Victor Nizet

InstitutionUniversity of California San Diego
DepartmentSchool of Pharmacy and Pharmaceutical Science
Address9500 Gilman Drive #0760
La Jolla CA 92093
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    Collapse Biography 
    Collapse Awards and Honors
    2017UCSD Chancellor's Associates Award for Excellence in Research in Science & Engineering
    2013UCSD Chancellor's Award for Excellence in Postdoctoral Scholar Mentoring
    2013Rady Children’s Hospital Award for Excellence in Research
    2012Elected to Fellowship in the American Academy of Microbiology
    2010Elected to Membership in the Association of American Physicians
    2008E. Mead Johnson Award for Research in Pediatrics, Society for Pediatric Research
    2008Stephen Silberstein Senior Fellow of the American Asthma Foundation
    2006Elected to Membership in the American Society for Clinical Investigation
    2006Elected to the American Pediatric Society
    2004Career Investigator Award, American Lung Association
    2004Established Investigator Award, American Heart Association
    2002Named the 39th Mallinckrodt Scholar by the Edward Mallinckrodt, Jr. Foundation
    2002Pediatric Infectious Diseases Society Young Investigator Award
    2002Elected to the Society for Pediatric Research
    2001UCSD Department of Pediatrics Commitment to Resident Education Award
    2000UCSD Department of Pediatrics Outstanding Faculty Teacher of the Year
    1993Sidney Farber Outstanding Houseofficer Award, Children’s Hospital, Boston
    1984Class of 1922 Award, Reed College, “Most Outstanding Senior Thesis”
    1984Phi Beta Kappa, Reed College

    Collapse Overview 
    Collapse Overview
    Victor Nizet is a Professor of Pediatrics and Pharmacy at the University of California, San Diego and Chief of the Division of Pediatric Pharmacology & Drug Discovery at University of California San Diego (UCSD) School of Medicine and Skaggs School of Pharmacy & Pharmaceutical Sciences. Dr. Nizet received his medical training at Stanford University School of Medicine, completed a Residency and Chief Residency in Pediatrics at Harvard University's Children's Hospital in Boston, Massachusetts, and a Fellowship in Pediatric Infectious Diseases at the University of Washington's Children's Hospital in Seattle. Dr. Nizet joined the UCSD faculty in 1997 and leads a large basic and translational research laboratory focused on discovering virulence factors of Gram-positive bacterial pathogens, elucidating mechanisms of host innate immunity, and novel approaches to infectious disease therapy.

    Collapse Interests

    Collapse Research 
    Collapse Research Activities and Funding
    Broad recognition of group A Streptococcus M proteins
    NIH/NIAID R21AI140436May 18, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH/NICHD U54HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Glycoprotein Remodeling in the Vasculopathy and Coagulopathy of Sepsis
    NIH/NHLBI R01HL125352Sep 15, 2014 - May 31, 2019
    Role: Principal Investigator
    Analyzing a novel mechanism of action of bacterial cAMP producing toxins
    NIH/NIAID R01AI110713Feb 1, 2014 - Jan 31, 2019
    Role: Principal Investigator
    Glycan Modulation of Inflammatory Responses
    NIH P01HL107150Jul 1, 2011 - May 31, 2018
    Role: Co-Investigator
    Mechanisms of the M protein in group A Streptococcus virulence
    NIH/NIAID R01AI096837Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections
    NIH/NIAID R01AI093451Apr 5, 2011 - Mar 31, 2016
    Role: Principal Investigator
    Boosting Innate Immunity Through HIF to Treat Drug-Resistant Bacterial Infections
    NIH/NIAID R56AI090863Aug 2, 2010 - Jul 31, 2011
    Role: Principal Investigator
    GAS Switch from Colonizing Bacterium to Invasive Pathogen
    NIH/NIAID R01AI077780Sep 1, 2008 - Jan 31, 2020
    Role: Principal Investigator
    Sialic Acid O-Acetylation in GBS Pathogenesis &Immunity
    NIH/NICHD R01HD051796Apr 7, 2006 - Feb 28, 2012
    Role: Principal Investigator
    Molecular Analyses and Interventions for Biodefense and Emerging Pathogens
    NIH U54AI057153Sep 4, 2003 - Feb 28, 2014
    Role: Co-Investigator
    Cathelicidin in Skin Immunity
    NIH/NIAID R01AI052453Sep 15, 2002 - Mar 31, 2018
    Role: Principal Investigator
    SLS: Molecular Basis and Role in Invasive GAS Disease
    NIH/NIAID R01AI048694Apr 1, 2002 - Mar 31, 2007
    Role: Principal Investigator
    NIH/NICHD R03HD037224Feb 1, 1999 - Aug 31, 2001
    Role: Principal Investigator
    NIH/NIAID K08AI001451Apr 1, 1997 - Mar 31, 2001
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Alisson-Silva F, Liu JZ, Diaz SL, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A. Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera. PLoS Pathog. 2018 Jun 18; 14(6):e1007133. PMID: 29912959.
      View in: PubMed
    2. Askarian F, Wagner T, Johannessen M, Nizet V. Staphylococcus aureus modulation of innate immune responses through Toll-like (TLRs), (NOD)-like (NLRs) and C-type lectin (CLRs) receptors. FEMS Microbiol Rev. 2018 Jun 08. PMID: 29893825.
      View in: PubMed
    3. Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. J Infect Dis. 2018 Jun 04. PMID: 29868829.
      View in: PubMed
    4. Kumaraswamy M, Collignon S, Do C, Kim J, Nizet V, Friend J. Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device. Appl Microbiol Biotechnol. 2018 May 26. PMID: 29804135.
      View in: PubMed
    5. Soderholm AT, Barnett TC, Korn O, Rivera-Hernandez T, Seymour LM, Schulz BL, Nizet V, Wells CA, Sweet MJ, Walker MJ. Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP. Front Cell Infect Microbiol. 2018; 8:160. PMID: 29868516.
      View in: PubMed
    6. Gupta N, Nizet V. Stabilization of Hypoxia-Inducible Factor-1 Alpha Augments the Therapeutic Capacity of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Pneumonia. Front Med (Lausanne). 2018; 5:131. PMID: 29780805.
