1 in keratinocyte inflammatory response and neutrophil recruitment. J Inflamm (Lond). 2013 Aug 10; 10(1):28. Leire E, Olson J, Isaacs H, Nizet V, Hollands A. PMID: 23937964.
      View in: PubMed   Mentions:
    222. IgG protease Mac/IdeS is not essential for phagocyte resistance or mouse virulence of M1T1 group A Streptococcus. mBio. 2013 Jul 30; 4(4). Okumura CY, Anderson EL, Döhrmann S, Tran DN, Olson J, von Pawel-Rammingen U, Nizet V. PMID: 23900173.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    223. ß-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct; 57(10):5005-12. Berti AD, Sakoulas G, Nizet V, Tewhey R, Rose WE. PMID: 23896478.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    224. A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection. PLoS Pathog. 2013; 9(7):e1003469. Sanderson-Smith ML, Zhang Y, Ly D, Donahue D, Hollands A, Nizet V, Ranson M, Ploplis VA, Walker MJ, Castellino FJ. PMID: 23853591.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    225. Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. EMBO Rep. 2013 Aug; 14(8):726-32. Corriden R, Self T, Akong-Moore K, Nizet V, Kellam B, Briddon SJ, Hill SJ. PMID: 23817552.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    226. Treatment of high-level gentamicin-resistant Enterococcus faecalis endocarditis with daptomycin plus ceftaroline. Antimicrob Agents Chemother. 2013 Aug; 57(8):4042-5. Sakoulas G, Nonejuie P, Nizet V, Pogliano J, Crum-Cianflone N, Haddad F. PMID: 23689728.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    227. HIF-1a influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination. J Mol Med (Berl). 2013 Oct; 91(10):1199-205. Bhandari T, Olson J, Johnson RS, Nizet V. PMID: 23686259.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    228. Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus. FASEB J. 2013 Jul; 27(7):2633-43. Tsatsaronis JA, Hollands A, Cole JN, Maamary PG, Gillen CM, Ben Zakour NL, Kotb M, Nizet V, Beatson SA, Walker MJ, Sanderson-Smith ML. PMID: 23531597.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    229. Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370. Infect Immun. 2013 Jun; 81(6):2062-9. Venturini C, Ong CL, Gillen CM, Ben-Zakour NL, Maamary PG, Nizet V, Beatson SA, Walker MJ. PMID: 23529618.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    230. Succinate is an inflammatory signal that induces IL-1ß through HIF-1a. Nature. 2013 Apr 11; 496(7444):238-42. Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA. PMID: 23535595.
      View in: PubMed   Mentions: 619     Fields:    Translation:HumansAnimalsCells
    231. Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation. Cell Mol Life Sci. 2013 Sep; 70(17):3199-210. Angata T, Ishii T, Motegi T, Oka R, Taylor RE, Soto PC, Chang YC, Secundino I, Gao CX, Ohtsubo K, Kitazume S, Nizet V, Varki A, Gemma A, Kida K, Taniguchi N. PMID: 23519826.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    232. Severe soft tissue infection caused by a non-beta-hemolytic Streptococcus pyogenes strain harboring a premature stop mutation in the sagC gene. J Clin Microbiol. 2013 Jun; 51(6):1962-5. Jantsch J, Gerlach RG, Ensser A, Dahesh S, Popp I, Heeg C, Bleiziffer O, Merz T, Schulz T, Horch RE, Bogdan C, Nizet V, van der Linden M. PMID: 23515542.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    233. Coiled-coil irregularities of the M1 protein structure promote M1-fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence. J Mol Med (Berl). 2013 Jul; 91(7):861-9. Uchiyama S, Andreoni F, Zürcher C, Schilcher K, Ender M, Madon J, Matt U, Ghosh P, Nizet V, Schuepbach RA, Zinkernagel AS. PMID: 23443671.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    234. Hypoxia potentiates allergen induction of HIF-1a, chemokines, airway inflammation, TGF-ß1, and airway remodeling in a mouse model. Clin Immunol. 2013 Apr; 147(1):27-37. Baek KJ, Cho JY, Rosenthal P, Alexander LEC, Nizet V, Broide DH. PMID: 23499929.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    235. Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development. J Biol Chem. 2013 Mar 01; 288(9):6417-26. van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. PMID: 23322784.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    236. Myeloid cell HIF-1a regulates asthma airway resistance and eosinophil function. J Mol Med (Berl). 2013 May; 91(5):637-44. Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H, Johnson RS, Broide DH, Nizet V. PMID: 23250618.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    237. Antibacterial drug leads targeting isoprenoid biosynthesis. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):123-8. Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, Nizet V, McCammon JA, Oldfield E. PMID: 23248302.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    238. Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection. PLoS Genet. 2012; 8(10):e1003007. Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. PMID: 23093945.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    239. Study of streptococcal hemoprotein receptor (Shr) in iron acquisition and virulence of M1T1 group A streptococcus. Virulence. 2012 Nov 15; 3(7):566-75. Dahesh S, Nizet V, Cole JN. PMID: 23076332.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    240. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2012 Dec; 65(12):593-8. Haste NM, Thienphrapa W, Tran DN, Loesgen S, Sun P, Nam SJ, Jensen PR, Fenical W, Sakoulas G, Nizet V, Hensler ME. PMID: 23047246.