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Christopher Glass

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentCellular and Molecular Medicine
Address9500 Gilman Drive #0651
La Jolla CA 92093
Phone858-534-6011
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    Collapse Overview 
    Collapse Overview
    Dr. Glass’ primary interests are to understand the mechanisms by which sequence-specific transcription factors, co-activators and co-repressors regulate the development and function of macrophages. A major direction of his laboratory has been to define the genome-wide locations and functions of these proteins through the use of assays that are based on massively parallel DNA sequencing. The combination of these technologies with molecular, genetic, lipidomic and cell-based approaches is providing new insights into mechanisms that regulate macrophage gene expression and function that are relevant to inflammatory diseases that include diabetes, atherosclerosis and neurodegenerative diseases.

    Research Focus Areas:



    Collapse Research 
    Collapse Research Activities and Funding
    The Enhancer Code of AD-A Genetic Approach
    NIH/NIA R01AG056511Aug 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Combinatorial Actions of Genetic Variants and Gender Bias of Alzherimer's Disease
    NIH/NIA R01AG057706Sep 30, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Mechanisms controlling human microglia gene expression
    NIH/NINDS R01NS096170May 15, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Enhancer Therapy
    NIH/NCI R01CA173903Sep 12, 2012 - Jul 31, 2017
    Role: Principal Investigator
    San Diego Center for Systems Biology: From Maps to Models
    NIH/NIGMS P50GM085764Jul 1, 2008 - May 31, 2019
    Role: Co-Investigator
    PPARgamma, Toll-like receptors, and atherosclerosis
    NIH/NHLBI R01HL088129May 1, 2007 - Apr 30, 2008
    Role: Principal Investigator
    Role of Immune Mechanisms in Athersclerosis and Inflammation
    NIH/NHLBI P01HL088093Apr 1, 2007 - Apr 30, 2019
    Role: Co-Investigator
    Gene Networks controlling macrophage-adipocyte interactions in insulin
    NIH/NIDDK P01DK074868Apr 1, 2006 - Apr 30, 2017
    Role: Principal Investigator
    Conference on PPAR/LXR
    NIH/NIDDK R13DK070428Sep 20, 2004 - Aug 31, 2005
    Role: Principal Investigator
    LIPID MAPS
    NIH/NIGMS U54GM069338Aug 12, 2003 - Jul 31, 2014
    Role: Co-Investigator
    Diabetes Research Center (DRC)
    NIH/NIDDK P30DK063491Dec 1, 2002 - Apr 30, 2018
    Role: Co-Investigator
    Nuclear Receptors and Coregulators in Health and Disease
    NIH U19DK062434Aug 15, 2002 - Jul 31, 2012
    Role: Co-Investigator
    Gordon Research Conference: Mechanisms of Hormone Action
    NIH/NIDDK R13DK061960Jun 15, 2002 - Jul 31, 2005
    Role: Principal Investigator
    Summer Undergraduate Research Fellowship (SURF)
    NIH/NHLBI T35HL067694May 21, 2001 - Apr 30, 2006
    Role: Principal Investigator
    DETECTION AND MODELS OF TOXICANT EXPOSURE
    NIH/NIEHS P42ES010337Jul 1, 2000 - Mar 31, 2022
    Role: Co-Investigator
    CDNA MICROARRAYER AND SCANNING CONFOCAL LASER READER
    NIH/NCRR S10RR014881Apr 1, 2000 - Mar 31, 2001
    Role: Principal Investigator
    Integration of transcriptional responses in macrophages
    NIH/NHLBI R01HL059694Jan 1, 1998 - Dec 31, 2008
    Role: Principal Investigator
    SCOR in Molecular Medicine and Atherosclerosis
    NIH/NHLBI P50HL056989Apr 23, 1997 - Mar 31, 2008
    Role: Co-Investigator
    Transcriptional co-regulators and macrophage gene expression
    NIH/NIDDK R01DK091183Apr 1, 1991 - Jan 31, 2020
    Role: Principal Investigator
    Transcriptional Co-Regulators and Macrophage Gene Expression
    NIH/NCI R01CA052599Apr 1, 1991 - Mar 31, 2011
    Role: Principal Investigator
    CELL-SPECIFIC EXPRESSION OF GROWTH HORMONE AND PROLACTIN
    NIH/NIDDK F32DK007959Mar 1, 1987
    Role: Principal Investigator
    TRAINING GRANT IN MOLECULAR MEDICINE AND ATHEROSCLEROSIS
    NIH/NHLBI T32HL007276Jul 1, 1977 - Nov 12, 2005
    Role: Principal Investigator
    SCOR IN ARTERIOSCLEROSIS
    NIH P50HL014197Dec 1, 1976 - Apr 30, 1997
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Carlin AF, Vizcarra EA, Branche E, Viramontes KM, Suarez-Amaran L, Ley K, Heinz S, Benner C, Shresta S, Glass CK. Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. Proc Natl Acad Sci U S A. 2018 Sep 11. PMID: 30206152.
      View in: PubMed
    2. Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J. A monocyte gene expression signature in the early clinical course of Parkinson's disease. Sci Rep. 2018 Jul 17; 8(1):10757. PMID: 30018301.
      View in: PubMed
    3. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 Jul 16. PMID: 30013121.