      View in: PubMed
    7. Jati S, Kundu S, Chakraborty A, Mahata SK, Nizet V, Sen M. Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit. Front Immunol. 2018; 9:679. PMID: 29686674.
      View in: PubMed
    8. Monogue ML, Sakoulas G, Nizet V, Nicolau DP. Humanized Exposures of a ß-Lactam-ß-Lactamase Inhibitor, Tazobactam, versus Non-ß-Lactam-ß-Lactamase Inhibitor, Avibactam, with or without Colistin, against Acinetobacter baumannii in Murine Thigh and Lung Infection Models. Pharmacology. 2018; 101(5-6):255-261. PMID: 29533955.
      View in: PubMed
    9. Gupta N, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin JH, Nizet V, Corriden R. SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity. J Antimicrob Chemother. 2018 Mar 05. PMID: 29514266.
      View in: PubMed
    10. Patras KA, Nizet V. Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches. Front Pediatr. 2018; 6:27. PMID: 29520354.
      View in: PubMed
    11. Haripriyan J, Omanakuttan A, Menon ND, Vanuopadath M, Nair SS, Corriden R, Nair BG, Nizet V, Kumar GB. Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa. Sci Rep. 2018 Feb 21; 8(1):3437. PMID: 29467483.
      View in: PubMed
    12. Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Front Microbiol. 2018; 9:262. PMID: 29515544.
      View in: PubMed
    13. Chen Y, Chen M, Zhang Y, Lee JH, Escajadillo T, Gong H, Fang RH, Gao W, Nizet V, Zhang L. Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges. Adv Healthc Mater. 2018 Feb 13. PMID: 29436150.
      View in: PubMed
    14. Lawrence SM, Corriden R, Nizet V. The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis. Microbiol Mol Biol Rev. 2018 Jun; 82(1). PMID: 29436479.
      View in: PubMed
    15. Choe D, Szubin R, Dahesh S, Cho S, Nizet V, Palsson B, Cho BK. Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance. Sci Rep. 2018 Feb 02; 8(1):2215. PMID: 29396540.
      View in: PubMed
    16. Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia. Stem Cells. 2018 Feb 02. PMID: 29396891.
      View in: PubMed
    17. Henningham A, Davies MR, Uchiyama S, van Sorge NM, Lund S, Chen KT, Walker MJ, Cole JN, Nizet V. Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus. MBio. 2018 Jan 30; 9(1). PMID: 29382733.
      View in: PubMed
    18. Liu JZ, Ali SR, Bier E, Nizet V. Innate Immune Interactions between Bacillus anthracis and Host Neutrophils. Front Cell Infect Microbiol. 2018; 8:2. PMID: 29404280.
      View in: PubMed
    19. Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V. Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies. Int J Antimicrob Agents. 2018 Mar; 51(3):468-478. PMID: 29337066.
      View in: PubMed
    20. Andreoni F, Ugolini F, Keller N, Neff A, Nizet V, Hollands A, Marques Maggio E, Zinkernagel AS, Schuepbach RA. Immunoglobulin Attenuates Streptokinase-Mediated Virulence in Streptococcus dysgalactiae Subspecies equisimilis Necrotizing Fasciitis. J Infect Dis. 2018 Jan 04; 217(2):270-279. PMID: 29099935.
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    21. Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, de A Zanotto PM, Beltrão-Braga PCB, Nizet V, Muotri AR. Modeling neuro-immune interactions during Zika virus infection. Hum Mol Genet. 2018 Jan 01; 27(1):41-52. PMID: 29048558.
      View in: PubMed
    22. Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD. Recurrent infection progressively disables host protection against intestinal inflammation. Science. 2017 12 22; 358(6370). PMID: 29269445.
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    23. Catteau L, Reichmann NT, Olson J, Pinho MG, Nizet V, Van Bambeke F, Quetin-Leclercq J. Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and ß-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms. Molecules. 2017 Dec 16; 22(12). PMID: 29258194.
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    24. Britt NS, Tirmizi S, Ritchie DJ, Topal JE, McManus D, Nizet V, Casabar E, Sakoulas G. Telavancin for refractory MRSA bacteraemia in intermittent haemodialysis recipients. J Antimicrob Chemother. 2017 Dec 13. PMID: 29244141.
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    25. Valderrama JA, Nizet V. Group A Streptococcus encounters with host macrophages. Future Microbiol. 2018 Jan; 13:119-134. PMID: 29226710.
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    26. Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. J Nat Prod. 2018 Mar 23; 81(3):506-514. PMID: 29215273.
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    27. Sakoulas G, Kumaraswamy M, Kousha A, Nizet V. Interaction of Antibiotics with Innate Host Defense Factors against Salmonella enterica Serotype Newport. mSphere. 2017 Nov-Dec; 2(6). PMID: 29242830.
      View in: PubMed
    28. Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. J Antibiot (Tokyo). 2018 Feb; 71(2):333-338. PMID: 29184121.
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    29. Zhang Y, Gao W, Chen Y, Escajadillo T, Ungerleider J, Fang RH, Christman K, Nizet V, Zhang L. Self-Assembled Colloidal Gel Using Cell Membrane-Coated Nanosponges as Building Blocks. ACS Nano. 2017 Dec 26; 11(12):11923-11930. PMID: 29116753.
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    30. Thamphiwatana S, Angsantikul P, Escajadillo T, Zhang Q, Olson J, Luk BT, Zhang S, Fang RH, Gao W, Nizet V, Zhang L. Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management. Proc Natl Acad Sci U S A. 2017 Oct 24; 114(43):11488-11493. PMID: 29073076.
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    31. Guichard A, Jain P, Moayeri M, Schwartz R, Chin S, Zhu L, Cruz-Moreno B, Liu JZ, Aguilar B, Hollands A, Leppla SH, Nizet V, Bier E. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. PLoS Pathog. 2017 Sep; 13(9):e1006603. PMID: 28945820.
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    32. Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, Nizet V, Lin L, McCauley MD, Strathdee SA, Benson CA, Pope RK, Leroux BM, Picel AC, Mateczun AJ, Cilwa KE, Regeimbal JM, Estrella LA, Wolfe DM, Henry MS, Quinones J, Salka S, Bishop-Lilly KA, Young R, Hamilton T. Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection. Antimicrob Agents Chemother. 2017 Oct; 61(10). PMID: 28807909.