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    241. A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides. J Biol Chem. 2012 Nov 30; 287(49):40891-7. Hollands A, Gonzalez D, Leire E, Donald C, Gallo RL, Sanderson-Smith M, Dorrestein PC, Nizet V. PMID: 23038245.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    242. Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia. J Infect Dis. 2012 Nov 15; 206(10):1604-11. Rose WE, Eickhoff JC, Shukla SK, Pantrangi M, Rooijakkers S, Cosgrove SE, Nizet V, Sakoulas G. PMID: 22966128.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    243. A conserved UDP-glucose dehydrogenase encoded outside the hasABC operon contributes to capsule biogenesis in group A Streptococcus. J Bacteriol. 2012 Nov; 194(22):6154-61. Cole JN, Aziz RK, Kuipers K, Timmer AM, Nizet V, van Sorge NM. PMID: 22961854.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    244. Genotypic and phenotypic evaluation of the evolution of high-level daptomycin nonsusceptibility in vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012 Nov; 56(11):6051-3. Humphries RM, Kelesidis T, Tewhey R, Rose WE, Schork N, Nizet V, Sakoulas G. PMID: 22948885.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    245. A novel role for the transcription factor HIF-1a in the formation of mast cell extracellular traps. Biochem J. 2012 Aug 15; 446(1):159-63. Branitzki-Heinemann K, Okumura CY, Völlger L, Kawakami Y, Kawakami T, Naim HY, Nizet V, Von Köckritz-Blickwede M. PMID: 22738198.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    246. Influences of chloride and hypochlorite on neutrophil extracellular trap formation. PLoS One. 2012; 7(8):e42984. Akong-Moore K, Chow OA, von Köckritz-Blickwede M, Nizet V. PMID: 22912772.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    247. Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB J. 2012 Nov; 26(11):4675-84. Maamary PG, Ben Zakour NL, Cole JN, Hollands A, Aziz RK, Barnett TC, Cork AJ, Henningham A, Sanderson-Smith M, McArthur JD, Venturini C, Gillen CM, Kirk JK, Johnson DR, Taylor WL, Kaplan EL, Kotb M, Nizet V, Beatson SA, Walker MJ. PMID: 22878963.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    248. The pore-forming toxin ß hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. PLoS Pathog. 2012; 8(7):e1002812. Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T. PMID: 22829768.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    249. DNase Sda1 allows invasive M1T1 Group A Streptococcus to prevent TLR9-dependent recognition. PLoS Pathog. 2012; 8(6):e1002736. Uchiyama S, Andreoni F, Schuepbach RA, Nizet V, Zinkernagel AS. PMID: 22719247.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    250. Large-scale validation of the Centor and McIsaac scores to predict group A streptococcal pharyngitis. Arch Intern Med. 2012 Jun 11; 172(11):847-52. Fine AM, Nizet V, Mandl KD. PMID: 22566485.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    251. Specific inactivation of two immunomodulatory SIGLEC genes during human evolution. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9935-40. Wang X, Mitra N, Secundino I, Banda K, Cruz P, Padler-Karavani V, Verhagen A, Reid C, Lari M, Rizzi E, Balsamo C, Corti G, De Bellis G, Longo L, Beggs W, Caramelli D, Tishkoff SA, Hayakawa T, Green ED, Mullikin JC, Nizet V, Bui J, Varki A. PMID: 22665810.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    252. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. J Proteomics. 2012 Aug 30; 75(16):5069-5076. Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, Dorrestein PC. PMID: 22641157.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    253. Selectively guanidinylated aminoglycosides as antibiotics. ChemMedChem. 2012 Jul; 7(7):1237-44. Fair RJ, Hensler ME, Thienphrapa W, Dam QN, Nizet V, Tor Y. PMID: 22639134.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    254. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chem Biol. 2012 May 25; 19(5):559-71. van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. PMID: 22633408.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    255. Endoplasmic reticulum protein BI-1 regulates Ca²?-mediated bioenergetics to promote autophagy. Genes Dev. 2012 May 15; 26(10):1041-54. Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC. PMID: 22588718.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    256. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I). Mar Drugs. 2012 Apr; 10(4):953-62. Liu Y, Haste NM, Thienphrapa W, Nizet V, Hensler M, Li R. PMID: 22690153.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    257. Conserved anchorless surface proteins as group A streptococcal vaccine candidates. J Mol Med (Berl). 2012 Oct; 90(10):1197-207. Henningham A, Chiarot E, Gillen CM, Cole JN, Rohde M, Fulde M, Ramachandran V, Cork AJ, Hartas J, Magor G, Djordjevic SP, Cordwell SJ, Kobe B, Sriprakash KS, Nizet V, Chhatwal GS, Margarit IY, Batzloff MR, Walker MJ. PMID: 22527883.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    258. Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile. PLoS One. 2012; 7(4):e35218. Hertzén E, Johansson L, Kansal R, Hecht A, Dahesh S, Janos M, Nizet V, Kotb M, Norrby-Teglund A. PMID: 22511985.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    259. HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. ACS Med Chem Lett. 2012 Apr 03; 3(5):402-406. Zhang Y, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, Oldfield E. PMID: 22662288.
