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Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. Diabetes. 2022 12 01; 71(12):2513-2529.
Ramms B, Pollow DP, Zhu H, Nora C, Harrington AR, Omar I, Gordts PLSM, Wortham M, Sander M. PMID: 36162056; PMCID: PMC9750949.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering. JCI Insight. 2022 07 08; 7(13).
Ramms B, Patel S, Sun X, Pessentheiner AR, Ducasa GM, Mullick AE, Lee RG, Crooke RM, Tsimikas S, Witztum JL, Gordts PL. PMID: 35653195; PMCID: PMC9310539.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation. J Biol Chem. 2022 08; 298(8):102159.
Tillo M, Lamanna WC, Dwyer CA, Sandoval DR, Pessentheiner AR, Al-Azzam N, Sarrazin S, Gonzales JC, Kan SH, Andreyev AY, Schultheis N, Thacker BE, Glass CA, Dickson PI, Wang RY, Selleck SB, Esko JD, Gordts PLSM. PMID: 35750212; PMCID: PMC9364035.
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PubMed Mentions: Fields:
Translation:
Animals
-
Biologically Derived Neoproteoglycans for Profiling Protein-Glycosaminoglycan Interactions. ACS Chem Biol. 2022 06 17; 17(6):1534-1542.
Porell RN, Follmar JL, Purcell SC, Timm B, Laubach LK, Kozirovskiy D, Thacker BE, Glass CA, Gordts PLSM, Godula K. PMID: 35574759.
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PubMed Mentions: Fields:
Translation:
HumansCells
-
Author Correction: Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2022 May; 18(5):575.
Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 35354934.
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PubMed Mentions: Fields:
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Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report. Arterioscler Thromb Vasc Biol. 2021 11; 41(11):2730-2739.
Kawanishi K, Coker JK, Grunddal KV, Dhar C, Hsiao J, Zengler K, Varki N, Varki A, Gordts PLSM. PMID: 34587757; PMCID: PMC8551057.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2021 06; 17(6):684-692.
Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD. PMID: 33846619; PMCID: PMC8159865.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021 Mar 26.
Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM. PMID: 33791697; PMCID: PMC8010724.
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PubMed Mentions:
-
microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production. JCI Insight. 2020 12 03; 5(23).
Dong J, He M, Li J, Pessentheiner A, Wang C, Zhang J, Sun Y, Wang WT, Zhang Y, Liu J, Wang SC, Huang PH, Gordts PL, Yuan ZY, Tsimikas S, Shyy JY. PMID: 33119548; PMCID: PMC7714402.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020 11 12; 183(4):1043-1057.e15.
Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32970989; PMCID: PMC7489987.
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PubMed Mentions:
488 Fields:
Translation:
HumansCellsPHPublic Health
-
Corrigendum to: Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants. Glycobiology. 2020 08 20; 30(9):760.
Anower-E-Khuda F, Singh G, Deng Y, Gordts PLSM, Esko JD. PMID: 32091093; PMCID: PMC7443331.
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PubMed Mentions: Fields:
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Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. J Biol Chem. 2020 Jul 24; 295(30):10508.
Poli M, Anower-E-Khuda F, Asperti M, Ruzzenenti P, Gryzik M, Denardo A, Gordts PLSM, Arosio P, Esko JD. PMID: 32709762; PMCID: PMC7383380.
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PubMed Mentions: Fields:
-
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. bioRxiv. 2020 Jul 14.
Clausen TM, Sandoval DR, Spliid CB, Pihl J, Painter CD, Thacker BE, Glass CA, Narayanan A, Majowicz SA, Zhang Y, Torres JL, Golden GJ, Porell R, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser B, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Leibel SL, Chanda SK, Schmidt AG, Godula K, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. PMID: 32699853; PMCID: PMC7373134.
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PubMed Mentions:
2
-
Statin therapy increases lipoprotein(a) levels. Eur Heart J. 2020 06 21; 41(24):2275-2284.
Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31111151.
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PubMed Mentions:
79 Fields:
Translation:
Humans
-
Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation. Front Immunol. 2020; 11:769.