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    33. Sun J, Lei L, Tsai CM, Wang Y, Shi Y, Ouyang M, Lu S, Seong J, Kim TJ, Wang P, Huang M, Xu X, Nizet V, Chien S, Wang Y. Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions. Nat Commun. 2017 09 07; 8(1):477. PMID: 28883531.
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    34. Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V. The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance. J Mol Med (Berl). 2017 Oct; 95(10):1127-1136. PMID: 28844103.
      View in: PubMed
    35. Patras KA, Coady A, Olson J, Ali SR, RamachandraRao SP, Kumar S, Varki A, Nizet V. Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract. Immunol Cell Biol. 2017 Nov; 95(10):960-965. PMID: 28829050.
      View in: PubMed
    36. Valderrama JA, Riestra AM, Gao NJ, LaRock CN, Gupta N, Ali SR, Hoffman HM, Ghosh P, Nizet V. Group A streptococcal M protein activates the NLRP3 inflammasome. Nat Microbiol. 2017 Oct; 2(10):1425-1434. PMID: 28784982.
      View in: PubMed
    37. Escajadillo T, Olson J, Luk BT, Zhang L, Nizet V. A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus. Front Pharmacol. 2017; 8:477. PMID: 28769806.
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    38. Nizet V. The Accidental Orthodoxy of Drs. Mueller and Hinton. EBioMedicine. 2017 Aug; 22:26-27. PMID: 28689739.
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    39. Severino P, Ariga SK, Barbeiro HV, de Lima TM, de Paula Silva E, Barbeiro DF, Machado MCC, Nizet V, Pinheiro da Silva F. Cathelicidin-deficient mice exhibit increased survival and upregulation of key inflammatory response genes following cecal ligation and puncture. J Mol Med (Berl). 2017 Sep; 95(9):995-1003. PMID: 28623379.
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    40. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2017 Jun 12; 2:17107. PMID: 28604710.
      View in: PubMed
    41. Rose WE, Shukla SK, Berti AD, Hayney MS, Henriquez KM, Ranzoni A, Cooper MA, Proctor RA, Nizet V, Sakoulas G. Increased Endovascular Staphylococcus aureus Inoculum Is the Link Between Elevated Serum Interleukin 10 Concentrations and Mortality in Patients With Bacteremia. Clin Infect Dis. 2017 May 15; 64(10):1406-1412. PMID: 28205673.
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    42. Lizcano A, Secundino I, Döhrmann S, Corriden R, Rohena C, Diaz S, Ghosh P, Deng L, Nizet V, Varki A. Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation. Blood. 2017 06 08; 129(23):3100-3110. PMID: 28416510.
      View in: PubMed
    43. Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. Human milk oligosaccharides inhibit growth of group B Streptococcus. J Biol Chem. 2017 07 07; 292(27):11243-11249. PMID: 28416607.
      View in: PubMed
    44. Storisteanu DM, Pocock JM, Cowburn AS, Juss JK, Nadesalingam A, Nizet V, Chilvers ER. Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens. Am J Respir Cell Mol Biol. 2017 04; 56(4):423-431. PMID: 27854516.
      View in: PubMed
    45. Munguia J, Nizet V. Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs. Trends Pharmacol Sci. 2017 05; 38(5):473-488. PMID: 28283200.
      View in: PubMed
    46. Lawrence SM, Corriden R, Nizet V. Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil. Front Pediatr. 2017; 5:23. PMID: 28293548.
      View in: PubMed
    47. Caffrey AR, Timbrook TT, Noh E, Sakoulas G, Opal SM, Nizet V, LaPlante KL. Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2017 Mar; 61(3). PMID: 28069650.
      View in: PubMed
    48. Döhrmann S, LaRock CN, Anderson EL, Cole JN, Ryali B, Stewart C, Nonejuie P, Pogliano J, Corriden R, Ghosh P, Nizet V. Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones. Sci Rep. 2017 Feb 21; 7:43039. PMID: 28220899.
      View in: PubMed
    49. Okerblom JJ, Schwarz F, Olson J, Fletes W, Ali SR, Martin PT, Glass CK, Nizet V, Varki A. Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. J Immunol. 2017 03 15; 198(6):2366-2373. PMID: 28148732.
      View in: PubMed
    50. De Oliveira DM, Hartley-Tassell L, Everest-Dass A, Day CJ, Dabbs RA, Ve T, Kobe B, Nizet V, Packer NH, Walker MJ, Jennings MP, Sanderson-Smith ML. Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization. MBio. 2017 01 24; 8(1). PMID: 28119471.
      View in: PubMed
    51. Sakoulas G, Rose W, Berti A, Olson J, Munguia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V. Classical ß-Lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin against Acinetobacter baumannii. Antimicrob Agents Chemother. 2017 Feb; 61(2). PMID: 27872080.
      View in: PubMed
    52. Schwarz F, Landig CS, Siddiqui S, Secundino I, Olson J, Varki N, Nizet V, Varki A. Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. EMBO J. 2017 03 15; 36(6):751-760. PMID: 28100677.
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    53. van Wijk XM, Döhrmann S, Hallström BM, Li S, Voldborg BG, Meng BX, McKee KK, van Kuppevelt TH, Yurchenco PD, Palsson BO, Lewis NE, Nizet V, Esko JD. Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin a2 as a Host Factor for Bacterial Invasion. MBio. 2017 01 10; 8(1). PMID: 28074024.
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    54. Askarian F, Uchiyama S, Valderrama JA, Ajayi C, Sollid JU, van Sorge NM, Nizet V, van Strijp JA, Johannessen M. Serine-Aspartate Repeat Protein D Increases Staphylococcus aureus Virulence and Survival in Blood. Infect Immun. 2017 Jan; 85(1). PMID: 27795358.
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    55. Sorg RA, Lin L, van Doorn GS, Sorg M, Olson J, Nizet V, Veening JW. Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation. PLoS Biol. 2016 Dec; 14(12):e2000631. PMID: 28027306.