      View in: PubMed   Mentions:
    260. Cofactors required for TLR7- and TLR9-dependent innate immune responses. Cell Host Microbe. 2012 Mar 15; 11(3):306-18. Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK. PMID: 22423970.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    261. A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection. J Mol Med (Berl). 2012 Sep; 90(9):1079-89. Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. PMID: 22371073.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    262. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98. Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. PMID: 22371493.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    263. Staphylococcus aureus virulence is enhanced by secreted factors that block innate immune defenses. J Innate Immun. 2012; 4(3):301-11. Jongerius I, von Köckritz-Blickwede M, Horsburgh MJ, Ruyken M, Nizet V, Rooijakkers SH. PMID: 22327617.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    264. Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. ChemMedChem. 2012 Apr; 7(4):561-4. Lin FY, Zhang Y, Hensler M, Liu YL, Chow OA, Zhu W, Wang K, Pang R, Thienphrapa W, Nizet V, Oldfield E. PMID: 22290830.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    265. Novel bacterial metabolite merochlorin A demonstrates in vitro activity against multi-drug resistant methicillin-resistant Staphylococcus aureus. PLoS One. 2012; 7(1):e29439. Sakoulas G, Nam SJ, Loesgen S, Fenical W, Jensen PR, Nizet V, Hensler M. PMID: 22279537.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    266. Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics. Antimicrob Agents Chemother. 2012 Apr; 56(4):1854-61. McGillivray SM, Tran DN, Ramadoss NS, Alumasa JN, Okumura CY, Sakoulas G, Vaughn MM, Zhang DX, Keiler KC, Nizet V. PMID: 22252821.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    267. Leukocyte inflammatory responses provoked by pneumococcal sialidase. mBio. 2012; 3(1). Chang YC, Uchiyama S, Varki A, Nizet V. PMID: 22215570.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    268. The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One. 2011; 6(12):e29122. Kho MF, Bellier A, Balasubramani V, Hu Y, Hsu W, Nielsen-LeRoux C, McGillivray SM, Nizet V, Aroian RV. PMID: 22216181.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    269. Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2012 Feb; 56(2):838-44. Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA. PMID: 22123698.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    270. Improved diagnostic accuracy of group A streptococcal pharyngitis with use of real-time biosurveillance. Ann Intern Med. 2011 Sep 20; 155(6):345-52. Fine AM, Nizet V, Mandl KD. PMID: 21930851.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    271. Molecular insight into invasive group A streptococcal disease. Nat Rev Microbiol. 2011 Sep 16; 9(10):724-36. Cole JN, Barnett TC, Nizet V, Walker MJ. PMID: 21921933.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
    272. New insights into the biological effects of anthrax toxins: linking cellular to organismal responses. Microbes Infect. 2012 Feb; 14(2):97-118. Guichard A, Nizet V, Bier E. PMID: 21930233.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    273. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat Immunol. 2011 Sep 04; 12(10):966-74. Kinjo Y, Illarionov P, Vela JL, Pei B, Girardi E, Li X, Li Y, Imamura M, Kaneko Y, Okawara A, Miyazaki Y, Gómez-Velasco A, Rogers P, Dahesh S, Uchiyama S, Khurana A, Kawahara K, Yesilkaya H, Andrew PW, Wong CH, Kawakami K, Nizet V, Besra GS, Tsuji M, Zajonc DM, Kronenberg M. PMID: 21892173.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    274. Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. J Innate Immun. 2012; 4(2):213-8. Zinkernagel AS, Hruz P, Uchiyama S, von Köckritz-Blickwede M, Schuepbach RA, Hayashi T, Carson DA, Nizet V. PMID: 21860217.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    275. A randomized controlled trial of motavizumab versus palivizumab for the prophylaxis of serious respiratory syncytial virus disease in children with hemodynamically significant congenital heart disease. Pediatr Res. 2011 Aug; 70(2):186-91. Feltes TF, Sondheimer HM, Tulloh RM, Harris BS, Jensen KM, Losonsky GA, Griffin MP. PMID: 21522037.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    276. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein. J Biol Chem. 2011 Sep 30; 286(39):33981-91. Nordström T, Movert E, Olin AI, Ali SR, Nizet V, Varki A, Areschoug T. PMID: 21795693.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    277. Use of antistaphylococcal beta-lactams to increase daptomycin activity in eradicating persistent bacteremia due to methicillin-resistant Staphylococcus aureus: role of enhanced daptomycin binding. Clin Infect Dis. 2011 Jul 15; 53(2):158-63. Dhand A, Bayer AS, Pogliano J, Yang SJ, Bolaris M, Nizet V, Wang G, Sakoulas G. PMID: 21690622.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    278. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology. 2011 Sep; 157(Pt 9):2485-2492. Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. PMID: 21719540.
      View in: PubMed   Mentions:
    279. Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp. Bioorg Med Chem. 2011 Nov 15; 19(22):6557-62. Sun P, Maloney KN, Nam SJ, Haste NM, Raju R, Aalbersberg W, Jensen PR, Nizet V, Hensler ME, Fenical W. PMID: 21745747.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    280. Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems. PLoS Pathog. 2011 Jun; 7(6):e1002082. Chang YC, Wang Z, Flax LA, Xu D, Esko JD, Nizet V, Baron MJ. PMID: 21731486.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    281. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 2011 Jul 22; 35(1):34-44. Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. PMID: 21683629.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    282. Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Dev Comp Immunol. 2012 Jan; 36(1):31-8. Carland TM, Locke JB, Nizet V, Gerwick L. PMID: 21683091.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    283. Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence. BMC Microbiol. 2011 May 27; 11:120. Sjögren J, Okumura CY, Collin M, Nizet V, Hollands A. PMID: 21619648.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    284. The FbaB-type fibronectin-binding protein of Streptococcus pyogenes promotes specific invasion into endothelial cells. Cell Microbiol. 2011 Aug; 13(8):1200-11. Amelung S, Nerlich A, Rohde M, Spellerberg B, Cole JN, Nizet V, Chhatwal GS, Talay SR. PMID: 21615663.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    285. Total synthesis and biological evaluation of marinopyrrole A and analogues. Tetrahedron Lett. 2011 Apr 27; 52(17):2041-2043. Nicolaou KC, Simmons NL, Chen JS, Haste NM, Nizet V. PMID: 21499535.