Pessentheiner AR, Ducasa GM, Gordts PLSM. PMID: 32508807; PMCID: PMC7248225.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
-
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9311-9317.
Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. PMID: 32277030; PMCID: PMC7196839.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
Correction: Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. J Biol Chem. 2020 Mar 13; 295(11):3747.
Poli M, Anower-E-Khuda F, Asperti M, Ruzzenenti P, Gryzik M, Denardo A, Gordts PLSM, Arosio P, Esko JD. PMID: 32169857; PMCID: PMC7076228.
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PubMed Mentions: Fields:
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Corrigendum to "The heparan sulfate proteoglycan grip on hyperlipidemia and atherosclerosis" [Matrix Biol. 71-72 (2018) 262-282]. Matrix Biol. 2020 06; 88:89.
Gordts PLSM, Esko JD. PMID: 32144003.
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PubMed Mentions: Fields:
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Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):1847-1848.
Kawanishi K, Dhar C, Varki A, Gordts PLSM. PMID: 31964837; PMCID: PMC6994995.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Statins and increases in Lp(a): an inconvenient truth that needs attention. Eur Heart J. 2020 01 01; 41(1):192-193.
Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. PMID: 31893480.
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PubMed Mentions:
9 Fields:
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ApoC-III Glycoforms Are Differentially Cleared by Hepatic TRL (Triglyceride-Rich Lipoprotein) Receptors. Arterioscler Thromb Vasc Biol. 2019 10; 39(10):2145-2156.
Kegulian NC, Ramms B, Horton S, Trenchevska O, Nedelkov D, Graham MJ, Lee RG, Esko JD, Yassine HN, Gordts PLSM. PMID: 31390883; PMCID: PMC6761044.
-
Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):16036-16045.
Kawanishi K, Dhar C, Do R, Varki N, Gordts PLSM, Varki A. PMID: 31332008; PMCID: PMC6690033.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Triglyceride-rich lipoprotein binding and uptake by heparan sulfate proteoglycan receptors in a CRISPR/Cas9 library of Hep3B mutants. Glycobiology. 2019 07 19; 29(8):582-592.
Anower-E-Khuda F, Singh G, Deng Y, Gordts PLSM, Esko JD. PMID: 31094413; PMCID: PMC6639542.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. J Biol Chem. 2019 09 06; 294(36):13292-13303.
Poli M, Anower-E-Khuda F, Asperti M, Ruzzenenti P, Gryzik M, Denardo A, Gordts PLSM, Arosio P, Esko JD. PMID: 31315930; PMCID: PMC6737225.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance. J Lipid Res. 2019 08; 60(8):1379-1395.
Ramms B, Patel S, Nora C, Pessentheiner AR, Chang MW, Green CR, Golden GJ, Secrest P, Krauss RM, Metallo CM, Benner C, Alexander VJ, Witztum JL, Tsimikas S, Esko JD, Gordts PLSM. PMID: 31092690; PMCID: PMC6672034.
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PubMed Mentions:
20 Fields:
Translation:
Animals
-
Hyaluronan as a potential thermogenic rheostat. Nat Metab. 2019 05; 1(5):503-504.
Gordts PLSM, Saltiel AR. PMID: 32694849.
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PubMed Mentions: Fields:
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LRP1 Has a Predominant Role in Production over Clearance of A� in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2019 Oct; 56(10):7234-7245.
Van Gool B, Storck SE, Reekmans SM, Lechat B, Gordts PLSM, Pradier L, Pietrzik CU, Roebroek AJM. PMID: 31004319; PMCID: PMC6728278.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles. Biochim Biophys Acta Mol Basis Dis. 2019 06 01; 1865(6):1592-1603.
Fischer AW, Albers K, Schlein C, Sass F, Krott LM, Schmale H, Gordts PLSM, Scheja L, Heeren J. PMID: 30904610; PMCID: PMC6624118.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface. Bioconjug Chem. 2019 03 20; 30(3):833-840.
Trieger GW, Verespy S, Gordts PLSM, Godula K. PMID: 30668905; PMCID: PMC6860979.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Deletion of Lymphangiogenic and Angiogenic Growth Factor VEGF-D Leads to Severe Hyperlipidemia and Delayed Clearance of Chylomicron Remnants. Arterioscler Thromb Vasc Biol. 2018 10; 38(10):2327-2337.