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    56. Flores R, Döhrmann S, Schaal C, Hakkim A, Nizet V, Corriden R. The Selective Estrogen Receptor Modulator Raloxifene Inhibits Neutrophil Extracellular Trap Formation. Front Immunol. 2016; 7:566. PMID: 28003814.
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    57. Coady A, Nizet V. SAMP-ending down sepsis. Ann Transl Med. 2016 Dec; 4(24):509. PMID: 28149871.
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    58. Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V. Cefazolin and Ertapenem, a Synergistic Combination Used To Clear Persistent Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2016 11; 60(11):6609-6618. PMID: 27572414.
      View in: PubMed
    59. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol. 2016 Sep 05; 1(11):16155. PMID: 27595425.
      View in: PubMed
    60. Hentrich K, Löfling J, Pathak A, Nizet V, Varki A, Henriques-Normark B. Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. Cell Host Microbe. 2016 Sep 14; 20(3):307-317. PMID: 27593514; PMCID: PMC5025396 [Available on 09/14/17].
    61. LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. IL-1ß is an innate immune sensor of microbial proteolysis. Sci Immunol. 2016 Aug; 1(2). PMID: 28331908.
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    62. LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AAB, Cooper MA, Hoffman HM, Nizet V. IL-1ß is an innate immune sensor of microbial proteolysis. Sci Immunol. 2016 Aug 19; 1(2):eaah3539. PMID: 28783696.
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    63. Stewart CM, Buffalo CZ, Valderrama JA, Henningham A, Cole JN, Nizet V, Ghosh P. Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):9515-20. PMID: 27512043; PMCID: PMC5003295 [Available on 02/23/17].
    64. Döhrmann S, Cole JN, Nizet V. Conquering Neutrophils. PLoS Pathog. 2016 07; 12(7):e1005682. PMID: 27467389; PMCID: PMC4965185.
    65. Makoni M, Eckert J, Anne Pereira H, Nizet V, Lawrence SM. Alterations in neonatal neutrophil function attributable to increased immature forms. Early Hum Dev. 2016 12; 103:1-7. PMID: 27428466.
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    66. Yamaguchi M, Hirose Y, Nakata M, Uchiyama S, Yamaguchi Y, Goto K, Sumitomo T, Lewis AL, Kawabata S, Nizet V. Evolutionary inactivation of a sialidase in group B Streptococcus. Sci Rep. 2016 06 29; 6:28852. PMID: 27352769.
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    67. Lin L, Kim J, Chen H, Kowalski R, Nizet V. Component Analysis of Multipurpose Contact Lens Solutions To Enhance Activity against Pseudomonas aeruginosa and Staphylococcus aureus. Antimicrob Agents Chemother. 2016 07; 60(7):4259-63. PMID: 27139484; PMCID: PMC4914654 [Available on 01/01/17].
    68. Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, Walker MJ. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. MBio. 2016 06 14; 7(3). PMID: 27302756; PMCID: PMC4916377.
    69. Bosi E, Monk JM, Aziz RK, Fondi M, Nizet V, Palsson BØ. Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3801-9. PMID: 27286824; PMCID: PMC4932939.
    70. Carey AJ, Weinberg JB, Dawid SR, Venturini C, Lam AK, Nizet V, Caparon MG, Walker MJ, Watson ME, Ulett GC. Interleukin-17A Contributes to the Control of Streptococcus pyogenes Colonization and Inflammation of the Female Genital Tract. Sci Rep. 2016 05 31; 6:26836. PMID: 27241677.
      View in: PubMed
    71. Le J, Dam Q, Schweizer M, Thienphrapa W, Nizet V, Sakoulas G. Effects of vancomycin versus nafcillin in enhancing killing of methicillin-susceptible Staphylococcus aureus causing bacteremia by human cathelicidin LL-37. Eur J Clin Microbiol Infect Dis. 2016 Sep; 35(9):1441-7. PMID: 27234592; PMCID: PMC4983239 [Available on 09/01/17].
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    229. Yang H, Sikavi C, Tran K, McGillivray SM, Nizet V, Yung M, Chang A, Miller JH. Papillation in Bacillus anthracis colonies: a tool for finding new mutators. Mol Microbiol. 2011 Mar; 79(5):1276-93. PMID: 21205011.
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    230. Reiss A, Braun JS, Jäger K, Freyer D, Laube G, Bührer C, Felderhoff-Müser U, Stadelmann C, Nizet V, Weber JR. Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis. 2011 Feb 01; 203(3):393-400. PMID: 21186256; PMCID: PMC3071107.
    231. Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1ß-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKß. Nat Immunol. 2011 Feb; 12(2):144-50. PMID: 21170027; PMCID: PMC3677078.
    232. Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010 Nov 18; 8(5):445-54. PMID: 21075355; PMCID: PMC3008410.
    233. Guichard A, McGillivray SM, Cruz-Moreno B, van Sorge NM, Nizet V, Bier E. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. Nature. 2010 Oct 14; 467(7317):854-8. PMID: 20944747.
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    234. Nizet V. Bacteria and phagocytes: mortal enemies. J Innate Immun. 2010; 2(6):505-7. PMID: 20829606.
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    236. Maamary PG, Sanderson-Smith ML, Aziz RK, Hollands A, Cole JN, McKay FC, McArthur JD, Kirk JK, Cork AJ, Keefe RJ, Kansal RG, Sun H, Taylor WL, Chhatwal GS, Ginsburg D, Nizet V, Kotb M, Walker MJ. Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. J Innate Immun. 2010; 2(6):596-606. PMID: 20814186; PMCID: PMC3219504.
    237. Pence MA, Rooijakkers SH, Cogen AL, Cole JN, Hollands A, Gallo RL, Nizet V. Streptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A Streptococcus. J Innate Immun. 2010; 2(6):587-95. PMID: 20814187; PMCID: PMC3219503.
    238. Cole JN, Pence MA, von Köckritz-Blickwede M, Hollands A, Gallo RL, Walker MJ, Nizet V. M protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus. MBio. 2010 Aug 31; 1(4). PMID: 20827373; PMCID: PMC2934611.
    239. Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16286-90. PMID: 20805502; PMCID: PMC2941286.