      View in: PubMed   Mentions: 8     Fields:    
    286. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus. Mar Drugs. 2011; 9(4):680-9. Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. PMID: 21731557.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    287. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2011 Jul; 55(7):3305-12. Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. PMID: 21502631.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    288. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl). 2011 Oct; 89(10):997-1013. Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. PMID: 21499735.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    289. Streptococcal M1 protein constructs a pathological host fibrinogen network. Nature. 2011 Apr 07; 472(7341):64-8. Macheboeuf P, Buffalo C, Fu CY, Zinkernagel AS, Cole JN, Johnson JE, Nizet V, Ghosh P. PMID: 21475196.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    290. Papillation in Bacillus anthracis colonies: a tool for finding new mutators. Mol Microbiol. 2011 Mar; 79(5):1276-93. Yang H, Sikavi C, Tran K, McGillivray SM, Nizet V, Yung M, Chang A, Miller JH. PMID: 21205011.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    291. Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis. 2011 Feb 01; 203(3):393-400. Reiss A, Braun JS, Jäger K, Freyer D, Laube G, Bührer C, Felderhoff-Müser U, Stadelmann C, Nizet V, Weber JR. PMID: 21186256.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    292. IL-1ß-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKß. Nat Immunol. 2011 Feb; 12(2):144-50. Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. PMID: 21170027.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    293. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010 Nov 18; 8(5):445-54. Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. PMID: 21075355.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    294. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. Nature. 2010 Oct 14; 467(7317):854-8. Guichard A, McGillivray SM, Cruz-Moreno B, van Sorge NM, Nizet V, Bier E. PMID: 20944747.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    295. Bacteria and phagocytes: mortal enemies. J Innate Immun. 2010; 2(6):505-7. Nizet V. PMID: 20829606.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    296. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J Innate Immun. 2010; 2(6):576-86. Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, von Köckritz-Blickwede M. PMID: 20829609.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    297. Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. J Innate Immun. 2010; 2(6):596-606. Maamary PG, Sanderson-Smith ML, Aziz RK, Hollands A, Cole JN, McKay FC, McArthur JD, Kirk JK, Cork AJ, Keefe RJ, Kansal RG, Sun H, Taylor WL, Chhatwal GS, Ginsburg D, Nizet V, Kotb M, Walker MJ. PMID: 20814186.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    298. Streptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A Streptococcus. J Innate Immun. 2010; 2(6):587-95. Pence MA, Rooijakkers SH, Cogen AL, Cole JN, Hollands A, Gallo RL, Nizet V. PMID: 20814187.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    299. M protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus. mBio. 2010 Aug 31; 1(4). Cole JN, Pence MA, von Köckritz-Blickwede M, Hollands A, Gallo RL, Walker MJ, Nizet V. PMID: 20827373.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    300. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16286-90. Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. PMID: 20805502.
      View in: PubMed   Mentions: 75     Fields:    Translation:Cells
    301. On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity. Bioorg Med Chem Lett. 2010 Oct 01; 20(19):5701-4. Derbal S, Hensler M, Fang W, Nizet V, Ghedira K, Nefzi A. PMID: 20800485.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    302. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010 Jul 23; 5(7):e11701. Zhao HW, Zhou D, Nizet V, Haddad GG. PMID: 20668515.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    303. Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid. J Exp Med. 2010 Aug 02; 207(8):1637-46. Taylor RE, Gregg CJ, Padler-Karavani V, Ghaderi D, Yu H, Huang S, Sorensen RU, Chen X, Inostroza J, Nizet V, Varki A. PMID: 20624889.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    304. Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem. 2010 Sep 03; 285(36):27609-13. Rooijakkers SH, Rasmussen SL, McGillivray SM, Bartnikas TB, Mason AB, Friedlander AM, Nizet V. PMID: 20615872.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    305. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. J Infect Dis. 2010 Jul 01; 202(1):11-9. Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, Walker MJ, Nizet V. PMID: 20507231.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    306. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. PMID: 20581111.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    307. The CXC chemokine-degrading protease SpyCep of Streptococcus pyogenes promotes its uptake into endothelial cells. J Biol Chem. 2010 Sep 03; 285(36):27798-805. Kaur SJ, Nerlich A, Bergmann S, Rohde M, Fulde M, Zähner D, Hanski E, Zinkernagel A, Nizet V, Chhatwal GS, Talay SR. PMID: 20562101.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    308. O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. Biochem J. 2010 May 13; 428(2):163-8. Weiman S, Uchiyama S, Lin FY, Chaffin D, Varki A, Nizet V, Lewis AL. PMID: 20334627.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    309. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2010 May; 63(5):219-24. Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. PMID: 20339399.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    310. Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Dis Aquat Organ. 2010 Mar 09; 89(2):117-23. Locke JB, Vicknair MR, Ostland VE, Nizet V, Buchanan JT. PMID: 20402229.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsCTClinical Trials
    311. Accentuate the (Gram) positive. J Mol Med (Berl). 2010 Feb; 88(2):93-5. Nizet V. PMID: 20174776.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    312. Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract. Mol Microbiol. 2010 Jun; 76(6):1387-97. Kurupati P, Turner CE, Tziona I, Lawrenson RA, Alam FM, Nohadani M, Stamp GW, Zinkernagel AS, Nizet V, Edwards RJ, Sriskandan S. PMID: 20158613.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    313. Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4329-34. Stockmann C, Kerdiles Y, Nomaksteinsky M, Weidemann A, Takeda N, Doedens A, Torres-Collado AX, Iruela-Arispe L, Nizet V, Johnson RS. PMID: 20142499.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    314. Pathogen microevolution in high resolution. Sci Transl Med. 2010 Jan 27; 2(16):16ps4. Aziz RK, Nizet V. PMID: 20371473.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    315. Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One. 2010 Jan 05; 5(1):e8557. Cogen AL, Yamasaki K, Muto J, Sanchez KM, Crotty Alexander L, Tanios J, Lai Y, Kim JE, Nizet V, Gallo RL. PMID: 20052280.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    316. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol. 2010 Jan; 130(1):192-200. Cogen AL, Yamasaki K, Sanchez KM, Dorschner RA, Lai Y, MacLeod DT, Torpey JW, Otto M, Nizet V, Kim JE, Gallo RL. PMID: 19710683.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    317. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 2009 Dec 10; 114(25):5245-6. von Köckritz-Blickwede M, Chow OA, Nizet V. PMID: 20007813.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    318. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl). 2010 Apr; 88(4):371-81. Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. PMID: 19960175.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    319. The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology. 2010 Feb; 156(Pt 2):543-54. Milani CJ, Aziz RK, Locke JB, Dahesh S, Nizet V, Buchanan JT. PMID: 19762441.