      View in: PubMed
    4. Link VM, Romanoski CE, Metzler D, Glass CK. MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements. Nucleic Acids Res. 2018 Jun 09. PMID: 29893919.
      View in: PubMed
    5. Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. 2018 Jun 06. PMID: 29875409.
      View in: PubMed
    6. Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Rep. 2018 May 29; 23(9):2550-2558. PMID: 29847787.
      View in: PubMed
    7. Link VM, Duttke SH, Chun HB, Holtman IR, Westin E, Hoeksema MA, Abe Y, Skola D, Romanoski CE, Tao J, Fonseca GJ, Troutman TD, Spann NJ, Strid T, Sakai M, Yu M, Hu R, Fang R, Metzler D, Ren B, Glass CK. Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function. Cell. 2018 May 05. PMID: 29779944.
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    8. Fei J, Ishii H, Hoeksema MA, Meitinger F, Kassavetis GA, Glass CK, Ren B, Kadonaga JT. NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes. Genes Dev. 2018 May 01; 32(9-10):682-694. PMID: 29759984.
      View in: PubMed
    9. Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, Tremblay MS, Glass CK. Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proc Natl Acad Sci U S A. 2018 May 15; 115(20):E4680-E4689. PMID: 29632203.
      View in: PubMed
    10. Nott A, Glass CK. Immune memory in the brain. Nature. 2018 Apr; 556(7701):312-313. PMID: 29662132.
      View in: PubMed
    11. Neal S, Jaeger PA, Duttke SH, Benner C, Glass CK, Ideker T, Hampton RY. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell. 2018 Mar 01; 69(5):915. PMID: 29499140.
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    12. Prohaska TA, Que X, Diehl CJ, Hendrikx S, Chang MW, Jepsen K, Glass CK, Benner C, Witztum JL. Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies. J Immunol. 2018 Mar 01; 200(5):1702-1717. PMID: 29378911.
      View in: PubMed
    13. Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, Glass CK, Rosenfeld MG. Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018 Jan 09; 115(2):E244-E252. PMID: 29263096.
      View in: PubMed
    14. Carlin AF, Plummer EM, Vizcarra EA, Sheets N, Joo Y, Tang W, Day J, Greenbaum J, Glass CK, Diamond MS, Shresta S. An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses. Cell Rep. 2017 Nov 07; 21(6):1600-1612. PMID: 29117564.
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    15. Pirzgalska RM, Seixas E, Seidman JS, Link VM, Sánchez NM, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass CK, Domingos AI. Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine. Nat Med. 2017 Nov; 23(11):1309-1318. PMID: 29035364.
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    16. Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK, Lauberth SM. Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling. Nat Commun. 2017 09 29; 8(1):754. PMID: 28963538.
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    17. Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346. PMID: 28970240.
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    18. Holtman IR, Skola D, Glass CK. Transcriptional control of microglia phenotypes in health and disease. J Clin Invest. 2017 Sep 01; 127(9):3220-3229. PMID: 28758903.
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    19. Hogan NT, Whalen MB, Stolze LK, Hadeli NK, Lam MT, Springstead JR, Glass CK, Romanoski CE. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife. 2017 06 06; 6. PMID: 28585919.
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    20. Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. An environment-dependent transcriptional network specifies human microglia identity. Science. 2017 06 23; 356(6344). PMID: 28546318.
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    21. Phan AT, Goldrath AW, Glass CK. Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity. Immunity. 2017 05 16; 46(5):714-729. PMID: 28514673.
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    22. Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, Lin CY, Frasor J, Nettles KW, Glass CK. Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Mol Cell. 2017 Mar 16; 65(6):1122-1135.e5. PMID: 28306507.
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    23. Okerblom JJ, Schwarz F, Olson J, Fletes W, Ali SR, Martin PT, Glass CK, Nizet V, Varki A. Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. J Immunol. 2017 03 15; 198(6):2366-2373. PMID: 28148732.
      View in: PubMed
    24. Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab. 2017 Feb 07; 25(2):412-427. PMID: 28041958.
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    25. Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC. Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function. Immunity. 2016 11 15; 45(5):975-987. PMID: 27814941.
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    26. Fonseca GJ, Seidman JS, Glass CK. Genome-Wide Approaches to Defining Macrophage Identity and Function. Microbiol Spectr. 2016 10; 4(5). PMID: 28087927.
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    27. Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. Tissue damage drives co-localization of NF-?B, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 2016 07 27; 5. PMID: 27462873; PMCID: PMC4963201.
    28. Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK, Oegema K. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66. PMID: 27432897.
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    29. Allison KA, Sajti E, Collier JG, Gosselin D, Troutman TD, Stone EL, Hedrick SM, Glass CK. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. Elife. 2016 07 04; 5. PMID: 27376549; PMCID: PMC4931909.
    30. Yu S, Li S, Henke A, Muse ED, Cheng B, Welzel G, Chatterjee AK, Wang D, Roland J, Glass CK, Tremblay M. Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases. FASEB J. 2016 07; 30(7):2570-9. PMID: 27025962; PMCID: PMC4904286 [Available on 07/01/17].
    31. Glass CK, Natoli G. Molecular control of activation and priming in macrophages. Nat Immunol. 2016 Jan; 17(1):26-33. PMID: 26681459; PMCID: PMC4795476.
    32. Link VM, Gosselin D, Glass CK. Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers. Cold Spring Harb Symp Quant Biol. 2015; 80:213-21. PMID: 26582787; PMCID: PMC4936825.
    33. Duttke SH, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. Perspectives on Unidirectional versus Divergent Transcription. Mol Cell. 2015 Nov 05; 60(3):348-9. PMID: 26545075; PMCID: PMC4643650 [Available on 11/05/16].
    34. Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation. Nat Immunol. 2015 Dec; 16(12):1228-34. PMID: 26523867; PMCID: PMC4833087.
    35. Romanoski CE, Link VM, Heinz S, Glass CK. Exploiting genomics and natural genetic variation to decode macrophage enhancers. Trends Immunol. 2015 Sep; 36(9):507-18. PMID: 26298065; PMCID: PMC4548828.
    36. Glass CK, Witztum JL. Daniel Steinberg, 1922-2015. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):9791-2. PMID: 26209653; PMCID: PMC4538637.
    37. Liang X, Zhang Q, Cattaneo P, Zhuang S, Gong X, Spann NJ, Jiang C, Cao X, Zhao X, Zhang X, Bu L, Wang G, Chen HS, Zhuang T, Yan J, Geng P, Luo L, Banerjee I, Chen Y, Glass CK, Zambon AC, Chen J, Sun Y, Evans SM. Transcription factor ISL1 is essential for pacemaker development and function. J Clin Invest. 2015 Aug 03; 125(8):3256-68. PMID: 26193633; PMCID: PMC4563735.
    38. Crotti A, Glass CK. The choreography of neuroinflammation in Huntington's disease. Trends Immunol. 2015 Jun; 36(6):364-73. PMID: 26001312; PMCID: PMC4786070.
    39. Schwarz F, Pearce OM, Wang X, Samraj AN, Läubli H, Garcia JO, Lin H, Fu X, Garcia-Bingman A, Secrest P, Romanoski CE, Heyser C, Glass CK, Hazen SL, Varki N, Varki A, Gagneux P. Siglec receptors impact mammalian lifespan by modulating oxidative stress. Elife. 2015 Apr 07; 4. PMID: 25846707; PMCID: PMC4384638.
    40. Glass CK. Genetic and genomic approaches to understanding macrophage identity and function. Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4):755-62. PMID: 25745059; PMCID: PMC4376616.
    41. Romanoski CE, Glass CK, Stunnenberg HG, Wilson L, Almouzni G. Epigenomics: Roadmap for regulation. Nature. 2015 Feb 19; 518(7539):314-6. PMID: 25693562.
      View in: PubMed
    42. Heinz S, Romanoski CE, Benner C, Glass CK. The selection and function of cell type-specific enhancers. Nat Rev Mol Cell Biol. 2015 Mar; 16(3):144-54. PMID: 25650801; PMCID: PMC4517609.
    43. Duttke SHC, Lacadie SA, Ibrahim MM, Glass CK, Corcoran DL, Benner C, Heinz S, Kadonaga JT, Ohler U. Human promoters are intrinsically directional. Mol Cell. 2015 Feb 19; 57(4):674-684. PMID: 25639469.
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    44. Gorden DL, Myers DS, Ivanova PT, Fahy E, Maurya MR, Gupta S, Min J, Spann NJ, McDonald JG, Kelly SL, Duan J, Sullards MC, Leiker TJ, Barkley RM, Quehenberger O, Armando AM, Milne SB, Mathews TP, Armstrong MD, Li C, Melvin WV, Clements RH, Washington MK, Mendonsa AM, Witztum JL, Guan Z, Glass CK, Murphy RC, Dennis EA, Merrill AH, Russell DW, Subramaniam S, Brown HA. Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. J Lipid Res. 2015 Mar; 56(3):722-36. PMID: 25598080; PMCID: PMC4340319.
    45. Davis-Turak JC, Allison K, Shokhirev MN, Ponomarenko P, Tsimring LS, Glass CK, Johnson TL, Hoffmann A. Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing. Nucleic Acids Res. 2015 Jan; 43(2):699-707. PMID: 25541195; PMCID: PMC4333389.
    46. Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, Stender JD, Chun HB, Garner H, Geissmann F, Glass CK. Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell. 2014 Dec 04; 159(6):1327-40. PMID: 25480297.
      View in: PubMed
    47. Gordts PLSM, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. Cell Metab. 2014 Nov 04; 20(5):813-826. PMID: 25440058.
      View in: PubMed
    48. Gosselin D, Glass CK. Epigenomics of macrophages. Immunol Rev. 2014 Nov; 262(1):96-112. PMID: 25319330; PMCID: PMC4203424.
    49. Kaikkonen MU, Niskanen H, Romanoski CE, Kansanen E, Kivelä AM, Laitalainen J, Heinz S, Benner C, Glass CK, Ylä-Herttuala S. Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization. Nucleic Acids Res. 2014 Nov 10; 42(20):12570-84. PMID: 25352550; PMCID: PMC4227755.
    50. Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):E3957-65. PMID: 25201979; PMCID: PMC4183331.
    51. Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions. EMBO Mol Med. 2014 Sep; 6(9):1124-32. PMID: 25007801; PMCID: PMC4197860.
    52. Norris PC, Gosselin D, Reichart D, Glass CK, Dennis EA. Phospholipase A2 regulates eicosanoid class switching during inflammasome activation. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):12746-51. PMID: 25139986; PMCID: PMC4156727.
    53. Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T. Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3297-305. PMID: 25074909; PMCID: PMC4136601.
    54. Lam MT, Li W, Rosenfeld MG, Glass CK. Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci. 2014 Apr; 39(4):170-82. PMID: 24674738; PMCID: PMC4266492.
    55. Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nat Neurosci. 2014 Apr; 17(4):513-21. PMID: 24584051.
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    56. Kihara Y, Gupta S, Maurya MR, Armando A, Shah I, Quehenberger O, Glass CK, Dennis EA, Subramaniam S. Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases. Biophys J. 2014 Feb 18; 106(4):966-75. PMID: 24559999; PMCID: PMC3945033.
    57. Allison KA, Kaikkonen MU, Gaasterland T, Glass CK. Vespucci: a system for building annotated databases of nascent transcripts. Nucleic Acids Res. 2014 Feb; 42(4):2433-47. PMID: 24304890; PMCID: PMC3936758.
    58. Zhang DX, Glass CK. Towards an understanding of cell-specific functions of signal-dependent transcription factors. J Mol Endocrinol. 2013 Dec; 51(3):T37-50. PMID: 24130129; PMCID: PMC4128342.
    59. Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23. PMID: 24189069; PMCID: PMC3861632.
    60. Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 2013 Sep 26; 155(1):200-214. PMID: 24074869; PMCID: PMC4131699.
    61. Spann NJ, Glass CK. Sterols and oxysterols in immune cell function. Nat Immunol. 2013 Sep; 14(9):893-900. PMID: 23959186.
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    62. Dinasarapu AR, Gupta S, Ram Maurya M, Fahy E, Min J, Sud M, Gersten MJ, Glass CK, Subramaniam S. A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism. Bioinformatics. 2013 Nov 01; 29(21):2735-43. PMID: 23981351; PMCID: PMC3799469.
    63. McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O. Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid. EMBO Mol Med. 2013 Sep; 5(9):1443-57. PMID: 23964012; PMCID: PMC3799497.
    64. Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, Chun HB, Tough DF, Prinjha RK, Benner C, Glass CK. Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell. 2013 Aug 08; 51(3):310-25. PMID: 23932714; PMCID: PMC3779836.
    65. Stender JD, Glass CK. Epigenomic control of the innate immune response. Curr Opin Pharmacol. 2013 Aug; 13(4):582-7. PMID: 23816801.
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    66. Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S. Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. J Lipid Res. 2013 Sep; 54(9):2525-42. PMID: 23776196; PMCID: PMC3735949.
    67. Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim HS, Glass CK, Rosenfeld MG. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 2013 Jun 27; 498(7455):516-20. PMID: 23728302; PMCID: PMC3718886.
    68. Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 2013 Jun 27; 498(7455):511-5. PMID: 23728303; PMCID: PMC3839578.
    69. Xie L, Sullivan AL, Collier JG, Glass CK. Serum response factor indirectly regulates type I interferon-signaling in macrophages. J Interferon Cytokine Res. 2013 Oct; 33(10):588-96. PMID: 23705899; PMCID: PMC3793656.
    70. Sever R, Glass CK. Signaling by nuclear receptors. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a016709. PMID: 23457262; PMCID: PMC3578364.
    71. Tabas I, Glass CK. Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science. 2013 Jan 11; 339(6116):166-72. PMID: 23307734; PMCID: PMC3608517.
    72. Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity. 2013 Jan 24; 38(1):106-18. PMID: 23273843; PMCID: PMC3556782.
    73. Mansson R, Welinder E, Åhsberg J, Lin YC, Benner C, Glass CK, Lucas JS, Sigvardsson M, Murre C. Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21028-33. PMID: 23213261; PMCID: PMC3529039.
    74. Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C. Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol. 2012 Dec; 13(12):1196-204. PMID: 23064439; PMCID: PMC3501570.
    75. Hu Q, Tanasa B, Trabucchi M, Li W, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation. Nat Struct Mol Biol. 2012 Nov; 19(11):1168-75. PMID: 23064648; PMCID: PMC3743530.
    76. Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G. The transcriptional specificity of NF-?B dimers is coded within the ?B DNA response elements. Cell Rep. 2012 Oct 25; 2(4):824-39. PMID: 23063365; PMCID: PMC4167904.
    77. Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52. PMID: 23021221; PMCID: PMC3464914.
    78. Saijo K, Crotti A, Glass CK. Regulation of microglia activation and deactivation by nuclear receptors. Glia. 2013 Jan; 61(1):104-11. PMID: 22987512.
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    79. Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell. 2012 Oct 12; 48(1):28-38. PMID: 22921934; PMCID: PMC3472359.
    80. Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9448-53. PMID: 22566629; PMCID: PMC3386114.
    81. Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 2012 May 02; 15(5):635-45. PMID: 22560216; PMCID: PMC4156155.
    82. Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. Regulation of circadian behaviour and metabolism by REV-ERB-a and REV-ERB-ß. Nature. 2012 Mar 29; 485(7396):123-7. PMID: 22460952; PMCID: PMC3367514.
    83. Papac-Milicevic N, Breuss JM, Zaujec J, Ryban L, Plyushch T, Wagner GA, Fenzl S, Dremsek P, Cabaravdic M, Steiner M, Glass CK, Binder CJ, Uhrin P, Binder BR. The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors. Circ Res. 2012 Apr 13; 110(8):e50-63. PMID: 22427340.
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    84. Cardamone MD, Krones A, Tanasa B, Taylor H, Ricci L, Ohgi KA, Glass CK, Rosenfeld MG, Perissi V. A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2. Mol Cell. 2012 Apr 13; 46(1):91-104. PMID: 22424771; PMCID: PMC3327812.
    85. Heinz S, Glass CK. Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies. Curr Top Microbiol Immunol. 2012; 356:1-15. PMID: 21744305.
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    86. Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. Peroxisome proliferator-activated receptor-? agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 2012 Mar 01; 302(5):F540-51. PMID: 22169011; PMCID: PMC3353644.
    87. Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 2011 Dec; 7(12):e1002401. PMID: 22174696; PMCID: PMC3234212.
    88. Saijo K, Glass CK. Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol. 2011 Oct 25; 11(11):775-87. PMID: 22025055.
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    89. Harmon GS, Lam MT, Glass CK. PPARs and lipid ligands in inflammation and metabolism. Chem Rev. 2011 Oct 12; 111(10):6321-40. PMID: 21988241; PMCID: PMC3437919.
    90. Garmire LX, Garmire DG, Huang W, Yao J, Glass CK, Subramaniam S. A global clustering algorithm to identify long intergenic non-coding RNA--with applications in mouse macrophages. PLoS One. 2011; 6(9):e24051. PMID: 21980340; PMCID: PMC3184070.
    91. Mercer EM, Lin YC, Benner C, Jhunjhunwala S, Dutkowski J, Flores M, Sigvardsson M, Ideker T, Glass CK, Murre C. Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity. 2011 Sep 23; 35(3):413-25. PMID: 21903424; PMCID: PMC3183365.
    92. Norris PC, Reichart D, Dumlao DS, Glass CK, Dennis EA. Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype. J Leukoc Biol. 2011 Sep; 90(3):563-74. PMID: 21653236; PMCID: PMC3157897.
    93. Ylä-Herttuala S, Glass CK. Review focus on epigenetics and the histone code in vascular biology. Cardiovasc Res. 2011 Jun 01; 90(3):402-3. PMID: 21586445; PMCID: PMC3096309.
    94. Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T. Migration of fibrocytes in fibrogenic liver injury. Am J Pathol. 2011 Jul; 179(1):189-98. PMID: 21703401; PMCID: PMC3123781.
    95. Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD. Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011 May 15; 474(7351):390-4. PMID: 21572438; PMCID: PMC3117022.
    96. Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. An ADIOL-ERß-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell. 2011 May 13; 145(4):584-95. PMID: 21565615; PMCID: PMC3433492.
    97. Kaikkonen MU, Lam MT, Glass CK. Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res. 2011 Jun 01; 90(3):430-40. PMID: 21558279; PMCID: PMC3096308.
    98. Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl). 2011 Oct; 89(10):997-1013. PMID: 21499735; PMCID: PMC3171633.
    99. Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8. PMID: 21331046; PMCID: PMC3464905.
    100. Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S. Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism. BMC Syst Biol. 2011 Feb 08; 5:26. PMID: 21303545; PMCID: PMC3047436.
    101. Diehl CJ, Barish GD, Downes M, Chou MY, Heinz S, Glass CK, Evans RM, Witztum JL. Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells. Mol Endocrinol. 2011 Mar; 25(3):529-45. PMID: 21273443; PMCID: PMC3045740.
    102. Wang X, Song X, Glass CK, Rosenfeld MG. The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a003756. PMID: 20573714; PMCID: PMC3003465.
    103. Sullivan AL, Benner C, Heinz S, Huang W, Xie L, Miano JM, Glass CK. Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol. 2011 Feb; 31(4):861-75. PMID: 21135125; PMCID: PMC3028656.
    104. Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010 Nov 18; 8(5):445-54. PMID: 21075355; PMCID: PMC3008410.
    105. Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J. 2010 Dec 15; 29(24):4223-36. PMID: 21045807; PMCID: PMC3018786.
    106. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17; 285(51):39976-85. PMID: 20923771; PMCID: PMC3000979.
    107. Sims K, Haynes CA, Kelly S, Allegood JC, Wang E, Momin A, Leipelt M, Reichart D, Glass CK, Sullards MC, Merrill AH. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem. 2010 Dec 03; 285(49):38568-79. PMID: 20876532; PMCID: PMC2992289.
    108. Shibata N, Glass CK. Macrophages, oxysterols and atherosclerosis. Circ J. 2010 Oct; 74(10):2045-51. PMID: 20838002.
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    109. Oishi-Tanaka Y, Glass CK. A new role for cyclic phosphatidic acid as a PPARgamma antagonist. Cell Metab. 2010 Sep 08; 12(3):207-8. PMID: 20816085.
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    110. Flammer JR, Dobrovolna J, Kennedy MA, Chinenov Y, Glass CK, Ivashkiv LB, Rogatsky I. The type I interferon signaling pathway is a target for glucocorticoid inhibition. Mol Cell Biol. 2010 Oct; 30(19):4564-74. PMID: 20679482; PMCID: PMC2950533.
    111. Huang W, Glass CK. Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8):1542-9. PMID: 20631355; PMCID: PMC2911147.
    112. Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12. PMID: 20622854; PMCID: PMC3059551.
    113. Stender JD, Kim K, Charn TH, Komm B, Chang KC, Kraus WL, Benner C, Glass CK, Katzenellenbogen BS. Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol Cell Biol. 2010 Aug; 30(16):3943-55. PMID: 20547749; PMCID: PMC2916448.
    114. Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol. 2010 Jul; 11(7):635-43. PMID: 20543837; PMCID: PMC2896911.
    115. Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell. 2010 May 28; 38(4):576-89. PMID: 20513432; PMCID: PMC2898526.
    116. Kadandale P, Stender JD, Glass CK, Kiger AA. Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10502-7. PMID: 20498061; PMCID: PMC2890812.
    117. Núñez V, Alameda D, Rico D, Mota R, Gonzalo P, Cedenilla M, Fischer T, Boscá L, Glass CK, Arroyo AG, Ricote M. Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10626-31. PMID: 20498053; PMCID: PMC2890831.
    118. Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia. Circ Res. 2010 Jul 09; 107(1):56-65. PMID: 20489162; PMCID: PMC2904601.
    119. Glass CK, Saijo K. Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells. Nat Rev Immunol. 2010 May; 10(5):365-76. PMID: 20414208.
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    120. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. Mechanisms underlying inflammation in neurodegeneration. Cell. 2010 Mar 19; 140(6):918-34. PMID: 20303880; PMCID: PMC2873093.
    121. Harmon GS, Dumlao DS, Ng DT, Barrett KE, Dennis EA, Dong H, Glass CK. Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice. Nat Med. 2010 Mar; 16(3):313-8. PMID: 20154695; PMCID: PMC2834836.
    122. Perissi V, Jepsen K, Glass CK, Rosenfeld MG. Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet. 2010 Feb; 11(2):109-23. PMID: 20084085.
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    123. Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol. 2010; 72:219-46. PMID: 20148674.
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    124. Saijo K, Crotti A, Glass CK. Nuclear receptors, inflammation, and neurodegenerative diseases. Adv Immunol. 2010; 106:21-59. PMID: 20728023.
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    125. Garmire LX, Shen Z, Briggs S, Yeo G, Subramaniam S, Glass C. Regulatory network of microRNAs in RAW 264.7 macrophage cells. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6198-201. PMID: 21097158.
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    126. Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell. 2009 Dec 11; 139(6):1069-83. PMID: 19962179; PMCID: PMC2812435.
    127. Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Nowak N, Novak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, Knolle PA. The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med. 2009 Sep 28; 206(10):2079-89. PMID: 19737866; PMCID: PMC2757877.
    128. Turunen MP, Lehtola T, Heinonen SE, Assefa GS, Korpisalo P, Girnary R, Glass CK, Väisänen S, Ylä-Herttuala S. Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ Res. 2009 Sep 11; 105(6):604-9. PMID: 19696410.
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    129. Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell. 2009 Jul 10; 35(1):48-57. PMID: 19595715; PMCID: PMC2759189.
    130. Kurokawa R, Rosenfeld MG, Glass CK. Transcriptional regulation through noncoding RNAs and epigenetic modifications. RNA Biol. 2009 Jul-Aug; 6(3):233-6. PMID: 19411842.
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    131. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650; PMCID: PMC2691684.
    132. Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell. 2009 Apr 03; 137(1):47-59. PMID: 19345186; PMCID: PMC2754279.
    133. Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93. PMID: 19299558; PMCID: PMC2661610.
    134. Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature. 2009 Apr 02; 458(7238):591-6. PMID: 19234442; PMCID: PMC2692521.
    135. Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A. 2008 12 09; 105(49):19199-204. PMID: 19052240.
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    136. Shibata N, Glass CK. Regulation of macrophage function in inflammation and atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S277-81. PMID: 18987388; PMCID: PMC2674700.
    137. Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J Med Chem. 2008 Sep 25; 51(18):5758-65. PMID: 18800767.
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    138. Glass CK, Saijo K. Immunology: Oxysterols hold T cells in check. Nature. 2008 Sep 04; 455(7209):40-1. PMID: 18769427.
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    139. Steinberg D, Glass CK, Witztum JL. Evidence mandating earlier and more aggressive treatment of hypercholesterolemia. Circulation. 2008 Aug 05; 118(6):672-7. PMID: 18678783.
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    140. Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Jul 11; 134(1):189. PMID: 18630350.
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    141. Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG, Glass CK, Kurokawa R. Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature. 2008 Jul 03; 454(7200):126-30. PMID: 18509338; PMCID: PMC2823488.
    142. Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, Saijo K, Glass CK, Hume DA, Kellie S, Sweet MJ. Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res. 2008 Apr 29; 4:5. PMID: 18442421; PMCID: PMC2394514.
    143. Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66. PMID: 18374649; PMCID: PMC2364611.
    144. Nunez E, Kwon YS, Hutt KR, Hu Q, Cardamone MD, Ohgi KA, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG, Fu XD. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell. 2008 Mar 21; 132(6):996-1010. PMID: 18358812.
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    145. Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG. Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell. 2008 Jan 18; 29(1):69-80. PMID: 18206970; PMCID: PMC2327256.
    146. Straus DS, Glass CK. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol. 2007 Dec; 28(12):551-8. PMID: 17981503.
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    147. Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG. SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15; 450(7168):415-9. PMID: 17928865.
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    148. Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem. 2007 Nov 30; 282(48):35279-92. PMID: 17916553.
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    149. Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, Erdjument-Bromage H, Tempst P, Glass CK, Rosenfeld MG. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell. 2007 Aug 17; 27(4):609-21. PMID: 17707232; PMCID: PMC2709280.
    150. Lunyak VV, Prefontaine GG, Núñez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, García-Díaz A, Zhu X, Yung Y, Montoliu L, Glass CK, Rosenfeld MG. Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science. 2007 Jul 13; 317(5835):248-51. PMID: 17626886.
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    151. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816. PMID: 17571346.
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    152. Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007 Jun; 117(6):1658-69. PMID: 17525798; PMCID: PMC1868788.
    153. Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK. Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS. Cell Cycle. 2007 Jul 01; 6(13):1594-604. PMID: 17525531.
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    154. Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG. Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19; 446(7138):882-7. PMID: 17392792.
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    155. Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M, Fan JB, Duan L, Glass CK, Rosenfeld MG, Fu XD. Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):4852-7. PMID: 17360330; PMCID: PMC1821125.
    156. Ricote M, Glass CK. PPARs and molecular mechanisms of transrepression. Biochim Biophys Acta. 2007 Aug; 1771(8):926-35. PMID: 17433773; PMCID: PMC1986735.
    157. Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS, Ju BG, Ohgi KA, Wang J, Escoubet-Lozach L, Rose DW, Glass CK, Fu XD, Rosenfeld MG. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell. 2007 Feb 09; 128(3):505-518. PMID: 17289570; PMCID: PMC1994663.
    158. Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK. Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007 Jan 12; 25(1):57-70. PMID: 17218271; PMCID: PMC1850387.
    159. Maurya MR, Benner C, Pradervand S, Glass C, Subramaniam S. Systems biology of macrophages. Adv Exp Med Biol. 2007; 598:62-79. PMID: 17892205.
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    160. Pascual G, Sullivan AL, Ogawa S, Gamliel A, Perissi V, Rosenfeld MG, Glass CK. Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Found Symp. 2007; 286:183-96; discussion 196-203. PMID: 18269183.
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    161. Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, Grimaldi PA, Kadowaki T, Lazar MA, O'Rahilly S, Palmer CN, Plutzky J, Reddy JK, Spiegelman BM, Staels B, Wahli W. International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev. 2006 Dec; 58(4):726-41. PMID: 17132851.
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    162. Liddiard K, Welch JS, Lozach J, Heinz S, Glass CK, Greaves DR. Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter. BMC Mol Biol. 2006 Nov 29; 7:45. PMID: 17134490; PMCID: PMC1698493.
    163. Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Subramaniam S. LMSD: LIPID MAPS structure database. Nucleic Acids Res. 2007 Jan; 35(Database issue):D527-32. PMID: 17098933; PMCID: PMC1669719.
    164. Pascual G, Glass CK. Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol Metab. 2006 Oct; 17(8):321-7. PMID: 16942889.
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    165. Ricote M, Snyder CS, Leung HY, Chen J, Chien KR, Glass CK. Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells. J Leukoc Biol. 2006 Oct; 80(4):850-61. PMID: 16888087.
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    166. Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG. A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science. 2006 Jun 23; 312(5781):1798-802. PMID: 16794079.
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    167. Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 2006 Jun 01; 20(11):1405-28. PMID: 16751179.
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    168. Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A. Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Res. 2006 Jun 01; 66(11):5565-73. PMID: 16740691.
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    169. Glass CK. Going nuclear in metabolic and cardiovascular disease. J Clin Invest. 2006 Mar; 116(3):556-60. PMID: 16511587; PMCID: PMC1386116.
    170. Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC, Buczynski MW, Cooper JA, Deems RA, Dennis EA. Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res. 2006 May; 47(5):1097-111. PMID: 16479018.
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    171. Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H, Akira S, Kotol PF, Glass CK, Rosenfeld MG, Rose DW. Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell. 2006 Feb 10; 124(3):615-29. PMID: 16469706.
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    172. Glass CK, Ogawa S. Combinatorial roles of nuclear receptors in inflammation and immunity. Nat Rev Immunol. 2006 Jan; 6(1):44-55. PMID: 16493426.
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    173. Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21. PMID: 16143103; PMCID: PMC1430687.
    174. Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature. 2005 Sep 29; 437(7059):759-63. PMID: 16127449; PMCID: PMC1464798.
    175. Lehrke M, Pascual G, Glass CK, Lazar MA. Gaining weight: the Keystone Symposium on PPAR and LXR. Genes Dev. 2005 Aug 01; 19(15):1737-42. PMID: 16077002; PMCID: PMC1182333.
    176. Bradshaw G, Gutierrez A, Miyake JH, Davis KR, Li AC, Glass CK, Curtiss LK, Davis RA. Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11029-34. PMID: 16043712; PMCID: PMC1182426.
    177. Kim TH, Barrera LO, Qu C, Van Calcar S, Trinklein ND, Cooper SJ, Luna RM, Glass CK, Rosenfeld MG, Myers RM, Ren B. Direct isolation and identification of promoters in the human genome. Genome Res. 2005 Jun; 15(6):830-9. PMID: 15899964; PMCID: PMC1142473.
    178. Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, Witztum JL, Dennis EA. A comprehensive classification system for lipids. J Lipid Res. 2005 May; 46(5):839-61. PMID: 15722563.
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    179. Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, Rosenfeld MG. Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell. 2004 Dec 17; 119(6):815-29. PMID: 15607978.