    240. Derbal S, Hensler M, Fang W, Nizet V, Ghedira K, Nefzi A. On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity. Bioorg Med Chem Lett. 2010 Oct 01; 20(19):5701-4. PMID: 20800485; PMCID: PMC2963184.
    241. Zhao HW, Zhou D, Nizet V, Haddad GG. Experimental selection for Drosophila survival in extremely high O2 environments. PLoS One. 2010 Jul 23; 5(7):e11701. PMID: 20668515; PMCID: PMC2909141.
    242. Taylor RE, Gregg CJ, Padler-Karavani V, Ghaderi D, Yu H, Huang S, Sorensen RU, Chen X, Inostroza J, Nizet V, Varki A. Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid. J Exp Med. 2010 Aug 02; 207(8):1637-46. PMID: 20624889.
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    243. Rooijakkers SH, Rasmussen SL, McGillivray SM, Bartnikas TB, Mason AB, Friedlander AM, Nizet V. Human transferrin confers serum resistance against Bacillus anthracis. J Biol Chem. 2010 Sep 03; 285(36):27609-13. PMID: 20615872; PMCID: PMC2934628.
    244. Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, Walker MJ, Nizet V. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. J Infect Dis. 2010 Jul 01; 202(1):11-9. PMID: 20507231; PMCID: PMC2880657.
    245. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. PMID: 20581111; PMCID: PMC2934687.
    246. Kaur SJ, Nerlich A, Bergmann S, Rohde M, Fulde M, Zähner D, Hanski E, Zinkernagel A, Nizet V, Chhatwal GS, Talay SR. The CXC chemokine-degrading protease SpyCep of Streptococcus pyogenes promotes its uptake into endothelial cells. J Biol Chem. 2010 Sep 03; 285(36):27798-805. PMID: 20562101; PMCID: PMC2934647.
    247. Weiman S, Uchiyama S, Lin FY, Chaffin D, Varki A, Nizet V, Lewis AL. O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. Biochem J. 2010 May 13; 428(2):163-8. PMID: 20334627.
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    248. Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2010 May; 63(5):219-24. PMID: 20339399; PMCID: PMC2889693.
    249. Locke JB, Vicknair MR, Ostland VE, Nizet V, Buchanan JT. Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Dis Aquat Organ. 2010 Mar 09; 89(2):117-23. PMID: 20402229.
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    250. Nizet V. Accentuate the (Gram) positive. J Mol Med (Berl). 2010 Feb; 88(2):93-5. PMID: 20174776.
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    251. Kurupati P, Turner CE, Tziona I, Lawrenson RA, Alam FM, Nohadani M, Stamp GW, Zinkernagel AS, Nizet V, Edwards RJ, Sriskandan S. Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract. Mol Microbiol. 2010 Jun; 76(6):1387-97. PMID: 20158613; PMCID: PMC2904501.
    252. Stockmann C, Kerdiles Y, Nomaksteinsky M, Weidemann A, Takeda N, Doedens A, Torres-Collado AX, Iruela-Arispe L, Nizet V, Johnson RS. Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4329-34. PMID: 20142499; PMCID: PMC2840078.
    253. Aziz RK, Nizet V. Pathogen microevolution in high resolution. Sci Transl Med. 2010 Jan 27; 2(16):16ps4. PMID: 20371473.
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    254. Cogen AL, Yamasaki K, Muto J, Sanchez KM, Crotty Alexander L, Tanios J, Lai Y, Kim JE, Nizet V, Gallo RL. Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One. 2010 Jan 05; 5(1):e8557. PMID: 20052280; PMCID: PMC2796718.
    255. Cogen AL, Yamasaki K, Sanchez KM, Dorschner RA, Lai Y, MacLeod DT, Torpey JW, Otto M, Nizet V, Kim JE, Gallo RL. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol. 2010 Jan; 130(1):192-200. PMID: 19710683; PMCID: PMC2796468.
    256. von Köckritz-Blickwede M, Chow OA, Nizet V. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 2009 Dec 10; 114(25):5245-6. PMID: 20007813; PMCID: PMC2792215.
    257. Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl). 2010 Apr; 88(4):371-81. PMID: 19960175; PMCID: PMC2843839.
    258. Milani CJ, Aziz RK, Locke JB, Dahesh S, Nizet V, Buchanan JT. The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology. 2010 Feb; 156(Pt 2):543-54. PMID: 19762441; PMCID: PMC2890087.
    259. Nizet V, Johnson RS. Interdependence of hypoxic and innate immune responses. Nat Rev Immunol. 2009 Sep; 9(9):609-17. PMID: 19704417; PMCID: PMC4343208.
    260. Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors. Trends Microbiol. 2009 Sep; 17(9):406-13. PMID: 19726196; PMCID: PMC2743764.
    261. Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med. 2009 Aug 31; 206(9):1845-52. PMID: 19687228; PMCID: PMC2737157.
    262. Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 2009 Nov; 19(11):1204-13. PMID: 19643844.
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    263. Lewis AL, Desa N, Hansen EE, Knirel YA, Gordon JI, Gagneux P, Nizet V, Varki A. Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13552-7. PMID: 19666579; PMCID: PMC2726416.
    264. Jann NJ, Schmaler M, Kristian SA, Radek KA, Gallo RL, Nizet V, Peschel A, Landmann R. Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin. J Leukoc Biol. 2009 Nov; 86(5):1159-69. PMID: 19638500; PMCID: PMC3192022.
    265. Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387. PMID: 19633710.
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    266. Carlin AF, Chang YC, Areschoug T, Lindahl G, Hurtado-Ziola N, King CC, Varki A, Nizet V. Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5. J Exp Med. 2009 Aug 03; 206(8):1691-9. PMID: 19596804; PMCID: PMC2722167.
    267. Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem. 2009 Jul 09; 52(13):3869-80. PMID: 19456099; PMCID: PMC2753857.
    268. McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. J Innate Immun. 2009; 1(5):494-506. PMID: 20375606; PMCID: PMC2920483.
    269. Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, Eckmann L. NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12873-8. PMID: 19541630; PMCID: PMC2722361.
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    271. van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier. J Infect Dis. 2009 May 15; 199(10):1479-87. PMID: 19392623; PMCID: PMC2674616.