      View in: PubMed   Mentions:
    320. Interdependence of hypoxic and innate immune responses. Nat Rev Immunol. 2009 Sep; 9(9):609-17. Nizet V, Johnson RS. PMID: 19704417.
      View in: PubMed   Mentions: 236     Fields:    Translation:HumansAnimalsCells
    321. Color me bad: microbial pigments as virulence factors. Trends Microbiol. 2009 Sep; 17(9):406-13. Liu GY, Nizet V. PMID: 19726196.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    322. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med. 2009 Aug 31; 206(9):1845-52. Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. PMID: 19687228.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    323. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 2009 Nov; 19(11):1204-13. Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. PMID: 19643844.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    324. Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13552-7. Lewis AL, Desa N, Hansen EE, Knirel YA, Gordon JI, Gagneux P, Nizet V, Varki A. PMID: 19666579.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    325. Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin. J Leukoc Biol. 2009 Nov; 86(5):1159-69. Jann NJ, Schmaler M, Kristian SA, Radek KA, Gallo RL, Nizet V, Peschel A, Landmann R. PMID: 19638500.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    326. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387. Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. PMID: 19633710.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    327. Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5. J Exp Med. 2009 Aug 03; 206(8):1691-9. Carlin AF, Chang YC, Areschoug T, Lindahl G, Hurtado-Ziola N, King CC, Varki A, Nizet V. PMID: 19596804.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    328. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem. 2009 Jul 09; 52(13):3869-80. Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. PMID: 19456099.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    329. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. J Innate Immun. 2009; 1(5):494-506. McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. PMID: 20375606.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    330. NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12873-8. Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, Eckmann L. PMID: 19541630.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    331. Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps. J Mol Med (Berl). 2009 Aug; 87(8):775-83. von Köckritz-Blickwede M, Nizet V. PMID: 19444424.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    332. The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier. J Infect Dis. 2009 May 15; 199(10):1479-87. van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. PMID: 19392623.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    333. Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes. PLoS One. 2009; 4(4):e5366. Cox KH, Ruiz-Bustos E, Courtney HS, Dale JB, Pence MA, Nizet V, Aziz RK, Gerling I, Price SM, Hasty DL. PMID: 19401780.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    334. Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling. Immunol Cell Biol. 2009 Aug-Sep; 87(6):496-500. Pinheiro da Silva F, Gallo RL, Nizet V. PMID: 19350049.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    335. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7107-12. Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. PMID: 19351895.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    336. Cell death during sepsis: integration of disintegration in the inflammatory response to overwhelming infection. Apoptosis. 2009 Apr; 14(4):509-21. Pinheiro da Silva F, Nizet V. PMID: 19199035.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    337. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem. 2009 May 08; 284(19):13004-12. Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. PMID: 19286651.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    338. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. J Med Chem. 2009 Feb 26; 52(4):976-88. Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. PMID: 19191557.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    339. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun. 2009; 1(3):202-14. Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. PMID: 20375578.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    340. Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response. Blood. 2009 Apr 02; 113(14):3333-6. Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A. PMID: 19196661.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    341. Bacterial phenotype variants in group B streptococcal toxic shock syndrome. Emerg Infect Dis. 2009 Feb; 15(2):223-32. Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, Norrby-Teglund A. PMID: 19193266.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    342. Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes. PLoS One. 2009; 4(1):e4166. Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Podbielbski A, Hasty DL, Dale JB. PMID: 19132104.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    343. A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence. PLoS One. 2008; 3(12):e4102. Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, Walker MJ. PMID: 19116661.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    344. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. J Biol Chem. 2009 Jan 09; 284(2):862-71. Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. PMID: 19001420.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    345. Recent advances in understanding the molecular basis of group B Streptococcus virulence. Expert Rev Mol Med. 2008 Sep 22; 10:e27. Maisey HC, Doran KS, Nizet V. PMID: 18803886.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    346. Mitochondrial missile defense. Nat Med. 2008 Sep; 14(9):910-2. Nizet V, Rothenberg ME. PMID: 18776879.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    347. The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host Microbe. 2008 Aug 14; 4(2):170-8. Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, Nizet V. PMID: 18692776.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    348. Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. PLoS One. 2008 Jul 30; 3(7):e2824. Locke JB, Aziz RK, Vicknair MR, Nizet V, Buchanan JT. PMID: 18665241.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    349. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. PLoS One. 2008 Jun 18; 3(6):e2446. Hensler ME, Miyamoto S, Nizet V. PMID: 18560574.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    350. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrob Agents Chemother. 2008 Aug; 52(8):2915-8. Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. PMID: 18541727.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    351. IKKbeta/NF-kappaB and the miscreant macrophage. J Exp Med. 2008 Jun 09; 205(6):1255-9. Timmer AM, Nizet V. PMID: 18519650.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    352. The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses. BMC Microbiol. 2008 Jun 02; 8:85. Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, Peschel A. PMID: 18518949.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    353. Innate barriers against infection and associated disorders. Drug Discov Today Dis Mech. 2008 Jun 01; 5(2):145-152. Gallo RL, Nizet V. PMID: 19492071.
      View in: PubMed   Mentions:
    354. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7803-8. Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M. PMID: 18511561.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    355. The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nat Med. 2008 Jun; 14(6):648-55. Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD. PMID: 18488037.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    356. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 2008 Jun 05; 453(7196):807-11. Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. PMID: 18432192.
