Martin Paulus

Title(s)Adjunct Professor, Psychiatry
SchoolHealth Sciences
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    Dr. Paulus studied Medicine at the Johannes Gutenberg University in Mainz from 1979-1985. He received a postdoctoral fellowship from the Deutsche Forschungsgemeinschaft (German Research Foundation) in 1986 to study the effects of calcium antagonists on animal models of mania at the University of California San Diego (UCSD). In 1993, Dr. Paulus left UCSD to resume his medical training and completed his internship at the Long Island Jewish Medical Center / Zucker Hillside Hospital on Long Island, NY. In 1994, he rejoined the Department of Psychiatry at UCSD as a psychiatric resident. Dr. Paulus completed his residency in psychiatry in 1997. At that time, he joined the Department of Psychiatry at UCSD as an Assistant Professor. He also became a staff psychiatrist at the Veterans Affairs San Diego Health Care System (VASDHS). Dr. Paulus is currently a Professor in the Department of Psychiatry at UCSD and Director of Telemental Health at the VASDHS, which focuses on delivering evidence based psychotherapy to Operation Enduring Freedom and Operation Iraqi Freedom Veterans with Post-Traumatic Stress Disorder. In May 2014, Dr. Paulus joined the Laureate Institute For Brain Research (LIBR) in Tulsa, OK, as the Scientific Director and President.

    Research Interests

    Dr. Paulus’ research focuses on three main areas:
    (1) Understanding the neurobiology of anxiety disorders and addictive disorders using decision-making and interoception with brain imaging technology.
    (2) Developing tools using neuroscience to make clinically useful predictions for mood, anxiety, and addictive disorders.
    (3) Integrating subjective measurements with neurobiological approaches to understand how psychiatric symptoms emerge from brain dysfunction.

    Dr. Paulus has published over 250 scientific papers, has been funded continuously by federal grants since 1997, and is currently the Principal Investigator on a NIMH R01 aimed at determining the biological basis for positive and negative valence domains in anxiety and depression. He has served on numerous research panels, study sections, and advisory committees. Currently, Dr. Paulus is initiating a large-scale study in Tulsa, termed the T-1000, to determine whether biological measures can be developed to help a clinician predict patient outcomes.

    Clinical Focus

    At the San Diego Veterans Affairs Medical Center, Dr. Paulus, in collaboration with Alby Quinlan, RN, MSN, developed a manualized, structured, multi-modal anger management manual. He regularly teaches an anger management class with Alby Quinlan and has given several clinical presentations on the physical and psychological consequences of anger.

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    The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)
    NIH/NIGMS P20GM121312Sep 15, 2017 - Jun 30, 2022
    Role: Principal Investigator
    ABCD-USA Consortium: Research Project
    NIH/NIDA U01DA041089Sep 30, 2015 - May 31, 2020
    Role: Principal Investigator
    Latent Constructs: Negative-Positive Valence Domains in Anxiety and Depression
    NIH/NIMH R01MH101453Sep 9, 2013 - May 31, 2017
    Role: Principal Investigator
    Does amphetamine use impair brain systems in OEF/OIF veterans with PTSD?
    VA I01CX000273Oct 1, 2011 - Sep 30, 2015
    Role: Principal Investigator
    Center on Interoceptive Dysregulation in Addiction (CIDIA)
    NIH/NIDA P20DA027843Mar 15, 2010 - Feb 28, 2014
    Role: Principal Investigator
    Negative reinforcement and interoceptive dysfunction in stimulant dependence.
    NIH/NIDA R01DA027797Sep 1, 2009 - Jul 31, 2014
    Role: Principal Investigator
    Time processing in stimulant users: Impulsivity and temporal discounting
    NIH/NIDA R03DA020687Jul 20, 2007 - Jun 30, 2010
    Role: Principal Investigator
    NIH/NIDA R01DA018307Sep 30, 2004 - Jun 30, 2010
    Role: Principal Investigator
    Neurobiology Of Transition To Stimulant Dependence
    NIH/NIDA R01DA016663Apr 1, 2004 - Mar 31, 2009
    Role: Principal Investigator
    NIH/NIDA R21DA013186Apr 10, 2001 - Mar 31, 2005
    Role: Principal Investigator
    MDMA &Amphetamine--Behavioral Organization in Mice
    NIH/NIDA R21DA014200Apr 1, 2001 - Mar 31, 2005
    Role: Principal Investigator
    NIH/NIMH R03MH058358May 1, 1998 - Apr 30, 2001
    Role: Principal Investigator
    NIH/NIDA R01DA011277Sep 30, 1997 - Jul 31, 2001
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Jan 27, 1997 - Nov 30, 2010
    Role: Co-Investigator
    Fellowship on Biological Psychiatry and Neuroscience
    NIH/NIMH T32MH018399Jul 15, 1986 - Jun 30, 2022
    Role: Principal Investigator

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