Tirronen A, Vuorio T, Kettunen S, Hokkanen K, Ramms B, Niskanen H, Laakso H, Kaikkonen MU, Jauhiainen M, Gordts PLSM, Yl?-Herttuala S. PMID: 30354205.
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PubMed Mentions:
14 Fields:
Translation:
Animals
-
The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins. Mol Metab. 2018 10; 16:88-99.
Fischer AW, Albers K, Krott LM, Hoffzimmer B, Heine M, Schmale H, Scheja L, Gordts PLSM, Heeren J. PMID: 30100244; PMCID: PMC6158030.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism. Curr Opin Lipidol. 2018 06; 29(3):171-179.
Ramms B, Gordts PLSM. PMID: 29547399.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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The heparan sulfate proteoglycan grip on hyperlipidemia and atherosclerosis. Matrix Biol. 2018 10; 71-72:262-282.
Gordts PLSM, Esko JD. PMID: 29803939; PMCID: PMC6432921.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
AIBP protects against metabolic abnormalities and atherosclerosis. J Lipid Res. 2018 05; 59(5):854-863.
Schneider DA, Choi SH, Agatisa-Boyle C, Zhu L, Kim J, Pattison J, Sears DD, Gordts PLSM, Fang L, Miller YI. PMID: 29559522; PMCID: PMC5928435.
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PubMed Mentions:
23 Fields:
Translation:
Animals
-
Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms. J Virol. 2018 03 15; 92(6).
Clark AE, Sabalza M, Gordts PLSM, Spector DH. PMID: 29237845; PMCID: PMC5827393.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
ANGPTL3 targeting: The power of versatile lipid-lowering. Atherosclerosis. 2018 01; 268:185-187.
Pessentheiner AR, Ramms B, Gordts PLSM. PMID: 29111225.
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PubMed Mentions: Fields:
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Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain. Mol Ther. 2017 Dec 06; 25(12):2743-2752.
Tong W, Dwyer CA, Thacker BE, Glass CA, Brown JR, Hamill K, Moremen KW, Sarrazin S, Gordts PLSM, Dozier LE, Patrick GN, Tor Y, Esko JD. PMID: 28958576; PMCID: PMC5768556.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgRKT to the List. Circ Res. 2017 03 31; 120(7):1050-1052.
Yeang C, Gordts PL, Tsimikas S. PMID: 28360338; PMCID: PMC5470738.
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PubMed Mentions:
5 Fields:
-
Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431?239 Patients. Arterioscler Thromb Vasc Biol. 2017 Mar; 37(3):580-588.
Moriarty PM, Varvel SA, Gordts PL, McConnell JP, Tsimikas S. PMID: 28062489; PMCID: PMC5323356.
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PubMed Mentions:
29 Fields:
Translation:
Humans
-
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors. J Clin Invest. 2016 08 01; 126(8):2855-66.
Gordts PL, Nock R, Son NH, Ramms B, Lew I, Gonzales JC, Thacker BE, Basu D, Lee RG, Mullick AE, Graham MJ, Goldberg IJ, Crooke RM, Witztum JL, Esko JD. PMID: 27400128; PMCID: PMC4966320.
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PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
-
Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I. PLoS One. 2016; 11(3):e0150850.
Khalid O, Vera MU, Gordts PL, Ellinwood NM, Schwartz PH, Dickson PI, Esko JD, Wang RY. PMID: 26986213; PMCID: PMC4795702.
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PubMed Mentions:
16 Fields:
Translation:
Animals
-
Dietary nitrate struggles in atherosclerosis. Atherosclerosis. 2016 Feb; 245:71-3.
Ramms B, Gordts PL. PMID: 26708286.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Small molecule antagonists of cell-surface heparan sulfate and heparin-protein interactions. Chem Sci. 2015 Oct 01; 6(10):5984-5993.
Weiss RJ, Gordts PL, Le D, Xu D, Esko JD, Tor Y. PMID: 28133533; PMCID: PMC5267326.