      View in: PubMed   Mentions: 449     Fields:    Translation:AnimalsCells
    357. Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84. Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. PMID: 18375757.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCells
    358. Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass. Vet Microbiol. 2008 Sep 18; 131(1-2):145-53. Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, Nizet V. PMID: 18406547.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    359. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science. 2008 Mar 07; 319(5868):1405-8. McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. PMID: 18323455.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    360. Critical role of HIF-1alpha in keratinocyte defense against bacterial infection. J Invest Dermatol. 2008 Aug; 128(8):1964-8. Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, Johnson RS. PMID: 18323789.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    361. Skin microbiota: a source of disease or defence? Br J Dermatol. 2008 Mar; 158(3):442-55. Cogen AL, Nizet V, Gallo RL. PMID: 18275522.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    362. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 07; 319(5868):1391-4. Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. PMID: 18276850.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    363. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. J Bacteriol. 2008 Apr; 190(7):2275-8. Park B, Nizet V, Liu GY. PMID: 18223076.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    364. Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes. J Infect Dis. 2008 Jan 15; 197(2):214-7. Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. PMID: 18173364.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    365. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J. 2008 Jun; 22(6):1715-24. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. PMID: 18198218.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    366. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. J Biol Chem. 2008 Mar 07; 283(10):6359-66. Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, Walker MJ. PMID: 18180300.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    367. Role of the hypoxia inducible factors HIF in iron metabolism. Cell Cycle. 2008 Jan 01; 7(1):28-32. Peyssonnaux C, Nizet V, Johnson RS. PMID: 18212530.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    368. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 2007 Dec; 7(24):4488-98. Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, Walker MJ. PMID: 18072207.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    369. Hypoxia inducible factor (HIF) function in innate immunity and infection. J Mol Med (Berl). 2007 Dec; 85(12):1339-46. Zinkernagel AS, Johnson RS, Nizet V. PMID: 18030436.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    370. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorg Med Chem Lett. 2008 May 15; 18(10):3107-11. Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. PMID: 18006314.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    371. CAMP factor is not essential for systemic virulence of Group B Streptococcus. Microb Pathog. 2008 Jan; 44(1):84-8. Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. PMID: 17870297.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    372. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. J Biol Chem. 2007 Sep 21; 282(38):27562-71. Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. PMID: 17646166.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    373. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med. 2007 Aug; 13(8):981-5. Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, Henningham A, McArthur JD, Dinkla K, Aziz RK, Kansal RG, Simpson AJ, Buchanan JT, Chhatwal GS, Kotb M, Nizet V. PMID: 17632528.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimalsCells
    374. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood. 2007 Oct 15; 110(8):3039-48. Bayele HK, Peyssonnaux C, Giatromanolaki A, Arrais-Silva WW, Mohamed HS, Collins H, Giorgio S, Koukourakis M, Johnson RS, Blackwell JM, Nizet V, Srai SK. PMID: 17606764.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    375. Understanding how leading bacterial pathogens subvert innate immunity to reveal novel therapeutic targets. J Allergy Clin Immunol. 2007 Jul; 120(1):13-22. Nizet V. PMID: 17606031.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    376. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest. 2007 Jul; 117(7):1926-32. Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. PMID: 17557118.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansAnimalsCells
    377. Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis. J Immunol. 2007 Jun 15; 178(12):7516-9. Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V. PMID: 17548584.
      View in: PubMed   Mentions: 149     Fields:    Translation:AnimalsCells
    378. Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection. Dis Aquat Organ. 2007 Jun 07; 76(1):17-26. Locke JB, Colvin KM, Varki N, Vicknair MR, Nizet V, Buchanan JT. PMID: 17718161.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    379. Staphylococcus aureus: a blemish on skin immunity. Cell Host Microbe. 2007 May 17; 1(3):161-2. Zinkernagel AS, Nizet V. PMID: 18005694.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    380. How group A Streptococcus circumvents host phagocyte defenses. Future Microbiol. 2007 Feb; 2(1):75-84. Kwinn LA, Nizet V. PMID: 17661677.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    381. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. FASEB J. 2007 Apr; 21(4):1107-16. Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. PMID: 17215486.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    382. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science. 2006 Dec 15; 314(5806):1792-5. Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. PMID: 17170310.
      View in: PubMed   Mentions: 308     Fields:    Translation:HumansAnimalsCells
    383. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. J Bacteriol. 2007 Feb; 189(4):1322-9. Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. PMID: 17114267.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    384. Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. J Bacteriol. 2007 Feb; 189(4):1279-87. Locke JB, Colvin KM, Datta AK, Patel SK, Naidu NN, Neely MN, Nizet V, Buchanan JT. PMID: 17098893.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    385. Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides. Infect Immun. 2006 Nov; 74(11):6179-87. Hamilton A, Popham DL, Carl DJ, Lauth X, Nizet V, Jones AL. PMID: 17057092.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    386. Brain abscess caused by Streptococcus pyogenes in a previously healthy child. J Clin Microbiol. 2006 Dec; 44(12):4613-5. Dehority W, Uchiyama S, Khosravi A, Nizet V. PMID: 17065264.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    387. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. J Bacteriol. 2007 Feb; 189(4):1464-7. Maisey HC, Hensler M, Nizet V, Doran KS. PMID: 17041051.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    388. Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. J Bacteriol. 2007 Feb; 189(4):1231-7. Carlin AF, Lewis AL, Varki A, Nizet V. PMID: 16997964.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    389. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. EMBO J. 2006 Oct 04; 25(19):4628-37. Hidalgo-Grass C, Mishalian I, Dan-Goor M, Belotserkovsky I, Eran Y, Nizet V, Peled A, Hanski E. PMID: 16977314.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    390. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Mol Microbiol. 2006 Oct; 62(1):15-25. Timmer AM, Kristian SA, Datta V, Jeng A, Gillen CM, Walker MJ, Beall B, Nizet V. PMID: 16942605.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    391. Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorg Med Chem Lett. 2006 Oct 01; 16(19):5073-9. Hensler ME, Bernstein G, Nizet V, Nefzi A. PMID: 16890437.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    392. Trigger for group A streptococcal M1T1 invasive disease. FASEB J. 2006 Aug; 20(10):1745-7. Cole JN, McArthur JD, McKay FC, Sanderson-Smith ML, Cork AJ, Ranson M, Rohde M, Itzek A, Sun H, Ginsburg D, Kotb M, Nizet V, Chhatwal GS, Walker MJ. PMID: 16790522.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    393. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006 Feb 24; 124(4):823-35. Karin M, Lawrence T, Nizet V. PMID: 16497591.
      View in: PubMed   Mentions: 280     Fields:    Translation:HumansAnimalsCells
    394. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr Biol. 2006 Feb 21; 16(4):396-400. Buchanan JT, Simpson AJ, Aziz RK, Liu GY, Kristian SA, Kotb M, Feramisco J, Nizet V. PMID: 16488874.
      View in: PubMed   Mentions: 224     Fields:    Translation:HumansAnimalsCells
    395. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. J Biol Chem. 2006 Apr 21; 281(16):11186-92. Lewis AL, Hensler ME, Varki A, Nizet V. PMID: 16490781.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    396. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood. 2006 May 01; 107(9):3727-32. Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. PMID: 16391018.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    397. The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. FASEB J. 2006 Jan; 20(1):35-42. Dorschner RA, Lopez-Garcia B, Peschel A, Kraus D, Morikawa K, Nizet V, Gallo RL. PMID: 16394265.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    398. Antimicrobial peptide resistance mechanisms of human bacterial pathogens. Curr Issues Mol Biol. 2006 Jan; 8(1):11-26. Nizet V. PMID: 16450883.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    399. D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol. 2005 Oct; 187(19):6719-25. Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V. PMID: 16166534.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    400. Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. Infect Immun. 2005 Oct; 73(10):6935-44. Buchanan JT, Stannard JA, Lauth X, Ostland VE, Powell HC, Westerman ME, Nizet V. PMID: 16177373.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    401. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun. 2005 Oct; 73(10):6771-81. Braff MH, Zaiou M, Fierer J, Nizet V, Gallo RL. PMID: 16177355.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    402. Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest. 2005 Sep; 115(9):2499-507. Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. PMID: 16138192.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    403. A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infect Immun. 2005 Aug; 73(8):4512-21. Georgel P, Crozat K, Lauth X, Makrantonaki E, Seltmann H, Sovath S, Hoebe K, Du X, Rutschmann S, Jiang Z, Bigby T, Nizet V, Zouboulis CC, Beutler B. PMID: 16040962.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    404. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005 Jul 18; 202(2):209-15. Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. PMID: 16009720.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansAnimalsCells
    405. Cutaneous defense mechanisms by antimicrobial peptides. J Invest Dermatol. 2005 Jul; 125(1):9-13. Braff MH, Bardan A, Nizet V, Gallo RL. PMID: 15982297.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    406. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest. 2005 Jul; 115(7):1806-15. Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS. PMID: 16007254.
      View in: PubMed   Mentions: 242     Fields:    Translation:AnimalsCells
    407. Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection. Mol Microbiol. 2005 May; 56(3):681-95. Datta V, Myskowski SM, Kwinn LA, Chiem DN, Varki N, Kansal RG, Kotb M, Nizet V. PMID: 15819624.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    408. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 2005 Apr 28; 434(7037):1138-43. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. PMID: 15858576.
      View in: PubMed   Mentions: 224     Fields:    Translation:AnimalsCells
    409. Virulence role of group B Streptococcus beta-hemolysin/cytolysin in a neonatal rabbit model of early-onset pulmonary infection. J Infect Dis. 2005 Apr 15; 191(8):1287-91. Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP. PMID: 15776375.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    410. Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections. J Biol Chem. 2005 Mar 11; 280(10):9272-82. Lauth X, Babon JJ, Stannard JA, Singh S, Nizet V, Carlberg JM, Ostland VE, Pennington MW, Norton RS, Westerman ME. PMID: 15546886.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    411. Molecular pathogenesis of neonatal group B streptococcal infection: no longer in its infancy. Mol Microbiol. 2004 Oct; 54(1):23-31. Doran KS, Nizet V. PMID: 15458402.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    412. Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14491-6. Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. PMID: 15381763.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    413. Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):11123-8. Lewis AL, Nizet V, Varki A. PMID: 15263085.
      View in: PubMed   Mentions: 61     Fields:    Translation:Cells
    414. Extracellular virulence factors of group B Streptococci. Front Biosci. 2004 May 01; 9:1794-802. Liu GY, Nizet V. PMID: 14977587.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    415. Antimicrobial peptides and the skin. Expert Opin Biol Ther. 2004 Apr; 4(4):543-9. Bardan A, Nizet V, Gallo RL. PMID: 15102603.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    416. Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections. Lancet. 2004 Feb 28; 363(9410):696-703. Hidalgo-Grass C, Dan-Goor M, Maly A, Eran Y, Kwinn LA, Nizet V, Ravins M, Jaffe J, Peyser A, Moses AE, Hanski E. PMID: 15001327.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    417. Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol. 2004 Jan; 51(1):123-34. Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. PMID: 14651616.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    418. Fulminant bacterial meningitis complicating sphenoid sinusitis. Pediatr Emerg Care. 2003 Dec; 19(6):415-7. Saitoh A, Beall B, Nizet V. PMID: 14676492.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    419. Endogenous production of antimicrobial peptides in innate immunity and human disease. Curr Allergy Asthma Rep. 2003 Sep; 3(5):402-9. Gallo RL, Nizet V. PMID: 12906776.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    420. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest. 2003 Sep; 112(5):736-44. Doran KS, Liu GY, Nizet V. PMID: 12952922.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    421. Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. J Infect Dis. 2003 Aug 01; 188(3):414-23. Kristian SA, Lauth X, Nizet V, Goetz F, Neumeister B, Peschel A, Landmann R. PMID: 12870123.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    422. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol. 2003 May; 120(5):810-6. Zaiou M, Nizet V, Gallo RL. PMID: 12713586.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    423. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 2003 Mar 07; 112(5):645-57. Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. PMID: 12628185.