    272. Cox KH, Ruiz-Bustos E, Courtney HS, Dale JB, Pence MA, Nizet V, Aziz RK, Gerling I, Price SM, Hasty DL. Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes. PLoS One. 2009; 4(4):e5366. PMID: 19401780; PMCID: PMC2671602.
    273. Pinheiro da Silva F, Gallo RL, Nizet V. Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling. Immunol Cell Biol. 2009 Aug-Sep; 87(6):496-500. PMID: 19350049; PMCID: PMC2763337.
    274. Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7107-12. PMID: 19351895; PMCID: PMC2678456.
    275. Pinheiro da Silva F, Nizet V. Cell death during sepsis: integration of disintegration in the inflammatory response to overwhelming infection. Apoptosis. 2009 Apr; 14(4):509-21. PMID: 19199035.
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    277. Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. J Med Chem. 2009 Feb 26; 52(4):976-88. PMID: 19191557; PMCID: PMC2765255.
    278. Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun. 2009; 1(3):202-14. PMID: 20375578; PMCID: PMC3241932.
    279. Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A. Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response. Blood. 2009 Apr 02; 113(14):3333-6. PMID: 19196661; PMCID: PMC2665898.
    280. Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, Norrby-Teglund A. Bacterial phenotype variants in group B streptococcal toxic shock syndrome. Emerg Infect Dis. 2009 Feb; 15(2):223-32. PMID: 19193266; PMCID: PMC2657631.
    281. Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Podbielbski A, Hasty DL, Dale JB. Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes. PLoS One. 2009; 4(1):e4166. PMID: 19132104.
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    282. Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, Walker MJ. A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence. PLoS One. 2008; 3(12):e4102. PMID: 19116661; PMCID: PMC2605554.
    283. Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. J Biol Chem. 2009 Jan 09; 284(2):862-71. PMID: 19001420; PMCID: PMC2613605.
    284. Maisey HC, Doran KS, Nizet V. Recent advances in understanding the molecular basis of group B Streptococcus virulence. Expert Rev Mol Med. 2008 Sep 22; 10:e27. PMID: 18803886; PMCID: PMC2676346.
    285. Nizet V, Rothenberg ME. Mitochondrial missile defense. Nat Med. 2008 Sep; 14(9):910-2. PMID: 18776879.
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    286. Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, Nizet V. The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host Microbe. 2008 Aug 14; 4(2):170-8. PMID: 18692776; PMCID: PMC2631432.
    287. Locke JB, Aziz RK, Vicknair MR, Nizet V, Buchanan JT. Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. PLoS One. 2008 Jul 30; 3(7):e2824. PMID: 18665241; PMCID: PMC2483786.
    288. Hensler ME, Miyamoto S, Nizet V. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. PLoS One. 2008 Jun 18; 3(6):e2446. PMID: 18560574; PMCID: PMC2409074.
    289. Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrob Agents Chemother. 2008 Aug; 52(8):2915-8. PMID: 18541727; PMCID: PMC2493126.
    290. Timmer AM, Nizet V. IKKbeta/NF-kappaB and the miscreant macrophage. J Exp Med. 2008 Jun 09; 205(6):1255-9. PMID: 18519650; PMCID: PMC2413023.
    291. Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, Peschel A. The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses. BMC Microbiol. 2008 Jun 02; 8:85. PMID: 18518949; PMCID: PMC2430206.
    292. Gallo RL, Nizet V. Innate barriers against infection and associated disorders. Drug Discov Today Dis Mech. 2008 Jun 01; 5(2):145-152. PMID: 19492071.
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    293. Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7803-8. PMID: 18511561; PMCID: PMC2409384.
    294. Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD. The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nat Med. 2008 Jun; 14(6):648-55. PMID: 18488037; PMCID: PMC2853759.
    295. Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 2008 Jun 05; 453(7196):807-11. PMID: 18432192; PMCID: PMC2669289.
    296. Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84. PMID: 18375757; PMCID: PMC2311365.
    297. Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, Nizet V. Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass. Vet Microbiol. 2008 Sep 18; 131(1-2):145-53. PMID: 18406547.
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    298. McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science. 2008 Mar 07; 319(5868):1405-8. PMID: 18323455; PMCID: PMC2288698.
    299. Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, Johnson RS. Critical role of HIF-1alpha in keratinocyte defense against bacterial infection. J Invest Dermatol. 2008 Aug; 128(8):1964-8. PMID: 18323789.
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    300. Cogen AL, Nizet V, Gallo RL. Skin microbiota: a source of disease or defence? Br J Dermatol. 2008 Mar; 158(3):442-55. PMID: 18275522; PMCID: PMC2746716.
    301. Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 07; 319(5868):1391-4. PMID: 18276850; PMCID: PMC2747771.
    302. Park B, Nizet V, Liu GY. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. J Bacteriol. 2008 Apr; 190(7):2275-8. PMID: 18223076; PMCID: PMC2293205.
    303. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J. 2008 Jun; 22(6):1715-24. PMID: 18198218; PMCID: PMC2721339.
    304. Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes. J Infect Dis. 2008 Jan 15; 197(2):214-7. PMID: 18173364.
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    305. Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, Walker MJ. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. J Biol Chem. 2008 Mar 07; 283(10):6359-66. PMID: 18180300.
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    306. Peyssonnaux C, Nizet V, Johnson RS. Role of the hypoxia inducible factors HIF in iron metabolism. Cell Cycle. 2008 Jan 01; 7(1):28-32. PMID: 18212530.
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    307. Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, Walker MJ. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 2007 Dec; 7(24):4488-98. PMID: 18072207.
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    309. Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorg Med Chem Lett. 2008 May 15; 18(10):3107-11. PMID: 18006314; PMCID: PMC2519147.
    310. Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. CAMP factor is not essential for systemic virulence of Group B Streptococcus. Microb Pathog. 2008 Jan; 44(1):84-8. PMID: 17870297; PMCID: PMC2247369.
    311. Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. J Biol Chem. 2007 Sep 21; 282(38):27562-71. PMID: 17646166; PMCID: PMC2588433.
    312. Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, Henningham A, McArthur JD, Dinkla K, Aziz RK, Kansal RG, Simpson AJ, Buchanan JT, Chhatwal GS, Kotb M, Nizet V. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med. 2007 Aug; 13(8):981-5. PMID: 17632528.