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PubMed Mentions:
11
-
Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015 May; 47(5):528-34.
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PL, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagiroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, M?ller U, Desguerre I, Casanova JL, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG. PMID: 25848753; PMCID: PMC4414867.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015 Mar 10; 6:6356.
Berb?e JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. PMID: 25754609; PMCID: PMC4366535.
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PubMed Mentions:
173 Fields:
Translation:
Animals
-
Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans. J Lipid Res. 2015 Mar; 56(3):665-673.
Mooij HL, Bernelot Moens SJ, Gordts PSM, Stanford K, Foley E, van den Boogert MW, Witjes J, Hassing HC, Tanck M, van de Sande MJ, Levels JH, Kastelein JP, Stroes EG, Dallinga-Thie G, Esko J, Nieuwdorp M. PMID: 25568062; PMCID: PMC4340313.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Heparan sulfate proteoglycans fine-tune macrophage inflammation via IFN-�. Cytokine. 2015 Mar; 72(1):118-9.
Gordts PL, Esko JD. PMID: 25573804.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
-
Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. Cell Metab. 2014 Nov 04; 20(5):813-826.
Gordts PLSM, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. PMID: 25440058; PMCID: PMC4254584.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice. Arterioscler Thromb Vasc Biol. 2013 Sep; 33(9):2065-74.
Foley EM, Gordts PLSM, Stanford KI, Gonzales JC, Lawrence R, Stoddard N, Esko JD. PMID: 23846497; PMCID: PMC3821931.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. J Clin Invest. 2013 Jun; 123(6):2742-51.
Gonzales JC, Gordts PL, Foley EM, Esko JD. PMID: 23676495; PMCID: PMC3668842.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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A genetic model of substrate reduction therapy for mucopolysaccharidosis. J Biol Chem. 2012 Oct 19; 287(43):36283-90.
Lamanna WC, Lawrence R, Sarrazin S, Lameda-Diaz C, Gordts PL, Moremen KW, Esko JD. PMID: 22952226; PMCID: PMC3476295.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles. J Lipid Res. 2012 Oct; 53(10):2198-2204.
Christoffersen C, Benn M, Christensen PM, Gordts PLSM, Roebroek AJM, Frikke-Schmidt R, Tybjaerg-Hansen A, Dahlb?ck B, Nielsen LB. PMID: 22826357; PMCID: PMC3435552.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One. 2012; 7(6):e38330.
Gordts PL, Bartelt A, Nilsson SK, Annaert W, Christoffersen C, Nielsen LB, Heeren J, Roebroek AJ. PMID: 22701627; PMCID: PMC3368875.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance. Hepatology. 2012 Jan; 55(1):277-86.
Deng Y, Foley EM, Gonzales JC, Gordts PL, Li Y, Esko JD. PMID: 21898481; PMCID: PMC3245353.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Brown adipose tissue activity controls triglyceride clearance. Nat Med. 2011 Feb; 17(2):200-5.
Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychm?ller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. PMID: 21258337.
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PubMed Mentions:
703 Fields:
Translation:
HumansAnimals
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Generation of a series of knock-in alleles using RMCE in ES cells. Methods Mol Biol. 2011; 693:277-81.
Roebroek AJ, Gordts PL, Reekmans S. PMID: 21080286.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Knock-in approaches. Methods Mol Biol. 2011; 693:257-75.
Roebroek AJ, Gordts PL, Reekmans S. PMID: 21080285.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis. Circ Res. 2010 May 28; 106(10):1624-34.
Christoffersen C, Pedersen TX, Gordts PL, Roebroek AJ, Dahlbäck B, Nielsen LB. PMID: 20360257.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis. Cell Mol Life Sci. 2010 Jan; 67(1):135-45.
Reekmans SM, Pflanzner T, Gordts PL, Isbert S, Zimmermann P, Annaert W, Weggen S, Roebroek AJ, Pietrzik CU. PMID: 19856143.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Sep; 29(9):1258-64.
Gordts PL, Reekmans S, Lauwers A, Van Dongen A, Verbeek L, Roebroek AJ. PMID: 19667105.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells