Jeff Hasty

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Title(s)Professor, Bioengineering


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    Georgia Institute of Technology, Atlanta, GAPhD06/1997Physics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Design, mutate, screen: Multiplexed creation and arrayed screening of synchronized genetic clocks. Cell Syst. 2022 May 18; 13(5):365-375.e5. Lezia A, Csicsery N, Hasty J. PMID: 35320733.
      View in: PubMed   Mentions:    Fields:    
    2. Rapid, Affordable, and Uncomplicated Production of Bacterial Cell-free Lysate. J Vis Exp. 2021 10 29; (176). Cooper RM, Tonooka T, Didovyk A, Hasty J. PMID: 34779438.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. The microbiome and human cancer. Science. 2021 03 26; 371(6536). Sepich-Poore GD, Zitvogel L, Straussman R, Hasty J, Wargo JA, Knight R. PMID: 33766858; PMCID: PMC8767999.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    4. Survival of the weakest in non-transitive asymmetric interactions among strains of E. coli. Nat Commun. 2020 11 27; 11(1):6055. Liao MJ, Miano A, Nguyen CB, Chao L, Hasty J. PMID: 33247128; PMCID: PMC7699631.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    5. A programmable fate decision landscape underlies single-cell aging in yeast. Science. 2020 Jul 17; 369(6501):325-329. Li Y, Jiang Y, Paxman J, O'Laughlin R, Klepin S, Zhu Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 32675375; PMCID: PMC7437498.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    6. Interfacing gene circuits with microelectronics through engineered population dynamics. Sci Adv. 2020 05; 6(21):eaaz8344. Din MO, Martin A, Razinkov I, Csicsery N, Hasty J. PMID: 32494744; PMCID: PMC7244307.
      View in: PubMed   Mentions: 7     Fields:    
    7. One-Day Construction of Multiplex Arrays to Harness Natural CRISPR-Cas Systems. ACS Synth Biol. 2020 05 15; 9(5):1129-1137. Cooper RM, Hasty J. PMID: 32271547; PMCID: PMC8173669.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Genetically engineered control of phenotypic structure in microbial colonies. Nat Microbiol. 2020 05; 5(5):697-705. Bittihn P, Didovyk A, Tsimring LS, Hasty J. PMID: 32284568; PMCID: PMC8172263.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    9. Inducible cell-to-cell signaling for tunable dynamics in microbial communities. Nat Commun. 2020 03 04; 11(1):1193. Miano A, Liao MJ, Hasty J. PMID: 32132536; PMCID: PMC7055273.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    10. Genome-scale transcriptional dynamics and environmental biosensing. Proc Natl Acad Sci U S A. 2020 02 11; 117(6):3301-3306. Graham G, Csicsery N, Stasiowski E, Thouvenin G, Mather WH, Ferry M, Cookson S, Hasty J. PMID: 31974311; PMCID: PMC7022183.
      View in: PubMed   Mentions: 3     Fields:    Translation:CellsPHPublic Health
    11. Flower-like patterns in multi-species bacterial colonies. Elife. 2020 01 14; 9. Xiong L, Cao Y, Cooper R, Rappel WJ, Hasty J, Tsimring L. PMID: 31933477; PMCID: PMC6959979.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    12. Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiae. Transl Med Aging. 2020; 4:151-160. O'Laughlin R, Jin M, Li Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 33880425; PMCID: PMC8054985.
      View in: PubMed   Mentions: 1  
    13. Rock-paper-scissors: Engineered population dynamics increase genetic stability. Science. 2019 09 06; 365(6457):1045-1049. Liao MJ, Din MO, Tsimring L, Hasty J. PMID: 31488693; PMCID: PMC6988775.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    14. Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics. Cell Syst. 2019 03 27; 8(3):242-253.e3. Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 30852250; PMCID: PMC6514117.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    15. Microfluidics-Based Analysis of Contact-dependent Bacterial Interactions. Bio Protoc. 2018 Aug 20; 8(16). Cooper R, Tsimring L, Hasty J. PMID: 30370317; PMCID: PMC6200413.
      View in: PubMed   Mentions:
    16. Rational engineering of synthetic microbial systems: from single cells to consortia. Curr Opin Microbiol. 2018 10; 45:92-99. Bittihn P, Din MO, Tsimring LS, Hasty J. PMID: 29574330; PMCID: PMC6151159.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    17. Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance. Elife. 2017 11 01; 6. Cooper RM, Tsimring L, Hasty J. PMID: 29091031; PMCID: PMC5701796.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    18. Multigenerational silencing dynamics control cell aging. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11253-11258. Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 29073021; PMCID: PMC5651738.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    19. Rapid and Scalable Preparation of Bacterial Lysates for Cell-Free Gene Expression. ACS Synth Biol. 2017 12 15; 6(12):2198-2208. Didovyk A, Tonooka T, Tsimring L, Hasty J. PMID: 28795570; PMCID: PMC6038143.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    20. Synchronized DNA cycling across a bacterial population. Nat Genet. 2017 Aug; 49(8):1282-1285. Baumgart L, Mather W, Hasty J. PMID: 28692067.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    21. A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis. Nat Microbiol. 2017 Jun 12; 2:17083. Scott SR, Din MO, Bittihn P, Xiong L, Tsimring LS, Hasty J. PMID: 28604679; PMCID: PMC5603288.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    22. Suppression of Beneficial Mutations in Dynamic Microbial Populations. Phys Rev Lett. 2017 Jan 13; 118(2):028102. Bittihn P, Hasty J, Tsimring LS. PMID: 28128631; PMCID: PMC5552243.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    23. FBB: a fast Bayesian-bound tool to calibrate RNA-seq aligners. Bioinformatics. 2017 01 15; 33(2):210-218. Rodriguez-Lujan I, Hasty J, Huerta R. PMID: 27663496.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    24. Criticality and Adaptivity in Enzymatic Networks. Biophys J. 2016 Sep 06; 111(5):1078-87. Steiner PJ, Williams RJ, Hasty J, Tsimring LS. PMID: 27602735; PMCID: PMC5018143.
      View in: PubMed   Mentions: 5     Fields:    
    25. Synchronized cycles of bacterial lysis for in vivo delivery. Nature. 2016 08 04; 536(7614):81-85. Din MO, Danino T, Prindle A, Skalak M, Selimkhanov J, Allen K, Julio E, Atolia E, Tsimring LS, Bhatia SN, Hasty J. PMID: 27437587; PMCID: PMC5048415.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    26. Transcriptional regulation with CRISPR-Cas9: principles, advances, and applications. Curr Opin Biotechnol. 2016 08; 40:177-184. Didovyk A, Borek B, Tsimring L, Hasty J. PMID: 27344519; PMCID: PMC4975649.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    27. Quorum Sensing Communication Modules for Microbial Consortia. ACS Synth Biol. 2016 09 16; 5(9):969-77. Scott SR, Hasty J. PMID: 27172092; PMCID: PMC5603278.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    28. Turing Patterning Using Gene Circuits with Gas-Induced Degradation of Quorum Sensing Molecules. PLoS One. 2016; 11(5):e0153679. Borek B, Hasty J, Tsimring L. PMID: 27148743; PMCID: PMC4858293.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    29. Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9. ACS Synth Biol. 2016 Jan 15; 5(1):81-8. Didovyk A, Borek B, Hasty J, Tsimring L. PMID: 26390083; PMCID: PMC5462464.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    30. A Microfluidic Platform for Long-Term Monitoring of Algae in a Dynamic Environment. ACS Synth Biol. 2016 Jan 15; 5(1):8-14. Luke CS, Selimkhanov J, Baumgart L, Cohen SE, Golden SS, Cookson NA, Hasty J. PMID: 26332284; PMCID: PMC5249263.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    31. Distributed classifier based on genetically engineered bacterial cell cultures. ACS Synth Biol. 2015 Jan 16; 4(1):72-82. Didovyk A, Kanakov OI, Ivanchenko MV, Hasty J, Huerta R, Tsimring L. PMID: 25349924; PMCID: PMC4304444.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    32. Dynamic localization of the cyanobacterial circadian clock proteins. Curr Biol. 2014 Aug 18; 24(16):1836-44. Cohen SE, Erb ML, Selimkhanov J, Dong G, Hasty J, Pogliano J, Golden SS. PMID: 25127213; PMCID: PMC4139467.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    33. Rapid and tunable post-translational coupling of genetic circuits. Nature. 2014 Apr 17; 508(7496):387-91. Prindle A, Selimkhanov J, Li H, Razinkov I, Tsimring LS, Hasty J. PMID: 24717442; PMCID: PMC4142690.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    34. Measuring competitive fitness in dynamic environments. J Phys Chem B. 2013 Oct 24; 117(42):13175-81. Razinkov IA, Baumgartner BL, Bennett MR, Tsimring LS, Hasty J. PMID: 23841812; PMCID: PMC3808460.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    35. Dual delayed feedback provides sensitivity and robustness to the NF-κB signaling module. PLoS Comput Biol. 2013; 9(6):e1003112. Longo DM, Selimkhanov J, Kearns JD, Hasty J, Hoffmann A, Tsimring LS. PMID: 23825938; PMCID: PMC3694842.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    36. Vacuum-assisted cell loading enables shear-free mammalian microfluidic culture. Lab Chip. 2012 Nov 21; 12(22):4732-7. Kolnik M, Tsimring LS, Hasty J. PMID: 22961584; PMCID: PMC3510264.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    37. Making gene circuits sing. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16758-9. Prindle A, Hasty J. PMID: 23027956; PMCID: PMC3479459.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    38. Genetic Circuits in Salmonella typhimurium. ACS Synth Biol. 2012 Oct 19; 1(10):458-464. Prindle A, Selimkhanov J, Danino T, Samayoa P, Goldberg A, Bhatia SN, Hasty J. PMID: 23097749; PMCID: PMC3477097.
      View in: PubMed   Mentions: 12     Fields:    
    39. Fast stochastic algorithm for simulating evolutionary population dynamics. Bioinformatics. 2012 May 01; 28(9):1230-8. Mather WH, Hasty J, Tsimring LS. PMID: 22437850; PMCID: PMC3338019.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    40. Queueing up for enzymatic processing: correlated signaling through coupled degradation. Mol Syst Biol. 2011 Dec 20; 7:561. Cookson NA, Mather WH, Danino T, Mondragón-Palomino O, Williams RJ, Tsimring LS, Hasty J. PMID: 22186735; PMCID: PMC3737734.
      View in: PubMed   Mentions: 61     Fields:    Translation:Cells
    41. A sensing array of radically coupled genetic 'biopixels'. Nature. 2011 Dec 18; 481(7379):39-44. Prindle A, Samayoa P, Razinkov I, Danino T, Tsimring LS, Hasty J. PMID: 22178928; PMCID: PMC3259005.
      View in: PubMed   Mentions: 109     Fields:    Translation:Cells
    42. Antagonistic gene transcripts regulate adaptation to new growth environments. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21087-92. Baumgartner BL, Bennett MR, Ferry M, Johnson TL, Tsimring LS, Hasty J. PMID: 22160690; PMCID: PMC3248483.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    43. Recent advances in single-cell studies of gene regulation. Curr Opin Biotechnol. 2012 Feb; 23(1):34-40. Selimkhanov J, Hasty J, Tsimring LS. PMID: 22154220; PMCID: PMC3273644.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    44. Factorized time-dependent distributions for certain multiclass queueing networks and an application to enzymatic processing networks. Queueing Syst. 2011 Dec; 69(3-4):313-328. Mather WH, Hasty J, Tsimring LS, Williams RJ. PMID: 24596432; PMCID: PMC3939083.
      View in: PubMed   Mentions: 3  
    45. Entrainment of a population of synthetic genetic oscillators. Science. 2011 Sep 02; 333(6047):1315-1319. Mondragón-Palomino O, Danino T, Selimkhanov J, Tsimring L, Hasty J. PMID: 21885786; PMCID: PMC4841678.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    46. In-silico patterning of vascular mesenchymal cells in three dimensions. PLoS One. 2011; 6(5):e20182. Danino T, Volfson D, Bhatia SN, Tsimring L, Hasty J. PMID: 21633504; PMCID: PMC3102094.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    47. Microfluidics for synthetic biology: from design to execution. Methods Enzymol. 2011; 497:295-372. Ferry MS, Razinkov IA, Hasty J. PMID: 21601093; PMCID: PMC4836382.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    48. Correlation resonance generated by coupled enzymatic processing. Biophys J. 2010 Nov 17; 99(10):3172-81. Mather WH, Cookson NA, Hasty J, Tsimring LS, Williams RJ. PMID: 21081064; PMCID: PMC2980735.
      View in: PubMed   Mentions: 14     Fields:    
    49. Biochemistry. Stochastic emergence of groupthink. Science. 2010 May 21; 328(5981):987-8. Prindle A, Hasty J. PMID: 20489014; PMCID: PMC2931587.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    50. Streaming instability in growing cell populations. Phys Rev Lett. 2010 May 21; 104(20):208101. Mather W, Mondragón-Palomino O, Danino T, Hasty J, Tsimring LS. PMID: 20867071; PMCID: PMC2947335.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    51. A synchronized quorum of genetic clocks. Nature. 2010 Jan 21; 463(7279):326-30. Danino T, Mondragón-Palomino O, Tsimring L, Hasty J. PMID: 20090747; PMCID: PMC2838179.
      View in: PubMed   Mentions: 286     Fields:    Translation:Cells
    52. The pedestrian watchmaker: genetic clocks from engineered oscillators. FEBS Lett. 2009 Dec 17; 583(24):3931-7. Cookson NA, Tsimring LS, Hasty J. PMID: 19903483; PMCID: PMC2921805.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    53. Cell cycle-dependent variations in protein concentration. Nucleic Acids Res. 2010 May; 38(8):2676-81. Cookson NA, Cookson SW, Tsimring LS, Hasty J. PMID: 20019065; PMCID: PMC2860113.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    54. Delay-induced degrade-and-fire oscillations in small genetic circuits. Phys Rev Lett. 2009 Feb 13; 102(6):068105. Mather W, Bennett MR, Hasty J, Tsimring LS. PMID: 19257639; PMCID: PMC2924583.
      View in: PubMed   Mentions: 51     Fields:    
    55. A fast, robust and tunable synthetic gene oscillator. Nature. 2008 Nov 27; 456(7221):516-9. Stricker J, Cookson S, Bennett MR, Mather WH, Tsimring LS, Hasty J. PMID: 18971928; PMCID: PMC6791529.
      View in: PubMed   Mentions: 403     Fields:    Translation:Cells
    56. Biomechanical ordering of dense cell populations. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15346-51. Volfson D, Cookson S, Hasty J, Tsimring LS. PMID: 18832176; PMCID: PMC2563119.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    57. Metabolic gene regulation in a dynamically changing environment. Nature. 2008 Aug 28; 454(7208):1119-22. Bennett MR, Pang WL, Ostroff NA, Baumgartner BL, Nayak S, Tsimring LS, Hasty J. PMID: 18668041; PMCID: PMC2654342.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    58. Phenotypic variability of growing cellular populations. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18982-7. Lu T, Shen T, Bennett MR, Wolynes PG, Hasty J. PMID: 18025471; PMCID: PMC2141894.
      View in: PubMed   Mentions: 15     Fields:    
    59. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae. Mol Syst Biol. 2007; 3:127. Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. PMID: 17667949; PMCID: PMC1943424.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    60. Transient dynamics of genetic regulatory networks. Biophys J. 2007 May 15; 92(10):3501-12. Bennett MR, Volfson D, Tsimring L, Hasty J. PMID: 17350994; PMCID: PMC1853127.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    61. Dynamics of single-cell gene expression. Mol Syst Biol. 2006; 2:64. Longo D, Hasty J. PMID: 17130866; PMCID: PMC1682029.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    62. Statistics of cellular signal transduction as a race to the nucleus by multiple random walkers in compartment/phosphorylation space. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16752-7. Lu T, Shen T, Zong C, Hasty J, Wolynes PG. PMID: 17071742; PMCID: PMC1636527.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    63. Stochastically driven genetic circuits. Chaos. 2006 Jun; 16(2):026103. Tsimring LS, Volfson D, Hasty J. PMID: 16822035.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    64. Effective temperature in stochastic kinetics and gene networks. Biophys J. 2006 Jul 01; 91(1):84-94. Lu T, Hasty J, Wolynes PG. PMID: 16617067; PMCID: PMC1479063.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    65. Origins of extrinsic variability in eukaryotic gene expression. Nature. 2006 Feb 16; 439(7078):861-4. Volfson D, Marciniak J, Blake WJ, Ostroff N, Tsimring LS, Hasty J. PMID: 16372021.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    66. Monitoring dynamics of single-cell gene expression over multiple cell cycles. Mol Syst Biol. 2005; 1:2005.0024. Cookson S, Ostroff N, Pang WL, Volfson D, Hasty J. PMID: 16729059; PMCID: PMC1681470.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    67. Delay-induced stochastic oscillations in gene regulation. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14593-8. Bratsun D, Volfson D, Tsimring LS, Hasty J. PMID: 16199522; PMCID: PMC1253555.
      View in: PubMed   Mentions: 108     Fields:    
    68. Cellular growth and division in the Gillespie algorithm. Syst Biol (Stevenage). 2004 Jun; 1(1):121-8. Lu T, Volfson D, Tsimring L, Hasty J. PMID: 17052122.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    69. Design then mutate. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):16516-8. Hasty J. PMID: 12486244; PMCID: PMC139174.
      View in: PubMed   Mentions:    Fields:    
    70. Engineered gene circuits. Nature. 2002 Nov 14; 420(6912):224-30. Hasty J, McMillen D, Collins JJ. PMID: 12432407.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
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