      View in: PubMed   Mentions: 600     Fields:    Translation:AnimalsCells
    424. Molecular genetic analysis of a group A Streptococcus operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX. J Bacteriol. 2003 Feb; 185(4):1208-17. Jeng A, Sakota V, Li Z, Datta V, Beall B, Nizet V. PMID: 12562790.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    425. Selective modulation of superantigen-induced responses by streptococcal cysteine protease. J Infect Dis. 2003 Feb 01; 187(3):398-407. Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. PMID: 12552423.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    426. Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis. 2003; 35(9):670-6. Nizet V, Gallo RL. PMID: 14620153.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    427. Streptococcal beta-hemolysins: genetics and role in disease pathogenesis. Trends Microbiol. 2002 Dec; 10(12):575-80. Nizet V. PMID: 12564994.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    428. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and beta-hemolysin/cytolysin. J Infect Dis. 2002 Nov 15; 186(10):1518-21. Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. PMID: 12404173.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    429. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. J Immunol. 2002 Oct 01; 169(7):3970-7. Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. PMID: 12244198.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    430. Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun. 2002 Oct; 70(10):5730-9. Fuller JD, Camus AC, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JC. PMID: 12228303.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    431. Surviving innate immunity. Trends Microbiol. 2002 Aug; 10(8):358-9. Nizet V, Gallo RL. PMID: 12160630.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    432. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol. 2002 Jun; 22(4):326-30. Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. PMID: 12032798.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    433. Group B streptococcal beta-hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis. 2002 Jun 15; 185(12):1745-53. Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. PMID: 12085320.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    434. Streptolysin S and necrotising infections produced by group G streptococcus. Lancet. 2002 Jan 12; 359(9301):124-9. Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. PMID: 11809255.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    435. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis. 2002 Jan 15; 185(2):196-203. Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. PMID: 11807693.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    436. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol. 2001 Dec 15; 167(12):7069-76. Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. PMID: 11739528.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    437. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15; 277(7):5030-9. Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. PMID: 11739390.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    438. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 2001 Nov 22; 414(6862):454-7. Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. PMID: 11719807.
      View in: PubMed   Mentions: 339     Fields:    Translation:AnimalsCells
    439. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol. 2001 Jul; 117(1):91-7. Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. PMID: 11442754.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    440. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature. J Infect. 2001 May; 42(4):272-7. Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. PMID: 11545571.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    441. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun. 2001 Apr; 69(4):1994-2000. Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC. PMID: 11254550.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    442. Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus. Mol Microbiol. 2001 Jan; 39(2):236-47. Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V. PMID: 11136446.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    443. Severity of group B streptococcal arthritis is correlated with beta-hemolysin expression. J Infect Dis. 2000 Sep; 182(3):824-32. Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. PMID: 10950777.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    444. Genetic locus for streptolysin S production by group A streptococcus. Infect Immun. 2000 Jul; 68(7):4245-54. Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. PMID: 10858242.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    445. Group B streptococcal beta-hemolysin induces nitric oxide production in murine macrophages. J Infect Dis. 2000 Jul; 182(1):150-7. Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. PMID: 10882592.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    446. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun. 2000 Feb; 68(2):637-43. Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. PMID: 10639427.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    447. Group B streptococcal beta-hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res. 1999 May; 45(5 Pt 1):626-34. Gibson RL, Nizet V, Rubens CE. PMID: 10231855.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    448. Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun. 1997 Dec; 65(12):5074-81. Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. PMID: 9393798.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    449. The role of group B streptococci beta-hemolysin expression in newborn lung injury. Adv Exp Med Biol. 1997; 418:627-30. Nizet V, Gibson RL, Rubens CE. PMID: 9331730.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    450. Epithelial cell invasion by group B streptococci is important to virulence. Adv Exp Med Biol. 1997; 418:631-4. La Penta D, Framson P, Nizet V, Rubens C. PMID: 9331731.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    451. Group B streptococcal beta-hemolysin expression is associated with injury of lung epithelial cells. Infect Immun. 1996 Sep; 64(9):3818-26. Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. PMID: 8751934.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    452. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella. J Pediatr Orthop. 1996 Jul-Aug; 16(4):522-8. Mills WJ, Mosca VS, Nizet V. PMID: 8784712.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    453. Streptococcal skin infections. N Engl J Med. 1996 May 30; 334(22):1478. Brogan TV, Nizet V, Waldhausen JH. PMID: 8618597.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    454. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis. 1996 Jan; 173(1):180-6. Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. PMID: 8537657.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    455. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. Pediatr Infect Dis J. 1995 Jul; 14(7):588-94. Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. PMID: 7567287.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    456. A newborn girl with watery diarrhea, weight loss, and severe metabolic acidosis. Curr Opin Pediatr. 1994 Apr; 6(2):163-7. Nizet V, Priebe CJ. PMID: 8032396.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    457. Fever in children. Pediatr Rev. 1994 Apr; 15(4):127-35. Nizet V, Vinci RJ, Lovejoy FH. PMID: 8015996.
      View in: PubMed   Mentions: 1