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    313. Bayele HK, Peyssonnaux C, Giatromanolaki A, Arrais-Silva WW, Mohamed HS, Collins H, Giorgio S, Koukourakis M, Johnson RS, Blackwell JM, Nizet V, Srai SK. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood. 2007 Oct 15; 110(8):3039-48. PMID: 17606764.
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    314. Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest. 2007 Jul; 117(7):1926-32. PMID: 17557118; PMCID: PMC1884690.
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    321. Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science. 2006 Dec 15; 314(5806):1792-5. PMID: 17170310.
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    322. Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. J Bacteriol. 2007 Feb; 189(4):1322-9. PMID: 17114267; PMCID: PMC1797346.
    323. Locke JB, Colvin KM, Datta AK, Patel SK, Naidu NN, Neely MN, Nizet V, Buchanan JT. Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. J Bacteriol. 2007 Feb; 189(4):1279-87. PMID: 17098893; PMCID: PMC1797360.
    324. Hamilton A, Popham DL, Carl DJ, Lauth X, Nizet V, Jones AL. Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides. Infect Immun. 2006 Nov; 74(11):6179-87. PMID: 17057092; PMCID: PMC1695509.
    325. Dehority W, Uchiyama S, Khosravi A, Nizet V. Brain abscess caused by Streptococcus pyogenes in a previously healthy child. J Clin Microbiol. 2006 Dec; 44(12):4613-5. PMID: 17065264; PMCID: PMC1698393.
    326. Maisey HC, Hensler M, Nizet V, Doran KS. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. J Bacteriol. 2007 Feb; 189(4):1464-7. PMID: 17041051; PMCID: PMC1797338.
    327. Carlin AF, Lewis AL, Varki A, Nizet V. Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. J Bacteriol. 2007 Feb; 189(4):1231-7. PMID: 16997964; PMCID: PMC1797352.
    328. Hidalgo-Grass C, Mishalian I, Dan-Goor M, Belotserkovsky I, Eran Y, Nizet V, Peled A, Hanski E. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. EMBO J. 2006 Oct 04; 25(19):4628-37. PMID: 16977314; PMCID: PMC1589981.
    329. Timmer AM, Kristian SA, Datta V, Jeng A, Gillen CM, Walker MJ, Beall B, Nizet V. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Mol Microbiol. 2006 Oct; 62(1):15-25. PMID: 16942605.
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    330. Hensler ME, Bernstein G, Nizet V, Nefzi A. Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorg Med Chem Lett. 2006 Oct 01; 16(19):5073-9. PMID: 16890437.
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    332. Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006 Feb 24; 124(4):823-35. PMID: 16497591.
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    334. Lewis AL, Hensler ME, Varki A, Nizet V. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. J Biol Chem. 2006 Apr 21; 281(16):11186-92. PMID: 16490781.
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    336. Nizet V. Antimicrobial peptide resistance mechanisms of human bacterial pathogens. Curr Issues Mol Biol. 2006 Jan; 8(1):11-26. PMID: 16450883.
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    338. Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V. D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol. 2005 Oct; 187(19):6719-25. PMID: 16166534; PMCID: PMC1251589.
    339. Buchanan JT, Stannard JA, Lauth X, Ostland VE, Powell HC, Westerman ME, Nizet V. Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. Infect Immun. 2005 Oct; 73(10):6935-44. PMID: 16177373; PMCID: PMC1230984.
    340. Braff MH, Zaiou M, Fierer J, Nizet V, Gallo RL. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun. 2005 Oct; 73(10):6771-81. PMID: 16177355; PMCID: PMC1230954.
    341. Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest. 2005 Sep; 115(9):2499-507. PMID: 16138192; PMCID: PMC1193870.
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    343. Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005 Jul 18; 202(2):209-15. PMID: 16009720.
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    344. Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest. 2005 Jul; 115(7):1806-15. PMID: 16007254; PMCID: PMC1159132.
    345. Braff MH, Bardan A, Nizet V, Gallo RL. Cutaneous defense mechanisms by antimicrobial peptides. J Invest Dermatol. 2005 Jul; 125(1):9-13. PMID: 15982297.
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    347. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 2005 Apr 28; 434(7037):1138-43. PMID: 15858576.
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    350. Doran KS, Nizet V. Molecular pathogenesis of neonatal group B streptococcal infection: no longer in its infancy. Mol Microbiol. 2004 Oct; 54(1):23-31. PMID: 15458402.
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    352. Lewis AL, Nizet V, Varki A. Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):11123-8. PMID: 15263085; PMCID: PMC503750.
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    354. Bardan A, Nizet V, Gallo RL. Antimicrobial peptides and the skin. Expert Opin Biol Ther. 2004 Apr; 4(4):543-9. PMID: 15102603.
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    355. Hidalgo-Grass C, Dan-Goor M, Maly A, Eran Y, Kwinn LA, Nizet V, Ravins M, Jaffe J, Peyser A, Moses AE, Hanski E. Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections. Lancet. 2004 Feb 28; 363(9410):696-703. PMID: 15001327.
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    356. Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Mol Microbiol. 2004 Jan; 51(1):123-34. PMID: 14651616.
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    357. Saitoh A, Beall B, Nizet V. Fulminant bacterial meningitis complicating sphenoid sinusitis. Pediatr Emerg Care. 2003 Dec; 19(6):415-7. PMID: 14676492.
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    358. Gallo RL, Nizet V. Endogenous production of antimicrobial peptides in innate immunity and human disease. Curr Allergy Asthma Rep. 2003 Sep; 3(5):402-9. PMID: 12906776.
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    359. Doran KS, Liu GY, Nizet V. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest. 2003 Sep; 112(5):736-44. PMID: 12952922; PMCID: PMC182187.
    360. Kristian SA, Lauth X, Nizet V, Goetz F, Neumeister B, Peschel A, Landmann R. Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. J Infect Dis. 2003 Aug 01; 188(3):414-23. PMID: 12870123.
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    361. Zaiou M, Nizet V, Gallo RL. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol. 2003 May; 120(5):810-6. PMID: 12713586.
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    362. Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 2003 Mar 07; 112(5):645-57. PMID: 12628185; PMCID: PMC4480774.
    363. Jeng A, Sakota V, Li Z, Datta V, Beall B, Nizet V. Molecular genetic analysis of a group A Streptococcus operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX. J Bacteriol. 2003 Feb; 185(4):1208-17. PMID: 12562790; PMCID: PMC142848.
    364. Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. Selective modulation of superantigen-induced responses by streptococcal cysteine protease. J Infect Dis. 2003 Feb 01; 187(3):398-407. PMID: 12552423.
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    365. Nizet V, Gallo RL. Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis. 2003; 35(9):670-6. PMID: 14620153.
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    366. Nizet V. Streptococcal beta-hemolysins: genetics and role in disease pathogenesis. Trends Microbiol. 2002 Dec; 10(12):575-80. PMID: 12564994.
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    367. Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and beta-hemolysin/cytolysin. J Infect Dis. 2002 Nov 15; 186(10):1518-21. PMID: 12404173.
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    368. Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. J Immunol. 2002 Oct 01; 169(7):3970-7. PMID: 12244198.
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    369. Fuller JD, Camus AC, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JC. Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun. 2002 Oct; 70(10):5730-9. PMID: 12228303; PMCID: PMC128303.
    370. Nizet V, Gallo RL. Surviving innate immunity. Trends Microbiol. 2002 Aug; 10(8):358-9. PMID: 12160630.
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    371. Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol. 2002 Jun; 22(4):326-30. PMID: 12032798.
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    372. Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. Group B streptococcal beta-hemolysin induces mortality and liver injury in experimental sepsis. J Infect Dis. 2002 Jun 15; 185(12):1745-53. PMID: 12085320.
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    373. Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. Streptolysin S and necrotising infections produced by group G streptococcus. Lancet. 2002 Jan 12; 359(9301):124-9. PMID: 11809255.
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    374. Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis. 2002 Jan 15; 185(2):196-203. PMID: 11807693.
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    375. Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol. 2001 Dec 15; 167(12):7069-76. PMID: 11739528.
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    376. Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15; 277(7):5030-9. PMID: 11739390.
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    377. Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 2001 Nov 22; 414(6862):454-7. PMID: 11719807.
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    378. Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol. 2001 Jul; 117(1):91-7. PMID: 11442754.
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    379. Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: case report and review of the literature. J Infect. 2001 May; 42(4):272-7. PMID: 11545571.
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    380. Fuller JD, Bast DJ, Nizet V, Low DE, de Azavedo JC. Streptococcus iniae virulence is associated with a distinct genetic profile. Infect Immun. 2001 Apr; 69(4):1994-2000. PMID: 11254550; PMCID: PMC98122.
    381. Pritzlaff CA, Chang JC, Kuo SP, Tamura GS, Rubens CE, Nizet V. Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus. Mol Microbiol. 2001 Jan; 39(2):236-47. PMID: 11136446.
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    382. Puliti M, Nizet V, von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. Severity of group B streptococcal arthritis is correlated with beta-hemolysin expression. J Infect Dis. 2000 Sep; 182(3):824-32. PMID: 10950777.
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    384. Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. Group B streptococcal beta-hemolysin induces nitric oxide production in murine macrophages. J Infect Dis. 2000 Jul; 182(1):150-7. PMID: 10882592.
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    385. Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells. Infect Immun. 2000 Feb; 68(2):637-43. PMID: 10639427; PMCID: PMC97186.
    386. Gibson RL, Nizet V, Rubens CE. Group B streptococcal beta-hemolysin promotes injury of lung microvascular endothelial cells. Pediatr Res. 1999 May; 45(5 Pt 1):626-34. PMID: 10231855.
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    389. La Penta D, Framson P, Nizet V, Rubens C. Epithelial cell invasion by group B streptococci is important to virulence. Adv Exp Med Biol. 1997; 418:631-4. PMID: 9331731.
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    391. Mills WJ, Mosca VS, Nizet V. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella. J Pediatr Orthop. 1996 Jul-Aug; 16(4):522-8. PMID: 8784712.
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    392. Brogan TV, Nizet V, Waldhausen JH. Streptococcal skin infections. N Engl J Med. 1996 May 30; 334(22):1478. PMID: 8618597.
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    393. Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. A virulent nonencapsulated Haemophilus influenzae. J Infect Dis. 1996 Jan; 173(1):180-6. PMID: 8537657.
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    395. Nizet V, Priebe CJ. A newborn girl with watery diarrhea, weight loss, and severe metabolic acidosis. Curr Opin Pediatr. 1994 Apr; 6(2):163-7. PMID: 8032396.
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    396. Nizet V, Vinci RJ, Lovejoy FH. Fever in children. Pediatr Rev. 1994 Apr; 15(4):127-35. PMID: 8015996.
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    397. Priebe CJ, Nizet V. A 5-year-old girl with varicella and acute onset of fever, stridor, and respiratory distress. Curr Opin Pediatr. 1994 Feb; 6(1):36-41. PMID: 8205172.
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    398. Priebe CJ, Nizet V. A 7-month-old boy with poor growth, hypercalcemia, and unusual facies. Curr Opin Pediatr. 1993 Dec; 5(6):728-32. PMID: 8124427.
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    399. Priebe CJ, Nizet V. A 2-year-old girl with hematemesis, melena, and splenomegaly. Curr Opin Pediatr. 1993 Oct; 5(5):590-4. PMID: 8287083.
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    400. Lovejoy FH, Nizet V, Priebe CJ. Common etiologies and new approaches to management of poisoning in pediatric practice. Curr Opin Pediatr. 1993 Oct; 5(5):524-30. PMID: 8287075.
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    401. Nizet V, Priebe CJ. An 8-day-old male infant with poor feeding, lethargy, and an elevated anion gap metabolic acidosis. Curr Opin Pediatr. 1993 Aug; 5(4):499-502. PMID: 8374680.
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    402. Palefsky JM, Winkler B, Rabanus JP, Clark C, Chan S, Nizet V, Schoolnik GK. Characterization of in vivo expression of the human papillomavirus type 16 E4 protein in cervical biopsy tissues. J Clin Invest. 1991 Jun; 87(6):2132-41. PMID: 1645754; PMCID: PMC296971.