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    180. Valledor AF, Hsu LC, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17813-8. PMID: 15601766; PMCID: PMC539759.
    181. Li AC, Binder CJ, Gutierrez A, Brown KK, Plotkin CR, Pattison JW, Valledor AF, Davis RA, Willson TM, Witztum JL, Palinski W, Glass CK. Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest. 2004 Dec; 114(11):1564-76. PMID: 15578089; PMCID: PMC529277.
    182. Ogawa S, Glass CK. Factor XIIIA (cross)links AT1 receptors to atherosclerosis. Cell. 2004 Oct 29; 119(3):313-4. PMID: 15507203.
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    183. Li AC, Glass CK. PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res. 2004 Dec; 45(12):2161-73. PMID: 15489539.
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    184. Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, Rose DW, Johnson RS, Rosenfeld MG, Glass CK. A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14461-6. PMID: 15452344; PMCID: PMC521940.
    185. Cunard R, Eto Y, Muljadi JT, Glass CK, Kelly CJ, Ricote M. Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma. J Immunol. 2004 Jun 15; 172(12):7530-6. PMID: 15187132.
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    186. Glass CK, McDonnell DP. The jensen symposium; a tribute to a pioneer in the field of nuclear receptor biology. Mol Cell. 2004 Feb 27; 13(4):459-67. PMID: 14992717.
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    187. Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG. A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell. 2004 Feb 20; 116(4):511-26. PMID: 14980219.
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    188. Sawka-Verhelle D, Escoubet-Lozach L, Fong AL, Hester KD, Herzig S, Lebrun P, Glass CK. PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation. J Biol Chem. 2004 Apr 23; 279(17):17772-84. PMID: 14754893.
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    189. Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20; 426(6964):247-54. PMID: 14628042.
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    190. Ricote M, Valledor AF, Glass CK. Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol. 2004 Feb; 24(2):230-9. PMID: 14592855.
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    191. Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK. Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol. 2003 Aug; 23(16):5780-9. PMID: 12897148; PMCID: PMC166346.
    192. Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK. PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6712-7. PMID: 12740443; PMCID: PMC164512.
    193. Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG. Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3245-50. PMID: 12629224; PMCID: PMC152277.
    194. Deguchi K, Ayton PM, Carapeti M, Kutok JL, Snyder CS, Williams IR, Cross NC, Glass CK, Cleary ML, Gilliland DG. MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP. Cancer Cell. 2003 Mar; 3(3):259-71. PMID: 12676584.
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    195. Söderström M, Wigren J, Surapureddi S, Glass CK, Hammarström S. Novel prostaglandin D(2)-derived activators of peroxisome proliferator-activated receptor-gamma are formed in macrophage cell cultures. Biochim Biophys Acta. 2003 Feb 20; 1631(1):35-41. PMID: 12573447.
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    196. Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK, Kelly CJ. WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo. J Immunol. 2002 Dec 15; 169(12):6806-12. PMID: 12471112.
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    197. Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG. Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell. 2002 Nov 27; 111(5):673-85. PMID: 12464179.
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    198. Li AC, Glass CK. The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002 Nov; 8(11):1235-42. PMID: 12411950.
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    199. Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG. Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science. 2002 Nov 29; 298(5599):1747-52. PMID: 12399542.
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    200. Escoubet-Lozach L, Glass CK, Wasserman SI. The role of transcription factors in allergic inflammation. J Allergy Clin Immunol. 2002 Oct; 110(4):553-64. PMID: 12373260.
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    201. Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J Biol Chem. 2002 Nov 08; 277(45):42821-9. PMID: 12215441.
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    202. Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell. 2002 Jul 12; 110(1):55-67. PMID: 12150997.
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    203. Klappacher GW, Glass CK. Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages. Curr Opin Lipidol. 2002 Jun; 13(3):305-12. PMID: 12045401.
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    204. Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 2002 Apr 19; 109(2):169-80. PMID: 12007404.
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    205. Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee YH, Ricote M, Glass CK, Brewer HB, Gonzalez FJ. Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol. 2002 Apr; 22(8):2607-19. PMID: 11909955; PMCID: PMC133709.
    206. Napoli C, de Nigris F, Welch JS, Calara FB, Stuart RO, Glass CK, Palinski W. Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray. Circulation. 2002 Mar 19; 105(11):1360-7. PMID: 11901049.
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    207. Cunard R, Ricote M, DiCampli D, Archer DC, Kahn DA, Glass CK, Kelly CJ. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol. 2002 Mar 15; 168(6):2795-802. PMID: 11884448.
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    208. Hermanson O, Glass CK, Rosenfeld MG. Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol Metab. 2002 Mar; 13(2):55-60. PMID: 11854019.
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    209. Hammarstrom S, Trinks C, Wigren J, Surapureddi S, Soderstrom M, Glass CK. Novel eicosanoid activators of PPAR gamma formed by RAW 264.7 macrophage cultures. Adv Exp Med Biol. 2002; 507:343-9. PMID: 12664608.
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    210. Glass CK. Potential roles of the peroxisome proliferator-activated receptor-gamma in macrophage biology and atherosclerosis. J Endocrinol. 2001 Jun; 169(3):461-4. PMID: 11375116.
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    211. Glass CK, Witztum JL. Atherosclerosis. the road ahead. Cell. 2001 Feb 23; 104(4):503-16. PMID: 11239408.
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